COVID-19 Viral Genome Analysis Pipeline
Enabled by data from
Most common forms based on Pango lineage designations
Last update: May 15, 2024
Geographically local data, different time windows, and different proteins can be evaluated here
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SPIKE sequences: Short list of All days
Compute mutations relative to XBB.1.5 baseline sequence
As new lineages emerge, there are often many sequences with many ambiguous base calls. Our pipeline filters out such sequences, and as a consequence we undercount the number of sequences in GISAID that have been specified as members of related Pango lineages. Our strategy, however, enables us to use strictly high quality sequences to identify and track the common forms in emerging lineages.
COMMON FORMS OF SPIKE WITH A GIVEN PANGO LINEAGE DESIGNATION
For each lineage, we show the most common forms of SPIKE, as well as their counts within (and percentages of) the lineage. [Note that if a lineage contains several divergent forms, the consensus form might not be found among these common forms.] Also shown is the Hamming distance (HD) between each form and the most common form in that lineage. Deletions relative to the baseline reference strain are indicated with a dash (e.g. the two amino acid deletion at positions 156-157 is indicated with 'E156-,F157-'), and insertions are denoted by a plus sign (e.g. an extra T at position 143 is written '+143T'). [Note: Mutation strings are relative to baseline XBB.1.5].
We show the 5 most common forms. This output is based on sequences sampled from 2013-07-24 to 2024-05-08.
Baseline XBB.1.5: [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
Pango Lineage Form Form Lineage Count Count Pct HD [Form as mutation string] B.1.1.7 930795 591643 63.6% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.7 930795 23596 2.5% 1 +[H69-,V70-,A570D,T716I,S982A,D1118H,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.7 930795 20061 2.2% 1 +[L5F,H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.7 930795 10418 1.1% 1 +[H69-,V70-,W152R,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.7 930795 7732 0.8% 1 +[H69-,V70-,S98F,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.2 824557 628063 76.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2 824557 18561 2.3% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2 824557 16922 2.1% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2 824557 7519 0.9% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2 824557 5267 0.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.4 583593 350180 60.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4 583593 12538 2.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4 583593 10546 1.8% 1 +[T19R,T95I,D138H,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4 583593 8477 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,L1141F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4 583593 5364 0.9% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1 465066 356286 76.6% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1 465066 14865 3.2% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1 465066 6273 1.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1 465066 3905 0.8% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1 465066 3495 0.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.1 227526 166583 73.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.1 227526 3537 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.1 227526 3087 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.1 227526 2519 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.1 227526 1452 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.12.1 214295 165707 77.3% 0 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.12.1 214295 11821 5.5% 1 +[N164K,V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.1 214295 2598 1.2% 1 +[V213G,G339D,L452Q,Q493R,S704L,A879V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.1 214295 2406 1.1% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.12.1 214295 1963 0.9% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2 211105 146905 69.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2 211105 3200 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2 211105 2996 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2 211105 1936 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2 211105 1917 0.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.103 200924 108978 54.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.103 200924 24549 12.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103 200924 3113 1.5% 1 +[T19R,D80Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103 200924 1672 0.8% 1 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103 200924 1199 0.6% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43 189023 93306 49.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43 189023 27566 14.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43 189023 1974 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43 189023 1828 1.0% 1 +[V6F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43 189023 1526 0.8% 1 +[T19R,A67S,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1 174432 131756 75.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1 174432 7281 4.2% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1 174432 1669 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1 174432 1462 0.8% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1 174432 1250 0.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.5.1 162894 117034 71.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1 162894 4485 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1 162894 2593 1.6% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1 162894 1752 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1 162894 1750 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.617.2 158946 37583 23.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.617.2 158946 29601 18.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.2 158946 8110 5.1% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.2 158946 6670 4.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.2 158946 4511 2.8% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.44 158854 87927 55.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.44 158854 20296 12.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.44 158854 1210 0.8% 1 +[T19R,E156G,F157-,R158-,R214H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.44 158854 1027 0.6% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.44 158854 934 0.6% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122 129487 48060 37.1% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122 129487 14104 10.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122 129487 3566 2.8% 1 +[T19R,E156G,F157-,R158-,T240I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122 129487 2580 2.0% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122 129487 2523 1.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A879S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.9 128513 96155 74.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9 128513 6505 5.1% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9 128513 3452 2.7% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.9 128513 1111 0.9% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9 128513 557 0.4% 1 +[L179P,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1 114979 68621 59.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1 114979 12951 11.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1 114979 843 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1 114979 750 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1 114979 629 0.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] AY.3 111665 51639 46.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.3 111665 13725 12.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3 111665 4836 4.3% 1 +[T19R,V70I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3 111665 1873 1.7% 2 +[T19R,V70I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3 111665 1649 1.5% 2 +[T19R,V70I,E156G,F157-,R158-,M177I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.2 107341 54567 50.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.2 107341 6083 5.7% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.2 107341 2890 2.7% 2 +[L18F,E780Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.2 107341 2809 2.6% 1 +[Q677P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.2 107341 2513 2.3% 1 +[Q173K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5 100964 65551 64.9% 0 (consensus) XBB.1.5 100964 2687 2.7% 1 +[H146K]-[H146Q] XBB.1.5 100964 1541 1.5% 1 -[K417N] XBB.1.5 100964 918 0.9% 1 +[L5F] XBB.1.5 100964 464 0.5% 1 -[R408S] AY.25.1 95836 62881 65.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.25.1 95836 6555 6.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1 95836 967 1.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A846S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1 95836 795 0.8% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1 95836 627 0.7% 1 +[T19R,V70F,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25 93246 34621 37.1% 0 +[T19R,S112L,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.25 93246 19129 20.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25 93246 8331 8.9% 1 +[T19R,S112L,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25 93246 4715 5.1% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25 93246 1365 1.5% 1 +[T19R,S112L,E156G,F157-,R158-,L452R,A522V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3 87253 65654 75.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3 87253 3554 4.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3 87253 1412 1.6% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3 87253 837 1.0% 2 +[V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3 87253 553 0.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.1.15 84442 65750 77.9% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.15 84442 2936 3.5% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15 84442 919 1.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,K854N,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15 84442 708 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.15 84442 618 0.7% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,L452R,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] B.1 82541 53024 64.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1 82541 1410 1.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1 82541 1376 1.7% 1 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1 82541 845 1.0% 2 +[M153T,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1 82541 706 0.9% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.17.2 80921 58994 72.9% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.17.2 80921 5606 6.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,F643L,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.2 80921 1970 2.4% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.2 80921 518 0.6% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.2 80921 399 0.5% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.29 80022 59183 74.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.29 80022 1475 1.8% 1 +[T19R,T95I,E156G,F157-,R158-,R237S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29 80022 1456 1.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29 80022 1088 1.4% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29 80022 821 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,R408I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.5 72713 56937 78.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.5 72713 728 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5 72713 624 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.5 72713 438 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.5 72713 269 0.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.4.2 72045 50818 70.5% 0 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2 72045 1344 1.9% 1 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2 72045 995 1.4% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,H1083Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2 72045 692 1.0% 1 +[L5F,T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2 72045 667 0.9% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177 60755 23587 38.8% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177 60755 13219 21.8% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177 60755 3486 5.7% 3 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177 60755 1250 2.1% 2 +[A222V,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177 60755 969 1.6% 3 +[A222V,D1163Y,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1 58726 34721 59.1% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1 58726 1583 2.7% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,A688V,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1 58726 1491 2.5% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1 58726 1484 2.5% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1 58726 576 1.0% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,D427N,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.2 58390 52041 89.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.2 58390 1005 1.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,M153T,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.2 58390 518 0.9% 1 +[A67V,H69-,V70-,T76I,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.2 58390 335 0.6% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.2 58390 270 0.5% 1 +[A67V,H69-,V70-,D88E,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.100 58233 30460 52.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.100 58233 7734 13.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.100 58233 654 1.1% 1 +[T19R,T95I,E156G,F157-,R158-,T385I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.100 58233 626 1.1% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.100 58233 570 1.0% 1 +[T19R,P82T,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.5 46402 36321 78.3% 0 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.5 46402 808 1.7% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.5 46402 632 1.4% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,K1073T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5 46402 461 1.0% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5 46402 384 0.8% 1 +[L5F,H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1 45519 36338 79.8% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1 45519 936 2.1% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1 45519 847 1.9% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.1 45519 207 0.5% 1 +[V3G,H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1 45519 181 0.4% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.18 43854 18730 42.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.18 43854 18225 41.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.18 43854 935 2.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.18 43854 791 1.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.18 43854 390 0.9% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.5 42597 28039 65.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5 42597 3655 8.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5 42597 703 1.7% 1 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5 42597 427 1.0% 1 +[T19R,E156G,F157-,R158-,T376I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5 42597 345 0.8% 2 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,V772I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.10 41767 33466 80.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.10 41767 1068 2.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.10 41767 815 2.0% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10 41767 559 1.3% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10 41767 455 1.1% 1 +[V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6 40672 31065 76.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.6 40672 673 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.6 40672 435 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.6 40672 305 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6 40672 273 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1 40473 24184 59.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1 40473 800 2.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1 40473 366 0.9% 3 +[W152L,E484K,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1 40473 361 0.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1 40473 269 0.7% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1 40405 24681 61.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1 40405 4109 10.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1 40405 595 1.5% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1 40405 314 0.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1 40405 266 0.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] BE.1.1 37149 28167 75.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.1 37149 900 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.1 37149 319 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BE.1.1 37149 292 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1 37149 268 0.7% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7 36665 25264 68.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7 36665 642 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7 36665 476 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7 36665 351 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7 36665 255 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BQ.1 36496 19430 53.2% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1 36496 6342 17.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1 36496 596 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1 36496 361 1.0% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1 36496 350 1.0% 1 +[H69-,V70-,V213G,P251H,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.526 35135 15227 43.3% 0 +[L5F,T95I,D253G,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.526 35135 6269 17.8% 4 +[L5F,T95I,D253G,Q957R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.526 35135 2134 6.1% 2 +[L5F,T95I,D253G,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.526 35135 1056 3.0% 1 +[L5F,T95I,D253G,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.526 35135 805 2.3% 5 +[L5F,L18F,T95I,D253G,Q957R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39 35056 16489 47.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39 35056 4159 11.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39 35056 1119 3.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39 35056 808 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39 35056 793 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.6 31280 24236 77.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.6 31280 434 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.6 31280 359 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.6 31280 184 0.6% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6 31280 156 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.98 30986 16080 51.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.98 30986 1695 5.5% 2 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N,D1127G]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98 30986 1490 4.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98 30986 951 3.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98 30986 943 3.0% 1 +[T19R,E96V,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.17 30530 22636 74.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.17 30530 1024 3.4% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17 30530 724 2.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,S1147L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17 30530 315 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.17 30530 288 0.9% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.9.2 29969 16126 53.8% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.9.2 29969 3845 12.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2 29969 947 3.2% 1 +[T19R,A67V,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2 29969 348 1.2% 1 +[T19R,E156G,F157-,R158-,D215H,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2 29969 291 1.0% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HV.1 29887 18167 60.8% 0 +[Q52H,F157L,L452R,F456L] (consensus) HV.1 29887 873 2.9% 1 +[Q52H,F157L,K444T,L452R,F456L] HV.1 29887 822 2.8% 1 +[Q52H,H146K,F157L,L452R,F456L]-[H146Q] HV.1 29887 333 1.1% 1 +[Q52H,F157L,L452R,F456L,L1265F] HV.1 29887 323 1.1% 1 +[Q52H,F157L,L452R,F456L,A1078S] AY.126 28031 10938 39.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,I850L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.126 28031 2891 10.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,I850L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.126 28031 492 1.8% 3 +[T19R,E156G,F157-,R158-,L452R,P681R,S689I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.126 28031 474 1.7% 1 +[T19R,T95I,E156G,F157-,R158-,E281Q,L452R,P681R,I850L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.126 28031 460 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.18 27546 22754 82.6% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.18 27546 577 2.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.18 27546 293 1.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.1.1.18 27546 208 0.8% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.18 27546 190 0.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] AY.26 27333 7197 26.3% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.26 27333 5541 20.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,N1074S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.26 27333 2579 9.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.26 27333 2196 8.0% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,N1074S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.26 27333 619 2.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,T547I,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160 26980 19982 74.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160 26980 386 1.4% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160 26980 197 0.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160 26980 192 0.7% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160 26980 177 0.7% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4 26083 10714 41.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4 26083 7734 29.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4 26083 577 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4 26083 402 1.5% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,S640F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4 26083 382 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,D936N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.47 25965 14747 56.8% 0 +[T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.47 25965 5219 20.1% 1 +[T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.47 25965 364 1.4% 2 +[T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.47 25965 212 0.8% 1 +[L5F,T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.47 25965 111 0.4% 2 +[L5F,T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.1 25878 19465 75.2% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.1 25878 818 3.2% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.1 25878 715 2.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.1 25878 252 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,D1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.1 25878 240 0.9% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] EG.5.1.1 25668 13935 54.3% 0 +[Q52H,F456L] (consensus) EG.5.1.1 25668 1758 6.8% 1 +[Q52H,L455F,F456L] EG.5.1.1 25668 547 2.1% 1 +[Q52H,H146K,F456L]-[H146Q] EG.5.1.1 25668 361 1.4% 2 +[Q52H,L455F,F456L,G482R] EG.5.1.1 25668 351 1.4% 1 +[Q52H,F456L,S494P] B.1.429 24720 16111 65.2% 0 +[S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.429 24720 1981 8.0% 1 +[S13I,P26S,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.429 24720 264 1.1% 1 +[L5F,S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.429 24720 227 0.9% 1 +[S13I,W152C,A222V,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.429 24720 134 0.5% 1 +[S13I,W152C,L452R,L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119 24249 8742 36.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.119 24249 4557 18.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P809S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119 24249 1921 7.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119 24249 1232 5.1% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P809S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119 24249 421 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P809S,G946R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.2 24236 13882 57.3% 0 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2.2 24236 2165 8.9% 1 +[S13T,T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.2 24236 1338 5.5% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,T299I,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.2 24236 1007 4.2% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1133I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.2 24236 930 3.8% 1 +[L18F,T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120 21308 11433 53.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.120 21308 3186 15.0% 1 +[T19R,T51I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120 21308 532 2.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120 21308 302 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,V407I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120 21308 285 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,R1091H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1 20519 9865 48.1% 0 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.98.1 20519 4506 22.0% 1 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1 20519 421 2.1% 1 +[T19R,D80Y,E156G,F157-,R158-,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1 20519 300 1.5% 2 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1 20519 233 1.1% 1 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,A942S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Unassigned 20191 5132 25.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] Unassigned 20191 1936 9.6% 5 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] Unassigned 20191 1731 8.6% 30 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Unassigned 20191 1145 5.7% 33 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Unassigned 20191 864 4.3% 35 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.5 19987 13162 65.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5 19987 519 2.6% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5 19987 389 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5 19987 333 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,N460S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5 19987 270 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.121 19939 7610 38.2% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.121 19939 3275 16.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121 19939 683 3.4% 1 +[T19R,T95I,E156G,F157-,R158-,E180Q,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121 19939 221 1.1% 2 +[T19R,T95I,E156G,F157-,R158-,E180Q,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121 19939 191 1.0% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.1 19939 13517 67.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1 19939 855 4.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1 19939 835 4.2% 1 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1 19939 311 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1 19939 141 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.20 19852 5739 28.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.20 19852 2842 14.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.20 19852 2015 10.2% 1 +[T19R,T95I,K97E,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.20 19852 973 4.9% 2 +[T19R,T95I,K97E,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.20 19852 714 3.6% 2 +[T19R,T95I,K97E,E156G,F157-,R158-,L452R,P681R,D950N,V1104L,V1177I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.2 19679 8175 41.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.99.2 19679 4108 20.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.2 19679 1443 7.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.2 19679 192 1.0% 1 +[T19R,E156G,F157-,R158-,D178H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.2 19679 142 0.7% 1 +[T19R,E156G,F157-,R158-,L452R,S640F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.519 19240 13186 68.5% 0 +[T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.519 19240 434 2.3% 1 +[L5F,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.519 19240 235 1.2% 1 +[T732A,E1258D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.519 19240 190 1.0% 2 +[A292S,T604A,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.519 19240 186 1.0% 1 +[P174S,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.214 19079 10924 57.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.214 19079 2856 15.0% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.214 19079 696 3.6% 1 +[I720V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.214 19079 319 1.7% 1 +[S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.214 19079 302 1.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HK.3 19074 10204 53.5% 0 +[Q52H,L455F,F456L] (consensus) HK.3 19074 423 2.2% 1 +[Q52H,H146K,L455F,F456L]-[H146Q] HK.3 19074 273 1.4% 1 +[Q52H,P174S,L455F,F456L] HK.3 19074 263 1.4% 1 +[Q52H,L455F,F456L,A475V] HK.3 19074 237 1.2% 1 +[Q14R,Q52H,L455F,F456L] AY.6 18789 11207 59.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.6 18789 1569 8.4% 2 +[T19R,T22I,A67V,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.6 18789 444 2.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.6 18789 350 1.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,I1115V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.6 18789 247 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,V483F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.27 18652 12139 65.1% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.27 18652 3041 16.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.27 18652 361 1.9% 1 +[T19R,E156G,F157-,R158-,L179F,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.27 18652 248 1.3% 1 +[L18F,T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.27 18652 207 1.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,A684S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.16 18642 9989 53.6% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16 18642 516 2.8% 3 +[E180V,T478R,Q613H,Q675K,V1230A]-[T478K] XBB.1.16 18642 358 1.9% 1 +[E180V,T478R]-[K417N,T478K] XBB.1.16 18642 270 1.4% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16 18642 178 1.0% 1 +[E180V,T478R,Q613H]-[T478K] AY.127 18606 7054 37.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.127 18606 1356 7.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T859N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127 18606 1053 5.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127 18606 743 4.0% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127 18606 628 3.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,D574N,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.10 18183 13173 72.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.10 18183 809 4.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.10 18183 179 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.10 18183 176 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.10 18183 155 0.9% 2 +[W64C,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.125 17372 8345 48.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.125 17372 4196 24.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125 17372 292 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125 17372 291 1.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,A879S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125 17372 208 1.2% 1 +[L18F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.20 17101 11541 67.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.20 17101 467 2.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.20 17101 323 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.20 17101 241 1.4% 1 +[H69-,V70-,K147T,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.20 17101 222 1.3% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] P.1.14 17005 10691 62.9% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.14 17005 905 5.3% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.14 17005 341 2.0% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,I844V,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.14 17005 311 1.8% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.14 17005 277 1.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,L938F,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.20 16408 12921 78.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.20 16408 473 2.9% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.20 16408 148 0.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.20 16408 123 0.7% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.1.20 16408 106 0.6% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.46.6 16133 7232 44.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.6 16133 3433 21.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.6 16133 334 2.1% 1 +[T19R,H69Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.6 16133 302 1.9% 1 +[T19R,E156G,F157-,R158-,T323K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.6 16133 238 1.5% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.15.1 16097 13378 83.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.15.1 16097 300 1.9% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.1 16097 120 0.7% 1 +[A67V,H69-,V70-,T95I,D138N,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.1 16097 101 0.6% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.1 16097 77 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] AY.42 16003 3769 23.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.42 16003 3024 18.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T719I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.42 16003 2003 12.5% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T719I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.42 16003 1751 10.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.42 16003 268 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T719I,T732I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.4 15814 9209 58.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.4 15814 2123 13.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4 15814 172 1.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4 15814 115 0.7% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4 15814 115 0.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] AY.75 15249 8496 55.7% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.75 15249 2461 16.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75 15249 167 1.1% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75 15249 141 0.9% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,T1231A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75 15249 129 0.8% 1 +[T19R,E156G,F157-,R158-,A222V,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.1 15087 11802 78.2% 0 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2.1 15087 358 2.4% 1 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,A899S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.1 15087 262 1.7% 1 +[T19R,V36F,G75R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.1 15087 206 1.4% 1 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,N1187S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.1 15087 197 1.3% 1 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,P809L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.5 15080 14530 96.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.5 15080 57 0.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.5 15080 46 0.3% 1 +[V213G,R214H,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.5 15080 34 0.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.5 15080 26 0.2% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23 14737 12750 86.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.23 14737 176 1.2% 1 +[V213G,G339D,Q493R,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23 14737 114 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.23 14737 111 0.8% 2 +[V213G,G339D,K356R,Q493R,A845G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23 14737 99 0.7% 1 +[K187R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.118 14512 8210 56.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.118 14512 2311 15.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.118 14512 476 3.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.118 14512 160 1.1% 1 +[V11I,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.118 14512 127 0.9% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.5.1 14362 8205 57.1% 0 +[Q52H,F456L] (consensus) EG.5.1 14362 360 2.5% 1 +[Q52H,H146K,F456L]-[H146Q] EG.5.1 14362 234 1.6% 1 +[T19L,Q52H,F456L]-[T19I] EG.5.1 14362 212 1.5% 1 +[Q52H,L455F,F456L] EG.5.1 14362 186 1.3% 3 +[Q52H,K182Q,L455F,F456L,T478R]-[T478K] AY.23 13278 7497 56.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.23 13278 1407 10.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23 13278 352 2.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A845S,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23 13278 171 1.3% 3 +[T19R,H69-,V70-,E156G,F157-,R158-,D215N,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23 13278 142 1.1% 1 +[T19R,E156G,F157-,R158-,D215Y,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.6 13142 8491 64.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.6 13142 808 6.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.6 13142 161 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.6 13142 126 1.0% 1 +[H69-,V70-,Q183P,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.6 13142 124 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.9 13129 9684 73.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.9 13129 407 3.1% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.9 13129 261 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.9 13129 121 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.9 13129 92 0.7% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.30 13014 10225 78.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.30 13014 275 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.30 13014 224 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.30 13014 113 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.30 13014 98 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.39.1 12884 8314 64.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.1 12884 1655 12.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1 12884 197 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1 12884 163 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,V227I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1 12884 133 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,S813N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243 12866 4295 33.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.243 12866 2776 21.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243 12866 613 4.8% 2 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243 12866 374 2.9% 3 +[A520S,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243 12866 373 2.9% 1 +[Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.2.1 12857 11148 86.7% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.1 12857 198 1.5% 1 +[V213G,T240P,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.1 12857 171 1.3% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.1 12857 102 0.8% 1 +[V213G,G339D,Q493R,E654Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.1 12857 96 0.7% 1 +[V213G,A262S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.22 12763 9598 75.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.22 12763 518 4.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.22 12763 313 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.22 12763 106 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.22 12763 96 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,L1244F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CH.1.1 12707 8544 67.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1 12707 140 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q1113K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1 12707 121 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1 12707 112 0.9% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1 12707 90 0.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T323A,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FL.1.5.1 12533 7893 63.0% 0 +[F456L,T478R,A701V]-[T478K] (consensus) FL.1.5.1 12533 270 2.2% 1 +[F456L,T478R,E554K,A701V]-[T478K] FL.1.5.1 12533 230 1.8% 1 +[H146K,F456L,T478R,A701V]-[H146Q,T478K] FL.1.5.1 12533 120 1.0% 1 +[F456L,T478R,A701V]-[K417N,T478K] FL.1.5.1 12533 111 0.9% 2 +[F456L,T478R,F490P,E554K,A701V]-[T478K,F490S] AY.33 12420 2665 21.5% 0 +[T19R,T29A,E156G,F157-,R158-,T250I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33 12420 2004 16.1% 2 +[T19R,T29A,E156G,F157-,R158-,T250I,T299I,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33 12420 1301 10.5% 1 +[T19R,T29A,E156G,F157-,R158-,T250I,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.33 12420 817 6.6% 3 +[T19R,T29A,E156G,F157-,R158-,T250I,T299I,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33 12420 666 5.4% 1 +[T19R,T29A,E156G,F157-,R158-,T250I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258 12096 5491 45.4% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258 12096 1680 13.9% 2 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258 12096 280 2.3% 3 +[N439K,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258 12096 270 2.2% 2 +[H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258 12096 217 1.8% 1 +[H69-,V70-,N439K,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.21 12092 9310 77.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.21 12092 670 5.5% 1 +[A222V,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.21 12092 472 3.9% 1 +[A222V,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.21 12092 136 1.1% 1 +[W64C,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.21 12092 129 1.1% 1 +[G181R,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.23 11974 8697 72.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.23 11974 318 2.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.23 11974 156 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.23 11974 118 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.23 11974 96 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.1 11689 10293 88.1% 0 +[V213G,G339D,Q493R,Q677E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.1 11689 100 0.9% 1 +[V213G,G339D,Q493R,Q677E,R847K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.1 11689 74 0.6% 1 +[V213G,G339D,Q493R,Q677E,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.1 11689 67 0.6% 1 +[V213G,G339D,Q493R,Q677E,R1014K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.1 11689 57 0.5% 1 +[L5F,V213G,G339D,Q493R,Q677E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.221 11573 8356 72.2% 0 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.221 11573 332 2.9% 1 +[S98F,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221 11573 111 1.0% 1 +[S98F,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221 11573 99 0.9% 1 +[S98F,K182R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221 11573 85 0.7% 2 +[S98F,A1078S,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.1 11390 5773 50.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.3.1 11390 2328 20.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.1 11390 178 1.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A846V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.1 11390 125 1.1% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,A701V,A846V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.1 11390 116 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.14 10765 8943 83.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.14 10765 135 1.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.14 10765 134 1.2% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.14 10765 88 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.14 10765 71 0.7% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.5.1.1 10722 8276 77.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.1 10722 163 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.1 10722 117 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.1 10722 106 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.1 10722 86 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] JN.1.1 10694 6957 65.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.1 10694 824 7.7% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1 10694 58 0.5% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1 10694 54 0.5% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1 10694 39 0.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] AY.117 10638 5886 55.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.117 10638 1412 13.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.117 10638 275 2.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.117 10638 158 1.5% 1 +[T19R,T95I,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.117 10638 113 1.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1199N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.637 10524 5625 53.4% 0 +[D80G,F157S,L452R,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.637 10524 859 8.2% 1 +[D80G,F157S,L452R,T791I,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.637 10524 356 3.4% 1 +[D80G,S155R,F157S,L452R,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.637 10524 290 2.8% 1 +[D80G,F157S,L452R,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.637 10524 169 1.6% 2 +[H69Y,D80G,F157S,L452R,T791I,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.5 10262 8214 80.0% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.5 10262 224 2.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.5 10262 118 1.1% 1 +[T19R,E156G,F157-,R158-,L452R,E583D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.5 10262 115 1.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.5 10262 109 1.1% 1 +[T19R,E156G,F157-,R158-,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351 10201 2900 28.4% 0 +[D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.351 10201 2292 22.5% 1 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351 10201 434 4.3% 2 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351 10201 402 3.9% 1 +[D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351 10201 196 1.9% 2 +[L18F,D80A,D215G,L242-,A243-,L244-,P384L,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1 10050 5856 58.3% 0 +[F486S]-[F486P] (consensus) XBB.1 10050 324 3.2% 1 +[F486S]-[K417N,F486P] XBB.1 10050 166 1.7% 1 +[H146K,F486S]-[H146Q,F486P] XBB.1 10050 147 1.5% 21 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,S704L,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBB.1 10050 108 1.1% 1 +[F486S]-[G142D,F486P] AY.69 9965 3872 38.9% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.69 9965 2635 26.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.69 9965 818 8.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.69 9965 196 2.0% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.69 9965 127 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.15 9914 8244 83.2% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.15 9914 269 2.7% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.15 9914 151 1.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.15 9914 97 1.0% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.15 9914 53 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,V826L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XBB.1.16.6 9899 6770 68.4% 0 +[E180V,F456L,T478R]-[T478K] (consensus) XBB.1.16.6 9899 338 3.4% 1 +[H146K,E180V,F456L,T478R]-[H146Q,T478K] XBB.1.16.6 9899 199 2.0% 1 +[E180V,L455F,F456L,T478R]-[T478K] XBB.1.16.6 9899 122 1.2% 1 +[E180V,K304N,F456L,T478R]-[T478K] XBB.1.16.6 9899 97 1.0% 1 +[E180V,F456L,T478R]-[K417N,T478K] BA.2.18 9519 7895 82.9% 0 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.18 9519 199 2.1% 1 +[V213G,S254F,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.18 9519 185 1.9% 1 +[L176F,V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.18 9519 180 1.9% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.18 9519 76 0.8% 1 +[L5F,V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] B.1.1.284 9469 3716 39.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.284 9469 3548 37.5% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.284 9469 453 4.8% 3 +[M153T,G184S,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.284 9469 184 1.9% 2 +[M153T,P793S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.284 9469 135 1.4% 2 +[M153T,S255Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.427 9413 4552 48.4% 0 +[S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.427 9413 1723 18.3% 1 +[S13I,W152C,W258L,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.427 9413 493 5.2% 1 +[S13I,W152C,L452R,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.427 9413 159 1.7% 1 +[P9L,S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.427 9413 99 1.1% 1 +[L5F,S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.21 9315 7664 82.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.21 9315 103 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1116N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.21 9315 99 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.21 9315 91 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.21 9315 69 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.4.6 9279 6266 67.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.6 9279 718 7.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.6 9279 508 5.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.6 9279 287 3.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.6 9279 122 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,A222S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.3 9217 6153 66.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3 9217 116 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.3 9217 83 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N481K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3 9217 69 0.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,P631S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3 9217 54 0.6% 1 +[K147E,W152R,F157L,I210V,V213G,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.2.29 9184 8152 88.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.29 9184 121 1.3% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.29 9184 96 1.0% 1 +[V213G,G339D,Q493R,N703H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.29 9184 34 0.4% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.29 9184 31 0.3% 1 +[V213G,G339D,Q493R,A845S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.36 9137 4983 54.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.36 9137 982 10.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36 9137 745 8.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36 9137 157 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36 9137 122 1.3% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.1 9014 6711 74.5% 0 +[W152L,E484K,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) R.1 9014 302 3.4% 1 +[W152L,E484K,G769V,K795N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.1 9014 276 3.1% 1 +[W152L,E484K,G769V,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.1 9014 118 1.3% 1 +[W152L,E484K,N751D,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.1 9014 117 1.3% 1 +[W152L,S255F,E484K,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.26 8983 5290 58.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.26 8983 928 10.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.26 8983 345 3.8% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.26 8983 132 1.5% 1 +[T22I,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.26 8983 100 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.10 8850 5402 61.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.10 8850 691 7.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.10 8850 141 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.10 8850 115 1.3% 3 +[L5F,I68-,H69-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.10 8850 114 1.3% 1 +[H69-,V70-,Y145H,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.9 8550 5932 69.4% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.9 8550 412 4.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9 8550 190 2.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9 8550 145 1.7% 1 +[T19R,E156G,F157-,R158-,L189F,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9 8550 91 1.1% 1 +[T19R,D138Y,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.24 8477 7424 87.6% 0 +[V213G,G339N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.24 8477 103 1.2% 1 +[L5F,V213G,G339N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.24 8477 93 1.1% 1 +[V213G,G339N,Q493R,I844V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.24 8477 49 0.6% 2 +[F157S,V213G,G339N,Q493R,V1264M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.24 8477 46 0.5% 1 +[V213G,G339N,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.113 8323 4950 59.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.113 8323 907 10.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.113 8323 81 1.0% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.113 8323 80 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] AY.113 8323 51 0.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.5 8227 5158 62.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.5 8227 304 3.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.5 8227 114 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D796H,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.5 8227 113 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,G769V,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.5 8227 106 1.3% 1 +[L18F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.65 7999 6079 76.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.65 7999 213 2.7% 1 +[V213G,G339N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.65 7999 151 1.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.65 7999 103 1.3% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.65 7999 72 0.9% 1 +[V213G,G339D,Q493R,E1195G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] D.2 7932 6784 85.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) D.2 7932 205 2.6% 1 +[V1068F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.2 7932 135 1.7% 1 +[T632N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.2 7932 79 1.0% 1 +[A930V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.2 7932 73 0.9% 1 +[S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.14 7924 5180 65.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.14 7924 1084 13.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.14 7924 108 1.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.14 7924 81 1.0% 2 +[T19R,E156G,F157-,R158-,A348S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.14 7924 49 0.6% 1 +[T19R,E156G,F157-,R158-,L452R,T547I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.21 7880 5549 70.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.21 7880 328 4.2% 1 +[H69-,V70-,H146Y,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.21 7880 85 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1137I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.21 7880 78 1.0% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.21 7880 76 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.119.2 7842 4405 56.2% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.119.2 7842 895 11.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119.2 7842 749 9.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119.2 7842 184 2.3% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119.2 7842 107 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,G181V,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.9.1 7739 4355 56.3% 0 (consensus) XBB.1.9.1 7739 156 2.0% 1 +[H146K]-[H146Q] XBB.1.9.1 7739 98 1.3% 1 +[T478R]-[T478K] XBB.1.9.1 7739 96 1.2% 1 -[K417N] XBB.1.9.1 7739 89 1.2% 1 +[L5F] BA.2.36 7656 5805 75.8% 0 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.36 7656 278 3.6% 1 +[I68T,V213G,G339D,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.36 7656 235 3.1% 1 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.36 7656 93 1.2% 2 +[I68T,V213G,Y248H,G339D,Q493R,T791I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.36 7656 57 0.7% 1 +[I68T,T73N,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.1 7619 6004 78.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.1 7619 126 1.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.1 7619 105 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BF.1 7619 97 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1009I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.1 7619 73 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.18 7557 4979 65.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.18 7557 450 6.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.18 7557 169 2.2% 1 +[H69-,V70-,V213G,Y248H,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.18 7557 75 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.18 7557 67 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] AY.129 7495 3783 50.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.129 7495 1906 25.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.129 7495 168 2.2% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.129 7495 148 2.0% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,D950N,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.129 7495 38 0.5% 1 +[P9S,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.3 7473 5699 76.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.3 7473 228 3.1% 1 +[H69-,V70-,V213G,I231T,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.3 7473 146 2.0% 1 +[H69-,V70-,V213G,S254F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.3 7473 78 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.3 7473 49 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] JD.1.1 7399 4644 62.8% 0 +[L455F,F456L,A475V] (consensus) JD.1.1 7399 141 1.9% 1 +[L455F,F456L,A475V,D1153H] JD.1.1 7399 97 1.3% 1 +[H146K,L455F,F456L,A475V]-[H146Q] JD.1.1 7399 74 1.0% 1 +[L455F,F456L,A475V,Q677R] JD.1.1 7399 59 0.8% 1 +[L455F,F456L,A475V,E554Q] BQ.1.1.4 7373 4546 61.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.4 7373 647 8.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.4 7373 143 1.9% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q675H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.4 7373 127 1.7% 1 +[H69-,V70-,W152R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.4 7373 70 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A701S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.2 7275 4719 64.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.2 7275 251 3.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2 7275 189 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2 7275 122 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2 7275 113 1.6% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EG.5.1.3 7248 5167 71.3% 0 +[Q52H,F456L] (consensus) EG.5.1.3 7248 170 2.3% 1 +[Q52H,H146K,F456L]-[H146Q] EG.5.1.3 7248 68 0.9% 2 +[Q52H,L455F,F456L,S704L] EG.5.1.3 7248 56 0.8% 1 +[Q52H,F456L]-[Y144-] EG.5.1.3 7248 54 0.7% 1 +[Q52H,F456L]-[K417N] C.37 7188 3660 50.9% 0 +[G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.37 7188 306 4.3% 1 +[G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,Q675H,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.37 7188 214 3.0% 1 +[G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,I714V,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.37 7188 102 1.4% 13 +[T63-,W64-,F65-,H66-,A67-,H69-,V70-,S71-,G72-,T73-,N74-,G75-,T76-,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.37 7188 96 1.3% 8 +[G75V,T76I,L452Q,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.54 7157 4227 59.1% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.54 7157 1216 17.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.54 7157 72 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.54 7157 65 0.9% 1 +[T19R,T22I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.54 7157 51 0.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,N777S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JG.3 7064 2907 41.2% 0 +[Q52H,L455F,F456L,S704L] (consensus) JG.3 7064 869 12.3% 1 +[Q52H,N450D,L455F,F456L,S704L] JG.3 7064 434 6.1% 1 +[Q52H,T307I,L455F,F456L,S704L] JG.3 7064 229 3.2% 4 +[Q52H,+214YRR,N450D,L455F,F456L,S704L] JG.3 7064 77 1.1% 1 +[Q52H,H146K,L455F,F456L,S704L]-[H146Q] B.1.234 7044 4223 60.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.234 7044 487 6.9% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.234 7044 354 5.0% 3 +[G142S,E180V,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.234 7044 180 2.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.234 7044 138 2.0% 4 +[G142S,E180V,Q677H,S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.13 6995 6015 86.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.13 6995 163 2.3% 1 +[V213G,G339D,Q493R,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.13 6995 76 1.1% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.13 6995 75 1.1% 1 +[M153I,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.13 6995 35 0.5% 1 +[V213G,G339D,Q493R,D1146H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2 6969 6258 89.8% 0 +[V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.2 6969 55 0.8% 1 +[V213G,G339D,K356R,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2 6969 42 0.6% 29 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.2.2 6969 30 0.4% 1 +[L176F,V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2 6969 29 0.4% 1 +[L5F,V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.34 6918 3438 49.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.34 6918 1164 16.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34 6918 151 2.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34 6918 103 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,A1016V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34 6918 99 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.621 6899 3177 46.1% 0 +[T95I,+143T,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.621 6899 492 7.1% 1 +[T95I,+143T,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621 6899 362 5.2% 1 +[T95I,+143T,Y144S,Y145N,R346K,E484K,D950N,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621 6899 214 3.1% 1 +[T95I,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621 6899 138 2.0% 1 +[T95I,+143T,Y144S,Y145N,R346K,E484K,T572I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BF.28 6885 3428 49.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.28 6885 1573 22.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A701S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.28 6885 162 2.4% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,A701S,D820E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.28 6885 148 2.1% 2 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.28 6885 76 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.11 6870 4830 70.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.11 6870 114 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q607L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11 6870 105 1.5% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11 6870 83 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11 6870 81 1.2% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.3 6854 5128 74.8% 0 +[H69-,V70-,V213G,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.3 6854 170 2.5% 1 +[H69-,V70-,V213G,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.3 6854 114 1.7% 1 +[H69-,V70-,V213G,D215V,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.3 6854 88 1.3% 1 +[L5F,H69-,V70-,V213G,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.3 6854 74 1.1% 1 +[H69-,V70-,V213G,V289I,G339D,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.1 6830 5235 76.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.4.1 6830 151 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.1 6830 92 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.1 6830 63 0.9% 2 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.1 6830 53 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D745G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBF 6818 5100 74.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF 6818 87 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G446N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S] XBF 6818 65 1.0% 1 +[W64L,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF 6818 47 0.7% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF 6818 44 0.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L1224V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] B.1.258.17 6642 4986 75.1% 0 +[H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.17 6642 126 1.9% 1 +[P26L,H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.17 6642 65 1.0% 1 +[H69-,V70-,L189F,S256P,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.17 6642 56 0.8% 1 +[H69-,V70-,L189F,N439K,V772I,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.17 6642 52 0.8% 1 +[L5F,H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46 6594 3549 53.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46 6594 588 8.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46 6594 161 2.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,K835R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46 6594 156 2.4% 1 +[T19R,E132A,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46 6594 87 1.3% 2 +[T19R,T20I,E156G,F157-,R158-,L452R,S640F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.8 6525 6043 92.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.8 6525 78 1.2% 1 +[V213G,G339D,Q493R,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.8 6525 34 0.5% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.8 6525 20 0.3% 1 +[V83F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.8 6525 18 0.3% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BC.1 6395 5817 91.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BC.1 6395 74 1.2% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,M153T,N211-,L212I,+214EPE,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BC.1 6395 67 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BC.1 6395 31 0.5% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BC.1 6395 24 0.4% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.2.56 6294 4469 71.0% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.56 6294 271 4.3% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.56 6294 182 2.9% 1 +[V213G,R214L,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.56 6294 104 1.7% 1 +[V213G,G339D,L452M,Q493R,Q787H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.56 6294 102 1.6% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.438.1 6239 3692 59.2% 0 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.438.1 6239 632 10.1% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.1 6239 563 9.0% 1 +[A653V,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.1 6239 206 3.3% 1 +[I233V,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.1 6239 153 2.5% 1 +[Q613H,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.5 6239 4160 66.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.5 6239 194 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.5 6239 105 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,M1229T,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.5 6239 76 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.5 6239 68 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.111 6212 4039 65.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.111 6212 314 5.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.111 6212 205 3.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.111 6212 120 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,N354K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.111 6212 108 1.7% 3 +[T19R,T95I,E156G,F157-,R158-,N211-,L212I,L452R,P681R,D950N,V1094I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.9 6118 3882 63.5% 0 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.9 6118 216 3.5% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.9 6118 157 2.6% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.9 6118 115 1.9% 1 +[H69-,V70-,V213G,S256L,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.9 6118 72 1.2% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,N460H,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.2 6113 4785 78.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.2 6113 125 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.2 6113 83 1.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.2 6113 73 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1250Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.2 6113 64 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.2 6107 4231 69.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2 6107 138 2.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2 6107 84 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.2 6107 54 0.9% 1 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2 6107 50 0.8% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.5.2.12 6073 4173 68.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.12 6073 897 14.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.12 6073 71 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,E1202A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.12 6073 44 0.7% 1 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.12 6073 41 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.12 5947 4171 70.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.12 5947 1097 18.4% 1 +[A222V,K1073T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.12 5947 184 3.1% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.12 5947 106 1.8% 1 +[A222V,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.12 5947 28 0.5% 1 +[G181V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.37 5935 5068 85.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.37 5935 117 2.0% 1 +[V213G,V227L,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.37 5935 78 1.3% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.37 5935 74 1.2% 1 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.37 5935 64 1.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.3 5898 4289 72.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.3 5898 171 2.9% 1 +[H69-,V70-,G75A,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.3 5898 95 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.3 5898 70 1.2% 1 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.3 5898 67 1.1% 1 +[L5I,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.27 5892 4640 78.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.27 5892 124 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.27 5892 121 2.1% 2 +[H69-,V70-,H146-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.27 5892 56 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.27 5892 50 0.8% 1 +[H69-,V70-,F157L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.16.1 5849 3922 67.1% 0 +[E180V,T478R,T547I]-[T478K] (consensus) XBB.1.16.1 5849 114 1.9% 1 +[H146K,E180V,T478R,T547I]-[H146Q,T478K] XBB.1.16.1 5849 66 1.1% 1 +[E180V,T478R,T547I,E554K]-[T478K] XBB.1.16.1 5849 65 1.1% 1 +[E180V,T478R,P521S,T547I]-[T478K] XBB.1.16.1 5849 52 0.9% 1 +[E180V,T478R,T547I]-[K417N,T478K] B.1.36 5811 2622 45.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36 5811 349 6.0% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36 5811 173 3.0% 1 +[I210-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36 5811 105 1.8% 1 +[Q23R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36 5811 98 1.7% 1 +[M1050I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.2 5805 3925 67.6% 0 +[E484K,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.2 5805 284 4.9% 1 +[E484K,F565L,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.2 5805 79 1.4% 1 +[L5F,E484K,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.2 5805 46 0.8% 1 +[E484K,T859I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.2 5805 32 0.6% 1 +[E484K,P809S,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.4 5775 4069 70.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.4 5775 601 10.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.4 5775 137 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.4 5775 58 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.4 5775 42 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] Q.3 5751 3673 63.9% 0 +[H69-,V70-,D178H,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.3 5751 1208 21.0% 1 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.3 5751 149 2.6% 2 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.3 5751 65 1.1% 2 +[H69-,V70-,M177I,D178H,A222V,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.3 5751 30 0.5% 1 +[H69-,V70-,M177I,D178H,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.1.16 5664 3430 60.6% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.16 5664 1262 22.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,V1264M]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16 5664 77 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,D627G,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16 5664 76 1.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16 5664 41 0.7% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,H625R,N856K,L981F,V1264M]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BF.7.14 5635 4261 75.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14 5635 65 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691F,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14 5635 50 0.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14 5635 33 0.6% 1 +[H69-,V70-,V213G,G339D,S366A,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14 5635 28 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,E1202Q,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.1.13 5590 4748 84.9% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.13 5590 172 3.1% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.13 5590 60 1.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.13 5590 44 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212-,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.13 5590 28 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,K417T,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] Q.1 5391 4079 75.7% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.1 5391 186 3.5% 1 +[H69-,V70-,A570D,T632S,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.1 5391 100 1.9% 1 +[H69-,V70-,A570D,T716I,T732I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.1 5391 81 1.5% 2 +[H69-,V70-,V367A,E484K,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.1 5391 52 1.0% 1 +[L18F,H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XBB.1.16.11 5388 3537 65.6% 0 +[E180V,T478R,P521T]-[T478K] (consensus) XBB.1.16.11 5388 163 3.0% 1 +[G72E,E180V,T478R,P521T]-[T478K] XBB.1.16.11 5388 88 1.6% 1 +[E180V,S256L,T478R,P521T]-[T478K] XBB.1.16.11 5388 65 1.2% 1 +[H146K,E180V,T478R,P521T]-[H146Q,T478K] XBB.1.16.11 5388 58 1.1% 1 +[R78K,E180V,T478R,P521T]-[T478K] AY.124 5361 1981 37.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.124 5361 1161 21.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124 5361 139 2.6% 2 +[L8V,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124 5361 83 1.5% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124 5361 83 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,A688V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.74 5361 3979 74.2% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.74 5361 224 4.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.74 5361 171 3.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.74 5361 74 1.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.74 5361 56 1.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,A688V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.10 5358 2791 52.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.10 5358 1186 22.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10 5358 94 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10 5358 92 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10 5358 37 0.7% 1 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.2.10.1 5261 3985 75.7% 0 +[V213G,G339D,Q493R,G798D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.10.1 5261 174 3.3% 2 +[T19L,V159I,V213G,G339D,Q493R,G798D]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.1 5261 99 1.9% 1 +[V213G,G339D,Q493R,G798D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.10.1 5261 95 1.8% 1 +[V213G,G339D,Q493R,Q677H,G798D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.1 5261 58 1.1% 1 +[L5F,V213G,G339D,Q493R,G798D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.7.1 5241 3084 58.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.7.1 5241 662 12.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A688V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.1 5241 635 12.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.1 5241 52 1.0% 2 +[T19R,E156G,F157-,R158-,A263V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.1 5241 50 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.6 5231 4687 89.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.6 5231 73 1.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,R1091H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.6 5231 36 0.7% 1 +[T19R,D80Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.6 5231 28 0.5% 1 +[T19R,E156G,F157-,R158-,T274I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.6 5231 26 0.5% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.525 5195 3111 59.9% 0 +[Q52R,A67V,H69-,V70-,E484K,Q677H,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.525 5195 188 3.6% 1 +[Q52R,A67V,H69-,V70-,E484K,Q677H,D839Y,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.525 5195 92 1.8% 1 +[Q52R,A67V,H69-,V70-,K150N,E484K,Q677H,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.525 5195 73 1.4% 1 +[A67V,H69-,V70-,E484K,Q677H,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.525 5195 68 1.3% 1 +[Q52R,A67V,H69-,V70-,G181A,E484K,Q677H,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.12 5153 4147 80.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.12 5153 98 1.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.12 5153 42 0.8% 1 +[H69-,V70-,V213G,S254F,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.12 5153 40 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N679K] BQ.1.12 5153 21 0.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I584V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B 5134 4139 80.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B 5134 136 2.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B 5134 38 0.7% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B 5134 22 0.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B 5134 21 0.4% 1 +[S50L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.3 5113 2973 58.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.3 5113 592 11.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.3 5113 220 4.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.3 5113 91 1.8% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.3 5113 86 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.1.14 5054 3942 78.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.14 5054 124 2.5% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.14 5054 94 1.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.14 5054 63 1.2% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.14 5054 55 1.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.5.3.1 5011 3006 60.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3.1 5011 189 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.1 5011 158 3.2% 3 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.3.1 5011 153 3.1% 2 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V,A829T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.1 5011 101 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A829T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.24 5004 4066 81.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.24 5004 82 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.24 5004 78 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.24 5004 42 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.24 5004 40 0.8% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] P.1.17 4999 3660 73.2% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.17 4999 160 3.2% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,D936Y,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17 4999 95 1.9% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17 4999 66 1.3% 1 +[L18F,T20N,P26S,G75V,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17 4999 61 1.2% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F,E1258D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.369 4989 1973 39.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.369 4989 621 12.4% 1 +[E780Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.369 4989 311 6.2% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.369 4989 266 5.3% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.369 4989 156 3.1% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240 4973 2622 52.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.240 4973 620 12.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240 4973 275 5.5% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240 4973 158 3.2% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240 4973 101 2.0% 1 +[A575S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.60 4967 3173 63.9% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.60 4967 180 3.6% 1 +[L5F,L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.60 4967 173 3.5% 1 +[L18F,A222V,R1091H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.60 4967 124 2.5% 2 +[L18F,A222V,K558N,V687I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.60 4967 81 1.6% 1 +[L18F,A222V,A879V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.6 4874 3355 68.8% 0 +[D253G,F486S]-[G252V,F486P] (consensus) XBB.2.6 4874 281 5.8% 1 +[D253G,F486S]-[G252V,R408S,F486P] XBB.2.6 4874 81 1.7% 1 +[H146K,D253G,F486S]-[H146Q,G252V,F486P] XBB.2.6 4874 70 1.4% 1 +[D253G,F486S]-[Q183E,G252V,F486P] XBB.2.6 4874 51 1.0% 1 +[N148T,D253G,F486S]-[G252V,F486P] JN.1.4.5 4816 2941 61.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.4.5 4816 679 14.1% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.5 4816 133 2.8% 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.5 4816 66 1.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.5 4816 46 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] B.1.177.86 4775 2794 58.5% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.86 4775 604 12.6% 1 +[L18F,A222V,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.86 4775 215 4.5% 2 +[L18F,A222V,T547I,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.86 4775 146 3.1% 1 +[L18F,A222V,Q779K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.86 4775 119 2.5% 1 +[L18F,A222V,A1070S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FU.1 4750 3526 74.2% 0 +[E180V,T478R,T547I]-[T478K] (consensus) FU.1 4750 128 2.7% 1 +[E180V,T478R,T547I,N703Y]-[T478K] FU.1 4750 57 1.2% 1 +[H146K,E180V,T478R,T547I]-[H146Q,T478K] FU.1 4750 39 0.8% 1 +[E180V,T478R,T547I]-[Y144-,T478K] FU.1 4750 31 0.7% 2 +[N74S,E180V,T478R,T547I,K1266R]-[T478K] CH.1.1.1 4723 3442 72.9% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.1 4723 55 1.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.1 4723 51 1.1% 1 +[K147E,W152R,F157L,N185D,F186L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.1 4723 33 0.7% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q675K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.1 4723 32 0.7% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BF.14 4669 3427 73.4% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.14 4669 95 2.0% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,D1118Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.14 4669 59 1.3% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,I742V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.14 4669 53 1.1% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.14 4669 47 1.0% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.39.1.1 4666 3538 75.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.1.1 4666 377 8.1% 1 +[T19R,T95I,E156G,F157-,R158-,G219D,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.1 4666 172 3.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,R765H,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.1 4666 113 2.4% 1 +[T19R,R21T,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.1 4666 85 1.8% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,N481K,P681R,R765H,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BR.2.1 4631 3733 80.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BR.2.1 4631 34 0.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I,N556K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2.1 4631 33 0.7% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2.1 4631 31 0.7% 1 +[K147E,W152R,F157L,I210V,L212S,V213G,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2.1 4631 26 0.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I,Q1208H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.12 4612 3796 82.3% 0 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.12 4612 73 1.6% 1 +[G75V,V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12 4612 68 1.5% 1 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.12 4612 58 1.3% 1 +[L5F,V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12 4612 34 0.7% 1 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BQ.1.14 4592 3332 72.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.14 4592 140 3.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.14 4592 79 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E1258D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.14 4592 49 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.14 4592 42 0.9% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] AY.34.1 4487 1849 41.2% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.34.1 4487 594 13.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,V1133I,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1 4487 488 10.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1 4487 218 4.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,V1264A,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1 4487 86 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,P174S,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.1 4468 3614 80.9% 0 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.29.1 4468 151 3.4% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.1 4468 94 2.1% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,T553I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.1 4468 87 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.1 4468 47 1.1% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L176F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.1 4458 2497 56.0% 0 +[Q613H] (consensus) EG.1 4458 314 7.0% 1 +[Q613H,G1124V] EG.1 4458 70 1.6% 1 +[H146K,Q613H]-[H146Q] EG.1 4458 62 1.4% 1 +[L452R,Q613H] EG.1 4458 44 1.0% 2 +[T29I,Q613H,A706V] B.1.1.222 4447 1878 42.2% 0 +[T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.222 4447 168 3.8% 1 +[G257S,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.222 4447 160 3.6% 1 +[T732A,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.222 4447 149 3.4% 2 +[T732A,A1078S,V1228I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.222 4447 140 3.1% 2 +[T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BF.8 4413 3430 77.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.8 4413 100 2.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.8 4413 58 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.8 4413 54 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.8 4413 35 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.2 4403 3398 77.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DY.2 4403 41 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1163V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.2 4403 35 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.2 4403 33 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.2 4403 20 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] GK.1.1 4370 2628 60.1% 0 +[L455F,F456L,T573I,S704L] (consensus) GK.1.1 4370 77 1.8% 1 +[H146K,L455F,F456L,T573I,S704L]-[H146Q] GK.1.1 4370 69 1.6% 1 +[L5F,L455F,F456L,T573I,S704L] GK.1.1 4370 55 1.3% 1 +[A262P,L455F,F456L,T573I,S704L] GK.1.1 4370 40 0.9% 1 +[L455F,F456L,T573I,S704L,G946V] XBB.1.9.2 4364 2115 48.5% 0 (consensus) XBB.1.9.2 4364 196 4.5% 2 +[Q52H,F456L] XBB.1.9.2 4364 103 2.4% 1 +[H146K]-[H146Q] XBB.1.9.2 4364 87 2.0% 1 +[I794T] XBB.1.9.2 4364 71 1.6% 2 +[V70A,C1247S] BF.7.4 4335 3348 77.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.4 4335 70 1.6% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4 4335 65 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T827I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4 4335 48 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.4 4335 30 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1263L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.81 4331 3076 71.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.81 4331 112 2.6% 1 +[A222V,T240I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.81 4331 110 2.5% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.81 4331 78 1.8% 1 +[A222V,D839Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.81 4331 52 1.2% 1 +[A222V,V227L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.3 4330 1863 43.0% 0 +[D253G,P521S]-[G252V] (consensus) XBB.2.3 4330 157 3.6% 1 +[G184V,D253G,P521S]-[G252V] XBB.2.3 4330 123 2.8% 1 +[I210-,D253G,P521S]-[G252V] XBB.2.3 4330 100 2.3% 1 +[D253G,S256T,P521S]-[G252V] XBB.2.3 4330 60 1.4% 1 +[D253G,T323I,P521S]-[G252V] BE.1.1.2 4265 3528 82.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.1.2 4265 93 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.1.2 4265 50 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1.2 4265 36 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BE.1.1.2 4265 35 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] FL.4 4264 2774 65.1% 0 (consensus) FL.4 4264 85 2.0% 1 +[H146K]-[H146Q] FL.4 4264 61 1.4% 1 +[R1014K] FL.4 4264 54 1.3% 1 -[K417N] FL.4 4264 35 0.8% 2 -[R408S,S477N] BF.7.5 4264 2615 61.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.5 4264 701 16.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.5 4264 51 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A845S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.5 4264 43 1.0% 2 +[V6I,H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.5 4264 38 0.9% 5 +[H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.8 4237 3134 74.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.8 4237 82 1.9% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.8 4237 68 1.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.8 4237 57 1.3% 1 +[H69-,V70-,V213G,D215Y,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.8 4237 53 1.3% 2 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,S940F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.5 4215 2103 49.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.5 4215 596 14.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.5 4215 151 3.6% 1 +[H69-,V70-,S98F,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.5 4215 129 3.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.5 4215 73 1.7% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.1.37 4213 2701 64.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.37 4213 326 7.7% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.37 4213 252 6.0% 4 +[L5F,A222V,D574Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.37 4213 216 5.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.37 4213 58 1.4% 1 +[P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.7 4198 3271 77.9% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.7 4198 216 5.1% 1 +[L18F,A222V,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.7 4198 151 3.6% 1 +[L18F,N185S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.7 4198 103 2.5% 1 +[L18F,A222V,S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.7 4198 60 1.4% 1 +[L18F,A67S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.3 4172 1670 40.0% 0 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2.3 4172 1012 24.3% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,L1049I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.3 4172 256 6.1% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.3 4172 161 3.9% 2 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,L1049I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.3 4172 42 1.0% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,P812L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.11 4094 2581 63.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.11 4094 324 7.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.11 4094 288 7.0% 1 +[H69-,V70-,W152L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.11 4094 117 2.9% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.11 4094 47 1.1% 1 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EG.5.1.4 4075 2599 63.8% 0 +[Q52H,F456L] (consensus) EG.5.1.4 4075 339 8.3% 1 +[Q52H,L455F,F456L] EG.5.1.4 4075 137 3.4% 1 +[Q52H,H146K,F456L]-[H146Q] EG.5.1.4 4075 44 1.1% 1 +[Q52H,F456L,V483I] EG.5.1.4 4075 41 1.0% 1 +[Q52H,F456L,E654K] BQ.1.1.5 4057 2577 63.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.5 4057 391 9.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.5 4057 58 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.5 4057 34 0.8% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.5 4057 32 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BF.7.15 4050 3321 82.0% 0 +[H69-,V70-,V213G,G257D,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.15 4050 99 2.4% 1 +[L8F,H69-,V70-,V213G,G257D,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.15 4050 59 1.5% 1 +[H69-,V70-,V213G,G257D,G339D,L452R,F486V,L752F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.15 4050 50 1.2% 1 +[H69-,V70-,V213G,G257D,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.15 4050 43 1.1% 1 +[L5F,H69-,V70-,V213G,G257D,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.28 4026 2175 54.0% 0 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.28 4026 160 4.0% 2 +[M153T,S689I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.28 4026 69 1.7% 2 +[A222V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.28 4026 63 1.6% 3 +[M153T,N658T,S689I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.28 4026 46 1.1% 6 +[G142V,N164K,Q173K,L452R,S704L,I720V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.23 4005 3031 75.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.23 4005 49 1.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.23 4005 35 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A1078S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.23 4005 34 0.8% 1 +[H69-,V70-,V213G,Q271K,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.23 4005 30 0.7% 1 +[H69-,V70-,S151T,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] AY.46.4 3982 2312 58.1% 0 +[T19R,E156G,F157-,R158-,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.4 3982 597 15.0% 1 +[T19R,E156G,F157-,R158-,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.4 3982 300 7.5% 1 +[T19R,E156G,F157-,R158-,A222S,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.4 3982 116 2.9% 2 +[T19R,E156G,F157-,R158-,A222S,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.4 3982 26 0.7% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.13 3944 2788 70.7% 0 (consensus) XBB.1.5.13 3944 55 1.4% 1 -[K417N] XBB.1.5.13 3944 50 1.3% 1 +[H146K]-[H146Q] XBB.1.5.13 3944 34 0.9% 1 +[P1162L] XBB.1.5.13 3944 23 0.6% 1 +[K150N] B.1.177.4 3919 3388 86.5% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.4 3919 76 1.9% 1 +[A222V,D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.4 3919 38 1.0% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.4 3919 18 0.5% 1 +[A222V,P1263T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.4 3919 14 0.4% 1 +[R21G,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.2 3850 3337 86.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AD.2 3850 93 2.4% 1 +[S71P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.2 3850 44 1.1% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.2 3850 21 0.5% 1 +[A626V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.2 3850 21 0.5% 1 +[L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.7 3834 2318 60.5% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] (consensus) P.1.7 3834 132 3.4% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7 3834 70 1.8% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E780A,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7 3834 62 1.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,Q613H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7 3834 60 1.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E654Q,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] BA.1.21 3807 3198 84.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.21 3807 117 3.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.21 3807 39 1.0% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214GAR,D215N,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.21 3807 30 0.8% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.21 3807 29 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.4.2 3783 3034 80.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.2 3783 103 2.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.2 3783 40 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.2 3783 39 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1164I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.2 3783 24 0.6% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.28 3758 2486 66.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.28 3758 114 3.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.28 3758 78 2.1% 1 +[H69-,V70-,V213G,G339D,S359N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.28 3758 55 1.5% 1 +[H69-,V70-,G184S,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.28 3758 47 1.3% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.34 3755 2522 67.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.34 3755 126 3.4% 1 +[H69-,V70-,V213G,D215E,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.34 3755 118 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.34 3755 53 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.34 3755 52 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.25 3748 2626 70.