COVID-19 Viral Genome Analysis Pipeline
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Frequency Changes in Common Forms
Last update: May 15, 2024
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SPIKE sequences: Exhaustive list of Last 60 days, Global, Do not break out by lineage
Compute mutations relative to XBB.1.5 baseline sequence
As new lineages emerge, there are often many sequences with many ambiguous base calls. Our pipeline filters out such sequences, and as a consequence we undercount the number of sequences in GISAID that have been specified as members of related Pango lineages. Our strategy, however, enables us to use strictly high quality sequences to identify and track the common forms in emerging lineages.
COMMON FORMS CHANGES FOR SPIKE WITH A GIVEN PANGO LINEAGE DESIGNATION
For each lineage, we show the most common forms of SPIKE, and we show the forms that are most significantly increasing or decreasing. Also shown is the Hamming distance (HD) between each form and the most common form in that lineage. Deletions relative to the baseline reference strain are indicated with a dash (e.g. the two amino acid deletion at positions 156-157 is indicated with 'E156-,F157-'), and insertions are denoted by a plus sign (e.g. an extra T at position 143 is written '+143T'). Abs Differences in later vs early fractions, expressed as percent. Relative Differences range between -100% and +100%, using formula: rel = 100*(later-early)/max(later,early) percent, applied to the early and later fractions. The p-value associated with increase or decrease is computed by Fisher's exact test, and is meant to be used only as a rough guide to the significance of the change. Since the computation is based on assumptions (such as independent and unbiased sampling) that may not hold in practice, the p-value should not be taken too literally. The first line of each lineage section indicates counts for the full lineage relative to all the sequences. 'Lineage Count' in this first line is actually the full sequence count. 'Form Count' in this first line is actually the full lineage count, and 'Form Pct' refers to lineage count relative to full sequence set.
We show all the forms.
[Note: Mutation strings are relative to baseline XBB.1.5].
This output is based on 16773 sequences sampled from 2024-03-09 to 2024-05-08
This total interval is split into two sub-intervals.
Total: 2024-03-09 to 2024-05-08 (16773)
Early: 2024-03-09 to 2024-03-25 (8277)
Later: 2024-03-26 to 2024-05-08 (8496)
Baseline XBB.1.5: [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
Pango Lineage Form Form Counts Fractions Differences Lineage Count Count Pct Early/Later Early/Later Abs Relative pval HD [Form as mutation string] N/A 16773 3616 21.6% 2264/1352 0.27353/0.15913 -11.44% -41.8% <1e-10 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) N/A 16773 1645 9.8% 992/653 0.11985/0.07686 -4.30% -35.9% <1e-10 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 895 5.3% 450/445 0.05437/0.05238 -0.20% -3.7% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 811 4.8% 371/440 0.04482/0.05179 +0.70% +13.5% 4e-2 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 461 2.7% 192/269 0.02320/0.03166 +0.85% +26.7% 8e-4 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 387 2.3% 64/323 0.00773/0.03802 +3.03% +79.7% <1e-10 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 383 2.3% 42/341 0.00507/0.04014 +3.51% +87.4% <1e-10 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 324 1.9% 133/191 0.01607/0.02248 +0.64% +28.5% 3e-3 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 213 1.3% 135/78 0.01631/0.00918 -0.71% -43.7% 4e-5 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 191 1.1% 62/129 0.00749/0.01518 +0.77% +50.7% 3e-6 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 189 1.1% 79/110 0.00954/0.01295 +0.34% +26.3% 4e-2 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 177 1.1% 84/93 0.01015/0.01095 +0.08% +7.3% 7e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 146 0.9% 67/79 0.00809/0.00930 +0.12% +12.9% 4e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 105 0.6% 34/71 0.00411/0.00836 +0.42% +50.8% 6e-4 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 103 0.6% 38/65 0.00459/0.00765 +0.31% +40.0% 1e-2 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 91 0.5% 15/76 0.00181/0.00895 +0.71% +79.7% <1e-10 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 91 0.5% 14/77 0.00169/0.00906 +0.74% +81.3% <1e-10 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 90 0.5% 24/66 0.00290/0.00777 +0.49% +62.7% 2e-5 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 68 0.4% 14/54 0.00169/0.00636 +0.47% +73.4% 1e-6 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 68 0.4% 49/19 0.00592/0.00224 -0.37% -62.2% 2e-4 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 67 0.4% 35/32 0.00423/0.00377 -0.05% -10.9% 7e-1 10 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 65 0.4% 25/40 0.00302/0.00471 +0.17% +35.8% 8e-2 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 58 0.3% 8/50 0.00097/0.00589 +0.49% +83.6% 2e-8 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 57 0.3% 35/22 0.00423/0.00259 -0.16% -38.8% 8e-2 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 55 0.3% 23/32 0.00278/0.00377 +0.10% +26.2% 3e-1 5 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 50 0.3% 15/35 0.00181/0.00412 +0.23% +56.0% 7e-3 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 50 0.3% 19/31 0.00230/0.00365 +0.14% +37.1% 1e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 48 0.3% 5/43 0.00060/0.00506 +0.45% +88.1% 1e-8 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 48 0.3% 28/20 0.00338/0.00235 -0.10% -30.4% 2e-1 1 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 46 0.3% 16/30 0.00193/0.00353 +0.16% +45.3% 5e-2 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 45 0.3% 29/16 0.00350/0.00188 -0.16% -46.2% 5e-2 5 +[R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 40 0.2% 16/24 0.00193/0.00282 +0.09% +31.6% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 36 0.2% 15/21 0.00181/0.00247 +0.07% +26.7% 4e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 36 0.2% 24/12 0.00290/0.00141 -0.15% -51.3% 4e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 35 0.2% 24/11 0.00290/0.00129 -0.16% -55.3% 3e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 35 0.2% 16/19 0.00193/0.00224 +0.03% +13.6% 7e-1 1 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 35 0.2% 12/23 0.00145/0.00271 +0.13% +46.4% 9e-2 7 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 34 0.2% 22/12 0.00266/0.00141 -0.12% -46.9% 9e-2 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 32 0.2% 19/13 0.00230/0.00153 -0.08% -33.3% 3e-1 43 +[Q14K,Q52H,L455F,F456L] N/A 16773 32 0.2% 12/20 0.00145/0.00235 +0.09% +38.4% 2e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 32 0.2% 7/25 0.00085/0.00294 +0.21% +71.3% 2e-3 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 31 0.2% 23/8 0.00278/0.00094 -0.18% -66.1% 6e-3 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 31 0.2% 10/21 0.00121/0.00247 +0.13% +51.1% 7e-2 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 31 0.2% 30/1 0.00362/0.00012 -0.35% -96.8% 1e-8 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 29 0.2% 14/15 0.00169/0.00177 +0.01% +4.2% 1e+0 1 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 29 0.2% 18/11 0.00217/0.00129 -0.09% -40.5% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 29 0.2% 10/19 0.00121/0.00224 +0.10% +46.0% 1e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 28 0.2% 13/15 0.00157/0.00177 +0.02% +11.0% 9e-1 1 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 28 0.2% 22/6 0.00266/0.00071 -0.20% -73.4% 2e-3 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 27 0.2% 5/22 0.00060/0.00259 +0.20% +76.7% 2e-3 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 26 0.2% 3/23 0.00036/0.00271 +0.23% +86.6% 9e-5 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 26 0.2% 17/9 0.00205/0.00106 -0.10% -48.4% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 26 0.2% 10/16 0.00121/0.00188 +0.07% +35.8% 3e-1 2 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 24 0.1% 4/20 0.00048/0.00235 +0.19% +79.5% 2e-3 3 +[+16IPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 23 0.1% 15/8 0.00181/0.00094 -0.09% -48.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 22 0.1% 6/16 0.00072/0.00188 +0.12% +61.5% 5e-2 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 22 0.1% 8/14 0.00097/0.00165 +0.07% +41.3% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 22 0.1% 14/8 0.00169/0.00094 -0.07% -44.3% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 22 0.1% 5/17 0.00060/0.00200 +0.14% +69.8% 2e-2 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 21 0.1% 5/16 0.00060/0.00188 +0.13% +67.9% 3e-2 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 20 0.1% 3/17 0.00036/0.00200 +0.16% +81.9% 3e-3 5 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 20 0.1% 20/0 0.00242/0.00000 -0.24% -100.0% 7e-7 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 20 0.1% 8/12 0.00097/0.00141 +0.04% +31.6% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 20 0.1% 9/11 0.00109/0.00129 +0.02% +16.0% 8e-1 2 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 19 0.1% 12/7 0.00145/0.00082 -0.06% -43.2% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 18 0.1% 9/9 0.00109/0.00106 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 18 0.1% 16/2 0.00193/0.00024 -0.17% -87.8% 6e-4 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 18 0.1% 11/7 0.00133/0.00082 -0.05% -38.0% 4e-1 2 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 18 0.1% 12/6 0.00145/0.00071 -0.07% -51.3% 2e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 17 0.1% 12/5 0.00145/0.00059 -0.09% -59.4% 9e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 17 0.1% 6/11 0.00072/0.00129 +0.06% +44.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 17 0.1% 3/14 0.00036/0.00165 +0.13% +78.0% 1e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T732I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 17 0.1% 5/12 0.00060/0.00141 +0.08% +57.2% 1e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 17 0.1% 14/3 0.00169/0.00035 -0.13% -79.1% 7e-3 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 17 0.1% 10/7 0.00121/0.00082 -0.04% -31.8% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 16 0.1% 5/11 0.00060/0.00129 +0.07% +53.3% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V407I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 16 0.1% 2/14 0.00024/0.00165 +0.14% +85.3% 4e-3 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 16 0.1% 12/4 0.00145/0.00047 -0.10% -67.5% 5e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 16 0.1% 9/7 0.00109/0.00082 -0.03% -24.2% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 16 0.1% 9/7 0.00109/0.00082 -0.03% -24.2% 6e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 15 0.1% 6/9 0.00072/0.00106 +0.03% +31.6% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 15 0.1% 3/12 0.00036/0.00141 +0.10% +74.3% 4e-2 3 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 15 0.1% 4/11 0.00048/0.00129 +0.08% +62.7% 1e-1 5 +[R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 14 0.1% 6/8 0.00072/0.00094 +0.02% +23.0% 8e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 14 0.1% 5/9 0.00060/0.00106 +0.05% +43.0% 4e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 14 0.1% 10/4 0.00121/0.00047 -0.07% -61.0% 1e-1 45 +[Q52H,+214YRR,N450D,L455F,F456L,S704L] N/A 16773 13 0.1% 4/9 0.00048/0.00106 +0.06% +54.4% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N960S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 13 0.1% 4/9 0.00048/0.00106 +0.06% +54.4% 3e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 13 0.1% 2/11 0.00024/0.00129 +0.11% +81.3% 2e-2 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 13 0.1% 9/4 0.00109/0.00047 -0.06% -56.7% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 13 0.1% 2/11 0.00024/0.00129 +0.11% +81.3% 2e-2 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 10/2 0.00121/0.00024 -0.10% -80.5% 2e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 9/3 0.00109/0.00035 -0.07% -67.5% 9e-2 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 5/7 0.00060/0.00082 +0.02% +26.7% 8e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 9/3 0.00109/0.00035 -0.07% -67.5% 9e-2 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 5/7 0.00060/0.00082 +0.02% +26.7% 8e-1 5 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 2/10 0.00024/0.00118 +0.09% +79.5% 4e-2 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1244F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 4/8 0.00048/0.00094 +0.05% +48.7% 4e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 0/12 0.00000/0.00141 +0.14% +100.0% 5e-4 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,A288T,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 6/6 0.00072/0.00071 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 7/5 0.00085/0.00059 -0.03% -30.4% 6e-1 2 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 12 0.1% 8/4 0.00097/0.00047 -0.05% -51.3% 3e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 5/6 0.00060/0.00071 +0.01% +14.5% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 6/5 0.00072/0.00059 -0.01% -18.8% 8e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 3/8 0.00036/0.00094 +0.06% +61.5% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 0/11 0.00000/0.00129 +0.13% +100.0% 1e-3 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 7/4 0.00085/0.00047 -0.04% -44.3% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 11 0.1% 3/8 0.00036/0.00094 +0.06% +61.5% 2e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 7/4 0.00085/0.00047 -0.04% -44.3% 4e-1 5 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 0/11 0.00000/0.00129 +0.13% +100.0% 1e-3 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 4/7 0.00048/0.00082 +0.03% +41.3% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 11/0 0.00133/0.00000 -0.13% -100.0% 4e-4 42 +[Q52H,L455F,F456L] N/A 16773 11 0.1% 6/5 0.00072/0.00059 -0.01% -18.8% 8e-1 42 +[Q52H,N450D,L455F,F456L,S704L] N/A 16773 11 0.1% 9/2 0.00109/0.00024 -0.09% -78.4% 4e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 1/10 0.00012/0.00118 +0.11% +89.7% 1e-2 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 11 0.1% 10/1 0.00121/0.00012 -0.11% -90.3% 6e-3 2 +[+16IPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 2/8 0.00024/0.00094 +0.07% +74.3% 1e-1 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 4/6 0.00048/0.00071 +0.02% +31.6% 8e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 8/2 0.00097/0.00024 -0.07% -75.6% 6e-2 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 4/6 0.00048/0.00071 +0.02% +31.6% 8e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 1/9 0.00012/0.00106 +0.09% +88.6% 2e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,K558N,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 3/7 0.00036/0.00082 +0.05% +56.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 2/8 0.00024/0.00094 +0.07% +74.3% 1e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 3/7 0.00036/0.00082 +0.05% +56.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 6/4 0.00072/0.00047 -0.03% -35.1% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 10/0 0.00121/0.00000 -0.12% -100.0% 9e-4 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 7/3 0.00085/0.00035 -0.05% -58.2% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 10 0.1% 9/1 0.00109/0.00012 -0.10% -89.2% 1e-2 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 0/9 0.00000/0.00106 +0.11% +100.0% 4e-3 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L,D1168G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 4/5 0.00048/0.00059 +0.01% +17.9% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 2/7 0.00024/0.00082 +0.06% +70.7% 2e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 0/9 0.00000/0.00106 +0.11% +100.0% 4e-3 3 +[+16MPLF,R21T,S50L,H69-,V70-,G72W,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 6/3 0.00072/0.00035 -0.04% -51.3% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 6/3 0.00072/0.00035 -0.04% -51.3% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 7/2 0.00085/0.00024 -0.06% -72.2% 1e-1 6 +[R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 6/3 0.00072/0.00035 -0.04% -51.3% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 7/2 0.00085/0.00024 -0.06% -72.2% 1e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 9 0.1% 8/1 0.00097/0.00012 -0.08% -87.8% 2e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,V534I,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 1/7 0.00012/0.00082 +0.07% +85.3% 7e-2 9 +[R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 2/6 0.00024/0.00071 +0.05% +65.8% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K304N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 1/7 0.00012/0.00082 +0.07% +85.3% 7e-2 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N137K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 5/3 0.00060/0.00035 -0.03% -41.5% 5e-1 5 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 0/8 0.00000/0.00094 +0.09% +100.0% 8e-3 6 +[R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 0/8 0.00000/0.00094 +0.09% +100.0% 8e-3 3 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 2/6 0.00024/0.00071 +0.05% +65.8% 3e-1 1 +[+16MPLF,R21T,S50L,S60F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 1/7 0.00012/0.00082 +0.07% +85.3% 7e-2 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 7/1 0.00085/0.00012 -0.07% -86.1% 4e-2 43 +[Q52H,L455F,F456L,I1114T] N/A 16773 8 0.0% 6/2 0.00072/0.00024 -0.05% -67.5% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 1/7 0.00012/0.00082 +0.07% +85.3% 7e-2 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 8/0 0.00097/0.00000 -0.10% -100.0% 4e-3 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 8 0.0% 3/5 0.00036/0.00059 +0.02% +38.4% 7e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 5/2 0.00060/0.00024 -0.04% -61.0% 3e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 7 0.0% 2/5 0.00024/0.00059 +0.03% +58.9% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,R567K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 0/7 0.00000/0.00082 +0.08% +100.0% 2e-2 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 7 0.0% 0/7 0.00000/0.00082 +0.08% +100.0% 2e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 3/4 0.00036/0.00047 +0.01% +23.0% 1e+0 7 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 5/2 0.00060/0.00024 -0.04% -61.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V642F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 4/3 0.00048/0.00035 -0.01% -26.9% 7e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 5/2 0.00060/0.00024 -0.04% -61.