COV CATNAP

Compile, Analyze and Tally NAb Panels

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•  Antibody and Virus 
•  Study 
•  Antibody, Virus and Study  

Antibodies by Names    Attributes     Your list		Viruses by    Names      Attributes       Your list
Select all Name Binding type # of viruses tested     (# of Antibodies)     Provide antibody names (one per line) Paste or upload Tip: Names must be the CATNAP standard names .		Select all Name # of Abs tested Seq     Select all Name Reference # of viruses     (# of Viruses)     Provide virus names (one per line) Paste or upload Tip: Names must be the CATNAP standard names .

Retrieve	Antibody details Virus details Assay
Or
Analyze	Assay along with virus sequences    IC50 IC80 IC90 ID50       Select assay method(s)                  Include tests beyond threshold of detection in geometric mean estimates (set to 100 (ICxx) or 20 (ID/IUxx))       Exclude viruses having no sequence data       Include only SARS-CoV-2 sequences       Include only VOI/VOC/VUMs       Show resistance relative to D614G       Email results (Large sets of data run slowly. Limit the number of antibodies/viruses or choose email results)

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• We greatfully acknowledge the Oxford University CoV-AbDab, described by Raybould et al. 2021, as the source of most of the antibody sequence and germline data that we include.
• The statistical analysis follows Gnanakaran et al. 2010.
• The tool interface and database are based on HIV CATNAP, designed by Hyejin Yoon, Jennifer Macke, Bette Korber, and Karina Yusim.

• When using this tool in a publication, please cite:
  • Yoon, H., Macke, J.P., Montefiori, D., Shen, X., and Korber, B. CATNAP Antibody and Sequence Relationships for SARS-CoV-2. Manuscript in preparation.
  • Yoon et al. CATNAP: a tool to compile, analyze and tally neutralizing antibody panels. Nucleic Acid Res 2015 Jul 1;43(W1):W213-9. PMID 26044712.

• We accept SARS-CoV-2 antibody neutralization data submitted directly by authors.
• We welcome suggestions of published neutralization data for addition to CATNAP.
• Please contact us for details.