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.25 3748 155 4.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.25 3748 132 3.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.25 3748 93 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.25 3748 51 1.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.8 3733 2920 78.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.8 3733 143 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L,Q1201H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.8 3733 76 2.0% 1 +[H69-,V70-,W152R,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.8 3733 34 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.8 3733 34 0.9% 1 +[R21T,H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13 3724 2233 60.0% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.13 3724 899 24.1% 1 +[V213G,G339D,L452M,Q493R,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13 3724 70 1.9% 2 +[V213G,S255F,G339D,L452M,Q493R,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13 3724 43 1.2% 1 +[L5F,V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13 3724 35 0.9% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] DY.4 3717 2933 78.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DY.4 3717 75 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] DY.4 3717 30 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.4 3717 29 0.8% 1 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.4 3717 19 0.5% 1 +[H69-,V70-,V213G,T307I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BD.1 3685 3179 86.3% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BD.1 3685 47 1.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BD.1 3685 42 1.1% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BD.1 3685 39 1.1% 1 +[A67V,H69-,V70-,T95I,I105L,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BD.1 3685 32 0.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.122.5 3683 1779 48.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.5 3683 1034 28.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.5 3683 124 3.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.5 3683 117 3.2% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.5 3683 85 2.3% 2 +[T19R,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.22 3677 2795 76.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.22 3677 68 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.22 3677 60 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.22 3677 51 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.22 3677 45 1.2% 1 +[H69-,V70-,V213G,T250A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.4.8 3665 3026 82.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.8 3665 94 2.6% 1 +[T19R,T95I,E156G,F157-,R158-,G181R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.8 3665 34 0.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,A647S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.8 3665 33 0.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,T961M]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.8 3665 31 0.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.26 3616 2419 66.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.26 3616 128 3.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.26 3616 122 3.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.26 3616 55 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.26 3616 43 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.112 3609 1363 37.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.112 3609 582 16.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112 3609 135 3.7% 1 +[T19R,T95I,E156G,F157-,R158-,S254F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112 3609 60 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,S254F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112 3609 51 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,E1207D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GJ.1.2 3608 2265 62.8% 0 +[K182N,D253G,P521S]-[G252V] (consensus) GJ.1.2 3608 114 3.2% 1 +[H146K,K182N,D253G,P521S]-[H146Q,G252V] GJ.1.2 3608 63 1.7% 1 +[K182N,D253G,T478R,P521S]-[G252V,T478K] GJ.1.2 3608 46 1.3% 1 +[K150I,K182N,D253G,P521S]-[G252V] GJ.1.2 3608 38 1.1% 1 +[K182N,D253G,P521S]-[G252V,K417N] AY.43.8 3587 1990 55.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.8 3587 415 11.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.8 3587 166 4.6% 1 +[L18F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.8 3587 132 3.7% 1 +[T19R,E156G,F157-,R158-,R214L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.8 3587 43 1.2% 1 +[T19R,E156G,F157-,R158-,T323I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.1 3551 3118 87.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.1 3551 54 1.5% 1 +[V483A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.1 3551 29 0.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.1 3551 25 0.7% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.1 3551 17 0.5% 1 +[A623V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.3 3541 2303 65.0% 0 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.25.3 3541 663 18.7% 1 +[T19R,E156G,F157-,R158-,L176F,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.3 3541 146 4.1% 1 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.3 3541 45 1.3% 1 +[L5F,T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.3 3541 24 0.7% 1 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,S704L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.13 3518 1970 56.0% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.13 3518 415 11.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.13 3518 307 8.7% 1 +[T19R,E156G,F157-,R158-,I210-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.13 3518 81 2.3% 2 +[T19R,E156G,F157-,R158-,I210-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.13 3518 48 1.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,S940F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.114 3506 1957 55.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.114 3506 623 17.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.114 3506 46 1.3% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.114 3506 37 1.1% 2 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.114 3506 30 0.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,S640F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1 3483 2259 64.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1 3483 170 4.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T961M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1 3483 39 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1 3483 38 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S929T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1 3483 27 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] AY.93 3472 2750 79.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.93 3472 64 1.8% 1 +[T19R,E156G,F157-,R158-,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.93 3472 62 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,T547I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.93 3472 36 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,I818V,D950N,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.93 3472 29 0.8% 1 +[T19R,E156G,F157-,R158-,L452R,A623S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.5.1.6 3435 2334 67.9% 0 +[Q52H,F157L,F456L] (consensus) EG.5.1.6 3435 112 3.3% 1 +[Q52H,F157L,L455F,F456L] EG.5.1.6 3435 92 2.7% 1 +[Q52H,F157L,N211I,F456L] EG.5.1.6 3435 36 1.0% 1 +[Q52H,H146K,F157L,F456L]-[H146Q] EG.5.1.6 3435 35 1.0% 1 +[L5F,Q52H,F157L,F456L] HF.1 3429 2463 71.8% 0 +[E180V,K304N,T478R]-[T478K] (consensus) HF.1 3429 75 2.2% 1 +[H146K,E180V,K304N,T478R]-[H146Q,T478K] HF.1 3429 42 1.2% 1 +[G75V,E180V,K304N,T478R]-[T478K] HF.1 3429 35 1.0% 2 +[E180V,K304N,T478R,D1084N,H1101Y]-[T478K] HF.1 3429 24 0.7% 1 +[E180V,K304N,T478R]-[K417N,T478K] BA.2.86.1 3424 1999 58.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) BA.2.86.1 3424 293 8.6% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.1 3424 61 1.8% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.1 3424 35 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.1 3424 24 0.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] BQ.1.1.1 3385 1976 58.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.1 3385 189 5.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.1 3385 67 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.1 3385 58 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.1 3385 51 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.595 3380 2275 67.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.595 3380 117 3.5% 1 +[A1087G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595 3380 109 3.2% 1 +[D178G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595 3380 53 1.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595 3380 50 1.5% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HK.3.2 3358 1597 47.6% 0 +[Q14K,Q52H,L455F,F456L] (consensus) HK.3.2 3358 228 6.8% 1 +[Q14K,Q52H,L455F,F456L,Q677H] HK.3.2 3358 127 3.8% 1 +[Q14K,Q52H,N185D,L455F,F456L] HK.3.2 3358 82 2.4% 1 +[Q14K,Q52H,H146K,L455F,F456L]-[H146Q] HK.3.2 3358 64 1.9% 1 +[Q14K,Q52H,G184A,L455F,F456L] B.1.497 3317 2698 81.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.497 3317 77 2.3% 2 +[Q52H,N556K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.497 3317 50 1.5% 1 +[I1169F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.497 3317 50 1.5% 1 +[A684T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.497 3317 26 0.8% 1 +[T20N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.6.5 3313 2673 80.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.6.5 3313 38 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.6.5 3313 33 1.0% 1 +[W64L,H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.5 3313 30 0.9% 1 +[H69-,V70-,V213G,T250I,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.5 3313 25 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.85 3299 998 30.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.85 3299 798 24.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.85 3299 135 4.1% 2 +[T19R,T95I,E156G,F157-,R158-,F306L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.85 3299 99 3.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,S698A,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.85 3299 41 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,G219D,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.75.2 3286 2118 64.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BA.2.75.2 3286 45 1.4% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.2 3286 36 1.1% 1 +[K147E,W152R,F157L,I210V,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F486P,F490S] BA.2.75.2 3286 36 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.2 3286 32 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,L1186I,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.33 3277 2187 66.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.33 3277 57 1.7% 1 +[Q23K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.33 3277 40 1.2% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.33 3277 23 0.7% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.33 3277 22 0.7% 2 +[Q52H,S514F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.38 3254 1717 52.8% 0 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.38 3254 215 6.6% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.38 3254 121 3.7% 1 +[V213G,G339D,K417T,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38 3254 101 3.1% 4 +[V213G,G339D,K417T,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38 3254 99 3.0% 1 +[V213G,G339D,K417T,K444N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BF.4 3221 2471 76.7% 0 +[H69-,V70-,V213G,T259A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.4 3221 70 2.2% 1 +[H69-,V70-,V213G,T259A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.4 3221 61 1.9% 2 +[T19L,H69-,V70-,V213G,T259A,G339D,L452R,F486V,D1153N]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.4 3221 42 1.3% 1 +[H69-,V70-,V213G,T259A,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.4 3221 37 1.1% 1 +[H69-,V70-,V213G,T259A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.20 3219 2013 62.5% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) BA.2.3.20 3219 44 1.4% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478E,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] BA.2.3.20 3219 38 1.2% 1 +[M153T,N164K,M177I,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BA.2.3.20 3219 35 1.1% 1 +[M153T,N164K,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BA.2.3.20 3219 33 1.0% 1 +[M153T,N164K,V213G,H245N,Y248H,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] AY.7 3210 2526 78.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.7 3210 91 2.8% 1 +[T19R,E156G,F157-,R158-,Y265C,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7 3210 78 2.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,T747I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7 3210 57 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7 3210 45 1.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1224S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] BQ.1.3.2 3193 2342 73.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.3.2 3193 122 3.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,V1133A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.2 3193 52 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.2 3193 42 1.3% 1 +[H69-,V70-,W152R,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.2 3193 20 0.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] P.1.15 3178 2208 69.5% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.15 3178 124 3.9% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,G1085E,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.15 3178 35 1.1% 1 +[L18F,T20N,P26S,D138Y,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.15 3178 28 0.9% 1 +[L5F,L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.15 3178 23 0.7% 2 +[L18F,T20N,P25S,P26S,D138Y,R190S,K417T,E484K,T1027I,G1085E,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.15 3130 1955 62.5% 0 (consensus) XBB.1.5.15 3130 146 4.7% 2 +[N185D,F456L] XBB.1.5.15 3130 61 1.9% 1 +[H146K]-[H146Q] XBB.1.5.15 3130 49 1.6% 1 -[K417N] XBB.1.5.15 3130 45 1.4% 1 +[G181V] BQ.1.1.7 3121 2159 69.2% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.7 3121 197 6.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.7 3121 43 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,V1230M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.7 3121 25 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T1077A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.7 3121 22 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,F643L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.101 3108 1174 37.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.101 3108 760 24.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.101 3108 160 5.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.101 3108 79 2.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.101 3108 38 1.2% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.7 3094 2189 70.7% 0 (consensus) XBB.1.5.7 3094 50 1.6% 1 -[K417N] XBB.1.5.7 3094 46 1.5% 1 +[H146K]-[H146Q] XBB.1.5.7 3094 31 1.0% 2 -[R408S,S477N] XBB.1.5.7 3094 29 0.9% 2 +[H146K,D936H]-[H146Q] BA.1.1.12 3078 2700 87.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.12 3078 60 1.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,S704L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.12 3078 52 1.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,T299I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.12 3078 34 1.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,P272L,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.12 3078 21 0.7% 1 +[L54F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.5.1.6 3065 1892 61.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.6 3065 180 5.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.6 3065 160 5.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.6 3065 121 3.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.6 3065 56 1.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.2 2996 2084 69.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.2 2996 184 6.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1219C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.2 2996 113 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.2 2996 35 1.2% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.2 2996 24 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.311 2972 1143 38.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.311 2972 478 16.1% 1 +[G72R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.311 2972 309 10.4% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.311 2972 204 6.9% 1 +[S12F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.311 2972 121 4.1% 2 +[D88H,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.7 2958 2051 69.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.7 2958 302 10.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.7 2958 53 1.8% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.7 2958 18 0.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] JN.1.7 2958 17 0.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.1.1.16 2953 2628 89.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.16 2953 21 0.7% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.16 2953 16 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.16 2953 16 0.5% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.16 2953 14 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,L452M,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] EG.6.1 2925 1923 65.7% 0 +[F456L] (consensus) EG.6.1 2925 83 2.8% 1 +[F456L]-[R408S] EG.6.1 2925 58 2.0% 1 +[H146K,F456L]-[H146Q] EG.6.1 2925 54 1.8% 1 +[F456L,C1236F] EG.6.1 2925 29 1.0% 1 +[F456L,V705I] AY.70 2894 1802 62.3% 0 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.70 2894 606 20.9% 1 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.70 2894 25 0.9% 2 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.70 2894 22 0.8% 2 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R,D950N,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.70 2894 22 0.8% 1 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R,D950N,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GE.1 2882 1519 52.7% 0 +[N185I,F186-,D253G,T478R,P521S]-[G252V,T478K] (consensus) GE.1 2882 85 2.9% 1 +[M153I,N185I,F186-,D253G,T478R,P521S]-[G252V,T478K] GE.1 2882 50 1.7% 1 +[L118I,N185I,F186-,D253G,T478R,P521S]-[G252V,T478K] GE.1 2882 47 1.6% 1 +[H146K,N185I,F186-,D253G,T478R,P521S]-[H146Q,G252V,T478K] GE.1 2882 44 1.5% 1 +[E96G,N185I,F186-,D253G,T478R,P521S]-[G252V,T478K] BA.5.2.48 2872 2305 80.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.48 2872 32 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.48 2872 15 0.5% 1 +[H69-,V70-,V213G,L277F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.48 2872 10 0.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.48 2872 9 0.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] P.1.10 2858 2146 75.1% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.10 2858 225 7.9% 1 +[L18F,T20N,P26S,D138Y,Q183H,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10 2858 41 1.4% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,N606K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10 2858 32 1.1% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10 2858 24 0.8% 1 +[L18F,T20N,P26S,D138Y,R190S,T323I,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.18 2847 2164 76.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.18 2847 46 1.6% 1 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.18 2847 45 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.18 2847 40 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S939F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.18 2847 26 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] AY.30 2838 1018 35.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.30 2838 838 29.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.30 2838 178 6.3% 4 +[T19R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.30 2838 34 1.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.30 2838 28 1.0% 3 +[T19R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DY.3 2822 2432 86.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DY.3 2822 20 0.7% 1 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.3 2822 10 0.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1124V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.3 2822 9 0.3% 1 +[H69-,V70-,V83F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.3 2822 8 0.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.70 2819 1221 43.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.70 2819 689 24.4% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.70 2819 71 2.5% 2 +[H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.70 2819 68 2.4% 1 +[A1078V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.70 2819 45 1.6% 2 +[L5F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.27 2811 1675 59.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.27 2811 293 10.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.27 2811 46 1.6% 1 +[H69-,V70-,K147I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.27 2811 39 1.4% 1 +[H69-,V70-,K97T,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.27 2811 36 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D936G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.57 2809 2064 73.5% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.57 2809 297 10.6% 2 +[P26S,A222V,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.57 2809 67 2.4% 1 +[A222V,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.57 2809 22 0.8% 1 +[A222V,A575S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.57 2809 20 0.7% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.575 2801 2001 71.4% 0 +[S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.575 2801 155 5.5% 1 +[S494P,T716I,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575 2801 49 1.7% 1 +[W152R,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575 2801 40 1.4% 2 +[S494P,T716I,S735L,A893S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575 2801 36 1.3% 1 +[L5F,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.120.1 2799 1508 53.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.120.1 2799 478 17.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.1 2799 78 2.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.1 2799 39 1.4% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.1 2799 35 1.3% 1 +[T19R,L54F,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.9 2776 2131 76.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BE.9 2776 57 2.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.9 2776 43 1.5% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.9 2776 42 1.5% 1 +[H69-,V70-,F157S,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.9 2776 31 1.1% 1 +[H69-,V70-,V213G,S255F,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.5.1 2772 2222 80.2% 0 +[H69-,V70-,T76I,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.5.1 2772 53 1.9% 1 +[H69-,V70-,T76I,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.1 2772 34 1.2% 1 +[L5F,H69-,V70-,T76I,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.1 2772 31 1.1% 1 +[H69-,V70-,T76I,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.5.1 2772 22 0.8% 1 +[H69-,V70-,T76I,V213G,S255F,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.13.1 2770 2424 87.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.13.1 2770 64 2.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,Q1201K]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.13.1 2770 49 1.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.13.1 2770 29 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.13.1 2770 8 0.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,S1021F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.1.318 2755 1860 67.5% 0 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.318 2755 112 4.1% 1 +[T95I,E484K,D796H,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.318 2755 60 2.2% 1 +[T95I,E484K,D796H,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.318 2755 40 1.5% 1 +[T95I,E484K,N501T,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.318 2755 32 1.2% 2 +[T95I,E484K,D796H,A1078S,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BQ.1.1.69 2744 1840 67.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.69 2744 214 7.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.69 2744 46 1.7% 1 +[H69-,V70-,V213G,G252D,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.69 2744 33 1.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.69 2744 26 0.9% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.9.3 2720 2099 77.2% 0 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.3 2720 153 5.6% 1 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.9.3 2720 47 1.7% 1 +[W64R,M153T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.3 2720 24 0.9% 1 +[W64R,V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.3 2720 18 0.7% 1 +[W64R,V213G,G339D,Q493R,D1259H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.76 2711 1966 72.5% 0 +[V213G,Y248N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.76 2711 135 5.0% 1 +[V213G,Y248N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.76 2711 52 1.9% 4 +[V213G,Y248N,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.76 2711 38 1.4% 1 +[L5F,V213G,Y248N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.76 2711 24 0.9% 1 +[V213G,Y248N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.110 2689 1535 57.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.110 2689 593 22.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.110 2689 44 1.6% 1 +[T19R,T95I,K97R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.110 2689 36 1.3% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.110 2689 31 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,A623V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.35 2686 1973 73.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.35 2686 57 2.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.35 2686 34 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.35 2686 30 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,N460K,F486P,F490S] BA.5.2.35 2686 25 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.13 2655 1310 49.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.13 2655 703 26.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13 2655 68 2.6% 1 +[H69-,V70-,G184S,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13 2655 53 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T618K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13 2655 36 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L1244F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.2.7 2654 2203 83.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.7 2654 98 3.7% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.7 2654 76 2.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.7 2654 24 0.9% 2 +[L5F,V213G,G339D,Q493R,I1130V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.7 2654 16 0.6% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DV.7.1 2624 1709 65.1% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.7.1 2624 52 2.0% 1 +[K147E,W152R,M153I,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1 2624 47 1.8% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] DV.7.1 2624 45 1.7% 1 +[K147E,W152R,F157L,E180D,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1 2624 45 1.7% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I,D1184Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JF.1 2614 1938 74.1% 0 +[E180V,L455F,F456L,T478R]-[T478K] (consensus) JF.1 2614 80 3.1% 1 +[H146K,E180V,L455F,F456L,T478R]-[H146Q,T478K] JF.1 2614 53 2.0% 1 +[E180V,L455F,F456L,T478R,V1264L]-[T478K] JF.1 2614 49 1.9% 1 +[E180V,L455F,F456L,A475V,T478R]-[T478K] JF.1 2614 21 0.8% 2 +[Q14H,E180V,L455F,F456L,T478R,S810L]-[T478K] AY.39.1.4 2601 2272 87.4% 0 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.1.4 2601 24 0.9% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.4 2601 22 0.8% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,A222S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.4 2601 19 0.7% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,N856K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.4 2601 19 0.7% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D936Y,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116.1 2594 1460 56.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.116.1 2594 301 11.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116.1 2594 81 3.1% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116.1 2594 65 2.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116.1 2594 51 2.0% 1 +[T19R,T95I,E156G,F157-,R158-,F306L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.3 2593 736 28.4% 0 +[T19R,P26S,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.3 2593 494 19.1% 1 +[T19R,P26S,L54F,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.3 2593 359 13.8% 3 +[T19R,P26S,L54F,T95I,E156G,F157-,R158-,A262S,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.3 2593 146 5.6% 2 +[T19R,P26S,L54F,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.3 2593 99 3.8% 1 +[T19R,P26S,T95I,E156G,F157-,R158-,M177I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.13 2568 1940 75.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.13 2568 50 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.13 2568 39 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S1147L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.13 2568 29 1.1% 1 +[H69-,V70-,V213G,T250I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.13 2568 27 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T791I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.1 2565 1783 69.5% 0 +[T573I] (consensus) XBB.1.5.1 2565 43 1.7% 1 XBB.1.5.1 2565 35 1.4% 1 +[T573I]-[K417N] XBB.1.5.1 2565 33 1.3% 1 +[T478R,T573I]-[T478K] XBB.1.5.1 2565 33 1.3% 1 +[H146K,T573I]-[H146Q] BF.7.6 2562 1790 69.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.6 2562 40 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.6 2562 36 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.6 2562 34 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.6 2562 26 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.121.1 2559 1463 57.2% 0 +[T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.121.1 2559 168 6.6% 1 +[T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121.1 2559 120 4.7% 1 +[V6F,T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121.1 2559 104 4.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121.1 2559 42 1.6% 2 +[T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N,N1158D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.1.1 2559 1613 63.0% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,I670V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.1 2559 429 16.8% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.1 2559 45 1.8% 4 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.1 2559 43 1.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,I670V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.1 2559 37 1.4% 1 +[V3G,H69-,V70-,G181V,V213G,G339D,L452R,F486V,I670V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] ED.1 2558 2225 87.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) ED.1 2558 43 1.7% 1 +[H69-,V70-,T208M,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.1 2558 18 0.7% 1 +[H69-,V70-,V213G,L242F,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.1 2558 14 0.5% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.1 2558 12 0.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.49 2542 1429 56.2% 0 (consensus) XBB.1.5.49 2542 123 4.8% 1 +[T478R]-[T478K] XBB.1.5.49 2542 70 2.8% 1 -[K417N] XBB.1.5.49 2542 54 2.1% 1 +[H146K]-[H146Q] XBB.1.5.49 2542 40 1.6% 1 +[N658K] A 2499 1784 71.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A 2499 82 3.3% 3 +[A222V,D253Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A 2499 53 2.1% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A 2499 44 1.8% 3 +[H245R,R682W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] A 2499 38 1.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DV.6 2495 1849 74.1% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.6 2495 77 3.1% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,N764K] DV.6 2495 32 1.3% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I1216V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.6 2495 29 1.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,S673T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.6 2495 26 1.0% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,T678I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBB.1.16.15 2492 1683 67.5% 0 +[K147N,E180V,T478R,P521S]-[T478K] (consensus) XBB.1.16.15 2492 126 5.1% 1 +[K147N,E180V,T478R,P521S,T732I]-[T478K] XBB.1.16.15 2492 44 1.8% 1 +[K147N,E180V,T478R,P521S,S704L]-[T478K] XBB.1.16.15 2492 25 1.0% 1 +[K147N,E180V,T478R,P521S,V1228L]-[T478K] XBB.1.16.15 2492 21 0.8% 1 +[K147N,E180V,T478R,P521S]-[R408S,T478K] BA.5.3 2489 1332 53.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3 2489 260 10.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3 2489 204 8.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S1170F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3 2489 112 4.5% 1 +[H69-,V70-,V213G,G261C,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3 2489 76 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.39.1.2 2481 1363 54.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.1.2 2481 472 19.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.2 2481 69 2.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.2 2481 57 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.2 2481 40 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,A522V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.434 2480 1296 52.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.434 2480 556 22.4% 1 +[D1168G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.434 2480 62 2.5% 1 +[D1084G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.434 2480 46 1.9% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.434 2480 33 1.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.2.1 2476 1456 58.8% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.2.2.1 2476 887 35.8% 29 +[V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2.1 2476 40 1.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.2.2.1 2476 22 0.9% 25 +[V213G,G339D,Q493R,I1221T]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2.1 2476 11 0.4% 30 +[G75A,V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.107 2453 1375 56.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.107 2453 288 11.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.107 2453 57 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,E180D,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.107 2453 57 2.3% 1 +[T19R,T95I,V143F,E156G,F157-,R158-,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.107 2453 50 2.0% 6 +[L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.2.3 2453 1702 69.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.2.3 2453 138 5.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2.3 2453 127 5.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,E484V,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BQ.1.2.3 2453 70 2.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2.3 2453 27 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V,T791P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.2.3.11 2441 2112 86.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.11 2441 31 1.3% 1 +[V213G,G339D,Q493R,A570V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.11 2441 20 0.8% 1 +[V90I,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.11 2441 20 0.8% 1 +[V213G,G339D,Q493R,V622A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.11 2441 15 0.6% 1 +[V213G,G339D,Q493R,K1191N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.3.1 2439 1816 74.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.1 2439 61 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.3.1 2439 21 0.9% 1 +[K147E,W152R,F157L,G181A,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.1 2439 19 0.8% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.1 2439 17 0.7% 1 +[K147E,W152R,F157L,Q183H,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.1.14.1 2410 1673 69.4% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.14.1 2410 167 6.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.14.1 2410 53 2.2% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.14.1 2410 51 2.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.14.1 2410 36 1.5% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.29.2 2392 2156 90.1% 0 +[T19R,T95I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.29.2 2392 45 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,V308L,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.2 2392 12 0.5% 1 +[T19R,T95I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.2 2392 10 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N,Q954K]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.2 2392 8 0.3% 2 +[T19R,T95I,E156G,F157-,R158-,S254F,Q414R,L452R,P681R,D950N,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.5 2383 1924 80.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.5 2383 19 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.5 2383 12 0.5% 1 +[K147E,W152R,F157L,I210V,V213G,R214H,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.5 2383 11 0.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,P681R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,P681H] BN.1.5 2383 10 0.4% 2 +[K147E,W152R,F157L,I210V,V213G,K356T]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] AY.5.4 2376 892 37.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5.4 2376 395 16.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.4 2376 292 12.3% 1 +[T19R,D80Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.4 2376 177 7.4% 2 +[T19R,D80Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.4 2376 30 1.3% 3 +[T19R,D80Y,E156G,F157-,R158-,S162I,H245Y,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.15 2374 1535 64.7% 0 +[F486S]-[F486P] (consensus) XBB.1.15 2374 176 7.4% 1 +[F486S]-[K417N,F486P] XBB.1.15 2374 65 2.7% 1 +[F486S,V1122L]-[F486P] XBB.1.15 2374 53 2.2% 1 +[F486S]-[G252V,F486P] XBB.1.15 2374 41 1.7% 1 +[H146K,F486S]-[H146Q,F486P] B.1.466.2 2371 1354 57.1% 0 +[N439K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.466.2 2371 245 10.3% 1 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.2 2371 94 4.0% 1 +[W152R,N439K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.2 2371 34 1.4% 1 +[L5F,N439K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.2 2371 27 1.1% 1 +[N439K,P681R,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.1 2358 1378 58.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.1 2358 208 8.8% 1 +[H146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.1 2358 61 2.6% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.1 2358 36 1.5% 1 +[A783S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.1 2358 36 1.5% 2 +[I818V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24 2350 1416 60.3% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.24 2350 315 13.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24 2350 66 2.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,T859I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24 2350 63 2.7% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24 2350 43 1.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.311 2347 1952 83.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.311 2347 104 4.4% 1 +[S477I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.311 2347 21 0.9% 1 +[N125S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.311 2347 21 0.9% 1 +[Q957L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.311 2347 11 0.5% 2 +[Q52H,Q677R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.11 2336 1753 75.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.11 2336 168 7.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1016S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.11 2336 42 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.11 2336 37 1.6% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,A1016S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.11 2336 23 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H625R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.176 2306 1761 76.4% 0 +[T20I,R357K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.176 2306 281 12.2% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.176 2306 19 0.8% 1 +[L5F,T20I,R357K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.176 2306 18 0.8% 1 +[T20I,R357K,V1264M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.176 2306 17 0.7% 1 +[T20I,R357K,V433I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.63 2301 1955 85.0% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.63 2301 74 3.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,K814R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.63 2301 27 1.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.63 2301 24 1.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,S704L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.63 2301 19 0.8% 1 +[T19R,E156G,F157-,R158-,A222V,P337L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.20 2289 1627 71.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.20 2289 417 18.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A1070V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.20 2289 15 0.7% 1 +[H69-,V70-,V213G,L216F,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.20 2289 13 0.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,G1124V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.20 2289 11 0.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,F1075L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.59 2279 1145 50.2% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.59 2279 360 15.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.59 2279 69 3.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.59 2279 22 1.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,G932V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.59 2279 15 0.7% 7 +[T19R,P85T,V90D,Y91D,F92S,S94T,E156G,F157-,R158-,A222V,L452R,P681R,D950N,E1182Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DY.1 2270 1693 74.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DY.1 2270 47 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S,N1125S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.1 2270 24 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.1 2270 24 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S,E1258D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.1 2270 19 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,A570S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.10 2268 1795 79.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.10 2268 39 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.10 2268 30 1.3% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.10 2268 24 1.1% 1 +[H69-,V70-,V213G,Q271E,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.10 2268 24 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.1 2257 1485 65.8% 0 +[T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.1 2257 141 6.2% 1 +[T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.1 2257 76 3.4% 1 +[V16A,T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.1 2257 40 1.8% 2 +[T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.1 2257 30 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.2 2256 1431 63.4% 0 (consensus) FL.2 2256 52 2.3% 3 +[L141-,G142-,V143-]-[G142D] FL.2 2256 37 1.6% 1 +[T478R]-[T478K] FL.2 2256 30 1.3% 1 +[S256P] FL.2 2256 26 1.2% 1 +[H146K]-[H146Q] AY.4.9 2252 1364 60.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.9 2252 312 13.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.9 2252 57 2.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.9 2252 54 2.4% 3 +[T19R,T95I,E156G,F157-,R158-,A352S,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.9 2252 29 1.3% 2 +[T19R,T95I,E156G,F157-,R158-,A352S,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XE 2252 2051 91.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XE 2252 57 2.5% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XE 2252 17 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XE 2252 17 0.8% 1 +[V213G,H245N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XE 2252 6 0.3% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.17 2234 1478 66.2% 0 (consensus) XBB.1.5.17 2234 81 3.6% 1 +[H146K]-[H146Q] XBB.1.5.17 2234 27 1.2% 2 +[S256L,F490P]-[F490S] XBB.1.5.17 2234 25 1.1% 1 +[N556K] XBB.1.5.17 2234 23 1.0% 1 -[K417N] B.1.36.18 2227 1612 72.4% 0 +[G75R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.18 2227 60 2.7% 1 +[G75R,A684V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.18 2227 58 2.6% 1 +[G75R,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.18 2227 58 2.6% 1 +[G75R,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.18 2227 58 2.6% 1 +[G75R,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.1 2227 1360 61.1% 0 +[T95I,E154K,L452R,E484Q,P681R,Q1071H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.617.1 2227 95 4.3% 1 +[T95I,L452R,E484Q,P681R,Q1071H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.1 2227 54 2.4% 1 +[T95I,E154K,L452R,E484Q,P681R,Q1071H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.1 2227 41 1.8% 2 +[E154K,L452R,E484Q,P681R,Q1071H,H1101D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.1 2227 41 1.8% 2 +[T95I,E154K,L452R,E484Q,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.32 2224 1571 70.6% 0 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.32 2224 90 4.0% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T1120S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.32 2224 47 2.1% 1 +[H69-,V70-,M153I,V213G,T323I,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.32 2224 35 1.6% 1 +[H69-,V70-,M153I,V213G,A260T,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.32 2224 25 1.1% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BF.13 2210 1711 77.4% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.13 2210 52 2.4% 2 +[L5F,H69-,V70-,V213G,G339D,R346S,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.13 2210 37 1.7% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.13 2210 32 1.4% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.13 2210 23 1.0% 1 +[H69-,V70-,V213G,A222S,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.8.1 2206 1484 67.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.8.1 2206 162 7.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.8.1 2206 145 6.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.8.1 2206 26 1.2% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.8.1 2206 12 0.5% 2 +[+16MPLF,R21T,S50L,I68T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BQ.1.1.15 2204 1174 53.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.15 2204 298 13.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.15 2204 48 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.15 2204 45 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.15 2204 26 1.2% 1 +[H69-,V70-,E180G,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] JN.1.39 2182 1243 57.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.39 2182 297 13.6% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.39 2182 54 2.5% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.39 2182 44 2.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.39 2182 27 1.2% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] EG.5.1.8 2180 1174 53.9% 0 +[Q52H,L455F,F456L] (consensus) EG.5.1.8 2180 105 4.8% 1 +[Q52H,L455F,F456L,E654V] EG.5.1.8 2180 77 3.5% 1 +[Q52H,T95I,L455F,F456L] EG.5.1.8 2180 69 3.2% 1 +[Q52H,H146K,L455F,F456L]-[H146Q] EG.5.1.8 2180 38 1.7% 2 +[Q52H,H146K,L455F,F456L,E654V]-[H146Q] P.1.1 2179 679 31.2% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.1 2179 470 21.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.1 2179 358 16.4% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,S813N,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.1 2179 60 2.8% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,S640F,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.1 2179 56 2.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E583D,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.529 2172 191 8.8% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H] B.1.1.529 2172 41 1.9% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,L452R,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H] B.1.1.529 2172 30 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H] B.1.1.529 2172 29 1.3% 7 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H] B.1.1.529 2172 28 1.3% 10 +[T19R,A67V,H69-,V70-,T95I,V143-,Y145-,E156G,F157-,R158-,E554Q,N856K]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N764K,D796Y,N969K] BQ.1.13.1 2142 1624 75.8% 0 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.13.1 2142 34 1.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13.1 2142 32 1.5% 1 +[L5F,H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13.1 2142 26 1.2% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.13.1 2142 19 0.9% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,E780G]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.4 2137 1621 75.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.4 2137 49 2.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.4 2137 39 1.8% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.4 2137 36 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.4 2137 24 1.1% 2 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.20 2123 1482 69.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.20 2123 135 6.4% 1 +[H69-,V70-,V213G,T259I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.20 2123 126 5.9% 1 +[A67S,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.20 2123 53 2.5% 2 +[H69-,V70-,K147N,V213G,S247N,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.20 2123 19 0.9% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.57 2123 1584 74.6% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.57 2123 37 1.7% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.57 2123 37 1.7% 1 +[T19R,S98F,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.57 2123 29 1.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,P1079S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.57 2123 25 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.10 2113 1863 88.2% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.10 2113 40 1.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,Q1201K]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.10 2113 20 0.9% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.10 2113 18 0.9% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.10 2113 9 0.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.582 2112 1468 69.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.582 2112 159 7.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.582 2112 45 2.1% 2 +[L5F,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.582 2112 43 2.0% 1 +[V1164F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.582 2112 27 1.3% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.5.4 2112 1658 78.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.5.4 2112 75 3.6% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,T572S,A1020S,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.4 2112 51 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G946R,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.4 2112 36 1.7% 1 +[H69-,V70-,V213G,T299I,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.4 2112 18 0.9% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4 2106 1573 74.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.4 2106 47 2.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4 2106 38 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.4 2106 36 1.7% 1 +[H69-,V70-,G184S,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4 2106 26 1.2% 1 +[Q52H,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.82 2106 1728 82.1% 0 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.82 2106 44 2.1% 1 +[A222V,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.82 2106 30 1.4% 1 +[T95N,A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.82 2106 26 1.2% 1 +[L18F,A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.82 2106 20 0.9% 1 +[A222V,A262S,P272L,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.27 2102 1417 67.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.27 2102 192 9.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V687I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.27 2102 67 3.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.27 2102 23 1.1% 4 +[H69-,V70-,V213G,G339D,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.27 2102 19 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1184Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.5 2099 1616 77.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.5 2099 81 3.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.9.5 2099 73 3.5% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.5 2099 16 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N764K] BA.2.9.5 2099 14 0.7% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.37 2091 768 36.7% 0 +[T19R,E156G,F157-,R158-,A222V,V367L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.37 2091 340 16.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.37 2091 235 11.2% 1 +[T19R,E156G,F157-,R158-,A222V,V367L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.37 2091 164 7.8% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,Y508H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.37 2091 79 3.8% 3 +[T19R,E156G,F157-,R158-,A222V,L452R,Y508H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.10.2 2089 1754 84.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.10.2 2089 132 6.3% 31 +[R34L,A123S,V213G,R214L,G339D,A344S,+370F,A372P,S373F,T376-,A411S,V433F,G476C,Q493L,Q498L,R577L,R634L,R646L,A672S,R682L,R683L,R685L,R765L,G857C,R983L,R1091L,R1185L,D1199Y,D1260Y]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,N440K,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.10.2 2089 33 1.6% 1 +[F157L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.2 2089 25 1.2% 1 +[V213G,G339D,Q493R,S929N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.2 2089 22 1.1% 1 +[V213G,G339D,Q493R,L752F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.258.11 2082 985 47.3% 0 +[H69-,V70-,V143F,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.11 2082 595 28.6% 1 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.11 2082 131 6.3% 2 +[H69-,V70-,G261R,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.11 2082 90 4.3% 1 +[H69-,V70-,V143F,N439K,G1085A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.11 2082 52 2.5% 1 +[H69-,V70-,V143F,N439K,S673G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.2 2074 1137 54.8% 0 +[T19R,E156G,F157-,R158-,A411S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.2 2074 279 13.5% 2 +[T19R,E156G,F157-,R158-,A411S,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.2 2074 247 11.9% 1 +[T19R,E156G,F157-,R158-,A411S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.2 2074 30 1.4% 1 +[T19R,E156G,F157-,R158-,A411S,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.2 2074 25 1.2% 1 +[T19R,E156G,F157-,R158-,A411S,L452R,P681R,D950N,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.560 2072 776 37.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.560 2072 330 15.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.560 2072 88 4.2% 2 +[F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.560 2072 40 1.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.560 2072 32 1.5% 1 +[Q218H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.45 2071 1997 96.4% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.45 2071 10 0.5% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.45 2071 5 0.2% 1 +[G75V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.45 2071 5 0.2% 1 +[V83F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.45 2071 4 0.2% 1 +[D80Y,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.23 2060 778 37.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.23 2060 744 36.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.23 2060 75 3.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.23 2060 24 1.2% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.23 2060 17 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.3.7 2058 999 48.5% 0 +[K97E,V213G,G339D,Q493R,G1251V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.7 2058 495 24.1% 1 +[K97E,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.7 2058 180 8.7% 1 +[K97E,V213G,G339D,Q493R,G1251V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.7 2058 71 3.4% 2 +[K97E,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.7 2058 61 3.0% 1 +[K97E,V213G,G339D,Q493R,G1251V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.400 2048 977 47.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.400 2048 259 12.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.400 2048 179 8.7% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.400 2048 138 6.7% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.400 2048 85 4.2% 1 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.7 2044 1460 71.4% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.7 2044 242 11.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.7 2044 27 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.7 2044 23 1.1% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.7 2044 16 0.8% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.40.1 2006 1527 76.1% 0 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.40.1 2006 102 5.1% 1 +[M177V,V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.40.1 2006 39 1.9% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.40.1 2006 23 1.1% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.40.1 2006 22 1.1% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,K417N,V445P,G446S,N460K,F486P,F490S] GS.4.1 2001 1322 66.1% 0 +[N185D,D253G,T478R,P521S]-[G252V,T478K] (consensus) GS.4.1 2001 39 1.9% 1 +[N185D,D253G,T478R,P521S,P561S]-[G252V,T478K] GS.4.1 2001 33 1.6% 1 +[H146K,N185D,D253G,T478R,P521S]-[H146Q,G252V,T478K] GS.4.1 2001 29 1.4% 1 +[N185D,D253G,T478R,P521S]-[T19I,G252V,T478K] GS.4.1 2001 24 1.2% 1 +[N185D,D253G,T478R,P521S,Q1201K]-[G252V,T478K] AY.92 1992 1065 53.5% 0 +[T19R,T95I,E156G,F157-,R158-,D178N,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.92 1992 206 10.3% 1 +[T19R,T95I,E156G,F157-,R158-,D178N,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.92 1992 155 7.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.92 1992 59 3.0% 1 +[T19R,T95I,E156G,F157-,R158-,D178N,L242F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.92 1992 38 1.9% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.1 1991 1714 86.1% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.23.1 1991 45 2.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1230L,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.1 1991 26 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,E1188D,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.1 1991 13 0.7% 3 +[T19R,L452R,P681R,D950N,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.1 1991 9 0.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,P1162S,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GK.1 1975 453 22.9% 0 +[L455F,F456L,S704L] GK.1 1975 332 16.8% 2 +[L455F,F456L,A475V,E554K,S704L] GK.1 1975 131 6.6% 1 +[L455F,F456L,A475V,S704L] (consensus) GK.1 1975 92 4.7% 2 +[N185D,L455F,F456L,A475V,S704L] GK.1 1975 55 2.8% 1 +[F186L,L455F,F456L,S704L] AE.8 1965 1714 87.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.8 1965 16 0.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.8 1965 14 0.7% 1 +[I1216L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.8 1965 13 0.7% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.8 1965 11 0.6% 1 +[V736I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.36 1948 1206 61.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.36 1948 506 26.0% 1 +[P26S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.36 1948 33 1.7% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.36 1948 22 1.1% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.36 1948 21 1.1% 2 +[P26S,Q1201K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.16.17 1937 657 33.9% 0 +[E180V,K182Q,F456L,T478R,E554K,A701V]-[T478K] XBB.1.16.17 1937 609 31.4% 3 +[E180V,T478R,E554K]-[T478K] XBB.1.16.17 1937 110 5.7% 2 +[E180V,F456L,T478R,E554K]-[T478K] (consensus) XBB.1.16.17 1937 41 2.1% 1 +[L176F,E180V,K182Q,F456L,T478R,E554K,A701V]-[T478K] XBB.1.16.17 1937 34 1.8% 4 +[H146K,E180V,T478R,E554K]-[H146Q,T478K] BA.5.1.7 1934 1625 84.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.7 1934 47 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.7 1934 34 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.7 1934 17 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1101Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.7 1934 10 0.5% 1 +[S12F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.317 1929 687 35.6% 0 +[D138Y,A522S,Q675R,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.317 1929 385 20.0% 5 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.317 1929 83 4.3% 1 +[D138Y,Q675R,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.317 1929 57 3.0% 1 +[D138Y,A222V,A522S,Q675R,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.317 1929 57 3.0% 3 +[A522S,Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EF.1 1923 1321 68.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EF.1 1923 77 4.0% 1 +[H69-,V70-,E132Q,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1 1923 45 2.3% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1 1923 30 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EF.1 1923 16 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q836L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BF.2 1922 1498 77.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.2 1922 53 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.2 1922 31 1.6% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.2 1922 23 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.2 1922 22 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1122L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.48 1913 1659 86.7% 0 +[V213G,Y248S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.48 1913 63 3.3% 1 +[V213G,Y248S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.48 1913 18 0.9% 1 +[V213G,Y248S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.48 1913 7 0.4% 2 +[V83F,V213G,Y248S,G339D,Q493R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.48 1913 6 0.3% 1 +[V213G,Y248S,G339D,Q493R,G1171S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.517 1910 922 48.3% 0 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.517 1910 322 16.9% 1 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.517 1910 160 8.4% 2 +[N501T,Q613H,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.517 1910 92 4.8% 1 +[N501T,V1133A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.517 1910 52 2.7% 1 +[N501T,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.79 1908 1063 55.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.79 1908 209 11.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.79 1908 25 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.79 1908 21 1.1% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.79 1908 19 1.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CL.1 1906 1137 59.7% 0 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CL.1 1906 62 3.3% 5 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CL.1 1906 47 2.5% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] CL.1 1906 47 2.5% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N764K] CL.1 1906 35 1.8% 2 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N764K,D796Y] FL.5 1899 1119 58.9% 0 (consensus) FL.5 1899 37 1.9% 1 +[T478R]-[T478K] FL.5 1899 32 1.7% 1 +[H146K]-[H146Q] FL.5 1899 28 1.5% 1 +[I651V] FL.5 1899 17 0.9% 1 +[T29I] BA.2.6 1893 1459 77.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.6 1893 77 4.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.6 1893 64 3.4% 1 +[V213G,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.6 1893 48 2.5% 1 +[I210V,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.6 1893 30 1.6% 1 +[V213G,G339D,Q493R,D1259H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.561 1887 1188 63.0% 0 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.561 1887 412 21.8% 1 +[D138Y,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.561 1887 18 1.0% 3 +[D138Y,S939F,V1230A,T1238I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.561 1887 16 0.8% 2 +[D138Y,D178E,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.561 1887 11 0.6% 1 +[D138Y,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.18 1880 1459 77.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.18 1880 47 2.5% 1 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.18 1880 30 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.18 1880 17 0.9% 1 +[H69-,V70-,V159I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.18 1880 17 0.9% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.2 1876 966 51.5% 0 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.2 1876 453 24.1% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.2 1876 41 2.2% 2 +[H69-,V70-,N99D,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.2 1876 35 1.9% 1 +[H69-,V70-,H146-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.2 1876 25 1.3% 2 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,D1260H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] P.1.16 1869 1440 77.0% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.16 1869 38 2.0% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E471Q,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.16 1869 29 1.6% 1 +[L18F,T20N,P26S,D138Y,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.16 1869 22 1.2% 1 +[L5F,L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.16 1869 21 1.1% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,K528I,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.25 1859 1102 59.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.25 1859 97 5.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25 1859 90 4.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.25 1859 51 2.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T791A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25 1859 49 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.5.2.19 1853 1238 66.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.19 1853 95 5.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1083Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.19 1853 83 4.5% 4 +[H69-,V70-,L179F,G339D,N450D,L452R,F486V,F1075L]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.19 1853 44 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.19 1853 34 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1127A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.41 1838 747 40.6% 0 +[T19R,E156G,F157-,R158-,A262S,L452R,S477I,P681R,D950N,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.41 1838 509 27.7% 1 +[T19R,E156G,F157-,R158-,A262S,L452R,S477I,P681R,D950N,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.41 1838 32 1.7% 1 +[T19R,E156G,F157-,R158-,A262S,L452R,S477I,Q613H,P681R,D950N,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.41 1838 25 1.4% 2 +[T19R,E156G,F157-,R158-,L452R,S477I,P681R,D950N,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.41 1838 25 1.4% 1 +[T19R,E156G,F157-,R158-,A262S,L452R,S477I,T678I,P681R,D950N,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.37 1836 1138 62.0% 0 +[K1045R] (consensus) XBB.1.5.37 1836 67 3.6% 1 +[F456L,K1045R] XBB.1.5.37 1836 45 2.5% 1 +[K1045R]-[K417N] XBB.1.5.37 1836 28 1.5% 1 +[H146K,K1045R]-[H146Q] XBB.1.5.37 1836 22 1.2% 1 +[T478R,K1045R]-[T478K] BQ.1.3.1 1830 1078 58.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.3.1 1830 138 7.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.1 1830 58 3.2% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.1 1830 46 2.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.1 1830 40 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XAZ 1825 1331 72.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAZ 1825 63 3.5% 1 +[H69-,V70-,P82L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAZ 1825 44 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAZ 1825 37 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] XAZ 1825 30 1.6% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.307 1820 1270 69.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.307 1820 335 18.4% 1 +[G261V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.307 1820 28 1.5% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.307 1820 17 0.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.307 1820 17 0.9% 1 +[C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.32 1817 1102 60.6% 0 (consensus) XBB.1.5.32 1817 237 13.0% 1 +[T883I] XBB.1.5.32 1817 38 2.1% 1 +[D796H]-[D796Y] XBB.1.5.32 1817 21 1.2% 6 -[R408S,K417N,N440K,V445P,G446S,N460K] XBB.1.5.32 1817 19 1.0% 1 +[L335F] JD.1.1.1 1805 1259 69.8% 0 +[Y248H,L455F,F456L,A475V] (consensus) JD.1.1.1 1805 24 1.3% 1 +[Q14H,Y248H,L455F,F456L,A475V] JD.1.1.1 1805 21 1.2% 1 +[H146K,Y248H,L455F,F456L,A475V]-[H146Q] JD.1.1.1 1805 18 1.0% 1 +[Y248H,L455F,F456L,A475V,E554K] JD.1.1.1 1805 17 0.9% 1 +[L5F,Y248H,L455F,F456L,A475V] BQ.1.1.45 1798 1222 68.0% 0 +[H69-,V70-,V213G,Y248D,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.45 1798 34 1.9% 1 +[H69-,V70-,V213G,Y248D,G339D,K444T,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.45 1798 24 1.3% 1 +[H69-,V70-,V213G,Y248D,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.45 1798 18 1.0% 1 +[H69-,V70-,V213G,Y248D,G339D,K444T,G446V,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.45 1798 17 0.9% 1 +[H69-,V70-,V213G,Y248D,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,V445P,G446S,F486P,F490S] XBB.2.3.2 1797 1064 59.2% 0 +[G184V,D253G,P521S]-[G252V] (consensus) XBB.2.3.2 1797 62 3.5% 1 +[K147N,G184V,D253G,P521S]-[G252V] XBB.2.3.2 1797 39 2.2% 1 +[H146K,G184V,D253G,P521S]-[H146Q,G252V] XBB.2.3.2 1797 22 1.2% 1 +[L5F,G184V,D253G,P521S]-[G252V] XBB.2.3.2 1797 20 1.1% 1 +[G184V,D253G,P521S,S929T]-[G252V] B.1.1.25 1795 1001 55.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.25 1795 192 10.7% 1 +[P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.25 1795 126 7.0% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.25 1795 15 0.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.25 1795 14 0.8% 1 +[V6I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.8 1792 1038 57.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.8 1792 395 22.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.8 1792 20 1.1% 1 +[H69-,V70-,K150N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.8 1792 15 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.8 1792 14 0.8% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.5.2.23 1787 1263 70.7% 0 +[H69-,V70-,Y145H,V213G,S255F,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.23 1787 89 5.0% 1 +[H69-,V70-,V213G,S255F,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.23 1787 62 3.5% 1 +[H69-,V70-,Y145H,V213G,S255F,G339D,V445A,L452R,F486V,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.23 1787 29 1.6% 1 +[H69-,V70-,Y145H,V213G,S255F,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.23 1787 22 1.2% 1 +[H69-,V70-,Y145H,V213G,S255F,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.5.2.18 1785 1066 59.7% 0 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.18 1785 70 3.9% 1 +[H69-,V70-,L212S,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.18 1785 65 3.6% 2 +[H69-,V70-,H146-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.18 1785 36 2.0% 2 +[H69-,V70-,G181V,V213G,G339D,K444R,L452R,F486V,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.18 1785 29 1.6% 1 +[H69-,V70-,V213G,G339D,K444R,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.34.1.1 1785 858 48.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.34.1.1 1785 197 11.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1.1 1785 106 5.9% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1.1 1785 68 3.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1.1 1785 32 1.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,A1078S,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DN.2 1784 1398 78.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.2 1784 56 3.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.2 1784 53 3.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.2 1784 21 1.2% 1 +[H69-,V70-,F186L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.2 1784 15 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BA.5.3.3 1780 1525 85.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3.3 1780 19 1.1% 1 +[H69-,V70-,Q183K,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.3 1780 16 0.9% 1 +[H69-,V70-,V213G,H245Y,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.3 1780 12 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.3 1780 9 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,K921R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.12 1776 960 54.1% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.12 1776 206 11.6% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,A1070V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.12 1776 70 3.9% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.12 1776 49 2.8% 2 +[H69-,V70-,V213G,S255F,G339D,V445A,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.12 1776 36 2.0% 2 +[H69-,V70-,N185D,V213G,G339D,V445A,L452R,F486V,A1070V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.24 1740 1055 60.6% 0 (consensus) XBB.1.5.24 1740 39 2.2% 1 +[T883I] XBB.1.5.24 1740 28 1.6% 1 +[L5F] XBB.1.5.24 1740 24 1.4% 1 -[R408S] XBB.1.5.24 1740 23 1.3% 1 +[H146K]-[H146Q] AY.116 1739 790 45.4% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.116 1739 212 12.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116 1739 192 11.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116 1739 51 2.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,V772I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116 1739 35 2.0% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.17 1737 1589 91.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.17 1737 21 1.2% 1 +[V213G,L216F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.17 1737 21 1.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.3.17 1737 14 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.17 1737 9 0.5% 1 +[V213G,G339D,Q493R,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] Q.4 1725 1378 79.9% 0 +[H69-,V70-,A570D,P681R,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) Q.4 1725 46 2.7% 1 +[H69-,V70-,R408G,A570D,P681R,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Q.4 1725 23 1.3% 1 +[H69-,V70-,A570D,P681R,T716I,S943P,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Q.4 1725 22 1.3% 1 +[H69-,V70-,V308L,A570D,P681R,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Q.4 1725 19 1.1% 1 +[L5F,H69-,V70-,A570D,P681R,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.10 1725 1208 70.0% 0 +[F456L] (consensus) XBB.1.5.10 1725 44 2.6% 1 +[F456L,I569V] XBB.1.5.10 1725 35 2.0% 1 +[H146K,F456L]-[H146Q] XBB.1.5.10 1725 35 2.0% 1 +[F456L]-[K417N] XBB.1.5.10 1725 31 1.8% 1 +[L8F,F456L] XBB.2.3.8 1724 1247 72.3% 0 +[D253G,T478R,P521S]-[G252V,T478K] (consensus) XBB.2.3.8 1724 25 1.5% 1 +[H146K,D253G,T478R,P521S]-[H146Q,G252V,T478K] XBB.2.3.8 1724 22 1.3% 1 +[D253G,S255F,T478R,P521S]-[G252V,T478K] XBB.2.3.8 1724 14 0.8% 2 +[V213D,R246K,D253G,T478R,P521S]-[V213E,G252V,T478K] XBB.2.3.8 1724 12 0.7% 1 +[D253G,F456L,T478R,P521S]-[G252V,T478K] FY.3.1 1720 662 38.5% 0 +[H146K,Y200C,I210T]-[H146Q] (consensus) FY.3.1 1720 407 23.7% 1 +[Y200C,I210T] FY.3.1 1720 65 3.8% 3 +[Y200C,I210T,L244F,H245-] FY.3.1 1720 48 2.8% 2 +[Y200C,I210T,P384H] FY.3.1 1720 38 2.2% 2 +[Y200C,I210T,Q493L] B.1.1.306 1714 779 45.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.306 1714 131 7.6% 4 +[L18F,E484K,Q675H]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.306 1714 121 7.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.306 1714 48 2.8% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.306 1714 33 1.9% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.21 1713 1282 74.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.21 1713 176 10.3% 1 +[V213G,G339D,Q493R,Q1113K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.21 1713 58 3.4% 1 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.21 1713 23 1.3% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.21 1713 22 1.3% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.2 1710 1149 67.2% 0 +[T19R,V70F,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.2 1710 272 15.9% 1 +[T19R,V70F,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.2 1710 26 1.5% 1 +[T19R,V70F,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.2 1710 22 1.3% 2 +[T19R,V70F,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.2 1710 20 1.2% 1 +[T19R,V70F,E156G,F157-,R158-,A222V,K356N,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.22 1700 1155 67.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.22 1700 145 8.5% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.22 1700 26 1.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.22 1700 22 1.3% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.22 1700 13 0.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] BA.5.1.15 1698 948 55.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.15 1698 160 9.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.15 1698 122 7.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.15 1698 48 2.8% 1 +[H69-,V70-,V213G,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.15 1698 39 2.3% 1 +[H69-,V70-,S98F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.619.1 1691 1435 84.9% 0 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.619.1 1691 66 3.9% 1 +[T20I,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619.1 1691 17 1.0% 1 +[G75V,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619.1 1691 11 0.7% 1 +[L18F,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619.1 1691 10 0.6% 1 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.40 1690 1216 72.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.40 1690 58 3.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.40 1690 58 3.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.40 1690 23 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,G1124V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.40 1690 19 1.1% 6 +[L24S,P25Y,Y28-,T29-,H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[L24-,P25-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BE.11 1673 1379 82.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.11 1673 99 5.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.11 1673 23 1.4% 1 +[H69-,V70-,G181R,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.11 1673 16 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.11 1673 9 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.577 1649 945 57.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.577 1649 119 7.2% 1 +[I834T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.577 1649 104 6.3% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.577 1649 31 1.9% 1 +[R21K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.577 1649 30 1.8% 2 +[Q52R,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.17 1638 1165 71.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.17 1638 69 4.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.17 1638 50 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.17 1638 24 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,M740I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.17 1638 18 1.1% 1 +[V16F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.8 1638 1289 78.7% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.8 1638 40 2.4% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.8 1638 17 1.0% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.8 1638 12 0.7% 1 +[V3G,H69-,V70-,W152L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.8 1638 10 0.6% 3 +[V3G,H69-,V70-,W152L,N211-,L212I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.57 1635 999 61.1% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.57 1635 89 5.4% 1 +[H69-,V70-,L176F,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.57 1635 71 4.3% 1 +[H69-,V70-,V213G,P251L,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.57 1635 39 2.4% 1 +[H69-,V70-,H146Y,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.57 1635 36 2.2% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.31 1628 910 55.9% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.31 1628 271 16.6% 1 +[V213G,G339D,Q493R,N925S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.31 1628 165 10.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.31 1628 66 4.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.31 1628 28 1.7% 2 +[H69-,V70-,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.7 1627 1160 71.3% 0 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.7 1627 85 5.2% 1 +[H69-,V70-,V213G,Y248H,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.7 1627 24 1.5% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] BA.5.2.7 1627 23 1.4% 1 +[H69-,V70-,V213G,G339Y,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.7 1627 23 1.4% 1 +[H69-,V70-,V213G,T299I,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2.1 1619 1181 72.9% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.2.1 1619 44 2.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,E554A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2.1 1619 26 1.6% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2.1 1619 20 1.2% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,T638R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2.1 1619 17 1.1% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] XBB.1.5.20 1614 979 60.7% 0 (consensus) XBB.1.5.20 1614 62 3.8% 1 +[Q954Y]-[Q954H] XBB.1.5.20 1614 42 2.6% 1 +[H146K]-[H146Q] XBB.1.5.20 1614 33 2.0% 1 -[R408S] XBB.1.5.20 1614 33 2.0% 1 -[K417N] B.1.36.17 1605 1318 82.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.17 1605 38 2.4% 1 +[R102I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.17 1605 36 2.2% 1 +[A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.17 1605 15 0.9% 1 +[V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.17 1605 10 0.6% 1 +[G946V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.1.1.1 1602 829 51.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.1.1 1602 166 10.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T859S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1.1 1602 66 4.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1.1 1602 40 2.5% 1 +[H69-,V70-,V213G,G339D,D420N,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1.1 1602 33 2.1% 1 +[H69-,V70-,V213G,T299I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.22 1602 1349 84.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.22 1602 50 3.1% 1 +[H69-,V70-,V213G,T323A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.22 1602 33 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1251V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.22 1602 21 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.22 1602 20 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.5.3 1600 979 61.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5.3 1600 282 17.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.3 1600 32 2.0% 2 +[T19R,E156G,F157-,R158-,A263V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.3 1600 30 1.9% 1 +[T19R,E156G,F157-,R158-,A263V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.3 1600 16 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.2 1597 1328 83.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.2 1597 26 1.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.2 1597 17 1.1% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.2 1597 9 0.6% 1 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.2 1597 8 0.5% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.596 1595 888 55.7% 0 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.596 1595 66 4.1% 2 +[Q677P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596 1595 60 3.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596 1595 50 3.1% 1 +[T20I,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596 1595 34 2.1% 1 +[D627H,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.13 1593 1216 76.3% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.13 1593 55 3.5% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.13 1593 37 2.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.13 1593 25 1.6% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.13 1593 17 1.1% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,V622I,A706V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.45 1588 677 42.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.45 1588 270 17.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.45 1588 126 7.9% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,P792S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.45 1588 45 2.8% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,T747I,D936N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.45 1588 30 1.9% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.16 1582 1316 83.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.16 1582 59 3.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q1208H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.16 1582 30 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1006I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.16 1582 28 1.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.16 1582 25 1.6% 1 +[H69-,V70-,V213G,D215G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.122.1 1579 700 44.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.1 1579 415 26.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.1 1579 52 3.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.1 1579 21 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I,D950N,L1203F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.1 1579 21 1.3% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I,D950N,L1049I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.75 1578 648 41.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75 1578 148 9.4% 4 +[K147E,W152R,F157L,I210V,V213G,G257S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75 1578 42 2.7% 3 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75 1578 41 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75 1578 21 1.3% 5 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] BM.1.1.3 1578 920 58.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.1.1.3 1578 47 3.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.3 1578 33 2.1% 1 +[K147E,W152R,F157L,N185T,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.3 1578 32 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,F490P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.3 1578 29 1.8% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EG.1.6 1576 926 58.8% 0 +[Q613H] (consensus) EG.1.6 1576 106 6.7% 1 +[H146K,Q613H]-[H146Q] EG.1.6 1576 53 3.4% 1 +[Q613H,V642-] EG.1.6 1576 41 2.6% 1 +[N148T,Q613H] EG.1.6 1576 35 2.2% 1 +[Q613H,G1124V] BK.1 1573 1228 78.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BK.1 1573 51 3.2% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BK.1 1573 31 2.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BK.1 1573 15 1.0% 2 +[L5F,H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BK.1 1573 12 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.21 1564 1086 69.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.21 1564 67 4.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.21 1564 32 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1267E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.21 1564 31 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.21 1564 22 1.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.55 1560 1079 69.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.55 1560 198 12.7% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.55 1560 50 3.2% 2 +[H69-,V70-,N164K,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.55 1560 31 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,E702D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.55 1560 15 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1009I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XB 1558 863 55.4% 0 +[L18R,T95I,R158S,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) XB 1558 109 7.0% 1 +[L18R,T95I,R158S,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XB 1558 48 3.1% 1 +[L18R,T95I,R158S,A688V,S735A,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XB 1558 39 2.5% 1 +[L18R,T95I,R158S,A688V,S735A,T1027I,Y1206F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XB 1558 28 1.8% 2 +[L18R,T95I,R158S,E484Q,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.40 1557 1279 82.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.40 1557 29 1.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.40 1557 24 1.5% 1 +[A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.40 1557 20 1.3% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.40 1557 14 0.9% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.94 1557 586 37.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.94 1557 543 34.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.94 1557 65 4.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.94 1557 54 3.5% 2 +[T19R,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.94 1557 28 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,A475V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.38 1553 1217 78.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.38 1553 83 5.3% 1 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38 1553 31 2.0% 1 +[H69-,V70-,D111N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38 1553 21 1.4% 2 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V,K1073N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38 1553 20 1.3% 1 +[H69-,V70-,V213G,V308L,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.10 1548 906 58.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BE.10 1548 93 6.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.10 1548 46 3.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BE.10 1548 39 2.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.10 1548 35 2.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,F486P,F490S] B.1.128 1543 1224 79.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.128 1543 142 9.2% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.128 1543 60 3.9% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.128 1543 21 1.4% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.128 1543 15 1.0% 2 +[P809S,G1085E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.53 1536 688 44.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.53 1536 410 26.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.53 1536 42 2.7% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.53 1536 24 1.6% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.53 1536 18 1.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,C1253F]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.39 1529 562 36.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.39 1529 395 25.8% 1 +[S673T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.39 1529 125 8.2% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.39 1529 55 3.6% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.39 1529 37 2.4% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.2.2 1527 1041 68.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.2 1527 108 7.1% 1 +[K147E,W152R,F157L,I210V,V213G,A222V,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.2 1527 18 1.2% 1 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.2 1527 16 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.2 1527 15 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] CH.1.1.2 1525 1079 70.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.2 1525 36 2.4% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.2 1525 31 2.0% 1 +[I68T,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.2 1525 31 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P809Q,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.2 1525 21 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T549I,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.39.2 1517 870 57.4% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.2 1517 333 22.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.2 1517 22 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,V635A,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.2 1517 20 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.2 1517 15 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.42 1510 698 46.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.42 1510 342 22.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.42 1510 98 6.5% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.42 1510 50 3.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] JN.1.42 1510 18 1.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] AY.4.4 1505 844 56.1% 0 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.4 1505 185 12.3% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.4 1505 30 2.0% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,Q853H,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.4 1505 25 1.7% 1 +[L5F,T19R,G75V,T95I,E156G,F157-,R158-,L452R,P681R,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.4 1505 23 1.5% 2 +[L5F,T19R,G75V,T95I,E156G,F157-,R158-,L452R,P681R,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.10.1 1505 1073 71.3% 0 +[H69-,V70-,H146L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.10.1 1505 148 9.8% 2 +[H69-,V70-,Y145L,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10.1 1505 19 1.3% 1 +[H69-,V70-,H146L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.10.1 1505 15 1.0% 1 +[H66Y,H69-,V70-,H146L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10.1 1505 12 0.8% 1 +[H69-,V70-,H146L,V213G,G339D,K444T,L452R,F486V,A1020V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.3.2 1500 1225 81.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3.2 1500 47 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.3.2 1500 29 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BA.5.3.2 1500 17 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.2 1500 8 0.5% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.177.35 1497 1158 77.4% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.35 1497 68 4.5% 1 +[A222V,I410V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.35 1497 60 4.0% 1 +[L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.35 1497 27 1.8% 1 +[A222V]-[L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.35 1497 17 1.1% 1 +[A222V,C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.106 1494 525 35.1% 0 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.106 1494 224 15.0% 1 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.106 1494 101 6.8% 1 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R,D950N,A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.106 1494 54 3.6% 2 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R,D950N,A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.106 1494 28 1.9% 2 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.10 1491 1278 85.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.10 1491 41 2.7% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.10 1491 12 0.8% 2 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.10 1491 12 0.8% 2 +[T19R,T95I,E156G,F157-,R158-,A243-,L244-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.10 1491 12 0.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.68 1487 976 65.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.68 1487 158 10.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.68 1487 64 4.3% 1 +[V36I,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.68 1487 17 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,M1237T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.68 1487 16 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E554K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1.1 1481 1100 74.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EF.1.1 1481 53 3.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1.1 1481 32 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EF.1.1 1481 22 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,G446R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1.1 1481 16 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] JN.2 1480 970 65.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.2 1480 101 6.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2 1480 30 2.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2 1480 15 1.0% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2 1480 14 0.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BQ.1.1.22 1475 1196 81.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.22 1475 20 1.4% 1 +[H69-,V70-,V213G,A260V,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.22 1475 20 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.22 1475 15 1.0% 1 +[H69-,V70-,W152L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.22 1475 13 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] A.2.5 1473 573 38.9% 0 +[L141-,G142-,V143-,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2.5 1473 80 5.4% 4 +[L141-,G142-,V143-,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5 1473 75 5.1% 3 +[D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5 1473 43 2.9% 1 +[L141-,G142-,V143-,D215A,+215AGY,L452R,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5 1473 32 2.2% 2 +[L141-,G142-,V143-,D215A,+215AGY,L452R,T739I,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.36 1470 1136 77.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.36 1470 64 4.4% 1 +[H69-,V70-,V213G,Q271E,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.36 1470 49 3.3% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.36 1470 15 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.36 1470 13 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.1.298 1460 980 67.1% 0 +[H69-,V70-,Y453F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.298 1460 148 10.1% 1 +[H69-,V70-,Y453F,S1147L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.298 1460 108 7.4% 2 +[Y453F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.298 1460 30 2.1% 3 +[L5F,H69-,V70-,Y453F,N751Y,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.298 1460 18 1.2% 1 +[H69-,V70-,Y453F,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.609 1459 770 52.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.609 1459 289 19.8% 3 +[L5F,L176F,T478R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.609 1459 35 2.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.609 1459 17 1.2% 3 +[G75V,Q779R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.609 1459 15 1.0% 1 +[N679S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.2.3 1458 821 56.3% 0 (consensus) FL.2.3 1458 224 15.4% 1 +[H146K]-[H146Q] FL.2.3 1458 29 2.0% 1 +[F456L] FL.2.3 1458 23 1.6% 1 +[V642G] FL.2.3 1458 18 1.2% 2 +[H146K,P521S]-[H146Q] BA.5.2.16 1455 1019 70.