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 7/0 0.00085/0.00000 -0.08% -100.0% 7e-3 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K964R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 5/2 0.00060/0.00024 -0.04% -61.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 6/1 0.00072/0.00012 -0.06% -83.8% 7e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 1/6 0.00012/0.00071 +0.06% +82.9% 1e-1 14 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 7 0.0% 6/1 0.00072/0.00012 -0.06% -83.8% 7e-2 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 5/1 0.00060/0.00012 -0.05% -80.5% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 4/2 0.00048/0.00024 -0.02% -51.3% 4e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 0/6 0.00000/0.00071 +0.07% +100.0% 3e-2 3 +[+16MPLF,R21T,S50L,Q52K,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 2/4 0.00024/0.00047 +0.02% +48.7% 7e-1 5 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 2/4 0.00024/0.00047 +0.02% +48.7% 7e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 6 0.0% 1/5 0.00012/0.00059 +0.05% +79.5% 2e-1 8 +[R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 1/5 0.00012/0.00059 +0.05% +79.5% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,S94F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,R567K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 4/2 0.00048/0.00024 -0.02% -51.3% 4e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 5/1 0.00060/0.00012 -0.05% -80.5% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 6/0 0.00072/0.00000 -0.07% -100.0% 1e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 2/4 0.00024/0.00047 +0.02% +48.7% 7e-1 3 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 6/0 0.00072/0.00000 -0.07% -100.0% 1e-2 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 4/2 0.00048/0.00024 -0.02% -51.3% 4e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 6 0.0% 1/5 0.00012/0.00059 +0.05% +79.5% 2e-1 7 +[R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 6 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 4/2 0.00048/0.00024 -0.02% -51.3% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A846V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 0/6 0.00000/0.00071 +0.07% +100.0% 3e-2 12 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 12 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 5/1 0.00060/0.00012 -0.05% -80.5% 1e-1 48 +[Q14K,+17S,T20-,Q52H,L455F,F456L,T588I,G946R]-[T19I] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 8 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 6 +[R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 2/4 0.00024/0.00047 +0.02% +48.7% 7e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 6 0.0% 2/4 0.00024/0.00047 +0.02% +48.7% 7e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 3/3 0.00036/0.00035 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,P57S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 0/6 0.00000/0.00071 +0.07% +100.0% 3e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1177L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 0/6 0.00000/0.00071 +0.07% +100.0% 3e-2 6 +[R21T,S50L,I68M,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 6 0.0% 2/4 0.00024/0.00047 +0.02% +48.7% 7e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 0/5 0.00000/0.00059 +0.06% +100.0% 6e-2 5 +[+16MPLF,R21T,S31-,R34C,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 0/5 0.00000/0.00059 +0.06% +100.0% 6e-2 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 1 +[+16MPLF,R21T,G35S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 0/5 0.00000/0.00059 +0.06% +100.0% 6e-2 3 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 4/1 0.00048/0.00012 -0.04% -75.6% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S640F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 1/4 0.00012/0.00047 +0.03% +74.3% 4e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 5 0.0% 3/2 0.00036/0.00024 -0.01% -35.1% 7e-1 3 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 3/2 0.00036/0.00024 -0.01% -35.1% 7e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 1/4 0.00012/0.00047 +0.03% +74.3% 4e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,A575S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 1/4 0.00012/0.00047 +0.03% +74.3% 4e-1 7 +[R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 0/5 0.00000/0.00059 +0.06% +100.0% 6e-2 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,I670M,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 3/2 0.00036/0.00024 -0.01% -35.1% 7e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,+209V,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 5 0.0% 3/2 0.00036/0.00024 -0.01% -35.1% 7e-1 1 +[+16MPLF,R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 1/4 0.00012/0.00047 +0.03% +74.3% 4e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 5 0.0% 4/1 0.00048/0.00012 -0.04% -75.6% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,P521S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 5/0 0.00060/0.00000 -0.06% -100.0% 3e-2 43 +[Q14H,Q52H,L455F,F456L] N/A 16773 5 0.0% 3/2 0.00036/0.00024 -0.01% -35.1% 7e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 1/4 0.00012/0.00047 +0.03% +74.3% 4e-1 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1129I,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 3/2 0.00036/0.00024 -0.01% -35.1% 7e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,P85S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 5/0 0.00060/0.00000 -0.06% -100.0% 3e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1182Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 1/4 0.00012/0.00047 +0.03% +74.3% 4e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 3/2 0.00036/0.00024 -0.01% -35.1% 7e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1170T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 6 +[R21T,S50L,H69-,V70-,D88G,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 4/1 0.00048/0.00012 -0.04% -75.6% 2e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 4/1 0.00048/0.00012 -0.04% -75.6% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N282S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 0/5 0.00000/0.00059 +0.06% +100.0% 6e-2 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,G257R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 0/5 0.00000/0.00059 +0.06% +100.0% 6e-2 48 +[A27-,Q52H,+214YRR,N450D,L455F,F456L,S704L,D936Y]-[L24-,A27S] N/A 16773 5 0.0% 1/4 0.00012/0.00047 +0.03% +74.3% 4e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 4/1 0.00048/0.00012 -0.04% -75.6% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 1/4 0.00012/0.00047 +0.03% +74.3% 4e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,F565L,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 4/1 0.00048/0.00012 -0.04% -75.6% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 5/0 0.00060/0.00000 -0.06% -100.0% 3e-2 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 3/2 0.00036/0.00024 -0.01% -35.1% 7e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 5/0 0.00060/0.00000 -0.06% -100.0% 3e-2 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261-,+264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 5/0 0.00060/0.00000 -0.06% -100.0% 3e-2 2 +[+16MPLF,R21T,S50L,H69-,V70-,A123V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,G842S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 3/2 0.00036/0.00024 -0.01% -35.1% 7e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 4/1 0.00048/0.00012 -0.04% -75.6% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A942S,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 2/3 0.00024/0.00035 +0.01% +31.6% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,I624V,P681R,S939F,P1143L,L1186I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 0/5 0.00000/0.00059 +0.06% +100.0% 6e-2 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 0/5 0.00000/0.00059 +0.06% +100.0% 6e-2 7 +[R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 5 0.0% 0/5 0.00000/0.00059 +0.06% +100.0% 6e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 5 0.0% 5/0 0.00060/0.00000 -0.06% -100.0% 3e-2 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 4/0 0.00048/0.00000 -0.05% -100.0% 6e-2 6 +[R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 5 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,G639S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,I1183V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 4 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,L249F,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E654V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 3 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1176F,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T961M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 4/0 0.00048/0.00000 -0.05% -100.0% 6e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 2 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P812L,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 4/0 0.00048/0.00000 -0.05% -100.0% 6e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478R,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 4 0.0% 4/0 0.00048/0.00000 -0.05% -100.0% 6e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 4/0 0.00048/0.00000 -0.05% -100.0% 6e-2 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,T208M,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 1 +[F2L,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 1 +[+16LPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T638K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 4/0 0.00048/0.00000 -0.05% -100.0% 6e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,G482S,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 4/0 0.00048/0.00000 -0.05% -100.0% 6e-2 6 +[R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N282S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N960S,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 4 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,R190K,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 7 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 7 +[R21T,S50L,Q52K,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 1/3 0.00012/0.00035 +0.02% +65.8% 6e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547I,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 2/2 0.00024/0.00024 -0.00% -2.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 3/1 0.00036/0.00012 -0.02% -67.5% 4e-1 6 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 4/0 0.00048/0.00000 -0.05% -100.0% 6e-2 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N641T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 4 0.0% 0/4 0.00000/0.00047 +0.05% +100.0% 1e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 5 +[R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V407I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445Y,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 1 +[+16VPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1219C]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 4 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 5 +[+16MPLF,R21T,S50L,H69S,S71-,G72-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,K558N,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323K,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V407I,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,T961M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,D88G,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 5 +[R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 43 +[Q52H,K356T,R408G,L455F,F456L,N703I]-[R408S] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 8 +[R21T,S31F,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 4 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,V642A,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,Q613H,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S50L,S60A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[L8M,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V642G,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K147E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,D111N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 49 +[K77R,N148T,N185I,F186-,D253G,+374F,T376-,P521S]-[G252V,S375F,T376A,T478K] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 44 +[Q52H,L176F,L455F,F456L,I1114T] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 43 +[Q52H,L455F,F456L,A475V] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 8 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,L118F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 44 +[Q14R,T20N,Q52H,L455F,F456L] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A942S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,S60A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,N487D,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,Q954L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,K97N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1205R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16IPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,T29N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,N487D,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 6 +[R21T,S50L,S60P,H69-,V70-,V127F,K150T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,G482-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1181I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1265F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 2 +[+16MPLF,R21-,+22I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,L176F,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 4 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,G482D,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S939F,P1143L,N1178S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[S12A,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 3 +[+16MPLF,R21T,N30I,S31-,F32-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1070V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P793S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,T95S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 44 +[Q14K,Q52H,K182E,L455F,F456L] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 57 +[L48V,A67V,H69-,V70-,N74T,V90F,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,Q493R,G496S,T547K,N856K,L981F,I1179S]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,D405N,R408S,V445P,N460K,F486P,F490S] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,I569V,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 43 +[Q14R,Q52H,L455F,F456L] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K147N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N978T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q628H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,G482D,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 24 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,+363TRISNCVATRISNCVATRISNCV,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,A123S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N641S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 44 +[Q14K,Q52H,N185S,L455F,F456L] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1170P]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 1/2 0.00012/0.00024 +0.01% +48.7% 1e+0 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 0/3 0.00000/0.00035 +0.04% +100.0% 3e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 2/1 0.00024/0.00012 -0.01% -51.3% 6e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S373P,V445P,E484A,F490S,P681H] N/A 16773 3 0.0% 3/0 0.00036/0.00000 -0.04% -100.0% 1e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1232T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T500A,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V407I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 44 +[Q14K,Q52H,L455F,F456L,A475V] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q836L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,T250I,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,E1195D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,T33I,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,T547K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,H1159R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,R408G,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V382L,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1178D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T286I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A879V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,A93T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N137D,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,E780Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I834V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1178D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P809S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,A672V,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1191N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,P209H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1122L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,I624F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[R21-,+22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A520S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N658S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,D53E,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S929T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,G72W,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S929T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,+374F,T376-,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1199N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,V289I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[+16MPLF,R21-,+22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,A288T,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y144N,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529N,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1169M]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Y1110H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,T299I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P793T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,T208M,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,T33I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529N,E554K,A570V,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P812L,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16IPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680T,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,L1200F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 44 +[Q14K,Q52H,L455F,F456L,S704L] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,P809S,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255-,S256-,G257-,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,A647V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,Q52H,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 