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.16 1455 36 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.16 1455 35 2.4% 2 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.16 1455 23 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.16 1455 23 1.6% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.41 1451 888 61.2% 0 +[H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.41 1451 63 4.3% 1 +[H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V,I931V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.41 1451 55 3.8% 1 +[H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.41 1451 46 3.2% 1 +[L5F,H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.41 1451 43 3.0% 1 +[H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.48 1449 964 66.5% 0 (consensus) XBB.1.5.48 1449 48 3.3% 1 -[K417N] XBB.1.5.48 1449 35 2.4% 1 +[H146K]-[H146Q] XBB.1.5.48 1449 23 1.6% 1 +[T478R]-[T478K] XBB.1.5.48 1449 18 1.2% 1 +[N148T] B.1.279 1441 701 48.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.279 1441 317 22.0% 1 +[L1224F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.279 1441 268 18.6% 2 +[L18F,L1224F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.279 1441 43 3.0% 1 +[Y28H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.279 1441 16 1.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FD.2 1430 957 66.9% 0 +[H146K]-[H146Q] (consensus) FD.2 1430 145 10.1% 1 FD.2 1430 13 0.9% 1 +[H146K]-[Y144-,H146Q] FD.2 1430 13 0.9% 1 +[H146K,T307I]-[H146Q] FD.2 1430 12 0.8% 1 +[V70G,H146K]-[H146Q] FD.1.1 1430 1003 70.1% 0 +[F456L] (consensus) FD.1.1 1430 36 2.5% 1 +[H146K,F456L]-[H146Q] FD.1.1 1430 30 2.1% 1 +[L5F,F456L] FD.1.1 1430 22 1.5% 1 +[R102G,F456L] FD.1.1 1430 18 1.3% 1 +[F456L,P812L] XBB.1.16.2 1429 878 61.4% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.2 1429 82 5.7% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.2 1429 30 2.1% 1 +[E180V,T478R]-[K417N,T478K] XBB.1.16.2 1429 24 1.7% 1 +[L5I,E180V,T478R]-[T478K] XBB.1.16.2 1429 15 1.0% 1 +[E180V,N317S,T478R]-[T478K] B.1.623 1428 733 51.3% 0 +[S494P,K854N,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.623 1428 406 28.4% 1 +[S494P,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.623 1428 35 2.5% 1 +[T385I,S494P,K854N,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.623 1428 33 2.3% 2 +[T95I,S494P,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.623 1428 17 1.2% 2 +[S494P,T678I,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BF.39 1426 1108 77.7% 0 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.39 1426 66 4.6% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.39 1426 26 1.8% 1 +[H69-,V70-,G181V,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.39 1426 12 0.8% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.39 1426 12 0.8% 2 +[H69F,V70-,S71-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.3.5 1426 971 68.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.5 1426 71 5.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E471Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.5 1426 26 1.8% 2 +[H69-,V70-,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.5 1426 22 1.5% 1 +[G75S,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.5 1426 16 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.5.1.34 1416 1002 70.8% 0 +[H69-,V70-,K147-,N149-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.34 1416 185 13.1% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.34 1416 50 3.5% 1 +[H69-,V70-,K147-,N149-,V213G,G339D,L452R,F486V,P1162S,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.34 1416 30 2.1% 1 +[H69-,V70-,K147-,N149-,V213G,L216F,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.34 1416 17 1.2% 1 +[H69-,V70-,K147-,N149-,V213G,G339D,L452R,F486V,P1162S,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.42.2 1415 917 64.8% 0 +[Q613H] (consensus) XBB.1.42.2 1415 62 4.4% 1 +[G181A,Q613H] XBB.1.42.2 1415 22 1.6% 1 +[M177I,Q613H] XBB.1.42.2 1415 21 1.5% 1 +[H146K,Q613H]-[H146Q] XBB.1.42.2 1415 20 1.4% 1 +[L452R,Q613H] B.1.110.3 1413 1098 77.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.110.3 1413 52 3.7% 1 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110.3 1413 35 2.5% 1 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110.3 1413 17 1.2% 1 +[I210V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110.3 1413 13 0.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.33 1400 935 66.8% 0 (consensus) XBB.1.5.33 1400 55 3.9% 1 +[R237K] XBB.1.5.33 1400 32 2.3% 1 +[T883I] XBB.1.5.33 1400 25 1.8% 1 +[H146K]-[H146Q] XBB.1.5.33 1400 23 1.6% 1 -[K417N] AY.43.4 1397 277 19.8% 0 +[T19R,E156G,F157-,R158-,K356R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.4 1397 271 19.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.4 1397 218 15.6% 1 +[T19R,E156G,F157-,R158-,K356R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.4 1397 207 14.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.4 1397 80 5.7% 2 +[T19R,E156G,F157-,R158-,K356R,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.29 1392 631 45.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.29 1392 141 10.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.29 1392 27 1.9% 1 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.29 1392 19 1.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.36.29 1392 14 1.0% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.621.1 1386 997 71.9% 0 +[T95I,+143T,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.621.1 1386 61 4.4% 1 +[T95I,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621.1 1386 23 1.7% 2 +[T95I,Y144S,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621.1 1386 20 1.4% 1 +[T95I,+143T,Y144S,Y145N,R346K,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621.1 1386 16 1.2% 3 +[T95I,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.1.1.11 1386 865 62.4% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.11 1386 115 8.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.11 1386 86 6.2% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.11 1386 37 2.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.11 1386 22 1.6% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] B.1.177.44 1384 1104 79.8% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.44 1384 45 3.3% 1 +[S98F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.44 1384 25 1.8% 1 +[A222V,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.44 1384 23 1.7% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.44 1384 12 0.9% 1 +[L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DL.1 1382 756 54.7% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) DL.1 1382 80 5.8% 1 +[H69-,V70-,K147N,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DL.1 1382 51 3.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DL.1 1382 41 3.0% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DL.1 1382 38 2.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.43 1382 1067 77.2% 0 +[H69-,V70-,K147Q,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BA.5.2.43 1382 35 2.5% 1 +[H69-,V70-,K147Q,V213G,G339D,G446D,L452R,F486V,L1265P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.43 1382 17 1.2% 1 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.43 1382 13 0.9% 3 +[H69-,V70-,E154D,V213G,G339D,G446D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.43 1382 9 0.7% 1 +[V62L,H69-,V70-,K147Q,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.1.19 1381 957 69.3% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.19 1381 64 4.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.19 1381 59 4.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.19 1381 46 3.3% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.19 1381 23 1.7% 4 +[H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.565 1377 890 64.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.565 1377 186 13.5% 1 +[A1070S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.565 1377 29 2.1% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.565 1377 25 1.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.565 1377 21 1.5% 1 +[E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.2 1377 999 72.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.2 1377 48 3.5% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.2 1377 35 2.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1176F,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.2 1377 22 1.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.2 1377 15 1.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] AY.38 1374 304 22.1% 0 +[T19R,E156G,F157-,R158-,A222V,T250S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.38 1374 189 13.8% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.38 1374 174 12.7% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.38 1374 149 10.8% 3 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.38 1374 97 7.1% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.35 1370 1056 77.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.35 1370 35 2.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.35 1370 31 2.3% 1 +[H69-,V70-,F157L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.35 1370 23 1.7% 1 +[H69-,V70-,V213G,A260T,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.35 1370 19 1.4% 1 +[H69-,V70-,G184D,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FU.2 1370 724 52.8% 0 +[E180V,T478R,T547I]-[T478K] (consensus) FU.2 1370 89 6.5% 1 +[E180V,T478R,T547I,E554K]-[T478K] FU.2 1370 48 3.5% 1 +[H146K,E180V,T478R,T547I]-[H146Q,T478K] FU.2 1370 41 3.0% 2 +[E180V,T478R,T547I,A668S,A845S]-[T478K] FU.2 1370 20 1.5% 1 +[E180V,V445S,T478R,T547I]-[V445P,T478K] XBB.1.5.72 1367 864 63.2% 0 +[F456L] (consensus) XBB.1.5.72 1367 26 1.9% 1 +[H146K,F456L]-[H146Q] XBB.1.5.72 1367 24 1.8% 1 +[F456L,P812S] XBB.1.5.72 1367 22 1.6% 3 +[Y266F,K356T,F456L,T572I] XBB.1.5.72 1367 21 1.5% 1 +[F456L,G946R] AY.62 1364 620 45.5% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.62 1364 334 24.5% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.62 1364 36 2.6% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,N978S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.62 1364 33 2.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,G946V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.62 1364 32 2.3% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.13 1350 707 52.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.13 1350 164 12.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.13 1350 62 4.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S939F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.13 1350 31 2.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.13 1350 26 1.9% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I651V,T1066N]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.232 1348 667 49.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.232 1348 402 29.8% 1 +[L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.232 1348 63 4.7% 1 +[R346K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.232 1348 36 2.7% 1 +[A475S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.232 1348 9 0.7% 2 +[L452R,G639S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.4 1348 1210 89.8% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.4 1348 32 2.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.4 1348 13 1.0% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.4 1348 11 0.8% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.4 1348 10 0.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,H625R,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BG.5 1347 1092 81.1% 0 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BG.5 1347 37 2.7% 1 +[V213G,G339D,L452Q,Q493R,S704L,T1077A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.5 1347 35 2.6% 1 +[F32L,V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.5 1347 22 1.6% 1 +[F157L,V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.5 1347 12 0.9% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.51 1332 874 65.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.51 1332 124 9.3% 1 +[H69-,V70-,W152R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.51 1332 56 4.2% 1 +[H69-,V70-,S98F,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.51 1332 30 2.3% 1 +[H69-,V70-,V213G,T250I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.51 1332 24 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BN.1.3.6 1331 790 59.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.6 1331 42 3.2% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.6 1331 35 2.6% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.6 1331 33 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.6 1331 28 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V1122M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] AY.68 1330 675 50.8% 0 +[T19R,E156G,F157-,R158-,A222V,D253A,L452R,P681R,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.68 1330 220 16.5% 1 +[T19R,E156G,F157-,R158-,A222V,D253A,L452R,P681R,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.68 1330 53 4.0% 1 +[T19R,E156G,F157-,R158-,A222V,D253A,L452R,P681R,P809S,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.68 1330 33 2.5% 1 +[T19R,E156G,F157-,R158-,A222V,D253A,L452R,P681R,G885S,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.68 1330 31 2.3% 1 +[T19R,E156G,F157-,R158-,N211K,A222V,D253A,L452R,P681R,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.31 1325 958 72.3% 0 (consensus) XBB.1.5.31 1325 48 3.6% 1 +[M153V] XBB.1.5.31 1325 18 1.4% 1 +[H146K]-[H146Q] XBB.1.5.31 1325 17 1.3% 1 +[D1153Y] XBB.1.5.31 1325 14 1.1% 1 +[A701T] AY.7.2 1324 565 42.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.7.2 1324 393 29.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.2 1324 39 2.9% 1 +[V16F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.2 1324 21 1.6% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.2 1324 19 1.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,G1219C,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Q.2 1318 957 72.6% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.2 1318 58 4.4% 1 +[H69-,V70-,P272L,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.2 1318 50 3.8% 1 +[H69-,V70-,H245Y,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.2 1318 49 3.7% 2 +[A67V,H69-,V70-,A570D,T716I,I794T,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.2 1318 38 2.9% 1 +[H69-,V70-,A570D,T716I,I794T,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BN.1.2.3 1314 874 66.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.3 1314 35 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N481K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.3 1314 33 2.5% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.3 1314 27 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.3 1314 20 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] B.1.177.54 1313 1080 82.3% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.54 1313 51 3.9% 1 +[L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.54 1313 19 1.4% 1 +[A222V,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.54 1313 18 1.4% 2 +[A222V,T859I,V860I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.54 1313 14 1.1% 1 +[A222V,S813I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.90 1303 881 67.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.90 1303 213 16.3% 1 +[T19R,E156G,F157-,R158-,P174S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.90 1303 26 2.0% 2 +[T19R,E156G,F157-,R158-,P174S,L452R,P681R,D950N,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.90 1303 23 1.8% 1 +[V16I,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.90 1303 16 1.2% 1 +[T19R,E156G,F157-,R158-,S256L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.75.5 1303 753 57.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75.5 1303 56 4.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.5 1303 45 3.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,R346S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.5 1303 43 3.3% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F490V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.5 1303 24 1.8% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] FL.15 1302 650 49.9% 0 +[F456L] (consensus) FL.15 1302 113 8.7% 1 +[Q14H,F456L] FL.15 1302 42 3.2% 1 +[F456L,R1014K] FL.15 1302 24 1.8% 2 +[H146K,I197V,F456L]-[H146Q] FL.15 1302 23 1.8% 1 +[F186S,F456L] EG.2 1302 651 50.0% 0 +[T478R]-[T478K] (consensus) EG.2 1302 87 6.7% 2 +[T478R,Q613H,A852S]-[T478K] EG.2 1302 30 2.3% 1 +[T478R]-[K417N,T478K] EG.2 1302 24 1.8% 1 +[N185S,T478R]-[T478K] EG.2 1302 23 1.8% 1 +[F186L,T478R]-[T478K] AY.65 1299 456 35.1% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.65 1299 268 20.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.65 1299 59 4.5% 2 +[T19R,E156G,F157-,R158-,A222V,D228H,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.65 1299 51 3.9% 4 +[L5F,T19R,E156G,F157-,R158-,A222V,L452R,P681R,P809S,D950N,V1176F,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.65 1299 43 3.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.3 1292 573 44.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.3 1292 190 14.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.3 1292 115 8.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.3 1292 46 3.6% 1 +[T19R,W64C,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.3 1292 20 1.5% 2 +[T19R,W64C,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.5 1288 549 42.6% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.5 1288 263 20.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.5 1288 79 6.1% 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.5 1288 22 1.7% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.5 1288 15 1.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] B.1.1.291 1285 1122 87.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.291 1285 28 2.2% 1 +[Q52L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.291 1285 13 1.0% 1 +[Q580K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.291 1285 11 0.9% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.291 1285 11 0.9% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.61 1283 882 68.7% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.61 1283 120 9.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.61 1283 42 3.3% 1 +[T19R,P85S,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.61 1283 17 1.3% 2 +[T19R,P85S,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.61 1283 14 1.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.369 1282 1051 82.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.369 1282 54 4.2% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.369 1282 30 2.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.369 1282 22 1.7% 2 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.369 1282 16 1.2% 1 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.22 1282 1050 81.9% 0 +[F186S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.22 1282 115 9.0% 1 +[F186S,V213G,Y248H,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.22 1282 25 2.0% 1 +[F186S,V213G,G339D,Q493R,A924S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.22 1282 13 1.0% 1 +[F186S,V213G,G339D,Q493R,I1221V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.22 1282 5 0.4% 1 +[L5F,F186S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.4 1281 977 76.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.4 1281 19 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V687L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4 1281 11 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,K444R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4 1281 10 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L1141F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4 1281 9 0.7% 1 +[T22N,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BF.7.19 1264 911 72.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.19 1264 32 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1058Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.19 1264 18 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.19 1264 15 1.2% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.19 1264 14 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] XBB.1.5.16 1261 821 65.1% 0 (consensus) XBB.1.5.16 1261 41 3.3% 1 +[S704L] XBB.1.5.16 1261 32 2.5% 1 +[F456L] XBB.1.5.16 1261 24 1.9% 1 +[E661D] XBB.1.5.16 1261 23 1.8% 1 +[H146K]-[H146Q] BA.2.12.2 1255 1152 91.8% 0 +[V213G,G339D,R357K,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.12.2 1255 12 1.0% 2 +[V213G,G339D,R357K,Q493R,S704L,N1187D,C1236F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.2 1255 10 0.8% 1 +[V213G,G339D,R357K,Q493R,S704L,A783V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.2 1255 6 0.5% 1 +[V213G,G339D,R357K,Q493R,S704L,K1255R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.2 1255 5 0.4% 1 +[V213G,S255F,G339D,R357K,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.67 1255 871 69.4% 0 +[H69-,V70-,L176F,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.67 1255 54 4.3% 1 +[H69-,V70-,L176F,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.67 1255 30 2.4% 1 +[H69-,V70-,L176F,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.67 1255 26 2.1% 1 +[H69-,V70-,L176F,V213G,G339D,K444T,L452R,F486V,K1154R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.67 1255 20 1.6% 1 +[H69-,V70-,L176F,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.2.75.1 1254 664 53.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75.1 1254 49 3.9% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.1 1254 39 3.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.1 1254 15 1.2% 3 +[K147E,W152R,F157L,N185-,F186-,I210V,V213G,G257S,R346I,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.1 1254 15 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] B.1.349 1253 815 65.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.349 1253 103 8.2% 1 +[E554D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.349 1253 83 6.6% 1 +[T22N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.349 1253 24 1.9% 1 +[E156V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.349 1253 20 1.6% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.33 1252 885 70.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.33 1252 69 5.5% 1 +[H69-,V70-,K147I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.33 1252 44 3.5% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.33 1252 14 1.1% 2 +[H69-,V70-,K147I,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.33 1252 14 1.1% 6 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.31 1249 935 74.9% 0 +[H69-,V70-,L84I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.31 1249 73 5.8% 1 +[H69-,V70-,L84I,K182N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.31 1249 71 5.7% 1 +[H69-,V70-,L84I,W152L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.31 1249 10 0.8% 1 +[H69-,V70-,L84I,V213G,G339D,L452R,F486V,T778I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.31 1249 6 0.5% 1 +[L5F,H69-,V70-,L84I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.20 1249 1080 86.5% 0 +[N148T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.20 1249 44 3.5% 1 +[I68T,N148T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.20 1249 21 1.7% 1 +[N148T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.20 1249 8 0.6% 1 +[N148T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.20 1249 6 0.5% 1 +[N148T,V213G,G339D,Q493R,S929T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.70 1249 1010 80.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.70 1249 15 1.2% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.70 1249 15 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.70 1249 12 1.0% 1 +[T19L,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.70 1249 11 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.63 1244 847 68.1% 0 +[S12F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.63 1244 39 3.1% 1 +[S12F,N148T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.63 1244 24 1.9% 1 +[S12F,E654K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.63 1244 24 1.9% 2 +[S12F,N148T,L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.63 1244 21 1.7% 1 +[S12F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.64 1240 718 57.9% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.64 1240 272 21.9% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.64 1240 44 3.5% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,A701S,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.64 1240 15 1.2% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.64 1240 12 1.0% 2 +[L5F,T19R,H146L,E156G,F157-,R158-,A222V,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3 1239 705 56.9% 0 +[S12F,H69-,V70-,W152R,R346S,L452R,Q677H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.36.3 1239 61 4.9% 1 +[S12F,H69-,V70-,W152R,R346S,L452R,Q677H,A899S,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3 1239 20 1.6% 1 +[S12F,S13I,H69-,V70-,W152R,R346S,L452R,Q677H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3 1239 17 1.4% 1 +[S12F,H69-,V70-,W152R,R346S,L452R,T547I,Q677H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3 1239 15 1.2% 1 +[S12F,H69-,V70-,W152R,D253Y,R346S,L452R,Q677H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.10.1 1232 881 71.5% 0 +[E554K] (consensus) FL.10.1 1232 26 2.1% 1 +[H146K,E554K]-[H146Q] FL.10.1 1232 13 1.1% 1 +[E554K,F1075L] FL.10.1 1232 13 1.1% 1 +[E554K,D936Y] FL.10.1 1232 13 1.1% 1 +[E554K,A688V] BA.2.68 1227 1016 82.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.68 1227 25 2.0% 1 +[F157L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.68 1227 22 1.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.68 1227 17 1.4% 2 +[V213G,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.68 1227 9 0.7% 1 +[F157S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.157 1226 684 55.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.157 1226 160 13.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.157 1226 68 5.5% 2 +[S691P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.157 1226 63 5.1% 1 +[L585F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.157 1226 44 3.6% 1 +[V70A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.3 1222 733 60.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.3 1222 101 8.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.3 1222 65 5.3% 1 +[H69-,V70-,E180V,V213G,G339D,L452R,F486V,T547I,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.3 1222 34 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S,C1250F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.3 1222 27 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.1 1222 1053 86.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.5.1 1222 16 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.1 1222 16 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,K854R,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.1 1222 14 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.1 1222 14 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.47 1221 950 77.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.47 1221 31 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.47 1221 30 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.47 1221 20 1.6% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.47 1221 6 0.5% 2 +[H69-,V70-,V213G,G339D,L452R,V483A,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.6 1217 990 81.3% 0 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.6 1217 17 1.4% 1 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.6 1217 16 1.3% 1 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.6 1217 13 1.1% 1 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V,R1107S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.6 1217 12 1.0% 1 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.241 1212 571 47.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.241 1212 85 7.0% 1 +[V90F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.241 1212 62 5.1% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.241 1212 56 4.6% 3 +[V6I,D138Y,I197V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.241 1212 53 4.4% 2 +[Q677H,V1128I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.6.4 1211 944 78.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.6.4 1211 37 3.1% 1 +[H69-,V70-,V213G,G339D,V445F,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.4 1211 11 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.4 1211 11 0.9% 1 +[H69-,V70-,V213G,A264T,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.4 1211 11 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.147 1209 1062 87.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.147 1209 43 3.6% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.147 1209 23 1.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.147 1209 8 0.7% 1 +[W152R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.147 1209 6 0.5% 2 +[A694V,V1230L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.67 1209 567 46.9% 0 +[T19R,E156G,F157-,R158-,A222V,A262S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.67 1209 191 15.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.67 1209 110 9.1% 1 +[T19R,E156G,F157-,R158-,A222V,A262S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.67 1209 67 5.5% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.67 1209 41 3.4% 2 +[T19R,E156G,F157-,R158-,A222V,A348S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.3.11 1209 570 47.1% 0 +[D253G,T478R,P521S]-[G252V,T478K] (consensus) XBB.2.3.11 1209 77 6.4% 1 +[N185D,D253G,T478R,P521S]-[G252V,T478K] XBB.2.3.11 1209 43 3.6% 1 +[D253G,T478R,P521S,T883I]-[G252V,T478K] XBB.2.3.11 1209 41 3.4% 1 +[D253G,T478R,P521S,A845S]-[G252V,T478K] XBB.2.3.11 1209 20 1.7% 1 +[L216F,D253G,T478R,P521S]-[G252V,T478K] B.1.177.16 1201 1052 87.6% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.16 1201 17 1.4% 1 +[A27V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.16 1201 16 1.3% 1 +[A222V,S659L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.16 1201 12 1.0% 1 +[M153T,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.16 1201 9 0.7% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.77 1200 804 67.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.77 1200 223 18.6% 1 +[A222V,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.77 1200 26 2.2% 1 +[S98F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.77 1200 15 1.2% 1 +[A222V,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.77 1200 14 1.2% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.87 1196 634 53.0% 0 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.87 1196 172 14.4% 1 +[A222V,A262S,P272L,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.87 1196 102 8.5% 1 +[T19K,A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.87 1196 54 4.5% 1 +[L5F,A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.87 1196 44 3.7% 2 +[L176F,A222V,A262S,P272L,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.396 1195 861 72.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.396 1195 40 3.3% 1 +[Y612F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.396 1195 31 2.6% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.396 1195 16 1.3% 1 +[E1262D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.396 1195 14 1.2% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.35 1195 813 68.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.35 1195 48 4.0% 1 +[G72R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.35 1195 22 1.8% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.35 1195 19 1.6% 2 +[G769R,D1084G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.35 1195 19 1.6% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.6 1195 716 59.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.6 1195 163 13.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.6 1195 50 4.2% 1 +[H69-,V70-,G184V,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.6 1195 35 2.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,K1154R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.6 1195 28 2.3% 1 +[H69-,V70-,V213G,T307I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.36.1 1194 769 64.4% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.36.1 1194 165 13.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36.1 1194 37 3.1% 1 +[T19R,F92I,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36.1 1194 12 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36.1 1194 12 1.0% 2 +[T19R,F92I,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.16 1192 484 40.6% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.16 1192 292 24.5% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.16 1192 18 1.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.16 1192 18 1.5% 18 +[Q52H,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L455F,F456L,E554K,A570V,P621S,P681R,S939F,P1143L]-[H146Q,Q183E,V213E,G252V,R346T,L368I,P681H] JN.1.16 1192 17 1.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V407I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.1.15.2 1188 911 76.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,V320I,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.15.2 1188 29 2.4% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,V320I,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.2 1188 19 1.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,V320I,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.1.15.2 1188 17 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.2 1188 15 1.3% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,V320I,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S,N764K] B.1.564 1187 489 41.2% 0 +[E780Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.564 1187 356 30.0% 2 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564 1187 132 11.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564 1187 55 4.6% 1 +[A522S,E780Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564 1187 50 4.2% 1 +[E780Q,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2 1185 722 60.9% 0 +[D253G,F486S]-[G252V,F486P] (consensus) XBB.2 1185 19 1.6% 1 +[H146K,D253G,F486S]-[H146Q,G252V,F486P] XBB.2 1185 15 1.3% 1 +[D253G,F486S]-[Y144-,G252V,F486P] XBB.2 1185 11 0.9% 1 +[L5F,D253G,F486S]-[G252V,F486P] XBB.2 1185 11 0.9% 1 +[D253G,F486S]-[G252V,K417N,F486P] BA.2.14 1176 868 73.8% 0 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.14 1176 190 16.2% 4 +[W64L,V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.14 1176 20 1.7% 1 +[W64L,V213G,G339D,N450D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.14 1176 10 0.9% 1 +[W64L,V213G,G339D,Q493R,V534L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.14 1176 9 0.8% 1 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.6 1176 1073 91.2% 0 +[V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.6 1176 17 1.4% 1 +[V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.6 1176 6 0.5% 1 +[L5F,V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.6 1176 6 0.5% 1 +[F2L,V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.6 1176 5 0.4% 1 +[V213G,S255F,G339D,Q493R,P1263L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.46.2 1175 324 27.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.2 1175 200 17.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.2 1175 76 6.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,P809S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.2 1175 71 6.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,P809S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.2 1175 51 4.3% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.1.6 1175 1024 87.1% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.6 1175 20 1.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.6 1175 20 1.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,P1079S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.6 1175 15 1.3% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.1.6 1175 8 0.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,A958S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.4 1175 799 68.0% 0 +[T883I] (consensus) XBB.1.5.4 1175 22 1.9% 1 +[T883I]-[K417N] XBB.1.5.4 1175 18 1.5% 1 +[N164S,T883I] XBB.1.5.4 1175 18 1.5% 1 +[S704L,T883I] XBB.1.5.4 1175 15 1.3% 1 +[H146K,T883I]-[H146Q] XBB 1172 504 43.0% 0 +[F486S]-[G252V,F486P] (consensus) XBB 1172 21 1.8% 1 +[H146K,F486S]-[H146Q,G252V,F486P] XBB 1172 18 1.5% 1 +[F486S]-[G252V,K417N,F486P] XBB 1172 16 1.4% 1 +[F486S,E619Q]-[G252V,F486P] XBB 1172 16 1.4% 1 +[F486S]-[T19I,G252V,F486P] CK.1 1171 607 51.8% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1 1171 112 9.6% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1 1171 47 4.0% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] CK.1 1171 33 2.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1 1171 21 1.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,D1118V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FL.1.5.2 1171 779 66.5% 0 +[F456L,N481K,F490P,P681R,A701V]-[F490S,P681H] (consensus) FL.1.5.2 1171 90 7.7% 1 +[F456L,N481K,P681R,A701V]-[P681H] FL.1.5.2 1171 41 3.5% 1 +[F456L,N481K,F490P,P681R,A701V,V1228L]-[F490S,P681H] FL.1.5.2 1171 29 2.5% 3 +[V83T,K356T,F456L,N481K,F490P,T572I,P681R,A701V]-[V83A,F490S,P681H] FL.1.5.2 1171 19 1.6% 1 +[K304N,F456L,N481K,F490P,P681R,A701V]-[F490S,P681H] HK.3.1 1168 668 57.2% 0 +[Q52H,F157L,L455F,F456L] (consensus) HK.3.1 1168 83 7.1% 1 +[Q52H,H146K,F157L,L455F,F456L]-[H146Q] HK.3.1 1168 32 2.7% 1 +[Q52H,F157L,L455F,F456L,T478R]-[T478K] HK.3.1 1168 19 1.6% 1 +[Q52H,F157L,L455F,F456L,P681R]-[P681H] HK.3.1 1168 13 1.1% 1 +[Q52H,F157L,L455F,F456L]-[K417N] B.1.177.73 1166 653 56.0% 0 +[A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.73 1166 177 15.2% 1 +[L5F,A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.73 1166 72 6.2% 1 +[S98F,A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.73 1166 43 3.7% 1 +[T95I,A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.73 1166 13 1.1% 2 +[S98F,D215Y,A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.2 1163 617 53.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.34.2 1163 315 27.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.2 1163 21 1.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N,D1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.2 1163 16 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.2 1163 14 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.32 1163 876 75.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.32 1163 86 7.4% 1 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.32 1163 54 4.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.32 1163 14 1.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.32 1163 6 0.5% 2 +[V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.617 1160 403 34.7% 0 +[E154K,L452R,E484Q,P681R,Q1071H,H1101D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.617 1160 108 9.3% 3 +[E154K,V382L,L452R,E484Q,P681R,Q1071H,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617 1160 98 8.4% 1 +[E154K,Q218H,L452R,E484Q,P681R,Q1071H,H1101D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617 1160 50 4.3% 1 +[E154K,L452R,E484Q,P681R,Q1071H,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617 1160 49 4.2% 1 +[L452R,E484Q,P681R,Q1071H,H1101D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.139 1159 818 70.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.139 1159 80 6.9% 2 +[T941A,M1229L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.139 1159 37 3.2% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.139 1159 28 2.4% 1 +[G252D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.139 1159 22 1.9% 1 +[T618I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.31 1158 616 53.2% 0 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.31 1158 268 23.1% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.31 1158 26 2.2% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,V483I,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.31 1158 20 1.7% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V,I1232S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.31 1158 14 1.2% 2 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BE.1.2 1155 731 63.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.2 1155 57 4.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2 1155 28 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.2 1155 18 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2 1155 15 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D936N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.109 1154 431 37.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.109 1154 143 12.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.109 1154 139 12.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,H1058Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.109 1154 83 7.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.109 1154 66 5.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,S698L,D950N,H1058Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.12 1153 531 46.1% 0 +[T323I] (consensus) XBB.1.5.12 1153 174 15.1% 1 XBB.1.5.12 1153 30 2.6% 1 +[T323I]-[K417N] XBB.1.5.12 1153 17 1.5% 1 +[H146K,T323I]-[H146Q] XBB.1.5.12 1153 12 1.0% 3 -[R408S,S477N] AY.4.15 1153 942 81.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.15 1153 119 10.3% 1 +[V16F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.15 1153 35 3.0% 1 +[T19R,T95I,E156G,F157-,R158-,S161F,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.15 1153 5 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S,T1238A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.15 1153 5 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.50 1150 324 28.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.50 1150 87 7.6% 1 +[N481K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.50 1150 66 5.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.50 1150 58 5.0% 2 -[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.50 1150 47 4.1% 2 +[A67S,E96Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.10 1150 818 71.1% 0 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.10 1150 74 6.4% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.10 1150 22 1.9% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.10 1150 12 1.0% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V,E654K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.10 1150 11 1.0% 1 +[H69-,V70-,Y200C,V213G,A262S,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] HK.6 1147 729 63.6% 0 +[Q52H,D253G,F456L] (consensus) HK.6 1147 36 3.1% 1 +[Q52H,R78M,D253G,F456L] HK.6 1147 21 1.8% 1 +[Q52H,D253G,F456L,V1268I] HK.6 1147 15 1.3% 1 +[Q52H,D253G,F456L,Q675H] HK.6 1147 14 1.2% 1 +[Q52H,D253G,F456L,S704L] BA.4.7 1147 935 81.5% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.7 1147 19 1.7% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S,D1163N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.7 1147 17 1.5% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.7 1147 15 1.3% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.7 1147 15 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.46.1 1144 787 68.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.1 1144 82 7.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.1 1144 73 6.4% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.1 1144 25 2.2% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1127Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.1 1144 16 1.4% 1 +[T19R,P85L,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.2 1143 870 76.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.2 1143 40 3.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.2 1143 26 2.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.2 1143 18 1.6% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.2 1143 9 0.8% 1 +[H69-,V70-,V213G,T240I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.277 1139 508 44.6% 0 +[A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.277 1139 184 16.2% 1 +[A626S,E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.277 1139 123 10.8% 1 +[A626S,E1195Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.277 1139 97 8.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.277 1139 36 3.2% 1 +[H49Y,A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBC.1.3 1135 748 65.9% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.3 1135 51 4.5% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.3 1135 31 2.7% 1 +[P25S,E156G,F157-,R158-,Y170H,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.3 1135 21 1.9% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.3 1135 16 1.4% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,K444T,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] BA.5.2.8 1134 963 84.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.8 1134 18 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.8 1134 17 1.5% 1 +[H69-,V70-,E180G,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.8 1134 15 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.8 1134 7 0.6% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.26 1133 992 87.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.26 1133 34 3.0% 1 +[V213G,G339D,Q493R,G1267R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.26 1133 9 0.8% 1 +[V213G,G339D,Q493R,C1236F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.26 1133 9 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.26 1133 7 0.6% 1 +[V213G,G339D,V483A,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.348 1130 455 40.3% 0 +[G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.348 1130 133 11.8% 1 +[A879S,G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.348 1130 73 6.5% 2 +[R346K,G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.348 1130 68 6.0% 1 +[V289I,G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.348 1130 51 4.5% 1 +[A348S,G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.3 1129 870 77.1% 0 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.221.3 1129 70 6.2% 1 +[H49Y,S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.3 1129 64 5.7% 1 +[S98F,V1065L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.3 1129 51 4.5% 1 +[S98F,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.3 1129 24 2.1% 1 +[S98F,S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.18 1124 740 65.8% 0 (consensus) XBB.1.5.18 1124 48 4.3% 2 +[W152R,T478R]-[T478K] XBB.1.5.18 1124 19 1.7% 2 +[F456L,Q675K] XBB.1.5.18 1124 16 1.4% 1 +[H146K]-[H146Q] XBB.1.5.18 1124 15 1.3% 4 +[W152R,T478R,E554Q,D1184Y]-[T478K] BQ.1.15 1120 858 76.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.15 1120 43 3.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.15 1120 36 3.2% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S1252Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.15 1120 18 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.15 1120 12 1.1% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q675K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DV.1.1 1118 822 73.5% 0 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.1.1 1118 31 2.8% 1 +[K147E,W152R,F157L,L176F,L179P,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.1.1 1118 22 2.0% 1 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.1.1 1118 17 1.5% 2 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,A344T,K444T,L452R,F486S,A522S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.1.1 1118 14 1.3% 1 +[N30S,K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.11 1100 757 68.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.11 1100 39 3.5% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.11 1100 23 2.1% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T883I,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.11 1100 15 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,P322A,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.11 1100 10 0.9% 2 +[K147E,W152R,F157L,I210V,L212S,V213G,G257S,R408N,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] B.1.1.416 1098 794 72.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.416 1098 24 2.2% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.416 1098 21 1.9% 1 +[P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.416 1098 14 1.3% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.416 1098 13 1.2% 2 +[E156D,T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BL.1 1097 702 64.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BL.1 1097 24 2.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,S680F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.1 1097 22 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] BL.1 1097 18 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BL.1 1097 14 1.3% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BF.7.23 1095 893 81.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.23 1095 31 2.8% 1 +[V3I,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.23 1095 23 2.1% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.23 1095 19 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.23 1095 10 0.9% 2 +[H69-,V70-,V213G,T323I,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.409 1091 881 80.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.409 1091 27 2.5% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.409 1091 13 1.2% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.409 1091 12 1.1% 1 +[H1088R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.409 1091 10 0.9% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.56 1085 816 75.2% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.56 1085 84 7.7% 1 +[A222V,P809L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.56 1085 25 2.3% 1 +[D138H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.56 1085 22 2.0% 1 +[A222V,S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.56 1085 16 1.5% 1 +[I119V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.52 1084 553 51.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.52 1084 228 21.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.52 1084 61 5.6% 2 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.52 1084 15 1.4% 1 +[H69-,V70-,V213G,G339D,K417T,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.52 1084 15 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.426 1081 841 77.8% 0 +[D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.426 1081 38 3.5% 1 +[D253G,T719I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.426 1081 26 2.4% 2 +[D253G,A263T,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.426 1081 24 2.2% 1 +[H49Y,D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.426 1081 19 1.8% 1 +[L5F,D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.77 1081 591 54.7% 0 (consensus) XBB.1.5.77 1081 39 3.6% 1 +[H146K]-[H146Q] XBB.1.5.77 1081 15 1.4% 2 +[L84I,T588I] XBB.1.5.77 1081 13 1.2% 1 -[R408S] XBB.1.5.77 1081 13 1.2% 1 -[K417N] HH.1 1081 800 74.0% 0 +[G184V,D253G,P521S]-[G252V] (consensus) HH.1 1081 28 2.6% 1 +[H146K,G184V,D253G,P521S]-[H146Q,G252V] HH.1 1081 17 1.6% 1 +[G184V,D253G,Q493L,P521S]-[G252V] HH.1 1081 11 1.0% 1 +[G184V,D253G,P521S]-[G252V,K417N] HH.1 1081 8 0.7% 2 +[G184V,D253G,G257S,E340Q,P521S]-[G252V] B.1.329 1079 1051 97.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.329 1079 3 0.3% 1 +[A163V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.329 1079 3 0.3% 1 +[N17D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.329 1079 2 0.2% 1 +[H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.329 1079 2 0.2% 1 +[A623V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.35 1078 456 42.3% 0 +[N978S] (consensus) XBB.1.5.35 1078 174 16.1% 1 +[S98F,N978S] XBB.1.5.35 1078 72 6.7% 1 +[D198G,N978S] XBB.1.5.35 1078 50 4.6% 1 +[N978S]-[K417N] XBB.1.5.35 1078 18 1.7% 1 +[H146K,N978S]-[H146Q] BA.5.2.44 1075 617 57.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.44 1075 101 9.4% 2 +[H69-,V70-,N185D,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.44 1075 46 4.3% 3 +[H69-,V70-,N185D,V213G,G339D,L452R,F486V,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.44 1075 37 3.4% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.44 1075 32 3.0% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.99.1 1075 443 41.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.99.1 1075 226 21.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.1 1075 42 3.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.1 1075 29 2.7% 2 +[T19R,E156G,F157-,R158-,D427G,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.1 1075 19 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17.1 1073 1011 94.2% 0 +[L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.17.1 1073 12 1.1% 1 +[L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17.1 1073 6 0.6% 1 +[L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,A879S,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17.1 1073 5 0.5% 1 +[V3A,L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17.1 1073 5 0.5% 1 +[L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,T523N,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.509 1072 869 81.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.509 1072 24 2.2% 2 +[D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.509 1072 14 1.3% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.509 1072 11 1.0% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.509 1072 10 0.9% 1 +[T76I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.24 1064 711 66.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.24 1064 58 5.5% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.24 1064 48 4.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,L1197F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.24 1064 16 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.24 1064 14 1.3% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] FY.5 1063 255 24.0% 0 +[Y200C,T478R]-[T478K] FY.5 1063 226 21.3% 1 +[Y200C,T478R,T572I]-[T478K] (consensus) FY.5 1063 202 19.0% 4 +[M153I,F186S,Y200C,S247N,T478R,T572I]-[T478K] FY.5 1063 24 2.3% 1 +[L176F,Y200C,T478R]-[T478K] FY.5 1063 22 2.1% 1 +[Y200C,A222V,T478R]-[T478K] CQ.2 1062 923 86.9% 0 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CQ.2 1062 18 1.7% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CQ.2 1062 15 1.4% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] CQ.2 1062 10 0.9% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] CQ.2 1062 7 0.7% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486V,S940F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.10 1053 916 87.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.10 1053 18 1.7% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.10 1053 10 0.9% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.10 1053 9 0.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,S691P,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.10 1053 8 0.8% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,M177I,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,D1163G]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.177.15 1053 831 78.9% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.15 1053 38 3.6% 1 +[S12F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.15 1053 34 3.2% 1 +[A222V,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.15 1053 23 2.2% 1 +[A222V,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.15 1053 21 2.0% 1 +[A222V,G1167F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.2 1052 597 56.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.2 1052 178 16.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.2 1052 106 10.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.2 1052 16 1.5% 1 +[T19R,E156G,F157-,R158-,L452R,E471Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.2 1052 8 0.8% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EU.1.1 1050 790 75.2% 0 +[I410V,P521S] (consensus) EU.1.1 1050 20 1.9% 1 +[I410V,S494P,P521S] EU.1.1 1050 18 1.7% 1 +[I410V,P521S]-[K417N] EU.1.1 1050 17 1.6% 1 +[H146K,I410V,P521S]-[H146Q] EU.1.1 1050 15 1.4% 1 +[Q14K,I410V,P521S] GF.1 1048 774 73.9% 0 +[E748V] (consensus) GF.1 1048 30 2.9% 1 +[H146K,E748V]-[H146Q] GF.1 1048 29 2.8% 1 +[R408G,E748V]-[R408S] GF.1 1048 10 1.0% 1 +[E748V]-[K417N] GF.1 1048 8 0.8% 2 +[E748V]-[R408S,S477N] AZ.2 1048 827 78.9% 0 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AZ.2 1048 36 3.4% 1 +[T95I,G252S,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.2 1048 19 1.8% 2 +[T95I,E484K,Q607K,D796H,S875A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.2 1048 19 1.8% 1 +[L5F,T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.2 1048 10 1.0% 2 +[T95I,G252S,E484K,S640F,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BQ.1.2.1 1048 795 75.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.2.1 1048 73 7.0% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2.1 1048 17 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V,D1139H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2.1 1048 11 1.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.2.1 1048 7 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] XBB.1.5.11 1047 669 63.9% 0 (consensus) XBB.1.5.11 1047 35 3.3% 1 +[H146K]-[H146Q] XBB.1.5.11 1047 20 1.9% 1 +[S704L] XBB.1.5.11 1047 19 1.8% 1 +[T883I] XBB.1.5.11 1047 13 1.2% 1 -[K417N] XBC.1.6 1045 710 67.9% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.6 1045 100 9.6% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,V445A,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6 1045 50 4.8% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,A899S]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6 1045 16 1.5% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,K811R]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6 1045 15 1.4% 1 +[P25S,E156G,F157-,R158-,G184V,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] B.1.1.372 1041 705 67.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.372 1041 192 18.4% 1 +[P26L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.372 1041 9 0.9% 2 +[P26L,T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.372 1041 7 0.7% 2 +[P26L,L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.372 1041 7 0.7% 1 +[T323I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.32 1040 578 55.6% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.32 1040 138 13.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.32 1040 35 3.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,N657D,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.32 1040 19 1.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.32 1040 10 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] FL.24 1040 416 40.0% 0 +[T478R,Q613H,A688V]-[T478K] (consensus) FL.24 1040 259 24.9% 1 +[Q613H,A688V] FL.24 1040 32 3.1% 2 +[T478R,E554K,Q613H,A688V,T961M]-[T478K] FL.24 1040 13 1.2% 2 +[I105V,T478R,Q613H,T678I,A688V]-[T478K] FL.24 1040 13 1.2% 1 +[T478R,Q613H,A688V,V1264L]-[T478K] XBB.1.5.51 1038 716 69.0% 0 (consensus) XBB.1.5.51 1038 73 7.0% 1 +[T478R]-[T478K] XBB.1.5.51 1038 23 2.2% 1 +[T29I] XBB.1.5.51 1038 21 2.0% 1 +[H146K]-[H146Q] XBB.1.5.51 1038 12 1.2% 1 -[K417N] XBB.1.22.1 1033 342 33.1% 0 +[Y200C,T572I] (consensus) XBB.1.22.1 1033 220 21.3% 1 +[Y200C] XBB.1.22.1 1033 43 4.2% 1 +[A67S,Y200C,T572I] XBB.1.22.1 1033 27 2.6% 2 XBB.1.22.1 1033 23 2.2% 2 +[Y200C,Q675K] B.1.177.8 1030 807 78.3% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.8 1030 135 13.1% 1 +[L18F,A222V,I794L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.8 1030 5 0.5% 1 +[L18F,A222V,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.8 1030 5 0.5% 2 +[L18F,A222V,I794L,G1085R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.8 1030 4 0.4% 1 +[L18F,A222V,S373L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.42 1028 874 85.0% 0 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.42 1028 28 2.7% 1 +[I68T,R78G,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.42 1028 17 1.7% 1 +[I68T,V213G,G339D,Q493R,M1229I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.42 1028 12 1.2% 1 +[I68T,V213G,G339D,Q493R,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.42 1028 7 0.7% 1 +[I68T,V213G,G339D,Q493R,T778A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.19.1 1026 889 86.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.19.1 1026 25 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.19.1 1026 18 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1104L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.19.1 1026 10 1.0% 1 +[H69-,V70-,V213G,L244S,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.19.1 1026 7 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S813I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] P.1.4 1024 870 85.0% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.4 1024 24 2.3% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,R646H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.4 1024 9 0.9% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,V622F,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.4 1024 9 0.9% 1 +[L18F,T20N,P26S,D138Y,R190S,G257D,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.4 1024 8 0.8% 2 +[L18F,T20N,P26S,D138Y,R190S,A243-,L244-,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] BA.2.49 1023 491 48.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.49 1023 322 31.5% 1 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.49 1023 47 4.6% 1 +[V213G,G339D,Q493R,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.49 1023 22 2.2% 2 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.49 1023 17 1.7% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.50 1021 934 91.5% 0 +[T19R,E156G,F157-,R158-,V308L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.50 1021 20 2.0% 1 +[T19R,E156G,F157-,R158-,V308L,L452R,P681R,D950N,V1228I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.50 1021 17 1.7% 1 +[T19R,E156G,F157-,R158-,V308L,L452R,P681R,D950N,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.50 1021 9 0.9% 1 +[T19R,E156G,F157-,R158-,V308L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.50 1021 3 0.3% 1 +[T19R,E156G,F157-,R158-,V308L,L452R,P681R,D950N,E1144V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102 1017 496 48.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.102 1017 107 10.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102 1017 54 5.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102 1017 33 3.2% 1 +[T19R,T95I,E156G,F157-,R158-,M177I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102 1017 27 2.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D936Y,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.15 1016 672 66.1% 0 +[V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.15 1016 113 11.1% 1 +[V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.15 1016 45 4.4% 1 +[V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.3.15 1016 24 2.4% 2 +[V213G,D215E,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.15 1016 20 2.0% 1 +[F157S,V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.22 1015 791 77.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.22 1015 20 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.22 1015 11 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,I1183V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.22 1015 10 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.22 1015 9 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BA.2.3.12 1009 836 82.9% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.12 1009 14 1.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.12 1009 11 1.1% 2 +[V213G,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.3.12 1009 10 1.0% 1 +[V213G,T286I,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.12 1009 9 0.9% 1 +[V213G,G339D,Q493R,I1225V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.588 1008 747 74.1% 0 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.588 1008 28 2.8% 1 +[T20I,A626V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.588 1008 27 2.7% 1 +[T20I,I68L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.588 1008 24 2.4% 1 +[T20I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.588 1008 15 1.5% 1 +[T20I,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.17 1006 581 57.8% 0 +[L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.17 1006 213 21.2% 1 +[L5F,L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.17 1006 59 5.9% 2 +[A222V,A846S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.17 1006 33 3.3% 2 +[L176F,A222V,A1078S,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.17 1006 23 2.3% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.65 1005 770 76.6% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.65 1005 169 16.8% 1 +[L18F,G181V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.65 1005 19 1.9% 2 +[L18F,G75S,G181V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.65 1005 12 1.2% 1 +[L5F,L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.65 1005 4 0.4% 1 +[L18F,A222V,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.6.2 1004 778 77.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.6.2 1004 30 3.0% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.6.2 1004 15 1.5% 2 +[H69-,V70-,N211-,L212I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.2 1004 11 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.2 1004 10 1.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.73 1002 256 25.5% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.73 1002 247 24.7% 1 +[T19R,W152L,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.73 1002 178 17.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.73 1002 99 9.9% 1 +[T19R,E156G,F157-,R158-,I210V,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.73 1002 15 1.5% 2 +[T19R,E156G,F157-,R158-,I210V,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.21 999 646 64.7% 0 (consensus) XBB.1.5.21 999 27 2.7% 1 +[H146K]-[H146Q] XBB.1.5.21 999 23 2.3% 2 -[R408S,S477N] XBB.1.5.21 999 20 2.0% 1 -[N764K] XBB.1.5.21 999 16 1.6% 1 +[A260S] BQ.1.3 997 671 67.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.3 997 51 5.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,V1133A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3 997 44 4.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3 997 14 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,T1120I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3 997 12 1.2% 1 +[H69-,V70-,W152R,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.2.13.1 994 771 77.6% 0 +[V213G,G339D,L452M,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.13.1 994 57 5.7% 1 +[V213G,G339D,L452M,Q493R,A892V,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13.1 994 28 2.8% 1 +[V213G,P217S,G339D,L452M,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13.1 994 23 2.3% 1 +[V213G,G339D,L452M,Q493R,P812L,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13.1 994 9 0.9% 1 +[L5F,V213G,G339D,L452M,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.3 991 754 76.1% 0 (consensus) FL.3 991 32 3.2% 1 +[H1159R] FL.3 991 12 1.2% 1 -[K417N] FL.3 991 11 1.1% 1 +[H146K]-[H146Q] FL.3 991 8 0.8% 1 +[L5F] B.1.422 988 871 88.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.422 988 27 2.7% 1 +[G184S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.422 988 17 1.7% 1 +[P384R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.422 988 10 1.0% 1 +[T1009S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.422 988 7 0.7% 1 +[G257S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.67 986 696 70.6% 0 (consensus) XBB.1.5.67 986 23 2.3% 1 +[H146K]-[H146Q] XBB.1.5.67 986 15 1.5% 1 +[G257S] XBB.1.5.67 986 14 1.4% 1 +[T573I] XBB.1.5.67 986 13 1.3% 1 +[V62L] BA.5.2.49 986 769 78.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.49 986 13 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I,D1146Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.49 986 12 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.49 986 10 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.49 986 8 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.52 980 645 65.8% 0 +[V213G,Y248S,+248GEN,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.52 980 137 14.0% 4 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.52 980 48 4.9% 1 +[V213G,Y248S,+248GEN,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.52 980 8 0.8% 1 +[V213G,Y248S,+248GEN,G339D,Q493R,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.52 980 8 0.8% 5 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] P.1.2 980 598 61.0% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.2 980 61 6.2% 1 +[L18F,T20N,P26S,D138Y,R190S,A262S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.2 980 31 3.2% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.2 980 19 1.9% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.2 980 17 1.7% 2 +[L18F,T20N,P26S,D138Y,R190S,A262S,K417T,E484K,Q675H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] FE.1.2 977 415 42.5% 0 +[F456L] (consensus) FE.1.2 977 112 11.5% 1 +[F456L]-[R346T] FE.1.2 977 61 6.2% 2 +[F456L]-[R346T,K417N] FE.1.2 977 29 3.0% 1 +[H146K,F456L]-[H146Q] FE.1.2 977 16 1.6% 1 +[F456L]-[K417N] BA.2.41 976 570 58.4% 0 +[+212T,+213GGG,G339D,Q493R,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.41 976 186 19.1% 5 +[V213G,G339D,Q493R,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.41 976 96 9.8% 6 +[V213G,G339D,Q493R,A942S,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.41 976 11 1.1% 1 +[+212T,+213GGG,G339D,Q493R,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.41 976 10 1.0% 1 +[+212T,+213GGG,G339D,Q493R,A688V,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.367 970 715 73.7% 0 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.367 970 100 10.3% 1 +[D80Y,V90F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.367 970 33 3.4% 1 +[D80Y,D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.367 970 9 0.9% 1 +[L5F,D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.367 970 6 0.6% 1 +[D80Y,I794V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.59 969 547 56.4% 0 +[F456L] (consensus) XBB.1.5.59 969 72 7.4% 1 +[H146K,F456L]-[H146Q] XBB.1.5.59 969 24 2.5% 1 +[M177I,F456L] XBB.1.5.59 969 23 2.4% 1 +[F456L,V510I] XBB.1.5.59 969 14 1.4% 1 +[F456L]-[K417N] GN.1 967 549 56.8% 0 +[F456L] (consensus) GN.1 967 60 6.2% 1 +[G181V,F456L] GN.1 967 47 4.9% 1 +[F456L,T747I] GN.1 967 39 4.0% 1 +[H146K,F456L]-[H146Q] GN.1 967 16 1.7% 1 +[F456L]-[R408S] AY.122.3 967 908 93.9% 0 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.3 967 8 0.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.3 967 7 0.7% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.3 967 3 0.3% 1 +[T19R,N30H,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.3 967 3 0.3% 1 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,A684V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.48 964 365 37.9% 0 +[T19R,K77T,E156G,F157-,R158-,L452R,T547I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.48 964 151 15.7% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.48 964 102 10.6% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,T547I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.48 964 83 8.6% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,T547I,V622A,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.48 964 49 5.1% 2 +[T19R,K77T,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.75 961 224 23.3% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.75 961 168 17.5% 1 +[A222V,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.75 961 159 16.5% 1 +[A222V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.75 961 107 11.1% 1 +[Y144F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.75 961 32 3.3% 1 +[A222V,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.216 957 524 54.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.216 957 23 2.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.216 957 17 1.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.216 957 16 1.7% 1 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.216 957 15 1.6% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.9 957 258 27.0% 0 +[F486S]-[F486P] XBB.1.9 957 180 18.8% 1 (consensus) XBB.1.9 957 29 3.0% 1 +[F486S,S813G]-[F486P] XBB.1.9 957 29 3.0% 2 +[Q613H] XBB.1.9 957 24 2.5% 2 +[F456L] CM.2 957 752 78.6% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.2 957 13 1.4% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478E,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] CM.2 957 11 1.1% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N448D,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.2 957 10 1.0% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.2 957 7 0.7% 1 +[M153T,N164K,V213G,H245N,G257D,A263T,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BN.1.2.5 952 685 72.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.5 952 59 6.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A520S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.5 952 20 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F565I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.5 952 15 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.5 952 10 1.1% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBB.1.5.95 948 547 57.7% 0 (consensus) XBB.1.5.95 948 35 3.7% 1 +[E725D] XBB.1.5.95 948 29 3.1% 1 -[K417N] XBB.1.5.95 948 20 2.1% 1 +[T51I] XBB.1.5.95 948 15 1.6% 1 +[L1265F] CJ.1.3 947 731 77.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) CJ.1.3 947 18 1.9% 1 +[R21T,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3 947 12 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3 947 10 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3 947 9 1.0% 1 +[K147E,W152R,F157L,D178H,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBB.1.5.73 946 633 66.9% 0 (consensus) XBB.1.5.73 946 35 3.7% 1 +[F456L] XBB.1.5.73 946 19 2.0% 1 +[N1187S] XBB.1.5.73 946 11 1.2% 1 -[Q183E] XBB.1.5.73 946 10 1.1% 2 +[S514F,V687L] B.1.1.420 944 335 35.5% 0 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.420 944 175 18.5% 1 +[L18F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.420 944 72 7.6% 2 +[L18F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.420 944 47 5.0% 2 +[L18F,P26S,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.420 944 46 4.9% 1 +[L18F,H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.21 939 658 70.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.21 939 27 2.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.21 939 19 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.21 939 16 1.7% 1 +[H69-,V70-,K182R,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.21 939 13 1.4% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.35 937 510 54.4% 0 +[T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.35 937 106 11.3% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.35 937 78 8.3% 1 +[L5F,T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.35 937 62 6.6% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D808E,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.35 937 40 4.3% 2 +[L5F,T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.316 936 352 37.6% 0 +[Q677H,T732S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.316 936 300 32.1% 1 +[Q677H,T732S,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.316 936 48 5.1% 2 +[V213L,Q677H,T732S,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.316 936 28 3.0% 1 +[S94F,Q677H,T732S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.316 936 28 3.0% 1 +[T76I,Q677H,T732S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.1 935 760 81.3% 0 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.1 935 60 6.4% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.1 935 35 3.7% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N,I1221V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.1 935 6 0.6% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N,N969S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.1 935 5 0.5% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.52 935 615 65.8% 0 (consensus) XBB.1.5.52 935 32 3.4% 1 +[F456L] XBB.1.5.52 935 24 2.6% 2 +[L176F,T236S] XBB.1.5.52 935 18 1.9% 1 +[T236S] XBB.1.5.52 935 13 1.4% 1 +[H146K]-[H146Q] BA.5.6.1 930 416 44.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.6.1 930 261 28.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.1 930 34 3.7% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.6.1 930 19 2.0% 2 +[H69-,V70-,K147I,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.6.1 930 18 1.9% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.43.3 929 507 54.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.3 929 170 18.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.3 929 42 4.5% 1 +[T19R,E156G,F157-,R158-,V367L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.3 929 25 2.7% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.3 929 14 1.5% 2 +[T19R,E156G,F157-,R158-,V367L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BG.2 929 846 91.1% 0 +[V213G,G339D,L452Q,Q493R,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BG.2 929 9 1.0% 1 +[V213G,G339D,L452Q,Q493R,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BG.2 929 7 0.8% 1 +[V213G,G339D,L452Q,Q493R,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BG.2 929 6 0.6% 1 +[L5F,V213G,G339D,L452Q,Q493R,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.2 929 5 0.5% 1 +[V213G,G339D,L452Q,Q493R,A522P,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FE.1.1 928 645 69.5% 0 +[F456L] (consensus) FE.1.1 928 29 3.1% 1 +[H146K,F456L]-[H146Q] FE.1.1 928 10 1.1% 1 +[F456L,V1228A] FE.1.1 928 9 1.0% 1 +[F456L]-[R346T] FE.1.1 928 8 0.9% 1 +[F456L,T1117I] FY.2 928 641 69.1% 0 +[I197T,Y200C] (consensus) FY.2 928 39 4.2% 1 +[I197T,Y200C,V1264L] FY.2 928 24 2.6% 1 +[I197T,Y200C,I210-] FY.2 928 18 1.9% 1 +[H146K,I197T,Y200C]-[H146Q] FY.2 928 14 1.5% 1 +[Q173K,I197T,Y200C] BA.2.47 913 718 78.6% 0 +[V213G,Y248H,G339D,Q493R,S1261Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.47 913 68 7.4% 2 +[V213G,Y248H,G339D,Q493R,A1020S,P1143S,S1261Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.47 913 57 6.2% 4 +[V213G,Y248H,G339D,Q493R,S1261Y]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.47 913 16 1.8% 1 +[V213G,Y248H,G339D,Q493R,S1261Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.47 913 6 0.7% 1 +[V213G,Y248H,G339D,Q493R,S1261Y]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.9 909 629 69.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.9 909 57 6.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.9 909 16 1.8% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.9 909 12 1.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1244F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.9 909 10 1.1% 3 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] AY.122.4 906 483 53.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.4 906 213 23.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.4 906 16 1.8% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.4 906 12 1.3% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.4 906 10 1.1% 3 +[T19R,H49Y,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.6 905 579 64.0% 0 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.6 905 155 17.1% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.6 905 15 1.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.6 905 11 1.2% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,E780D,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.6 905 10 1.1% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N,D1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2.1 904 601 66.5% 0 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.120.2.1 904 130 14.4% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2.1 904 83 9.2% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1050I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2.1 904 12 1.3% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,A522S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2.1 904 10 1.1% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,S810A,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.24 904 638 70.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.24 904 78 8.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.24 904 61 6.7% 2 +[H69-,V70-,N185I,F186-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.24 904 6 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T1117I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.24 904 6 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,P479L,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.320 900 532 59.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.320 900 145 16.1% 1 +[V6F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.320 900 74 8.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.320 900 49 5.4% 1 +[S221L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.320 900 12 1.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.72 900 448 49.8% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.72 900 187 20.8% 1 +[T19R,E156G,F157-,R158-,F201L,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.72 900 79 8.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.72 900 12 1.3% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.72 900 9 1.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.5.2 900 602 66.9% 0 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.5.2 900 101 11.2% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.2 900 17 1.9% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,P561S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.2 900 15 1.7% 1 +[H69-,V70-,T76I,V90L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.2 900 11 1.2% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.126 899 689 76.6% 0 +[D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.126 899 37 4.1% 1 +[D215Y,A1078V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.126 899 31 3.4% 1 +[R78M,D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.126 899 29 3.2% 1 +[D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.126 899 13 1.4% 1 +[D215Y,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FK.1.1 898 666 74.2% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.1 898 24 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,M1237I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1 898 22 2.4% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1 898 15 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,K558R,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1 898 14 1.6% 1 +[K147E,W152L,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FU.2.1 896 736 82.1% 0 +[E180V,T478R,T547I,E619Q]-[T478K] (consensus) FU.2.1 896 11 1.2% 1 +[E180V,Y351F,T478R,T547I,E619Q]-[T478K] FU.2.1 896 9 1.0% 1 +[H146K,E180V,T478R,T547I,E619Q]-[H146Q,T478K] FU.2.1 896 7 0.8% 1 +[E180V,T478R,T547I,E619Q]-[R408S,T478K] FU.2.1 896 5 0.6% 1 +[E180V,T478R,T547I,E619Q]-[K417N,T478K] JN.1.18 896 475 53.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.18 896 89 9.9% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.18 896 31 3.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.18 896 20 2.2% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.18 896 8 0.9% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] AY.123 891 472 53.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.123 891 118 13.2% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.123 891 70 7.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.123 891 35 3.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,Q1201H,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.123 891 19 2.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162S,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.389 891 772 86.6% 0 +[T723I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.389 891 16 1.8% 1 +[T723I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.389 891 14 1.6% 1 +[T723I,E1202D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.389 891 9 1.0% 1 +[W258L,T723I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.389 891 5 0.6% 1 +[I472V,T723I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.10 890 658 73.9% 0 +[A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.10 890 48 5.4% 1 +[A222V,A262S,P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.10 890 21 2.4% 2 +[Q52R,A222V,A262S,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.10 890 16 1.8% 1 +[A222V,A262S,H1083Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.10 890 11 1.2% 2 +[A222V,S254P,A262S,P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.63 889 604 67.9% 0 (consensus) XBB.1.5.63 889 35 3.9% 1 +[K1205R] XBB.1.5.63 889 20 2.2% 1 -[T19I] XBB.1.5.63 889 15 1.7% 1 +[T299I] XBB.1.5.63 889 15 1.7% 1 +[H146K]-[H146Q] BA.2.3.14 889 713 80.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.14 889 16 1.8% 2 +[V213G,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.3.14 889 15 1.7% 1 +[V213G,G339D,Q493R,T1273I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.14 889 11 1.2% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.14 889 9 1.0% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] CK.2.1 887 406 45.8% 0 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.2.1 887 226 25.5% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1 887 24 2.7% 1 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1 887 16 1.8% 1 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] CK.2.1 887 14 1.6% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.25 887 633 71.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.25 887 65 7.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.25 887 21 2.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.25 887 15 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.25 887 14 1.6% 1 +[H69-,V70-,V213G,G339D,T430I,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.25 887 732 82.5% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.25 887 19 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.25 887 7 0.8% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.25 887 7 0.8% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,G1085R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.25 887 6 0.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,T478E,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BA.5.7 885 767 86.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.7 885 9 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.7 885 7 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.7 885 6 0.7% 2 +[V6I,H69-,V70-,V213G,G339D,L452R,Y453F,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.7 885 4 0.5% 1 +[H69-,V70-,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.33 883 689 78.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.33 883 30 3.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.33 883 13 1.5% 1 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.33 883 12 1.4% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.33 883 11 1.2% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XBB.1.16.9 883 577 65.3% 0 +[E180V,F456L,T478R]-[T478K] (consensus) XBB.1.16.9 883 57 6.5% 1 +[E180V,F456L,T478R,S494P]-[T478K] XBB.1.16.9 883 26 2.9% 1 +[E180V,S256L,F456L,T478R]-[T478K] XBB.1.16.9 883 23 2.6% 1 +[E180V,A344S,F456L,T478R]-[T478K] XBB.1.16.9 883 17 1.9% 1 +[E180V,F456L,T478R,K529N]-[T478K] BA.5.1.4 881 736 83.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.4 881 11 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.4 881 9 1.0% 1 +[H69-,V70-,L212S,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.4 881 9 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.4 881 8 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.51 879 208 23.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.51 879 182 20.7% 2 +[T19R,E156G,F157-,R158-,L452R,A520S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.51 879 171 19.5% 1 +[T19R,E156G,F157-,R158-,L452R,A520S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.51 879 95 10.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.51 879 16 1.8% 3 +[T19R,E156G,F157-,R158-,L452R,A520S,P681R,D950N,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BW.1.1 878 695 79.2% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BW.1.1 878 22 2.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BW.1.1 878 9 1.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,P621S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1.1 878 8 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1.1 878 6 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,V635I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.6 877 558 63.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.6 877 68 7.8% 1 +[H69-,V70-,V213G,D215H,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.6 877 36 4.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I1130M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.6 877 32 3.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q1142R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.6 877 20 2.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,F855L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] AY.16 877 341 38.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.16 877 128 14.6% 2 +[T19R,E156G,F157-,R158-,D215H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.16 877 99 11.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.16 877 33 3.8% 1 +[T19R,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.16 877 27 3.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.3.1 876 580 66.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] (consensus) BN.3.1 876 40 4.6% 2 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S,K356T,N450D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.3.1 876 17 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,F486P] BN.3.1 876 13 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D,N1187T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.3.1 876 13 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] AY.3.3 870 590 67.8% 0 +[T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.3.3 870 91 10.5% 1 +[T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.3 870 46 5.3% 1 +[T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.3 870 24 2.8% 1 +[L5F,T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.3 870 8 0.9% 2 +[T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.12 868 467 53.8% 0 +[L18F,T20N,P26S,D138Y,R190S,R246G,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.12 868 246 28.3% 2 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.12 868 27 3.1% 1 +[L18F,T20N,P26S,D138Y,R190S,R246G,K417T,E484K,T961M,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.12 868 11 1.3% 3 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,N536S,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.12 868 7 0.8% 4 +[L5F,L18F,T20N,P26S,D138Y,K150R,R190S,R246G,K417T,E484K,T547I,G769K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] HK.1 866 160 18.5% 0 +[Q52H,G257V,F456L] HK.1 866 151 17.4% 2 +[Q52H,G257V,T307I,L455F,F456L] HK.1 866 126 14.5% 2 +[Q52H,L455F,F456L] HK.1 866 60 6.9% 1 +[Q52H,G257V,L455F,F456L] (consensus) HK.1 866 40 4.6% 1 +[Q52H,G257V,F456L,P1263L] XBB.1.5.2 862 579 67.2% 0 +[K147I,T284I] (consensus) XBB.1.5.2 862 62 7.2% 1 +[T284I] XBB.1.5.2 862 24 2.8% 1 +[K147I,V213D,T284I]-[V213E] XBB.1.5.2 862 14 1.6% 1 +[K147I,T284I,K558N] XBB.1.5.2 862 13 1.5% 1 +[K147I,T284I,S494P] B.1.1.207 859 405 47.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.207 859 282 32.8% 1 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.207 859 12 1.4% 2 +[P85S,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.207 859 8 0.9% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.207 859 7 0.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] EG.5.2 854 411 48.1% 0 +[F456L] (consensus) EG.5.2 854 108 12.6% 2 +[H69-,V70-,F456L] EG.5.2 854 41 4.8% 1 +[F456L,A845S] EG.5.2 854 26 3.0% 2 +[H146K,F456L,A845S]-[H146Q] EG.5.2 854 17 2.0% 1 +[H146K,F456L]-[H146Q] BY.1 853 512 60.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BY.1 853 19 2.2% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1 853 17 2.0% 1 +[K147E,W152R,F157L,I210V,N211T,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1 853 14 1.6% 2 +[K147E,W152R,F157L,I210V,N211T,V213G,G257S,F486S,A522S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1 853 14 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452Q,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BQ.1.1.35 853 645 75.6% 0 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.35 853 33 3.9% 1 +[L5F,H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.35 853 13 1.5% 2 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V,T547K,V687I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.35 853 13 1.5% 1 +[H69-,V70-,K147E,V213G,G339D,I358V,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.35 853 13 1.5% 1 +[H69-,V70-,K147E,V213G,T284I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.11 852 665 78.1% 0 +[V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.11 852 47 5.5% 1 +[V213G,G339D,L452R,Q493R,D1259H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.11 852 19 2.2% 1 +[V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.11 852 18 2.1% 1 +[V213G,G339D,L452R,Q493R,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.11 852 13 1.5% 1 +[F157L,V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.8 844 763 90.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.8 844 15 1.8% 1 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.8 844 12 1.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,G1251R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.8 844 7 0.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.8 844 4 0.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,S813I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.47 843 493 58.5% 0 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.47 843 51 6.0% 2 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V,T523N,D1165N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.47 843 33 3.9% 1 +[H69-,V70-,K147I,W152L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.47 843 16 1.9% 1 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.47 843 12 1.4% 1 +[H69-,V70-,K147I,W152R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BF.11.1 841 575 68.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.11.1 841 52 6.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.1 841 28 3.3% 1 +[Q14R,H69-,V70-,V213G,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.1 841 24 2.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.1 841 9 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1124V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.19 841 566 67.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.19 841 56 6.7% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.19 841 14 1.7% 10 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.19 841 11 1.3% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.19 841 11 1.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] FL.13 839 429 51.1% 0 (consensus) FL.13 839 99 11.8% 4 +[Q14H,K182E,F456L,E484K]-[E484A] FL.13 839 26 3.1% 1 +[F456L] FL.13 839 23 2.7% 1 -[K417N] FL.13 839 9 1.1% 5 +[Q14H,H146K,K182E,F456L,E484K]-[H146Q,E484A] A.23.1 839 268 31.9% 0 +[F157L,V367F,Q613H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.23.1 839 213 25.4% 1 +[R102I,F157L,V367F,Q613H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23.1 839 50 6.0% 1 +[F157L,V367F,Q613H,P681R,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23.1 839 49 5.8% 2 +[R102I,F157L,V367F,E484K,Q613H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23.1 839 35 4.2% 1 +[L141F,F157L,V367F,Q613H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.13.1 839 601 71.6% 0 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.13.1 839 57 6.8% 4 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.13.1 839 44 5.2% 1 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] JN.1.13.1 839 9 1.1% 1 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L,D1168G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.13.1 839 7 0.8% 1 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] BF.12 837 715 85.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.12 837 24 2.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.12 837 6 0.7% 1 +[H69-,V70-,T95I,V213G,G339D,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.12 837 5 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486I]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.12 837 5 0.6% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.6.6 835 710 85.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6.6 835 17 2.0% 1 +[D1118V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.6 835 9 1.1% 1 +[S1249Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.6 835 8 1.0% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.6 835 5 0.6% 1 +[F490L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.8 833 194 23.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.8 833 106 12.7% 1 +[V227L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.8 833 95 11.4% 2 +[M153I,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.8 833 35 4.2% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.8 833 34 4.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.153 832 580 69.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.153 832 39 4.7% 1 +[T1120I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.153 832 33 4.0% 1 +[F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.153 832 17 2.0% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.153 832 15 1.8% 1 +[H625Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.84 831 340 40.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.84 831 281 33.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.84 831 29 3.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.84 831 13 1.6% 2 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.84 831 11 1.3% 2 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619 830 525 63.3% 0 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.619 830 53 6.4% 1 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619 830 51 6.1% 1 +[I210T,E484K,A879S,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619 830 34 4.1% 1 +[L5F,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619 830 14 1.7% 1 +[I128V,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.46 827 540 65.3% 0 (consensus) XBB.1.5.46 827 36 4.4% 2 -[R408S,S477N] XBB.1.5.46 827 27 3.3% 1 +[H146K]-[H146Q] XBB.1.5.46 827 21 2.5% 1 -[K417N] XBB.1.5.46 827 16 1.9% 1 +[L5F] B.1.371 827 745 90.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.371 827 15 1.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.371 827 14 1.7% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.371 827 14 1.7% 1 +[L922F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.371 827 7 0.8% 1 +[S929I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.1 827 474 57.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.1 827 120 14.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.1 827 81 9.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.1 827 33 4.0% 1 +[T19R,S98F,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.1 827 7 0.8% 2 +[T19R,S98F,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.31 825 608 73.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.31 825 36 4.4% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.31 825 22 2.7% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.31 825 8 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.31 825 8 1.0% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.160.16 821 697 84.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.16 821 19 2.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.16 821 13 1.6% 2 +[T1027I,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.16 821 6 0.7% 1 +[D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.16 821 5 0.6% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.464 820 720 87.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.464 820 9 1.1% 1 +[L1244F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.464 820 7 0.9% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.464 820 7 0.9% 1 +[L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.464 820 6 0.7% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BU.1 818 628 76.8% 0 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BU.1 818 51 6.2% 1 +[H69-,V70-,V213G,S255F,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BU.1 818 15 1.8% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,F486P,F490S] BU.1 818 14 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BU.1 818 10 1.2% 1 +[H69-,V70-,V213G,G252D,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CH.1.1.24 814 486 59.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.24 814 31 3.8% 2 +[S71P,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q1180K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.24 814 30 3.7% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T572I,D1184N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.24 814 26 3.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.24 814 15 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.80 812 334 41.1% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.80 812 276 34.0% 1 +[T19R,T20I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.80 812 100 12.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.80 812 28 3.4% 1 +[T19R,R21T,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.80 812 16 2.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A701S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.7 810 683 84.3% 0 +[H69-,V70-,D80G,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.7 810 19 2.3% 1 +[H69-,V70-,D80G,V213G,G339D,L452R,F486V,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.7 810 9 1.1% 1 +[H69-,V70-,D80G,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.7 810 7 0.9% 1 +[H69-,V70-,D80G,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.7 810 5 0.6% 1 +[F2L,H69-,V70-,D80G,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EJ.2 810 614 75.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) EJ.2 810 14 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H,D1260E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.2 810 13 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] EJ.2 810 11 1.4% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.2 810 9 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,T250A,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] GK.2 809 515 63.7% 0 +[L455F,F456L,V511I] (consensus) GK.2 809 52 6.4% 2 +[L5F,F157L,L455F,F456L,V511I] GK.2 809 26 3.2% 1 +[N148T,L455F,F456L,V511I] GK.2 809 24 3.0% 1 +[K356T,L455F,F456L,V511I] GK.2 809 15 1.9% 2 +[K356T,L455F,F456L,V511I]-[H146Q] B.1.499 808 431 53.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.499 808 81 10.0% 1 +[E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.499 808 57 7.1% 1 +[A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.499 808 16 2.0% 2 +[A626S,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.499 808 15 1.9% 1 +[G181A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CK.2.1.1 807 580 71.9% 0 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.2.1.1 807 28 3.5% 1 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1.1 807 17 2.1% 1 +[H69-,V70-,V213G,S255F,T323I,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1.1 807 15 1.9% 1 +[H69-,V70-,V213G,T250I,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1.1 807 10 1.2% 1 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] XBB.1.5.19 807 522 64.7% 0 (consensus) XBB.1.5.19 807 40 5.0% 1 +[A411S] XBB.1.5.19 807 26 3.2% 1 +[F59L] XBB.1.5.19 807 19 2.4% 1 +[S98F] XBB.1.5.19 807 16 2.0% 1 +[N856S] BQ.1.25.1 805 655 81.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.25.1 805 13 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,M731I,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25.1 805 12 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L858I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25.1 805 11 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,R646H,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25.1 805 6 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L858I,K1045R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] HK.2 802 441 55.0% 0 +[Q14H,Q52H,L455F,F456L] (consensus) HK.2 802 145 18.1% 1 +[Q14H,Q52H,F456L] HK.2 802 7 0.9% 1 +[Q14H,T51I,Q52H,L455F,F456L] HK.2 802 6 0.7% 1 +[Q14H,Q52H,L455F,F456L,E780Q] HK.2 802 5 0.6% 2 +[Q14H,Q52H,L455F,F456L,A783S,E1144Q] B.1.177.42 800 713 89.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.42 800 35 4.4% 1 +[P26H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.42 800 9 1.1% 1 +[F140L,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.42 800 6 0.8% 1 +[A222V,T553I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.42 800 4 0.5% 1 +[A222V,V642G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.436 799 747 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.436 799 11 1.4% 1 +[G75V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.436 799 8 1.0% 1 +[K537R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.436 799 3 0.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.436 799 3 0.4% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.27 797 496 62.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.27 797 162 20.3% 1 +[A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.27 797 33 4.1% 1 +[T470N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.27 797 29 3.6% 1 +[V213M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.27 797 16 2.0% 2 +[D936G,A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.354 796 433 54.4% 0 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.354 796 36 4.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.354 796 25 3.1% 2 +[S12F,D138Y,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.354 796 22 2.8% 1 +[D138Y,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.354 796 18 2.3% 1 +[H66R,D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XCH.1 796 491 61.7% 0 +[L455F,F456L,T573I,S704L] (consensus) XCH.1 796 43 5.4% 1 +[L455F,F456L,T573I,Q677H,S704L] XCH.1 796 21 2.6% 1 +[L455F,F456L,T478R,T573I,S704L]-[T478K] XCH.1 796 16 2.0% 2 +[A222S,L455F,F456L,T478R,T573I,S704L]-[T478K] XCH.1 796 15 1.9% 1 +[H146K,L455F,F456L,T573I,S704L]-[H146Q] B.1.206 791 668 84.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.206 791 17 2.1% 2 +[A701V,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.206 791 13 1.6% 1 +[R1107S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.206 791 6 0.8% 1 +[A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.206 791 5 0.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.265 790 401 50.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.265 790 94 11.9% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.265 790 41 5.2% 1 +[D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.265 790 38 4.8% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.265 790 35 4.4% 2 +[P26L,Q314K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.24 790 458 58.0% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.24 790 39 4.9% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.24 790 22 2.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,L841F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.24 790 17 2.2% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,D574N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.24 790 15 1.9% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] CM.8.1 789 497 63.0% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] (consensus) CM.8.1 789 30 3.8% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,R403K,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1 789 10 1.3% 1 +[M153T,N164K,G181E,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1 789 8 1.0% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,D1118Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1 789 8 1.0% 1 +[T29I,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] BA.1.12 789 681 86.3% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.12 789 14 1.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,R1185H]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.12 789 13 1.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.12 789 11 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S,N764K] BA.1.12 789 6 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,Q1113L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] CP.1 788 570 72.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.1 788 61 7.7% 1 +[P9L,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.1 788 14 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] CP.1 788 12 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CP.1 788 12 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] ED.2 787 501 63.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) ED.2 787 63 8.0% 1 +[H69-,V70-,G181V,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.2 787 56 7.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.2 787 21 2.7% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.2 787 12 1.5% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.66 787 517 65.7% 0 (consensus) XBB.1.5.66 787 17 2.2% 1 +[T478R]-[T478K] XBB.1.5.66 787 14 1.8% 1 -[K417N] XBB.1.5.66 787 12 1.5% 1 +[H146K]-[H146Q] XBB.1.5.66 787 9 1.1% 1 +[T208M] FL.10 785 462 58.9% 0 (consensus) FL.10 785 25 3.2% 1 +[T51I] FL.10 785 19 2.4% 1 -[R408S] FL.10 785 17 2.2% 2 +[K356T,T523N] FL.10 785 14 1.8% 1 -[G142D] JN.1.4.2 778 574 73.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.4.2 778 35 4.5% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.2 778 28 3.6% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.2 778 6 0.8% 1 +[+16MPLF,R21T,G35R,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.2 778 5 0.6% 5 +[+16MPLF,R21T,S50L,A67S,H69-,V70-,V127F,F157S,R158G,N185D,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] AZ.1 778 635 81.6% 0 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AZ.1 778 89 11.4% 1 +[T95I,A222V,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.1 778 9 1.2% 1 +[T95I,E180D,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.1 778 5 0.6% 1 +[T95I,E484K,S680F,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.1 778 5 0.6% 1 +[T95I,E484K,T678I,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] DT.2 777 685 88.2% 0 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DT.2 777 7 0.9% 1 +[L5F,H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.2 777 6 0.8% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K,G1124D]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.2 777 5 0.6% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.2 777 4 0.5% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K,V1230M]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DF.1 777 570 73.4% 0 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DF.1 777 36 4.6% 1 +[H69-,V70-,F157L,V213G,A262S,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DF.1 777 22 2.8% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V,P1263R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DF.1 777 14 1.8% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DF.1 777 12 1.5% 2 +[H69-,V70-,V213G,A262S,G339D,G446V,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] A.2 776 557 71.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2 776 53 6.8% 1 +[I197V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2 776 25 3.2% 1 +[Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2 776 14 1.8% 9 +[L141-,G142-,V143-,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2 776 9 1.2% 5 +[L141-,G142-,V143-,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3 772 713 92.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.3 772 21 2.7% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3 772 5 0.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3 772 3 0.4% 1 +[A879T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3 772 3 0.4% 1 +[W64L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.1.2 770 581 75.5% 0 +[Q613H] (consensus) EG.1.2 770 25 3.2% 1 +[P479R,Q613H] EG.1.2 770 21 2.7% 1 +[Q613H,P1162S] EG.1.2 770 8 1.0% 1 +[Q613H,E654D] EG.1.2 770 7 0.9% 1 +[P85L,Q613H] EG.1.4 767 514 67.0% 0 +[Q613H] (consensus) EG.1.4 767 16 2.1% 1 +[D215H,Q613H] EG.1.4 767 15 2.0% 1 +[Q613H]-[R408S] EG.1.4 767 14 1.8% 1 +[H146K,Q613H]-[H146Q] EG.1.4 767 12 1.6% 1 +[M177T,Q613H] AY.4.13 766 508 66.3% 0 +[T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.13 766 48 6.3% 1 +[T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.13 766 31 4.0% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.13 766 17 2.2% 1 +[T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,D950N,D1165Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.13 766 15 2.0% 1 +[T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,S937T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.1 761 286 37.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.1 761 212 27.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.1 761 34 4.5% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.1 761 25 3.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.36.1 761 16 2.1% 1 +[Q779L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.11.2 760 550 72.4% 0 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.11.2 760 59 7.8% 1 +[H69-,V70-,T76I,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.2 760 26 3.4% 1 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V,I598V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.2 760 24 3.2% 1 +[L5F,H69-,V70-,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.2 760 17 2.2% 2 +[H69-,V70-,K147N,V213G,V320F,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.375 755 489 64.8% 0 +[H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.375 755 86 11.4% 1 +[H69-,V70-,C1236S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.375 755 70 9.3% 1 +[H69-,V70-,S477R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.375 755 14 1.9% 1 +[H69-,V70-,V622I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.375 755 6 0.8% 1 +[H49Y,H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.551 752 256 34.0% 0 +[P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.551 752 213 28.3% 2 +[S254F,P681R,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.551 752 86 11.4% 1 +[S98F,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.551 752 50 6.6% 1 +[T95A,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.551 752 14 1.9% 3 +[S254F,P681R,T747I,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.18.1 752 234 31.1% 0 (consensus) XBB.1.18.1 752 95 12.6% 1 -[R346T] XBB.1.18.1 752 59 7.8% 2 -[R346T,K417N] XBB.1.18.1 752 27 3.6% 2 +[F456L]-[R346T] XBB.1.18.1 752 21 2.8% 3 +[F456L,H1083Y]-[R346T] BA.2.23.1 751 653 87.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.23.1 751 23 3.1% 1 +[V213G,G257D,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23.1 751 10 1.3% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23.1 751 8 1.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.23.1 751 6 0.8% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.20 751 238 31.7% 0 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.20 751 236 31.4% 4 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.20 751 12 1.6% 5 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.20 751 11 1.5% 5 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.20 751 10 1.3% 5 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.3.10 751 672 89.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.10 751 8 1.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.10 751 8 1.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.3.10 751 6 0.8% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.10 751 6 0.8% 1 +[V213G,G339D,Q493R,P1143S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.15.1.1 750 406 54.1% 0 +[L455F,F456L,A475V] (consensus) FL.15.1.1 750 30 4.0% 1 +[P251H,L455F,F456L,A475V] FL.15.1.1 750 21 2.8% 2 +[P251H,L455F,F456L,A475V,E583K] FL.15.1.1 750 20 2.7% 2 +[K182I,Q183D,L455F,F456L,A475V]-[Q183E] FL.15.1.1 750 18 2.4% 1 +[N148T,L455F,F456L,A475V] BF.7.14.1 750 368 49.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14.1 750 215 28.7% 1 +[H69-,V70-,V83F,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.1 750 10 1.3% 2 +[H69-,V70-,V83F,V213G,G339D,L452R,F486V,T739A,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.1 750 8 1.1% 3 +[H69-,V70-,V83F,V213G,E309Q,G339D,L452R,F486V,N1187S,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.1 750 6 0.8% 1 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.568 749 595 79.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.568 749 19 2.5% 1 +[P561S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.568 749 9 1.2% 1 +[K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.568 749 8 1.1% 1 +[D80N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.568 749 8 1.1% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.24 748 670 89.6% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.24 748 32 4.3% 1 +[R214L,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.24 748 7 0.9% 1 +[A222V,E1262A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.24 748 4 0.5% 1 +[A222V,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.24 748 4 0.5% 1 +[H69Y,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.3.3 748 451 60.3% 0 +[K182N,D253G,P521S]-[G252V] (consensus) XBB.2.3.3 748 18 2.4% 1 +[H146K,K182N,D253G,P521S]-[H146Q,G252V] XBB.2.3.3 748 12 1.6% 1 +[K182N,D253G,P521S]-[G252V,K417N] XBB.2.3.3 748 11 1.5% 1 +[K182N,D253G,F456L,P521S]-[G252V] XBB.2.3.3 748 10 1.3% 1 +[K182N,D253G,S494P,P521S]-[G252V] B.1.239 747 344 46.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.239 747 128 17.1% 2 +[L18F,P251H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.239 747 38 5.1% 1 +[R237S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.239 747 30 4.0% 1 +[D178N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.239 747 17 2.3% 1 +[I233V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GK.2.1 739 451 61.0% 0 +[L455F,F456L,V511I] (consensus) GK.2.1 739 33 4.5% 2 +[Q14R,L455F,F456L,V511I,V1264L] GK.2.1 739 22 3.0% 1 +[K304N,L455F,F456L,V511I] GK.2.1 739 13 1.8% 1 +[L455F,F456L] GK.2.1 739 9 1.2% 1 +[H146K,L455F,F456L,V511I]-[H146Q] BA.2.3.4 738 679 92.0% 0 +[V213G,G339D,Q493R,N641S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.4 738 9 1.2% 1 +[V213G,G339D,Q493R,N641S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.4 738 4 0.5% 1 +[V213G,G339D,Q493R,N641S,S943G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.4 738 4 0.5% 1 +[V213G,G339D,K444R,Q493R,N641S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.4 738 4 0.5% 1 +[V213G,G339D,Q493R,N641S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.351.2 737 387 52.5% 0 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.351.2 737 53 7.2% 1 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V,I934V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.2 737 25 3.4% 1 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V,I1232F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.2 737 19 2.6% 2 +[L18F,G75V,D80A,D215G,L242-,A243-,L244-,E484K,A701V,I934V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.2 737 15 2.0% 1 +[L18F,D80A,E180G,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.10 733 558 76.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.10 733 21 2.9% 2 +[S221L,T250A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.10 733 19 2.6% 1 +[M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.10 733 17 2.3% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.10 733 7 1.0% 3 +[H69-,V70-,S221L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.346 732 615 84.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.346 732 17 2.3% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.346 732 8 1.1% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.346 732 8 1.1% 2 +[D287G,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.346 732 7 1.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BR.2 729 457 62.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BR.2 729 150 20.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I,S730F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2 729 15 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,T240I,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2 729 8 1.1% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,A348S,L452R,F486I,S730F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2 729 8 1.1% 2 +[A27-,K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I]-[L24-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.333 727 650 89.4% 0 +[L54F,D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.333 727 15 2.1% 1 +[L54F,D138Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.333 727 9 1.2% 1 +[L54F,D138Y,T547I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.333 727 9 1.2% 1 +[S12F,L54F,D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.333 727 5 0.7% 1 +[L54F,D138Y,T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.301 726 401 55.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.301 726 140 19.3% 1 +[V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.301 726 95 13.1% 2 +[L5F,V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.301 726 18 2.5% 2 +[A222V,V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.301 726 13 1.8% 2 +[I68T,V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.6.1 722 604 83.7% 0 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.6.1 722 8 1.1% 2 +[H69-,V70-,W152L,V213G,G257S,G339D,L452R,F486V,N658S,D1168Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.1 722 7 1.0% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V,N658S,D1163Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.1 722 6 0.8% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,E484V,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,E484A,F486P,F490S] BA.4.6.1 722 5 0.7% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V,N658S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.24 721 270 37.4% 0 +[H69-,V70-,V213G,T240I,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.24 721 225 31.2% 1 +[H69-,V70-,V213G,T240I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.24 721 55 7.6% 1 +[H69-,V70-,V213G,T240I,G339D,K444T,L452R,F486V,A701V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.24 721 52 7.2% 1 +[H69-,V70-,V213G,T240I,S255F,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.24 721 27 3.7% 2 +[F32V,H69-,V70-,V213G,T240I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.3.18 721 327 45.4% 0 +[V213G,G339D,Q493R,I692F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.18 721 326 45.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.18 721 4 0.6% 2 +[V213G,G339D,Q493R,A706V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.18 721 4 0.6% 1 +[V213G,G339D,Q493R,I692F,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.18 721 4 0.6% 1 +[I197V,V213G,G339D,Q493R,I692F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.4.1 719 602 83.7% 0 +[F486S,S673G,T883I]-[F486P] (consensus) XBB.1.4.1 719 14 1.9% 1 +[F486S,S673G,T883I,L938F]-[F486P] XBB.1.4.1 719 6 0.8% 1 +[F486S,S673G,T883I]-[K417N,F486P] XBB.1.4.1 719 6 0.8% 1 +[H245Y,F486S,S673G,T883I]-[F486P] XBB.1.4.1 719 5 0.7% 1 +[N354K,F486S,S673G,T883I]-[F486P] BQ.1.1.28 719 540 75.1% 0 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.28 719 52 7.2% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.28 719 12 1.7% 1 +[H69-,V70-,V213G,P251L,S255F,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.28 719 11 1.5% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.28 719 10 1.4% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,A684V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.93 719 648 90.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.93 719 10 1.4% 1 +[A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.93 719 9 1.3% 1 +[D1146H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.93 719 5 0.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.93 719 5 0.7% 1 +[V62L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.111 718 214 29.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.111 718 176 24.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.111 718 67 9.3% 1 +[W152R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.111 718 28 3.9% 3 +[L249S,E484K,F1121L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.111 718 18 2.5% 1 +[D215G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GY.5 718 510 71.0% 0 +[E180V,T478R]-[T478K] (consensus) GY.5 718 14 1.9% 1 +[E180V,T478R]-[K417N,T478K] GY.5 718 14 1.9% 1 +[H146K,E180V,T478R]-[H146Q,T478K] GY.5 718 12 1.7% 1 +[E180V,Q218P,T478R]-[T478K] GY.5 718 11 1.5% 1 +[E180V,T478R,T573I]-[T478K] AY.4.2.5 715 609 85.2% 0 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2.5 715 48 6.7% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,L452R,P681R,M731I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.5 715 11 1.5% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,G446D,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.5 715 5 0.7% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.5 715 4 0.6% 1 +[L5F,T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.6 711 583 82.0% 0 +[L18F,Q23H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.6 711 22 3.1% 1 +[L18F,Q23H,D215Y,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.6 711 22 3.1% 1 +[L18F,Q23H,A222V,A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.6 711 17 2.4% 2 +[L18F,Q23H,A222V,G446V,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.6 711 10 1.4% 1 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.170 706 487 69.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.170 706 86 12.2% 1 +[E583Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.170 706 40 5.7% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.170 706 6 0.8% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.170 706 5 0.7% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.44 705 536 76.0% 0 +[V213G,G339D,S371Y,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.44 705 57 8.1% 1 +[L176F,V213G,G339D,S371Y,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] BA.2.44 705 22 3.1% 1 +[V213G,G339D,S371Y,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.44 705 6 0.9% 1 +[V213G,G339D,S371Y,K444R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] BA.2.44 705 6 0.9% 1 +[V213G,G339D,S371Y,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S,P681H] EG.4 704 510 72.4% 0 (consensus) EG.4 704 19 2.7% 1 +[H146K]-[H146Q] EG.4 704 10 1.4% 1 -[K417N] EG.4 704 7 1.0% 2 +[H146K,S256L]-[H146Q] EG.4 704 7 1.0% 2 +[S256L]-[Y144-] XDD 703 398 56.6% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDD 703 86 12.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD 703 26 3.7% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD 703 8 1.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD 703 8 1.1% 1 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.50 703 650 92.5% 0 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.50 703 13 1.8% 1 +[L212S,V213G,G339D,Q493R,E1151D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.50 703 7 1.0% 1 +[L212S,V213G,G339D,Q493R,I624T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.50 703 4 0.6% 1 +[S98F,L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.50 703 3 0.4% 1 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.26 701 254 36.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.26 701 180 25.7% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.26 701 36 5.1% 3 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,L822F,C1250F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.26 701 34 4.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,K1245R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.26 701 21 3.0% 1 +[H69-,V70-,H146-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EE.2 700 394 56.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EE.2 700 115 16.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.2 700 64 9.1% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.2 700 13 1.9% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.2 700 5 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A1078T]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.16.19 700 451 64.4% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.19 700 15 2.1% 1 +[E180V,T323I,T478R]-[T478K] XBB.1.16.19 700 14 2.0% 1 +[T76A,E180V,T478R]-[T478K] XBB.1.16.19 700 12 1.7% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.19 700 11 1.6% 2 +[E180V,T478R,S810L,E1150D]-[T478K] B.1.22 699 536 76.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.22 699 40 5.7% 1 +[D215G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.22 699 34 4.9% 2 +[L452M,F486L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.22 699 15 2.1% 1 +[A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.22 699 6 0.9% 1 +[F486L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.5 699 243 34.8% 0 +[K1181I] (consensus) XBB.1.5.5 699 140 20.0% 1 +[G181V,K1181I] XBB.1.5.5 699 111 15.9% 1 +[T523A,K1181I] XBB.1.5.5 699 29 4.1% 2 +[E471Q,T523A,K1181I] XBB.1.5.5 699 11 1.6% 1 +[K1181I]-[K417N] B.6 698 554 79.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6 698 21 3.0% 1 +[K77M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6 698 20 2.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6 698 16 2.3% 3 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.6 698 6 0.9% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] EE.1 696 547 78.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EE.1 696 18 2.6% 1 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.1 696 15 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.1 696 10 1.4% 1 +[H69-,V70-,P209L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.1 696 9 1.3% 2 +[H69-,V70-,S112L,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.1.1.6 696 620 89.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.6 696 22 3.2% 1 +[A67V,H69-,V70-,T76I,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.6 696 18 2.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,S254F,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.6 696 4 0.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,I1169V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.6 696 3 0.4% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] GE.1.2 696 368 52.9% 0 +[K77R,N148T,N185I,F186-,D253G,+374F,T376-,P521S]-[G252V,S375F,T376A,T478K] (consensus) GE.1.2 696 73 10.5% 5 +[N148T,N185I,F186-,D253G,T478R,P521S]-[G252V,T478K] GE.1.2 696 18 2.6% 1 +[K77R,N148T,N185I,F186-,D253G,+374F,T376-,P521S,Q1201K]-[G252V,S375F,T376A,T478K] GE.1.2 696 10 1.4% 2 +[N148T,M153I,N185I,F186-,D253G,+374F,T376-,P521S]-[G252V,S375F,T376A,T478K] GE.1.2 696 10 1.4% 1 +[N148T,N185I,F186-,D253G,+374F,T376-,P521S]-[G252V,S375F,T376A,T478K] JN.1.43.1 695 474 68.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.43.1 695 47 6.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.43.1 695 10 1.4% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] JN.1.43.1 695 8 1.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.43.1 695 7 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,G142Y,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBB.1.5.14 692 420 60.7% 0 (consensus) XBB.1.5.14 692 46 6.6% 1 +[A163S] XBB.1.5.14 692 12 1.7% 2 +[T19L,Q675H]-[T19I] XBB.1.5.14 692 11 1.6% 1 +[D1153Y] XBB.1.5.14 692 11 1.6% 1 +[H146K]-[H146Q] B.1.1.189 692 171 24.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.189 692 155 22.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.189 692 47 6.8% 1 +[E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.189 692 28 4.0% 1 +[V483F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.189 692 14 2.0% 2 +[N282D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.72 689 500 72.6% 0 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.72 689 55 8.0% 1 +[L212S,V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.72 689 23 3.3% 1 +[L212S,V213G,G339D,Q493R,T632N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.72 689 22 3.2% 1 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.72 689 6 0.9% 1 +[L5F,L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DU.1 689 475 68.9% 0 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,E1144Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DU.1 689 67 9.7% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,E1144Q,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DU.1 689 24 3.5% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DU.1 689 12 1.7% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,T1117I,E1144Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DU.1 689 12 1.7% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,L922F,E1144Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BE.5 686 504 73.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.5 686 37 5.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.5 686 33 4.8% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.5 686 18 2.6% 2 +[H69-,V70-,G75V,W152L,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.5 686 9 1.3% 1 +[H69-,V70-,V213G,P251L,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.71 684 278 40.6% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.71 684 180 26.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.71 684 28 4.1% 1 +[T19R,T20I,E156G,F157-,R158-,A222V,L452R,P681R,D950N,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.71 684 11 1.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.71 684 10 1.5% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.6 683 444 65.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.6 683 87 12.7% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.6 683 7 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.6 683 7 1.0% 6 +[R21T,S50L,H69-,V70-,V127F,M153K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.6 683 5 0.7% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S689N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] Q.7 682 415 60.9% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.7 682 133 19.5% 1 +[H69-,V70-,M177T,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.7 682 23 3.4% 1 +[H69-,V70-,A570D,Q677H,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.7 682 11 1.6% 2 +[S12F,H69-,V70-,A570D,T678I,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.7 682 8 1.2% 1 +[H69-,V70-,W258S,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.177.18 681 593 87.1% 0 +[A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.18 681 14 2.1% 1 +[T76I,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.18 681 12 1.8% 1 +[A222V,D427G,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.18 681 10 1.5% 1 +[A222V,E484Q,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.18 681 7 1.0% 1 +[L5F,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.14 678 545 80.4% 0 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.14 678 44 6.5% 1 +[L18F,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.14 678 15 2.2% 1 +[M153I,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.14 678 4 0.6% 1 +[N439K,G1219S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.14 678 4 0.6% 1 +[A67V,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.11 678 492 72.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.11 678 30 4.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.11 678 29 4.3% 1 +[T19R,T95I,I100L,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.11 678 13 1.9% 1 +[T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.11 678 10 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1191M]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.620 678 475 70.1% 0 +[P26S,H69-,V70-,V126A,L242-,A243-,L244-,H245Y,E484K,T1027I,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.620 678 26 3.8% 4 +[P26S,H69-,V70-,V126A,E484K,T1027I,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.620 678 18 2.7% 1 +[P26S,H69-,V70-,V126A,N137S,L242-,A243-,L244-,H245Y,E484K,T1027I,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.620 678 12 1.8% 1 +[P26S,H69-,V70-,V126A,L242-,A243-,L244-,H245Y,E484K,T1027I,D1118H,V1133F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.620 678 8 1.2% 1 +[P26S,H69-,V70-,V126A,L242-,A243-,L244-,H245Y,E484K,T1027I,D1118H,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BN.1.1 676 492 72.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.1 676 9 1.3% 1 +[I68V,K147E,W152R,F157L,I210V,V213G,G257S,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.1 676 9 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.1 676 8 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G261A,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.1 676 6 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S494P,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBB.1.5.65 673 384 57.1% 0 (consensus) XBB.1.5.65 673 30 4.5% 2 -[R408S,S477N] XBB.1.5.65 673 27 4.0% 1 +[E619Q] XBB.1.5.65 673 16 2.4% 1 +[R78M] XBB.1.5.65 673 14 2.1% 3 -[R408S,S477N,Q954H] GR.1 673 469 69.7% 0 +[E281D,V445S]-[V445P] (consensus) GR.1 673 26 3.9% 1 +[H146K,E281D,V445S]-[H146Q,V445P] GR.1 673 19 2.8% 1 +[G75S,E281D,V445S]-[V445P] GR.1 673 13 1.9% 1 +[L249F,E281D,V445S]-[V445P] GR.1 673 12 1.8% 1 +[N148T,E281D,V445S]-[V445P] B.1.1.279 672 592 88.1% 0 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.279 672 35 5.2% 1 +[R21I,L841R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.279 672 11 1.6% 1 +[R21I,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.279 672 4 0.6% 1 +[R21I,N211S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.279 672 3 0.4% 1 +[R21I,S255P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.28 671 485 72.3% 0 +[H69-,V70-,V213G,Y248S,+248RWMD,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.28 671 86 12.8% 5 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.28 671 11 1.6% 1 +[T19L,H69-,V70-,V213G,Y248S,+248RWMD,G339D,K444T,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.28 671 5 0.7% 1 +[H69-,V70-,V213G,Y248S,+248RWMD,G339D,K444T,L452R,F486V,E554Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.28 671 4 0.6% 1 +[H69-,V70-,V213G,Y248S,+248RWMD,G339D,K444T,L452R,F486V,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BF.9 670 595 88.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.9 670 24 3.6% 1 +[H69-,V70-,N185S,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.9 670 6 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.9 670 3 0.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1124V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.9 670 3 0.4% 1 +[T22I,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.377 669 540 80.7% 0 +[I233V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.377 669 86 12.9% 1 +[I233V,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.377 669 13 1.9% 1 +[I233V,G257S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.377 669 4 0.6% 1 +[I233V,V267L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.377 669 3 0.4% 1 +[I233V,T676P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.134 669 624 93.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.134 669 9 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,L841I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.134 669 4 0.6% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.134 669 3 0.4% 1 +[S13I,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.134 669 3 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.43 668 459 68.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.43 668 53 7.9% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.43 668 12 1.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1127E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.43 668 7 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] JN.1.43 668 6 0.9% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BN.1.2.1 668 529 79.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T470N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.1 668 9 1.3% 1 +[L8F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,T470N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.1 668 9 1.3% 1 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,K356T,T470N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.1 668 8 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T470N,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.1 668 6 0.9% 2 +[K147E,W152R,F157L,I210V,V213G,K356T,T470N]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] C.16 667 240 36.0% 0 +[L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.16 667 121 18.1% 1 +[L452R,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.16 667 58 8.7% 3 +[L452R,S640F,G769V,K854N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.16 667 25 3.7% 1 +[A411S,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.16 667 21 3.1% 1 +[L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.432 667 264 39.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.432 667 35 5.2% 1 +[A647V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.432 667 28 4.2% 1 +[T618S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.432 667 25 3.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.432 667 24 3.6% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.22 664 327 49.2% 0 +[G181V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.22 664 176 26.5% 1 +[L18F,G181V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.22 664 57 8.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.22 664 21 3.2% 2 +[L18F,G181V,A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.22 664 6 0.9% 2 +[L18F,G181V,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.524 663 513 77.4% 0 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.524 663 41 6.2% 1 +[R214L,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.524 663 10 1.5% 1 +[L452M,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.524 663 6 0.9% 3 +[R214L,E654A,A701V,T791I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.524 663 5 0.8% 2 +[R214L,A701V,L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.14.5 663 513 77.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14.5 663 23 3.5% 1 +[H69-,V70-,V213G,R214L,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.5 663 6 0.9% 1 +[H69-,V70-,E96A,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.5 663 5 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F,G1267R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.5 663 4 0.6% 2 +[H69-,V70-,K182N,V213G,G339D,R346I,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.18 662 413 62.4% 0 (consensus) FL.18 662 22 3.3% 1 +[R78M] FL.18 662 20 3.0% 1 -[K417N] FL.18 662 15 2.3% 1 -[T478K] FL.18 662 12 1.8% 2 +[V1068I]-[T478K] BA.1.1.9 661 553 83.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.9 661 58 8.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.9 661 11 1.7% 1 +[A67V,H69-,V70-,T95I,F140L,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.9 661 3 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,Q677K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.9 661 3 0.5% 1 +[S12F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.86 659 429 65.1% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.86 659 122 18.5% 1 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.86 659 23 3.5% 1 +[T19R,D80G,E156G,F157-,R158-,L452R,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.86 659 12 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.86 659 10 1.5% 1 +[T19R,E156G,F157-,R158-,L452R,Y660H,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.17 658 260 39.5% 0 +[S12F,L452R,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.17 658 86 13.1% 2 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.17 658 40 6.1% 1 +[L452R,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.17 658 16 2.4% 3 +[H49Y,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.17 658 14 2.1% 1 +[S12F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.23 657 303 46.1% 0 (consensus) XBB.1.5.23 657 54 8.2% 1 +[H146K]-[H146Q] XBB.1.5.23 657 37 5.6% 1 +[H245Y] XBB.1.5.23 657 33 5.0% 1 -[R408S] XBB.1.5.23 657 22 3.3% 1 +[T19L]-[T19I] P.1.7.1 656 520 79.3% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] (consensus) P.1.7.1 656 15 2.3% 1 +[L5F,L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7.1 656 13 2.0% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E583D,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7.1 656 9 1.4% 2 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E583D,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7.1 656 8 1.2% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,K444N,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] BE.1.3 654 472 72.2% 0 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.3 654 66 10.1% 1 +[H69-,V70-,K147N,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.3 654 22 3.4% 1 +[L5F,H69-,V70-,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.3 654 11 1.7% 2 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.3 654 7 1.1% 1 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.160.8 651 561 86.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.8 651 36 5.5% 1 +[D1084E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.8 651 10 1.5% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.8 651 10 1.5% 2 +[P26S,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.8 651 5 0.8% 3 +[P26S,E484D,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.10.1 649 433 66.7% 0 +[A344T,R403K,S494P,A701V] (consensus) EG.10.1 649 22 3.4% 1 +[H146K,A344T,R403K,S494P,A701V]-[H146Q] EG.10.1 649 9 1.4% 1 +[A344T,S494P,A701V] EG.10.1 649 8 1.2% 1 +[A344T,R403K,S494P,A701V]-[K417N] EG.10.1 649 6 0.9% 1 +[A344T,R403K,S494P,A701V,D1260N] CR.1.1 648 519 80.1% 0 +[V62I,H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CR.1.1 648 15 2.3% 1 +[V62I,H69-,V70-,V213G,G339D,K444R,L452R,F486V,S940A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1.1 648 14 2.2% 1 +[V62I,H69-,V70-,V213G,G339D,T430I,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1.1 648 7 1.1% 2 +[V62I,H69-,V70-,F186Y,V213G,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1.1 648 6 0.9% 1 +[P9L,V62I,H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.91 644 199 30.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.91 644 158 24.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91 644 57 8.9% 2 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91 644 28 4.3% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91 644 20 3.1% 2 +[T19R,G75V,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FD.4 643 364 56.6% 0 (consensus) FD.4 643 44 6.8% 2 +[H146K,K182R]-[H146Q] FD.4 643 25 3.9% 1 +[P521S] FD.4 643 21 3.3% 2 +[T478R,T883I]-[T478K] FD.4 643 12 1.9% 3 +[H146K,K182R,T747I]-[H146Q] CN.1 642 361 56.2% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CN.1 642 166 25.9% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CN.1 642 13 2.0% 1 +[H69-,V70-,V213G,G252S,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CN.1 642 11 1.7% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,V1060I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CN.1 642 7 1.1% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.105 641 331 51.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.105 641 111 17.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.105 641 44 6.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.105 641 11 1.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.105 641 9 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,R214L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.58 640 505 78.9% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.58 640 27 4.2% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.58 640 14 2.2% 1 +[T29I,H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.58 640 10 1.6% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.58 640 9 1.4% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.8 639 387 60.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.8 639 154 24.1% 3 +[A262S,Q314K,F486L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.8 639 15 2.3% 1 +[T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.8 639 13 2.0% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.8 639 9 1.4% 1 +[A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.16 638 366 57.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.16 638 88 13.8% 1 +[V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.16 638 88 13.8% 3 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S373P,S375F,T376A,V445P,G446S,N460K,F486P,F490S] BA.2.3.16 638 8 1.3% 2 +[V213G,G339D,Q493R,G1251A]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.16 638 6 0.9% 1 +[V213G,G339D,K444R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.62 636 557 87.6% 0 +[L18F,T51I,A222V,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.62 636 16 2.5% 1 +[L18F,T51I,A222V,D936Y,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.62 636 10 1.6% 1 +[L5F,L18F,T51I,A222V,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.62 636 7 1.1% 1 +[L18F,T51I,T76I,A222V,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.62 636 6 0.9% 1 +[L18F,T51I,A222V,P337S,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.3 636 358 56.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.3 636 46 7.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3 636 17 2.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263T,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3 636 12 1.9% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3 636 11 1.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] BN.1.3.7 636 388 61.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.7 636 41 6.4% 1 +[G75S,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.7 636 27 4.2% 3 +[G75S,H146L,K147E,W152R,F157L,I210V,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F486P] BN.1.3.7 636 25 3.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V622F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.7 636 16 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T478R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,F486P] JD.2 636 487 76.6% 0 (consensus) JD.2 636 18 2.8% 1 -[R408S] JD.2 636 12 1.9% 2 -[R346T,K417N] JD.2 636 7 1.1% 1 -[R346T] JD.2 636 7 1.1% 1 +[H146K]-[H146Q] B.1.1.294 634 293 46.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.294 634 65 10.3% 2 +[T95I,A688S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.294 634 40 6.3% 1 +[E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.294 634 13 2.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.294 634 10 1.6% 2 +[E96D,L948I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.41.1 634 239 37.7% 0 +[L335S,R403K,T478R]-[T478K] (consensus) XBB.1.41.1 634 66 10.4% 1 +[Q173K,L335S,R403K,T478R]-[T478K] XBB.1.41.1 634 31 4.9% 1 +[L335S,R403K,T478R]-[R408S,T478K] XBB.1.41.1 634 29 4.6% 1 +[N148S,L335S,R403K,T478R]-[T478K] XBB.1.41.1 634 15 2.4% 1 +[L335S,G339R,R403K,T478R]-[G339H,T478K] EG.1.3 634 422 66.6% 0 +[Q613H] (consensus) EG.1.3 634 14 2.2% 1 +[D253Y,Q613H] EG.1.3 634 8 1.3% 1 +[H146K,Q613H]-[H146Q] EG.1.3 634 7 1.1% 2 +[A222V,D253Y,Q613H] EG.1.3 634 6 0.9% 1 +[Q613H]-[R408S] BN.1.9 633 487 76.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.9 633 16 2.5% 3 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.1.9 633 12 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.9 633 5 0.8% 1 +[V70L,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.9 633 5 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,H245Y,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] AY.58 631 450 71.3% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.58 631 54 8.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.58 631 27 4.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.58 631 17 2.7% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P479S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.58 631 8 1.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.70 628 164 26.1% 0 +[L455F,F456L] (consensus) XBB.1.5.70 628 35 5.6% 2 +[N185I,L455F,F456L,A475V] XBB.1.5.70 628 33 5.3% 3 +[K356T,L455F,F456L,A475V,E554G] XBB.1.5.70 628 32 5.1% 3 +[H146K,L455F,F456L,N556K,E583A]-[H146Q] XBB.1.5.70 628 25 4.0% 2 +[L455F,F456L]-[R346T,K417N] BA.2.33 627 546 87.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.33 627 25 4.0% 1 +[H66N,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.33 627 11 1.8% 1 +[V213G,G339D,Q493R,I1114T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.33 627 7 1.1% 1 +[V213G,R214L,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.33 627 6 1.0% 1 +[V213G,G339D,Q493R,T791I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.42 627 454 72.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.42 627 34 5.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704L,T747I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.42 627 14 2.2% 1 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.42 627 10 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.42 627 7 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBC.1 626 435 69.5% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1 626 24 3.8% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I,Q1208H]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1 626 23 3.7% 1 +[P25S,A67S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1 626 12 1.9% 2 +[P25S,A67S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1 626 10 1.6% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] B.1.280 625 512 81.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.280 625 9 1.4% 1 +[A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.280 625 8 1.3% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.280 625 7 1.1% 1 +[E406Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.280 625 6 1.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GS.4 624 391 62.7% 0 +[D253G,T478R,P521S]-[G252V,T478K] (consensus) GS.4 624 13 2.1% 1 +[H146K,D253G,T478R,P521S]-[H146Q,G252V,T478K] GS.4 624 13 2.1% 1 +[D253G,T478R]-[G252V,T478K] GS.4 624 10 1.6% 1 +[D253G,T478R,P521S]-[G252V,R408S,T478K] GS.4 624 7 1.1% 1 +[D253G,T478R,P521S,A701V]-[G252V,T478K] XBB.1.17.1 624 273 43.8% 0 +[D215H] (consensus) XBB.1.17.1 624 25 4.0% 1 +[H146K,D215H]-[H146Q] XBB.1.17.1 624 21 3.4% 1 +[D215H,T284I] XBB.1.17.1 624 15 2.4% 10 +[N148T,M177K,D178-,L179-,K182-,Q183-,G184-,D215H,Q218R,S494P,P521S]-[Q183E] XBB.1.17.1 624 13 2.1% 1 +[D215H,P812S] B.1.576 623 526 84.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.576 623 15 2.4% 1 +[G75V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.576 623 6 1.0% 2 +[T572I,K1181R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.576 623 5 0.8% 1 +[H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.576 623 4 0.6% 1 +[V70L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.2 623 456 73.2% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,Q675K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.9.2.2 623 40 6.4% 1 +[T19R,V70L,E156G,F157-,R158-,A222V,L452R,Q675K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.2 623 16 2.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q675K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.2 623 16 2.6% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,Q675K,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.2 623 14 2.2% 1 +[T19R,E156G,F157-,R158-,G181V,A222V,L452R,Q675K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.28 621 458 73.8% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,A701S,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.28 621 7 1.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,E484Q,P681R,A701S,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.28 621 7 1.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,A701S,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.28 621 5 0.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,T573I,P681R,A701S,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.28 621 4 0.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,A701S,D950N,A1078S,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.192 620 312 50.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.192 620 192 31.0% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.192 620 36 5.8% 1 +[F157S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.192 620 10 1.6% 2 +[F157S,T678A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.192 620 5 0.8% 1 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.18 620 505 81.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.18 620 21 3.4% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.18 620 16 2.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1199H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.18 620 11 1.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.18 620 4 0.6% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.12 619 363 58.6% 0 (consensus) FL.12 619 119 19.2% 1 +[D1084E] FL.12 619 11 1.8% 1 +[H146K]-[H146Q] FL.12 619 7 1.1% 1 -[K417N] FL.12 619 7 1.1% 1 +[G1085R] AY.43.9 618 326 52.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.9 618 151 24.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.9 618 42 6.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,N960K]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.9 618 16 2.6% 1 +[T19R,M153I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.9 618 6 1.0% 1 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HW.1 614 401 65.3% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) HW.1 614 45 7.3% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] HW.1 614 16 2.6% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,L822F]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] HW.1 614 16 2.6% 2 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,R346S,L452R,N703I,L822F]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] HW.1 614 7 1.1% 1 +[L5F,P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] AY.10 614 465 75.7% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.10 614 43 7.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.10 614 17 2.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.10 614 11 1.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.10 614 9 1.5% 2 +[T19R,I105V,E156G,F157-,R158-,A222V,A243S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.8.2 614 453 73.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.8.2 614 90 14.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.8.2 614 8 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.8.2 614 5 0.8% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619D,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,P681H] BQ.1.8.2 614 4 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619D,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] AY.32 612 303 49.5% 0 +[T19R,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.32 612 40 6.5% 1 +[T19R,E156G,F157-,R158-,T250I,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.32 612 31 5.1% 2 +[T19R,Y28F,E156G,F157-,R158-,L216F,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.32 612 27 4.4% 2 +[T19R,E156G,F157-,R158-,L452R,T572I,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.32 612 24 3.9% 1 +[T19R,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HN.1 612 383 62.6% 0 +[A67S,F456L,T478R,A701V]-[T478K] (consensus) HN.1 612 35 5.7% 1 +[A67S,H146K,F456L,T478R,A701V]-[H146Q,T478K] HN.1 612 24 3.9% 1 +[A67S,F456L,T478R,S691F,A701V]-[T478K] HN.1 612 23 3.8% 1 +[A67S,F456L,T478R,E554D,A701V]-[T478K] HN.1 612 9 1.5% 1 +[A67S,F456L,T478R,A701V,G842S]-[T478K] BQ.1.1.11 611 345 56.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.11 611 63 10.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P,Q1208H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.11 611 56 9.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.11 611 12 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.11 611 10 1.6% 2 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] P.1.13 610 546 89.5% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.13 610 5 0.8% 1 +[L18F,T20N,P25L,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.13 610 5 0.8% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.13 610 4 0.7% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F,G1223S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.13 610 3 0.5% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.12 610 531 87.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.12 610 27 4.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,S680F,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.12 610 16 2.6% 1 +[T19R,T95I,E156G,F157-,R158-,V193L,L452R,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.12 610 5 0.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T676I,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.12 610 3 0.5% 1 +[T19R,T95I,E156G,F157-,R158-,S256L,L452R,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.29 609 377 61.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.29 609 29 4.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.29 609 27 4.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.29 609 11 1.8% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] JN.1.29 609 11 1.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2 608 378 62.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KP.2 608 51 8.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2 608 12 2.0% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2 608 11 1.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2 608 9 1.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] B.1.361 608 494 81.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.361 608 35 5.8% 1 +[D1163G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.361 608 9 1.5% 1 +[P499S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.361 608 6 1.0% 1 +[A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.361 608 4 0.7% 1 +[T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.4.5 607 371 61.1% 0 (consensus) FL.4.5 607 24 4.0% 1 +[G181E] FL.4.5 607 15 2.5% 2 +[R190S,P521S] FL.4.5 607 15 2.5% 1 +[V952I] FL.4.5 607 14 2.3% 1 +[N856S] JN.1.8 605 344 56.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.8 605 42 6.9% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.8 605 20 3.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.8 605 14 2.3% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.8 605 9 1.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.1.17.1 605 557 92.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.17.1 605 6 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,A260T,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.1 605 6 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,R765L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.1 605 5 0.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.1 605 4 0.7% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] CK.1.4 604 501 82.9% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1.4 604 14 2.3% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] CK.1.4 604 13 2.2% 1 +[H69-,V70-,V213G,T307I,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.4 604 6 1.0% 1 +[H69-,V70-,V213G,G339D,S359N,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.4 604 5 0.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.1.17 602 447 74.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.17 602 26 4.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.17 602 17 2.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S940F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.17 602 10 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.17 602 5 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBB.1.5.62 602 329 54.7% 0 (consensus) XBB.1.5.62 602 20 3.3% 1 +[H1101Y] XBB.1.5.62 602 16 2.7% 1 +[H146K]-[H146Q] XBB.1.5.62 602 14 2.3% 1 +[E583Q] XBB.1.5.62 602 12 2.0% 1 +[W152R] BA.2.54 601 447 74.4% 0 +[V213G,Y248S,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.54 601 39 6.5% 1 +[V213G,Y248S,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.54 601 29 4.8% 1 +[V213G,Y248S,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.54 601 15 2.5% 1 +[V213G,Y248S,G339D,Q493R,E1202Q,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.54 601 11 1.8% 1 +[V213G,Y248S,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] B.1.428 601 408 67.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.428 601 45 7.5% 1 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428 601 35 5.8% 1 +[N481K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428 601 10 1.7% 2 +[D138Y,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428 601 9 1.5% 1 +[K97E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.39 600 548 91.3% 0 +[V213G,G339D,Q493R,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.39 600 8 1.3% 1 +[V213G,G339D,Q493R,L858I,G1219V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.39 600 6 1.0% 1 +[H49Y,V213G,G339D,Q493R,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.39 600 5 0.8% 1 +[V213G,G339D,Q493R,L858I,D950N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.39 600 4 0.7% 1 +[V213G,G339D,Q493R,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] JN.2.5 600 482 80.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.2.5 600 15 2.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,L249F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.5 600 15 2.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,G482S,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.5 600 11 1.8% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.5 600 7 1.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.177.20 599 557 93.0% 0 +[A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.20 599 10 1.7% 1 +[L141V,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.20 599 6 1.0% 1 +[M177I,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.20 599 5 0.8% 1 +[L5F,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.20 599 3 0.5% 1 +[A222V,E583D,P1263S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BM.1.1 598 358 59.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.1.1 598 26 4.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1 598 24 4.0% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1 598 17 2.8% 1 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1 598 12 2.0% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FY.1.2 597 174 29.1% 0 +[Y200C,T572I] (consensus) FY.1.2 597 75 12.6% 1 +[Y200C,T572I,V1129I] FY.1.2 597 56 9.4% 1 +[W64L,Y200C,T572I] FY.1.2 597 22 3.7% 1 +[W152R,Y200C,T572I] FY.1.2 597 21 3.5% 1 +[Y200C,D215H,T572I] BQ.1.1.29 597 340 57.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.29 597 115 19.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.29 597 12 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.29 597 10 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.29 597 7 1.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BE.4.1 597 365 61.1% 0 +[H69-,V70-,P209L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.4.1 597 55 9.2% 1 +[H69-,V70-,G181V,P209L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.1 597 14 2.3% 1 +[H69-,V70-,F135I,P209L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.1 597 14 2.3% 1 +[H69-,V70-,Q183L,P209L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.1 597 13 2.2% 1 +[H69-,V70-,P209L,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.33 595 381 64.0% 0 +[A222V,G639S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.33 595 69 11.6% 1 +[A222V,G639S,A672V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.33 595 38 6.4% 1 +[A222V,G639S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.33 595 10 1.7% 1 +[A222V,G639S,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.33 595 6 1.0% 1 +[L5F,A222V,G639S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.7 595 367 61.7% 0 +[K147E,W152R,F157L,M177T,+209V,N211G,L212-,V213-,G257S,K356T,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.7 595 81 13.6% 1 +[V62I,K147E,W152R,F157L,M177T,+209V,N211G,L212-,V213-,G257S,K356T,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.7 595 45 7.6% 1 +[K147E,W152R,F157L,M177T,+209V,N211G,L212-,V213-,G257S,K356T,N751D,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.7 595 14 2.4% 1 +[K147E,W152R,F157L,M177T,G181V,+209V,N211G,L212-,V213-,G257S,K356T,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.7 595 10 1.7% 1 +[K147E,W152R,F157L,M177T,+209V,N211G,L212-,V213-,G257S,K356T,H1101Y,I1114V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FY.3.2 595 434 72.9% 0 +[Y200C] (consensus) FY.3.2 595 14 2.4% 1 +[H146K,Y200C]-[H146Q] FY.3.2 595 9 1.5% 2 +[H69-,V70-,Y200C] FY.3.2 595 6 1.0% 1 +[L5F,Y200C] FY.3.2 595 4 0.7% 1 +[Y200C,A522V] AY.87 594 523 88.0% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.87 594 12 2.0% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.87 594 8 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.87 594 5 0.8% 3 +[T19R,E156G,F157-,R158-,L452R,N679T,S680R,P681-,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.87 594 4 0.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D936Y,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.8 593 339 57.2% 0 (consensus) FL.8 593 69 11.6% 1 +[S256L] FL.8 593 25 4.2% 1 +[D1084Y] FL.8 593 16 2.7% 2 +[S256L,E465D] FL.8 593 10 1.7% 1 -[K417N] B.1.177.83 592 259 43.8% 0 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.83 592 105 17.7% 1 +[A222V,A262S,P272L,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.83 592 72 12.2% 2 +[A222V,A262S,P272L,L452R,V1268I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.83 592 29 4.9% 1 +[A222V,A262S,P272L,L1224F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.83 592 7 1.2% 2 +[A222V,A262S,P272L,L452R,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.26 592 459 77.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.26 592 13 2.2% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.26 592 8 1.4% 4 +[I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.26 592 7 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.26 592 5 0.8% 1 +[K147E,W152R,F157L,M177I,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.160.30 591 432 73.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.30 591 46 7.8% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.30 591 15 2.5% 2 +[A879V,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.30 591 13 2.2% 1 +[S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.30 591 10 1.7% 1 +[K558N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.324 589 279 47.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.324 589 162 27.5% 1 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.324 589 16 2.7% 2 +[I1114L,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.324 589 13 2.2% 1 +[T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.324 589 9 1.5% 1 +[M153V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.22 587 265 45.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.22 587 72 12.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.22 587 62 10.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.22 587 29 4.9% 2 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,V608I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.22 587 8 1.4% 3 +[H69-,V70-,F157L,V213G,T307I,G339D,K444T,L452R,F486V,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.141 586 351 59.9% 0 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.141 586 40 6.8% 2 +[M153T,T385I,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.141 586 36 6.1% 1 +[M153T,N540S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.141 586 29 4.9% 1 +[M153T,T385I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.141 586 12 2.0% 1 +[M153T,Y351F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.88 583 184 31.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.88 583 86 14.8% 1 +[T19R,E156G,F157-,R158-,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.88 583 75 12.9% 2 +[T19R,T124S,E156G,F157-,R158-,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.88 583 25 4.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.88 583 22 3.8% 2 +[T19R,E156G,F157-,R158-,Q414R,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.32 582 474 81.4% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.32 582 11 1.9% 1 +[A222V,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.32 582 8 1.4% 1 +[W152L,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.32 582 5 0.9% 1 +[A222V,A871V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.32 582 5 0.9% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.24 581 485 83.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.24 581 18 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.24 581 14 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.24 581 8 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.24 581 5 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.4.1.4 579 449 77.5% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.4 579 27 4.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.4 579 19 3.3% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.1.4 579 15 2.6% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,I934V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.4 579 11 1.9% 1 +[V3G,H69-,V70-,A93S,V213G,G339D,L452R,F486V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] HZ.1 579 222 38.3% 0 +[T478R,P521T]-[T478K] (consensus) HZ.1 579 119 20.6% 1 +[T478R,P521T,S813N]-[T478K] HZ.1 579 32 5.5% 2 +[H146K,T478R,P521T,S813N]-[H146Q,T478K] HZ.1 579 29 5.0% 1 +[T478R,P521T,I1216V]-[T478K] HZ.1 579 25 4.3% 1 +[T478R,P521T,D796H]-[T478K,D796Y] A.27 578 318 55.0% 0 +[L18F,L452R,A653V,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] (consensus) A.27 578 79 13.7% 1 +[L18F,L452R,A653V,Q677H,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] A.27 578 26 4.5% 1 +[L18F,H49Y,L452R,A653V,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] A.27 578 17 2.9% 2 +[L18F,L452R,A653V,Q677H,K1191N,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] A.27 578 10 1.7% 1 +[L18F,L176F,L452R,A653V,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] BA.2.9.2 578 457 79.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.2 578 33 5.7% 2 +[H69-,V70-,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.2 578 30 5.2% 1 +[L179P,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.2 578 7 1.2% 1 +[V213G,G339D,Q493R,I1210V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.2 578 6 1.0% 1 +[V213G,G339D,Q493R,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.103.2 578 542 93.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.103.2 578 11 1.9% 1 +[T19R,E156G,F157-,R158-,E224A,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.2 578 5 0.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,T1116I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.2 578 3 0.5% 1 +[T19R,D138Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.2 578 3 0.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.177.19 578 550 95.2% 0 +[A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.19 578 4 0.7% 1 +[L5F,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.19 578 3 0.5% 1 +[A222V,E583D,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.19 578 3 0.5% 1 +[A222V,E583D,P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.19 578 2 0.3% 1 +[Q183R,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.9 577 475 82.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.9 577 36 6.2% 2 +[F32L,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.9 577 10 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.9 577 8 1.4% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.9 577 4 0.7% 1 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.433 576 494 85.8% 0 +[S477R,S673T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.433 576 22 3.8% 1 +[S477R,S673T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.433 576 17 3.0% 1 +[S477R,S673T,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.433 576 9 1.6% 1 +[S477R,S673T,G946V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.433 576 4 0.7% 1 +[V143F,S477R,S673T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] HK.8 576 247 42.9% 0 +[Q52H,L455F,F456L] (consensus) HK.8 576 129 22.4% 1 +[Q52H,L455F,F456L,D1153Y] HK.8 576 13 2.3% 1 +[Q52H,F157L,L455F,F456L] HK.8 576 13 2.3% 1 +[Q52H,H146K,L455F,F456L]-[H146Q] HK.8 576 12 2.1% 2 +[Q52H,S256L,L455F,F456L,D1153Y] AY.66 575 417 72.5% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.66 575 52 9.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.66 575 10 1.7% 1 +[T19R,E156G,F157-,R158-,A222V,V367I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.66 575 9 1.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,T1231A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.66 575 7 1.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,S1242N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.108 574 147 25.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.108 574 144 25.1% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.108 574 69 12.0% 1 +[T19R,T95I,E156G,F157-,R158-,Y248H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.108 574 22 3.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.108 574 16 2.8% 3 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362 573 353 61.6% 0 +[L452R,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.362 573 85 14.8% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362 573 38 6.6% 3 +[V1228A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362 573 8 1.4% 3 +[+256S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362 573 6 1.0% 1 +[A67V,L452R,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.3.1 573 441 77.0% 0 (consensus) FL.3.1 573 8 1.4% 1 +[S494P] FL.3.1 573 8 1.4% 1 +[H245Y] FL.3.1 573 7 1.2% 1 +[V1122L] FL.3.1 573 5 0.9% 1 +[H146K]-[H146Q] XBB.1.1 572 448 78.3% 0 +[F486S]-[F486P] (consensus) XBB.1.1 572 7 1.2% 2 +[V1228L]-[F486P] XBB.1.1 572 7 1.2% 1 +[F486S,P521T]-[F486P] XBB.1.1 572 6 1.0% 1 +[L5F,F486S]-[F486P] XBB.1.1 572 5 0.9% 1 +[F486S,E1111Q]-[F486P] B.1.160.17 571 465 81.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.17 571 58 10.2% 1 +[A942T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.17 571 18 3.2% 2 +[S373L,A942T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.17 571 7 1.2% 1 +[G75R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.17 571 2 0.4% 1 +[P384S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.41 570 411 72.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.41 570 27 4.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.41 570 17 3.0% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.41 570 16 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.41 570 12 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.4 570 491 86.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.4 570 9 1.6% 1 +[H69-,V70-,D138N,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.4 570 5 0.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.4 570 5 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.4 570 4 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.4 568 396 69.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3.4 568 44 7.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G769V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.4 568 23 4.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.3.4 568 14 2.5% 1 +[H69-,V70-,Q173H,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.4 568 9 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] EG.13 568 337 59.3% 0 (consensus) EG.13 568 28 4.9% 1 +[A623V] EG.13 568 13 2.3% 2 +[L176F,L1244F] EG.13 568 12 2.1% 1 +[L858I] EG.13 568 12 2.1% 1 +[H146K]-[H146Q] XBB.1.5.28 567 226 39.9% 0 +[T478R]-[T478K] (consensus) XBB.1.5.28 567 47 8.3% 1 +[T478R,C1247F]-[T478K] XBB.1.5.28 567 28 4.9% 1 +[Q183D,T478R]-[Q183E,T478K] XBB.1.5.28 567 22 3.9% 2 +[G181A,T478R,E619Q]-[T478K] XBB.1.5.28 567 21 3.7% 2 +[F157S,G252I,T478R]-[G252V,T478K] XBB.9 566 442 78.1% 0 +[F486S]-[G252V,F486P] (consensus) XBB.9 566 23 4.1% 1 +[F486S]-[G252V,K417N,F486P] XBB.9 566 17 3.0% 1 +[H146K,F486S]-[H146Q,G252V,F486P] XBB.9 566 8 1.4% 1 +[F486S]-[G252V,L368I,F486P] XBB.9 566 8 1.4% 1 +[S254F,F486S]-[G252V,F486P] XBB.1.5.47 565 347 61.4% 0 (consensus) XBB.1.5.47 565 11 1.9% 1 +[H146K]-[H146Q] XBB.1.5.47 565 9 1.6% 1 +[F456L] XBB.1.5.47 565 9 1.6% 1 +[H1058Y] XBB.1.5.47 565 9 1.6% 1 +[T259I] BM.4.1.1 563 377 67.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.4.1.1 563 30 5.3% 2 +[L5F,K147E,W152R,F157L,G181A,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.4.1.1 563 7 1.2% 2 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,F486S,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.4.1.1 563 7 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.4.1.1 563 6 1.1% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.9.1 562 480 85.4% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.1 562 36 6.4% 4 +[V213G,G339D,L452M,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.1 562 7 1.2% 1 +[V213G,H245N,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.1 562 4 0.7% 1 +[V213G,G339D,L452M,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.1 562 3 0.5% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.177.9 562 476 84.7% 0 +[D80Y,N164T,A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.9 562 25 4.4% 1 +[D80Y,T95I,N164T,A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.9 562 14 2.5% 1 +[D80Y,N164T,A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.9 562 7 1.2% 1 +[D80Y,N164T,A222V,A262S,I1216V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.9 562 5 0.9% 1 +[D80Y,S98F,N164T,A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.4 561 476 84.8% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) W.4 561 26 4.6% 1 +[A222V,A653V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.4 561 8 1.4% 1 +[P9S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.4 561 6 1.1% 1 +[A222V,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.4 561 6 1.1% 1 +[T22I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.74 560 426 76.1% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.74 560 16 2.9% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.74 560 16 2.9% 4 +[V213G,G339D,L452M,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.74 560 8 1.4% 1 +[L5F,V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.74 560 8 1.4% 1 +[V213G,G339D,L452M,Q493R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XDK 560 408 72.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDK 560 16 2.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDK 560 9 1.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDK 560 9 1.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] XDK 560 7 1.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.177.58 558 479 85.8% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.58 558 18 3.2% 1 +[L18F,G181V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.58 558 13 2.3% 1 +[L18F,A222V,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.58 558 12 2.2% 1 +[L18F,A222V,A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.58 558 7 1.3% 1 +[L18F,A222V,T604I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.5 556 461 82.9% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.5 556 21 3.8% 1 +[L18F,T22I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.5 556 20 3.6% 1 +[L18F,A222V,S689I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.5 556 6 1.1% 2 +[L18F,A222V,E484Q,S689I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.5 556 6 1.1% 1 +[L18F,G184V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.104 553 357 64.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.104 553 11 2.0% 1 +[T19R,R21I,T95I,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.104 553 8 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.104 553 7 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,F888L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.104 553 6 1.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,D950N,Q1180K]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.83 553 394 71.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.83 553 101 18.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.83 553 7 1.3% 1 +[T19R,R21I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.83 553 4 0.7% 2 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.83 553 3 0.5% 1 +[T19R,E156G,F157-,R158-,L452R,D574Y,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.391 553 478 86.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.391 553 31 5.6% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.391 553 4 0.7% 1 +[E471Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.391 553 3 0.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.391 553 2 0.4% 2 +[S255F,S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.269 552 478 86.6% 0 +[D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.269 552 15 2.7% 1 +[T95I,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.269 552 9 1.6% 1 +[L5F,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.269 552 4 0.7% 1 +[D936Y,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.269 552 3 0.5% 1 +[V143F,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DV.7.1.2 552 349 63.2% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.7.1.2 552 40 7.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,G485R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1.2 552 19 3.4% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,V772I,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1.2 552 7 1.3% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,R237K,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1.2 552 7 1.3% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,T791I,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BN.1.3.2 550 407 74.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.2 550 18 3.3% 4 +[I210V,V213G,G257S,K356T,V445A]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.2 550 15 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.2 550 11 2.0% 1 +[K147E,W152R,F157L,I210A,V213G,G257S,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.2 550 9 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A,N703S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.5.2.53 549 389 70.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.53 549 93 16.9% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.53 549 13 2.4% 1 +[H69-,V70-,V213G,L242F,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.53 549 6 1.1% 3 +[H69-,V70-,V213G,G339D,V445F,N450D,L452R,F486V,T547K,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.53 549 5 0.9% 1 +[H69-,V70-,V213G,S247N,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FK.1.3.2 549 383 69.8% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.3.2 549 21 3.8% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.3.2 549 8 1.5% 4 +[I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.3.2 549 7 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,T768I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.3.2 549 7 1.3% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.10 548 348 63.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.10 548 104 19.0% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.10 548 24 4.4% 2 +[W64R,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.10 548 10 1.8% 3 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T678-,+679K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,N679K] CH.1.1.10 548 4 0.7% 4 +[W64R,K147E,W152R,F157L,I210V,V213G,+255L,G257-,K444T,L452R,F486S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.52 545 363 66.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1141W]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.52 545 78 14.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1141W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.52 545 10 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A684S,D950N,L1141W]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.52 545 7 1.3% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,L1141W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.52 545 6 1.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1141W,K1181N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4 544 403 74.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.4 544 24 4.4% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4 544 7 1.3% 1 +[D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4 544 7 1.3% 1 +[Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4 544 6 1.1% 1 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.6 544 446 82.0% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] (consensus) P.1.6 544 25 4.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.6 544 15 2.8% 1 +[L5F,L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.6 544 13 2.4% 1 +[L18F,T20N,P26S,A27T,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.6 544 9 1.7% 4 +[L18F,T20N,P26S,D138Y,L141F,G142-,V143-,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] FY.3 544 370 68.0% 0 +[Y200C] (consensus) FY.3 544 11 2.0% 1 +[Y200C,R408N]-[R408S] FY.3 544 8 1.5% 1 +[Y200C,A222V] FY.3 544 6 1.1% 1 +[H146K,Y200C]-[H146Q] FY.3 544 5 0.9% 1 +[Y200C]-[R408S] DJ.1.1 543 299 55.1% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) DJ.1.1 543 73 13.4% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DJ.1.1 543 55 10.1% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DJ.1.1 543 49 9.0% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DJ.1.1 543 4 0.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] B.1.351.3 542 210 38.7% 0 +[L18F,A67V,D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.3 542 209 38.6% 1 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.351.3 542 9 1.7% 4 +[L18F,D80A,D215G,L242-,A243-,L244-,R246-,S247-,Y248-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.3 542 7 1.3% 4 +[L18F,D80A,D215G,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.3 542 6 1.1% 2 +[L18F,D80A,D138N,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.16 540 516 95.6% 0 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.16 540 4 0.7% 1 +[S112P,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.16 540 3 0.6% 1 +[N439K,I472V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.16 540 2 0.4% 1 +[N439K,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.16 540 1 0.2% 1 +[N439K,A623S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466 538 210 39.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.466 538 71 13.2% 1 +[S12F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466 538 11 2.0% 2 +[S12F,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466 538 9 1.7% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466 538 8 1.5% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3.1 538 498 92.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.3.1 538 16 3.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3.1 538 10 1.9% 1 +[V615I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3.1 538 2 0.4% 1 +[E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3.1 538 1 0.2% 1 +[S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.1 538 509 94.6% 0 +[M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) L.1 538 7 1.3% 1 +[A262S,M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.1 538 5 0.9% 1 +[I1132V,M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.1 538 2 0.4% 1 +[P681L,M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.1 538 1 0.2% 1 +[P579S,M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CA.7 537 408 76.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CA.7 537 25 4.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,Q613H,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.7 537 10 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,T747I,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.7 537 7 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] CA.7 537 5 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,P621S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.36.38 535 379 70.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.38 535 77 14.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.38 535 16 3.0% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.38 535 11 2.1% 1 +[P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.38 535 5 0.9% 1 +[V1065A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.86 533 228 42.8% 0 (consensus) XBB.1.5.86 533 33 6.2% 1 +[T883I] XBB.1.5.86 533 25 4.7% 1 -[R346T] XBB.1.5.86 533 24 4.5% 2 -[R346T,K417N] XBB.1.5.86 533 21 3.9% 1 +[T676I] BW.1 531 266 50.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BW.1 531 114 21.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1 531 33 6.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,N703I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1 531 26 4.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BW.1 531 6 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,N641S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BN.1.3.12 531 425 80.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.12 531 23 4.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.3.12 531 6 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.12 531 6 1.1% 1 +[K147E,W152R,F157L,N164S,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.12 531 5 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S940F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] CH.1.1.19 529 368 69.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.19 529 43 8.1% 1 +[V6F,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.19 529 21 4.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.19 529 14 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,G1219C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.19 529 9 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FR.1 529 382 72.2% 0 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) FR.1 529 16 3.0% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P] FR.1 529 12 2.3% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1 529 9 1.7% 4 +[K187E,I210V,V213G,G257S,K356T]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1 529 8 1.5% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,L1234F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.177.69 528 433 82.0% 0 +[A222V,S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.69 528 15 2.8% 1 +[A222V,G769V,S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.69 528 13 2.5% 1 +[A222V,A344S,S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.69 528 11 2.1% 1 +[A222V,T385I,S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.69 528 10 1.9% 1 +[A222V,S640F,S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.17 525 393 74.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.17 525 20 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1139N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.17 525 10 1.9% 1 +[H49Y,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.17 525 9 1.7% 1 +[H69-,V70-,V213G,G261V,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.17 525 8 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.16.18 525 289 55.0% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.18 525 43 8.2% 1 +[E180V,G261V,T478R]-[T478K] XBB.1.16.18 525 17 3.2% 1 +[E180V,T478R,Q675H]-[T478K] XBB.1.16.18 525 16 3.0% 1 +[E180V,T478R,D1153Y]-[T478K] XBB.1.16.18 525 11 2.1% 1 +[E180V,T478R]-[K417N,T478K] B.1.127 524 491 93.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.127 524 15 2.9% 1 +[H146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.127 524 2 0.4% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.127 524 2 0.4% 1 +[F59S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.127 524 2 0.4% 1 +[T778I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.1 524 168 32.1% 0 +[A701V] (consensus) FL.1 524 93 17.7% 1 +[A701V,Q1208H] FL.1 524 69 13.2% 2 +[T478R,P521T,A701V]-[T478K] FL.1 524 27 5.2% 1 +[L5F,A701V] FL.1 524 12 2.3% 1 +[T478R,A701V]-[T478K] BA.5.5.3 524 327 62.4% 0 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.5.3 524 52 9.9% 1 +[H69-,V70-,T76I,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.3 524 34 6.5% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.3 524 16 3.1% 1 +[H69-,V70-,T76I,K147E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.3 524 11 2.1% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.119.1 523 197 37.7% 0 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,I834T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.119.1 523 152 29.1% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,I834T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119.1 523 21 4.0% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,I834T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119.1 523 19 3.6% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,I834T,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119.1 523 12 2.3% 2 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,I834T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.9 523 421 80.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,S704L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.9 523 15 2.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,S704L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.9 523 13 2.5% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,S704L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.9 523 5 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,S704L,A831V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.9 523 4 0.8% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,S704L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BF.7.14.4 523 428 81.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14.4 523 6 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.4 523 4 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T572I,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.4 523 4 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1083R,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.4 523 3 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A871V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.416.1 522 403 77.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.416.1 522 31 5.9% 1 +[R408K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.416.1 522 12 2.3% 2 +[D138Y,D1184G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.416.1 522 10 1.9% 1 +[K854N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.416.1 522 9 1.7% 1 +[T1231I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.30 522 374 71.6% 0 +[A348T] (consensus) XBB.1.5.30 522 20 3.8% 1 +[H146K,A348T]-[H146Q] XBB.1.5.30 522 19 3.6% 1 +[A348T]-[K417N] XBB.1.5.30 522 8 1.5% 1 +[L5F,A348T] XBB.1.5.30 522 8 1.5% 1 +[A348T,P1263L] HF.1.1 521 414 79.5% 0 +[E180V,K304N,T478R,D1084N,H1101Y]-[T478K] (consensus) HF.1.1 521 14 2.7% 2 +[E180V,K304N,T478R,H1101Y,D1163Y]-[T478K] HF.1.1 521 12 2.3% 1 +[E180V,K304N,T478R,H1101Y]-[T478K] HF.1.1 521 7 1.3% 1 +[H146K,E180V,K304N,T478R,D1084N,H1101Y]-[H146Q,T478K] HF.1.1 521 4 0.8% 1 +[E180V,K304N,T478R,D1084N,H1101Y]-[R408S,T478K] B.1.404 520 414 79.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.404 520 14 2.7% 1 +[V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.404 520 9 1.7% 1 +[G1251R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.404 520 6 1.2% 1 +[T76S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.404 520 5 1.0% 1 +[T286I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.64 520 358 68.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.64 520 49 9.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.64 520 34 6.5% 1 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.64 520 7 1.3% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.64 520 6 1.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.9.2.1 520 422 81.2% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.9.2.1 520 37 7.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,R1091L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.1 520 17 3.3% 1 +[T19R,E156G,F157-,R158-,A222V,K444T,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.1 520 15 2.9% 2 +[T19R,E156G,F157-,R158-,A222V,S373L,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.1 520 11 2.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q474H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.26 520 304 58.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.26 520 21 4.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Y1155H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.26 520 16 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.26 520 15 2.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.26 520 15 2.9% 2 +[A67S,H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.5 520 463 89.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.11.5 520 4 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1246S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.5 520 3 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.5 520 3 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S640F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.5 520 3 0.6% 1 +[H69-,V70-,V213G,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] FL.16 520 313 60.2% 0 +[D215V] (consensus) FL.16 520 60 11.5% 1 +[D215V,F456L] FL.16 520 11 2.1% 1 +[H146K,D215V]-[H146Q] FL.16 520 10 1.9% 1 +[L5F,D215V] FL.16 520 8 1.5% 2 +[D215V,F456L,G1219V] B.1.564.1 518 392 75.