14 +[N17M,+17P,+18FNFI,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F175L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,G504D,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V382L,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 45 +[Q14K,Q52H,G181R,L455F,F456L,V1122L] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,E340K,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,D215Y,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 44 +[Q52R,K182N,D253G,N450D,T478R,P521S,E554K,V1122A,D1163G]-[G252V,T478K] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 50 +[Q52R,K182N,L241-,L242-,A243-,L244-,H245-,R246-,S247-,D253G,N450D,T478R,P521S,E554K,V1122A,D1163G]-[G252V,T478K] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A520S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 11 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,N679K,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,A1087S,P1143L,E1182Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 15 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,A1087S,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 44 +[Q14K,Q52H,G184A,L455F,F456L] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 43 +[Q14K,Q52H,H146K,L455F,F456L]-[H146Q] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,Q321R,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1244F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,G75V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T883I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250I,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MSLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1182Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1122L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554R,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1251A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y144N,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 46 +[N148T,N185I,F186-,D253G,T478R,P521S,N540S]-[G252V,T478K] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P793Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 46 +[Q14K,Q52H,N185D,L455F,F456L,A475V,D1259Y] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1099D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 11 +[S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 44 +[T478R,Q613H,A688V,K947R]-[T478K] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 9 +[R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,L84I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,Q321L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A846V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V976I,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,N606K,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,Q271K,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,S60A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I834V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A352S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 38 +[H69-,V70-,V213G,H245Y,G339D,N343S,K417D,K444T,L452R,F486V,A653V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 46 +[N148T,N185I,F186-,D253G,R408N,T478R,P521S]-[G252V,R408S,T478K] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,K150T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,S60F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455A,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T500A,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 4 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[R21T,S50L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1129I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237M,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T286R,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S640F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1181R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,A288S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385N,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,N710S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,G75R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1116N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 12 +[N17M,+17P,+18FNFI,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,T676I,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,Q613H,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,T95S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1122L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376V,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1262A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,G639D,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252D,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1168E]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1070V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 50 +[K77R,H146-,N148T,N185I,F186-,D253G,+374F,T376-,P521S,Q1201K]-[H146Q,G252V,S375F,T376A,T478K] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 7 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 8 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680-,+683R,S939F,K1086R,V1104L,P1143L,K1245R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E661D,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,F565L,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A879S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,A123V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684T,G842S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T859I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,G1099S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1249F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478R,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 7 +[R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I692F,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 44 +[Q52H,Y248H,N450D,L455F,F456L,S704L,V1176F] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,D178N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[P25-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A879S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,F306L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N148T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181A,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 6 +[R21-,+22I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 7 +[R21T,S50L,H69-,V70-,P82T,V127F,M153V,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,E180V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1181R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A892V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150R,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L242F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S637F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V622I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1216V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1124S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,S162I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 42 +[Q52H,G142Y,F456L,E484K]-[G142D,E484A] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,F55Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 4 +[+16MPLF,R21T,S50L,T51I,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,R1014S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211I,L212G,V213H,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 6 +[R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T573I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[L8M,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1158S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,T883I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,T1116N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,R78M,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,L841R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21T,S50L,A67S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 9 +[R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 9 +[R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 8 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,K854N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,D215G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,A1174V]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q779K,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[F4S,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1260N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,M177I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T874I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,H49Y,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A831V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[R21T,S50L,H69-,V70-,T73I,V127F,D138H,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 6 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 8 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,H625Q,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N641S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[Q14L,C15F,V16-,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A879S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547I,E554K,A570V,P621S,P681R,S939F,T1116N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554N,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[R21T,S50L,I68-,H69-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,K150R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683W,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 13 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S982A,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 11 +[S50L,H69-,V70-,V127F,K147E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 13 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L179I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 43 +[Y248H,L455F,F456L,A475V] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1020V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 43 +[V3G,L5F,H69-,V70-,F157L,G181V,V213G,R214H,T299I,G339D,K444N,L452R,E484V,F486V,G504S,G593S,H625L,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,F1103L,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,I410V,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 2 +[+16MPLF,R21T,S50L,S60F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,W152R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 8 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211I,+211G,V213-,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1210T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V642I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 2 +[+16MPLF,R21T,T29I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,+374F,T376-,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1073N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 5 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,Q173R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,N137K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 1/1 0.00012/0.00012 -0.00% -2.6% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,N137K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I726V,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1200I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 2/0 0.00024/0.00000 -0.02% -100.0% 2e-1 2 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1232T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A701V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S704L,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 5 +[+16MPLF,R21-,+22I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[R21T,T33I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 3 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1122L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 7 +[R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 8 +[R21-,+22N,S50L,F58L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 6 +[R21T,S50L,S60A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 8 +[R21T,S50L,F59S,H69-,V70-,N87K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 2 0.0% 0/2 0.00000/0.00024 +0.02% +100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[Q52H,V227L,L455F,F456L,S704L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,E654Q,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R765L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L,V1189A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,Q677R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522S,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V407I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,T124S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L179F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,P479L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16CL,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,Y421H,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A831V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,P82L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,L118F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1163Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1259Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[S13T,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547I,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,A123V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,L249F,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211M,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,P384H,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L,D1168G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,P561H,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683Q,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1122L,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,T547I,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A522V,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,I670T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A831V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,L461I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,N30H,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,R246I,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P812S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,A27-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V622I,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,D389N,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T724S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L,E1202G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,S60A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A846S,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,D287E,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N280S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1201H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,R567K,A570V,P621S,S640Y,N641-,P681R,S939F,P1143L,D1153N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,D111N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P631S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,G184D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q836L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S31Y,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R765C,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I844V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680-,+683R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D1257E]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 47 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,N30T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,H69-,V70-,V127F,K150Q,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[V3I,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1170P]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,S477D,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478R,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21-,+22N,S50L,F58L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16IPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,N149-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K986R,P1143L,E1150D,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69A,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D796H,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,K529T,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K947R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,+374F,T376-,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q675H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254Y,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S31F,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,Y279H,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444N,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1170T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,W152L,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688T,S689I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T778I,S939F,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1146Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,A475V,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211I,L212R,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,N87K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y145L,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1124V,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,F592S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,D53E,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N540H,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,I402V,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,I402V,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,L518Q,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157L,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,F592S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S375-,T376-,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I923V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,L582F,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1163G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,N148T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1202V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S659L,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,R78K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,C1248R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,L1224S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S31-,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,K147N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,P82S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258R,A264D,I332V,K356T,R403K,D405Y,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,D405N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T274A,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S673T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,E154Q,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S31F,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,G504S,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 12 +[R21T,F32L,S50L,F59I,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,V1104L,P1143L,E1144Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,M177I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,T33I,S50L,H69-,V70-,V127F,Y144N,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,P272H,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1183L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P793S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1260A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,L249F,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,L293F,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P793S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1022V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253E,A264D,I332V,K356T,R403K,N440R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,V143F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,L84Q,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,+186DRG,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1251A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,A575S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T259A,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,A575S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,Q613E,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[L5F,R21T,S50L,S60P,H69-,V70-,V127F,S151G,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1170F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,A626V,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K300M,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,G35S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,T76I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445Y,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,G476-,T478N,+478K,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69A,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1181I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D820N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,P39H,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q14K,Q52H,L455F,F456L,A520T] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16VPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1120S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,L118F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1189A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1253W]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,G75A,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[F4L,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,V47F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[S13T,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211M,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,T547I,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,K150N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1224F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T732I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,N556S,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,L1265F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,G446I,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1040A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,D111N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483T,E484-,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,L84T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1094I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,V1177L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,G268D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,N30T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A701V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[V3A,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,E583D,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,G1099D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,R190K,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A706V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16KPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K417Y,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445L,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,G594S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[V11-,S12-,S13-,Q14-,C15-,V16-,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,N30K,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,N824Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,K854E,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,V47A,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,H1159R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S750N,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,Y269F,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A892V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,N30Y,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q690R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A520S,E554K,A570V,P621S,P681R,S939F,I1115V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 38 +[S31F,H69-,V70-,V213G,G257S,G339D,K444T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I805M,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 46 +[Q52H,V143D,Y144Q,Y145-,H146-,L455F,F456L,I1114T]-[Y144-,H146Q] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1265F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 43 +[Q52H,F456L,F490P,Q493L]-[F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,M177I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,V42F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529N,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 37 +[S31F,H69-,V70-,V213G,G339D,K444T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,K558N,A570V,P621S,Q677L,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K947I,P1143L,G1251V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T553S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,S514F,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,F1103L,P1143L,G1251V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,G482S,V483-,E484K,E554K,A570V,P621S,T678-,+679K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 50 +[K77R,N148T,N185I,F186-,D253G,+374F,T376-,P521S,D1153Y]-[G252V,S375F,T376A,T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,G75V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,N679R,P681R,S939F,V1133I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,K147R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T883M,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,D936N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181A,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403N,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N960K,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,K77N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,E132Q,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,E340Q,K356T,V367A,T385I,R403K,V445H,N450D,L452W,K462E,N481K,V483-,E484K,N487D,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,P792Q,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S46A,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,R683Q,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V705F,D796H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679T,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 46 +[Q14K,Q52H,G181R,L455F,F456L,H1058Y,V1122L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 64 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P681R,S939F,A1070T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T573I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T573I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,T547K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,F338L,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,H519Y,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T961M,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I934V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1260H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,W152R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 50 +[K77R,N148T,N185I,F186-,D253G,+374F,T376-,K444R,P521S]-[G252V,S375F,T376A,T478K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,T676S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,S162N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q675K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S640F,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,I1169V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K304Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,F65S,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,A575S,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 43 +[Q52H,L455F,F456L,S704L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S247I,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[R21T,S31F,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1038R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,N856S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,N334K,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,D1127A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q173H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 43 +[Q52H,L455F,F456L,T572I] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q52H,F157L,E340Q,L452R,F456L,T572I] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T961A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,A701V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MSLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A846V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,E156D,F157-,R158-,V159-,Y160-,S161-,S162-,A163-,N164-,N165-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A852T,S939F,P1143L,I1179T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,I670V,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N501Y,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 12 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 12 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,W64R,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683Q,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 13 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21-,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 45 +[I434M,F456L,T478R,A701V,T883I]-[T478K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,V445P,N460K,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323A,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483T,E484-,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 13 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S371F,S373P,S375F,T376A,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339R,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,D1084E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1120I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 13 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,P384S,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 46 +[M153I,F186S,Y200C,S247N,T478R,E554Q,T572I]-[T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 12 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T961M,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 13 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[E180V,T478R,Q613H,Q675K,V1230A]-[T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P330S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T747I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[+16MPLF,S50L,H69-,V70-,V127F,K147T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T883M,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[N148T,Q218R,Y248F,D253G,N450D,F456L,S494P,P521S,P1143S]-[G252V] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D796H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,A475S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,G381R,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,A67F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A831V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,T286I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 14 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,F400S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,D405N,R408S,K417N,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 13 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K356T,V445H,N450D,L452W,L455S,A475V,N481K,V483T,E484-,E554K,A570V,P621S,S939F,P1143L]-[V83A,Q183E,V213E,R408S,V445P,N460K,E484A] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483T,E484-,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184V,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,K77N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,K147N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1261P]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254Y,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,Q954Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,L176F,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1244F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 10 +[R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T618S,P621S,P681R,T747A,Q774R,S939F,N1108S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1114S,P1143L,D1257E]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,L56F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N1125S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1265F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,T29-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,P384S,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 10 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,M177-,D178-,L179-,E180-,G181-,K182-,Q183-,G184-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1224V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[V6A,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1020V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,A668S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1254F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,G476-,T478N,+478K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211I,+211G,V213-,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S875A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,P479L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,K77N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[S12F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21-,+22I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D796H,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,T76I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1201H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478Q,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1168H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69P,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,I105L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[Q14L,C15F,V16-,R21T,S50L,H69-,V70-,V127F,S151C,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A348V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,R1185H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,R408G,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1016V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L,M1229I,D1260N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D936E,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 12 +[S50L,H69-,V70-,V127F,F157S,R158G,H207Y,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 11 +[L5F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 14 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V367I,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,K854N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1020S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,R34C,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,A626V,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252D,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,T768I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16M,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21I,S50L,L56S,H69-,V70-,N87K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1259Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E324A,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T883I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 11 +[S50L,H69-,V70-,F106L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,W64R,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 11 +[S50L,H69-,V70-,V127F,K150I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1072D,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 12 +[S50L,H69-,V70-,V127F,F157S,R158G,G181R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688D,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,V127F,K147T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 11 +[T33I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,A288V,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,A623-,I624-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T523N,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A899S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I834V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 10 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S375-,T376-,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A522S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,A123S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[L5F,R21T,T33S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S640Y,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 46 +[Q52H,I402T,L455F,F456L,S704L,L981I,S1242C] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S939F,P1143L,N1178S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N641I,V642-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,A93S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N658K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218E,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,T76A,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1202K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,R78M,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A942S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A344S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,T29N,G35R,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445Q,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L226V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,H625R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,F55L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,P479L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A1070V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,V36F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,Y28H,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 10 +[R21T,S50L,H69-,V70-,V127F,K150I,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I693V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T961M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 13 +[N17M,+17P,+18FNFI,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,G1099S,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S735A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 