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.564.1 518 32 6.2% 1 +[T76I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564.1 518 20 3.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564.1 518 11 2.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564.1 518 11 2.1% 1 +[A344S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.25 517 399 77.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.25 517 6 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,A829T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.25 517 5 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,R408N,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] CH.1.1.25 517 5 1.0% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,A829T,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.25 517 4 0.8% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.486 517 413 79.9% 0 +[T29I,T572I,Q677H,D936N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.486 517 15 2.9% 1 +[T29I,T572I,Q677H,A684V,D936N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.486 517 6 1.2% 2 +[T29I,M153V,T572I,T573I,Q677H,D936N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.486 517 5 1.0% 1 +[T29I,E484K,T572I,Q677H,D936N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.486 517 5 1.0% 1 +[T29I,T572I,T573I,Q677H,D936N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.16 517 393 76.0% 0 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.16 517 27 5.2% 1 +[L5F,H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.16 517 22 4.3% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.16 517 10 1.9% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.16 517 9 1.7% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.15 516 383 74.2% 0 +[H69-,V70-,V213G,Y248H,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.15 516 25 4.8% 2 +[H69-,V70-,V213G,Y248H,T250I,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.15 516 13 2.5% 1 +[L5F,H69-,V70-,V213G,Y248H,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.15 516 11 2.1% 1 +[H69-,V70-,V213G,Y248H,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.15 516 9 1.7% 1 +[H69-,V70-,V213G,Y248H,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.8 515 373 72.4% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,P809S,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.8 515 22 4.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,A222V,G339D,S371L,Q493R,G496S,T547K,P809S,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.8 515 21 4.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,P809S,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.8 515 16 3.1% 2 +[A67V,H69-,V70-,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,P809S,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S,Y505H] BA.1.8 515 6 1.2% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,P809S,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.4.1.9 514 284 55.3% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.9 514 39 7.6% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.9 514 37 7.2% 1 +[V3G,H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.9 514 14 2.7% 1 +[V3G,H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.9 514 13 2.5% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,C1236F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.5 514 469 91.2% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,A831V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.5 514 5 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,A831V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.5 514 4 0.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,A831V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.5 514 4 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,A831V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.5 514 2 0.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,A831V,N856K,L981F,V1230L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] EF.2 513 417 81.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EF.2 513 12 2.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,N603D]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.2 513 11 2.1% 1 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.2 513 9 1.8% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.2 513 8 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FL.14 512 322 62.9% 0 +[V1122M] (consensus) FL.14 512 23 4.5% 1 +[T76I,V1122M] FL.14 512 20 3.9% 1 +[G482S,V1122M] FL.14 512 19 3.7% 1 +[W152R,V1122M] FL.14 512 12 2.3% 1 +[Q14H,V1122M] BA.1.14.2 511 384 75.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.14.2 511 25 4.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.14.2 511 18 3.5% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.14.2 511 11 2.2% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.14.2 511 7 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,H625R,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.177.43 511 396 77.5% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.43 511 23 4.5% 1 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.43 511 21 4.1% 1 +[A222V,L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.43 511 16 3.1% 1 +[A222V,S1030A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.43 511 4 0.8% 2 +[A222V,I896T,S1030A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.1.1 511 364 71.2% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.1.1 511 40 7.8% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,N764K] BN.1.1.1 511 18 3.5% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.1.1 511 5 1.0% 1 +[R21T,K147E,W152R,F157L,N185D,I210V,V213G,G257S,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.1.1 511 3 0.6% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P] BQ.1.1.46 511 351 68.7% 0 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.46 511 19 3.7% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.46 511 13 2.5% 2 +[H69-,V70-,F157L,V213G,T240I,G339D,K444T,L452R,F486V,T547I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.46 511 10 2.0% 2 +[H69-,V70-,F157L,V213G,G339D,P426S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.46 511 9 1.8% 1 +[H69-,V70-,F157L,K182I,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.46 510 232 45.5% 0 +[V143F,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.46 510 148 29.0% 3 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.46 510 26 5.1% 1 +[V143F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.46 510 21 4.1% 1 +[V143F,L179F,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.46 510 5 1.0% 2 +[V143F,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XBB.1.16.8 510 212 41.6% 0 +[E180V,T478R,T732I]-[T478K] (consensus) XBB.1.16.8 510 78 15.3% 1 +[E180V,D198G,T478R,T732I]-[T478K] XBB.1.16.8 510 77 15.1% 1 +[E180V,T323I,T478R,T732I]-[T478K] XBB.1.16.8 510 20 3.9% 2 +[E180V,D198G,T478R,T732I,Q1208H]-[T478K] XBB.1.16.8 510 15 2.9% 1 +[E180V,N185D,T478R,T732I]-[T478K] AY.4.14 508 457 90.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.14 508 13 2.6% 3 +[T19R,T95I,E156G,F157-,R158-,I231M,G339D,E340K,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.14 508 11 2.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.14 508 6 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,V382L,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.14 508 6 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,A684V,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.31 508 380 74.8% 0 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.31 508 23 4.5% 1 +[T29I,H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.31 508 6 1.2% 1 +[H69-,V70-,K147E,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.31 508 6 1.2% 1 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V,K529N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.31 508 5 1.0% 2 +[H49Y,H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CH.1.1.7 508 363 71.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.7 508 43 8.5% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.7 508 10 2.0% 6 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,K444T,L452R,F486S,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.7 508 6 1.2% 1 +[K147E,W152R,F157L,L176F,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.7 508 5 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.39.1.3 507 294 58.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.1.3 507 162 32.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.3 507 8 1.6% 1 +[T19R,T76I,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.3 507 4 0.8% 1 +[T19R,T95I,E156G,F157-,R158-,E340K,L452R,P681R,D950N,P1162A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.3 507 3 0.6% 1 +[T19R,R21K,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.14 507 382 75.3% 0 +[W64L,H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.14 507 32 6.3% 1 +[W64L,H69-,V70-,V213G,G339D,K444M,L452R,F486V,V1104L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.14 507 9 1.8% 1 +[W64L,H69-,V70-,V213G,G339D,K444M,L452R,F486V,S943N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.14 507 7 1.4% 1 +[W64L,H69-,V70-,G181V,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.14 507 5 1.0% 1 +[W64L,H69-,V70-,V213G,G339D,K444M,L452R,F486V,D1146Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CR.1 507 248 48.9% 0 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CR.1 507 86 17.0% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1 507 11 2.2% 1 +[L5F,H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1 507 10 2.0% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V,S967G]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1 507 9 1.8% 10 +[G339D,K444R,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.3 507 307 60.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.11.3 507 64 12.6% 2 +[A27-,H69-,V70-,V213G,G339D,L452R,F486V]-[L24-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.3 507 27 5.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.3 507 24 4.7% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.3 507 6 1.2% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,N764R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,N764K] BA.2.81 507 252 49.7% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.81 507 135 26.6% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.81 507 15 3.0% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.81 507 13 2.6% 1 +[V213G,T250I,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.81 507 13 2.6% 2 +[V213G,T250I,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.9 506 412 81.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.9 506 9 1.8% 2 +[H69-,V70-,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.9 506 8 1.6% 1 +[V213G,G339D,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.9 506 7 1.4% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.9 506 7 1.4% 1 +[V213G,G339D,Q493R,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.65 506 380 75.1% 0 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.65 506 40 7.9% 1 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V,T572S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.65 506 11 2.2% 1 +[H69-,V70-,K147I,G181V,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.65 506 6 1.2% 1 +[H69-,V70-,K147I,E180D,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.65 506 3 0.6% 2 +[H69-,V70-,K147I,V213G,G339D,K444M,L452R,F486V,T572S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.416 505 304 60.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.416 505 69 13.7% 1 +[V382L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.416 505 28 5.5% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.416 505 6 1.2% 1 +[L821V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.416 505 5 1.0% 1 +[S359R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.32 505 431 85.3% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.32 505 6 1.2% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,P812S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.32 505 5 1.0% 1 +[H69-,V70-,D80Y,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.32 505 4 0.8% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,R765L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.32 505 4 0.8% 2 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.11 503 479 95.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.11 503 4 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,T478E,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BA.5.1.11 503 3 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.11 503 3 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,K947E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.11 503 3 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.36.31 502 263 52.4% 0 +[R102S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.31 502 32 6.4% 1 +[R102S,A222V,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.31 502 27 5.4% 1 +[R102S,A222V]-[L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.31 502 18 3.6% 2 +[R102S,A222V,Q677H,M1050I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.31 502 13 2.6% 1 +[R102S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.51 502 301 60.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.51 502 164 32.7% 1 +[I1225F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.51 502 8 1.6% 2 +[N1074D,I1225F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.51 502 7 1.4% 1 +[I100L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.51 502 5 1.0% 1 +[A348S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.30 501 455 90.8% 0 +[S255F,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.30 501 8 1.6% 2 +[R102I,S255F,T573I,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.30 501 5 1.0% 1 +[D138H,S255F,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.30 501 4 0.8% 1 +[L5F,S255F,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.30 501 3 0.6% 1 +[S255F,T859I,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.10 500 374 74.8% 0 +[Y145H,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.10 500 12 2.4% 1 +[Y145H,K147E,W152R,F157L,N185D,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.10 500 11 2.2% 1 +[Y145H,K147E,W152R,F157L,I210V,V213G,G257S,K356T,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.10 500 10 2.0% 1 +[Y145H,K147E,W152R,F157L,I210V,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F486P] BN.1.10 500 8 1.6% 1 +[Y145H,K147E,W152R,F157L,I210V,V213G,G257S,K356T,F565L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.1.288 500 452 90.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.288 500 14 2.8% 1 +[E1207D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.288 500 8 1.6% 1 -[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.288 500 3 0.6% 1 +[D88Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.288 500 2 0.4% 1 +[L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.3 498 459 92.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.3 498 12 2.4% 1 +[N856T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.3 498 2 0.4% 1 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.3 498 2 0.4% 1 +[S1170F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.3 498 2 0.4% 2 +[N856T,A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DB.1 498 215 43.2% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DB.1 498 158 31.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DB.1 498 26 5.2% 1 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DB.1 498 19 3.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S691P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DB.1 498 13 2.6% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704T]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.3 498 242 48.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EE.3 498 59 11.8% 1 +[H69-,V70-,V213G,L216F,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.3 498 42 8.4% 1 +[H69-,V70-,E156Q,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.3 498 23 4.6% 2 +[H69-,V70-,E156Q,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.3 498 22 4.4% 2 +[H69-,V70-,V213G,L216F,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] GK.3.1 496 408 82.3% 0 +[L455F,F456L,A475V] (consensus) GK.3.1 496 29 5.8% 1 +[L455F,F456L,A475V,P809S] GK.3.1 496 5 1.0% 1 +[L455F,F456L,A475V,V1264L] GK.3.1 496 4 0.8% 1 +[H146K,L455F,F456L,A475V]-[H146Q] GK.3.1 496 3 0.6% 1 +[L455F,F456L,A475V]-[Y144-] N.5 495 121 24.4% 0 +[Q414R,T778I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.5 495 65 13.1% 1 +[G257S,Q414R,T778I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.5 495 59 11.9% 1 +[Q414R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.5 495 54 10.9% 2 +[H49Y,Q414R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.5 495 21 4.2% 2 +[M153T,Q414R,T778I,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.326 494 329 66.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.326 494 8 1.6% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.326 494 7 1.4% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.326 494 6 1.2% 1 +[L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.326 494 5 1.0% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.36 493 251 50.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.36 493 47 9.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,D574N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.36 493 28 5.7% 3 +[H69-,V70-,N148S,K150E,V213G,N334K,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.36 493 19 3.9% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A522P,I1130M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.36 493 11 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FL.20 488 337 69.1% 0 +[Q52H,F456L] (consensus) FL.20 488 18 3.7% 1 +[Q52H,F456L,T478R]-[T478K] FL.20 488 14 2.9% 1 +[Q52H,F456L,A688V] FL.20 488 9 1.8% 1 +[Q52H,K356T,F456L] FL.20 488 6 1.2% 1 +[Q52H,H146K,F456L]-[H146Q] B.1.36.16 488 225 46.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.16 488 88 18.0% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.16 488 66 13.5% 1 +[S459F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.16 488 17 3.5% 2 +[L5F,S459F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.16 488 15 3.1% 1 +[A163V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.28 487 276 56.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.28 487 65 13.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.28 487 21 4.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.28 487 8 1.6% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.28 487 8 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BT.2 487 399 81.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BT.2 487 10 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BT.2 487 7 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BT.2 487 7 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BT.2 487 6 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1117I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.4.3 486 350 72.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.4.3 486 16 3.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.4.3 486 9 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N481K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.3 486 8 1.6% 1 +[K147E,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.3 486 6 1.2% 1 +[I68T,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.2.73 486 431 88.7% 0 +[V213G,G257S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.73 486 12 2.5% 1 +[L176F,V213G,G257S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.73 486 5 1.0% 1 +[V213G,G257S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.73 486 5 1.0% 1 +[V213G,G257S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.73 486 2 0.4% 1 +[V213G,G257S,G339D,Q493R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.57 484 398 82.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.57 484 14 2.9% 1 +[V213G,Q218E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.57 484 9 1.9% 1 +[V213G,Y248-,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.57 484 6 1.2% 1 +[V213G,G339D,Q493R,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.57 484 5 1.0% 1 +[V213G,G339D,Q493R,D1260H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.61 481 355 73.8% 0 (consensus) XBB.1.5.61 481 19 4.0% 1 +[Q675H] XBB.1.5.61 481 18 3.7% 1 -[K417N] XBB.1.5.61 481 13 2.7% 2 +[Q675H,Y1272H] XBB.1.5.61 481 7 1.5% 2 +[Q675R,G1099D] AY.60 481 213 44.3% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.60 481 141 29.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.60 481 21 4.4% 1 +[T19R,E156G,F157-,R158-,A222V,V289L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.60 481 20 4.2% 1 +[T19R,G72W,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.60 481 16 3.3% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GB.1 480 310 64.6% 0 +[L518V] (consensus) GB.1 480 21 4.4% 1 +[S254F,L518V] GB.1 480 11 2.3% 1 +[L518V,G1219C] GB.1 480 9 1.9% 1 +[L518V,E554V] GB.1 480 8 1.7% 2 +[H146K,T323I,L518V]-[H146Q] AZ.3 480 374 77.9% 0 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AZ.3 480 51 10.6% 1 +[T95I,A222V,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.3 480 13 2.7% 1 +[H49Y,T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.3 480 12 2.5% 1 +[T95I,M177I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.3 480 4 0.8% 1 +[T95I,E484K,D796H,A871S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.128 478 287 60.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.128 478 35 7.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.128 478 35 7.3% 1 +[T19R,T95I,E156G,F157-,R158-,T250A,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.128 478 11 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,A653V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.128 478 9 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,R214H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EL.1 478 228 47.7% 0 +[Q675H] (consensus) EL.1 478 39 8.2% 1 +[P521S,Q675H] EL.1 478 29 6.1% 1 +[Q675H]-[K417N] EL.1 478 16 3.3% 1 +[H146K,Q675H]-[H146Q] EL.1 478 8 1.7% 1 +[D178H,Q675H] DN.1.1 477 369 77.4% 0 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.1.1 477 21 4.4% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1.1 477 11 2.3% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,I1216T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1.1 477 9 1.9% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1.1 477 9 1.9% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,K1045T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.1.3 477 444 93.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.3 477 4 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G219D,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.3 477 4 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,I326V,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.3 477 3 0.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,Q1142R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.3 477 2 0.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,D936Y,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.2.16 475 441 92.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.16 475 6 1.3% 1 +[V213G,G339D,Q493R,E1195Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.16 475 4 0.8% 1 +[V213G,G339D,Q493R,S691P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.16 475 3 0.6% 2 +[N211-,L212I,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.16 475 3 0.6% 1 +[V213G,G339D,Q493R,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.4.4 474 131 27.6% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.4.4 474 95 20.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.4.4 474 42 8.9% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.4.4 474 20 4.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.4.4 474 11 2.3% 2 +[+16MPLF,R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] FR.2 474 390 82.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) FR.2 474 13 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,G594S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.2 474 12 2.5% 3 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S680-,+681H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,P681H] FR.2 474 5 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A1078S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.2 474 4 0.8% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q1113H,I1114F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBB.1.5.91 474 263 55.5% 0 +[P621S] (consensus) XBB.1.5.91 474 86 18.1% 2 +[T29I,P621S,A1078S] XBB.1.5.91 474 49 10.3% 1 +[T29I,P621S] XBB.1.5.91 474 7 1.5% 1 +[P621S,Q677H] XBB.1.5.91 474 5 1.1% 2 +[T29I,H66R,P621S] BQ.1.1.78 474 414 87.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.78 474 6 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.78 474 6 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.78 474 5 1.1% 1 +[V36F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.78 474 4 0.8% 1 +[H69-,V70-,V213G,L216I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.16.21 473 274 57.9% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.21 473 34 7.2% 1 +[N30S,E180V,T478R]-[T478K] XBB.1.16.21 473 15 3.2% 1 +[E180V,T478R,N556K]-[T478K] XBB.1.16.21 473 14 3.0% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.21 473 10 2.1% 1 +[E180V,T478R]-[Y144-,T478K] AY.132 473 422 89.2% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.132 473 25 5.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1079T]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.132 473 2 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,V622A,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.132 473 2 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,Q1113E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.132 473 2 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1233I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.16.23 471 284 60.3% 0 +[E180V,K304Q,T478R]-[T478K] (consensus) XBB.1.16.23 471 27 5.7% 1 +[N148T,E180V,K304Q,T478R]-[T478K] XBB.1.16.23 471 21 4.5% 1 +[E180V,K304Q,T478R,A575S]-[T478K] XBB.1.16.23 471 9 1.9% 1 +[H146K,E180V,K304Q,T478R]-[H146Q,T478K] XBB.1.16.23 471 9 1.9% 1 +[E180V,K304Q,T478R,T961S]-[T478K] B.1.474 470 354 75.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] (consensus) B.1.474 470 35 7.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] B.1.474 470 12 2.6% 2 +[L5F,P793L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] B.1.474 470 10 2.1% 2 +[L5F,Q314K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] B.1.474 470 9 1.9% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] GN.1.1 470 321 68.3% 0 +[F456L] (consensus) GN.1.1 470 34 7.2% 1 +[F456L,L858I] GN.1.1 470 11 2.3% 1 +[H146K,F456L]-[H146Q] GN.1.1 470 8 1.7% 1 +[M177T,F456L] GN.1.1 470 8 1.7% 3 +[M177I,F456L,A522S,L858I] EN.1 469 374 79.7% 0 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EN.1 469 13 2.8% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EN.1 469 8 1.7% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,S1242N,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EN.1 469 3 0.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,S640F,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EN.1 469 3 0.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,S939F,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.236 469 249 53.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.236 469 49 10.4% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.236 469 23 4.9% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.236 469 14 3.0% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.236 469 8 1.7% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.52 469 338 72.1% 0 +[A222V,P1162R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.52 469 26 5.5% 1 +[R102I,A222V,P1162R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.52 469 15 3.2% 1 +[E96Q,A222V,P1162R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.52 469 14 3.0% 1 +[A222V,P1162R,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.52 469 9 1.9% 2 +[L5F,A222V,A264S,P1162R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.19 469 352 75.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.19 469 31 6.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.19 469 6 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,V1094A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.19 469 6 1.3% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E654Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.19 469 5 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,R567K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DF.1.1 469 414 88.3% 0 +[H69-,V70-,V213G,A262S,G339D,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DF.1.1 469 5 1.1% 1 +[H69-,V70-,V213G,A262S,G339D,V445A,L452R,F486V,V622I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DF.1.1 469 4 0.9% 1 +[H69-,V70-,V213G,A262S,G339N,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DF.1.1 469 4 0.9% 1 +[H69-,V70-,G184S,V213G,A262S,G339D,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DF.1.1 469 3 0.6% 1 +[H69-,V70-,V213G,A262S,G339D,V445A,L452R,F486V,P812S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] FY.3.3 469 361 77.0% 0 +[Y200C] (consensus) FY.3.3 469 8 1.7% 1 +[Y200C,S939F] FY.3.3 469 8 1.7% 1 +[F157L,Y200C] FY.3.3 469 6 1.3% 1 +[Y200C,Y248H] FY.3.3 469 5 1.1% 1 +[H146K,Y200C]-[H146Q] XBB.3 469 221 47.1% 0 +[F486S]-[G252V,F486P] (consensus) XBB.3 469 75 16.0% 1 +[F486S]-[T19I,G252V,F486P] XBB.3 469 11 2.3% 1 +[T323I,F486S]-[G252V,F486P] XBB.3 469 9 1.9% 5 +[F486S]-[L24-,P25-,P26-,A27S,Y144-,G252V,F486P] XBB.3 469 9 1.9% 1 +[F486S]-[G252V,K417N,F486P] FL.1.5 468 254 54.3% 0 +[F456L,A701V] (consensus) FL.1.5 468 25 5.3% 1 +[I68T,F456L,A701V] FL.1.5 468 18 3.8% 1 +[N164H,F456L,A701V] FL.1.5 468 9 1.9% 3 +[F456L,N481K,F490P,P681R,A701V]-[F490S,P681H] FL.1.5 468 8 1.7% 1 +[N188S,F456L,A701V] AY.33.1 467 441 94.4% 0 +[T19R,T29A,H49Y,E156G,F157-,R158-,T250I,T299I,L452R,Q613H,E654K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.33.1 467 4 0.9% 1 +[T19R,T29A,H49Y,V62L,E156G,F157-,R158-,T250I,T299I,L452R,Q613H,E654K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33.1 467 4 0.9% 1 +[T19R,T29A,H49Y,E156G,F157-,R158-,T250I,T299I,L452R,Q613H,E654K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33.1 467 3 0.6% 1 +[T19R,T29A,H49Y,E156G,F157-,R158-,T250I,T299I,L452R,Q613H,E654K,P681R,D950N,G1246S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33.1 467 2 0.4% 1 +[T19R,T29A,H49Y,E156G,F157-,R158-,T250I,T299I,L452R,Q613H,E654K,S680Y,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.71 467 326 69.8% 0 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.71 467 90 19.3% 1 +[W64R,G75V,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.71 467 7 1.5% 1 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.71 467 3 0.6% 1 +[W64R,K150N,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.71 467 2 0.4% 1 +[W64R,K147E,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] HT.2 467 303 64.9% 0 +[T51I] (consensus) HT.2 467 13 2.8% 1 +[T51I]-[K417N] HT.2 467 13 2.8% 2 +[T51I,G261S,T478R]-[T478K] HT.2 467 11 2.4% 1 +[T51I,A1070S] HT.2 467 10 2.1% 1 +[T51I,M1229I] B.1.1.312 466 386 82.8% 0 +[Q957L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.312 466 11 2.4% 1 +[A262S,Q957L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.312 466 9 1.9% 1 +[A688V,Q957L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.312 466 6 1.3% 1 +[L5F,Q957L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.312 466 6 1.3% 1 +[A67V,Q957L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.9.4 466 315 67.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.4 466 65 13.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.9.4 466 8 1.7% 1 +[V213G,G339D,Q493R,D1259H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.4 466 8 1.7% 1 +[V213G,G339D,Q493R,A845S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.4 466 5 1.1% 1 +[V213G,G339D,Q493R,C1243S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BR.1 465 331 71.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BR.1 465 30 6.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,Y489H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.1 465 14 3.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,E1150K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.1 465 13 2.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.1 465 13 2.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,V687A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] CK.3 464 208 44.8% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.3 464 104 22.4% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.3 464 25 5.4% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.3 464 14 3.0% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.3 464 12 2.6% 3 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,R1014T,I1114V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] AL.1 464 427 92.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AL.1 464 8 1.7% 1 +[A684V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AL.1 464 4 0.9% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AL.1 464 2 0.4% 4 +[L141-,G142-,V143-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AL.1 464 2 0.4% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KP.3 463 380 82.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KP.3 463 21 4.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KP.3 463 11 2.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KP.3 463 3 0.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KP.3 463 3 0.6% 1 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDP 463 258 55.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDP 463 52 11.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDP 463 28 6.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDP 463 16 3.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDP 463 8 1.7% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBB.1.5.76 463 266 57.5% 0 (consensus) XBB.1.5.76 463 40 8.6% 1 -[R408S] XBB.1.5.76 463 16 3.5% 1 -[K417N] XBB.1.5.76 463 16 3.5% 1 +[G1219C] XBB.1.5.76 463 13 2.8% 1 +[H146K]-[H146Q] B.1.1.302 462 404 87.4% 0 +[V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.302 462 11 2.4% 1 +[G261R,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.302 462 6 1.3% 1 +[L585F,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.302 462 5 1.1% 1 +[S12C,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.302 462 4 0.9% 1 +[T1076I,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.34 462 292 63.2% 0 (consensus) XBB.1.5.34 462 30 6.5% 1 +[C1253F] XBB.1.5.34 462 12 2.6% 1 +[A623V] XBB.1.5.34 462 11 2.4% 1 +[T323I] XBB.1.5.34 462 9 1.9% 1 +[H146K]-[H146Q] BQ.1.1.72 460 360 78.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.72 460 12 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.72 460 12 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.72 460 8 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.72 460 4 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S689I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.50 460 389 84.6% 0 +[P621S] (consensus) XBB.1.5.50 460 12 2.6% 1 +[T323I,P621S] XBB.1.5.50 460 9 2.0% 1 +[G75V,P621S] XBB.1.5.50 460 6 1.3% 1 +[T572I,P621S] XBB.1.5.50 460 5 1.1% 3 +[N370-,+371F,P621S]-[S371F] FL.27 457 329 72.0% 0 (consensus) FL.27 457 11 2.4% 4 +[S256L,S494P,N616D]-[T19I] FL.27 457 11 2.4% 1 +[D389G] FL.27 457 10 2.2% 1 +[L5F] FL.27 457 7 1.5% 1 +[Q613H] BQ.1.21 457 347 75.9% 0 +[H69-,V70-,V213G,G339D,R346S,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.21 457 12 2.6% 1 +[H69-,V70-,V83L,V213G,G339D,R346S,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.21 457 9 2.0% 1 +[H69-,V70-,V213G,G339D,R346S,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.21 457 8 1.8% 1 +[H69-,V70-,V213G,G339D,R346S,K444T,L452R,F486V,F888L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.21 457 5 1.1% 1 +[H69-,V70-,V213G,G339D,R346S,K444T,L452R,F486V,A701V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.1.263 454 286 63.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.263 454 31 6.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.263 454 24 5.3% 2 +[L452M,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.263 454 10 2.2% 1 +[T19A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.263 454 8 1.8% 2 +[S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.1.1.8 453 355 78.4% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.8 453 36 7.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,I931V,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.8 453 5 1.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,P1079T]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.8 453 4 0.9% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.8 453 3 0.7% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,E154Q,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,I931V,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] HY.1 453 148 32.7% 0 +[T478R,P793S,V1122M]-[T478K] HY.1 453 67 14.8% 1 +[T478R,V1122M]-[T478K] (consensus) HY.1 453 65 14.3% 3 +[F456L,T478R,T618S,V1122M]-[T478K] HY.1 453 25 5.5% 2 +[F456L,T478R,V1122M]-[T478K] HY.1 453 11 2.4% 1 +[T478R,P793S,V1122M]-[K417N,T478K] B.1.1.232 451 374 82.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.232 451 7 1.6% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.232 451 7 1.6% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.232 451 5 1.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.232 451 5 1.1% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.63 451 334 74.1% 0 +[H69-,V70-,V213G,Y248H,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.63 451 10 2.2% 1 +[H69-,V70-,V213G,Y248H,G339D,K444T,L452R,E484V,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,E484A,F486P,F490S] BQ.1.1.63 451 8 1.8% 1 +[H69-,V70-,V213G,Y248H,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.63 451 8 1.8% 1 +[H69-,V70-,V213G,Y248H,G339D,K444T,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.63 451 7 1.6% 1 +[H69-,V70-,V213G,Y248H,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.62 450 378 84.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.62 450 13 2.9% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.62 450 8 1.8% 1 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.62 450 7 1.6% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.62 450 6 1.3% 1 +[G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.27 450 325 72.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.27 450 49 10.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.27 450 8 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.27 450 5 1.1% 1 +[H69-,V70-,V213G,I231T,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.27 450 5 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D950A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.61 450 386 85.8% 0 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.61 450 15 3.3% 1 +[W64R,V213G,G339D,Q493R,R683W]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.61 450 13 2.9% 1 +[W64R,L176F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.61 450 8 1.8% 1 +[L5F,W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.61 450 2 0.4% 1 +[W64R,V213G,G339D,Q493R,A684V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CM.12 450 340 75.6% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.12 450 22 4.9% 2 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,V1060I,C1250Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.12 450 17 3.8% 1 +[L5F,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.12 450 11 2.4% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,D1260Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.12 450 7 1.6% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,S708A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] AY.24.1 449 260 57.9% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.24.1 449 73 16.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24.1 449 33 7.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q677H,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24.1 449 19 4.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,V483A,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24.1 449 15 3.3% 1 +[T19R,E156G,F157-,R158-,A222V,Y265C,L452R,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.2 449 379 84.4% 0 +[N439K,P681R,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AU.2 449 10 2.2% 1 +[N439K,P681R,L1224F,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.2 449 8 1.8% 1 +[E180D,N439K,P681R,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.2 449 7 1.6% 1 +[G339S,N439K,P681R,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.2 449 5 1.1% 2 +[I68-,N439K,P681R,V1228L,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.1.5 446 342 76.7% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.5 446 18 4.0% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.1.5 446 8 1.8% 1 +[V3G,H69-,V70-,V213G,S247N,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.5 446 6 1.3% 1 +[V3G,H69-,V70-,V213G,G339D,R346K,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.5 446 5 1.1% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,S940F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.33.2 445 137 30.8% 0 +[T19R,T29A,E156G,F157-,R158-,T250I,R346K,L452R,P681R,P812L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33.2 445 96 21.6% 2 +[T19R,T29A,E156G,F157-,R158-,T250I,R346K,L452R,V503F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33.2 445 94 21.1% 1 +[T19R,T29A,E156G,F157-,R158-,T250I,R346K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.33.2 445 28 6.3% 2 +[T19R,T29A,E156G,F157-,R158-,T250I,R346K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33.2 445 14 3.1% 3 +[T19R,T29A,E156G,F157-,R158-,T250I,R346K,L452R,V503F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.6 445 322 72.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.6 445 26 5.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T732I,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.6 445 9 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,R408G,K444T,L452R,F486S,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] CH.1.1.6 445 9 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T618S,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.6 445 8 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T732I,A831V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.5.1.19 445 333 74.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.19 445 11 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.19 445 9 2.0% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.19 445 8 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.19 445 7 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1146H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EG.5.1.2 443 101 22.8% 0 +[Q52H,R158G,F456L] EG.5.1.2 443 69 15.6% 1 +[Q52H,F456L] (consensus) EG.5.1.2 443 63 14.2% 2 +[Q52H,F456L,V687L] EG.5.1.2 443 28 6.3% 2 +[Q52H,T76A,F456L] EG.5.1.2 443 24 5.4% 3 +[Q52H,H69Y,F456L,T883I] XBB.1.5.69 443 338 76.3% 0 (consensus) XBB.1.5.69 443 15 3.4% 1 -[K417N] XBB.1.5.69 443 12 2.7% 1 +[H146K]-[H146Q] XBB.1.5.69 443 6 1.4% 1 +[G1124C] XBB.1.5.69 443 3 0.7% 1 +[L5F] B.1.1.374 442 123 27.8% 0 +[L452Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.374 442 57 12.9% 1 +[T19R,L452Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.374 442 34 7.7% 3 +[S98F,E180K,L452Q,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.374 442 32 7.2% 1 +[L452Q,S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.374 442 29 6.6% 2 +[L452Q,K1038Q,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.11.1 441 246 55.8% 0 +[D253G,F486S]-[G252V,F486P] (consensus) XBB.2.11.1 441 92 20.9% 1 +[D253G,F486S,L858I]-[G252V,F486P] XBB.2.11.1 441 9 2.0% 1 +[H146K,D253G,F486S]-[H146Q,G252V,F486P] XBB.2.11.1 441 9 2.0% 1 +[F486S]-[G252V,F486P] XBB.2.11.1 441 5 1.1% 1 +[D253G,T478R,F486S]-[G252V,T478K,F486P] BQ.1.16 440 302 68.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.16 440 41 9.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.16 440 9 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,F486P,F490S] BQ.1.16 440 6 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S691F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.16 440 6 1.4% 1 +[H69-,V70-,N211S,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BF.7.4.3 440 364 82.7% 0 +[H69-,V70-,F157L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.4.3 440 14 3.2% 1 +[H69-,V70-,F157L,V213G,G339D,L452R,F486V,E702K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.3 440 7 1.6% 1 +[H69-,V70-,F157L,V213G,D215H,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.3 440 7 1.6% 1 +[H69-,V70-,F157L,V213G,G339D,L452R,F486V,I1232V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.3 440 6 1.4% 1 +[S12F,H69-,V70-,F157L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.36.25 439 427 97.3% 0 +[S813I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.25 439 3 0.7% 1 +[K310R,S813I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.25 439 2 0.5% 1 +[S813I,L1203F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.25 439 2 0.5% 1 +[L5F,S813I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.25 439 2 0.5% 1 +[S813I,A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.587 439 396 90.2% 0 +[D178G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.587 439 5 1.1% 1 +[D178G,V503F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.587 439 4 0.9% 1 +[D178G,C1236F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.587 439 4 0.9% 1 +[L176F,D178G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.587 439 3 0.7% 1 +[D178G,D215H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.11 438 417 95.2% 0 +[A222V,D1163Y,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.11 438 3 0.7% 1 +[A222V,D1163Y,G1167V,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.11 438 2 0.5% 1 +[A222V,T376I,D1163Y,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.11 438 2 0.5% 1 +[A222V,D1163Y,G1167V,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.11 438 2 0.5% 1 +[A222V,D1163Y,G1167V,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AP.1 438 316 72.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AP.1 438 68 15.5% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AP.1 438 18 4.1% 1 +[A1026S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AP.1 438 11 2.5% 1 +[V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AP.1 438 8 1.8% 1 +[P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75.3 438 384 87.7% 0 +[T19R,E156G,F157-,R158-,A222V,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.75.3 438 19 4.3% 1 +[T19R,E156G,F157-,R158-,A222V,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75.3 438 13 3.0% 1 +[T19R,E156G,F157-,R158-,A222V,P251L,L452R,E583D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75.3 438 4 0.9% 1 +[T19R,E156G,F157-,R158-,A222V,P251L,L452R,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75.3 438 2 0.5% 1 +[T19R,E156G,F157-,R158-,A222V,P251L,L452R,P681R,D950N,L1203F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.39 438 323 73.7% 0 (consensus) XBB.1.5.39 438 12 2.7% 1 +[A67T] XBB.1.5.39 438 9 2.1% 1 +[K814R] XBB.1.5.39 438 6 1.4% 1 +[H146K]-[H146Q] XBB.1.5.39 438 5 1.1% 3 +[A27-,T284I]-[L24-,A27S] JN.1.45 437 228 52.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.45 437 69 15.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.45 437 16 3.7% 3 +[+16MPLF,R21T,H49Y,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1259Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.45 437 13 3.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.45 437 13 3.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1259Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] AU.1 437 383 87.6% 0 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AU.1 437 11 2.5% 1 +[L118F,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.1 437 10 2.3% 1 +[L5F,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.1 437 8 1.8% 1 +[N439K,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.1 437 5 1.1% 1 +[N439K,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.398 437 301 68.9% 0 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.398 437 19 4.3% 1 +[T95I,T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.398 437 10 2.3% 1 +[T95I,A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.398 437 8 1.8% 1 +[T95I,V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.398 437 6 1.4% 1 +[T95I,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.198 435 229 52.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.198 435 137 31.5% 1 +[R190M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.198 435 18 4.1% 3 +[R190M,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.198 435 8 1.8% 2 +[L5F,R190M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.198 435 6 1.4% 2 +[R190M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.3 433 160 37.0% 0 +[Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.3 433 154 35.6% 1 +[E583D,Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.3 433 33 7.6% 1 +[D253G,Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.3 433 24 5.5% 1 +[Q675R,F1062L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.3 433 13 3.0% 1 +[Q675R,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.38 432 159 36.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.38 432 131 30.3% 1 +[+16MPLF,R21T,G35S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.38 432 25 5.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T732I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.38 432 14 3.2% 5 +[R21T,G35S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.38 432 9 2.1% 2 +[+16MPLF,R21T,G35S,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] XAM 432 273 63.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAM 432 60 13.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] XAM 432 41 9.5% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAM 432 14 3.2% 5 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] XAM 432 5 1.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XBB.1.16.7 431 301 69.8% 0 +[E180V,T478R,T732I]-[T478K] (consensus) XBB.1.16.7 431 15 3.5% 1 +[R78M,E180V,T478R,T732I]-[T478K] XBB.1.16.7 431 13 3.0% 1 +[E180V,T478R,T732I,A845S]-[T478K] XBB.1.16.7 431 9 2.1% 1 +[E180V,D215G,T478R,T732I]-[T478K] XBB.1.16.7 431 8 1.9% 1 +[E180V,T478R,Q675H,T732I]-[T478K] BA.5.1.8 429 254 59.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.8 429 97 22.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.8 429 19 4.4% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.8 429 13 3.0% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,T791I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.8 429 3 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.42.1 427 378 88.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T719I,L938F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.42.1 427 17 4.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T719I,L938F,D950N,C1243W]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.42.1 427 7 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T719I,L938F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.42.1 427 7 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,T719I,L938F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.42.1 427 4 0.9% 3 +[T19R,T95I,E156G,F157-,R158-,S221A,L452R,P681R,T719I,L938F,D950N,D1118Y,C1243W]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.48 426 365 85.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.48 426 17 4.0% 1 +[T1231A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.48 426 5 1.2% 1 +[P26S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.48 426 5 1.2% 1 +[C1248F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.48 426 5 1.2% 1 +[D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.60 424 266 62.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S691F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.60 424 45 10.6% 2 +[H69-,V70-,M153T,V213G,G339D,K444T,L452R,F486V,S691F,R765S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.60 424 20 4.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S691F,R765S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.60 424 13 3.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S691F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,F486P,F490S] BQ.1.1.60 424 11 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S691F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.9 423 332 78.5% 0 (consensus) XBB.1.5.9 423 7 1.7% 1 +[G1124S] XBB.1.5.9 423 7 1.7% 2 +[G72R,T747I] XBB.1.5.9 423 5 1.2% 1 +[H146K]-[H146Q] XBB.1.5.9 423 5 1.2% 1 +[L5F] FL.4.6 421 312 74.1% 0 (consensus) FL.4.6 421 9 2.1% 2 +[S256L,Q613H] FL.4.6 421 6 1.4% 1 +[H146K]-[H146Q] FL.4.6 421 6 1.4% 2 +[L5F,H146K]-[H146Q] FL.4.6 421 6 1.4% 1 +[K97E] BA.2.9.7 420 381 90.7% 0 +[V213G,G339D,Q493R,S730F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.7 420 15 3.6% 1 +[V213G,G339D,Q493R,S730F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.9.7 420 3 0.7% 1 +[V213G,G339D,K444N,Q493R,S730F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.7 420 2 0.5% 1 +[V213G,G339D,Q493R,S730F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.9.7 420 2 0.5% 1 +[V213G,G339D,Q493R,S730F,D820N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.124.1 419 167 39.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.124.1 419 121 28.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124.1 419 35 8.4% 2 +[L18F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124.1 419 19 4.5% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124.1 419 11 2.6% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1133I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DN.1 419 296 70.6% 0 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.1 419 40 9.5% 1 +[H69-,V70-,K147N,N164I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1 419 11 2.6% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,E619K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1 419 9 2.1% 1 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1 419 7 1.7% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,N603I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBF.3 418 329 78.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.3 418 11 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.3 418 11 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,H519L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.3 418 9 2.2% 1 +[V6I,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.3 418 8 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] B.1.1.397 418 267 63.9% 0 +[D138Y,M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.397 418 25 6.0% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.397 418 23 5.5% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.397 418 8 1.9% 1 +[D138Y,M153T,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.397 418 7 1.7% 1 +[D138Y,M153T,E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.356 417 344 82.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.356 417 27 6.5% 1 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.356 417 13 3.1% 1 +[Q836H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.356 417 4 1.0% 1 +[L8W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.356 417 2 0.5% 2 +[L5F,Q677R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.3.5 416 222 53.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3.5 416 86 20.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.5 416 20 4.8% 1 +[H69-,V70-,L212F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.5 416 3 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.5 416 3 0.7% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.36 416 253 60.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.36 416 38 9.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.36 416 17 4.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I,E1092G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.36 416 11 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.36 416 8 1.9% 1 +[A67V,H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.523 415 275 66.3% 0 +[E156-,F157-,R158-,F306L,E484K,S494P,E780A,D839V,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.523 415 21 5.1% 1 +[E156-,F157-,R158-,N211K,F306L,E484K,S494P,E780A,D839V,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.523 415 14 3.4% 3 +[F306L,E484K,S494P,E780A,D839V,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.523 415 8 1.9% 1 +[E156-,F157-,R158-,F306L,E484K,S494P,E780S,D839V,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.523 415 3 0.7% 4 +[F306L,E484K,S494P,E780S,D839V,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.16 414 329 79.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.16 414 20 4.8% 1 +[H69-,V70-,V213G,T299I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.16 414 19 4.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S810L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.16 414 8 1.9% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.16 414 4 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBK.1 413 300 72.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBK.1 413 7 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P] XBK.1 413 6 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,S689I,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBK.1 413 5 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,P1162S,I1232T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBK.1 413 5 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T415N,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] BA.2.53 412 336 81.6% 0 +[V213G,G339D,Y449N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.53 412 13 3.2% 1 +[V213G,G339D,Y449N,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.53 412 10 2.4% 1 +[V213G,E324Q,G339D,Y449N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.53 412 8 1.9% 1 +[V213G,G339D,Y449N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.53 412 5 1.2% 4 +[V213G,G339D,Y449N,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBF.5 412 317 76.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.5 412 14 3.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.5 412 8 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,Q1201L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.5 412 6 1.5% 1 +[K147E,W152R,F157L,I210A,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.5 412 4 1.0% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,S939F,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] BA.1.1.7 411 257 62.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.7 411 18 4.4% 8 +[A67V,H69-,V70-,T95I,V143-,Y145-,E156G,F157-,R158-,N211-,L212I,+214EPE,G339D,R346K,Q493R,G496S,T547K,E554Q,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.7 411 12 2.9% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,E156G,F157-,R158-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.7 411 12 2.9% 1 +[Q14H,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.7 411 9 2.2% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,D1168N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] FE.1 411 157 38.2% 0 +[F456L] (consensus) FE.1 411 28 6.8% 1 +[F456L]-[R346T] FE.1 411 26 6.3% 2 +[F456L]-[R346T,K417N] FE.1 411 22 5.4% 2 +[F456L,E554K,A1070V] FE.1 411 15 3.6% 1 +[F456L,E554K] FR.1.1 411 336 81.8% 0 +[P82H,K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) FR.1.1 411 6 1.5% 2 +[P82H,E132Q,K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,I468V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.1 411 6 1.5% 1 +[P82H,K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P] FR.1.1 411 5 1.2% 1 +[L5F,P82H,K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.1 411 3 0.7% 1 +[P82H,K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,V595I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BF.7.4.2 410 218 53.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.4.2 410 94 22.9% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.2 410 27 6.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S929I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.2 410 11 2.7% 2 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.2 410 8 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.35 407 324 79.6% 0 +[V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.35 407 15 3.7% 1 +[V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.35 407 6 1.5% 1 +[L5F,V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.35 407 4 1.0% 1 +[V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N679K] BA.2.35 407 4 1.0% 1 +[V213G,G339D,L452R,Q493R,L1200I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.298 407 259 63.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.298 407 40 9.8% 1 +[T415A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.298 407 13 3.2% 1 +[A575S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.298 407 13 3.2% 2 +[I210V,I934M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.298 407 8 2.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BW.1.1.1 406 339 83.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BW.1.1.1 406 6 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BW.1.1.1 406 6 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,S1147L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1.1.1 406 4 1.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,V642G]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1.1.1 406 3 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,Q1201H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.1.44 406 160 39.4% 0 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.44 406 135 33.3% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.44 406 38 9.4% 2 +[H69-,V70-,Q183R,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.44 406 4 1.0% 1 +[H69-,V70-,Q183R,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.44 406 4 1.0% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,P809S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BE.1.4.2 403 282 70.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.4.2 403 42 10.4% 1 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4.2 403 15 3.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.4.2 403 9 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4.2 403 8 2.0% 1 +[H69-,V70-,V213G,K304R,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] FL.1.3 402 211 52.5% 0 +[A701V] (consensus) FL.1.3 402 46 11.4% 1 +[A701V]-[T478K] FL.1.3 402 32 8.0% 1 +[A701V,V1060I] FL.1.3 402 16 4.0% 1 +[G184D,A701V] FL.1.3 402 9 2.2% 1 +[L5F,A701V] CN.2 401 360 89.8% 0 +[Y28H,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CN.2 401 6 1.5% 2 +[Y28H,H69-,V70-,D178N,G184V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CN.2 401 5 1.2% 1 +[L5F,Y28H,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CN.2 401 4 1.0% 1 +[Y28H,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] CN.2 401 3 0.7% 1 +[Y28H,H69-,V70-,V213G,G339D,L452R,N481S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] GP.2 399 211 52.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) GP.2 399 94 23.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,D1260E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GP.2 399 6 1.5% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,A958S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GP.2 399 5 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GP.2 399 4 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CJ.1.2 399 224 56.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) CJ.1.2 399 83 20.8% 1 +[K147E,W152Q,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.2 399 7 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.2 399 6 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P] CJ.1.2 399 5 1.3% 1 +[K147E,W152R,M153I,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] EF.1.2 398 221 55.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EF.1.2 398 85 21.4% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1.2 398 8 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] EF.1.2 398 7 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EF.1.2 398 6 1.5% 2 +[H69-,V70-,V213G,D253G,V289I,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] HK.11 398 187 47.0% 0 +[Q52H,G184S,F456L] (consensus) HK.11 398 84 21.1% 1 +[Q52H,G184S,L455F,F456L] HK.11 398 22 5.5% 2 +[Q52H,G184S,L455F,F456L,T478R]-[T478K] HK.11 398 11 2.8% 2 +[Q52H,M153T,G184S,L455F,F456L] HK.11 398 9 2.3% 5 +[Q52H,L54F,H146K,M153T,G184S,L455F,F456L,T478N]-[H146Q,T478K] B.1.160.7 398 335 84.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.7 398 22 5.5% 1 +[S810L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.7 398 4 1.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.7 398 4 1.0% 1 +[A831V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.7 398 3 0.8% 3 +[G482S,Q613H,A871S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.3.2 397 250 63.0% 0 (consensus) FL.3.2 397 18 4.5% 1 +[D80Y] FL.3.2 397 11 2.8% 1 +[L560Q] FL.3.2 397 10 2.5% 2 -[G142D,K417N] FL.3.2 397 9 2.3% 1 +[T478R]-[T478K] AY.11 397 359 90.4% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.11 397 7 1.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V976F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.11 397 5 1.3% 1 +[L5F,T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.11 397 5 1.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.11 397 3 0.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,D574Y,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.100 397 151 38.0% 0 +[V1122M] (consensus) XBB.1.5.100 397 70 17.6% 1 +[H146K,V1122M]-[H146Q] XBB.1.5.100 397 17 4.3% 1 +[T259I,V1122M] XBB.1.5.100 397 13 3.3% 3 +[T478R,L552I,V1122M,D1168H]-[T478K] XBB.1.5.100 397 7 1.8% 1 +[L5F,V1122M] BA.5.2.56 395 250 63.3% 0 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.56 395 17 4.3% 3 +[H69-,V70-,H146-,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.56 395 17 4.3% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V,I624M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.56 395 15 3.8% 1 +[H69-,V70-,K182E,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.56 395 11 2.8% 2 +[H69-,V70-,H146-,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.2.4 394 238 60.4% 0 (consensus) FL.2.4 394 51 12.9% 1 +[G1099D] FL.2.4 394 12 3.0% 1 +[G181A] FL.2.4 394 5 1.3% 1 +[F456L] FL.2.4 394 5 1.3% 1 +[G1124V] XBB.1.42.1 391 196 50.1% 0 +[T478R,Q613H]-[T478K] (consensus) XBB.1.42.1 391 15 3.8% 1 +[H146K,T478R,Q613H]-[H146Q,T478K] XBB.1.42.1 391 14 3.6% 1 +[D80G,T478R,Q613H]-[T478K] XBB.1.42.1 391 11 2.8% 2 +[M153V,S254F,T478R,Q613H]-[T478K] XBB.1.42.1 391 11 2.8% 1 +[Q218R,T478R,Q613H]-[T478K] BA.2.75.3 391 186 47.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75.3 391 19 4.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.3 391 16 4.1% 1 +[L84I,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.3 391 14 3.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.3 391 13 3.3% 1 +[K97Q,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] XBB.2.3.5 391 233 59.6% 0 +[D253G,T478N,P521S]-[G252V,T478K] (consensus) XBB.2.3.5 391 24 6.1% 1 +[D253G,T478N,P521S]-[G252V,R408S,T478K] XBB.2.3.5 391 12 3.1% 1 +[D253G,T478N,P521S]-[G252V,K417N,T478K] XBB.2.3.5 391 9 2.3% 1 +[R190S,D253G,T478N,P521S]-[G252V,T478K] XBB.2.3.5 391 6 1.5% 1 +[D253G,T478N,P521S,P812S]-[G252V,T478K] XBB.1.5.96 390 248 63.6% 0 (consensus) XBB.1.5.96 390 31 7.9% 1 +[I1114V] XBB.1.5.96 390 11 2.8% 1 -[K417N] XBB.1.5.96 390 8 2.1% 1 +[H146K]-[H146Q] XBB.1.5.96 390 7 1.8% 1 +[V1228L] B.1.1.448 389 281 72.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.448 389 8 2.1% 1 +[N658D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.448 389 8 2.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.448 389 5 1.3% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.448 389 4 1.0% 3 +[H69-,V70-,S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.37 389 370 95.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.37 389 3 0.8% 1 +[M731I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.37 389 2 0.5% 1 +[L229F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.37 389 2 0.5% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.37 389 2 0.5% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.42 389 183 47.0% 0 +[Q613H] (consensus) XBB.1.42 389 49 12.6% 1 +[Q613H,L1049I] XBB.1.42 389 26 6.7% 2 +[F456L,T478R,Q613H]-[T478K] XBB.1.42 389 12 3.1% 2 +[T259I,Y451H,Q613H] XBB.1.42 389 9 2.3% 1 +[R190S,Q613H] XBB.1.16.13 389 314 80.7% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.13 389 6 1.5% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.13 389 5 1.3% 1 +[E180V,T478R]-[K417N,T478K] XBB.1.16.13 389 3 0.8% 1 +[E180V,T478R,A1020V]-[T478K] XBB.1.16.13 389 3 0.8% 1 +[E180V]-[T478K] CM.4 388 256 66.0% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.4 388 34 8.8% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444T,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.4 388 12 3.1% 1 +[M153T,N164K,T208M,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.4 388 7 1.8% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,R346K,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.4 388 6 1.5% 2 +[A27-,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[L24-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] B.1.443 387 260 67.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.443 387 79 20.4% 1 +[D796G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.443 387 20 5.2% 1 +[A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.443 387 5 1.3% 1 +[E654K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.443 387 4 1.0% 1 +[A1070V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.59 387 167 43.2% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.59 387 146 37.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.59 387 19 4.9% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,D1260Y,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.59 387 7 1.8% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,M1229I,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.59 387 5 1.3% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.2.4 387 194 50.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.4 387 123 31.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.4 387 7 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.2.4 387 6 1.6% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.2.4 387 4 1.0% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A1070T,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] DV.3 384 329 85.7% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.3 384 7 1.8% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I794L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.3 384 6 1.6% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,A831V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.3 384 4 1.0% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] DV.3 384 4 1.0% 1 +[L5F,K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JN.1.46 384 212 55.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.46 384 39 10.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.46 384 24 6.2% 12 +[N17M,+17P,+18FNFI,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.46 384 20 5.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,G268S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.46 384 18 4.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,A123S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] CQ.1 384 347 90.4% 0 +[H69-,V70-,P209L,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CQ.1 384 4 1.0% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] CQ.1 384 4 1.0% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,L452R,F486V,A831V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CQ.1 384 3 0.8% 2 +[H69-,V70-,P209L,V213G,G339D,K444R,L452R,F486V]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] CQ.1 384 2 0.5% 1 +[H69-,V70-,P209L,V213G,D215H,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.2 383 273 71.3% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BE.4.2 383 57 14.9% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.4.2 383 7 1.8% 3 +[H69-,V70-,D253Y,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.4.2 383 7 1.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BE.4.2 383 3 0.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,P812L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.91 383 302 78.9% 0 +[D839Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.91 383 32 8.4% 1 +[D839Y,Y1272F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.91 383 10 2.6% 1 +[F186S,D839Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.91 383 6 1.6% 2 +[L5F,D839Y,Y1272F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.91 383 5 1.3% 1 +[L5F,D839Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.4 383 318 83.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.4 383 11 2.9% 1 +[V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.4 383 8 2.1% 1 +[V213G,G339D,Q493R,R1185L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.4 383 6 1.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.4 383 5 1.3% 1 +[V213G,G339D,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.289 383 312 81.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.289 383 43 11.2% 1 +[T1238I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.289 383 5 1.3% 1 +[A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.289 383 4 1.0% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.289 383 4 1.0% 1 +[I834T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.121 382 350 91.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.121 382 7 1.8% 2 +[T76S,P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.121 382 4 1.0% 1 +[P209T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.121 382 2 0.5% 1 +[N556K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.121 382 2 0.5% 1 +[P621S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CZ.2 379 282 74.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) CZ.2 379 13 3.4% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,T470I,F486V,A688V,D1146N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CZ.2 379 11 2.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V,D1260Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CZ.2 379 7 1.8% 2 +[H69-,V70-,V213G,N282I,G339D,K444T,L452R,F486V,A688V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CZ.2 379 7 1.8% 1 +[H69-,V70-,D80Y,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FK.1.1.2 379 257 67.8% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.1.2 379 23 6.1% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,A684V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1.2 379 21 5.5% 1 +[T22S,K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1.2 379 20 5.3% 3 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,K529N,T547K,Q613H,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1.2 379 10 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CK.1.5 378 295 78.0% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1.5 378 24 6.3% 1 +[L5F,H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.5 378 7 1.9% 1 +[H69-,V70-,N148D,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.5 378 7 1.9% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,F1103S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.5 378 5 1.3% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BA.5.2.32 377 170 45.1% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.32 377 25 6.6% 5 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.32 377 22 5.8% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] BA.5.2.32 377 13 3.4% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.32 377 13 3.4% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,D796Y] AY.5.5 376 207 55.1% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5.5 376 67 17.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.5 376 8 2.1% 1 +[T19R,E156G,F157-,R158-,W258L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.5 376 8 2.1% 1 +[T19R,E156G,F157-,R158-,L452R,T553I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.5 376 7 1.9% 3 +[T19R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.58 373 344 92.2% 0 +[V213G,G339D,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.58 373 5 1.3% 1 +[V213G,G339D,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.58 373 4 1.1% 1 +[Q183R,V213G,G339D,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.58 373 4 1.1% 1 +[V213G,G339D,Q493R,A1080S,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.58 373 2 0.5% 1 +[V213G,G339D,Q493R,T573I,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBF.2 373 303 81.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.2 373 10 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K529N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.2 373 9 2.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,P631S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.2 373 8 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,V622F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.2 373 6 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G1099D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBB.1.5.57 372 213 57.3% 0 (consensus) XBB.1.5.57 372 47 12.6% 1 +[T883I] XBB.1.5.57 372 9 2.4% 1 +[H146K]-[H146Q] XBB.1.5.57 372 8 2.2% 1 +[S704L] XBB.1.5.57 372 5 1.3% 2 +[K97N,G257D] B.1.36.21 372 272 73.1% 0 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.21 372 58 15.6% 1 +[L54F,D1146H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.21 372 9 2.4% 1 +[L54F,I818V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.21 372 8 2.2% 1 +[L54F,S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.21 372 6 1.6% 1 +[L54F,T1076I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.29 372 251 67.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.29 372 64 17.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,K1191N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.29 372 12 3.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.29 372 12 3.2% 3 +[H69-,V70-,H146-,G181E,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.29 372 12 3.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.66 372 311 83.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.66 372 17 4.6% 1 +[V213G,D215G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.66 372 6 1.6% 1 +[V213G,G339D,Q493R,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.66 372 5 1.3% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.66 372 5 1.3% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] GK.1.3 372 169 45.4% 0 +[L455F,F456L,T573I,S704L,K1266R] (consensus) GK.1.3 372 91 24.5% 2 +[L455F,F456L,S704L] GK.1.3 372 30 8.1% 1 +[L455F,F456L,T573I,S704L] GK.1.3 372 8 2.2% 1 +[H146K,L455F,F456L,T573I,S704L,K1266R]-[H146Q] GK.1.3 372 5 1.3% 3 +[L455F,F456L,S704L,S939F] BQ.1.1.53 371 142 38.3% 0 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.53 371 111 29.9% 1 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.53 371 16 4.3% 1 +[H69-,V70-,N185D,V213G,G339D,N354K,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.53 371 6 1.6% 2 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,K1045N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.53 371 6 1.6% 2 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BF.7.8 370 275 74.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.8 370 11 3.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.8 370 7 1.9% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,T547K,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.8 370 7 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.8 370 5 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547K,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BL.2 370 168 45.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BL.2 370 40 10.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,F486P,F490S] BL.2 370 17 4.6% 1 +[K147E,W152R,F157L,I210V,V213G,L216F,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.2 370 15 4.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.2 370 14 3.8% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XAS 370 269 72.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAS 370 15 4.1% 1 +[H69-,V70-,K147E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAS 370 11 3.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAS 370 10 2.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1070S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAS 370 6 1.6% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XDQ 368 182 49.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDQ 368 41 11.1% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDQ 368 16 4.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDQ 368 12 3.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDQ 368 11 3.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] BF.37 368 307 83.4% 0 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.37 368 33 9.0% 1 +[H69-,V70-,V213G,S256L,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.37 368 4 1.1% 1 +[H69-,V70-,V213G,G261D,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.37 368 4 1.1% 1 +[H69-,V70-,G75V,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.37 368 3 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] A.2.2 368 350 95.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2.2 368 6 1.6% 1 +[A831S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.2 368 2 0.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.2 368 2 0.5% 1 +[Q690L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.2 368 1 0.3% 1 +[E1207D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAC 368 331 89.9% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAC 368 5 1.4% 2 +[K147N,M153I,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAC 368 5 1.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] XAC 368 3 0.8% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAC 368 2 0.5% 1 +[V213G,G339D,Q493R,L546V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.55 367 303 82.6% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.55 367 18 4.9% 1 +[A222V,E281Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.55 367 9 2.5% 1 +[A222V,E654A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.55 367 7 1.9% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.55 367 7 1.9% 1 +[A222V,S711F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.217 367 267 72.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.217 367 27 7.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.217 367 26 7.1% 1 +[K986R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.217 367 16 4.4% 1 +[T778I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.217 367 3 0.8% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.4.6 365 227 62.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.4.6 365 21 5.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.6 365 21 5.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.6 365 14 3.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.6 365 4 1.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] XBK 365 244 66.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBK 365 20 5.5% 1 +[K147E,W152R,F157L,I210V,V213G,D215H,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBK 365 12 3.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T573I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBK 365 6 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,I233V,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBK 365 4 1.1% 3 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P] EU.1.1.1 365 283 77.5% 0 +[I410V,P521S] (consensus) EU.1.1.1 365 9 2.5% 1 +[I410V,P521S]-[K417N] EU.1.1.1 365 4 1.1% 1 +[I410V,P521S,D796H]-[D796Y] EU.1.1.1 365 4 1.1% 1 +[I410V,P521S,C1240Y] EU.1.1.1 365 4 1.1% 1 +[G257D,I410V,P521S] FL.19 365 243 66.6% 0 (consensus) FL.19 365 12 3.3% 1 +[H146K]-[H146Q] FL.19 365 10 2.7% 1 +[L754F] FL.19 365 6 1.6% 1 +[Q14H] FL.19 365 6 1.6% 1 +[Q613H] XBB.1.5.75 363 264 72.7% 0 (consensus) XBB.1.5.75 363 8 2.2% 1 +[H146K]-[H146Q] XBB.1.5.75 363 5 1.4% 1 -[K417N] XBB.1.5.75 363 4 1.1% 1 +[L249S] XBB.1.5.75 363 4 1.1% 1 -[H146Q] XBB.1.16.10 363 196 54.0% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.10 363 27 7.4% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.10 363 23 6.3% 1 +[L84I,E180V,T478R]-[T478K] XBB.1.16.10 363 19 5.2% 1 +[E180V,T478R,S1252F]-[T478K] XBB.1.16.10 363 14 3.9% 1 +[E180V,Y248-,T478R]-[T478K] B.1.1.337 362 300 82.9% 0 +[A1078T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.337 362 16 4.4% 1 +[T22A,A1078T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.337 362 7 1.9% 1 +[H207R,A1078T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.337 362 7 1.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.337 362 5 1.4% 1 +[Q779R,A1078T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.54 362 180 49.7% 0 +[T29I,H69-,V70-,F186S,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.54 362 75 20.7% 1 +[H69-,V70-,F186S,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.54 362 21 5.8% 1 +[T29I,H69-,V70-,F186S,V213G,A260S,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.54 362 8 2.2% 2 +[T29I,H69-,V70-,F186S,V213G,A260S,G339D,K444T,L452R,F486V,S1170Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.54 362 7 1.9% 2 +[H69-,V70-,F186S,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.25 362 271 74.9% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.25 362 18 5.0% 1 +[V213G,G339D,Q493R,E780D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.25 362 14 3.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.25 362 13 3.6% 1 +[V213G,G339D,Q493R,P1143S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.25 362 6 1.7% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AU.3 362 318 87.8% 0 +[N439K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AU.3 362 11 3.0% 2 +[N439K,P681R,A892S,M1233V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.3 362 4 1.1% 1 +[T22I,N439K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.3 362 4 1.1% 1 +[N439K,P681R,H1083Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AU.3 362 2 0.6% 1 +[N439K,P681R,C1236F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HR.1 361 134 37.1% 0 +[K304N,T478R,E780D]-[T478K] HR.1 361 56 15.5% 2 +[T478R]-[T478K] HR.1 361 42 11.6% 2 +[A67S,K304N,T478R]-[T478K] HR.1 361 40 11.1% 1 +[K304N,T478R]-[T478K] (consensus) HR.1 361 16 4.4% 3 +[T478R,A623V]-[T478K] B.1.1.241 360 294 81.7% 0 +[V3G,L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.241 360 6 1.7% 1 +[V3G,L5F,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.241 360 4 1.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.241 360 4 1.1% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.241 360 4 1.1% 1 +[V3G,L5F,C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.2.1 359 240 66.9% 0 (consensus) FL.2.1 359 5 1.4% 1 +[A1078S] FL.2.1 359 5 1.4% 1 +[A852T] FL.2.1 359 5 1.4% 2 +[N148T,T573I] FL.2.1 359 5 1.4% 1 +[A701V] XBB.1.16.12 359 233 64.9% 0 +[Q52H,E180V,T478R]-[T478K] (consensus) XBB.1.16.12 359 26 7.2% 1 +[Q52H,H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.12 359 5 1.4% 2 +[Q52H,N74S,H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.12 359 5 1.4% 1 +[Q52H,G72E,E180V,T478R]-[T478K] XBB.1.16.12 359 4 1.1% 1 +[Q52H,E180V,T478R]-[K417N,T478K] B.1.177.76 358 339 94.7% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.76 358 3 0.8% 1 +[A222V,L1200F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.76 358 2 0.6% 1 +[A222V,D1146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.76 358 2 0.6% 1 +[N164T,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.76 358 1 0.3% 1 +[A222V,P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.39 358 284 79.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.39 358 16 4.5% 1 +[V915I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.39 358 13 3.6% 1 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.39 358 7 2.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.39 358 7 2.0% 2 +[L5F,V915I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.57 358 208 58.1% 0 +[H69-,V70-,V213G,S256A,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.57 358 42 11.7% 1 +[H69-,V70-,V213G,S256A,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.57 358 29 8.1% 1 +[H69-,V70-,K147E,V213G,S256A,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.57 358 20 5.6% 2 +[H69-,V70-,V213G,S256A,G339D,K444T,L452R,F486V,H1101Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.57 358 10 2.8% 2 +[H69-,V70-,V213G,S256A,G339D,K444T,L452R,F486V,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] JN.4 358 257 71.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.4 358 11 3.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.4 358 10 2.8% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.4 358 10 2.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.4 358 5 1.4% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KV.2 358 214 59.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KV.2 358 98 27.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KV.2 358 6 1.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] KV.2 358 5 1.4% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KV.2 358 2 0.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,I1183V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] GW.5.1.1 357 210 58.8% 0 +[F79S,L455F,F456L,A475V,T478I,E554K]-[T478K] (consensus) GW.5.1.1 357 32 9.0% 2 +[F79S,N185I,F186-,L455F,F456L,A475V,T478I,E554K]-[T478K] GW.5.1.1 357 27 7.6% 1 +[F79S,F186S,L455F,F456L,A475V,T478I,E554K]-[T478K] GW.5.1.1 357 10 2.8% 1 +[F79S,L455F,F456L,A475V,T478I,E554K,S704L]-[T478K] GW.5.1.1 357 5 1.4% 1 +[F79S,R408G,L455F,F456L,A475V,T478I,E554K]-[R408S,T478K] BA.4.6.3 356 212 59.6% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,N658S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BA.4.6.3 356 53 14.9% 1 +[H69-,V70-,V213G,Y248S,G339D,K444N,L452R,F486V,N658S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.4.6.3 356 18 5.1% 1 +[H69-,V70-,V213G,D253G,G339D,K444N,L452R,F486V,N658S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.4.6.3 356 15 4.2% 2 +[H69-,V70-,F157S,V213G,G339D,K444N,V445A,L452R,F486V,N658S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.4.6.3 356 4 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,K444N,L452R,F486V,N658S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.5.2.52 355 210 59.2% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.52 355 40 11.3% 1 +[H69-,V70-,I128V,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.52 355 12 3.4% 2 +[H69-,V70-,H146-,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.52 355 11 3.1% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.52 355 9 2.5% 1 +[H69-,V70-,Y145H,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.516 354 331 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.516 354 8 2.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.516 354 3 0.8% 1 +[P9S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.516 354 2 0.6% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.516 354 1 0.3% 1 +[I203M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JE.1.1 354 126 35.6% 0 +[Q52R,K182N,D253G,N450D,T478R,P521S,V1122A]-[G252V,T478K] (consensus) JE.1.1 354 46 13.0% 1 +[Q52R,K182N,D253G,N450D,T478R,P521S,E554K,V1122A]-[G252V,T478K] JE.1.1 354 33 9.3% 1 +[Q52R,K182N,D253G,N450D,T478R,P521S]-[G252V,T478K] JE.1.1 354 11 3.1% 1 +[Q52R,K182N,D215H,D253G,N450D,T478R,P521S,V1122A]-[G252V,T478K] JE.1.1 354 6 1.7% 2 +[Q52R,K182N,D253G,N450D,T478R,P521S,E554K,V1122A,D1163G]-[G252V,T478K] XBB.1.22.2 354 223 63.0% 0 (consensus) XBB.1.22.2 354 15 4.2% 1 +[V445L]-[V445P] XBB.1.22.2 354 8 2.3% 1 -[K417N] XBB.1.22.2 354 8 2.3% 1 +[T547I] XBB.1.22.2 354 6 1.7% 1 +[T76I] BF.1.1 353 321 90.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.1.1 353 6 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S884C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.1.1 353 5 1.4% 2 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V,I1130T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.1.1 353 3 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BF.1.1 353 3 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N532Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.102 351 209 59.5% 0 (consensus) XBB.1.5.102 351 16 4.6% 2 -[R346T,K417N] XBB.1.5.102 351 11 3.1% 1 -[R408S] XBB.1.5.102 351 10 2.8% 1 +[A688V] XBB.1.5.102 351 7 2.0% 1 -[R346T] DE.1 349 291 83.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DE.1 349 18 5.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] DE.1 349 9 2.6% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DE.1 349 4 1.1% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DE.1 349 4 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.523 349 205 58.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.523 349 73 20.9% 2 +[A263V,N1178D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.523 349 17 4.9% 1 +[V159I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.523 349 7 2.0% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.523 349 6 1.7% 1 +[H1159R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GD.1 349 214 61.3% 0 +[Y453F,F486S]-[F486P] (consensus) GD.1 349 16 4.6% 3 +[H146K,K356T,Y453F,F486S,I1132T]-[H146Q,F486P] GD.1 349 11 3.2% 1 +[H146K,Y453F,F486S]-[H146Q,F486P] GD.1 349 11 3.2% 1 +[Y453F,F486S]-[K417N,F486P] GD.1 349 5 1.4% 1 +[T323I,Y453F,F486S]-[F486P] B.1.480 348 203 58.3% 0 +[N439K,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.480 348 38 10.9% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.480 348 13 3.7% 2 +[S939F,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.480 348 12 3.4% 2 +[D427V,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.480 348 12 3.4% 1 +[N439K,E1207D,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DQ.1 346 265 76.6% 0 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DQ.1 346 13 3.8% 1 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V,V1094A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DQ.1 346 13 3.8% 2 +[H69-,V70-,K147N,V213G,S256L,G339D,L452R,T478I,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,T478K,F486P,F490S] DQ.1 346 7 2.0% 1 +[H69-,V70-,K147N,V213G,R214L,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DQ.1 346 4 1.2% 1 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] EG.14 346 234 67.6% 0 (consensus) EG.14 346 32 9.2% 1 +[Q677H] EG.14 346 12 3.5% 1 +[H146K]-[H146Q] EG.14 346 4 1.2% 2 +[N185I,F186-] EG.14 346 3 0.9% 1 +[L5F] BA.2.34 346 256 74.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.34 346 51 14.7% 1 +[L176F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.34 346 4 1.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.34 346 3 0.9% 1 +[P82S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.34 346 3 0.9% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XG 345 176 51.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XG 345 76 22.0% 1 +[V213G,A262S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XG 345 33 9.6% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XG 345 21 6.1% 1 +[E96D,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XG 345 17 4.9% 5 +[V213G,A262S,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.10 345 257 74.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.10 345 13 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.10 345 12 3.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.10 345 9 2.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.10 345 5 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] BE.1.4.1 345 279 80.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.4.1 345 21 6.1% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4.1 345 8 2.3% 1 +[H69-,V70-,G75A,V213G,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4.1 345 7 2.0% 2 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V,T547I,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4.1 345 6 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A701V,A846S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EG.5.2.1 345 226 65.5% 0 +[F456L,S704L] (consensus) EG.5.2.1 345 38 11.0% 1 +[L5F,F456L,S704L] EG.5.2.1 345 33 9.6% 1 +[G75A,F456L,S704L] EG.5.2.1 345 5 1.4% 1 +[T22I,F456L,S704L] EG.5.2.1 345 5 1.4% 1 +[F456L,S704L,T1136I] AY.81 344 208 60.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,A694V,D950N,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.81 344 46 13.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A694V,D950N,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.81 344 19 5.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A694V,T716I,D950N,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.81 344 6 1.7% 3 +[T19R,E156G,F157-,R158-,L216F,L452R,P681R,A694V,F855S,D950N,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.81 344 5 1.5% 2 +[T19R,E156G,F157-,R158-,L216F,L452R,P681R,A694V,F855S,D950N,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBE 344 310 90.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XBE 344 4 1.2% 2 +[H69-,V70-,V213G,H245Y,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBE 344 4 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XBE 344 2 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,E1017D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBE 344 2 0.6% 2 +[H69-,V70-,L212S,V213G,G339D,L452R,F486V,A892V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.297 343 207 60.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.297 343 35 10.2% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.297 343 15 4.4% 1 +[P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.297 343 13 3.8% 1 +[D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.297 343 12 3.5% 1 +[A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.16.3 343 180 52.5% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.3 343 35 10.2% 1 +[E180V,T478R,D843N]-[T478K] XBB.1.16.3 343 26 7.6% 1 +[E180V,T478R,P521S]-[T478K] XBB.1.16.3 343 11 3.2% 1 +[E180V,I210-,T478R]-[T478K] XBB.1.16.3 343 9 2.6% 1 +[E96A,E180V,T478R]-[T478K] B.1.301 343 290 84.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.301 343 18 5.2% 1 +[S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.301 343 5 1.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.301 343 5 1.5% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.301 343 2 0.6% 2 +[I770V,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.80 343 254 74.1% 0 (consensus) XBB.1.5.80 343 8 2.3% 1 +[G446I]-[G446S] XBB.1.5.80 343 6 1.7% 1 +[A1078T] XBB.1.5.80 343 6 1.7% 1 +[Q836R] XBB.1.5.80 343 4 1.2% 1 +[Q677H] BA.4.5 342 283 82.7% 0 +[H69-,V70-,G181E,V213G,G339D,L452R,F486V,N658S,Q1201L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.5 342 14 4.1% 1 +[L5F,H69-,V70-,G181E,V213G,G339D,L452R,F486V,N658S,Q1201L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.5 342 6 1.8% 1 +[H69-,V70-,G181E,V213G,G339D,L452R,F486V,N658S,D1084Y,Q1201L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.5 342 4 1.2% 1 +[H69-,V70-,G181E,V213G,G339D,L452R,F486V,N658S,Q1201L,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.5 342 4 1.2% 1 +[H69-,V70-,G181E,V213G,G339D,L452R,F486V,N658S,E1017G,Q1201L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] C.18 342 279 81.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.18 342 10 2.9% 1 +[N188S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.18 342 3 0.9% 1 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.18 342 3 0.9% 2 +[W258L,A263S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.18 342 3 0.9% 1 +[G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.7.2 342 252 73.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.7.2 342 25 7.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.7.2 342 6 1.8% 1 +[+16MPLF,R21T,S50L,Q52K,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.7.2 342 4 1.2% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.7.2 342 4 1.2% 5 +[R21T,S50L,Q52K,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BE.7 342 201 58.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.7 342 33 9.