33 +[Q14K,Q52H,H146K,L452W,N481K,V483-,E484K,P621S,P681R,S939F,P1143L]-[H146Q,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V120I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1265F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 14 +[R21T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,P621S,P681R,S939F,P1143L]-[Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 43 +[Q52H,D138H,L455F,F456L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253Y,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[C15F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I794T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,R1185S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,I105V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,A626S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,E619V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621F,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1177L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,G946V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185-,F186-,K187-,N188-,L189-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,T29N,V47A,S50L,H69-,V70-,V127F,F157S,R158G,S172F,T208A,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,R78M,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T859A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,+215F,P217-,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,K790I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S375-,T376-,F377-,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 18 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K356T,N481K,V483-,E484K,E554K,A570V,P621S,S939F,T1076I,V1104L,P1143L]-[H146Q,Q183E,V213E,R408S,K417N,N440K,V445P,G446S,N460K,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 21 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N481K,V483-,E484K,E554K,A570V,P621S,S939F,T1076I,P1143L]-[V83A,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S1021F,P1143L,I1232T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T500A,E554K,A570V,P621S,P681R,S939F,L1034F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S31F,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,+209V,N211G,L212-,V213-,L216F,G219D,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529N,E554K,A570V,P621S,P681R,S939F,G946V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,+215F,P217-,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Y170H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,P272H,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[S256L,T259I,L455F,F456L,A475V] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,Q474K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211I,L212G,V213H,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,R567K,A570V,P621S,N679T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,S459Y,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A924V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,K150E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445Y,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D936Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MLF,R21T,S50L,H69-,V70-,V127F,E132K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 43 +[Q52H,F456L,F1220C] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,A67S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D867G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 41 +[K147E,F157L,+209V,N211G,L212-,V213-,G257S,A288V,K356T,S735L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 41 +[Q14K,Q52H,L216F,L455F,F456L,E554K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[P25-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16IPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478R,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 40 +[F456L,N481K,F490P,P681R,A701V]-[F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Q,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445Y,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1200F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445Y,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,V62I,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 42 +[Q173K,L335S,R403K,T478R]-[T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T573I,P621F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S31F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,I105V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,I100L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,E154K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T274I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,S943G,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q52H,F157L,F456L,T572I,S691F,D950E]-[F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,K529N,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,D627H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237M,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,D405N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,S477K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,D138G,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1070S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,P230S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1133I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,V36F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,+482K,E484P,G485-,F486-,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127L,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S640Y,N641-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237M,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S371F,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,G932S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S31P,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N501Y,Y505H,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N501Y,Y505H,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,L249W,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P792S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,Y28H,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478Q,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1168N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[F2L,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,F486S,E554K,A570V,P621S,P681R,S939F,P1143L,S1196Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529N,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,A67S,I68T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,W886L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,G1085R,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K537R,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1259Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,D627N,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,D88G,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 45 +[Q52H,T76A,T323I,F456L,A653V] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339Y,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D936Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I794T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1077A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K964R,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,T76-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 42 +[Q52H,H69-,V70-,L335F,L455F,F456L,C1236F] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,P479H,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q173K,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,P85L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,Y91F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Y1155H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 21 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,+186NVAH,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,E554K,A570V,P621S,S939F,T1076I,P1143L]-[H146Q,Q183E,V213E,L368I,D405N,R408S,K417N,N440K,V445P,G446S,N460K,E484A,F490S,N764K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1248Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T470I,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,N717S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,L822F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339Y,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A344S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,S940F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,K417S,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T961M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,Q173H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N1134K,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1179V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,T676I,P681R,P812L,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,W152R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,F306L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S884F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,S155I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,I68T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I818V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V785I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[P25-,A27S,V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,T33A,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,G75A,V127F,F157S,R158G,M177I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,F186S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255P,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1219V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[F2L,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,G142N,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621F,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1116N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L179F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L,D1168G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478Q,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,Q493L,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,A123S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q675K,P681R,S939F,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A942S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,G35R,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A352S,K356T,R403K,V445H,G446N,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,Q134H,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,D1127E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[L8M,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1191N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A893P,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1233L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,M177T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[F2L,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,T723I,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,L56V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,D287G,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q836L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I834V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1079S,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T791I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,P337S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483T,E484-,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 10 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,L368I,N440K,V445P,G446S,N460K,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 20 +[+16MPLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,G416E,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 18 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69-,V70-,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,M697L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A942V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A344V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1179V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,I569V,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,K77E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,D405N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,P561H,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 20 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,A475V,N481K,V483T,E484-,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,R408S,K417N,N440K,V445P,G446S,N460K,E484A] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,Q498R,N501Y,Y505H,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F464L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,D405N,R408S,K417N,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 12 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483T,E484-,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,L368I,N440K,V445P,G446S,N460K,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,V445P,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483T,E484-,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,V445P,E484A] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[V16F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1080S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S698L,A706V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[L5F,P9L,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,M740T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,K150E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,Y37H,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q52H,F157L,L452W,F456L,T547K,G1124V]-[R408S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339R,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L,E1195Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L242P,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,V503I,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16IPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153V,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 54 +[K77R,V143D,Y144Q,Y145-,H146-,N148T,D178N,N185I,F186-,D253G,A372V,+374F,T376-,P521S]-[Y144-,H146Q,G252V,S375F,T376A,T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1171D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T470I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,R1185S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I834V,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 10 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,D405N,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 42 +[F456L,T478R,N481K,F490P,P681R,A701V,T761A]-[T478K,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1078V,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1247Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16LPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,S443A,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S943G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,S60P,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,G476-,T478N,+478K,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V90F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Q498R,N501Y,Y505H,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 46 +[Q14K,Q52H,L455F,F456L,F486L,G946R,T1116S]-[F486P] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[Y145P,H146-,I210-,F456L,F486S]-[Y144-,H146Q,F486P] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445Y,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S929T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,T33S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1259Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,S60A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845D,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 50 +[K77R,N148T,N185I,F186-,D253V,+374F,T376-,P521S,T739A]-[G252V,S375F,T376A,T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 11 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1237V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684V,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1195G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,N603S,P621S,N641K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q779K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S750N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346G,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,K825E,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69P,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,+18V,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V622I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,K462E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V83F,A123S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[+16MPLF,R21T,S50L,H69P,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,+482K,E484P,G485-,F486-,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,F1103L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,K182Q,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[S12Y,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D820N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554T,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1223S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q779H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,D178N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251T,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[Q14K,Q52H,F186L,L455F,F456L,T478R]-[T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 46 +[Q14K,Q52H,N185D,L293F,L455F,F456L,A475V] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 47 +[Q14K,Q52H,G219S,S375-,T376-,F377-,L455F,F456L]-[S375F,T376A] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 32 +[Q14K,Q52H,G219S,K356T,V445H,N450D,L455F,F456L,N481K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L368I,V445P,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 37 +[Q52H,H146K,I332V,K356T,L455F,F456L,P681R]-[H146Q,R346T,L368I,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A829T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486S,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1228L,V1230L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[L8F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 68 +[P9L,A67V,H69-,V70-,T95I,C136F,V143-,Y145-,S151-,W152-,L176F,N211-,L212I,+214EPE,I231T,G339D,R346K,N354K,S371L,R403K,K417T,F486V,S494P,G496S,T547K,M740I,R765-,N856K,D936G,L981F,P1079S,P1162L,E1258Q]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,F486P,F490S,Y505H,N764K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,F1103S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,T33K,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N658Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,K790T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,T1231I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,M740T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,K97N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,P39L,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1099D,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,V635F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V622F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[L5F,+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[E180V,T478R,P521T,D936H]-[Y144-,T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,P384S,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,Q949L,P1143L,A1226V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F175L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K147T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,L249S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547I,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1186I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,D88A,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 42 +[Q52H,F157L,H245Y,L452R,F456L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[V11I,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,A123S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E654V,P681R,D936Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,T33I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A892V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I693V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1130V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P862S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[T385I,F456L,T478R,A701V,D936Y]-[T478K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,K150R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S31F,S50L,H69-,V70-,P82S,V127F,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T632A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S31F,V47L,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 10 +[L18-,R21-,T22-,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,D287G,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+19I,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,T29N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D796H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,A668E,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,T73I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 20 +[Q52H,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V687I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 10 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V642F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,N556K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,L293F,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,D428H,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S366A,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,R78K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,N532S,E554K,A570V,P621S,P681R,S929T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,L293F,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,Q493L,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,P812S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S937T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,M177I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N149Y,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 49 +[T22I,F32S,Q52R,H69-,V70-,P139-,F140-,L141-,G142-,V143-,Y145-,G181V,K187I,N211-,L212I,V213G,A243-,L244-,Y248H,G339D,R346K,K444T,V445A,G446R,L452W,Y473F,T478Q,F486A,Q493L,P1143S]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,F486P,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683W,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,A1087S,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 13 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 16 +[+16MPLF,R21T,S50L,H69-,V70-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,N460K,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,D405N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1184N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1131A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,+374F,T376-,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,H49Y,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1259Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,+374F,T376-,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,P85L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1153V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 41 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E516Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,D405N,V445P,Q954H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,K790T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,K150N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N679T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V90I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[H49Y,Q52H,T307I,L455F,F456L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V126F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,G142Y,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258R,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,Q498R,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S1097L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A352S,K356T,R403K,V445H,G446N,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1162R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,S60P,H69-,V70-,V127F,S155R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K,G1251A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243T,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,T29N,G35R,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445L,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N658Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[V6A,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,N148S,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 46 +[Q14R,F79S,F186S,L455F,F456L,A475V,T478I,A522S,E554K]-[T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A783G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T678S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,+18L,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MLLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16IPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,S477D,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I870V,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211I,L212G,V213H,R214-,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V83I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185S,K187T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S813N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,P812S,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,Y28-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255Y,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+19I,R21-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1247S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1266E]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,A288V,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y145P,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q779K,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1201R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,I1130V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,+18V,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,K790E,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,P39L,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q779Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A783V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251T,S255F,A262V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q690E,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,N856S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A701T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69Y,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,L118I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I997V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V362F,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[Q14K,Q52H,L455F,F456L,M1233I] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,P561S,A570V,P621S,P681R,S939F,P1143L,C1248Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P809S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[Q14R,Q52H,A348S,L455F,F456L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[Q14K,Q52H,L455F,F456L,K1266R] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 33 +[Q14K,Q52H,V445H,N450D,L452W,L455S,N481K,V483-,E484K,P1143L]-[V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[Q14R,Q52H,G75V,L455F,F456L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V952I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,+374F,T376-,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q954Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H,N969K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,I670V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,P621S,Q677L,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1154R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,F338L,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,P621S,P681R,A829T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T523N,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,T827I,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[Q14R,+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,G1085R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,A475T,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1248F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 12 +[N17M,+17P,+18FNII,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V407I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,L552F,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,T1273S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,D178N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,Y421H,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,P621S,P681R,A701V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,E1111Q,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,I670M,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,W886L,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[Q14R,Q52H,I434V,L455F,F456L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 45 +[Q14K,Q52H,G184S,Y269H,L455F,F456L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,A163V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 46 +[Q14K,Q52H,T95I,L455F,F456L,S704L,I1232T] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,D428V,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,V62F,H69-,V70-,V127F,N148K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1158S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1158S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 20 +[S50L,H69-,V70-,V127F,F157S,R158G,F306L,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,F59S,W64R,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V642F,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1099V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P812S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 12 +[S50L,H69-,V70-,V127F,F157S,R158G,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P1143L]-[V83A,H146Q,G252V,R346T,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1250F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,L293F,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 13 +[S50L,H69-,V70-,V127F,F157S,R158G,L216F,H245N,I332V,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,S939F]-[V83A,H146Q,Q183E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V159I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V687L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,S151I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,P82T,V127F,M153V,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,V62I,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547I,E554K,A570V,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[L5F,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,V227I,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1219V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 15 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,I332V,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,R346T,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1192D,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,R78K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,N532S,E554K,A570V,P621S,P681R,S929T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A701V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,P82S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D936Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,S151G,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,I666V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 42 +[Q52H,F456L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 18 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,A348S,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[L5F,+19I,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 10 +[N17M,+17P,+18FI,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1085E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,G1124V,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,G476-,T478N,+478K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182Q,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[S13I,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,T1116N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,T1116N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Y170N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273M,I332L,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,R78M,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A871V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T573I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T716R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153V,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1188D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,+209V,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,H49Y,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 13 +[N17M,+17P,+18FNII,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,I105V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688T,S939F,P1143L,D1153H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A942T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,T76S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 46 +[Q14K,Q52H,M177I,L455F,F456L,S494P,T572I] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,T547I,E554K,A570V,P621S,P681R,A924S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 41 +[Q52H,F157S,L455F,F456L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,C1236F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16IPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,N856S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 15 +[S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S359G,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,V705F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,T29N,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1210T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1181N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,L517I,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,P337S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,E1207D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,R567K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,R567K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1195Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,R78M,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1084E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N960S,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,E96D,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T573I,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1073N,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,D88G,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16IPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,D420N,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,L249F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 40 +[H146K,P621S,K1045R]-[H146Q] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T618S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H66R,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[S12F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,V642A,P681-,+683Q,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,P479L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,D1118V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,T676N,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q836R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1132T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[F2L,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D843G,S939F,V1104L,P1143L,S1252P]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,E96G,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,N87D,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A846V,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,L1244I,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 42 +[Q14-,C15-,V16-,A27-,H69-,V70-,V213G,G339D,L452R,N460Y,F486V,K558N,A570T,T791P]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 14 +[R21T,S50L,H69-,V70-,V127F,E156D,F157-,R158-,V159-,Y160-,S161-,S162-,A163-,N164-,N165-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683Q,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H66Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,G1085R,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q52H,W152L,L455F,F456L,S704L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,T29I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S640F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,K854Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,S60A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,A123V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,I358V,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250I,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21-,+22S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,D88G,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,V42I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[+16MPLF,R21T,S50L,H69-,V70-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Q498R,N501Y,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 13 +[N17M,+17P,+18FNFI,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,D138H,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,N1023K,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,F92L,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,Y279H,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 43 +[Q52H,N450D,L455F,F456L,T478R,S704L]-[T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E654V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,F92L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21-,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A942S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T747I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T747I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S929N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,L945F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 