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1104L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.7 342 7 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BE.7 342 7 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.7 342 4 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.43 341 278 81.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.43 341 12 3.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.43 341 6 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H,S1021F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.43 341 4 1.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.43 341 2 0.6% 2 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V,Q613H,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] HK.3.3 339 210 61.9% 0 +[Q52H,S256L,L455F,F456L] (consensus) HK.3.3 339 15 4.4% 1 +[Q14H,Q52H,S256L,L455F,F456L] HK.3.3 339 10 2.9% 1 +[Q52H,S256L,L455F,F456L,T478R]-[T478K] HK.3.3 339 6 1.8% 1 +[Q52H,S256L,L455F,F456L,G482R] HK.3.3 339 6 1.8% 1 +[Q52H,S256L,L455F,F456L,N481S] BA.5.2.62 339 90 26.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.62 339 58 17.1% 2 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V,A653V,A706V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.62 339 51 15.0% 3 +[H69-,V70-,V213G,R214L,G339D,N450D,L452R,F486V,A653V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.62 339 47 13.9% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.62 339 8 2.4% 2 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,A653V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.78 338 108 32.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.78 338 59 17.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.78 338 28 8.3% 1 +[T19R,T95I,V143F,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.78 338 28 8.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,I834T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.78 338 14 4.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,K814M,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.11.4 338 262 77.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.11.4 338 15 4.4% 1 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.4 338 7 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S704L,D1084Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.4 338 7 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.4 338 6 1.8% 1 +[P9S,H69-,V70-,V213G,G339D,L452R,F486V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.210 337 250 74.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.210 337 9 2.7% 1 +[A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.210 337 8 2.4% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.210 337 6 1.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.210 337 4 1.2% 2 +[R214L,A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.235 337 318 94.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.235 337 7 2.1% 1 +[A1056V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.235 337 5 1.5% 1 +[A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.235 337 1 0.3% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.235 337 1 0.3% 1 +[D215G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.16.14 336 238 70.8% 0 +[E180V,L452Q,T478R]-[T478K] (consensus) XBB.1.16.14 336 17 5.1% 1 +[H146K,E180V,L452Q,T478R]-[H146Q,T478K] XBB.1.16.14 336 14 4.2% 1 +[E180V,G181V,L452Q,T478R]-[T478K] XBB.1.16.14 336 10 3.0% 1 +[E180V,L452Q,T478R,R567K]-[T478K] XBB.1.16.14 336 6 1.8% 2 +[E180V,L452Q,P463S,T478R,Q613H]-[T478K] CP.8 335 244 72.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.8 335 13 3.9% 1 +[F55Y,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.8 335 11 3.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1078S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.8 335 6 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,M1229I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.8 335 4 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.76 335 86 25.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.76 335 50 14.9% 1 +[T19R,E156G,F157-,R158-,L452R,T573I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.76 335 25 7.5% 2 +[T19R,E156G,F157-,R158-,L452R,T573I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.76 335 18 5.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.76 335 14 4.2% 2 +[T19R,E156G,F157-,R158-,L452R,T573I,P681R,A771S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.640.1 335 239 71.3% 0 +[P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,I210T,R346S,N394S,Y449N,F490R,T859N,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.640.1 335 11 3.3% 9 +[P9L,E96Q,R190S,I210T,R346S,N394S,Y449N,F490R,T859N,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.640.1 335 11 3.3% 1 +[P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,I210T,R346S,N394S,Y449N,F490R,T859N,D936H,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.640.1 335 6 1.8% 2 +[P9L,D88Y,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,I210T,R346S,N394S,Y449N,F490R,S704L,T859N,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.640.1 335 6 1.8% 1 +[P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,I210T,R346S,N394S,Y449N,F490R,S704L,T859N,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.98.1.1 335 101 30.1% 0 +[L18F,T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1.1 335 94 28.1% 1 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.98.1.1 335 54 16.1% 2 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1.1 335 20 6.0% 2 +[T19R,E156G,F157-,R158-,G181V,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1.1 335 10 3.0% 2 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N,K1266R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.574 335 313 93.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.574 335 7 2.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.574 335 4 1.2% 4 +[V143-,Y145-]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.574 335 2 0.6% 1 +[L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.574 335 1 0.3% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.399 334 178 53.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.399 334 61 18.3% 1 +[V382L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.399 334 23 6.9% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.399 334 19 5.7% 1 +[V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.399 334 13 3.9% 1 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.350 334 251 75.1% 0 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.350 334 37 11.1% 1 +[A892S,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.350 334 13 3.9% 1 +[H49Y,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.350 334 8 2.4% 1 +[M177T,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.350 334 7 2.1% 1 +[A771S,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.12 334 228 68.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.12 334 40 12.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.12 334 10 3.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.12 334 8 2.4% 1 +[Y28H,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.12 334 3 0.9% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N679K,P681H] JD.1.1.3 334 220 65.9% 0 +[L455F,F456L,T470N,A475V] (consensus) JD.1.1.3 334 17 5.1% 1 +[F2L,L455F,F456L,T470N,A475V] JD.1.1.3 334 14 4.2% 1 +[L455F,F456L,T470N,A475V,A1020S] JD.1.1.3 334 7 2.1% 2 +[T95I,L455F,F456L,T470N,A475V]-[T19I] JD.1.1.3 334 5 1.5% 1 +[K310R,L455F,F456L,T470N,A475V] FL.7 332 184 55.4% 0 +[T51I] (consensus) FL.7 332 30 9.0% 3 +[T51I,H69-,V70-,A845S] FL.7 332 27 8.1% 1 +[Q14R,T51I] FL.7 332 12 3.6% 1 +[T19L,T51I]-[T19I] FL.7 332 9 2.7% 1 +[T51I,H146K]-[H146Q] XBB.1.5.78 330 202 61.2% 0 (consensus) XBB.1.5.78 330 21 6.4% 1 -[K417N] XBB.1.5.78 330 11 3.3% 1 +[T732I] XBB.1.5.78 330 5 1.5% 1 +[H146K]-[H146Q] XBB.1.5.78 330 5 1.5% 1 +[T478R]-[T478K] EE.5 330 184 55.8% 0 +[H69-,V70-,N185Y,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EE.5 330 58 17.6% 1 +[H69-,V70-,N185Y,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.5 330 34 10.3% 1 +[H69-,V70-,N185Y,V213G,Q321L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.5 330 9 2.7% 1 +[H69-,V70-,K147E,N185Y,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.5 330 7 2.1% 1 +[H69-,V70-,N185Y,V213G,G339D,K444T,L452R,F486V,D1163Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.336 329 166 50.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.336 329 101 30.7% 1 +[G75V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.336 329 4 1.2% 1 +[E1111Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.336 329 4 1.2% 2 +[K558N,K1149R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.336 329 3 0.9% 2 +[G72E,A1070S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.253 329 272 82.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.253 329 20 6.1% 1 +[S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.253 329 17 5.2% 1 +[W258L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.253 329 7 2.1% 1 +[R21K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.253 329 3 0.9% 2 +[S494P,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GJ.1.1 329 188 57.1% 0 +[K182N,A222V,D253G,P521S]-[G252V] (consensus) GJ.1.1 329 25 7.6% 1 +[K182N,A222V,D253G,P521S,T523S]-[G252V] GJ.1.1 329 21 6.4% 1 +[K182N,A222V,D253G,P521S,V1122L]-[G252V] GJ.1.1 329 9 2.7% 1 +[K182N,A222V,D253G,P521S,A879S]-[G252V] GJ.1.1 329 7 2.1% 3 +[K182N,A222V,G252-,+253G,P521S]-[G252V] C.1 328 250 76.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.1 328 8 2.4% 1 +[F643Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.1 328 4 1.2% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.1 328 3 0.9% 2 +[D80N,N556Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.1 328 3 0.9% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.448 327 158 48.3% 0 +[T719I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.448 327 134 41.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.448 327 6 1.8% 2 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.448 327 5 1.5% 2 +[F2L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.448 327 3 0.9% 2 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.14.6 327 268 82.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14.6 327 5 1.5% 1 +[N17K,H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.6 327 4 1.2% 1 +[Q52H,H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.6 327 4 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D936H,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.6 327 4 1.2% 3 +[H69-,V70-,V213G,G339D,R403K,V445A,L452R,F486V,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.160.26 326 238 73.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.26 326 33 10.1% 1 +[S810L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.26 326 24 7.4% 1 +[K1038R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.26 326 5 1.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.26 326 4 1.2% 1 +[Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36 326 105 32.2% 0 +[P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36 326 48 14.7% 2 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.36 326 27 8.3% 3 +[Q677H,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36 326 18 5.5% 3 +[S12F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36 326 17 5.2% 3 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HZ.2 326 130 39.9% 0 +[P521T] (consensus) HZ.2 326 49 15.0% 1 +[F157L,P521T] HZ.2 326 48 14.7% 1 +[I231V,P521T] HZ.2 326 17 5.2% 1 +[P521T,Q607K] HZ.2 326 14 4.3% 2 +[I231V,T478R,P521T]-[T478K] BA.2.51 325 167 51.4% 0 +[V213G,G339D,Q493R,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.51 325 54 16.6% 1 +[V213G,G339D,Q493R,T747I,A876S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.51 325 30 9.2% 4 +[V213G,G339D,Q493R,T747I]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.51 325 13 4.0% 1 +[V213G,G339D,Q493R,T747I,A879S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.51 325 10 3.1% 2 +[L5F,V213G,G339D,Q493R,T747I,A876S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.36.35 324 164 50.6% 0 +[L452R,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.35 324 61 18.8% 3 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.35 324 28 8.6% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.35 324 26 8.0% 1 +[L452R,E583D,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.35 324 6 1.9% 1 +[L452R,E583D,I584V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.9.6 324 226 69.8% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.6 324 33 10.2% 1 +[V213G,G339D,L452M,Q493R,Q836R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.6 324 11 3.4% 1 +[T29I,V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.6 324 9 2.8% 1 +[K147T,V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.6 324 6 1.9% 4 +[V213G,G339D,L452M,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.25 324 230 71.0% 0 +[E554K] (consensus) FL.25 324 8 2.5% 1 +[L5F,E554K] FL.25 324 6 1.9% 2 +[N185D,Q218R,E554K] FL.25 324 6 1.9% 1 +[E554K,M1229I] FL.25 324 5 1.5% 1 +[E554K]-[K417N] XBB.2.3.6 324 201 62.0% 0 +[D253G,P521S]-[G252V] (consensus) XBB.2.3.6 324 42 13.0% 1 +[D253G,P521S,G1124V]-[G252V] XBB.2.3.6 324 9 2.8% 1 +[D253G,V267L,P521S]-[G252V] XBB.2.3.6 324 7 2.2% 1 +[D253G,N481S,P521S]-[G252V] XBB.2.3.6 324 3 0.9% 2 +[D253G,T299I,P521S,G1124V]-[G252V] JN.1.4.7 323 163 50.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.4.7 323 49 15.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.7 323 17 5.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.7 323 6 1.9% 3 +[+16MPLF,+18V,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.7 323 5 1.5% 1 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] CG.1 323 242 74.9% 0 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CG.1 323 10 3.1% 1 +[F2L,H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CG.1 323 4 1.2% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] CG.1 323 4 1.2% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CG.1 323 4 1.2% 6 +[H69-,V70-,L84I,V213G,G339D,K444M,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.214.2 322 246 76.4% 0 +[+214TDR,Q414K,N450K,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.214.2 322 24 7.5% 1 +[M153I,+214TDR,Q414K,N450K,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.2 322 9 2.8% 1 +[L5F,+214TDR,Q414K,N450K,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.2 322 8 2.5% 3 +[Q414K,N450K,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.2 322 7 2.2% 1 +[+214TDR,Q414K,N450K,T716I,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.99 322 239 74.2% 0 (consensus) XBB.1.5.99 322 6 1.9% 1 -[G142D] XBB.1.5.99 322 5 1.6% 2 -[G142D,F486P] XBB.1.5.99 322 3 0.9% 1 -[K417N] XBB.1.5.99 322 3 0.9% 1 +[R567I] GY.1 320 212 66.2% 0 +[L84I,E180V,T478R]-[T478K] (consensus) GY.1 320 16 5.0% 2 +[L84I,E180V,L455F,F456L,T478R]-[T478K] GY.1 320 7 2.2% 1 +[L84I,E180V,T478R,A684V]-[T478K] GY.1 320 7 2.2% 3 +[L84I,E180V,L455F,F456L,A475V,T478R]-[T478K] GY.1 320 4 1.2% 1 +[Q14R,L84I,E180V,T478R]-[T478K] BA.1.6 320 268 83.8% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.6 320 8 2.5% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.6 320 5 1.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.6 320 4 1.2% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,V551I,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.6 320 2 0.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,F338L,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BQ.1.1.27 319 225 70.5% 0 +[H69-,V70-,G181R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.27 319 45 14.1% 1 +[H69-,V70-,G181R,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.27 319 4 1.3% 1 +[H69-,V70-,L176I,G181R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.27 319 4 1.3% 2 +[H69-,V70-,G181R,V213G,G339D,K444T,L452R,F486V,I1225V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.27 319 4 1.3% 4 +[H69-,V70-,G181R,V213G,G339D,K444T,L452R,F486V]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.30 319 286 89.7% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.30 319 5 1.6% 1 +[S98F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.30 319 5 1.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.30 319 5 1.6% 1 +[V213G,D253G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.30 319 2 0.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XBB.1.5.36 317 191 60.3% 0 (consensus) XBB.1.5.36 317 12 3.8% 1 +[L5F] XBB.1.5.36 317 8 2.5% 1 +[A264V] XBB.1.5.36 317 6 1.9% 1 +[G1124V] XBB.1.5.36 317 6 1.9% 1 +[L922F] B.1.1.204 316 182 57.6% 0 +[N658K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.204 316 89 28.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.204 316 18 5.7% 2 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.204 316 6 1.9% 3 +[L5F,H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.204 316 3 0.9% 2 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XDQ.1 315 189 60.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDQ.1 315 61 19.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDQ.1 315 7 2.2% 1 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDQ.1 315 6 1.9% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDQ.1 315 5 1.6% 1 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.304 315 109 34.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.304 315 60 19.0% 2 +[G1085A]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.304 315 48 15.2% 1 -[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.304 315 36 11.4% 2 +[Q675H]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.304 315 17 5.4% 2 +[S247N]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.413 315 292 92.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.413 315 3 1.0% 1 +[Q321L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.413 315 1 0.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.413 315 1 0.3% 1 +[R682W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.413 315 1 0.3% 1 +[M153V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.38.1 315 178 56.5% 0 +[V213G,+246N,Y248-,G339D,K417T,K444N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.38.1 315 24 7.6% 1 +[V213G,+246N,Y248-,G339D,K417T,K444N,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38.1 315 22 7.0% 4 +[V213G,+246N,Y248-,G339D,K417T,K444N,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38.1 315 14 4.4% 1 +[V213G,+246N,Y248-,G339D,K417T,K444N,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38.1 315 8 2.5% 5 +[V213G,+246N,Y248-,G339D,K417T,K444N]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] FV.1 314 213 67.8% 0 +[K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,E484A,F486P,F490S] (consensus) FV.1 314 31 9.9% 1 +[K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,E484A,F486P,F490S] FV.1 314 5 1.6% 1 +[K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,D614S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,E484A,F486P,F490S,D614G] FV.1 314 4 1.3% 2 +[K147N,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,E484A,F486P,F490S] FV.1 314 3 1.0% 2 +[K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,D614S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,E484A,F486P,F490S,D614G] BT.1 314 231 73.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BT.1 314 13 4.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BT.1 314 10 3.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BT.1 314 7 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A706S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BT.1 314 5 1.6% 1 +[H69-,V70-,K150E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AW.1 313 224 71.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AW.1 313 49 15.7% 2 +[A222V,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AW.1 313 28 8.9% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AW.1 313 4 1.3% 1 +[N30S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AW.1 313 3 1.0% 1 +[C1240F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.56 313 198 63.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.56 313 14 4.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,H1101Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.56 313 13 4.2% 1 +[H69-,V70-,M177L,V213G,G339D,K444T,L452R,F486V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.56 313 6 1.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.56 313 4 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,H1101Y]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.303 313 255 81.5% 0 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.303 313 11 3.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.303 313 9 2.9% 1 +[T323I,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.303 313 8 2.6% 1 +[T29I,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.303 313 6 1.9% 1 +[A688V,V1065L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.471 312 195 62.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.471 312 44 14.1% 1 +[G769R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.471 312 7 2.2% 1 +[F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.471 312 6 1.9% 1 +[Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.471 312 4 1.3% 1 +[I1115V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.19 312 242 77.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.19 312 16 5.1% 1 +[G181V,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.19 312 11 3.5% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.19 312 5 1.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BA.2.19 312 5 1.6% 1 +[V213G,G339D,Q493R,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.43 312 185 59.3% 0 +[V213G,G339D,S371Y,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.43 312 71 22.8% 1 +[V213G,G339D,S371Y,Q493R,E1202Q]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] BA.2.43 312 13 4.2% 1 +[V213G,G339D,S371Y,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.43 312 7 2.2% 1 +[V213G,Y269H,G339D,S371Y,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] BA.2.43 312 5 1.6% 4 +[V213G,G339D,S371Y,Q493R,E1202Q]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] DV.6.2 311 203 65.3% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.6.2 311 33 10.6% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,Q218R,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.6.2 311 12 3.9% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P,F490S] DV.6.2 311 7 2.3% 2 +[K147E,W152R,F157L,G181V,N185D,I210V,V213G,Q218R,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.6.2 311 7 2.3% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,A845S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBB.1.5.104 311 175 56.3% 0 +[K304Q] (consensus) XBB.1.5.104 311 28 9.0% 1 +[K304Q,S939F] XBB.1.5.104 311 15 4.8% 1 +[K304Q,A1078T] XBB.1.5.104 311 11 3.5% 1 +[H146K,K304Q]-[H146Q] XBB.1.5.104 311 6 1.9% 3 +[H146K,K304Q,V615I,A1078T]-[H146Q] B.1.258.22 309 223 72.2% 0 +[A67V,H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.22 309 51 16.5% 1 +[P25T,A67V,H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.22 309 20 6.5% 1 +[L5F,A67V,H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.22 309 1 0.3% 2 +[L18F,A67V,H69-,V70-,N439K,L585F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.22 309 1 0.3% 1 +[A67V,H69-,V70-,T299A,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.2 308 138 44.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5.2 308 110 35.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.2 308 12 3.9% 1 +[T19R,S155I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.2 308 5 1.6% 1 +[T19R,E156G,F157-,R158-,G261D,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.2 308 3 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,M1233L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.15 307 233 75.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.15 307 12 3.9% 1 +[T19R,E156G,F157-,R158-,A372P,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.15 307 12 3.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.15 307 9 2.9% 2 +[T19R,E156G,F157-,R158-,A372P,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.15 307 6 2.0% 3 +[T19R,E156G,F157-,R158-,A372P,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.28 306 241 78.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.28 306 6 2.0% 4 +[K147E,W152R,F157L,F186L,I210V,V213G,G257S,R403K,K444T,L452R,F486S,A852V,S1147L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.28 306 6 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,T478R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,F486P,F490S] CH.1.1.28 306 5 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P521T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.28 306 4 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BF.31 306 148 48.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.31 306 65 21.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.31 306 13 4.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.31 306 10 3.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.31 306 6 2.0% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] JN.1.11.1 306 169 55.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.11.1 306 25 8.2% 1 +[+16IPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.11.1 306 22 7.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.11.1 306 12 3.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.11.1 306 4 1.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] CP.7 306 275 89.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N703Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.7 306 13 4.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N703Y,A1070V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.7 306 3 1.0% 1 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V,N703Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.7 306 2 0.7% 1 +[H69-,V70-,V213G,G261D,G339D,L452R,F486V,N703Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.7 306 2 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,N703Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.575.1 305 254 83.3% 0 +[S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.575.1 305 13 4.3% 1 +[S494P,T716I,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575.1 305 4 1.3% 1 +[L5F,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575.1 305 4 1.3% 1 +[L18F,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575.1 305 4 1.3% 1 +[A260S,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.16.1 305 143 46.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.16.1 305 67 22.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.16.1 305 47 15.4% 2 +[T19R,G75V,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.16.1 305 8 2.6% 1 +[T19R,G75V,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.16.1 305 6 2.0% 2 +[T19R,E156G,F157-,R158-,L452R,V615I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CV.1 305 206 67.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CV.1 305 19 6.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,A575S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CV.1 305 16 5.2% 1 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CV.1 305 8 2.6% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,A263T,L452R,F486S,A575S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CV.1 305 4 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,I569V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBM 305 267 87.5% 0 +[V213G,Y248N,G339D,L452R,F486V,T547I,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XBM 305 15 4.9% 3 +[V213G,Y248N,P251S,G339D,L452R,L455F,F486V,T547I,A1020S,Q1180K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBM 305 5 1.6% 4 +[V213G,Y248N,G339D,L452R,F486V,T547I,A1020S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBM 305 3 1.0% 1 +[V213G,Y248N,G339D,K444R,L452R,F486V,T547I,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBM 305 2 0.7% 1 +[S98F,V213G,Y248N,G339D,L452R,F486V,T547I,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.1.17 303 269 88.8% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.17 303 5 1.7% 1 +[P25T,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.17 303 4 1.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.17 303 2 0.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,A845S,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.17 303 2 0.7% 1 +[Q23K,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.1.329 302 195 64.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.329 302 45 14.9% 1 +[D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.329 302 14 4.6% 2 +[S254F,D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.329 302 9 3.0% 2 +[A871V,D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.329 302 7 2.3% 2 +[D839Y,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.2 302 129 42.7% 0 +[L141-,G142-,V143-,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2.5.2 302 22 7.3% 1 +[L141-,G142-,V143-,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.2 302 20 6.6% 4 +[L141-,G142-,V143-,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.2 302 14 4.6% 2 +[L141-,G142-,V143-,D215A,+215AGY,N440Y,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.2 302 11 3.6% 5 +[Q14-,C15-,V16-,N17-,L141-,G142-,V143-,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.31.1 302 181 59.9% 0 +[H69-,V70-,V213G,S247N,Y248-,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.31.1 302 38 12.6% 1 +[H69-,V70-,V213G,S247N,Y248-,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.31.1 302 24 7.9% 1 +[H69-,V70-,V213G,S247N,Y248-,G339D,L452R,F486V,A701V,A845S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.31.1 302 18 6.0% 1 +[H69-,V70-,V213G,S247N,Y248-,T274S,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.31.1 302 5 1.7% 1 +[H69-,V70-,V213G,S247N,Y248-,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] GV.1 302 136 45.0% 0 +[T478R]-[T478K] (consensus) GV.1 302 74 24.5% 2 +[Q218R,T478R,P521Q]-[T478K] GV.1 302 5 1.7% 1 +[T19L,T478R]-[T19I,T478K] GV.1 302 4 1.3% 1 +[T478R]-[G142D,T478K] GV.1 302 4 1.3% 1 +[T478R,S1249F]-[T478K] XBC.1.1 302 265 87.7% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.1 302 3 1.0% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I,L938F]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.1 302 2 0.7% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I,Q935E]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.1 302 2 0.7% 1 +[P25S,E156G,F157-,R158-,N185S,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.1 302 2 0.7% 2 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] BQ.1.1.55 302 268 88.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,K1149R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.55 302 5 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,N487S,K1149R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.55 302 4 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S810L,K1149R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.55 302 3 1.0% 1 +[H69-,V70-,T95I,V213G,G339D,K444T,L452R,F486V,K1149R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.55 302 2 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q787K,K1149R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.231 301 211 70.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.231 301 46 15.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.231 301 8 2.7% 1 +[P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.231 301 4 1.3% 1 +[V341I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.231 301 3 1.0% 1 +[S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] U.3 301 253 84.1% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) U.3 301 28 9.3% 1 +[L18F,K97N,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] U.3 301 13 4.3% 1 +[L18F,A222V,K1149M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] U.3 301 2 0.7% 2 +[L18F,K97N,A123V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] U.3 301 2 0.7% 1 +[L18F,P25L,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JL.1 301 228 75.7% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) JL.1 301 7 2.3% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,E773D,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JL.1 301 5 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,P809S,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JL.1 301 4 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,A1078V,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JL.1 301 4 1.3% 2 +[K147E,S151I,W152R,F157L,I210V,V213G,D215G,G257S,R346I,K444T,L452R,F486S,Q613H,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] B.1.177.53 301 228 75.7% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.53 301 18 6.0% 1 +[A67V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.53 301 12 4.0% 1 +[S98F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.53 301 8 2.7% 1 +[A222V,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.53 301 7 2.3% 1 +[A222V,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.4 301 158 52.5% 0 +[F486S,T883I]-[F486P] (consensus) XBB.1.4 301 27 9.0% 1 +[F486S,T883I]-[K417N,F486P] XBB.1.4 301 11 3.7% 1 +[F486S,T883I,E1188D]-[F486P] XBB.1.4 301 11 3.7% 1 +[F486S,T883I]-[G142D,F486P] XBB.1.4 301 7 2.3% 1 +[H146K,F486S,T883I]-[H146Q,F486P] B.1.1.4 301 274 91.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.4 301 6 2.0% 1 +[C1247F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.4 301 4 1.3% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.4 301 3 1.0% 1 +[R102I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.4 301 3 1.0% 1 +[T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.1 300 277 92.3% 0 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.221.1 300 4 1.3% 1 +[S98F,F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.1 300 2 0.7% 1 +[L54F,S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.1 300 2 0.7% 1 +[S98F,L821I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.1 300 2 0.7% 1 +[S98F,L1203F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.319 299 233 77.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.319 299 38 12.7% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.319 299 6 2.0% 2 +[T547I,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.319 299 4 1.3% 1 +[H1083R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.319 299 2 0.7% 7 +[P139-,F140-,L141-,G142-,V143-,Y145-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.417 298 276 92.6% 0 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.417 298 4 1.3% 1 +[D80Y,P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.417 298 3 1.0% 1 +[D80Y,C1236F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.417 298 3 1.0% 1 +[D80Y,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.417 298 1 0.3% 1 +[D80Y,L244S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.4 298 249 83.6% 0 +[H69-,V70-,R190T,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.4 298 9 3.0% 1 +[H69-,V70-,R190T,V213G,G339D,K444T,L452R,F486V,I1221V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.4 298 5 1.7% 1 +[H69-,V70-,H146-,R190T,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.4 298 3 1.0% 1 +[H69-,V70-,R190T,V213G,G339D,K444T,L452R,F486V,Q779R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.4 298 3 1.0% 1 +[H69-,V70-,R190T,V213G,G339D,K444T,L452R,F486V,N556K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] JJ.1 298 195 65.4% 0 +[Q52H,L455F,F456L] (consensus) JJ.1 298 20 6.7% 1 +[Q52H,H146K,L455F,F456L]-[H146Q] JJ.1 298 7 2.3% 1 +[T29I,Q52H,L455F,F456L] JJ.1 298 4 1.3% 1 +[Q52H,R102G,L455F,F456L] JJ.1 298 4 1.3% 1 +[Q52H,L455F,F456L,N481K] JN.1.21 298 101 33.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.21 298 38 12.8% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.21 298 36 12.1% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.21 298 16 5.4% 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.21 298 10 3.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDR 298 111 37.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDR 298 90 30.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDR 298 8 2.7% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,D796Y] XDR 298 8 2.7% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,A1174T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDR 298 6 2.0% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBB.1.16.5 298 220 73.8% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.5 298 13 4.4% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.5 298 5 1.7% 1 +[E180V,T478R]-[K417N,T478K] XBB.1.16.5 298 4 1.3% 1 +[E180V,T478R]-[R408S,T478K] XBB.1.16.5 298 4 1.3% 1 +[E180V,G181R,T478R]-[T478K] AY.95 297 173 58.2% 0 +[T19R,E156G,F157-,R158-,L244S,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.95 297 56 18.9% 1 +[T19R,E156G,F157-,R158-,L244S,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.95 297 8 2.7% 5 +[T19R,L244S,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.95 297 5 1.7% 1 +[T19R,E156G,F157-,R158-,L244S,L452R,T572I,P681R,D950N,V1189I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.95 297 3 1.0% 1 +[T19R,E156G,F157-,R158-,L244S,L452R,T572I,A647S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.425 297 277 93.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.425 297 5 1.7% 1 +[V483F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.425 297 3 1.0% 1 +[G75V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.425 297 1 0.3% 2 +[D80Y,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.425 297 1 0.3% 1 +[L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.22 296 118 39.9% 0 (consensus) XBB.1.22 296 47 15.9% 1 +[T883I] XBB.1.22 296 14 4.7% 1 +[T478R]-[T478K] XBB.1.22 296 12 4.1% 1 +[H146K]-[H146Q] XBB.1.22 296 11 3.7% 1 +[T259S] B.1.1.44 296 263 88.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.44 296 11 3.7% 1 +[T778I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.44 296 4 1.4% 1 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.44 296 4 1.4% 1 +[D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.44 296 3 1.0% 1 +[S689I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XCH 296 212 71.6% 0 +[L455F,F456L,S704L] (consensus) XCH 296 17 5.7% 1 +[H245Y,L455F,F456L,S704L] XCH 296 5 1.7% 1 +[L455F,F456L,E619K,S704L] XCH 296 5 1.7% 1 +[L455F,F456L,T478R,S704L]-[T478K] XCH 296 4 1.4% 1 +[T76I,L455F,F456L,S704L] DR.1 295 249 84.4% 0 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DR.1 295 11 3.7% 1 +[H69-,V70-,M153I,V213G,H245Y,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DR.1 295 6 2.0% 2 +[H69-,V70-,M153I,V213G,H245Y,G339D,K444T,L452R,F486V,N556K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DR.1 295 5 1.7% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DR.1 295 3 1.0% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] JN.1.47 295 235 79.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.47 295 6 2.0% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47 295 6 2.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47 295 3 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S813N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47 295 3 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] GW.5 295 101 34.2% 0 +[G184A,L455F,F456L,A475V,T478I,E554K]-[T478K] GW.5 295 71 24.1% 2 +[L455F,F456L,T478I,E554K]-[T478K] GW.5 295 7 2.4% 5 +[N185D,N450D,L455F,F456L,T478I,E554K,A845S]-[T478K] GW.5 295 6 2.0% 5 +[N185I,F186-,L368V,L455F,F456L,T478I,E554K]-[L368I,T478K] GW.5 295 5 1.7% 3 +[H146K,L455F,F456L,T478I,E554K]-[H146Q,T478K] B.1.258.3 295 251 85.1% 0 +[P25S,N439K,C1253F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.3 295 16 5.4% 3 +[N439K,Q690R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.3 295 6 2.0% 4 +[D215G,N439K,Q690R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.3 295 3 1.0% 1 +[N439K,C1253F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.3 295 2 0.7% 4 +[T20I,N439K,Q690R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.20.2 294 169 57.5% 0 +[Q52H,F456L,T478R]-[T478K] (consensus) FL.20.2 294 43 14.6% 1 +[Q52H,H146K,F456L,T478R]-[H146Q,T478K] FL.20.2 294 21 7.1% 1 +[Q52H,L452M,F456L,T478R]-[T478K] FL.20.2 294 8 2.7% 2 +[Q52H,L452M,F456L,T478R,L938I]-[T478K] FL.20.2 294 7 2.4% 1 +[Q52H,F456L,T478R]-[T19I,T478K] BA.2.3.5 294 233 79.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.5 294 15 5.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.5 294 9 3.1% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.5 294 3 1.0% 1 +[V213G,G339D,Q493R,A626V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.5 294 3 1.0% 1 +[V213G,G339D,Q493R,I931V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CA.1 293 242 82.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,T604I,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CA.1 293 10 3.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,T604I,D1199N,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.1 293 8 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,T604I,Y1155H,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.1 293 4 1.4% 1 +[K147E,W152R,F157L,G184S,I210V,V213G,G257S,L452R,F486S,T604I,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.1 293 3 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,T604I,A684V,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BQ.1.1.77 293 109 37.2% 0 +[H69-,V70-,F157S,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.77 293 108 36.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.77 293 17 5.8% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,D1084E]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.77 293 15 5.1% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T732I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.77 293 15 5.1% 2 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] GY.6 293 230 78.5% 0 +[E180V,T478R]-[T478K] (consensus) GY.6 293 5 1.7% 1 +[E180V,D215G,T478R]-[T478K] GY.6 293 5 1.7% 1 +[H146K,E180V,T478R]-[H146Q,T478K] GY.6 293 4 1.4% 1 +[E180V,F456L,T478R]-[T478K] GY.6 293 4 1.4% 2 +[A27-,E180V,T478R]-[L24-,A27S,T478K] BA.2.27 292 232 79.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.27 292 7 2.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.27 292 6 2.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.27 292 4 1.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N764K] BA.2.27 292 4 1.4% 2 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S,N764K] BA.2.86 291 147 50.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) BA.2.86 291 34 11.7% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86 291 7 2.4% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] BA.2.86 291 5 1.7% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86 291 5 1.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] B.1.1.286 291 245 84.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.286 291 25 8.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.286 291 6 2.1% 1 +[A647S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.286 291 4 1.4% 1 +[C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.286 291 3 1.0% 1 +[T76I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HW.1.1 290 189 65.2% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N460H,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) HW.1.1 290 19 6.6% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N460H,Q613H,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] HW.1.1 290 13 4.5% 1 +[P25S,T51S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N460H,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] HW.1.1 290 9 3.1% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,R346S,L452R,N460H,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] HW.1.1 290 9 3.1% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,A435S,L452R,N460H,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] AY.77 289 157 54.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.77 289 86 29.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.77 289 4 1.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.77 289 4 1.4% 2 +[L5F,T19R,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.77 289 4 1.4% 1 +[V3A,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.2.6 289 165 57.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.6 289 32 11.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A626S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.6 289 26 9.0% 1 +[K147E,W152R,F157L,I210V,V213G,R214L,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.6 289 8 2.8% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.6 289 7 2.4% 1 +[K147E,S151I,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.627 289 180 62.3% 0 +[W64R,M153T,A688V,S735A,T1027I,F1052Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.627 289 9 3.1% 1 +[W64R,M153T,E654Q,A688V,S735A,T1027I,F1052Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.627 289 5 1.7% 2 +[W64R,M153T,A688V,S735A,T1027I,F1052Y,E1258-,+1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.627 289 5 1.7% 1 +[W64R,M153T,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.627 289 5 1.7% 1 +[W64R,M153T,A688V,S735A,T1027I,F1052Y,E1258D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XAG 289 168 58.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAG 289 35 12.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] XAG 289 33 11.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAG 289 23 8.0% 1 +[V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAG 289 6 2.1% 1 +[V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.45 288 156 54.2% 0 +[V213G,G339D,Y449H,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.45 288 55 19.1% 1 +[L176F,V213G,G339D,Y449H,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.45 288 12 4.2% 1 +[V213G,G339D,Y449H,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.45 288 10 3.5% 1 +[S205F,V213G,G339D,Y449H,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.45 288 10 3.5% 1 +[L5F,V213G,G339D,Y449H,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.33 288 157 54.5% 0 +[K964E]-[T376A] (consensus) XBB.1.33 288 12 4.2% 1 +[K964E,T1117I]-[T376A] XBB.1.33 288 9 3.1% 1 +[L452R,K964E]-[T376A] XBB.1.33 288 8 2.8% 1 +[N354K,K964E]-[T376A] XBB.1.33 288 8 2.8% 2 +[N481K,S494P,K964E]-[T376A] XBC.1.6.1 287 220 76.7% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.6.1 287 12 4.2% 2 +[P25S,A67S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.1 287 10 3.5% 1 +[P25S,A67S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.1 287 6 2.1% 1 +[P25S,I101M,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.1 287 4 1.4% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] BU.3 287 229 79.8% 0 +[H69-,V70-,K147N,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BU.3 287 12 4.2% 2 +[H69-,V70-,K147N,V213G,G339D,N450D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BU.3 287 9 3.1% 1 +[H69-,V70-,K147N,V213G,G339D,N450D,L452R,F486V,G1124V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BU.3 287 8 2.8% 1 +[H69-,V70-,K147N,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BU.3 287 7 2.4% 1 +[H69-,V70-,K147N,V213G,G339D,N450D,L452R,F486V,Q954Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,Q954H] CL.1.1 287 222 77.4% 0 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CL.1.1 287 15 5.2% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] CL.1.1 287 4 1.4% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V,P1162L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CL.1.1 287 4 1.4% 1 +[H69-,V70-,K150E,V213G,G339D,R346G,K444N,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CL.1.1 287 4 1.4% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V,T549I,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] GL.1 286 160 55.9% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,D420N,G446D,L452R,P621S,A706V,T1117I,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] (consensus) GL.1 286 18 6.3% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,D420N,G446D,L452R,P621S,A706V,E748Q,T1117I,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] GL.1 286 15 5.2% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,T307I,G339D,D420N,G446D,L452R,P621S,A706V,T1117I,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] GL.1 286 13 4.5% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,D420N,G446D,L452R,P621S,A706V,T1117I,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] GL.1 286 6 2.1% 2 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,D420N,G446D,L452R,N481S,G482-,P621S,A706V,T1117I,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] B.1.503 286 252 88.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.503 286 5 1.7% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.503 286 3 1.0% 2 +[G72R,T299I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.503 286 3 1.0% 1 +[C1248R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.503 286 2 0.7% 1 +[L922F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DJ.1.1.1 286 158 55.2% 0 +[H69-,V70-,K147N,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) DJ.1.1.1 286 51 17.8% 1 +[H69-,V70-,K147N,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DJ.1.1.1 286 21 7.3% 1 +[H69-,V70-,K147N,V213G,G339D,K444N,L452R,F486A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DJ.1.1.1 286 10 3.5% 1 +[L5F,H69-,V70-,K147N,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DJ.1.1.1 286 5 1.7% 2 +[L5F,H69-,V70-,K147N,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] B.1.505 285 251 88.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.505 285 16 5.6% 1 +[R1091L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.505 285 2 0.7% 1 +[K1205N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.505 285 2 0.7% 1 +[T761I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.505 285 1 0.4% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GA.4.1 285 120 42.1% 0 +[D215H,H245Y,K356T,T478R,E554K,S704L]-[T478K] (consensus) GA.4.1 285 36 12.6% 1 +[D215H,H245Y,K356T,T478R,E554K,S704L,V1228L]-[T478K] GA.4.1 285 13 4.6% 1 +[H146K,D215H,H245Y,K356T,T478R,E554K,S704L]-[H146Q,T478K] GA.4.1 285 8 2.8% 2 +[N185I,F186-,D215H,H245Y,K356T,T478R,E554K,S704L]-[T478K] GA.4.1 285 7 2.5% 1 +[L54F,D215H,H245Y,K356T,T478R,E554K,S704L]-[T478K] FY.6 284 93 32.7% 0 +[Y200C] (consensus) FY.6 284 52 18.3% 1 +[Y200C,S939F] FY.6 284 30 10.6% 5 +[Y200C,+247LQGNS] FY.6 284 21 7.4% 1 +[Y200C,R408N]-[R408S] FY.6 284 8 2.8% 2 +[Y200C,S939F,P1162S] BA.2.31.1 284 151 53.2% 0 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.31.1 284 59 20.8% 1 +[L5F,I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.31.1 284 20 7.0% 1 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.31.1 284 8 2.8% 1 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.31.1 284 6 2.1% 1 +[I68T,K147N,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.37 283 169 59.7% 0 +[H69-,V70-,V213G,Y248S,+248AED,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.37 283 13 4.6% 4 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.37 283 11 3.9% 1 +[H69-,V70-,T95N,V213G,Y248S,+248AED,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.37 283 9 3.2% 5 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,R683W]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.37 283 5 1.8% 1 +[H69-,V70-,V213G,Y248S,+248AED,G339D,K444T,L452R,F486V,E554K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.43.7 283 138 48.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,S939F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.7 283 64 22.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,S939F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.7 283 24 8.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.7 283 13 4.6% 1 +[T19R,T33I,E156G,F157-,R158-,L452R,P681R,S939F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.7 283 8 2.8% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.29 283 180 63.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.29 283 62 21.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.29 283 8 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.29 283 8 2.8% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,T1120I,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.29 283 5 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.3 283 232 82.0% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.3 283 16 5.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.1.3 283 9 3.2% 1 +[V3G,H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.3 283 5 1.8% 1 +[V3G,H49Y,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.3 283 4 1.4% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.332 282 246 87.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.332 282 5 1.8% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.332 282 4 1.4% 1 +[D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.332 282 3 1.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.332 282 3 1.1% 1 +[I1210V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.4 282 229 81.2% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,V597I,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.4 282 22 7.8% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,Q1201K]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.4 282 5 1.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,V597I,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.4 282 4 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,V597I,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.4 282 2 0.7% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,V597I,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,S477N,T478K,E484A,F486P,F490S] XBB.1.5.55 282 179 63.5% 0 (consensus) XBB.1.5.55 282 18 6.4% 1 +[H146K]-[H146Q] XBB.1.5.55 282 17 6.0% 1 +[D253E] XBB.1.5.55 282 8 2.8% 1 +[L5F] XBB.1.5.55 282 5 1.8% 1 +[G485S] XBB.1.5.56 282 163 57.8% 0 +[A852S] (consensus) XBB.1.5.56 282 16 5.7% 2 +[N148T,T678I,A852S] XBB.1.5.56 282 12 4.3% 1 +[V433I,A852S] XBB.1.5.56 282 12 4.3% 1 +[A852S,T883I] XBB.1.5.56 282 10 3.5% 1 +[A852S,V1264L] B.1.177.72 281 250 89.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.72 281 7 2.5% 1 +[H49Y,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.72 281 3 1.1% 1 +[A222V,A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.72 281 3 1.1% 1 +[A222V,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.72 281 1 0.4% 1 +[A222V,V635A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.3 281 196 69.8% 0 +[K147E,W152R,F157L,I210V,V213G,+254P,G257-,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.3 281 11 3.9% 1 +[K147E,W152R,F157L,I210V,V213G,+254P,G257-,K444T,L452R,F486S,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.3 281 9 3.2% 1 +[K147E,W152R,F157L,I210V,V213G,+254P,G257-,K444T,L452R,F486S,P812S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.3 281 6 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,H245N,+254P,G257-,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.3 281 5 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,+254P,G257-,K444T,L452R,F486S,N657D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.384 281 264 94.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.384 281 11 3.9% 1 +[N1187Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.384 281 2 0.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.384 281 1 0.4% 1 +[Q1201K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.384 281 1 0.4% 1 +[G1167R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EK.2 281 233 82.9% 0 +[T259I] (consensus) EK.2 281 5 1.8% 1 +[T259I,T385I] EK.2 281 5 1.8% 1 +[T259I,S940F] EK.2 281 4 1.4% 1 +[T259I]-[Y144-] EK.2 281 3 1.1% 1 +[T259I,N481S] XBB.1.16.22 279 210 75.3% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.22 279 6 2.2% 1 +[E180V,T478R]-[K417N,T478K] XBB.1.16.22 279 5 1.8% 1 +[E180V,A411S,T478R]-[T478K] XBB.1.16.22 279 5 1.8% 1 +[E180V,T478R,V551I]-[T478K] XBB.1.16.22 279 3 1.1% 1 +[E180V,T478R]-[Y144-,T478K] FL.22 278 137 49.3% 0 (consensus) FL.22 278 53 19.1% 1 +[S247N] FL.22 278 9 3.2% 1 +[F186L] FL.22 278 7 2.5% 1 -[G142D] FL.22 278 6 2.2% 1 -[K417N] B.1.1.83 276 260 94.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.83 276 3 1.1% 1 +[A570V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.83 276 2 0.7% 1 +[V615F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.83 276 2 0.7% 1 +[L752I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.83 276 1 0.4% 1 +[E1092V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.13.2 275 103 37.5% 0 +[K356T] (consensus) FL.13.2 275 65 23.6% 1 +[D178H,K356T] FL.13.2 275 11 4.0% 1 +[Q14R,K356T] FL.13.2 275 10 3.6% 1 +[F306L,K356T] FL.13.2 275 8 2.9% 2 +[G75R,K356T,G1124V] CY.2 275 249 90.5% 0 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V,T1066N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CY.2 275 9 3.3% 1 +[H69-,V70-,V213G,D287N,G339D,K444M,L452R,F486V,T1066N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CY.2 275 3 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,K444M,L452R,F486V,T1066N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CY.2 275 3 1.1% 1 +[D53N,H69-,V70-,V213G,G339D,K444M,L452R,F486V,T1066N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CY.2 275 2 0.7% 1 +[H69-,V70-,V213G,D215Y,G339D,K444M,L452R,F486V,T1066N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] HS.1 274 138 50.4% 0 +[T478R]-[T478K] (consensus) HS.1 274 32 11.7% 1 +[T478R,E554K]-[T478K] HS.1 274 12 4.4% 1 +[T478R,A522P]-[T478K] HS.1 274 9 3.3% 1 +[T478R,I726V]-[T478K] HS.1 274 7 2.6% 1 +[F456L,T478R]-[T478K] B.1.160.28 274 214 78.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.28 274 13 4.7% 1 +[A575S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.28 274 10 3.6% 2 +[A575S,D1127G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.28 274 7 2.6% 2 +[T95I,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.28 274 6 2.2% 1 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.26.1 274 219 79.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.26.1 274 13 4.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,K1205R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.26.1 274 11 4.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,N764R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N764K] BQ.1.26.1 274 7 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.26.1 274 6 2.2% 1 +[H69-,V70-,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.1.398 274 141 51.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.398 274 18 6.6% 1 +[R214H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.398 274 15 5.5% 1 +[S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.398 274 15 5.5% 1 +[Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.398 274 9 3.3% 2 +[D80Y,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EA.1 274 84 30.7% 0 +[H69-,V70-,V213G,Y248S,+248KW,+249DL,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EA.1 274 51 18.6% 5 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EA.1 274 24 8.8% 1 +[H69-,V70-,V213G,Y248S,+248KW,+249DL,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EA.1 274 9 3.3% 6 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EA.1 274 6 2.2% 6 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] A.28 273 202 74.0% 0 +[H69-,V70-,N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.28 273 21 7.7% 1 +[H69-,V70-,N501T,A570V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] A.28 273 5 1.8% 1 +[H69-,V70-,N501T,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] A.28 273 4 1.5% 1 +[V6F,H69-,V70-,N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] A.28 273 3 1.1% 1 +[H69-,V70-,E281V,N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] AM.4 273 250 91.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AM.4 273 3 1.1% 1 +[L1024F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AM.4 273 2 0.7% 1 +[D820E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AM.4 273 2 0.7% 2 +[P681L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AM.4 273 2 0.7% 1 +[A1016V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.41 272 146 53.7% 0 +[A222V,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.41 272 87 32.0% 1 +[A222V,A899S,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.41 272 9 3.3% 1 +[A222V,D253A,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.41 272 4 1.5% 1 +[R102I,A222V,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.41 272 4 1.5% 1 +[T33I,A222V,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.58 272 201 73.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I934V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.58 272 12 4.4% 1 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V,I934V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.58 272 5 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I934V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.58 272 4 1.5% 1 +[H69-,V70-,G181A,V213G,G339D,K444T,L452R,F486V,I934V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.58 272 3 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I934V,G1167V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBZ 271 240 88.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) XBZ 271 6 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A771S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBZ 271 5 1.8% 1 +[H69-,V70-,D88G,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBZ 271 5 1.8% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBZ 271 4 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] B.1.142 270 178 65.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.142 270 56 20.7% 2 +[P479S,F1121L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.142 270 11 4.1% 2 +[V213L,F1121L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.142 270 7 2.6% 1 +[V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.142 270 5 1.9% 1 +[F1121L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XM 269 201 74.7% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XM 269 9 3.3% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XM 269 6 2.2% 2 +[M153I,V213G,G339D,Q493R,V1264M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XM 269 5 1.9% 18 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XM 269 4 1.5% 1 +[V213G,G339D,Q493R,K1255N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.305 269 219 81.4% 0 +[L54F,A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.305 269 7 2.6% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.305 269 7 2.6% 1 +[L54F,A520S,T1076I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.305 269 4 1.5% 1 +[L54F,A520S,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.305 269 3 1.1% 1 +[L54F,M177I,A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.351 269 112 41.6% 0 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.351 269 44 16.4% 2 +[L54F,A520S,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.351 269 26 9.7% 3 +[A520S,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.351 269 20 7.4% 1 +[L54F,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.351 269 14 5.2% 2 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] CK.2 268 174 64.9% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.2 268 19 7.1% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2 268 16 6.0% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,A1020T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2 268 9 3.4% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,S1147L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2 268 6 2.2% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.63 268 237 88.4% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.63 268 14 5.2% 1 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.63 268 7 2.6% 1 +[L18F,A222V,V539I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.63 268 2 0.7% 1 +[L18F,A222V,P499R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.63 268 2 0.7% 1 +[L5F,L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.17 268 202 75.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.17 268 8 3.0% 1 +[V213G,G339D,Q493R,P812S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.17 268 4 1.5% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.17 268 4 1.5% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.17 268 4 1.5% 1 +[V213G,G339D,Q493R,S1147L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] P.1.9 268 214 79.9% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,Q675H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.9 268 8 3.0% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,Q675H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.9 268 4 1.5% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,Q675H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.9 268 4 1.5% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T547I,Q675H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.9 268 2 0.7% 2 +[L18F,T20N,P26S,D138Y,R190S,E484K,N556K,Q675H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.433 267 187 70.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.433 267 15 5.6% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.433 267 11 4.1% 1 +[Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.433 267 6 2.2% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.433 267 5 1.9% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.13 267 259 97.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.13 267 1 0.4% 1 +[H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.13 267 1 0.4% 1 +[D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.13 267 1 0.4% 1 +[T676S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.13 267 1 0.4% 1 +[L585F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.470 266 58 21.8% 0 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.470 266 55 20.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.470 266 26 9.8% 1 +[D215Y,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.470 266 14 5.3% 3 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.470 266 11 4.1% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XAF 266 184 69.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAF 266 15 5.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] XAF 266 8 3.0% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAF 266 5 1.9% 1 +[V213G,G339D,Q493R,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAF 266 5 1.9% 5 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.4.1.10 265 202 76.2% 0 +[V3G,H69-,V70-,V213G,G339D,N354D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.10 265 17 6.4% 1 +[V3G,H69-,V70-,V213G,G339D,N354D,L452R,F486V,P1263R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.10 265 13 4.9% 1 +[V3G,H69-,V70-,V213G,G339D,N354D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.10 265 6 2.3% 1 +[H69-,V70-,V213G,G339D,N354D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.10 265 4 1.5% 2 +[V3G,H69-,V70-,V213G,G339D,N354D,L452R,F486V,P1263R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BR.5.1 265 197 74.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BR.5.1 265 8 3.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,D574V,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.5.1 265 6 2.3% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.5.1 265 3 1.1% 1 +[K147E,W152R,M153I,F157L,I210V,V213G,G257S,K444T,L452R,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.5.1 265 3 1.1% 2 +[K147E,W152R,F157L,I210A,V213G,G257S,K444T,L452R,L517F,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] XBB.1.41.2 265 199 75.1% 0 +[L335S,R403K,S494P] (consensus) XBB.1.41.2 265 7 2.6% 1 +[P251S,L335S,R403K,S494P] XBB.1.41.2 265 4 1.5% 1 +[L5F,L335S,R403K,S494P] XBB.1.41.2 265 4 1.5% 1 +[M177K,L335S,R403K,S494P] XBB.1.41.2 265 3 1.1% 1 +[V159I,L335S,R403K,S494P] B.1.1.228 264 116 43.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.228 264 52 19.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.228 264 40 15.2% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.228 264 15 5.7% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,N764K,D796Y,Q954H,N969K] B.1.1.228 264 11 4.2% 3 +[A243V,E554D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] CE.1 264 200 75.8% 0 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CE.1 264 10 3.8% 1 +[H69-,V70-,V213G,I312V,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CE.1 264 5 1.9% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CE.1 264 4 1.5% 1 +[H69-,V70-,V213G,V308L,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CE.1 264 4 1.5% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] GJ.3 264 152 57.6% 0 +[K182N,D253G,P521S]-[G252V] (consensus) GJ.3 264 8 3.0% 1 +[Q173R,K182N,D253G,P521S]-[G252V] GJ.3 264 8 3.0% 1 +[K182N,D253G,A348S,P521S]-[G252V] GJ.3 264 8 3.0% 2 +[Q173R,K182N,D253G,T478R,P521S]-[G252V,T478K] GJ.3 264 6 2.3% 2 +[K182N,A222V,D253G,A348S,P521S]-[G252V] B.1.160.14 263 210 79.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.14 263 13 4.9% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.14 263 7 2.7% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.14 263 6 2.3% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.14 263 3 1.1% 1 +[L1200F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.21 263 178 67.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.21 263 46 17.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.21 263 6 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.21 263 5 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.21 263 4 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,I818V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EM.1 262 211 80.5% 0 +[R214L] (consensus) EM.1 262 5 1.9% 2 +[T73I,R214L,V860I] EM.1 262 4 1.5% 1 +[R214L,K1045R] EM.1 262 4 1.5% 1 +[R214L,T1066A] EM.1 262 4 1.5% 1 +[H146K,R214L]-[H146Q] B.1.1.54 262 210 80.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.54 262 7 2.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.54 262 6 2.3% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.54 262 3 1.1% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.54 262 3 1.1% 1 +[M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.14 260 174 66.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.14 260 7 2.7% 2 +[V382L,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.14 260 6 2.3% 1 +[E1150K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.14 260 6 2.3% 1 +[Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.14 260 5 1.9% 1 +[I197V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.429 260 158 60.8% 0 +[E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.429 260 60 23.1% 1 +[E96D,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.429 260 13 5.0% 2 +[E96D,D614S,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.429 260 7 2.7% 2 +[D215H,T1027S,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.429 260 2 0.8% 1 +[T299I,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CA.3.1 260 189 72.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CA.3.1 260 46 17.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S,I834L,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.3.1 260 3 1.2% 1 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.3.1 260 3 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S,V622L,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.3.1 260 3 1.2% 2 +[K147E,N149S,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S,D936Y,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EG.5.1.5 259 167 64.5% 0 +[Q52H,F456L] (consensus) EG.5.1.5 259 14 5.4% 1 +[Q52H,F456L,H1101Y] EG.5.1.5 259 7 2.7% 1 +[Q52H,N354K,F456L] EG.5.1.5 259 4 1.5% 2 +[Q52H,F456L,V642I,G1171D] EG.5.1.5 259 3 1.2% 1 +[Q52H,F456L]-[Y144-] B.39 259 239 92.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.39 259 4 1.5% 1 +[R78K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.39 259 3 1.2% 2 +[D111N,T791I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.39 259 2 0.8% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.39 259 2 0.8% 1 +[L849F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GJ.1.2.2 259 157 60.6% 0 +[K182N,D253G,T478R,P521S]-[G252V,T478K] (consensus) GJ.1.2.2 259 12 4.6% 1 +[K182N,D253G,T478R,P521S,E654Q]-[G252V,T478K] GJ.1.2.2 259 8 3.1% 1 +[L176F,K182N,D253G,T478R,P521S]-[G252V,T478K] GJ.1.2.2 259 5 1.9% 1 +[K182N,D253G,T478R,P521S,T883I]-[G252V,T478K] GJ.1.2.2 259 4 1.5% 1 +[K182N,D253G,T478R,P521S]-[G252V,K417N,T478K] JN.1.3 258 156 60.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.3 258 32 12.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.3 258 9 3.5% 6 +[R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.3 258 8 3.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.3 258 5 1.9% 1 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.255 256 232 90.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.255 256 4 1.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.255 256 4 1.6% 1 +[A845V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.255 256 4 1.6% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.255 256 3 1.2% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.7 255 188 73.7% 0 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.7 255 5 2.0% 1 +[D936H,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.7 255 4 1.6% 1 +[A1026S,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.7 255 4 1.6% 1 +[A1078S,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.7 255 4 1.6% 1 +[L5F,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DV.8 255 180 70.6% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.8 255 31 12.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,A701S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.8 255 11 4.3% 2 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,V445A,L452R,F486S,Q613H,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.8 255 9 3.5% 2 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,A701S,D1084Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.8 255 3 1.2% 1 +[K147E,W152R,F157L,K182T,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BB.2 255 194 76.1% 0 +[T95I,+143T,Y144S,Y145N,R346K,E484K,S939F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) BB.2 255 19 7.5% 1 +[T95I,Y144S,Y145N,R346K,E484K,S939F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BB.2 255 13 5.1% 1 +[L5F,T95I,+143T,Y144S,Y145N,R346K,E484K,S939F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BB.2 255 4 1.6% 2 +[L5F,T95I,Y144S,Y145N,R346K,E484K,S939F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BB.2 255 3 1.2% 3 +[T95I,R346K,E484K,S939F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.612 255 141 55.3% 0 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.612 255 52 20.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.612 255 14 5.5% 1 +[L5F,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.612 255 8 3.1% 1 +[L5F,S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.612 255 7 2.7% 2 +[E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AH.3 255 102 40.0% 0 +[V3G,L5F,A352S,G842S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AH.3 255 95 37.3% 1 +[V3G,L5F,A352S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AH.3 255 10 3.9% 2 +[V3G,L5F,A352S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AH.3 255 10 3.9% 2 +[V3G,L5F,A352S,A1078V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AH.3 255 7 2.7% 2 +[A352S,G842S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.33 255 214 83.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.33 255 6 2.4% 2 +[A222V,P1263S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.33 255 5 2.0% 1 +[M177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.33 255 3 1.2% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.33 255 3 1.2% 1 +[Q957L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.13.1 255 202 79.2% 0 +[A411S] (consensus) FL.13.1 255 8 3.1% 3 +[A411S,L455F,F456L,D1259Y] FL.13.1 255 2 0.8% 1 +[A411S,T547I] FL.13.1 255 2 0.8% 1 +[H146K,A411S]-[H146Q] FL.13.1 255 2 0.8% 1 +[A411S]-[Y144-] BS.1.1 254 154 60.6% 0 +[V213N,+213GEG,G257V,G339D,K356T,L452R,G476-,T478N,+478K,S640F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] (consensus) BS.1.1 254 14 5.5% 2 +[L5F,G184V,V213N,+213GEG,G257V,G339D,K356T,L452R,G476-,T478N,+478K,S640F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] BS.1.1 254 8 3.1% 1 +[V213N,+213GEG,G339D,K356T,L452R,G476-,T478N,+478K,S640F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] BS.1.1 254 7 2.8% 4 +[V213G,G257V,G339D,K356T,L452R,G476-,T478N,+478K,S640F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] BS.1.1 254 5 2.0% 5 +[V213G,G257V,G339D,K356T,L452R,G476-,T478N,+478K,S640F,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] B.1.177.80 254 151 59.4% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.80 254 55 21.7% 1 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.80 254 20 7.9% 2 +[L18F,A222V,A623V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.80 254 15 5.9% 1 +[L5F,L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.80 254 3 1.2% 3 +[L18F,P26L,A222V,A260T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HH.2 254 133 52.4% 0 +[G184V,D253G,P521S]-[G252V] (consensus) HH.2 254 31 12.2% 1 +[G184V,D253G,T478R,P521S]-[G252V,T478K] HH.2 254 9 3.5% 1 +[H146K,G184V,D253G,P521S]-[H146Q,G252V] HH.2 254 7 2.8% 1 +[G184V,L212S,D253G,P521S]-[G252V] HH.2 254 6 2.4% 5 +[G184V,D253G,P521S]-[L24-,P25-,P26-,A27S,Y144-,G252V] AZ.4 253 216 85.4% 0 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AZ.4 253 20 7.9% 1 +[T95I,E484K,D796H,G1171S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.4 253 7 2.8% 1 +[T95I,E484K,V622F,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.4 253 3 1.2% 1 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.4 253 2 0.8% 1 +[T95I,E484K,D796H,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.124.1.1 253 63 24.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.124.1.1 253 43 17.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124.1.1 253 40 15.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124.1.1 253 23 9.1% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,I844V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124.1.1 253 22 8.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1127G]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.2 253 45 17.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.112.2 253 32 12.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P499R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.2 253 24 9.5% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P499R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.2 253 12 4.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.2 253 10 4.0% 2 +[T19R,E156G,F157-,R158-,L452R,E484Q,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.10.2 253 178 70.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T523N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.10.2 253 30 11.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T523N]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10.2 253 4 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T523N,A829T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10.2 253 4 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T523N,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10.2 253 3 1.2% 1 +[H49Y,H69-,V70-,V213G,G339D,K444T,L452R,F486V,T523N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.1.1.5 253 156 61.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.5 253 29 11.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.5 253 11 4.3% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.5 253 8 3.2% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,A694V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.5 253 6 2.4% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XBB.1.5.27 253 142 56.1% 0 +[T478R]-[T478K] (consensus) XBB.1.5.27 253 67 26.5% 1 +[S256L,T478R]-[T478K] XBB.1.5.27 253 10 4.0% 1 +[T478R,G946R]-[T478K] XBB.1.5.27 253 4 1.6% 2 +[L244F,H245-,T478R]-[T478K] XBB.1.5.27 253 3 1.2% 1 +[T478R,V642A]-[T478K] B.1.1.243 252 139 55.2% 0 +[V362F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.243 252 54 21.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.243 252 10 4.0% 2 +[M177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.243 252 7 2.8% 2 +[S659L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.243 252 4 1.6% 2 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99 252 107 42.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.99 252 57 22.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99 252 9 3.6% 2 +[E156G,F157-,R158-,L452R,P681R,D950N]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99 252 7 2.8% 2 +[T19R,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99 252 5 2.0% 1 +[T19R,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.289 251 228 90.8% 0 +[H245Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.289 251 11 4.4% 1 +[H245Y,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.289 251 2 0.8% 1 +[H245Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.289 251 2 0.8% 1 +[H245Y,V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.289 251 1 0.4% 1 +[S12C,H245Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.19.1 251 143 57.0% 0 +[E554K] (consensus) XBB.1.19.1 251 16 6.4% 3 +[L455F,F456L,T478I,E554K]-[T478K] XBB.1.19.1 251 10 4.0% 1 +[H146K,E554K]-[H146Q] XBB.1.19.1 251 7 2.8% 1 +[E554K,A653V] XBB.1.19.1 251 5 2.0% 1 +[V62L,E554K] B.1.1.368 250 118 47.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.368 250 31 12.4% 1 +[T385I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.368 250 24 9.6% 1 +[Q779K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.368 250 14 5.6% 1 +[A67V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.368 250 7 2.8% 1 +[W152L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.1 250 137 54.8% 0 +[N641S,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.36.1 250 68 27.2% 1 +[N641S,Q677H,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.1 250 16 6.4% 1 +[T51I,N641S,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.1 250 15 6.0% 1 +[L5F,N641S,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.1 250 5 2.0% 2 +[N641S,Q677H,C1243S,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.48 250 163 65.2% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.48 250 51 20.4% 1 +[L18F,A222V,S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.48 250 22 8.8% 1 +[L18F,A222V,I1130M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.48 250 3 1.2% 1 +[L18F,A222V,S359N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.48 250 2 0.8% 1 +[L5F,L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.8 250 219 87.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.8 250 4 1.6% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.8 250 4 1.6% 3 +[S640Y,N641-,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.8 250 4 1.6% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.8 250 2 0.8% 1 +[I1210V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BR.3 250 208 83.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BR.3 250 7 2.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,Y489H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.3 250 5 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,I472L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.3 250 3 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.3 250 3 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,E554Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.3.4 250 221 88.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.3.4 250 13 5.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.4 250 8 3.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.4 250 2 0.8% 4 +[T19R,A67V,H69-,V70-,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.4 250 1 0.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,I834F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.4 249 113 45.4% 0 +[V90I,K444R,F486S]-[G252V,F486P] (consensus) XBB.4 249 31 12.4% 1 +[K444R,F486S]-[G252V,F486P] XBB.4 249 14 5.6% 2 +[K444R,F486S,E990D]-[G252V,F486P] XBB.4 249 12 4.8% 2 +[K444R,F486S,L858I]-[G252V,F486P] XBB.4 249 12 4.8% 1 +[V90I,K444R,F486S]-[G252V,R408S,F486P] FL.13.3 248 182 73.4% 0 (consensus) FL.13.3 248 6 2.4% 1 +[V1264L] FL.13.3 248 5 2.0% 1 +[G1124V] FL.13.3 248 4 1.6% 1 +[E554G] FL.13.3 248 3 1.2% 1 +[A292S] BA.5.12 248 174 70.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.12 248 9 3.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.12 248 5 2.0% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,N679K,P681H] BA.5.12 248 5 2.0% 1 +[H69-,V70-,F140V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.12 248 4 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BF.7.5.1 247 175 70.9% 0 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.5.1 247 19 7.7% 3 +[H69-,V70-,G181V,L212F,V213G,G339D,L452R,F486V,D1084E]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,N460K,F486P,F490S] BF.7.5.1 247 7 2.8% 2 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.5.1 247 5 2.0% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BF.7.5.1 247 5 2.0% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.37 247 194 78.5% 0 +[H69-,V70-,Y145H,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.37 247 8 3.2% 2 +[H69-,V70-,Y145H,V213G,G339D,R346S,L452R,F486V,L1224F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.37 247 6 2.4% 1 +[H69-,V70-,Y145H,V213G,G339D,K356T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.37 247 4 1.6% 1 +[L5F,H69-,V70-,Y145H,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.37 247 3 1.2% 1 +[H69-,V70-,Y145H,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JD.1 247 133 53.8% 0 +[L455F,F456L] (consensus) JD.1 247 22 8.9% 1 +[T323I,L455F,F456L] JD.1 247 13 5.3% 1 +[L455F,F456L]-[R346T] JD.1 247 13 5.3% 2 +[L455F,F456L]-[R346T,K417N] JD.1 247 6 2.4% 1 +[L455F,F456L,P809T] AY.82 246 218 88.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.82 246 12 4.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.82 246 5 2.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.82 246 3 1.2% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,A1078S,E1195Q]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.82 246 2 0.8% 2 +[T19R,E156G,R158-,V159-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.21 246 149 60.6% 0 +[R190S,L452R,D614N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.21 246 16 6.5% 3 +[D614N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.21 246 12 4.9% 3 +[D614N,V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.21 246 7 2.8% 5 +[E96D,D614N,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.21 246 5 2.0% 1 +[R190S,D215G,L452R,D614N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.15 246 120 48.8% 0 +[K147E,W152R,F157L,K182N,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.15 246 33 13.4% 1 +[K147E,W152R,F157L,K182N,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.15 246 12 4.9% 3 +[K147E,W152R,F157L,S161T,K182N,I210V,V213G,G257S,L441F,K444T,L452R,F486S,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.15 246 10 4.1% 2 +[K147E,W152R,F157L,K182N,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P,F490S] CH.1.1.15 246 9 3.7% 2 +[K147E,W152R,F157L,K182N,I210V,V213G,K444T,L452R,F486S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.595.4 246 226 91.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.595.4 246 9 3.7% 1 +[M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.4 246 4 1.6% 1 +[L865F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.4 246 2 0.8% 2 +[D228Y,V911I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.4 246 2 0.8% 1 +[L821V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.59 245 214 87.3% 0 +[V213G,G339D,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.59 245 13 5.3% 1 +[V213G,G339D,Q493R,D1153Y,K1245N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.59 245 6 2.4% 1 +[L5F,V213G,G339D,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.59 245 2 0.8% 1 +[V213G,G339D,Q493R,A701V,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.59 245 2 0.8% 1 +[V213G,G339D,Q493R,I844S,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] GS.1 245 177 72.2% 0 +[V213D,D253G,T478R,P521S]-[V213E,G252V,T478K] (consensus) GS.1 245 8 3.3% 2 +[F157S,G184D,V213D,D253G,T478R,P521S]-[V213E,G252V,T478K] GS.1 245 8 3.3% 3 +[H146K,F157S,G184D,V213D,D253G,T478R,P521S]-[H146Q,V213E,G252V,T478K] GS.1 245 5 2.0% 1 +[T33A,V213D,D253G,T478R,P521S]-[V213E,G252V,T478K] GS.1 245 4 1.6% 3 +[T29I,V213D,D253G,T478R,P521S,T732I,E1150D]-[V213E,G252V,T478K] P.1.8 245 184 75.1% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,T470N,E484K,P681R,T1027I,V1176F,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.8 245 7 2.9% 1 +[L18F,T20N,P26S,R190S,K417T,T470N,E484K,P681R,T1027I,V1176F,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.8 245 5 2.0% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,T470N,E484K,P681R,T1027I,V1176F,C1235F,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.8 245 4 1.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,T470N,E484K,P681R,T1027I,V1176F,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.8 245 3 1.2% 1 +[L18F,T20N,P26S,D138Y,R190S,T259R,K417T,T470N,E484K,P681R,T1027I,V1176F,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.66 245 179 73.1% 0 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.66 245 16 6.5% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,S691F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.66 245 13 5.3% 1 +[H69-,V70-,K147N,I210-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.66 245 6 2.4% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,Q675-]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.66 245 3 1.2% 1 +[S12Y,H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EG.5.1.9 244 189 77.5% 0 +[Q52H,L176F,F456L] (consensus) EG.5.1.9 244 19 7.8% 1 +[Q52H,L176F,F456L,C1247F] EG.5.1.9 244 6 2.5% 1 +[Q52H,L176F,F456L]-[Y144-] EG.5.1.9 244 3 1.2% 1 +[Q52H,L176F,F456L,E1195Q] EG.5.1.9 244 2 0.8% 1 +[Q52H,L176F,+176F,F456L] BE.6 243 177 72.8% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.6 243 9 3.7% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.6 243 7 2.9% 1 +[H69-,V70-,H146Y,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.6 243 6 2.5% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,L1203F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.6 243 3 1.2% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,C1241F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.1.5 243 137 56.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.1.5 243 16 6.6% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.1.5 243 7 2.9% 1 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.1.5 243 6 2.5% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.1.5 243 5 2.1% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] BF.7.10 243 209 86.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.10 243 4 1.6% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,Q1201K]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.10 243 4 1.6% 2 +[H69-,V70-,R158S,V213G,D215E,G339D,L452R,F486V,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.10 243 4 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.10 243 4 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V642G,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] GH.1 243 195 80.2% 0 +[D253G,F486S,P521S]-[G252V,F486P] (consensus) GH.1 243 4 1.6% 1 +[D253G,F486S,P521S,K558N]-[G252V,F486P] GH.1 243 3 1.2% 2 +[H146K,D253G,F486S,P521S,L752F]-[H146Q,G252V,F486P] GH.1 243 3 1.2% 1 +[H146K,D253G,F486S,P521S]-[H146Q,G252V,F486P] GH.1 243 3 1.2% 1 +[D253G,F486S,P521S,K1266E]-[G252V,F486P] B.1.223 242 173 71.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.223 242 46 19.0% 1 +[L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.223 242 6 2.5% 1 +[N658Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.223 242 3 1.2% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.223 242 2 0.8% 2 +[L822F,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBL.3 242 146 60.3% 0 (consensus) XBL.3 242 15 6.2% 1 +[Y453H] XBL.3 242 8 3.3% 1 -[Y144-] XBL.3 242 7 2.9% 1 +[S98F] XBL.3 242 7 2.9% 1 +[R78M] BQ.1.26 241 179 74.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.26 241 11 4.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.26 241 5 2.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.26 241 5 2.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N679K] BQ.1.26 241 5 2.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A1070S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.1.38 241 169 70.1% 0 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.38 241 5 2.1% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,S494P,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.38 241 4 1.7% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.38 241 3 1.2% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,N603S,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.38 241 2 0.8% 1 +[H69-,V70-,K97E,V213G,P251L,G339D,K444T,L452R,F486V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.48 241 172 71.4% 0 +[H69-,V70-,V213G,H245N,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.48 241 17 7.1% 1 +[H69-,V70-,V213G,H245N,G339D,K444T,L452R,F486V,Q493L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.48 241 12 5.0% 1 +[H69-,V70-,V213G,H245N,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.48 241 3 1.2% 1 +[H69-,V70-,V213G,H245N,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,F486P,F490S] BQ.1.1.48 241 2 0.8% 1 +[H69-,V70-,V213G,H245N,G339D,K444T,L452R,A475S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.38 240 166 69.2% 0 +[I666V] (consensus) XBB.1.5.38 240 15 6.2% 1 +[H146K,I666V]-[H146Q] XBB.1.5.38 240 4 1.7% 1 +[E554K,I666V] XBB.1.5.38 240 4 1.7% 1 +[F456L,I666V] XBB.1.5.38 240 4 1.7% 1 +[I666V]-[R408S] JN.1.28 239 136 56.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.28 239 17 7.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,Q954L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H] JN.1.28 239 16 6.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.28 239 7 2.9% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,A575S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.28 239 5 2.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.408 239 70 29.3% 0 +[D936V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.408 239 60 25.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.408 239 45 18.8% 2 +[Q690H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.408 239 12 5.0% 2 -[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.408 239 7 2.9% 2 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.631 239 70 29.3% 0 +[L18R,T95I,R158S,L452M,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.631 239 37 15.5% 1 +[L18R,T95I,R158S,L176F,L452M,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.631 239 22 9.2% 2 +[L18R,T95I,R158S,L176F,A411S,L452M,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.631 239 11 4.6% 1 +[L18R,T95I,R158S,T307I,L452M,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.631 239 9 3.8% 1 +[L18R,T95I,R158S,L452M,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Z.1 239 211 88.3% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) Z.1 239 11 4.6% 1 +[P85S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Z.1 239 2 0.8% 1 +[A222V,P793S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Z.1 239 2 0.8% 1 +[A222V,Q564L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Z.1 239 2 0.8% 1 +[A222V,A831V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.38.1 238 205 86.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.38.1 238 20 8.4% 1 +[H69-,V70-,T76A,V213G,G339D,L452R,F486V,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38.1 238 2 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S640F,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38.1 238 2 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A871V,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38.1 238 1 0.4% 1 +[H69-,V70-,V213G,G261D,G339D,L452R,F486V,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] GJ.4 238 69 29.0% 0 +[M153I,K182N,D253G,P521S]-[G252V] (consensus) GJ.4 238 68 28.6% 1 +[M153I,K182N,D253G,P521S,S939F]-[G252V] GJ.4 238 18 7.6% 1 +[M153I,K182N,T208M,D253G,P521S]-[G252V] GJ.4 238 12 5.0% 1 +[A67V,M153I,K182N,D253G,P521S]-[G252V] GJ.4 238 5 2.1% 2 +[+149N,M153I,K182N,T208M,D253G,P521S]-[G252V] EY.1 238 113 47.5% 0 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EY.1 238 29 12.2% 1 +[H69-,V70-,F157L,V213G,P251L,G339D,K444T,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EY.1 238 20 8.4% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,Q613H,Q1180K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EY.1 238 8 3.4% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,Q613H,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EY.1 238 7 2.9% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.71 238 127 53.4% 0 +[V511I] (consensus) XBB.1.5.71 238 19 8.0% 2 +[V511I]-[G142D,K417N] XBB.1.5.71 238 7 2.9% 1 +[V511I]-[K417N] XBB.1.5.71 238 5 2.1% 1 +[H146K,V511I]-[H146Q] XBB.1.5.71 238 5 2.1% 1 +[V511I,L546I] XBB.1.11.1 237 160 67.5% 0 (consensus) XBB.1.11.1 237 17 7.2% 1 +[P426S] XBB.1.11.1 237 7 3.0% 1 +[E224Q] XBB.1.11.1 237 4 1.7% 1 +[T478N]-[T478K] XBB.1.11.1 237 3 1.3% 1 +[I1216V] JN.1.16.1 237 105 44.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.16.1 237 9 3.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.16.1 237 8 3.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.16.1 237 6 2.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] JN.1.16.1 237 6 2.5% 10 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] AY.102.2 236 131 55.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.102.2 236 12 5.1% 1 +[T19R,G72R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102.2 236 10 4.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1264A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102.2 236 9 3.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102.2 236 9 3.8% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1264A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.56 236 169 71.6% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.56 236 24 10.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.56 236 10 4.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.56 236 5 2.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,S680F,P681R,D950N,M1229V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.56 236 3 1.3% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.6.2 236 173 73.3% 0 +[T19L,D253G,F486S]-[T19I,G252V,F486P] (consensus) XBB.2.6.2 236 20 8.5% 1 +[D253G,F486S]-[G252V,F486P] XBB.2.6.2 236 7 3.0% 1 +[T19L,D253G,F486S]-[T19I,G252V,R408S,F486P] XBB.2.6.2 236 4 1.7% 1 +[T19L,H146K,D253G,F486S]-[T19I,H146Q,G252V,F486P] XBB.2.6.2 236 3 1.3% 1 +[T19L,D253G,F486S]-[T19I,Q183E,G252V,F486P] DS.2 236 156 66.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) DS.2 236 13 5.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T572I,E1258V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] DS.2 236 8 3.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F486S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] DS.2 236 6 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] DS.2 236 5 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E484V,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P] FE.1.1.1 236 163 69.1% 0 +[F456L] (consensus) FE.1.1.1 236 9 3.8% 1 +[F456L,H1058Y] FE.1.1.1 236 8 3.4% 1 +[F456L,P621S] FE.1.1.1 236 7 3.0% 1 +[F456L,P809L] FE.1.1.1 236 6 2.5% 2 +[F456L,I794T,H1058Y] XBB.1.5.94 236 158 66.9% 0 +[Q613H] (consensus) XBB.1.5.94 236 16 6.8% 1 +[D253G,Q613H] XBB.1.5.94 236 15 6.4% 1 +[T478R,Q613H]-[T478K] XBB.1.5.94 236 5 2.1% 1 +[A348T,Q613H] XBB.1.5.94 236 3 1.3% 2 +[T478R,Q613H,C1243F]-[T478K] A.5 235 203 86.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.5 235 9 3.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.5 235 6 2.6% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.5 235 2 0.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.5 235 2 0.9% 1 +[D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110 235 202 86.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.110 235 11 4.7% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110 235 7 3.