15 +[V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 47 +[N148T,N185I,F186-,D253G,R408N,T478R,P521S,Q787K]-[G252V,R408S,T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,G1219V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1157N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[P25-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1124V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[L7V,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P807Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 50 +[K77R,N148T,N185I,F186-,D253G,+374F,T376-,P521S,S929T]-[G252V,S375F,T376A,T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,E132A,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,K147N,F157S,R158G,N211-,L212I,V213G,L216F,A222T,H245N,A264D,A292T,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,Q677L,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211I,+211G,V213-,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[V6A,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1118Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,E465D,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A899S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,D614G,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1146H,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,G35C,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,D111N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,A123S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,T33K,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 41 +[Q14K,Q52H,N211-,L212I,V213G,L455F,F456L,P1162S]-[V213E] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[V6I,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T883I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S640Y,N641-,P681R,T747I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T732I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1027S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,R78K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1070S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K417S,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K417S,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1257E]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V622-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 49 +[C15-,V16-,N17-,L18-,T19-,T20-,R21-,T22-,Q23-,H69-,V70-,T95I,L118F,Y145C,V213G,G339Y,E406Q,L452R,S494P,P1143S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,G35R,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,P39L,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V382L,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,P337L,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,T791I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,T33I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,R646H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,A27-,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,H69-,V70-,V127F,F157S,R158G,Q173H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1261P]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,K97N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T732A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S373P,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,S60F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,R102G,V127F,F157S,R158G,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1219C]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483R,E484-,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,T33I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,Q52E,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478E,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,E96D,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,I68T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,L1049I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,T547K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339Y,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q52H,L84I,L455F,F456L,G482R] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,A27-,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 25 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,+363TRISNCVATRISNCVATRISNCV,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T732I,S939F,G946E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 25 +[S12F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,+363TRISNCVATRISNCVATRISNCV,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T859A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 42 +[Q52H,N450D,L455F,F456L,G482R] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,D138Y,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21I,T22I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V642A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 13 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,A292E,L296P,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,F562S,P621S,P681R,P812L,T881P,I882V,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,F888L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,N30S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,D80G,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,I402V,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V83I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,K147-,N149-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1170P]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,Q675H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q675R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,V642F,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1172V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,D178N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[P25-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,D88G,V127F,D138H,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,F565L,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,D88G,V127F,D138H,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1079S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,P39T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V826L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,L293I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S929T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,R78K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1085R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69Y,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253Y,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N641S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A520S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,Y248H,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,S162I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1262K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T734I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,Y1007D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,F643-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,K150E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N679M,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A520S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,W152L,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,N969K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482R,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,E340Q,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,N658K,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376V,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1239T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1239T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,S161A,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,S60Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,Q954L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,R190M,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1244F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1122L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E654V,P681R,S939F,G1085E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q14K,Q52H,L455F,F456L,G946R] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,I197M,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1260Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,P209H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T470I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[L18F,+18I,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,G639S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I794T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I934M,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N1125S,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[S50L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218E,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S929G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1182Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A701S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q14K,Q52H,R237K,L455F,F456L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[Q14K,Q52H,G184A,L455F,F456L,T883I] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,K458N,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 46 +[Q14R,Q52H,L455F,F456L,A688V,F797L,D1153H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,R408G,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[Q14R,Q52H,L455F,F456L,F797L,D1153H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,L293F,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478I,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V687L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1266R]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683L,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,Y508H,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,V615I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,N334S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,L517P,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A520S,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,V503I,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,D138G,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,G35S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A852V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1073M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,+18L,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,G639D,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F140S,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481E,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 12 +[S50L,F58L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 43 +[Q52H,H146K,L455W,F456L,T478R]-[H146Q,T478K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 15 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 19 +[S50L,H69-,V70-,V127F,L216F,H245N,A264D,P330S,I332V,K356T,R403K,V445H,L455S,T478R,E554K,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,R346T,L368I,V445P,T478K,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 45 +[Q52H,H146K,L455W,F456L,T478R]-[G142D,Y144-,H146Q,T478K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 12 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688T,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,R1185H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,D178Y,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547I,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 43 +[Y200C,T478R,T572I]-[T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,R190M,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,Q52K,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,A292T,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 45 +[Q14K,Q52H,D215H,L455F,F456L,A475V] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q52H,T240I,L455F,F456L,S704L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S875A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260T,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q173R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,+18V,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,W64R,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,P479L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,I105L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16IPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21-,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K304N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S373P,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,I105L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T286I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 50 +[P25S,A67S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,Q675H,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940F,P1143L,A1174T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253N,W258R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N658T,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,M1237L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455P,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683Q,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1136I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,F486L,E554K,A570V,P621S,R634H,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,E96D,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,Q690H,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D839E,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,F306L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 43 +[Q52H,Q218R,L455F,F456L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,A845D,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[A67S,Y200C,S494P,T572I] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A771S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A352S,K356T,R403K,V445H,N450D,L452W,L455S,K458M,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1020V,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21-,+22N,P39H,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1263L,V1268F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,L249F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,Q613H,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,I624F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 41 +[Q52H,F140-,V445H,L455F,F456L,P621S]-[V445P] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[R21-,+22N,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218H,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A262V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,P57S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,T33I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21I,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,D936H,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,T76I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N282S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,G219V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I818V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,N148T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,L293F,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N960S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,A123T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 42 +[M153I,R403K,N440R,F456L]-[N440K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,K150R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 62 +[Q14-,C15-,V16-,W64G,C136F,V143D,Y145-,F175L,Y200C,K206N,N211-,L212I,L229F,A243-,L244-,G252S,G339D,R346K,K417Y,G446D,N448S,L452Q,K462T,T478E,E484K,Q493L,G496D,G504D,K558N,P681R,S704L,T827K,T859I]-[V83A,H146Q,Q183E,G252V,G339H,R346T,L368I,S373P,S375F,T376A,K417N,N440K,V445P,G446S,T478K,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 61 +[Q14-,C15-,V16-,W64G,C136F,V143D,Y145-,F175L,Y200C,K206N,N211-,L212I,L229F,A243-,L244-,G252S,G339D,R346K,K417Y,G446D,N448S,L452Q,K462T,T478E,E484K,Q493L,G496D,G504D,P681R,S704L,T827K,A1020S]-[V83A,H146Q,Q183E,G252V,G339H,R346T,L368I,S373P,S375F,T376A,K417N,N440K,V445P,G446S,T478K,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 62 +[Q14-,C15-,V16-,W64G,C136F,V143D,Y145-,F175L,Y200C,K206N,N211-,L212I,L229F,A243-,L244-,G252S,G339D,R346K,K417Y,G446D,N448S,L452Q,K462T,T478E,E484K,Q493L,G496D,G504D,K558N,P681R,S704L,T827K,A1020S]-[V83A,H146Q,Q183E,G252V,G339H,R346T,L368I,S373P,S375F,T376A,K417N,N440K,V445P,G446S,T478K,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,T33I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K528I,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MRV,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,D1168H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1068I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323K,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264G,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,M731I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,+149N,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A783V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,V382L,R403K,V445H,N450D,L452W,L455S,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D936Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150I,F157S,R158G,G181R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,M177T,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435T,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[N185D,L455F,F456L,A475V,E654A,S704L] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPV,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,E654Q,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[Q14K,Q52H,N185D,L455F,F456L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,R1185H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256P,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S813G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1076I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,N556K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,I670V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,G75S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E661D,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S750N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1128I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 12 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,H245N,A264D,K356T,R403K,V445H,N450D,L452W,L455S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,G252V,L368I,V445P,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q804K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,I1114T,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1234I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1078T,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221P,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,H519Y,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252D,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R847K,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T961M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1198V,M1229I,G1251R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,L118I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 