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110 235 3 1.3% 1 +[D88N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110 235 3 1.3% 2 +[T286I,A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.4 235 222 94.5% 0 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.221.4 235 3 1.3% 1 +[S98F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.4 235 2 0.9% 1 +[S98F,G1167S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.4 235 2 0.9% 1 +[T20I,S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.4 235 1 0.4% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.385 235 186 79.1% 0 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.385 235 12 5.1% 1 +[Q675H,P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.385 235 6 2.6% 1 +[Q675H,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.385 235 4 1.7% 1 +[Q675H,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.385 235 3 1.3% 1 +[H49Y,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.7 235 190 80.9% 0 +[R403K,L513F] (consensus) EG.7 235 8 3.4% 1 +[H146K,R403K,L513F]-[H146Q] EG.7 235 6 2.6% 1 +[A243V,R403K,L513F] EG.7 235 3 1.3% 1 +[R403K,L513F,A647S] EG.7 235 2 0.9% 1 +[R403K,L513F]-[T19I] B.1.610 235 211 89.8% 0 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.610 235 12 5.1% 1 +[L18F,C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.610 235 3 1.3% 1 +[L18F,I68T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.610 235 1 0.4% 1 +[L18F,A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.610 235 1 0.4% 1 +[L18F,S205F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.3 234 207 88.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.3 234 7 3.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.3 234 6 2.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.3 234 4 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.3 234 2 0.9% 1 +[H49Y,H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.453 234 215 91.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.453 234 4 1.7% 1 +[A647S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.453 234 2 0.9% 1 +[I670M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.453 234 2 0.9% 1 +[P807L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.453 234 2 0.9% 1 +[A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.38.2 234 132 56.4% 0 +[H146-,F157S,V213G,G339D,K417T,K444N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.38.2 234 22 9.4% 2 +[F157S,V213G,G339D,K417T,K444N,Q493R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38.2 234 16 6.8% 1 +[F157S,V213G,G339D,K417T,K444N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38.2 234 9 3.8% 4 +[F157S,V213G,L244F,H245-,A264S,G339D,K417T,K444N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38.2 234 4 1.7% 2 +[F157S,V213G,G339D,K417T,K444N,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] AZ.5 234 145 62.0% 0 +[D80Y,T95I,W258L,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AZ.5 234 27 11.5% 1 +[D80Y,T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.5 234 26 11.1% 2 +[D80Y,T95I,A243S,W258L,E484K,D796H,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.5 234 11 4.7% 2 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.5 234 5 2.1% 1 +[D80Y,T95I,W258L,E484K,D796H,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.5.2.60 234 154 65.8% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.60 234 14 6.0% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] BA.5.2.60 234 9 3.8% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.60 234 6 2.6% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.60 234 4 1.7% 2 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N764K,D796Y] XBB.1.16.16 234 149 63.7% 0 +[E180V,T478R,Q613H]-[T478K] (consensus) XBB.1.16.16 234 11 4.7% 2 +[E180V,A222V,T478R,K529N,Q613H]-[T478K] XBB.1.16.16 234 9 3.8% 1 +[H69Y,E180V,T478R,Q613H]-[T478K] XBB.1.16.16 234 7 3.0% 1 +[Y28H,E180V,T478R,Q613H]-[T478K] XBB.1.16.16 234 4 1.7% 1 +[E180V,A222V,T478R,Q613H]-[T478K] FL.11 232 170 73.3% 0 (consensus) FL.11 232 15 6.5% 1 +[N481K] FL.11 232 5 2.2% 1 +[D215G] FL.11 232 3 1.3% 1 -[Y144-] FL.11 232 2 0.9% 1 +[T1006S] CM.5 232 167 72.0% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.5 232 18 7.8% 1 +[K150I,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.5 232 14 6.0% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,V445A,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.5 232 2 0.9% 3 +[M153T,N164K,V213G,H245N,G257D,G339D,N450D,L452M,E484R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,E484A,F486P,F490S] CM.5 232 2 0.9% 1 +[M153T,N164K,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBB.1.5.25 231 144 62.3% 0 +[K97T] (consensus) XBB.1.5.25 231 17 7.4% 1 +[K97T]-[R408S] XBB.1.5.25 231 6 2.6% 2 +[K97T,T323I]-[K417N] XBB.1.5.25 231 5 2.2% 1 +[K97T,D1118Y] XBB.1.5.25 231 4 1.7% 1 +[K97T,T478R]-[T478K] AY.131 230 66 28.7% 0 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,N501T,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.131 230 36 15.7% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,N501T,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.131 230 27 11.7% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,E484Q,N501T,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.131 230 16 7.0% 2 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,E484Q,N501T,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.131 230 8 3.5% 2 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,N501T,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.411 230 126 54.8% 0 +[H1159Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.411 230 11 4.8% 1 +[T676A,H1159Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.411 230 8 3.5% 2 +[A684V,H1159Y,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.411 230 6 2.6% 1 +[A684V,H1159Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.411 230 6 2.6% 1 +[T33S,H1159Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.50 230 176 76.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.50 230 12 5.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1146Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.50 230 7 3.0% 1 +[H69-,V70-,H146Y,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.50 230 5 2.2% 2 +[H69-,V70-,E169K,V213G,G339D,L452R,F486V,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.50 230 5 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.133 229 138 60.3% 0 +[N17K,L18F,T19R,E156G,F157-,R158-,A222V,L452R,P499R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.133 229 45 19.7% 1 +[N17K,L18F,T19R,E156G,F157-,R158-,E180A,A222V,L452R,P499R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.133 229 12 5.2% 1 +[N17K,L18F,T19R,E156G,F157-,R158-,A222V,L452R,P499R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.133 229 4 1.7% 1 +[N17K,L18F,T19R,E156G,F157-,R158-,A222V,L452R,P499R,P681R,D950N,L1063F,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.133 229 4 1.7% 4 +[N17K,L18F,T19R,T29I,H49Y,E156G,F157-,R158-,A222V,L452R,P479S,P499R,D574Y,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.21 229 183 79.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.21 229 4 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.21 229 3 1.3% 2 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.21 229 3 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.21 229 3 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,N1178S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.39 228 208 91.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.39 228 8 3.5% 1 +[C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.39 228 3 1.3% 1 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.39 228 2 0.9% 2 +[H146-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.39 228 1 0.4% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HT.1 228 121 53.1% 0 +[N148T] (consensus) HT.1 228 16 7.0% 1 +[L84I,N148T] HT.1 228 6 2.6% 1 +[N148T,T478R]-[T478K] HT.1 228 6 2.6% 1 +[N148T]-[K417N] HT.1 228 5 2.2% 1 +[N148T,N185D] CH.1.1.13 227 159 70.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.13 227 50 22.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T734I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.13 227 3 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T302S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.13 227 3 1.3% 1 +[K147E,W152R,F157L,T208M,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.13 227 2 0.9% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBB.1.5.8 226 127 56.2% 0 (consensus) XBB.1.5.8 226 17 7.5% 1 +[P1162S] XBB.1.5.8 226 14 6.2% 1 +[P463S] XBB.1.5.8 226 10 4.4% 1 +[W152R] XBB.1.5.8 226 8 3.5% 1 +[S98F] XBB.1.16.20 226 85 37.6% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.20 226 67 29.6% 1 +[E180V,T478R,T573I]-[T478K] XBB.1.16.20 226 10 4.4% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.20 226 8 3.5% 1 +[E180V,T478R]-[K417N,T478K] XBB.1.16.20 226 4 1.8% 1 +[E180V,T478R]-[Y144-,T478K] CM.10 226 104 46.0% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,V445A,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] (consensus) CM.10 226 21 9.3% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,V445A,N450D,L452M,E484R,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] CM.10 226 9 4.0% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,V445A,N450D,L452M,E484R,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] CM.10 226 8 3.5% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,V445A,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,T478K,E484A,F486P,F490S] CM.10 226 4 1.8% 1 +[N164K,V213G,H245N,G257D,G339D,K444R,V445A,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] B.1.177.23 225 142 63.1% 0 +[V90F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.23 225 60 26.7% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.23 225 3 1.3% 1 +[V90F,A222V,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.23 225 2 0.9% 3 +[A222V,D574Y,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.23 225 2 0.9% 2 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.186 225 196 87.1% 0 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.186 225 4 1.8% 1 +[A67S,D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.186 225 3 1.3% 1 +[D138H,A899V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.186 225 3 1.3% 1 +[A67V,D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.186 225 2 0.9% 1 +[D138H,A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.28 223 174 78.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.28 223 34 15.2% 1 +[A846S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.28 223 5 2.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.28 223 2 0.9% 1 +[P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.28 223 1 0.4% 1 +[G1267R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.30 223 168 75.3% 0 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.30 223 26 11.7% 1 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.30 223 6 2.7% 1 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V,Q613E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.30 223 3 1.3% 2 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N679K,P681H] BA.5.2.30 223 3 1.3% 1 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.36.9 223 170 76.2% 0 +[I210-,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.9 223 27 12.1% 1 +[I210-,T859N,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.9 223 10 4.5% 2 +[I210-,A653V,T859N,P1263R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.9 223 3 1.3% 1 +[I210-,Q787K,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.9 223 2 0.9% 1 +[V70F,I210-,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.337 222 158 71.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.337 222 27 12.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.337 222 8 3.6% 1 +[H655R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.337 222 4 1.8% 1 +[K854N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.337 222 4 1.8% 2 +[K854N,M900I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GP.3 222 170 76.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) GP.3 222 10 4.5% 1 +[K147E,W152R,F157L,Y200C,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GP.3 222 6 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,G932S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GP.3 222 4 1.8% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GP.3 222 4 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.567 222 137 61.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.567 222 24 10.8% 1 +[P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.567 222 16 7.2% 1 +[E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.567 222 8 3.6% 1 +[K1245R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.567 222 5 2.3% 1 +[N282K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.7 222 186 83.8% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.7 222 6 2.7% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.7 222 5 2.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,G446S,N460K,F486P,F490S] BA.1.7 222 4 1.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,G1171S]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.7 222 2 0.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L938F,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] DZ.2 222 159 71.6% 0 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DZ.2 222 14 6.3% 1 +[T19L,H69-,V70-,G75V,V213G,G339D,L452R,F486V,T883I]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DZ.2 222 6 2.7% 1 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V,T883I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DZ.2 222 5 2.3% 1 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DZ.2 222 4 1.8% 1 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V,T883I,C1236S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.16.4 222 119 53.6% 0 +[E180V,T478R,T678I]-[T478K] (consensus) XBB.1.16.4 222 16 7.2% 1 +[E180V,T478R,T678I,S1252F]-[T478K] XBB.1.16.4 222 16 7.2% 1 +[E180V,F456L,T478R,T678I]-[T478K] XBB.1.16.4 222 11 5.0% 1 +[E180V,T478R,Q677H,T678I]-[T478K] XBB.1.16.4 222 7 3.2% 3 +[I68T,E180V,S256L,T478R,T678I,A694V]-[T478K] B.1.1.258 221 157 71.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.258 221 20 9.0% 1 +[G72E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.258 221 14 6.3% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.258 221 7 3.2% 2 +[G72E,D985N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.258 221 5 2.3% 1 +[L1224F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.5.5 221 165 74.7% 0 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.5.5 221 27 12.2% 1 +[H69-,V70-,K147N,V213G,G339D,T430I,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.5 221 4 1.8% 2 +[H69-,V70-,K147N,V213G,F306L,G339D,L452R,E484V,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,E484A,F486P,F490S] BF.5.5 221 3 1.4% 1 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V,T547K,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.5 221 3 1.4% 1 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.36.7 221 151 68.3% 0 +[I210-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.7 221 38 17.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.7 221 3 1.4% 2 +[T676I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.7 221 3 1.4% 1 +[I210-,T676I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.7 221 2 0.9% 2 +[I210-,Q675H,T678S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.10.1 221 126 57.0% 0 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.10.1 221 50 22.6% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.10.1 221 7 3.2% 2 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V,E619D,Q1201R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.10.1 221 4 1.8% 2 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V,D1084E]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.10.1 221 3 1.4% 3 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V,D1084E]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,N460K,F486P,F490S] EZ.1 221 165 74.7% 0 +[H69-,V70-,V213G,+246N,Y248-,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EZ.1 221 6 2.7% 1 +[H69-,V70-,V213G,+246N,Y248-,G339D,K444T,L452R,F486V,Q613H,D627Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EZ.1 221 5 2.3% 1 +[H69-,V70-,V213G,+246N,Y248-,E324G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EZ.1 221 3 1.4% 1 +[H69-,V70-,V213G,+246N,Y248-,G339D,K444T,L452R,F486V,Q613H,Y1110F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EZ.1 221 3 1.4% 1 +[H69-,V70-,V213G,+246N,Y248-,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] B.1.558 220 120 54.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.558 220 25 11.4% 2 +[E309Q,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.558 220 11 5.0% 1 +[E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.558 220 7 3.2% 1 +[A1070V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.558 220 7 3.2% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.469 220 134 60.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.469 220 13 5.9% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.469 220 8 3.6% 2 +[D80Y,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.469 220 8 3.6% 1 +[Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.469 220 6 2.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.4 220 138 62.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.4 220 43 19.5% 1 +[F565L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.4 220 12 5.5% 2 +[T29I,F565L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.4 220 2 0.9% 2 +[V90F,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.4 220 2 0.9% 1 +[T1238N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.146 219 111 50.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.146 219 22 10.0% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.146 219 18 8.2% 1 +[G1085R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.146 219 17 7.8% 1 +[T299I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.146 219 7 3.2% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.1 219 167 76.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AD.1 219 38 17.4% 1 +[P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.1 219 6 2.7% 1 +[A1070S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.1 219 4 1.8% 1 +[M740I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.1 219 2 0.9% 2 +[G142S,T299I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JD.1.2 219 58 26.5% 0 +[L455F,F456L,E554Q,P1162S] JD.1.2 219 34 15.5% 1 +[L455F,F456L,P1162S] (consensus) JD.1.2 219 13 5.9% 3 +[L455F,F456L,P1162S]-[R346T,K417N] JD.1.2 219 10 4.6% 2 +[L455F,F456L,A1078T,P1162S] JD.1.2 219 7 3.2% 2 +[L455F,F456L,P1162S]-[R346T] FL.4.11 219 142 64.8% 0 +[D1259Y] (consensus) FL.4.11 219 27 12.3% 1 +[E156V,D1259Y] FL.4.11 219 8 3.7% 1 +[H146K,D1259Y]-[H146Q] FL.4.11 219 5 2.3% 1 +[A783S,D1259Y] FL.4.11 219 3 1.4% 1 +[G482R,D1259Y] JN.1.8.3 218 110 50.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.8.3 218 29 13.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.8.3 218 8 3.7% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.8.3 218 8 3.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,R190K,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.8.3 218 7 3.2% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157L,R158G,R190K,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.634 218 134 61.5% 0 +[L18R,H69-,V70-,T95I,R158S,E484K,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,D796Y,Q954H,N969K] (consensus) B.1.634 218 31 14.2% 1 +[L18R,H69-,V70-,T95I,R158S,E484K,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,D796Y,Q954H,N969K] B.1.634 218 11 5.0% 2 +[L18R,H69-,V70-,T95I,R158S,E484K,A688V,E1258D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,D796Y,Q954H,N969K] B.1.634 218 2 0.9% 1 +[L18R,H69-,V70-,T95I,R158S,E484K,A688V,A1070S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,D796Y,Q954H,N969K] B.1.634 218 2 0.9% 3 +[L18R,H69-,V70-,T95I,R158S,E484K,A688V,E1258-,+1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,D796Y,Q954H,N969K] B.1.258.7 218 178 81.7% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.7 218 18 8.3% 2 +[H69-,V70-,N439K,E583D,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.7 218 6 2.8% 1 +[H69-,V70-,K310R,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.7 218 3 1.4% 1 +[H69-,V70-,N439K,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.7 218 2 0.9% 2 +[H69-,V70-,N439K,L752F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.1.74 218 201 92.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.74 218 10 4.6% 1 +[N481D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.74 218 6 2.8% 1 +[P25S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.74 218 1 0.5% 2 +[E180G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.64 218 155 71.1% 0 (consensus) XBB.1.5.64 218 15 6.9% 1 +[D1259E] XBB.1.5.64 218 5 2.3% 1 +[V1264L] XBB.1.5.64 218 5 2.3% 1 +[T478R]-[T478K] XBB.1.5.64 218 4 1.8% 1 +[H146K]-[H146Q] CH.1.1.14 218 112 51.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.14 218 34 15.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q836R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.14 218 18 8.3% 2 +[K147E,W152R,F157L,I210V,G257S,A348S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F486P,F490S] CH.1.1.14 218 17 7.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.14 218 6 2.8% 1 +[K147E,W152R,F157L,I210V,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F486P,F490S] AY.123.1 217 75 34.6% 0 +[T19R,T95I,E156G,F157-,R158-,D178N,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.123.1 217 73 33.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.123.1 217 27 12.4% 2 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.123.1 217 9 4.1% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,C1248R,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.123.1 217 8 3.7% 1 +[T19R,T95I,E156G,F157-,R158-,D178N,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XJ 217 196 90.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XJ 217 4 1.8% 1 +[V213G,G339D,Q493R,T676I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XJ 217 3 1.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XJ 217 2 0.9% 2 +[V213G,G339D,Q493R,L922S,Y1215H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XJ 217 1 0.5% 2 +[V213G,G339D,V445I,Q493R,G832V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BW.1.1.2 216 183 84.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BW.1.1.2 216 4 1.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BW.1.1.2 216 3 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,V445A,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1.1.2 216 2 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,G891D]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1.1.2 216 2 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,T678I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.459 215 47 21.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.459 215 35 16.3% 1 +[S689R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.459 215 26 12.1% 2 +[L18F,S689R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.459 215 15 7.0% 2 +[S689R,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.459 215 13 6.0% 1 +[V213A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.401 214 128 59.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.401 214 46 21.5% 1 +[S151I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.401 214 19 8.9% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.401 214 5 2.3% 2 +[D178N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.401 214 2 0.9% 1 +[L1265P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.340 214 156 72.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.340 214 17 7.9% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.340 214 15 7.0% 1 +[I233V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.340 214 6 2.8% 3 +[D198G,T676A,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.340 214 5 2.3% 1 +[T573I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XN 214 204 95.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XN 214 2 0.9% 1 +[V213G,G339D,Q493R,C1248Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XN 214 2 0.9% 1 +[V193L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XN 214 1 0.5% 1 +[V213G,G339D,T478R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,T478K,F486P,F490S] XN 214 1 0.5% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] B.1.177.30 213 180 84.5% 0 +[D80Y,N164T,A222V,A262S,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.30 213 25 11.7% 1 +[L5F,D80Y,N164T,A222V,A262S,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.30 213 2 0.9% 1 +[D80Y,N164T,A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.30 213 1 0.5% 1 +[D80Y,P139L,N164T,A222V,A262S,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.30 213 1 0.5% 1 +[D80Y,N164T,A222V,A262S,E583D,A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.3 213 68 31.9% 0 +[L452R,Y1155F,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) L.3 213 40 18.8% 1 +[G75R,L452R,Y1155F,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.3 213 34 16.0% 2 +[V308L,L452R,Q675H,Y1155F,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.3 213 8 3.8% 2 +[G75R,L452R,E484Q,Y1155F,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.3 213 5 2.3% 1 +[V213L,L452R,Y1155F,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GE.1.3 213 113 53.1% 0 +[N185I,F186-,D253G,T478R,P521S,T732I]-[G252V,T478K] (consensus) GE.1.3 213 11 5.2% 1 +[N185I,F186-,D253G,T478R,P521S,A701V,T732I]-[G252V,T478K] GE.1.3 213 10 4.7% 1 +[T19L,N185I,F186-,D253G,T478R,P521S,T732I]-[T19I,G252V,T478K] GE.1.3 213 8 3.8% 1 +[H146K,N185I,F186-,D253G,T478R,P521S,T732I]-[H146Q,G252V,T478K] GE.1.3 213 4 1.9% 1 +[N185I,F186-,D253G,T478R,P521S,Q677H,T732I]-[G252V,T478K] BA.1.21.1 213 122 57.3% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.21.1 213 21 9.9% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.21.1 213 12 5.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.21.1 213 12 5.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.21.1 213 4 1.9% 8 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,D215E,G339D,S371L,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S,N679K,N764K] BF.7.18 213 182 85.4% 0 +[H69-,V70-,K97N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.18 213 3 1.4% 2 +[H69F,V70-,S71-,K97N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.18 213 3 1.4% 1 +[H69-,V70-,K97N,V213G,G339D,L452R,F486V,G1219C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.18 213 3 1.4% 1 +[H69-,V70-,K97N,I105V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.18 213 3 1.4% 3 +[K97N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] XBB.1.5.79 213 97 45.5% 0 (consensus) XBB.1.5.79 213 19 8.9% 2 +[G261V,K304Q] XBB.1.5.79 213 15 7.0% 1 -[K417N] XBB.1.5.79 213 6 2.8% 1 -[G142D] XBB.1.5.79 213 6 2.8% 1 +[S255F] B.1.1.305 212 111 52.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.305 212 15 7.1% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.305 212 14 6.6% 1 +[D215N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.305 212 8 3.8% 2 +[L18F,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.305 212 5 2.4% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.280 212 149 70.3% 0 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.280 212 32 15.1% 1 +[M153T,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.280 212 7 3.3% 1 +[M153T,Y453F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.280 212 5 2.4% 1 +[M153T,P251L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.280 212 5 2.4% 1 +[M153T,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.159 212 105 49.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.159 212 26 12.3% 1 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.159 212 13 6.1% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.159 212 12 5.7% 2 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.159 212 9 4.2% 2 +[A871V,T1117R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.9 212 116 54.7% 0 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.9 212 43 20.3% 1 +[A344S,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.9 212 5 2.4% 1 +[L176F,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.9 212 3 1.4% 1 +[P25T,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.9 212 3 1.4% 1 +[L18F,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBD 212 101 47.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) XBD 212 18 8.5% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,F486S,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBD 212 17 8.0% 2 +[K147E,W152R,F157L,N188S,I210V,V213G,G257S,F486S,A1020S,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBD 212 15 7.1% 2 +[H69-,V70-,K147E,W152R,F157L,I210V,V213G,G257S,F486S,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBD 212 7 3.3% 2 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,F486S,A1020S,D1139N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BB.1 212 90 42.5% 0 +[T95I,Y144N,Y145-,R346K,Y449N,E484K,E583D,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) BB.1 212 67 31.6% 3 +[T95I,+143T,Y144S,Y145N,R346K,Y449N,E484K,E583D,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BB.1 212 8 3.8% 4 +[T95I,+143T,Y144S,Y145N,D215H,R346K,Y449N,E484K,E583D,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BB.1 212 4 1.9% 4 +[T95I,+143T,Y144S,Y145N,R346K,Y449N,E484K,T572I,E583D,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BB.1 212 3 1.4% 5 +[T95I,+143T,Y144S,Y145N,K150N,R346K,Y449N,E484K,E583D,D950N,D1168E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BQ.1.1.76 212 179 84.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.76 212 7 3.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.76 212 5 2.4% 1 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.76 212 4 1.9% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.76 212 4 1.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.22 211 104 49.3% 0 +[T19R,T95I,E156G,F157-,R158-,Q218H,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.22 211 36 17.1% 1 +[T19R,T95I,E156G,F157-,R158-,Q218H,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.22 211 15 7.1% 3 +[T19R,L54F,T95I,E156G,F157-,R158-,M177I,Q218H,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.22 211 14 6.6% 1 +[T19R,T95I,E156G,F157-,R158-,M177I,Q218H,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.22 211 6 2.8% 2 +[T19R,T95I,E156G,F157-,R158-,M177I,Q218H,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.6 211 117 55.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BN.6 211 22 10.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,G446T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,F486P,F490S] BN.6 211 10 4.7% 1 +[N99D,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BN.6 211 7 3.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S477K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,F486P,F490S] BN.6 211 6 2.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.78 211 70 33.2% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.78 211 39 18.5% 2 +[V213G,S254F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.78 211 13 6.2% 32 +[R34L,A123S,V213G,R214L,G339D,A344S,+370F,A372P,S373F,T376-,A411S,V433F,G476C,Q493L,Q498L,R577L,R634L,R646L,A672S,R682L,R683L,R685L,R765L,G857C,R983L,R1091L,R1185L,D1199Y,D1260Y]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,N440K,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.78 211 12 5.7% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.78 211 11 5.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CB.1 211 173 82.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CB.1 211 7 3.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CB.1 211 3 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] CB.1 211 2 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486V,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CB.1 211 2 0.9% 6 +[K147E,W152R,F157L,D178N,I210V,V213G,G257S,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CK.1.3 211 145 68.7% 0 +[H69-,V70-,F157L,G181V,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1.3 211 23 10.9% 1 +[H69-,V70-,F157L,G181V,V213G,G339D,K444N,L452R,F486V,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.3 211 11 5.2% 1 +[H69-,V70-,F157L,G181V,V213G,S254F,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.3 211 4 1.9% 1 +[H69-,V70-,F157L,G181V,V213G,G219D,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.3 211 3 1.4% 1 +[H69-,V70-,F157L,G181V,V213G,G339D,K444N,L452R,F486V,A831V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBB.1.5.3 211 167 79.1% 0 +[A411S] (consensus) XBB.1.5.3 211 4 1.9% 1 +[V3I,A411S] XBB.1.5.3 211 4 1.9% 1 +[A411S,T478R]-[T478K] XBB.1.5.3 211 3 1.4% 1 +[A411S,V642G] XBB.1.5.3 211 3 1.4% 1 +[K304Q,A411S] B.1.1.227 211 202 95.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.227 211 4 1.9% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.227 211 1 0.5% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.227 211 1 0.5% 1 +[A522S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.227 211 1 0.5% 1 +[E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.75.4 210 82 39.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75.4 210 27 12.9% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.4 210 18 8.6% 3 +[T29S,K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.4 210 12 5.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,T478I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,F486P,F490S] BA.2.75.4 210 11 5.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.79 209 155 74.2% 0 +[V213G,Y248S,G339D,N450D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.79 209 10 4.8% 1 +[K182E,V213G,Y248S,G339D,N450D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.79 209 7 3.3% 1 +[V213G,Y248S,G339D,N450D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.79 209 5 2.4% 1 +[V213G,Y248S,G339D,N450D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.79 209 4 1.9% 1 +[V213G,Y248S,G339D,N450D,Q493R,P1143S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.21 208 56 26.9% 0 +[F456L] FL.21 208 46 22.1% 2 +[D1084N] FL.21 208 41 19.7% 1 (consensus) FL.21 208 7 3.4% 3 +[E554A,D1084N] FL.21 208 7 3.4% 2 +[G1124V] EW.2 207 175 84.5% 0 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,A701V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EW.2 207 5 2.4% 4 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,A701V,N856S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EW.2 207 3 1.4% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,A701V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EW.2 207 3 1.4% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,A701V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] EW.2 207 2 1.0% 1 +[H69-,V70-,H146Y,V213G,P251L,G339D,K444T,L452R,F486V,A701V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BF.7.3 207 155 74.9% 0 +[H69-,V70-,K182E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.3 207 6 2.9% 1 +[H69-,V70-,K182E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.7.3 207 5 2.4% 1 +[H69-,V70-,K182E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.3 207 4 1.9% 2 +[H69-,V70-,K182E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,N679K,P681H] BF.7.3 207 3 1.4% 1 +[H69-,V70-,K182E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,P681H] B.1.179 207 179 86.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.179 207 16 7.7% 2 +[H49Y,S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.179 207 5 2.4% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.179 207 3 1.4% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.179 207 1 0.5% 1 +[K278I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.8 207 158 76.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,A846V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.8 207 9 4.3% 1 +[K147E,W152R,F157L,G184D,I210V,V213G,G257S,K444T,L452R,F486S,A846V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.8 207 6 2.9% 1 +[T95A,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,A846V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.8 207 6 2.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,A846V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,N764K] CH.1.1.8 207 4 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,V642F,A846V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CL.1.2 207 100 48.3% 0 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CL.1.2 207 22 10.6% 5 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V,T883I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CL.1.2 207 10 4.8% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N764K] CL.1.2 207 9 4.3% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V,T883I]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CL.1.2 207 8 3.9% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,H655Y] XBC.1.6.3 207 171 82.6% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.6.3 207 16 7.7% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,A942T]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.3 207 2 1.0% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,L1203F]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.3 207 2 1.0% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,C1248R]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.3 207 1 0.5% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N603T,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] B.11 206 157 76.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.11 206 27 13.1% 1 +[Y453F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.11 206 7 3.4% 2 +[G261D,Y453F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.11 206 2 1.0% 2 +[V367F,Y453F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.11 206 2 1.0% 1 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.92 206 109 52.9% 0 (consensus) XBB.1.5.92 206 34 16.5% 1 -[R408S] XBB.1.5.92 206 3 1.5% 2 +[N450Y,V1228L] XBB.1.5.92 206 2 1.0% 1 +[T553I] XBB.1.5.92 206 2 1.0% 1 +[P1162L] ES.1 206 193 93.7% 0 +[Q52R,H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) ES.1 206 3 1.5% 1 +[Q52R,H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V,L582F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ES.1 206 2 1.0% 1 +[Q52R,H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ES.1 206 2 1.0% 1 +[Q52R,H69-,V70-,K147I,V213G,R237K,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ES.1 206 1 0.5% 1 +[Q52R,H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V,V860L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.625 205 101 49.3% 0 +[H69-,V70-,T95I,F157L,E484K,D950N,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.625 205 11 5.4% 1 +[H69-,V70-,T95I,N149T,F157L,E484K,D950N,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.625 205 7 3.4% 1 +[H69-,V70-,T95I,F157L,E484K,D950N,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.625 205 5 2.4% 1 +[H69-,V70-,T95I,F157L,E484K,D950N,V1228L,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.625 205 4 2.0% 1 +[H69-,V70-,T95I,F157L,E484K,D950N,D1084Y,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.541 205 92 44.9% 0 +[A67S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.541 205 92 44.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.541 205 6 2.9% 1 +[A67S,E154D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.541 205 3 1.5% 1 +[L5F,A67S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.541 205 2 1.0% 3 +[P384L,A570V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.1 205 149 72.7% 0 +[H69-,V70-,V213G,G261V,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.1 205 13 6.3% 5 +[H69-,V70-,V213G,G261V,G339D,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.1 205 7 3.4% 1 +[H69-,V70-,V213G,G261V,G339D,L452R,F486V,I1232F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.1 205 5 2.4% 1 +[H69-,V70-,V213G,G261V,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.1 205 3 1.5% 1 +[L5F,H69-,V70-,V213G,G261V,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EB.1 205 171 83.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) EB.1 205 5 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EB.1 205 4 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P812S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EB.1 205 3 1.5% 1 +[H69-,V70-,V213G,G339D,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EB.1 205 3 1.5% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.37 204 105 51.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.37 204 27 13.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.37 204 10 4.9% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.37 204 6 2.9% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.37 204 5 2.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] B.1.377 204 168 82.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.377 204 5 2.5% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.377 204 5 2.5% 1 +[T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.377 204 3 1.5% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.377 204 3 1.5% 2 +[H49Y,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DC.1 204 149 73.0% 0 +[H69-,V70-,V213G,G339D,L452R,N460S,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DC.1 204 17 8.3% 1 +[H69-,V70-,K150N,V213G,G339D,L452R,N460S,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DC.1 204 16 7.8% 2 +[H69-,V70-,W152R,V213G,G339D,L452R,N460S,F486V,N658S,D1153G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DC.1 204 6 2.9% 1 +[H69-,V70-,V213G,G339D,L452R,N460S,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] DC.1 204 2 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,N460S,F486V,I651V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BN.5 204 116 56.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BN.5 204 28 13.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BN.5 204 7 3.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,F486P,F490S] BN.5 204 6 2.9% 1 +[L54F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BN.5 204 5 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,M740L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] B.1.1.191 204 198 97.1% 0 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.191 204 1 0.5% 1 +[A344S,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.191 204 1 0.5% 1 +[D614V,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.191 204 1 0.5% 1 +[R683L,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.191 204 1 0.5% 1 +[K444R,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FP.4 204 126 61.8% 0 (consensus) FP.4 204 11 5.4% 1 +[F456L] FP.4 204 5 2.5% 1 -[K417N] FP.4 204 5 2.5% 2 +[F55Y,T572I] FP.4 204 4 2.0% 1 +[H146K]-[H146Q] FY.1 204 65 31.9% 0 +[Y200C] (consensus) FY.1 204 40 19.6% 4 +[N185S,Y200C,T478R,I569T,D1084G]-[T478K] FY.1 204 18 8.8% 3 +[Y200C,T478R,I569T,D1084G]-[T478K] FY.1 204 10 4.9% 2 +[Y200C,T478R,D1084G]-[T478K] FY.1 204 6 2.9% 1 +[Y200C,T791I] B.45 204 181 88.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.45 204 11 5.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.45 204 5 2.5% 1 +[Y28H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.45 204 1 0.5% 1 +[S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.45 204 1 0.5% 1 +[T1009I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.55 203 154 75.9% 0 +[I68T,V213G,G339D,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.55 203 31 15.3% 1 +[I68T,V213G,H245Y,G339D,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.55 203 3 1.5% 1 +[I68T,V213G,G339D,Q493R,T941S,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.55 203 3 1.5% 1 +[I68T,V213G,G339A,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.55 203 2 1.0% 2 +[I68T,V213G,G339A,Q493R,T941S,M1050I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] KW.1 203 161 79.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KW.1 203 7 3.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KW.1 203 5 2.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KW.1 203 2 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,N824D,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KW.1 203 2 1.0% 3 +[+16MPLF,R21T,S50L,H69-,V70-,T95S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] AY.127.1 203 154 75.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T859N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.127.1 203 10 4.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,L828V,T859N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127.1 203 9 4.4% 3 +[T19R,T95I,V143F,M153I,E156G,F157-,R158-,L452R,P681R,T859N,D936N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127.1 203 7 3.4% 2 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,A522V,P681R,T859N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127.1 203 7 3.4% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,T859N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.67 203 89 43.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.67 203 61 30.0% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.67 203 20 9.9% 1 +[F157S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.67 203 15 7.4% 2 +[F157S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.67 203 4 2.0% 4 +[F157S,V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] FL.29 202 125 61.9% 0 +[F490P]-[F490S] (consensus) FL.29 202 11 5.4% 2 +[S98F,F490P,P1162S]-[F490S] FL.29 202 5 2.5% 1 +[S112L,F490P]-[F490S] FL.29 202 4 2.0% 1 +[F490P,C1243F]-[F490S] FL.29 202 3 1.5% 1 +[N74S,F490P]-[F490S] B.1.160.24 202 121 59.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.24 202 51 25.2% 2 +[G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.24 202 24 11.9% 1 +[A879T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.24 202 2 1.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.24 202 1 0.5% 2 +[A879T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.135 201 174 86.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.135 201 5 2.5% 1 +[A575S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.135 201 4 2.0% 1 +[W152R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.135 201 3 1.5% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.135 201 2 1.0% 1 +[T323I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.6.1 201 164 81.6% 0 -[G252V] (consensus) XBB.6.1 201 4 2.0% 1 -[G252V,K417N] XBB.6.1 201 2 1.0% 1 +[Q1113L]-[G252V] XBB.6.1 201 2 1.0% 1 +[Q493L]-[G252V] XBB.6.1 201 2 1.0% 1 +[A260S]-[G252V] B.1.575.2 201 195 97.0% 0 +[R102G,E484K,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.575.2 201 1 0.5% 1 +[R102G,E484K,S494P,T716I,T912I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575.2 201 1 0.5% 1 +[T19R,R102G,E484K,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575.2 201 1 0.5% 1 +[R102G,E484K,S494P,Q677H,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575.2 201 1 0.5% 1 +[R102G,E484K,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XBB.2.3.7 201 86 42.8% 0 +[D253G,P521S,P1263R]-[G252V] (consensus) XBB.2.3.7 201 52 25.9% 1 +[D253G,P521S]-[G252V] XBB.2.3.7 201 14 7.0% 1 +[D253G,Q314E,P521S,P1263R]-[G252V] XBB.2.3.7 201 4 2.0% 2 +[L5F,D253G,P521S]-[G252V] XBB.2.3.7 201 3 1.5% 2 +[D253G,T478Q,P521S]-[G252V,T478K] JN.1.1.1 200 121 60.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.1.1 200 12 6.0% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.1 200 7 3.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.1 200 5 2.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.1 200 3 1.5% 1 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] DG.1 199 152 76.4% 0 +[H69-,V70-,V213G,G252S,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) DG.1 199 13 6.5% 1 +[H69-,V70-,V213G,G252S,S255F,G339D,K444N,L452R,F486V,F490L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DG.1 199 5 2.5% 1 +[H69-,V70-,V213G,G252S,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] DG.1 199 3 1.5% 1 +[H69-,V70-,V213G,G252S,S255F,A262D,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DG.1 199 3 1.5% 1 +[H69-,V70-,V213G,G252S,S255F,G339D,K444N,L452R,F486V,S943N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] C.37.1 199 87 43.7% 0 +[R21I,G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,T572I,Q675H,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.37.1 199 36 18.1% 4 +[G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,V826L,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.37.1 199 28 14.1% 3 +[G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.37.1 199 13 6.5% 2 +[G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,Q675H,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.37.1 199 8 4.0% 8 +[R21I,G75V,T76I,L452Q,T572I,Q675H,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FH.1 199 114 57.3% 0 +[T883I] (consensus) FH.1 199 11 5.5% 1 +[S256L,T883I] FH.1 199 8 4.0% 1 +[A688V,T883I] FH.1 199 7 3.5% 1 +[N481Y,T883I] FH.1 199 5 2.5% 2 +[T883I]-[R408S,S477N] XBC.1.6.2 199 161 80.9% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.6.2 199 7 3.5% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.2 199 5 2.5% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,H1101Y]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.2 199 4 2.0% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,T778I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.2 199 4 2.0% 1 +[S12F,P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] D.5 198 179 90.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) D.5 198 6 3.0% 1 +[D88N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.5 198 2 1.0% 1 +[T323I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.5 198 2 1.0% 1 +[S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.5 198 1 0.5% 1 +[D839N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.97 198 130 65.7% 0 +[T941S] (consensus) XBB.1.5.97 198 19 9.6% 2 +[T941S,A1070S,G1124V] XBB.1.5.97 198 8 4.0% 3 +[T941S,A1070S,G1124V,P1162L] XBB.1.5.97 198 4 2.0% 1 +[A831V,T941S] XBB.1.5.97 198 3 1.5% 1 +[G485A,T941S] DV.7 197 156 79.2% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.7 197 9 4.6% 2 +[K147E,W152R,F157L,N185D,I210V,V213G,P217S,G257S,K444T,L452R,F486S,S494P,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7 197 4 2.0% 1 +[R78K,K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7 197 2 1.0% 2 +[L5F,K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,R765L,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7 197 2 1.0% 1 +[D111N,K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JG.1 196 132 67.3% 0 +[Q52H,F456L,T732I] (consensus) JG.1 196 5 2.6% 1 +[Q52H,H146K,F456L,T732I]-[H146Q] JG.1 196 5 2.6% 1 +[Q52H,F456L,S494P,T732I] JG.1 196 5 2.6% 1 +[Q14R,Q52H,F456L,T732I] JG.1 196 4 2.0% 1 +[Q52H,F456L,T732I,A1087S] AY.75.2 196 75 38.3% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.75.2 196 51 26.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75.2 196 42 21.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75.2 196 3 1.5% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75.2 196 2 1.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,I1114S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.5.2 196 187 95.4% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.5.2 196 2 1.0% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,A1020S,R1107K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.2 196 1 0.5% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,P631S,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.2 196 1 0.5% 1 +[H69-,V70-,V213G,S247N,G339D,V445A,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.2 196 1 0.5% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,G832D,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EQ.1 196 168 85.7% 0 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) EQ.1 196 4 2.0% 1 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] EQ.1 196 4 2.0% 1 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] EQ.1 196 3 1.5% 1 +[Q14H,H69-,V70-,V213G,Q218H,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EQ.1 196 2 1.0% 1 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,V911I,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.40 195 126 64.6% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.40 195 55 28.2% 1 +[T22I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.40 195 2 1.0% 1 +[L216F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.40 195 2 1.0% 1 +[A222V,Q414L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.40 195 2 1.0% 1 +[A222V,A701S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.20 195 156 80.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.20 195 6 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.20 195 4 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.20 195 4 2.1% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.20 195 3 1.5% 1 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.27 195 151 77.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.27 195 15 7.7% 1 +[H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.27 195 5 2.6% 1 +[A626V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.27 195 4 2.1% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.27 195 2 1.0% 1 +[T678I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GW.1 195 157 80.5% 0 +[E554K] (consensus) GW.1 195 5 2.6% 1 +[E554K,I1115T] GW.1 195 4 2.1% 2 +[D111N,E554K,G1223C] GW.1 195 4 2.1% 1 +[D228H,E554K] GW.1 195 3 1.5% 1 +[T323I,E554K] BQ.1.1.26 194 123 63.4% 0 +[H69-,V70-,N185T,V213G,G339D,K444T,L452R,E471Q,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.26 194 24 12.4% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,E471Q,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.26 194 12 6.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,E471Q,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.26 194 3 1.5% 3 +[H69-,V70-,V213G,G339D,K444T,L452R,E471Q,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.26 194 3 1.5% 1 +[H69-,V70-,N185T,V213G,G339D,K444T,L452R,E471Q,F486V]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.362.2 194 183 94.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.362.2 194 2 1.0% 1 +[K1073R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362.2 194 1 0.5% 2 +[V16F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362.2 194 1 0.5% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362.2 194 1 0.5% 1 +[P807L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.3 194 153 78.9% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,R408S,V445P,N460K,F486P,F490S] (consensus) BA.3 194 11 5.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,R408S,V445P,N460K,F486P,F490S,P681H] BA.3 194 8 4.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,R408S,K417N,V445P,N460K,F486P,F490S] BA.3 194 5 2.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339Y,K417T,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,K417N,V445P,N460K,F486P,F490S] BA.3 194 2 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,Q183R,N211-,L212I,G339D,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,R408S,V445P,N460K,F486P,F490S] DV.1 194 157 80.9% 0 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.1 194 5 2.6% 1 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,T1117I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.1 194 3 1.5% 1 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.1 194 3 1.5% 2 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I651T,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.1 194 3 1.5% 1 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,A688S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FL.20.1 193 128 66.3% 0 +[Q52H,L455W,F456L] (consensus) FL.20.1 193 12 6.2% 2 +[Q52H,L455W,F456L,T732I,K1191N] FL.20.1 193 4 2.1% 1 +[Q52H,I68T,L455W,F456L] FL.20.1 193 4 2.1% 1 +[Q52H,L455W,F456L]-[K417N] FL.20.1 193 3 1.6% 1 +[Q52H,H146K,L455W,F456L]-[H146Q] Q.8 193 145 75.1% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.8 193 4 2.1% 1 +[H69-,V70-,M153I,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.8 193 3 1.6% 1 +[H69-,V70-,T95I,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.8 193 2 1.0% 2 +[H69-,V70-,A570D,V622F,T716I,A871V,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.8 193 2 1.0% 2 +[H69-,V70-,A570D,Q613H,T716I,P812R,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] DZ.1 193 148 76.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I,D1146Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DZ.1 193 6 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I,D1146Y]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DZ.1 193 4 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I,D1146Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DZ.1 193 4 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,I844V,T883I,D1146Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DZ.1 193 3 1.6% 5 +[P9L,H69-,V70-,M153T,V213G,G339D,G446R,L452R,T883I,D1146Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.2.3.12 193 61 31.6% 0 +[D253G,S494P,P521S]-[G252V] (consensus) XBB.2.3.12 193 37 19.2% 3 +[N148T,Q218R,D253G,N450D,S494P,P521S]-[G252V] XBB.2.3.12 193 24 12.4% 4 +[N148T,Q218R,D253G,N450D,F456L,S494P,P521S]-[G252V] XBB.2.3.12 193 9 4.7% 1 +[D253G,S256L,S494P,P521S]-[G252V] XBB.2.3.12 193 4 2.1% 1 +[D253G,F456L,S494P,P521S]-[G252V] JN.1.34 192 142 74.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.34 192 7 3.6% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.34 192 5 2.6% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.34 192 4 2.1% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.34 192 2 1.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.8 192 168 87.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.8 192 10 5.2% 2 +[A520S,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.8 192 2 1.0% 1 +[S221L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.8 192 1 0.5% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.8 192 1 0.5% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.2 192 80 41.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,E702V,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.23.2 192 39 20.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,E702V,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.2 192 13 6.8% 2 +[T19R,V90I,E156G,F157-,R158-,L452R,P681R,E702V,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.2 192 12 6.2% 1 +[T19R,V90I,E156G,F157-,R158-,L452R,P681R,E702V,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.2 192 5 2.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,E702V,D950N,K1157N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.51 192 142 74.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.51 192 16 8.3% 1 +[A222V,A1070V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.51 192 3 1.6% 1 +[A222V,A845V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.51 192 3 1.6% 2 +[A222V,A419S,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.51 192 3 1.6% 1 +[A222V,T941I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.3.1 192 115 59.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] (consensus) BF.3.1 192 30 15.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] BF.3.1 192 6 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] BF.3.1 192 4 2.1% 1 +[H69-,V70-,V213G,T299I,G339D,L452R,F486V,T547I,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] BF.3.1 192 4 2.1% 2 +[H69-,V70-,V213G,T299I,G339D,L452R,F486V,T547I,A1020S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] JN.6 192 119 62.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.6 192 33 17.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.6 192 3 1.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.6 192 2 1.0% 1 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.6 192 2 1.0% 1 +[+16MPLF,R21T,S50L,V62F,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBB.1.5.6 192 108 56.2% 0 +[V952I] (consensus) XBB.1.5.6 192 13 6.8% 1 +[H146K,V952I]-[H146Q] XBB.1.5.6 192 8 4.2% 2 +[Q613H,Q675H,V952I] XBB.1.5.6 192 6 3.1% 1 +[Q675H,V952I] XBB.1.5.6 192 5 2.6% 1 DV.4 192 108 56.2% 0 +[K147E,W152R,F157L,M177K,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I714V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.4 192 41 21.4% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I714V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.4 192 16 8.3% 4 +[M177K,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I714V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.4 192 4 2.1% 1 +[K147E,W152R,F157L,M177K,N185D,I210V,V213G,G257S,K444T,L452R,F486S,A626S,I714V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.4 192 3 1.6% 2 +[K147E,W152R,F157L,M177K,N185D,I210V,V213G,G257S,K444T,L452R,F486S,A626S,N703D,I714V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FD.4.1 191 152 79.6% 0 (consensus) FD.4.1 191 7 3.7% 1 +[A701V] FD.4.1 191 5 2.6% 1 +[H146K]-[H146Q] FD.4.1 191 2 1.0% 1 +[E1207D] FD.4.1 191 2 1.0% 1 +[E619D] BR.1.2 191 102 53.4% 0 +[K147E,W152R,E156Q,F157L,I210V,V213G,G257S,K444M,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BR.1.2 191 51 26.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.1.2 191 16 8.4% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S,V1133A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.1.2 191 5 2.6% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S,T1117I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.1.2 191 3 1.6% 2 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BQ.1.27 191 113 59.2% 0 +[H69-,V70-,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.27 191 16 8.4% 1 +[H69-,V70-,V213G,G339D,K444T,V445A,L452R,F486V,A1087S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.27 191 12 6.3% 2 +[H69-,V70-,V213G,Y269H,G339D,K444T,V445A,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.27 191 12 6.3% 2 +[H69-,V70-,K147I,V213G,G339D,K444T,V445A,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.27 191 6 3.1% 2 +[H69-,V70-,V213G,G339D,K444T,V445A,L452R,F486V,A1087S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FR.1.4 191 150 78.5% 0 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) FR.1.4 191 3 1.6% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,D1084A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.4 191 2 1.0% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.4 191 2 1.0% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,D1084G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.4 191 2 1.0% 2 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,A570D,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.55 191 171 89.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.55 191 3 1.6% 1 +[R765L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.55 191 2 1.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.55 191 2 1.0% 1 +[G72W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.55 191 1 0.5% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.4 189 178 94.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2.4 189 5 2.6% 1 +[G842S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.4 189 1 0.5% 1 +[E1188Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.4 189 1 0.5% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.4 189 1 0.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.12 189 124 65.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.12 189 29 15.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,R765L,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.12 189 14 7.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.12 189 3 1.6% 1 +[H69-,V70-,Q183L,V213G,G339D,L452R,F486V,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.12 189 2 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] JN.1.17 189 130 68.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.17 189 6 3.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] JN.1.17 189 5 2.6% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.17 189 5 2.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1179V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.17 189 4 2.1% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BQ.1.9 189 136 72.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.9 189 22 11.6% 1 +[H69-,V70-,G181V,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.9 189 5 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,D1146H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.9 189 3 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.9 189 2 1.1% 2 +[H69-,V70-,Y145H,V213G,G339D,K444T,L452R,F486V,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CM.3 189 144 76.2% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.3 189 7 3.7% 1 +[M153T,N164K,F186L,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.3 189 4 2.1% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.3 189 3 1.6% 1 +[M153T,N164K,L212S,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.3 189 2 1.1% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D,N679R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S,N679K] BA.5.1.20 189 153 81.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.20 189 8 4.2% 1 +[H69-,V70-,V213G,G339D,L452R,N460I,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.20 189 4 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.20 189 4 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.20 189 3 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1219V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EG.6.1.1 189 136 72.0% 0 +[L242I,F456L,E484K]-[E484A] (consensus) EG.6.1.1 189 14 7.4% 1 +[L242I,F456L,E484K,C1250Y]-[E484A] EG.6.1.1 189 5 2.6% 1 +[L242I,S256L,F456L,E484K]-[E484A] EG.6.1.1 189 2 1.1% 1 +[Q173K,L242I,F456L,E484K]-[E484A] EG.6.1.1 189 2 1.1% 1 +[L242I,F456L,E484K,Q677H]-[E484A] CH.1.1.16 188 80 42.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.16 188 52 27.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,D867N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.16 188 9 4.8% 1 +[K147E,W152R,F157L,I210V,V213G,T240I,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.16 188 7 3.7% 2 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,D867N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.16 188 4 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,G1251R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.160.29 188 159 84.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.29 188 6 3.2% 1 +[T299I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.29 188 5 2.7% 1 +[T724A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.29 188 5 2.7% 2 +[E702V,T724A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.29 188 4 2.1% 2 +[S98F,T724A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BH.1 188 137 72.9% 0 +[H69F,V70-,S71-,V213G,G339D,K417T,L452Q,T478R,Q493R,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,N460K,T478K,F486P,F490S] (consensus) BH.1 188 19 10.1% 8 +[S71F,V213G,G339D,K417T,L452Q,T478R,Q493R,V1264L]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,N460K,T478K,F486P,F490S] BH.1 188 3 1.6% 9 +[S71F,V213G,T299I,G339D,K417T,L452Q,T478R,Q493R,V1264L]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,N460K,T478K,F486P,F490S] BH.1 188 3 1.6% 1 +[H69F,V70-,S71-,V213G,G339D,K417T,L452Q,T478R,Q493R,T768I,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,N460K,T478K,F486P,F490S] BH.1 188 2 1.1% 1 +[L5F,H69F,V70-,S71-,V213G,G339D,K417T,L452Q,T478R,Q493R,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,N460K,T478K,F486P,F490S] CA.3 188 96 51.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CA.3 188 33 17.6% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444M,L452R,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.3 188 6 3.2% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.3 188 4 2.1% 1 +[K147E,W152R,F157L,Q183K,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.3 188 4 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,K1191E,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBL 188 127 67.6% 0 (consensus) XBL 188 8 4.3% 2 +[Q14H,H146K]-[H146Q] XBL 188 7 3.7% 1 +[H146K]-[H146Q] XBL 188 3 1.6% 2 +[Q14H]-[Y144-] XBL 188 3 1.6% 1 +[K182R] JN.1.33 187 94 50.3% 0 +[R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.33 187 68 36.4% 4 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.33 187 2 1.1% 5 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.33 187 2 1.1% 1 +[R21T,G35R,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.33 187 2 1.1% 1 +[L5F,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.597 187 71 38.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.597 187 20 10.7% 2 +[I203V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.597 187 11 5.9% 1 +[N30T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.597 187 5 2.7% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.597 187 5 2.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BL.6 187 134 71.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,V445A,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BL.6 187 27 14.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,V445A,G482R,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.6 187 10 5.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,V445A,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BL.6 187 1 0.5% 2 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,V445A,K529N,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.6 187 1 0.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,A348S,V445A,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XCF 187 112 59.9% 0 +[F456L] (consensus) XCF 187 18 9.6% 1 +[R78M,F456L] XCF 187 16 8.6% 1 +[F456L,A688V] XCF 187 9 4.8% 1 +[H146K,F456L]-[H146Q] XCF 187 5 2.7% 1 +[A163V,F456L] B.1.1.272 187 187 100.0% 0 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.88.1 186 156 83.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.88.1 186 11 5.9% 1 +[V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.88.1 186 8 4.3% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.88.1 186 2 1.1% 1 +[P1079S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.88.1 186 1 0.5% 2 +[Q677H,P681A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.40 186 87 46.8% 0 +[T19R,E156G,F157-,R158-,L452R,D574Y,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.40 186 61 32.8% 1 +[T19R,E156G,F157-,R158-,L452R,D574Y,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.40 186 8 4.3% 2 +[T19R,E156G,F157-,R158-,L452R,D574Y,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.40 186 7 3.8% 1 +[T19R,E156G,F157-,R158-,L452R,D574Y,P681R,D950N,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.40 186 6 3.2% 1 +[T19R,E156G,F157-,R158-,L452R,D574Y,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HK.7 186 139 74.7% 0 +[Q52H,N148T,F456L] (consensus) HK.7 186 7 3.8% 1 +[Q52H,H146K,N148T,F456L]-[H146Q] HK.7 186 4 2.2% 1 +[Q52H,N148T,F456L,G1267R] HK.7 186 3 1.6% 1 +[Q52H,N148T,E281Q,F456L] HK.7 186 3 1.6% 1 +[Q52H,N148T,L455F,F456L] BF.7.2 185 173 93.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486I,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.2 185 9 4.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486I,A570V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.2 185 1 0.5% 1 +[P9L,H69-,V70-,V213G,G339D,L452R,F486I,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.2 185 1 0.5% 2 +[P9L,H69-,V70-,V213G,G339D,L452R,F486I,H1101Y]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.2 185 1 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486I,T638I,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.26 184 123 66.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.26 184 29 15.8% 1 +[P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.26 184 21 11.4% 1 +[D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.26 184 4 2.2% 2 +[I105L,P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.26 184 3 1.6% 1 +[G476S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BG.1 184 106 57.6% 0 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] (consensus) BG.1 184 48 26.1% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.1 184 8 4.3% 1 +[V213G,G339D,L452Q,Q493R,S704L,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BG.1 184 2 1.1% 1 +[L5F,V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BG.1 184 2 1.1% 1 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] FL.4.2 184 117 63.6% 0 +[V289I] (consensus) FL.4.2 184 13 7.1% 1 +[V289I,F490A]-[F490S] FL.4.2 184 7 3.8% 1 +[H146K,V289I]-[H146Q] FL.4.2 184 4 2.2% 2 +[V289I]-[L368I,S371F] FL.4.2 184 3 1.6% 1 +[V289I]-[S371F] CC.1 184 88 47.8% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CC.1 184 39 21.2% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,I870V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CC.1 184 30 16.3% 1 +[H69-,V70-,V213G,S221L,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CC.1 184 2 1.1% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,D1139Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CC.1 184 2 1.1% 1 +[H69-,V70-,T124N,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.67 184 160 87.0% 0 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.67 184 6 3.3% 1 +[T29I,C1247Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.67 184 4 2.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.67 184 3 1.6% 1 +[T29I,G75V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.67 184 2 1.1% 1 +[T29I,I584V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.8 183 128 69.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.8 183 13 7.1% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.8 183 6 3.3% 1 +[H69-,V70-,D178N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.8 183 5 2.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1124V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.8 183 3 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] GJ.5 183 116 63.4% 0 +[K182N,D253G,T478R,P521S]-[G252V,T478K] (consensus) GJ.5 183 8 4.4% 1 +[H146K,K182N,D253G,T478R,P521S]-[H146Q,G252V,T478K] GJ.5 183 4 2.2% 1 +[L5F,K182N,D253G,T478R,P521S]-[G252V,T478K] GJ.5 183 3 1.6% 2 +[H146K,A163V,K182N,D253G,T478R,P521S]-[H146Q,G252V,T478K] GJ.5 183 3 1.6% 3 +[K182N,D253G,T478R,A899S]-[G252V,K417N,T478K] BA.2.63 182 104 57.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.63 182 22 12.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.63 182 21 11.5% 1 +[V213G,G339D,Q493R,A879V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.63 182 13 7.1% 1 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.63 182 3 1.6% 2 +[I68T,V213G,G339D,Q493R,D1118H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] W.2 182 162 89.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) W.2 182 7 3.8% 1 +[A222V,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.2 182 4 2.2% 1 +[T20I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.2 182 3 1.6% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.2 182 2 1.1% 1 +[A222V,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.54 181 129 71.3% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.54 181 7 3.9% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.54 181 4 2.2% 1 +[L5F,H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.54 181 4 2.2% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,M1229I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.54 181 4 2.2% 1 +[H69-,V70-,K182Q,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.546 180 150 83.3% 0 +[L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.546 180 9 5.0% 1 +[L18F,L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.546 180 7 3.9% 1 +[T573I,L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.546 180 6 3.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.546 180 1 0.6% 1 +[L822F,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.43 180 97 53.9% 0 (consensus) XBB.1.5.43 180 37 20.6% 1 +[S494P] XBB.1.5.43 180 15 8.3% 2 +[H146K,S494P]-[H146Q] XBB.1.5.43 180 3 1.7% 1 +[E583D] XBB.1.5.43 180 3 1.7% 2 +[A262V,Q954D]-[Q954H] BF.41.1 180 100 55.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.41.1 180 49 27.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.41.1 180 4 2.2% 1 +[H69-,V70-,K187E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.41.1 180 4 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.41.1 180 2 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1248Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.189 180 124 68.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.189 180 24 13.3% 2 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.189 180 5 2.8% 1 +[N717S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.189 180 3 1.7% 1 +[H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.189 180 3 1.7% 1 +[V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FP.1 180 154 85.6% 0 +[A27-,H69-,V70-]-[L24-,A27S] (consensus) FP.1 180 4 2.2% 1 +[A27-,H69-,V70-,N703S]-[L24-,A27S] FP.1 180 3 1.7% 1 +[A27-,H69-,V70-,H146K]-[L24-,A27S,H146Q] FP.1 180 2 1.1% 1 +[A27-,H69-,V70-,G1267A]-[L24-,A27S] FP.1 180 2 1.1% 1 +[A27-,H69-,V70-]-[L24-,A27S,H146Q] B.1.605 180 128 71.1% 0 +[T1116N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.605 180 7 3.9% 1 +[T1116N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.605 180 6 3.3% 2 +[Q677H,T1116N,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.605 180 4 2.2% 1 +[T1116N,S1242I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.605 180 3 1.7% 1 +[A1020S,T1116N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FU.3 180 135 75.0% 0 +[E180V,T478R,T547I]-[T478K] (consensus) FU.3 180 6 3.3% 1 +[H146K,E180V,T478R,T547I]-[H146Q,T478K] FU.3 180 6 3.3% 1 +[E180V,T478R,T547I,E990D]-[T478K] FU.3 180 4 2.2% 1 +[E180V,T478R,T547I]-[Y144-,T478K] FU.3 180 2 1.1% 1 +[E180V,T478R,T547I]-[K417N,T478K] B.1.1.58 179 144 80.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.58 179 14 7.8% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.58 179 5 2.8% 1 +[I1225L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.58 179 3 1.7% 3 +[L18F,A688V,D936N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.58 179 2 1.1% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.174 179 98 54.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.174 179 21 11.7% 2 +[L18F,S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.174 179 10 5.6% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.174 179 7 3.9% 1 +[P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.174 179 7 3.9% 2 +[H49Y,E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.362 179 134 74.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.362 179 13 7.3% 1 +[Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.362 179 5 2.8% 1 +[G75V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.362 179 3 1.7% 1 +[A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.362 179 2 1.1% 1 +[A694V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.5 179 112 62.6% 0 +[D253G,F486S,Q613H]-[G252V,F486P] (consensus) XBB.2.5 179 10 5.6% 3 +[D253G,F486S,Q613H]-[G252V,R408S,S477N,F486P,Q954H] XBB.2.5 179 5 2.8% 1 +[D253G,F486S,Q613H,T961M]-[G252V,F486P] XBB.2.5 179 4 2.2% 1 +[F157L,D253G,F486S,Q613H]-[G252V,F486P] XBB.2.5 179 4 2.2% 1 +[D253G,F486S,Q613H]-[G142D,G252V,F486P] B.1.177.2 179 128 71.5% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.2 179 25 14.0% 1 +[A222V,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.2 179 11 6.1% 1 +[V143F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.2 179 6 3.4% 1 +[A222V,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.2 179 2 1.1% 1 +[G75V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.23 179 164 91.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.23 179 4 2.2% 1 +[T1027S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.23 179 2 1.1% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.23 179 2 1.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] B.23 179 2 1.1% 2 +[L5F,I1232V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KP.1.1 178 103 57.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KP.1.1 178 14 7.9% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.1.1 178 13 7.3% 1 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.1.1 178 11 6.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.1.1 178 3 1.7% 5 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.221.2 178 149 83.7% 0 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.221.2 178 9 5.1% 1 +[S98F,A520V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.2 178 4 2.2% 1 +[S98F,I1081F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.2 178 4 2.2% 1 +[S98F,S254Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.2 178 3 1.7% 1 +[S98F,V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.108 178 152 85.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.108 178 17 9.6% 1 +[S13I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.108 178 2 1.1% 1 +[E1111Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.108 178 1 0.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.108 178 1 0.6% 2 +[D405V,Q414A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.9 178 130 73.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.9 178 9 5.1% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,S477D,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,E484A,F490S,P681H] JN.9 178 6 3.4% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.9 178 4 2.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.9 178 2 1.1% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] DE.2 178 83 46.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DE.2 178 74 41.6% 5 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DE.2 178 3 1.7% 6 +[L5F,H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DE.2 178 3 1.7% 6 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] DE.2 178 3 1.7% 6 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V,S940F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.18 178 82 46.1% 0 +[F486S]-[F486P] (consensus) XBB.1.18 178 10 5.6% 1 +[F486S]-[R346T,F486P] XBB.1.18 178 8 4.5% 1 +[F486S]-[R408S,F486P] XBB.1.18 178 6 3.4% 1 +[H146K,F486S]-[H146Q,F486P] XBB.1.18 178 6 3.4% 1 +[F486S]-[K417N,F486P] B.1.258.9 177 165 93.2% 0 +[H69-,V70-,N439K,G1223S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.9 177 7 4.0% 1 +[L18F,H69-,V70-,N439K,G1223S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.9 177 1 0.6% 2 +[I68-,H69-,N439K,G1223S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.9 177 1 0.6% 1 +[H69-,V70-,N439K,A520S,G1223S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.9 177 1 0.6% 1 +[H69-,V70-,N439K,G1223S,G1246S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EJ.3 177 141 79.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) EJ.3 177 4 2.3% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.3 177 3 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,D215N,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.3 177 2 1.1% 1 +[N17S,K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.3 177 2 1.1% 1 +[K147E,W152R,F157L,P209L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] P.1.12.1 176 156 88.6% 0 +[L18F,T20N,P26S,D138Y,R190S,R246G,T284I,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.12.1 176 6 3.4% 1 +[L18F,T20N,P26S,D138Y,R190S,R246G,T284I,T299I,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.12.1 176 2 1.1% 1 +[L18F,T20N,P26S,D138Y,R190S,R246G,T284I,K417T,E484K,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.12.1 176 2 1.1% 4 +[L18F,T20N,P26S,D138Y,R246G,G261-,A264-,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.12.1 176 1 0.6% 1 +[L18F,T20N,P26S,D138Y,R190S,R246G,T259K,T284I,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] XBB.2.4 176 84 47.7% 0 +[D253G]-[G252V] (consensus) XBB.2.4 176 8 4.5% 1 +[D253G]-[G252V,K417N] XBB.2.4 176 7 4.0% 1 +[H146K,D253G]-[H146Q,G252V] XBB.2.4 176 7 4.0% 2 +[D253G]-[G142D,G252V,K417N] XBB.2.4 176 4 2.3% 1 +[A123V,D253G]-[G252V] HH.1.1 176 118 67.0% 0 +[G181A,G184V,D253G,P521S]-[G252V] (consensus) HH.1.1 176 13 7.4% 1 +[G181A,G184V,D253G,P521S,G1124V]-[G252V] HH.1.1 176 6 3.4% 1 +[G181A,G184V,D253G,P521S,Q804K]-[G252V] HH.1.1 176 5 2.8% 1 +[G181A,G184V,D253G,P521S,K795N]-[G252V] HH.1.1 176 4 2.3% 1 +[G181A,G184V,D253G,P521S,G1219V]-[G252V] BF.23 176 83 47.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.23 176 60 34.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.23 176 5 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[T19I,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.23 176 4 2.3% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V,A1020S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.23 176 2 1.1% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,S758G,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.171 175 158 90.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.171 175 12 6.9% 1 +[S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.171 175 1 0.6% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.171 175 1 0.6% 1 +[I818V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.171 175 1 0.6% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.69 175 140 80.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.69 175 17 9.7% 1 +[V213G,G339D,Q493R,D1259H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.69 175 3 1.7% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.69 175 1 0.6% 2 +[V213G,G339D,A435S,Q493R,D1259H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.69 175 1 0.6% 1 +[Q52H,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.2.8 175 116 66.3% 0 +[D253G,F486S]-[G252V,F486P] (consensus) XBB.2.8 175 5 2.9% 1 +[H146K,D253G,F486S]-[H146Q,G252V,F486P] XBB.2.8 175 5 2.9% 1 +[G219V,D253G,F486S]-[G252V,F486P] XBB.2.8 175 4 2.3% 1 +[L5F,D253G,F486S]-[G252V,F486P] XBB.2.8 175 4 2.3% 2 +[H146K,N148T,D253G,F486S]-[H146Q,G252V,F486P] B.1.218 175 129 73.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.218 175 10 5.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.218 175 4 2.3% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.218 175 3 1.7% 2 +[P809S,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.218 175 3 1.7% 1 +[V534I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] ET.1 175 131 74.9% 0 +[H69-,V70-,K147E,K182N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) ET.1 175 9 5.1% 1 +[H69-,V70-,K147E,K182N,V213G,G339D,K444T,L452R,A475V,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ET.1 175 7 4.0% 1 +[H69-,V70-,K147E,K182N,V213G,G339D,D420N,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ET.1 175 4 2.3% 1 +[H69-,V70-,K147E,K182N,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ET.1 175 3 1.7% 1 +[H69-,V70-,K147E,K182N,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EG.5 175 34 19.4% 0 +[Q14K,F456L,A522P] EG.5 175 22 12.6% 2 +[F456L] (consensus) EG.5 175 20 11.4% 3 +[F456L,N481K] EG.5 175 14 8.0% 3 +[Q52H,F456L] EG.5 175 12 6.9% 3 +[F456L,N679R]-[N679K] B.1.306 174 144 82.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.306 174 5 2.9% 1 +[N751K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.306 174 4 2.3% 1 +[A688S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.306 174 3 1.7% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.306 174 2 1.1% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.3.1 174 124 71.3% 0 +[D80Y,D253G,P521S]-[G252V] (consensus) XBB.2.3.1 174 12 6.9% 1 +[D80Y,D253G,P521S,L938F]-[G252V] XBB.2.3.1 174 6 3.4% 6 +[D80Y,E180D,G181-,K182-,Q183-,G184-,N185-,D253G,P521S]-[Q183E,G252V] XBB.2.3.1 174 3 1.7% 1 +[D80Y,H146K,D253G,P521S]-[H146Q,G252V] XBB.2.3.1 174 3 1.7% 1 +[L5F,D80Y,D253G,P521S]-[G252V] BA.3.1 174 154 88.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,K417T,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,R408S,K417N,V445P,N460K,F486P,F490S] (consensus) BA.3.1 174 6 3.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,K417T,Q493R,I670V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,R408S,K417N,V445P,N460K,F486P,F490S] BA.3.1 174 3 1.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,A222V,G339D,K417T,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,R408S,K417N,V445P,N460K,F486P,F490S] BA.3.1 174 3 1.7% 1 +[A67V,H69-,V70-,T76I,T95I,V143-,Y145-,N211-,L212I,G339D,K417T,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,R408S,K417N,V445P,N460K,F486P,F490S] BA.3.1 174 1 0.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,K417T,Q493R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,R408S,K417N,V445P,N460K,F486P,F490S,P681H] BA.2.85 174 74 42.5% 0 +[V213G,G339D,Q493R,I651V,A831T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.85 174 42 24.1% 1 +[V213G,G339D,Q493R,I651V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.85 174 38 21.8% 2 +[V213G,G339D,Q493R,T573I,I651V,A831T]-[V83A,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.85 174 9 5.2% 3 +[V213G,G339D,Q493R,T573I,I651V,Q677H,A831T]-[V83A,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.85 174 4 2.3% 2 +[L176F,V213G,G339D,Q493R,I651V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CL.1.3 173 103 59.5% 0 +[H69F,V70-,S71-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CL.1.3 173 18 10.4% 1 +[Q14H,H69F,V70-,S71-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CL.1.3 173 11 6.4% 1 +[H69F,V70-,S71-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] CL.1.3 173 4 2.3% 2 +[L5F,H69F,V70-,S71-,K150E,V213G,G339D,K444N,L452R,F486V,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CL.1.3 173 3 1.7% 1 +[H69F,V70-,S71-,K150E,V213G,G339D,K444N,L452R,F486V,L752F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.177.46 173 122 70.5% 0 +[A222V,A262S,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.46 173 29 16.8% 1 +[A222V,A262S,S939F,T941A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.46 173 9 5.2% 1 +[A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.46 173 4 2.3% 1 +[A222V,A262S,Q613H,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.46 173 2 1.2% 1 +[A222V,A262S,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] FL.21.2 173 122 70.5% 0 (consensus) FL.21.2 173 9 5.2% 1 -[Y144-] FL.21.2 173 3 1.7% 1 +[L1234I] FL.21.2 173 3 1.7% 1 +[L242F] FL.21.2 173 2 1.2% 1 -[K417N] ER.1 173 101 58.4% 0 +[H69-,V70-,V213G,S256P,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) ER.1 173 32 18.5% 1 +[V3I,H69-,V70-,V213G,S256P,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ER.1 173 20 11.6% 1 +[H69-,V70-,V213G,S256P,G339D,T385I,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ER.1 173 13 7.5% 2 +[V3I,H69-,V70-,V213G,S256P,G339D,K444T,L452R,F486V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ER.1 173 2 1.2% 1 +[H69-,V70-,V213G,S256P,G339D,K444T,L452R,F486V,H1159P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.177.85 172 121 70.3% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.85 172 13 7.6% 1 +[A222V,C1247F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.85 172 10 5.8% 1 +[V143F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.85 172 3 1.7% 1 +[A222V,K1181R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.85 172 3 1.7% 1 +[A222V,A570S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.9 172 155 90.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,I1232V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.9 172 6 3.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,N481K,F486S,I1232V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.9 172 2 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,A647S,I1232V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.9 172 2 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,G1085A,I1232V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.9 172 1 0.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,E340Q,K444T,L452R,F486S,I1232V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBB.1.5.26 172 130 75.6% 0 (consensus) XBB.1.5.26 172 6 3.5% 1 +[H146K]-[H146Q] XBB.1.5.26 172 4 2.3% 1 +[A570V] XBB.1.5.26 172 3 1.7% 2 +[D796H,A1020S]-[D796Y] XBB.1.5.26 172 2 1.2% 3 +[H146K]-[H146Q,R346T,K417N] B.1.580 171 120 70.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.580 171 12 7.0% 1 +[D427N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.580 171 6 3.5% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.580 171 5 2.9% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.580 171 4 2.3% 1 +[L585F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.30 171 155 90.6% 0 +[H69-,V70-,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.30 171 7 4.1% 1 +[H69-,V70-,T95I,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.30 171 4 2.3% 1 +[H69-,V70-,V213G,L249S,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.30 171 1 0.6% 2 +[H69-,V70-,V213G,L249S,G339D,K444T,V445A,L452R,P479L,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.30 171 1 0.6% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.1.181 170 146 85.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.181 170 14 8.2% 1 +[M900I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.181 170 4 2.4% 1 +[G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.181 170 2 1.2% 1 +[T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.181 170 1 0.6% 1 +[D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.9.4 170 136 80.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.9.4 170 5 2.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.9.4 170 4 2.4% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.9.4 170 3 1.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.9.4 170 3 1.8% 2 +[L5F,L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.3.3 170 123 72.4% 0 +[K147Q,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.3 170 9 5.3% 1 +[K147Q,W152R,F157L,I210V,V213G,D215G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.3 170 9 5.3% 1 +[K147Q,W152R,F157L,R190S,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.3 170 8 4.7% 1 +[K147Q,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.3.3 170 5 2.9% 1 +[K147Q,W152R,F157L,I210V,V213G,G257S,K356T,P812L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] C.36.3.1 169 83 49.1% 0 +[S12F,H69-,V70-,W152R,R346S,L452R,Q677H,A845S,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.36.3.1 169 43 25.4% 1 +[S12F,H69-,V70-,W152R,R346S,L452R,Q677H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3.1 169 15 8.9% 1 +[S12F,H69-,V70-,W152R,S221L,R346S,L452R,Q677H,A845S,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3.1 169 12 7.1% 1 +[S12F,H69-,V70-,W152R,G181V,R346S,L452R,Q677H,A845S,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3.1 169 2 1.2% 2 +[S12F,H69-,V70-,W152R,G181V,R346S,L452R,Q677H,A845S,A899S,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.16 168 129 76.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.16 168 17 10.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1229I,C1236F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.16 168 5 3.0% 1 +[T19R,R34L,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.16 168 2 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.16 168 2 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1229I,C1248Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.195 168 123 73.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.195 168 9 5.4% 2 +[R21I,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.195 168 7 4.2% 1 +[Q271R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.195 168 5 3.0% 1 +[E96Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.195 168 3 1.8% 1 +[L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.544 168 122 72.6% 0 +[P26L,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.544 168 14 8.3% 1 +[P26L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.544 168 6 3.6% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.544 168 4 2.4% 3 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.544 168 3 1.8% 1 +[P26L,Q675H,P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.4 168 141 83.9% 0 +[H69-,V70-,L189F,N439K,V772I,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.4 168 11 6.5% 1 +[L18F,H69-,V70-,L189F,N439K,V772I,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.4 168 5 3.0% 1 +[L5F,H69-,V70-,L189F,N439K,V772I,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.4 168 2 1.2% 1 +[H69-,V70-,L189F,S221L,N439K,V772I,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.4 168 2 1.2% 1 +[H69-,V70-,L189F,N439K,V772I,A783T,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.14 168 157 93.5% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.14 168 2 1.2% 1 +[A222V,T547I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.14 168 2 1.2% 1 +[A222V,A243S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.14 168 1 0.6% 1 +[A222V,K458N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.14 168 1 0.6% 1 +[S151I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.104 168 139 82.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.104 168 20 11.9% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.104 168 2 1.2% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.104 168 2 1.2% 1 +[M1237V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.104 168 1 0.6% 1 +[V90F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.38 168 78 46.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.38 168 56 33.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.38 168 8 4.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.38 168 4 2.4% 2 +[L5F,H69-,V70-,V127F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.38 168 3 1.8% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,P521S,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.46 168 159 94.6% 0 +[V213G,G339D,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.46 168 3 1.8% 1 +[V213G,S254F,G339D,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.46 168 2 1.2% 1 +[V213G,G339D,Q493R,D1153Y,C1236F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.46 168 1 0.6% 1 +[V213G,G339D,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.46 168 1 0.6% 1 +[V213G,G339D,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] ED.3 168 138 82.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,D843N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) ED.3 168 6 3.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S698L,D843N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.3 168 5 3.0% 1 +[H69-,V70-,G181V,V213G,G339D,K444T,L452R,F486V,D843N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.3 168 4 2.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,D843N,T1117I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.3 168 3 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,D843N]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.602 167 136 81.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.602 167 7 4.2% 1 +[D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.602 167 4 2.4% 1 +[D1199H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.602 167 3 1.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.602 167 2 1.2% 1 +[G142S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.201 167 93 55.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.201 167 31 18.6% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.201 167 11 6.6% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.201 167 11 6.6% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.201 167 8 4.8% 1 +[S689I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GS.3 167 132 79.0% 0 +[R190S,D253G,T478R,P521S]-[G252V,T478K] (consensus) GS.3 167 11 6.6% 3 +[R190S,G252-,+253G,T478R,P521S]-[G252V,T478K] GS.3 167 3 1.8% 1 +[R190S,D253G,T478R,P521S,S940F]-[G252V,T478K] GS.3 167 2 1.2% 1 +[R190S,D253G,T478R,P521S]-[G252V,K417N,T478K] GS.3 167 2 1.2% 1 +[R190S,D253G,T478R]-[G252V,T478K] B.1.1.219 166 82 49.4% 0 +[F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.219 166 22 13.3% 1 +[F157L,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.219 166 22 13.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.219 166 5 3.0% 1 +[F157L,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.219 166 4 2.4% 1 +[L18F,F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.15 166 83 50.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.15 166 11 6.6% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.15 166 4 2.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.15 166 4 2.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] JN.1.15 166 3 1.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] FK.1.2.1 166 79 47.6% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.2.1 166 38 22.9% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,T286I,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.2.1 166 8 4.8% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,T719S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.2.1 166 5 3.0% 2 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,T286I,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,S371F,V445P,F486P,F490S] FK.1.2.1 166 3 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EG.5.2.3 166 140 84.3% 0 +[F456L,S704L,N1178D] (consensus) EG.5.2.3 166 7 4.2% 1 +[F456L,S704L,N1178D,G1219C] EG.5.2.3 166 3 1.8% 1 +[F456L,S704L,D936N,N1178D] EG.5.2.3 166 2 1.2% 2 +[F456L,S704L,L752F,N1178D,G1219C] EG.5.2.3 166 1 0.6% 1 +[F456L,T478E,S704L,N1178D]-[T478K] FM.1 166 132 79.5% 0 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) FM.1 166 3 1.8% 1 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,S494P,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FM.1 166 3 1.8% 1 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,Q613H,Q804H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FM.1 166 3 1.8% 2 +[N30K,H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,Q613H,S698L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FM.1 166 2 1.2% 1 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,Q613H,T678I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FM.2 166 76 45.8% 0 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,G946R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) FM.2 166 22 13.3% 1 +[H69-,V70-,M153V,N185D,V213G,G339D,K444T,L452R,F486V,G946R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FM.2 166 17 10.2% 1 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,G946R,P1143S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FM.2 166 7 4.2% 3 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FM.2 166 6 3.6% 1 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V,G946R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EF.1.1.1 166 139 83.7% 0 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EF.1.1.1 166 8 4.8% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1.1.1 166 6 3.