45 +[Q14K,Q52H,L455F,F456L,P812L,M1233I] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,L110F,D111-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y145L,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I909V,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59-,+60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1083Y,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,E1202K,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,H49Y,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,P337S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A831V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y145D,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,N30H,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y144N,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,D389G,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,H625R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,S1030L,F1075L,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,R246K,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A944S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1070S,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T604I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N211-,L212I,V213G,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S371F,N440K,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,F220L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,L513F,E554K,A570V,P621S,P681R,Q836L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S813I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1150V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[Q14K,Q52H,L455F,F456L,T572I] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260T,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 42 +[Q52H,F157L,L455F,F456L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,A623-,I624-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1219V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,G75V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 41 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,Q836K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 45 +[Q52H,F140L,F157L,L452R,F456L,T478R,D796H]-[T478K,D796Y] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,F306L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 14 +[N17M,+17P,+18FNFI,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 46 +[E180V,S373T,T478R,A647S,S735L,A958D]-[S373P,T478K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 44 +[Q52H,T274I,L455F,F456L,S704L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 45 +[Q14K,Q52H,D138N,L455F,F456L,E471Q] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1045R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,S112A,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 15 +[N17M,+17P,+18FNFI,R21-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,F186L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,E465G,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 39 +[K147E,M153T,N164K,V213G,H245N,S255A,G257D,G339D,R403K,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D745G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 50 +[H69-,V70-,D80E,K147N,M153T,F157L,A163V,V213G,G339D,E340K,N440R,L452R,F486V,H519Q,I624M,L752F,Q836P,D843G,S939F,N960S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,N440K,V445P,G446S,N460K,F486P,F490S,N764K] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,F1075L,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,H519Y,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S982L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S46T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,N99D,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,E465G,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445Y,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P809S,S939F,P1143L,I1183V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 52 +[H69-,V70-,H146N,K147E,K150R,W152R,F157L,G181R,I210V,V213G,D215G,G257S,G261A,F377L,R403K,K444T,L452R,T500-,+501Y,Q613H,S982L,V987F,R1091H,T1117K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,N501Y,Y505H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,S60A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261-,+264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,F1103S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,G476-,T478N,+478K,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,D138N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1127N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483R,E484-,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,D138G,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,L54F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,S1021F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,G842S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,G75D,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A522S,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,F92L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K278E,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A942V,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1084Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,T73I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K187S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,E96Q,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D796H,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H,D796Y] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,N703S,S939F,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1216V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,Y1155H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,D111N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D745G,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 13 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T676N,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,S60C,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1252P]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 15 +[+16MPLF,R21T,S50L,H69-,V70-,R102G,V127F,F157S,R158G,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P812S,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483R,E484-,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,D80H,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263P,A264D,I332V,K356T,R403K,V445H,N450D,L452W,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,N487S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,I68F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,Y145L,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A831V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1146G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q675R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,T33I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,D427N,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,G75S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,P209H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 44 +[Q52H,S71F,K356T,R408G,L455F,F456L,N703I]-[R408S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A783S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683Q,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P812T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,K529N,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1085R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1265F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N641I,V642-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,F541C,N542-,F543-,N544-,G545-,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[F2L,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q836K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218H,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R357G,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1183V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,M177I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,Q836R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,T547I,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[R21T,N30I,S31-,F32-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S375-,T376-,F377-,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1079S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 15 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[Q52H,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S373P,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1227T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,A672V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445Y,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A520S,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1225T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1199N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,W152R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211I,+211G,V213-,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A701V,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452R,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N501Y,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452R,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N658H,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 14 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,V445H,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,Y505H,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,G482-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 11 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,Q913H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,D80Y,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[Q14H,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,L861S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A846V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,S155I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[L7F,L8F,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPVF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 46 +[H146K,F456L,T478R,V656I,A701V,T732I,Q836R]-[H146Q,T478K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,T478E,N481K,G482D,V483-,E484K,E554K,A570V,P621S,A623-,I624-,P681R,A879T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272S,R273S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1122L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L,I1172T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 18 +[N17M,+17P,+18FNFI,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,T478E,N481K,G482D,V483-,E484K,E554K,A570V,P621S,A623-,I624-,P681R,A879T,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,K458N,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1163N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 20 +[N17M,+17P,+18FNFI,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,T478E,N481K,G482-,E554K,A570V,P621S,A623-,I624-,P681R,A879T,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,G476-,T478N,+478K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,T478K,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 12 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V407I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 62 +[Q14-,C15-,V16-,W64G,C136F,V143D,Y145-,F175L,Y200C,K206N,N211-,L212I,L229F,A243-,L244-,G252S,G339D,R346K,K417Y,G446D,N448S,L452Q,K462T,T478E,E484K,Q493L,G496D,G504A,K558N,P681R,S704L,T827K,A1020S]-[V83A,H146Q,Q183E,G252V,G339H,R346T,L368I,S373P,S375F,T376A,K417N,N440K,V445P,G446S,T478K,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A871V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 61 +[Q14-,C15-,V16-,W64G,C136F,V143D,Y145-,F175L,Y200C,K206N,N211-,L212I,L229F,A243-,L244-,G252S,G339D,R346K,K417Y,G446D,N448S,L452Q,K462T,T478E,E484K,Q493L,G496D,G504D,K558N,P681R,S704L,T827K]-[V83A,H146Q,Q183E,G252V,G339H,R346T,L368I,S373P,S375F,T376A,K417N,N440K,V445P,G446S,T478K,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,P561H,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q173H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 61 +[Q14-,C15-,V16-,W64G,C136F,V143D,Y145-,F175L,Y200C,K206N,N211-,L212I,L229F,A243-,L244-,G252S,G339D,R346K,K417Y,G446D,N448S,L452Q,K462T,E484K,Q493L,G496D,G504D,K558N,P681R,S704L,T827K,A1020S]-[V83A,H146Q,Q183E,G252V,G339H,R346T,L368I,S373P,S375F,T376A,K417N,N440K,V445P,G446S,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1163Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,P217S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A783K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 49 +[F59S,P139S,V143D,Y144K,Y145-,H146-,A243-,L244-,E406Q,N481K,F490Y,P621S,A623V,K854N,V1177L]-[Y144-,H146Q,F490S] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258C,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1165G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[+16MPLF,R21T,F32S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482-,E484K,E554K,A570V,P621S,P681R,T732I,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,R246K,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,Q677H,P681R,A688V,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211I,+211G,V213-,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,Q1071L,P1143L,E1182D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,E1182D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,S477D,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D745G,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,I651V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1076S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[P9L,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,D1084Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,S112P,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211I,L212G,V213H,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y144N,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,D936Y,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T961M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,H69-,V70-,I101L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 10 +[R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L,L1203F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,Q173H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 50 +[K77R,N148T,N185I,F186-,D253G,+374F,T376-,P521S,Q1201K]-[G252V,S375F,T376A,T478K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,V642F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,P561H,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,G842S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,P809S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,N969K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D745A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481R,V483-,E484K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R765C,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,E619-,V620-,P621-,V622-,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,S373P,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,N764K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,K77N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,T109S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N960S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,D111N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,R765G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,T1231I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255-,S256-,G257-,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 15 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,V642A,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,A520S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,L84I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,K854N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,R634H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P793S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,P862S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,I670V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16IPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,I68T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,V143F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,R102G,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,V510I,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,D427Y,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,P217S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[L5F,+16IPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[+16MPLF,R21-,+22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,G184V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,T638I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S45F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A879S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,E156Q,F157S,R158G,K182-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 5 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 8 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,Y279F,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 42 +[Q52H,N148T,R403K,F456L] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1101Q,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 6 +[R21T,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 9 +[R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[R21T,P39H,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[R21T,S50L,H69-,V70-,T95I,V127F,H146K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 7 +[V3I,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,K1191N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K304N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,Y248H,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y145R,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1200I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 9 +[S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 17 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G339D,V445D,N450D,L452W,L455S,R466T,D467-,I468-,S469-,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 7 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 45 +[E180V,F338L,F456L,T478R]-[K417N,T478K] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S735A,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 6 +[+16MPLF,R21T,S50L,H69-,V70-,S98F,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 0/1 0.00000/0.00012 +0.01% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,Y269H,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 16773 1 0.0% 1/0 0.00012/0.00000 -0.01% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,R567K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H]
last modified: Mon Jan 8 13:32 2024
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Questions or comments? Contact us at seq-info@lanl.gov.