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,S943N]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1.1.1 166 2 1.2% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EF.1.1.1 166 1 0.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.47 165 96 58.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.47 165 18 10.9% 1 +[H1159Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.47 165 11 6.7% 2 +[A626S,P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.47 165 4 2.4% 2 +[T95I,H1159Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.47 165 4 2.4% 1 +[D198G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.30 165 107 64.8% 0 +[H69-,V70-,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.30 165 19 11.5% 1 +[H69-,V70-,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.30 165 13 7.9% 1 +[H69-,V70-,G75R,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.30 165 6 3.6% 2 +[H69-,V70-,F157L,V213G,G339D,Y351H,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.30 165 2 1.2% 1 +[H69-,V70-,W152L,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.177.50 165 119 72.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.50 165 10 6.1% 1 +[A222V,V1230L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.50 165 9 5.5% 1 +[A222V,G446V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.50 165 5 3.0% 1 +[A222V,S1252Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.50 165 3 1.8% 1 +[A222V,P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DV.5 165 138 83.6% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.5 165 2 1.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,I670V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.5 165 2 1.2% 1 +[H146N,K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.5 165 2 1.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,L1265I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.5 165 2 1.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,V622F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BQ.1.1.39 165 114 69.1% 0 +[H69-,V70-,K182E,V213G,Q218H,P251L,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.39 165 12 7.3% 1 +[H69-,V70-,K182E,V213G,Q218H,P251L,G339D,K444T,L452R,F486V,A829S,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.39 165 4 2.4% 1 +[H69-,V70-,D111N,K182E,V213G,Q218H,P251L,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.39 165 3 1.8% 2 +[L5F,H69-,V70-,K182E,V213G,Q218H,P251L,G339D,K444T,L452R,F486V,A829S,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.39 165 3 1.8% 1 +[H69-,V70-,K182E,V213G,Q218H,P251L,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BA.2.28 165 65 39.4% 0 +[V213G,G339D,L452R,Q493R,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.28 165 39 23.6% 3 +[V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.28 165 31 18.8% 2 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.28 165 15 9.1% 1 +[V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.28 165 4 2.4% 3 +[V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.60 165 93 56.4% 0 +[H146K,M177I]-[H146Q] (consensus) XBB.1.5.60 165 10 6.1% 3 +[Y144K,Y145-,H146-,M177I]-[Y144-,H146Q] XBB.1.5.60 165 6 3.6% 1 +[H146K,N148T,M177I]-[H146Q] XBB.1.5.60 165 6 3.6% 1 +[H146K,M177I,A653V]-[H146Q] XBB.1.5.60 165 5 3.0% 2 +[H146K,M177I]-[H146Q,R408S,S477N] XCL 165 112 67.9% 0 +[L455F,F456L,V511I,P1162S] (consensus) XCL 165 11 6.7% 1 +[L455F,F456L,V511I,E619D,P1162S] XCL 165 4 2.4% 1 +[L455F,F456L,V511I,P1162S]-[Y144-] XCL 165 3 1.8% 1 +[T259I,L455F,F456L,V511I,P1162S] XCL 165 2 1.2% 1 +[E340Q,L455F,F456L,V511I,P1162S] B.1.1.220 164 133 81.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.220 164 5 3.0% 1 +[S98P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.220 164 5 3.0% 2 +[S98P,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.220 164 3 1.8% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.220 164 2 1.2% 2 +[E180G,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.3 164 132 80.5% 0 +[A222V,M1229T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) W.3 164 20 12.2% 1 +[A222V,A1087S,M1229T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.3 164 2 1.2% 2 +[A222V,S256L,A1087S,M1229T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.3 164 1 0.6% 1 +[L5F,A222V,M1229T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.3 164 1 0.6% 2 +[T76I,A222V,A1087S,M1229T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.240 163 124 76.1% 0 +[K1073N,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.240 163 33 20.2% 1 +[K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.240 163 2 1.2% 1 +[D178N,K1073N,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.240 163 1 0.6% 1 +[K1073N,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.240 163 1 0.6% 1 +[I233V,K1073N,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.134 163 112 68.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.134 163 26 16.0% 1 +[L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.134 163 16 9.8% 1 +[T76I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.134 163 2 1.2% 1 +[T385A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.134 163 1 0.6% 2 +[L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.33 163 158 96.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.33 163 1 0.6% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.33 163 1 0.6% 1 +[V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.33 163 1 0.6% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.33 163 1 0.6% 1 +[P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.521 162 80 49.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.521 162 10 6.2% 2 +[Q675H,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.521 162 6 3.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.521 162 6 3.7% 1 +[A958S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.521 162 5 3.1% 1 +[C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1.2 162 111 68.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.25.1.2 162 9 5.6% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1.2 162 8 4.9% 1 +[T19R,E156G,F157-,R158-,P209L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1.2 162 5 3.1% 1 +[T19R,E156G,F157-,R158-,L452R,A522V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1.2 162 4 2.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BM.1.1.1 162 97 59.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BM.1.1.1 162 7 4.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BM.1.1.1 162 7 4.3% 8 +[K147E,S151N,W152R,F157L,+209V,N211G,L212-,V213-,G257S,A626S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BM.1.1.1 162 4 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,P631S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BM.1.1.1 162 3 1.9% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] GE.1.1 161 99 61.5% 0 +[N185I,F186-,D253G,T478R,P521S,E554K]-[G252V,T478K] (consensus) GE.1.1 161 9 5.6% 1 +[N185I,F186-,D253G,T478R,P521S,E554K,Q677H]-[G252V,T478K] GE.1.1 161 4 2.5% 1 +[N185I,F186-,D253G,T478R,P521S,E554K]-[Y144-,G252V,T478K] GE.1.1 161 3 1.9% 3 +[N185I,F186-,G219D,T250I,D253G,T478R,P521S,E554K]-[Q183E,G252V,T478K] GE.1.1 161 3 1.9% 1 +[T29I,N185I,F186-,D253G,T478R,P521S,E554K]-[G252V,T478K] BA.4.6.2 161 123 76.4% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.6.2 161 6 3.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,N460K,F486P,F490S] BA.4.6.2 161 6 3.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,N658I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.2 161 5 3.1% 1 +[H69-,V70-,V213G,R214H,G339D,V445A,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.2 161 5 3.1% 1 +[H69-,V70-,K182N,V213G,G339D,V445A,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.439 161 119 73.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.439 161 14 8.7% 1 +[D111N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.439 161 11 6.8% 1 +[V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.439 161 9 5.6% 2 +[D111N,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.439 161 2 1.2% 2 +[D111N,T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.521 161 91 56.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.521 161 26 16.1% 2 +[E96D,N710S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.521 161 9 5.6% 3 +[E96D,K558N,N710S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.521 161 6 3.7% 3 +[E96D,N710S,D1199Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.521 161 6 3.7% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.4.1.1 161 108 67.1% 0 +[H69-,V70-,P209L,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.4.1.1 161 21 13.0% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.1.1 161 15 9.3% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,L452R,F486V,S939F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.1.1 161 3 1.9% 1 +[H69-,V70-,P209L,V213G,S256L,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.1.1 161 2 1.2% 1 +[H69-,V70-,P209L,V213G,G339D,N354K,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] GU.1 161 126 78.3% 0 +[N481S,P521T,V772I] (consensus) GU.1 161 8 5.0% 1 +[K182R,N481S,P521T,V772I] GU.1 161 3 1.9% 1 +[N481S,P521T,V772I,G1124V] GU.1 161 2 1.2% 1 +[T19L,N481S,P521T,V772I]-[T19I] GU.1 161 2 1.2% 1 +[N481S,P521T,V772I]-[K417N] B.1.517.1 160 155 96.9% 0 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.517.1 160 2 1.2% 1 +[N501T,S884F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.517.1 160 1 0.6% 1 +[N501I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.517.1 160 1 0.6% 1 +[N501T,P1079S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.517.1 160 1 0.6% 1 +[A475S,N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.1 160 92 57.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5.1 160 44 27.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.1 160 2 1.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.1 160 2 1.2% 1 +[T19R,E156G,F157-,R158-,L452R,T547I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.1 160 2 1.2% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,H1101Q]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.573 160 156 97.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.573 160 1 0.6% 1 +[P26S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.573 160 1 0.6% 1 +[P1079S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.573 160 1 0.6% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.573 160 1 0.6% 1 +[E154Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CM.1 160 100 62.5% 0 +[N17S,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.1 160 14 8.8% 1 +[N17S,M153T,N164K,V213G,H245N,Y248H,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.1 160 8 5.0% 2 +[N17S,M153T,N164K,V213G,D215H,H245N,Y248H,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.1 160 7 4.4% 1 +[N17S,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,E484A,F486P,F490S] CM.1 160 4 2.5% 1 +[N17S,M153T,N164K,V213G,H245N,G257D,G339D,K444M,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BZ.2 159 130 81.8% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BZ.2 159 8 5.0% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BZ.2 159 6 3.8% 1 +[H69-,V70-,V213G,A262V,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BZ.2 159 3 1.9% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BZ.2 159 2 1.3% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JE.1 159 92 57.9% 0 +[K182N,D253G,N450D,T478R,P521S]-[G252V,T478K] (consensus) JE.1 159 9 5.7% 1 +[T95I,K182N,D253G,N450D,T478R,P521S]-[G252V,T478K] JE.1 159 7 4.4% 1 +[H146K,K182N,D253G,N450D,T478R,P521S]-[H146Q,G252V,T478K] JE.1 159 6 3.8% 1 +[T76I,K182N,D253G,N450D,T478R,P521S]-[G252V,T478K] JE.1 159 4 2.5% 1 +[K182N,D253G,N450D,T478R,P521S,A1020S]-[G252V,T478K] GY.7 159 111 69.8% 0 +[E180V,T478R]-[T478K] (consensus) GY.7 159 5 3.1% 1 +[E180V,T478R]-[K417N,T478K] GY.7 159 4 2.5% 1 +[E180V,T478R]-[R408S,T478K] GY.7 159 4 2.5% 1 +[E180V,D215G,T478R]-[T478K] GY.7 159 3 1.9% 1 +[E180V,T478R,S1147L]-[T478K] B.1.1.328 158 56 35.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.328 158 51 32.3% 1 +[E1258D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.328 158 5 3.2% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.328 158 5 3.2% 1 +[G257V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.328 158 4 2.5% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.274 158 62 39.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.274 158 44 27.8% 1 +[E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.274 158 12 7.6% 1 +[Q677K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.274 158 4 2.5% 2 +[V3G,E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.274 158 3 1.9% 2 +[H49Y,Q677K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] K.3 158 155 98.1% 0 +[A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) K.3 158 2 1.3% 2 +[S98F,A626S,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] K.3 158 1 0.6% 1 +[A626S,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XDD.1.1 158 62 39.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDD.1.1 158 45 28.5% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD.1.1 158 9 5.7% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD.1.1 158 4 2.5% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] XDD.1.1 158 3 1.9% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BL.3 158 54 34.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BL.3 158 42 26.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.3 158 18 11.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,T761I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BL.3 158 4 2.5% 5 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S,N764K] BL.3 158 4 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,D1084Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BF.7.11 158 117 74.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,D1260Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.11 158 15 9.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1260Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.11 158 10 6.3% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,D1260Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.11 158 2 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S708A,D1260Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.11 158 2 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1260Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BV.1 158 131 82.9% 0 +[H69-,V70-,V213G,P251H,G339D,L452R,F486V,R1014K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BV.1 158 3 1.9% 1 +[H69-,V70-,V213G,P251H,G339D,L452R,F486V,R1014K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BV.1 158 2 1.3% 1 +[H69-,V70-,V213G,P251H,G339D,K444R,L452R,F486V,R1014K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BV.1 158 2 1.3% 1 +[H69-,V70-,V213G,P251H,G339D,L452R,F486V,R1014K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BV.1 158 2 1.3% 1 +[H69-,V70-,V213G,P251H,G339D,L452R,F486V,P812S,R1014K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] HP.1.1 158 64 40.5% 0 +[T478R]-[T478K] (consensus) HP.1.1 158 35 22.2% 1 +[T478R,E554K]-[T478K] HP.1.1 158 11 7.0% 3 +[Y145P,H146-,T478R]-[Y144-,H146Q,T478K] HP.1.1 158 7 4.4% 1 +[T478R]-[K417N,T478K] HP.1.1 158 3 1.9% 1 +[T478R,T547I]-[T478K] XAN 158 111 70.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAN 158 10 6.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAN 158 5 3.2% 1 +[H69-,V70-,N185D,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAN 158 4 2.5% 1 +[H69-,V70-,V213G,G339D,V445F,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAN 158 2 1.3% 1 +[H69-,V70-,N185S,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.4.1 158 127 80.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,G261V,K356T,T678I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.4.1 158 6 3.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G261V,K356T,T678I,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.1 158 4 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G261V,K356T,T678I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.4.1 158 3 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G261V,K356T,T678I,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.1 158 2 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G261V,K356T,S640F,T678I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBB.1.5.103 158 72 45.6% 0 +[E180D,G181-,K182-,Q183-,G184-,N185-,F456L]-[Q183E] (consensus) XBB.1.5.103 158 38 24.1% 1 +[E180D,G181-,K182-,Q183-,G184-,N185-,F456L,E554K]-[Q183E] XBB.1.5.103 158 4 2.5% 2 +[H146K,E180D,G181-,K182-,Q183-,G184-,N185-,F456L,E554K]-[H146Q,Q183E] XBB.1.5.103 158 3 1.9% 2 +[E180D,G181-,K182-,Q183-,G184-,N185-,F456L,E554K]-[Q183E,K417N] XBB.1.5.103 158 3 1.9% 1 +[E180D,G181-,K182-,Q183-,G184-,N185-,L455F,F456L]-[Q183E] B.1.397 157 84 53.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.397 157 26 16.6% 1 +[D1163V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.397 157 16 10.2% 1 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.397 157 6 3.8% 2 +[T572I,E1195D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.397 157 4 2.5% 1 +[F2L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.18 157 93 59.2% 0 +[K147E,W152R,F157L,K187T,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.18 157 22 14.0% 1 +[K147E,W152R,F157L,K182I,K187T,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.18 157 8 5.1% 1 +[K147E,W152R,F157L,K187T,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.18 157 3 1.9% 2 +[K147E,W152R,F157L,K187T,I210V,V213G,G257S,T323I,K444T,L452R,E484P,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S] CH.1.1.18 157 3 1.9% 4 +[K147E,W152R,F157L,K187T,I210V,V213G,G257S,K444T,L452R,F486S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.441 156 121 77.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.441 156 11 7.1% 2 +[A222V,G257V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.441 156 2 1.3% 1 +[G413R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.441 156 2 1.3% 2 +[H49Y,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.441 156 2 1.3% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.32 156 129 82.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.32 156 3 1.9% 2 +[T19L,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T778I,L858I]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.32 156 2 1.3% 2 +[K147E,W152R,F157L,I210V,V213G,+253F,G257-,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.32 156 2 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,V289I,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.32 156 1 0.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,L585F,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.199 156 125 80.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.199 156 22 14.1% 1 +[T791K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.199 156 2 1.3% 1 +[L948I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.199 156 1 0.6% 1 +[G257C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.199 156 1 0.6% 2 +[D574Y,D936A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.8 156 94 60.3% 0 +[F486S]-[G252V,F486P] (consensus) XBB.8 156 7 4.5% 1 +[F486S]-[H146Q,G252V,F486P] XBB.8 156 7 4.5% 1 +[K202R,F486S]-[G252V,F486P] XBB.8 156 4 2.6% 1 +[F486S]-[G252V,K417N,F486P] XBB.8 156 2 1.3% 1 +[V70L,F486S]-[G252V,F486P] EC.1 156 87 55.8% 0 +[H69-,V70-,H146L,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) EC.1 156 40 25.6% 2 +[H69-,V70-,Y145L,H146-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EC.1 156 12 7.7% 3 +[H69-,V70-,Y145L,H146-,G181A,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EC.1 156 3 1.9% 1 +[H69-,V70-,H146L,K150I,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EC.1 156 2 1.3% 3 +[H69-,V70-,Y145L,H146-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FL.17 156 91 58.3% 0 (consensus) FL.17 156 17 10.9% 1 +[H146K]-[H146Q] FL.17 156 6 3.8% 1 +[F157L] FL.17 156 3 1.9% 1 +[E96G] FL.17 156 2 1.3% 2 +[S689K,Q690-] XBC.1.6.4 156 124 79.5% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.6.4 156 4 2.6% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.4 156 4 2.6% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,S221L,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.4 156 3 1.9% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S255F,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6.4 156 2 1.3% 1 +[P25S,E156G,F157-,R158-,P209L,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] HF.1.2 156 110 70.5% 0 +[E180V,K304N,T478R,A688V]-[T478K] (consensus) HF.1.2 156 7 4.5% 1 +[E180V,K304N,T478R,Q675K,A688V]-[T478K] HF.1.2 156 7 4.5% 1 +[E180V,K304N,S477K,T478R,A688V]-[S477N,T478K] HF.1.2 156 3 1.9% 1 +[E180V,K304N,T478R,T676I,A688V]-[T478K] HF.1.2 156 2 1.3% 1 +[E180V,K304N,T478R,A688V,S1170Y]-[T478K] B.1.1.389 155 103 66.5% 0 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.389 155 11 7.1% 1 +[S255P,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.389 155 10 6.5% 1 +[V503I,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.389 155 4 2.6% 2 +[N439K,T1117I,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.389 155 3 1.9% 2 +[S255P,T1117I,E1195A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BM.2 155 52 33.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BM.2 155 32 20.6% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.2 155 11 7.1% 3 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.2 155 5 3.2% 6 +[K147E,W152R,F157L,Q183K,I210V,V213G,G257S,L452R,T478E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,F486P,F490S] BM.2 155 5 3.2% 5 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,T478E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,F486P,F490S] XBB.1.24.1 155 87 56.1% 0 +[L518Q] (consensus) XBB.1.24.1 155 30 19.4% 1 +[T307I,L518Q] XBB.1.24.1 155 6 3.9% 1 +[L518Q,I1221V] XBB.1.24.1 155 4 2.6% 2 +[T307I,F456L,L518Q] XBB.1.24.1 155 3 1.9% 1 +[M153I,L518Q] BN.1.11 155 130 83.9% 0 +[K147E,W152R,F157L,L176F,I210V,V213G,G257S,K356T,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.11 155 3 1.9% 1 +[R21T,K147E,W152R,F157L,L176F,I210V,V213G,G257S,K356T,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.11 155 2 1.3% 1 +[K147E,W152R,F157L,L176F,I210V,V213G,G257S,K356T,T618I,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.11 155 2 1.3% 1 +[K147E,W152R,F157L,L176F,I210V,V213G,G257S,T307I,K356T,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.11 155 2 1.3% 4 +[L176F,I210V,V213G,G257S,K356T,D936H]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FK.1 155 116 74.8% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1 155 5 3.2% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,M1050I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1 155 4 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,E1188D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1 155 4 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444M,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1 155 3 1.9% 1 +[K147E,W152R,F157L,E180K,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.43.5 154 126 81.8% 0 +[T19R,E156G,F157-,R158-,L452R,N501S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.5 154 15 9.7% 1 +[T19R,E156G,F157-,R158-,L452R,N501S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.5 154 2 1.3% 1 +[T19R,E156G,F157-,R158-,S359R,L452R,N501S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.5 154 1 0.6% 1 +[T19R,S151I,E156G,F157-,R158-,L452R,N501S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.5 154 1 0.6% 1 +[T19R,E156G,F157-,R158-,L452R,N501S,P681R,T716I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CM.4.1 154 91 59.1% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478R,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] (consensus) CM.4.1 154 30 19.5% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478R,E484R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] CM.4.1 154 6 3.9% 1 +[L5F,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478R,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] CM.4.1 154 3 1.9% 1 +[M153T,N164K,T208M,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478R,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] CM.4.1 154 2 1.3% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478R,E484R,A684V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] B.1.599 153 126 82.4% 0 +[M153I,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.599 153 7 4.6% 1 +[M153I,F565L,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.599 153 6 3.9% 2 +[M153I,V213L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.599 153 2 1.3% 1 +[M153I,D574N,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.599 153 1 0.7% 2 +[M153I,A243-,L244-,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.29 153 136 88.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.29 153 4 2.6% 1 +[P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.29 153 3 2.0% 1 +[D1165G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.29 153 2 1.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.29 153 1 0.7% 1 +[K814E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.315 153 137 89.5% 0 +[N856S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.315 153 3 2.0% 1 +[G75V,N856S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.315 153 2 1.3% 1 +[N658K,N856S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.315 153 2 1.3% 1 +[R346G,N856S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.315 153 2 1.3% 1 +[G769V,N856S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.28 153 135 88.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.28 153 5 3.3% 1 +[L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.28 153 2 1.3% 1 +[E702Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.28 153 2 1.3% 1 +[T240I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.28 153 1 0.7% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DV.2 153 107 69.9% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I569V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.2 153 27 17.6% 1 +[H69Y,K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I569V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.2 153 9 5.9% 1 +[K147E,W152R,F157L,Q183K,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I569V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.2 153 3 2.0% 2 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,N460T,F486S,I569V,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,N460K,F486P,F490S] DV.2 153 1 0.7% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I569V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.5 153 127 83.0% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.5 153 3 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,I569V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.5 153 2 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.5 153 2 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,Y473H,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.5 153 1 0.7% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,P631S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FL.18.1 153 110 71.9% 0 (consensus) FL.18.1 153 7 4.6% 1 +[D80H] FL.18.1 153 6 3.9% 1 +[E1207D] FL.18.1 153 6 3.9% 1 +[M153V] FL.18.1 153 5 3.3% 1 +[H146K]-[H146Q] CJ.1.3.2 153 131 85.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) CJ.1.3.2 153 6 3.9% 2 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,N556K,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3.2 153 4 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,N354K,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3.2 153 2 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P] CJ.1.3.2 153 1 0.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D428H,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] JG.2 152 115 75.7% 0 +[Q52H,G75V,F456L] (consensus) JG.2 152 7 4.6% 1 +[Q52H,G75V,R190S,F456L] JG.2 152 4 2.6% 1 +[Q52H,G75V,F456L,H1159Y] JG.2 152 2 1.3% 2 +[Q52H,G75V,T95I,F456L,P681R]-[P681H] JG.2 152 2 1.3% 1 +[Q52H,G75V,F456L,Q1180K] B.1.1.196 152 97 63.8% 0 +[D198G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.196 152 36 23.7% 1 +[D198G,K558N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.196 152 6 3.9% 2 +[L5F,D198G,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.196 152 4 2.6% 1 +[T95I,D198G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.196 152 3 2.0% 1 +[A67S,D198G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FR.1.3 152 133 87.5% 0 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) FR.1.3 152 1 0.7% 3 +[L5F,R78K,K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,S673I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.3 152 1 0.7% 1 +[L5F,K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.3 152 1 0.7% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,V963I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.3 152 1 0.7% 1 +[K147E,W152R,F157L,G181V,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBF.6 152 110 72.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.6 152 12 7.9% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.6 152 2 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,R408N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P] XBF.6 152 2 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,S884F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.6 152 2 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,V1230L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.4 152 113 74.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.4 152 11 7.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G446T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S] XBF.4 152 5 3.3% 1 +[K147E,W152R,F157L,I210V,V213G,I233V,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.4 152 3 2.0% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,G446T,K854N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S] XBF.4 152 2 1.3% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,G446T,E554K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S] CH.1.1.17 152 106 69.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.17 152 11 7.2% 2 +[V90I,K147E,W152R,F157L,G184V,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.17 152 6 3.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,S640F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.17 152 6 3.9% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.17 152 5 3.3% 3 +[V90I,K147E,W152R,F157L,G184V,I210V,V213G,G257S,K444T,L452R,F486S,Q677K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBB.1.5.44 152 96 63.2% 0 +[K356T,T572I] (consensus) XBB.1.5.44 152 24 15.8% 1 +[M177I,K356T,T572I] XBB.1.5.44 152 4 2.6% 1 +[K356T,T572I,P793S] XBB.1.5.44 152 3 2.0% 1 +[K356T,T572I]-[K417N] XBB.1.5.44 152 2 1.3% 1 +[W152L,K356T,T572I] BA.5.2.11 152 59 38.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.11 152 44 28.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.11 152 34 22.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.11 152 4 2.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1124V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.11 152 2 1.3% 3 +[H69-,V70-,V213G,G261V,G339D,L452R,F486V,E702K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.3.3 151 115 76.2% 0 (consensus) FL.3.3 151 12 7.9% 4 +[F186L,T573I,E583D,M1229T] FL.3.3 151 5 3.3% 3 +[F186L,E583D,M1229T] FL.3.3 151 2 1.3% 1 +[E154Q] FL.3.3 151 2 1.3% 1 +[S596I] FS.1 150 46 30.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FS.1 150 31 20.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,L858I,M1229I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FS.1 150 20 13.3% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,L858I,K1154R,M1229I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FS.1 150 12 8.0% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,L858I,V860L,M1229I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FS.1 150 4 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,S221L,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.5 150 105 70.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.5 150 17 11.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.5 150 12 8.0% 1 +[I68T,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.5 150 3 2.0% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,L858I,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.5 150 3 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,K921R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.128 150 113 75.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.128 150 6 4.0% 1 +[E406Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.128 150 5 3.3% 1 +[G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.128 150 4 2.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.128 150 3 2.0% 1 +[C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.205 150 141 94.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.205 150 3 2.0% 1 +[E918G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.205 150 1 0.7% 1 +[D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.205 150 1 0.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.205 150 1 0.7% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.465 150 131 87.3% 0 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.465 150 14 9.3% 1 +[L18F,A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.465 150 1 0.7% 1 +[A684V,A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.465 150 1 0.7% 2 +[A694V,A879S,F1121L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.465 150 1 0.7% 1 +[A879S,S929I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FT.3.1.1 150 97 64.7% 0 +[Q52H,A348S,T478R,D1168H]-[T478K] (consensus) FT.3.1.1 150 13 8.7% 1 +[Q52H,A348S,D389N,T478R,D1168H]-[T478K] FT.3.1.1 150 4 2.7% 1 +[Q52H,H146K,A348S,T478R,D1168H]-[H146Q,T478K] FT.3.1.1 150 4 2.7% 7 +[Q52H,P139Q,F140-,L141-,G142-,V143-,Y145-,H146-,A348S,T478R,D1168H]-[G142D,H146Q,T478K] FT.3.1.1 150 3 2.0% 1 +[Q52H,A348S,T478R,D1168H]-[K417N,T478K] BF.7.13.2 150 69 46.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.13.2 150 31 20.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.13.2 150 7 4.7% 3 +[H69-,V70-,V213G,L244F,H245-,G339D,L452R,F486V,A653V,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.13.2 150 6 4.0% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.13.2 150 6 4.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.32 150 135 90.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.32 150 3 2.0% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.32 150 3 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.32 150 2 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.32 150 1 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N1158S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.365 150 137 91.3% 0 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.365 150 4 2.7% 1 +[R21I,I693V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.365 150 4 2.7% 1 +[R21I,G261V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.365 150 2 1.3% 1 +[R21I,E661D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.365 150 1 0.7% 1 +[R21I,A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.70 149 72 48.3% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.70 149 69 46.3% 1 +[A222V,A647S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.70 149 2 1.3% 2 +[A222V,A647S,A989S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.70 149 2 1.3% 1 +[A222V,P621S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.70 149 1 0.7% 1 +[A222V,S1261F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.549 149 116 77.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.549 149 16 10.7% 1 +[G1246S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.549 149 2 1.3% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.549 149 1 0.7% 1 +[L1203I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.549 149 1 0.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.11 149 86 57.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.11 149 11 7.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.11 149 6 4.0% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.11 149 4 2.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1153H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.11 149 3 2.0% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,Y489H,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] EG.2.2 149 118 79.2% 0 +[K304N,T478R]-[T478K] (consensus) EG.2.2 149 4 2.7% 1 +[K304N,T478R,L922F]-[T478K] EG.2.2 149 4 2.7% 1 +[K304N,T478R,C1250F]-[T478K] EG.2.2 149 2 1.3% 1 +[K304N,T478R,T716I]-[T478K] EG.2.2 149 2 1.3% 2 +[L242F,K304N,E406Q,T478R]-[T478K] AV.1 149 141 94.6% 0 +[D80G,T95I,N439K,E484K,I1130V,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AV.1 149 5 3.4% 1 +[D80G,T95I,N439K,E484K,I1130V,D1139Y]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AV.1 149 1 0.7% 1 +[D80G,T95I,N439K,E484K,A647S,I1130V,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AV.1 149 1 0.7% 1 +[D80G,T95I,N439K,E484K,A623V,I1130V,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AV.1 149 1 0.7% 1 +[D80G,T95I,N439K,E484K,A688V,I1130V,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XR 149 147 98.7% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XR 149 1 0.7% 1 +[V213G,G339D,Q493R,D936N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XR 149 1 0.7% 1 +[V213G,G339D,Q493R,G885S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FT.3 149 95 63.8% 0 +[Q52H] (consensus) FT.3 149 19 12.8% 1 +[Q52H,D215H] FT.3 149 5 3.4% 2 +[Q52H,I418V,Q1071K] FT.3 149 5 3.4% 1 +[Q52H,H146K]-[H146Q] FT.3 149 3 2.0% 1 +[Q52H]-[K417N] EG.1.4.1 149 124 83.2% 0 +[P217L,Q613H] (consensus) EG.1.4.1 149 4 2.7% 1 +[L5F,P217L,Q613H] EG.1.4.1 149 3 2.0% 1 +[H146K,P217L,Q613H]-[H146Q] EG.1.4.1 149 2 1.3% 1 +[P217L,D228H,Q613H] EG.1.4.1 149 2 1.3% 1 +[P217L,A352S,Q613H] FL.1.2 149 102 68.5% 0 +[A701V] (consensus) FL.1.2 149 13 8.7% 1 +[H245Y,A701V] FL.1.2 149 5 3.4% 1 +[T323I,A701V] FL.1.2 149 3 2.0% 1 +[R214L,A701V] FL.1.2 149 2 1.3% 1 +[H146K,A701V]-[H146Q] BQ.1.10.3 148 125 84.5% 0 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.10.3 148 5 3.4% 1 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10.3 148 4 2.7% 1 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,F486P,F490S] BQ.1.10.3 148 2 1.4% 2 +[H69-,V70-,K147E,V213G,G257S,G339D,K444T,L452R,F486V,T500A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10.3 148 1 0.7% 2 +[H69-,V70-,K147E,V213G,G339D,T385I,K444T,L452R,F486V,N556-]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBQ 148 124 83.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBQ 148 5 3.4% 1 +[K147E,W152R,F157L,G181R,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBQ 148 3 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,C1236F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBQ 148 3 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T761I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBQ 148 2 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBB.1.37.1 148 75 50.7% 0 (consensus) XBB.1.37.1 148 14 9.5% 1 +[H245Y] XBB.1.37.1 148 9 6.1% 2 +[F456L,T478R]-[T478K] XBB.1.37.1 148 5 3.4% 1 -[R408S] XBB.1.37.1 148 4 2.7% 1 +[T478R]-[T478K] C.2.1 147 128 87.1% 0 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.2.1 147 6 4.1% 1 +[N501T,K835R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.2.1 147 2 1.4% 1 +[N501T,A871V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.2.1 147 2 1.4% 1 +[S155I,N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.2.1 147 1 0.7% 1 +[I326V,N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.15 147 129 87.8% 0 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.15 147 2 1.4% 1 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BA.2.15 147 2 1.4% 2 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S,H655Y] BA.2.15 147 1 0.7% 1 +[W64L,V213G,G261S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.15 147 1 0.7% 1 +[L5F,W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.112 147 133 90.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.112 147 5 3.4% 1 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.112 147 2 1.4% 1 +[Q14H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.112 147 2 1.4% 1 +[A647S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.112 147 1 0.7% 3 +[R408K,D936Y,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102.1 147 86 58.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.102.1 147 23 15.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,S689I,D950N,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102.1 147 6 4.1% 1 +[T19R,T95I,E156G,F157-,R158-,I233V,L452R,P681R,D950N,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102.1 147 6 4.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102.1 147 3 2.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q675K,P681R,D950N,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.525 147 45 30.6% 0 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.525 147 27 18.4% 1 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.525 147 10 6.8% 1 +[S98F,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.525 147 9 6.1% 2 +[E484K,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.525 147 8 5.4% 1 +[L5F,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.421 147 137 93.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.421 147 2 1.4% 1 +[T1273S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.421 147 1 0.7% 1 +[I693F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.421 147 1 0.7% 1 +[V642L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.421 147 1 0.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.6.3 147 91 61.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.6.3 147 22 15.0% 1 +[H69-,V70-,H146Y,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.3 147 11 7.5% 2 +[H69-,V70-,H146Y,V213G,G339D,L452R,F486V,G1267E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.3 147 4 2.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.3 147 2 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] P.4 147 76 51.7% 0 +[G142V,N164K,Q173K,L452R,S704L,I720V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.4 147 15 10.2% 1 +[G142V,N164K,Q173K,R346S,L452R,S704L,I720V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.4 147 14 9.5% 1 +[G142V,N164K,Q173K,L452R,A653V,S704L,I720V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.4 147 7 4.8% 2 +[N164K,Q173K,R346S,L452R,S704L,I720V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.4 147 7 4.8% 1 +[N164K,Q173K,L452R,S704L,I720V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.20 146 71 48.6% 0 +[H69-,V70-,V213G,G339D,A348S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.20 146 28 19.2% 1 +[L5F,H69-,V70-,V213G,G339D,A348S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.20 146 18 12.3% 1 +[H69-,V70-,V213G,G339D,A348S,I410V,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.20 146 6 4.1% 3 +[L5F,H69-,V70-,S98F,K147N,V213G,G339D,A348S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.20 146 3 2.1% 2 +[L5F,H69-,V70-,V213G,G339D,A348S,K444T,L452R,F486V,E583D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.1.251 146 111 76.0% 0 +[D111N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.251 146 20 13.7% 1 +[D111N,D215H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.251 146 3 2.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.251 146 2 1.4% 3 +[G75S,A684V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.251 146 2 1.4% 2 +[L5F,D111N,D215H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.285 146 116 79.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.285 146 12 8.2% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.285 146 4 2.7% 1 +[Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.285 146 3 2.1% 1 +[T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.285 146 1 0.7% 1 +[T1027N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.170 146 71 48.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.170 146 38 26.0% 2 +[D80H,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.170 146 9 6.2% 1 +[D80H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.170 146 5 3.4% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.170 146 2 1.4% 3 +[D80H,E309Q,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.41 146 76 52.1% 0 +[L335S,R403K] (consensus) XBB.1.41 146 14 9.6% 1 +[L335S,R403K,G1219V] XBB.1.41 146 14 9.6% 1 +[L335S,R403K,S494P] XBB.1.41 146 4 2.7% 2 +[Q14K,L335S,R403K,T478R]-[T478K] XBB.1.41 146 3 2.1% 4 +[L335S,R403K,G476-,T478N,+478K]-[S477N,T478K] XZ 146 116 79.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XZ 146 18 12.3% 1 +[V213G,G339D,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XZ 146 6 4.1% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XZ 146 1 0.7% 2 +[V213G,G339D,Q493R,C1253Y,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XZ 146 1 0.7% 1 +[V213G,G339D,Q493R,S884F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.90 146 114 78.1% 0 +[P621S] (consensus) XBB.1.5.90 146 3 2.1% 1 +[P621S,E1202K] XBB.1.5.90 146 3 2.1% 1 +[P621S]-[T19I] XBB.1.5.90 146 3 2.1% 2 +[D574Y,P621S,G1124V] XBB.1.5.90 146 3 2.1% 1 +[P621S,I1114T] JA.1 146 102 69.9% 0 +[D253G,F456L,P521S]-[G252V] (consensus) JA.1 146 9 6.2% 2 +[D253G,R273S,F456L,P521S,A688V]-[G252V] JA.1 146 7 4.8% 1 +[D253G,F456L,P521S,A688V]-[G252V] JA.1 146 4 2.7% 1 +[H146K,D253G,F456L,P521S]-[H146Q,G252V] JA.1 146 4 2.7% 1 +[D253G,F456L,P521S,A694V]-[G252V] B.12 145 141 97.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.12 145 1 0.7% 1 +[I105V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.12 145 1 0.7% 1 +[R1107M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.12 145 1 0.7% 1 +[D950Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.12 145 1 0.7% 1 +[A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.31 145 95 65.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,+1248C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.31 145 17 11.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.31 145 4 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,+1248C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.31 145 4 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,+1248C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.31 145 3 2.1% 2 +[H69-,V70-,V213G,D215Y,G339D,L452R,F486V,K558N,+1248C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.44 145 84 57.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.44 145 16 11.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.44 145 5 3.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.44 145 3 2.1% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.44 145 2 1.4% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BF.35 145 136 93.8% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.35 145 2 1.4% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,P1079S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.35 145 1 0.7% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.35 145 1 0.7% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,A1020T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.35 145 1 0.7% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.160.15 144 132 91.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.15 144 5 3.5% 1 +[L585I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.15 144 3 2.1% 1 +[P631S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.15 144 1 0.7% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.15 144 1 0.7% 1 +[N710S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.487 144 58 40.3% 0 +[T22I,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.487 144 58 40.3% 1 +[T22I,T385I,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.487 144 10 6.9% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.487 144 4 2.8% 2 +[T22I,T385I,L452R,S1252P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.487 144 2 1.4% 1 +[T22I,A411S,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.70 144 86 59.7% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.70 144 27 18.8% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.70 144 7 4.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.70 144 4 2.8% 1 +[S151I,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.70 144 4 2.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] JN.1.41 144 107 74.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.41 144 9 6.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.41 144 8 5.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1252F,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.41 144 2 1.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] JN.1.41 144 2 1.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1078T,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BN.1.2.7 144 93 64.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.7 144 11 7.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P] BN.1.2.7 144 4 2.8% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.7 144 2 1.4% 1 +[K147E,W152R,F157L,I210V,N211S,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.7 144 2 1.4% 3 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T638I,T791I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P] B.1.1.142 143 123 86.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.142 143 5 3.5% 3 +[S13I,S50L,V620I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.142 143 2 1.4% 1 +[A222T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.142 143 2 1.4% 1 +[Q239K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.142 143 1 0.7% 1 +[I1114T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.626 143 119 83.2% 0 +[L18F,A67-,I68-,H69-,G257S,E484K,N501T,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.626 143 9 6.3% 1 +[L18F,A67-,I68-,H69-,E484K,N501T,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.626 143 2 1.4% 1 +[L5F,L18F,A67-,I68-,H69-,G257S,E484K,N501T,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.626 143 2 1.4% 2 +[L18F,A67-,I68-,H69-,E484K,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.626 143 1 0.7% 4 +[L18F,G257S,E484K,N501T,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.10.3 143 112 78.3% 0 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.10.3 143 9 6.3% 1 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.10.3 143 3 2.1% 4 +[I68T,V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.3 143 2 1.4% 1 +[I68T,V213G,G339D,Q493R,T573I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.3 143 2 1.4% 1 +[I68T,V213G,Y248H,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.4.5 143 108 75.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.4.5 143 8 5.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.5 143 6 4.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.5 143 4 2.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N603S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.5 143 3 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L822F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.1.226 143 127 88.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.226 143 4 2.8% 1 +[S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.226 143 4 2.8% 2 +[L54F,E154Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.226 143 2 1.4% 1 +[F855S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.226 143 1 0.7% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.23 143 132 92.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.23 143 5 3.5% 1 +[A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.23 143 3 2.1% 1 +[E1202K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.23 143 1 0.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.23 143 1 0.7% 1 +[F32S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.6 143 136 95.1% 0 +[A829T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.6 143 5 3.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.6 143 1 0.7% 1 +[A829T,E1150D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.6 143 1 0.7% 1 +[S205T,A829T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GZ.1 143 72 50.3% 0 +[F186L,D253G,T478Q,P521S]-[G252V,T478K] (consensus) GZ.1 143 24 16.8% 1 +[F186L,D253G,T478Q,P521S,V1129I]-[G252V,T478K] GZ.1 143 16 11.2% 2 +[F186L,D253G,T478Q,P521S,T768S,V1129I]-[G252V,T478K] GZ.1 143 4 2.8% 1 +[T19L,F186L,D253G,T478Q,P521S]-[T19I,G252V,T478K] GZ.1 143 4 2.8% 1 +[F186L,D198G,D253G,T478Q,P521S]-[G252V,T478K] XCP 143 108 75.5% 0 +[L455F,F456L,A475V] (consensus) XCP 143 10 7.0% 1 +[L455F,F456L,A475V]-[Y144-] XCP 143 4 2.8% 1 +[E154Q,L455F,F456L,A475V] XCP 143 3 2.1% 1 +[F157L,L455F,F456L,A475V] XCP 143 1 0.7% 4 +[L5F,Y145P,H146-,L455F,F456L,A475V]-[Y144-,H146Q] BV.2 143 89 62.2% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BV.2 143 9 6.3% 5 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BV.2 143 7 4.9% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BV.2 143 5 3.5% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BV.2 143 3 2.1% 1 +[L5F,H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EG.5.1.7 143 111 77.6% 0 +[Q52H,K278N,F456L] (consensus) EG.5.1.7 143 2 1.4% 1 +[Q52H,H146K,K278N,F456L]-[H146Q] EG.5.1.7 143 2 1.4% 1 +[Q52H,K278N,F456L]-[R408S] EG.5.1.7 143 2 1.4% 1 +[Q52H,K278N,F456L]-[Y144-] EG.5.1.7 143 2 1.4% 1 +[Q52H,K278N,F456L,N481K] XBL.2 142 98 69.0% 0 (consensus) XBL.2 142 8 5.6% 1 +[E583D] XBL.2 142 6 4.2% 1 +[T323I] XBL.2 142 3 2.1% 1 -[V83A] XBL.2 142 2 1.4% 1 +[S691F] BN.1.4.2 142 95 66.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q1113K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.4.2 142 11 7.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,E281A,K356T,Q1113K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.2 142 5 3.5% 1 +[K97T,K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q1113K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.2 142 3 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q1113K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.4.2 142 3 2.1% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q1113K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FJ.1 142 119 83.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FJ.1 142 9 6.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356R,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FJ.1 142 3 2.1% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T1027S,H1159R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FJ.1 142 3 2.1% 1 +[K147E,W152R,F157L,F186L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FJ.1 142 1 0.7% 1 +[R78K,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BG.4 141 122 86.5% 0 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BG.4 141 9 6.4% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BG.4 141 4 2.8% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BG.4 141 1 0.7% 2 +[V213G,G339D,L452Q,Q493R,S704L,A899S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BG.4 141 1 0.7% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.31 141 111 78.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.31 141 6 4.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] B.31 141 5 3.5% 1 +[C1247F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.31 141 4 2.8% 1 +[T1066N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.31 141 3 2.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.10 141 64 45.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.10 141 9 6.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,T547K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.10 141 8 5.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.10 141 6 4.3% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.10 141 4 2.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.309 141 128 90.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.309 141 8 5.7% 1 +[D198G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.309 141 2 1.4% 1 +[Y28H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.309 141 1 0.7% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.309 141 1 0.7% 1 +[T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FY.4.2 141 64 45.4% 0 +[Y200C,L212S,Y451H] (consensus) FY.4.2 141 29 20.6% 1 +[L5F,Y200C,L212S,Y451H] FY.4.2 141 12 8.5% 1 +[Y200C,Y451H] FY.4.2 141 10 7.1% 2 +[Y200C,L212S,Y451H,K528R,M1237V] FY.4.2 141 4 2.8% 1 +[Y200C,L212S,Y451H]-[K417N] B.1.1.229 140 131 93.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.229 140 1 0.7% 1 +[S514F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.229 140 1 0.7% 1 +[L452M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.229 140 1 0.7% 1 +[H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.229 140 1 0.7% 4 +[L141-,G142-,V143-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.1 140 72 51.4% 0 +[L141-,G142-,V143-,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2.5.1 140 18 12.9% 1 +[L141-,G142-,V143-,D215A,+215AGY,L452R,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.1 140 6 4.3% 1 +[L141-,G142-,V143-,L176F,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.1 140 4 2.9% 1 +[L141-,G142-,V143-,D215A,+215AGY,L452R,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.1 140 3 2.1% 3 +[D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.3.4 140 70 50.0% 0 +[D253G,T478Q,P521S]-[G252V,T478K] (consensus) XBB.2.3.4 140 10 7.1% 1 +[D253G,T478Q,P521S]-[G252V,K417N,T478K] XBB.2.3.4 140 5 3.6% 1 +[D253G,T478Q,P521S,A701V]-[G252V,T478K] XBB.2.3.4 140 5 3.6% 1 +[D253G,T478Q,P521S,T961M]-[G252V,T478K] XBB.2.3.4 140 4 2.9% 2 +[R190T,D253G,T478Q,S494P,P521S]-[G252V,T478K] FB.1 140 79 56.4% 0 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) FB.1 140 21 15.0% 1 +[H69-,V70-,K182E,V213G,D253G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FB.1 140 16 11.4% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] FB.1 140 4 2.9% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,I666V,T998S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FB.1 140 3 2.1% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] B.1.595.1 139 120 86.3% 0 +[N1187Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.595.1 139 6 4.3% 1 +[N717T,N1187Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.1 139 2 1.4% 1 +[V6F,N1187Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.1 139 2 1.4% 1 +[S704L,N1187Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.1 139 2 1.4% 1 +[L5F,N1187Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DR.2 139 92 66.2% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] (consensus) DR.2 139 10 7.2% 1 +[H69-,V70-,V213G,L249S,G339D,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] DR.2 139 7 5.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V,A520S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] DR.2 139 4 2.9% 2 +[I68T,H69-,V70-,V213G,L249S,G339D,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] DR.2 139 3 2.2% 1 +[H69-,V70-,V213G,G339D,E340Q,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] FY.1.1 139 88 63.3% 0 +[V83S,Y200C]-[V83A] (consensus) FY.1.1 139 12 8.6% 1 +[V83S,Y200C,R408N]-[V83A,R408S] FY.1.1 139 3 2.2% 1 +[V83S,Q173R,Y200C]-[V83A] FY.1.1 139 3 2.2% 1 +[T19L,V83S,Y200C]-[T19I,V83A] FY.1.1 139 3 2.2% 3 +[V83S,Y145R,H146-,Y200C]-[V83A,Y144-,H146Q] XAH 139 123 88.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAH 139 3 2.2% 1 +[V213G,G339D,E340K,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAH 139 2 1.4% 1 +[G184D,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAH 139 1 0.7% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAH 139 1 0.7% 1 +[V213G,G339D,Q493R,M1237I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EC.1.1 139 77 55.4% 0 +[H69-,V70-,Y145L,H146-,V213G,G339D,K444T,V445A,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) EC.1.1 139 30 21.6% 1 +[H69-,V70-,Y145L,H146-,V213G,G339D,K444T,V445A,L452R,F486V,Q613H,I770M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EC.1.1 139 7 5.0% 1 +[H69-,V70-,Y145L,H146-,V213G,G339D,K444T,V445A,L452R,F486V,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EC.1.1 139 6 4.3% 1 +[H69-,V70-,Y145L,H146-,V213G,G339D,K444T,V445A,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] EC.1.1 139 4 2.9% 1 +[H69-,V70-,Y145L,H146-,V213G,G339D,K444T,V445A,L452R,F486A,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BF.40 138 113 81.9% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.40 138 8 5.8% 1 +[H69-,V70-,V213G,T286I,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.40 138 3 2.2% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BF.40 138 3 2.2% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.40 138 2 1.4% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,P809S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FQ.1 138 103 74.6% 0 +[H69-,V70-,K182E,V213G,Q218H,P251L,G339D,K444T,L452R,F486V,Q613H,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) FQ.1 138 9 6.5% 1 +[H69-,V70-,G75V,K182E,V213G,Q218H,P251L,G339D,K444T,L452R,F486V,Q613H,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FQ.1 138 9 6.5% 1 +[T19L,H69-,V70-,K182E,V213G,Q218H,P251L,G339D,K444T,L452R,F486V,Q613H,P1162L]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FQ.1 138 2 1.4% 1 +[H69-,V70-,K182E,V213G,Q218H,P251L,G339D,K444T,L452R,F486V,Q613H,T1120I,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FQ.1 138 2 1.4% 2 +[T19L,H69-,V70-,K182E,V213G,Q218H,A222S,P251L,G339D,K444T,L452R,F486V,Q613H,P1162L]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FD.3 138 54 39.1% 0 +[A348S] (consensus) FD.3 138 54 39.1% 1 +[D287H,A348S] FD.3 138 8 5.8% 1 +[A348S]-[K417N] FD.3 138 3 2.2% 1 +[G181V,A348S] FD.3 138 3 2.2% 2 +[A93S,A348S]-[K417N] B.1.162 137 124 90.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.162 137 7 5.1% 1 +[K97T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.162 137 2 1.5% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.162 137 1 0.7% 1 +[A653V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.162 137 1 0.7% 1 +[I203M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.9 137 103 75.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.9 137 12 8.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.9 137 4 2.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.9 137 2 1.5% 1 +[D178N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.9 137 2 1.5% 2 +[N657H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CA.5 137 111 81.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,A260D,F486S,Q613H,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CA.5 137 7 5.1% 1 +[K147E,W152R,F157L,K182N,I210V,V213G,G257S,A260D,F486S,Q613H,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.5 137 3 2.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,A260D,F486S,Q613H,T827I,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.5 137 2 1.5% 2 +[K147E,W152R,F157L,I210V,V213G,I235T,G257S,A260D,K356T,F486S,Q613H,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.5 137 2 1.5% 1 +[K147E,W152Q,F157L,I210V,V213G,G257S,A260D,F486S,Q613H,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JN.1.30 137 89 65.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.30 137 7 5.1% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.30 137 3 2.2% 1 +[+16MPLF,R21T,T29N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.30 137 3 2.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.30 137 2 1.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.366 137 100 73.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.366 137 8 5.8% 1 +[Q957L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.366 137 4 2.9% 2 +[A262S,C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.366 137 3 2.2% 1 +[I101-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.366 137 3 2.2% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.138 137 107 78.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.138 137 6 4.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.138 137 5 3.6% 1 +[I818V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.138 137 4 2.9% 1 +[T676I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.138 137 3 2.2% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KS.1 136 96 70.6% 0 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KS.1 136 7 5.1% 10 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KS.1 136 6 4.4% 4 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KS.1 136 3 2.2% 1 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,V642A,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KS.1 136 2 1.5% 2 +[+16MPLF,R21-,+22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.157 136 97 71.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.157 136 17 12.5% 1 +[A879T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.157 136 11 8.1% 1 +[W258L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.157 136 2 1.5% 2 +[E484Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.157 136 2 1.5% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125.1 136 99 72.8% 0 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.125.1 136 11 8.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125.1 136 9 6.6% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125.1 136 8 5.9% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N,R1091C]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125.1 136 4 2.9% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,G946V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.314 136 85 62.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.314 136 39 28.7% 1 +[Y145H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.314 136 8 5.9% 1 +[G1219S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.314 136 1 0.7% 5 +[L141-,G142-,V143-,G1219S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.314 136 1 0.7% 1 +[G35V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DV.7.1.1 136 97 71.3% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,N679R,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,N679K] (consensus) DV.7.1.1 136 8 5.9% 1 +[K147E,W152R,F157L,N185D,I210V,G257S,K444T,L452R,L455F,F456L,F486S,N679R,L858I]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F486P,F490S,N679K] DV.7.1.1 136 4 2.9% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,N679R,L858I,A1078S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,N679K] DV.7.1.1 136 3 2.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,N679R,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,Y505H,N679K] DV.7.1.1 136 3 2.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,S359N,K444T,L452R,L455F,F456L,F486S,N679R,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,N679K] AY.55 136 58 42.6% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.55 136 42 30.9% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.55 136 4 2.9% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.55 136 3 2.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,M1237V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.55 136 3 2.2% 1 +[T19R,E156G,F157-,R158-,A222V,T430I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DY.1.1 136 110 80.9% 0 +[H69-,V70-,K147E,V213G,G339D,L452R,F486V,A570S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DY.1.1 136 6 4.4% 2 +[L5F,H69-,V70-,K147E,E180G,V213G,G339D,L452R,F486V,A570S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.1.1 136 3 2.2% 1 +[H69-,V70-,K147E,V213G,G339D,L452R,F486V,A570S,S813T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.1.1 136 2 1.5% 1 +[H69-,V70-,K147E,V213G,G339D,L452R,F486V,A570S,T1116A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.1.1 136 2 1.5% 1 +[H69-,V70-,H146Y,K147E,V213G,G339D,L452R,F486V,A570S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CK.1.1 136 96 70.6% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,N856S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1.1 136 13 9.6% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,P812S,N856S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.1 136 5 3.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,N856S,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.1 136 5 3.7% 1 +[H69-,V70-,K182I,V213G,G339D,K444N,L452R,F486V,N856S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.1 136 2 1.5% 1 +[H69-,V70-,V213G,G339D,R346I,K444N,L452R,F486V,N856S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FY.4.1.2 135 91 67.4% 0 +[Y200C,Y451H,S494P] (consensus) FY.4.1.2 135 10 7.4% 1 +[Y200C,Y451H,S494P,F1103S] FY.4.1.2 135 5 3.7% 1 +[G184S,Y200C,Y451H,S494P] FY.4.1.2 135 3 2.2% 1 +[Y200C,Y451H,S494P]-[K417N] FY.4.1.2 135 3 2.2% 1 +[H146K,Y200C,Y451H,S494P]-[H146Q] EG.1.5 135 83 61.5% 0 +[S98F,Q613H] (consensus) EG.1.5 135 14 10.4% 1 +[S98F,T286I,Q613H] EG.1.5 135 4 3.0% 1 +[H49Y,S98F,Q613H] EG.1.5 135 4 3.0% 1 +[S98F,D215G,Q613H] EG.1.5 135 3 2.2% 1 +[S98F,Q613H]-[T19I] AY.25.1.1 135 85 63.0% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] (consensus) AY.25.1.1 135 14 10.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] AY.25.1.1 135 8 5.9% 1 +[T19R,E156G,F157-,R158-,V367L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] AY.25.1.1 135 5 3.7% 2 +[T19R,E156G,F157-,R158-,M177I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] AY.25.1.1 135 3 2.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] P.6 135 88 65.2% 0 +[Q675H,Q677H,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.6 135 9 6.7% 1 +[Q677H,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.6 135 8 5.9% 1 +[Q271R,Q675H,Q677H,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.6 135 5 3.7% 1 +[Q675H,Q677H,V1176F,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.6 135 3 2.2% 2 +[Q271R,Q675H,Q677H,V772I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CP.5 135 96 71.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.5 135 12 8.9% 1 +[H69-,V70-,V213G,T250I,G339D,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.5 135 5 3.7% 2 +[H69-,V70-,V213G,T250I,G339D,K417T,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] CP.5 135 3 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] CP.5 135 2 1.5% 1 +[H69-,V70-,V213G,G339D,P384S,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EE.4 135 57 42.2% 0 +[Q52H,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EE.4 135 40 29.6% 1 +[Q52H,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.4 135 6 4.4% 2 +[Q52H,H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V,A1070T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.4 135 4 3.0% 1 +[Q52H,H69-,V70-,K150E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.4 135 2 1.5% 1 +[Q52H,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BA.5.2.5 135 116 85.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.5 135 4 3.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.5 135 2 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.5 135 2 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.5 135 1 0.7% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] N.3 134 108 80.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.3 134 3 2.2% 1 +[D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.3 134 3 2.2% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.3 134 2 1.5% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.3 134 1 0.7% 1 +[K558N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.210 134 119 88.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.210 134 4 3.0% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.210 134 2 1.5% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.210 134 1 0.7% 3 +[V143D,Y145-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.210 134 1 0.7% 1 +[Q183H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.9.5 134 71 53.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.9.5 134 18 13.4% 2 +[E1195D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.9.5 134 8 6.0% 2 +[D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.9.5 134 7 5.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.9.5 134 4 3.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GN.3 134 71 53.0% 0 (consensus) GN.3 134 10 7.5% 1 +[F456L] GN.3 134 5 3.7% 1 +[H146K]-[H146Q] GN.3 134 5 3.7% 1 +[D1084G] GN.3 134 4 3.0% 2 +[F456L,D1084G] BF.38.2 134 118 88.1% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.38.2 134 3 2.2% 2 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,A647S,A845S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38.2 134 3 2.2% 2 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,L938F,T1009I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38.2 134 2 1.5% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,T1116N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38.2 134 1 0.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,P812S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] A.2.3 134 109 81.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2.3 134 11 8.2% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.3 134 8 6.0% 1 +[V90F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.3 134 2 1.5% 1 +[A522S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.3 134 1 0.7% 1 +[H146R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.363 134 119 88.8% 0 +[R21I,R847K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.363 134 7 5.2% 1 +[R21I,R847K,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.363 134 3 2.2% 1 +[L5F,R21I,R847K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.363 134 1 0.7% 1 +[R21I,R847K,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.363 134 1 0.7% 1 +[R21I,T109S,R847K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.23 133 63 47.4% 0 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.23 133 45 33.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.23 133 6 4.5% 2 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.23 133 5 3.8% 1 +[T20I,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.23 133 5 3.8% 2 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.530 133 99 74.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.530 133 4 3.0% 2 +[T22I,N164H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.530 133 4 3.0% 1 +[G257S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.530 133 2 1.5% 2 +[T1117I,D1184Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.530 133 2 1.5% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.381 133 92 69.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.381 133 18 13.5% 1 +[Q218E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.381 133 8 6.0% 1 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.381 133 5 3.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.381 133 2 1.5% 1 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.59 133 119 89.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.59 133 6 4.5% 1 +[D574Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.59 133 2 1.5% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.59 133 1 0.8% 1 +[T76I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.59 133 1 0.8% 1 +[C1240F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.26 133 97 72.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.26 133 7 5.3% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.26 133 4 3.0% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.26 133 2 1.5% 1 +[H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.26 133 2 1.5% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.6.4 133 101 75.9% 0 +[H69-,V70-,V213G,G339D,R346E,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.6.4 133 9 6.8% 1 +[H69-,V70-,V213G,G339D,R346E,L452R,F486V,V1040A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.4 133 3 2.3% 1 +[H69-,V70-,V213G,G339D,R346E,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.6.4 133 3 2.3% 1 +[H69-,V70-,V213G,G339D,R346E,L452R,F486V,V987F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.4 133 2 1.5% 1 +[H69-,V70-,V213G,G339D,R346E,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.5.7 132 83 62.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5.7 132 18 13.6% 1 +[T19R,E156G,F157-,R158-,D215H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.7 132 14 10.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.7 132 2 1.5% 2 +[T19R,R21I,E156G,F157-,R158-,D215H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.7 132 2 1.5% 1 +[T19R,R21S,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.3.14 132 82 62.1% 0 +[D253G,P521S]-[G252V] (consensus) XBB.2.3.14 132 7 5.3% 2 +[N185H,D253G,P521S,A845V]-[G252V] XBB.2.3.14 132 6 4.5% 1 +[H146K,D253G,P521S]-[H146Q,G252V] XBB.2.3.14 132 3 2.3% 1 +[D253G]-[G252V] XBB.2.3.14 132 3 2.3% 1 +[D253G,P521S,A845S]-[G252V] B.1.590 132 94 71.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.590 132 10 7.6% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.590 132 6 4.5% 1 +[H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.590 132 4 3.0% 1 +[I818V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.590 132 3 2.3% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HJ.1 132 85 64.4% 0 +[E324K,T573I] (consensus) HJ.1 132 13 9.8% 1 +[E324K,T573I,T883I] HJ.1 132 8 6.1% 1 +[E324K,T573I,A1016V] HJ.1 132 8 6.1% 1 +[E324K,T573I,A892V] HJ.1 132 2 1.5% 1 +[T286I,E324K,T573I] XAY.1.1.1 132 69 52.3% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.1.1.1 132 12 9.1% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F490S] XAY.1.1.1 132 5 3.8% 1 +[L5F,L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] XAY.1.1.1 132 5 3.8% 2 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A688V,A706V,T1117I,D1153Y,D1163N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] XAY.1.1.1 132 4 3.0% 2 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F490S,Q954H] FL.1.1 132 56 42.4% 0 +[A701V,A852S] (consensus) FL.1.1 132 33 25.0% 1 +[A701V] FL.1.1 132 15 11.4% 2 +[N481K,A701V] FL.1.1 132 3 2.3% 4 +[N481K,A701V,R1091S,T1117I] FL.1.1 132 3 2.3% 1 +[A701V,A852S]-[K417N] JN.14 131 67 51.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.14 131 9 6.9% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.14 131 7 5.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] JN.14 131 4 3.1% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.14 131 3 2.3% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,N658T,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.378 131 119 90.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.378 131 2 1.5% 1 +[W152R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.378 131 1 0.8% 2 +[L176F,E1144Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.378 131 1 0.8% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.378 131 1 0.8% 1 +[S151I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.376 131 112 85.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.376 131 4 3.1% 1 +[V367I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.376 131 3 2.3% 1 +[V70F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.376 131 3 2.3% 1 +[S659L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.376 131 1 0.8% 2 +[V70F,L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.24 131 50 38.2% 0 +[T33K,F306L,E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.24 131 35 26.7% 3 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.24 131 10 7.6% 4 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.24 131 10 7.6% 4 +[C1247F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.24 131 5 3.8% 2 +[E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FY.4.1.1 130 54 41.5% 0 +[Y200C,Y451H,S494P,S704L,D1139H] (consensus) FY.4.1.1 130 36 27.7% 1 +[Y200C,Y451H,S494P,S704L] FY.4.1.1 130 8 6.2% 2 +[Y200C,Y451H,S494P,T573I,S704L] FY.4.1.1 130 5 3.8% 1 +[Y200C,Y451H,S494P,S704L,D1139H]-[Y144-] FY.4.1.1 130 3 2.3% 1 +[V120I,Y200C,Y451H,S494P,S704L,D1139H] BA.2.56.1 130 87 66.9% 0 +[H69Y,V213G,G339D,L452M,Q493R,W886L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.56.1 130 30 23.1% 1 +[R21T,H69Y,V213G,G339D,L452M,Q493R,W886L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.56.1 130 5 3.8% 1 +[H69Y,V213G,G339D,L452M,Q493R,W886L,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.56.1 130 3 2.3% 1 +[H69Y,V213G,G339D,L452M,Q493R,T768I,W886L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.56.1 130 2 1.5% 1 +[H69Y,V213G,G339D,L452M,Q493R,G639V,W886L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] Q.6 129 102 79.1% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.6 129 7 5.4% 1 +[H69-,V70-,A570D,E654Q,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.6 129 3 2.3% 1 +[H69-,V70-,R214L,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.6 129 2 1.6% 1 +[H69-,V70-,A570D,T716I,D936Y,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.6 129 2 1.6% 1 +[H69-,V70-,K558N,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] GP.1 129 81 62.8% 0 +[Q52H,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) GP.1 129 6 4.7% 1 +[Q52H,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F456L,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GP.1 129 3 2.3% 1 +[Q52H,H146R,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GP.1 129 3 2.3% 1 +[Q52H,K147E,W152R,M153I,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GP.1 129 2 1.6% 1 +[L5F,Q52H,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.4 129 84 65.1% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.4 129 18 14.0% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,S704L,L822F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.4 129 13 10.1% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,A352S,K444T,L452R,F486S,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.4 129 2 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,S704L,Q836E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.4 129 2 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,L441F,K444T,L452R,F486S,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.218 128 63 49.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.218 128 21 16.4% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.218 128 7 5.5% 1 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.218 128 7 5.5% 1 +[D1163A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.218 128 5 3.9% 2 +[D574Y,A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.556 128 106 82.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.556 128 5 3.9% 1 +[P9S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.556 128 3 2.3% 1 +[N148T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.556 128 2 1.6% 1 +[A260V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.556 128 2 1.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.9 128 104 81.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.9 128 3 2.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,Y505H] BF.7.9 128 2 1.6% 1 +[H49Y,H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.9 128 2 1.6% 1 +[H69-,V70-,Y200C,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.9 128 2 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XBB.2.6.1 128 95 74.2% 0 +[D253G,F486S,P521S]-[G252V,F486P] (consensus) XBB.2.6.1 128 10 7.8% 1 +[M177I,D253G,F486S,P521S]-[G252V,F486P] XBB.2.6.1 128 2 1.6% 1 +[D253G,L452M,F486S,P521S]-[G252V,F486P] XBB.2.6.1 128 1 0.8% 3 +[L5F,F486S,P521S]-[F486P] XBB.2.6.1 128 1 0.8% 1 +[S247I,D253G,F486S,P521S]-[G252V,F486P] B.1.1.71 128 99 77.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.71 128 5 3.9% 1 +[A890T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.71 128 4 3.1% 1 +[G75V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.71 128 3 2.3% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.71 128 2 1.6% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.61 128 76 59.4% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.61 128 7 5.5% 1 +[H69-,V70-,E180G,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.61 128 5 3.9% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] BA.5.2.61 128 4 3.1% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.61 128 4 3.1% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,D936A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.63 128 112 87.5% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BA.5.2.63 128 7 5.5% 1 +[L5F,H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.63 128 2 1.6% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,P681Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,P681H] BA.5.2.63 128 1 0.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,K1086E]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.63 128 1 0.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,G1171D]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FC.1 128 57 44.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] (consensus) FC.1 128 12 9.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] FC.1 128 9 7.0% 2 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] FC.1 128 3 2.3% 1 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] FC.1 128 3 2.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] HG.1 128 75 58.6% 0 +[S98F,D253G,T478R,P521S]-[G252V,T478K] (consensus) HG.1 128 21 16.4% 2 +[S98F,D253G,T478R,P521S,P1162L,A1190S]-[G252V,T478K] HG.1 128 13 10.2% 1 +[S98F,D253G,T478R,P521S,A1190S]-[G252V,T478K] HG.1 128 5 3.9% 3 +[S98F,N148H,D253G,T478R,P521S,P1162L,A1190S]-[G252V,T478K] HG.1 128 1 0.8% 1 +[S98F,G181A,D253G,T478R,P521S]-[G252V,T478K] GA.2 128 77 60.2% 0 +[D215H] (consensus) GA.2 128 6 4.7% 1 +[D215H,T547I] GA.2 128 3 2.3% 1 +[D215H,T385I] GA.2 128 3 2.3% 1 +[H146K,D215H]-[H146Q] GA.2 128 2 1.6% 1 +[D215H,E554K] BA.2.3.8 127 111 87.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.8 127 3 2.4% 2 +[V213G,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.3.8 127 3 2.4% 1 +[V213G,G339D,Q493R,T791P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.8 127 2 1.6% 1 +[V213G,G339D,Q493R,A893V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.8 127 1 0.8% 1 +[V213G,G339D,Q493R,A845S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BZ.1 127 120 94.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BZ.1 127 3 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H,N824S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BZ.1 127 1 0.8% 5 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BZ.1 127 1 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,T478I,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BZ.1 127 1 0.8% 1 +[H69-,V70-,K150E,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CK.1.1.2 127 99 78.0% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,N856S,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1.1.2 127 6 4.7% 1 +[H69-,V70-,L176F,V213G,G339D,K444N,L452R,F486V,N856S,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.1.2 127 5 3.9% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,N856S,C1236F,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.1.2 127 4 3.1% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,N856S,G1167D,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.1.2 127 3 2.4% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,N856S,V1264L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.46 127 102 80.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BA.5.2.46 127 5 3.9% 1 +[S31F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.46 127 5 3.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T724I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.46 127 2 1.6% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T1117I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.46 127 2 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.1.163 126 73 57.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.163 126 15 11.9% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.163 126 11 8.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.163 126 4 3.2% 1 +[A67S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.163 126 4 3.2% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.5.2 126 110 87.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N481K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.5.2 126 2 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T286I,K356T,N481K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.5.2 126 1 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N481K,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.5.2 126 1 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N481K,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.5.2 126 1 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N481K,E484V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P] EG.1.8 126 101 80.2% 0 +[Q613H,S640F] (consensus) EG.1.8 126 4 3.2% 1 +[H146K,Q613H,S640F]-[H146Q] EG.1.8 126 2 1.6% 1 +[Q613H,S640F,M1237V] EG.1.8 126 1 0.8% 1 +[A348E,Q613H,S640F] EG.1.8 126 1 0.8% 2 +[Q613H,S640F,I1225V]-[Y144-] B.1.1.517 126 119 94.4% 0 +[T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.517 126 2 1.6% 1 +[T732A,Q1201K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.517 126 1 0.8% 2 +[A163V,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.517 126 1 0.8% 1 +[T732A,E1195D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.517 126 1 0.8% 1 +[P384L,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XW 126 105 83.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XW 126 5 4.0% 1 +[V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XW 126 4 3.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XW 126 2 1.6% 1 +[V213G,G339D,Q493R,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XW 126 2 1.6% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.4.3 126 87 69.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.4.3 126 11 8.7% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.3 126 5 4.0% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,I624V,P681R,S939F,P1143L,L1186I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.3 126 2 1.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.3 126 2 1.6% 3 +[+16MPLF,R21T,S46L,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.4.1.2 126 104 82.5% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.2 126 3 2.4% 1 +[V3G,H69-,V70-,V213G,T315I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.2 126 2 1.6% 2 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N679K,P681H] BA.4.1.2 126 2 1.6% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.1.2 126 2 1.6% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.41 126 109 86.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.41 126 11 8.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.41 126 1 0.8% 1 +[S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.41 126 1 0.8% 1 +[F456L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.41 126 1 0.8% 2 +[L5F,A344S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.194 126 119 94.4% 0 +[K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.194 126 3 2.4% 2 +[T307N,K1073N,S1261F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.194 126 1 0.8% 4 +[S50L,Y269C,T307N,K1073N,S1261F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.194 126 1 0.8% 1 +[A262S,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.194 126 1 0.8% 1 +[K1073N,E1195D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HZ.3 126 101 80.2% 0 +[P521T] (consensus) HZ.3 126 4 3.2% 2 +[N148T,P521T,A653V] HZ.3 126 3 2.4% 1 +[P521T,A771N] HZ.3 126 3 2.4% 1 +[R346I,P521T]-[R346T] HZ.3 126 3 2.4% 1 +[F157S,P521T] XBB.1.5.89 126 60 47.6% 0 +[T478R,E554A]-[T478K] (consensus) XBB.1.5.89 126 7 5.6% 2 +[T478R,E554A,V687I]-[T19I,T478K] XBB.1.5.89 126 6 4.8% 1 +[F157S,T478R,E554A]-[T478K] XBB.1.5.89 126 5 4.0% 1 +[N148T,T478R,E554A]-[T478K] XBB.1.5.89 126 4 3.2% 1 +[T478R,E554A,V687I]-[T478K] JN.5 126 49 38.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.5 126 19 15.1% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.5 126 10 7.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] JN.5 126 8 6.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.5 126 3 2.4% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.412 125 98 78.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.412 125 5 4.0% 1 +[S255Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.412 125 3 2.4% 1 +[I468T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.412 125 2 1.6% 3 +[G257D,E484K,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.412 125 2 1.6% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.237 125 118 94.4% 0 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.237 125 4 3.2% 1 +[L5F,R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.237 125 3 2.4% 1 +[R21I,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.124 125 115 92.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.124 125 3 2.4% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.124 125 3 2.4% 1 +[G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.124 125 2 1.6% 1 +[I1221T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.124 125 1 0.8% 1 +[S494L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FG.2 125 96 76.8% 0 +[D178N] (consensus) FG.2 125 8 6.4% 1 +[D178N,T478R]-[T478K] FG.2 125 7 5.6% 1 +[D178N,V483F] FG.2 125 3 2.4% 1 +[D178N,T385I] FG.2 125 2 1.6% 1 +[H146K,D178N]-[H146Q] EK.2.1 125 115 92.0% 0 +[T259I,T478R]-[T478K] (consensus) EK.2.1 125 2 1.6% 1 +[T259I,T478R,A684V]-[T478K] EK.2.1 125 1 0.8% 2 +[G257S,T259V,T478R]-[T478K] EK.2.1 125 1 0.8% 1 +[E180V,T259I,T478R]-[T478K] EK.2.1 125 1 0.8% 1 +[T259I,T478R,N658I]-[T478K] AY.49 124 73 58.9% 0 +[T19R,E156G,F157-,R158-,L452R,Q493E,P681R,K854N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.49 124 25 20.2% 1 +[T19R,E156G,F157-,R158-,L452R,Q493E,P681R,K854N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.49 124 11 8.9% 1 +[T19R,E156G,F157-,R158-,L452R,Q493E,A522S,P681R,K854N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.49 124 5 4.0% 2 +[T19R,E156G,F157-,R158-,L452R,Q493E,A522S,P681R,K854N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.49 124 2 1.6% 2 +[T19R,E156G,F157-,R158-,L452R,Q493E,P681R,K854N,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.323 124 106 85.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.323 124 6 4.8% 1 +[A67V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.323 124 5 4.0% 1 +[E1188V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.323 124 1 0.8% 1 +[T547K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.323 124 1 0.8% 1 +[S1242I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.3 124 44 35.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,T791I,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.3 124 26 21.0% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,T791I,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.3 124 14 11.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,T791I,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.3 124 5 4.0% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,T791I,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.1.3 124 3 2.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,T791I,N856K,S940F,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.1.164 124 108 87.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.164 124 4 3.2% 1 +[A243V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.164 124 3 2.4% 2 +[T95I,G1085A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.164 124 2 1.6% 1 +[G1085A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.164 124 1 0.8% 1 +[V729A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91.1 123 63 51.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.91.1 123 39 31.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91.1 123 6 4.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91.1 123 2 1.6% 1 +[T19R,E156G,F157-,R158-,T323I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91.1 123 2 1.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1224F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.113 123 102 82.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.113 123 7 5.7% 1 +[L1244I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.113 123 4 3.3% 1 +[D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.113 123 3 2.4% 2 +[A522V,L1244I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.113 123 2 1.6% 1 +[P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.86.3 123 84 68.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) BA.2.86.3 123 4 3.3% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.3 123 4 3.3% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.3 123 3 2.4% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.3 123 3 2.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BQ.1.33 123 70 56.9% 0 +[H69-,V70-,K147I,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.33 123 20 16.3% 1 +[L5F,H69-,V70-,K147I,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.33 123 7 5.7% 1 +[H69-,V70-,K147I,F157L,V213G,G339D,K444T,L452R,F486V,S1170F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.33 123 6 4.9% 1 +[H69-,V70-,K147I,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.33 123 3 2.4% 1 +[V62L,H69-,V70-,K147I,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] KQ.1 123 66 53.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KQ.1 123 25 20.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] KQ.1 123 4 3.3% 11 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] KQ.1 123 4 3.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A852V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KQ.1 123 3 2.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] XBB.1.13 123 54 43.9% 0 +[L5F,F486S,F490P]-[F486P,F490S] (consensus) XBB.1.13 123 27 22.0% 1 +[F486S,F490P]-[F486P,F490S] XBB.1.13 123 6 4.9% 3 +[F486S,F490P]-[R408S,S477N,F486P,F490S] XBB.1.13 123 4 3.3% 2 +[F486S,F490P,S689R]-[F486P,F490S] XBB.1.13 123 2 1.6% 2 +[T51I,F486S,F490P]-[F486P,F490S] B.1.463 123 98 79.7% 0 +[F59Y,P384L,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.463 123 16 13.0% 1 +[P384L,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.463 123 3 2.4% 1 +[F59Y,V70F,P384L,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.463 123 1 0.8% 1 +[F59Y,R346K,P384L,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.463 123 1 0.8% 2 +[P384L,P812S,C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.252 123 115 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.252 123 5 4.1% 1 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.252 123 1 0.8% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.252 123 1 0.8% 1 +[V362F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.252 123 1 0.8% 1 +[T299A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.3 122 78 63.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D936G,D950N,P1263Q]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.112.3 122 25 20.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D936G,D950N,P1263Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.3 122 4 3.3% 2 +[T19R,T95I,E156G,F157-,R158-,A372V,L452R,P681R,D936G,D950N,P1263Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.3 122 3 2.5% 1 +[T19R,T95I,E156G,F157-,R158-,A372V,L452R,P681R,D936G,D950N,P1263Q]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.3 122 2 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,P681R,D936G,D950N,P1263Q]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.59 122 75 61.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T732I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.59 122 12 9.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H,T732I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.59 122 5 4.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A701V,T732I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.59 122 5 4.1% 4 +[H69-,V70-,W152L,V213G,G339D,K444T,L452R,F486V,T547K,T732I,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.59 122 5 4.1% 3 +[H69-,V70-,W152L,V213G,G339D,K444T,L452R,F486V,T732I,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] HS.1.1 122 80 65.6% 0 +[F456L,T478R]-[T478K] (consensus) HS.1.1 122 21 17.2% 1 +[F456L,T478R,D1139N]-[T478K] HS.1.1 122 6 4.9% 1 +[F456L,T478R,T1136I]-[T478K] HS.1.1 122 2 1.6% 1 +[F456L,T478R]-[K417N,T478K] HS.1.1 122 2 1.6% 1 +[H146K,F456L,T478R]-[H146Q,T478K] FL.5.1 122 68 55.7% 0 +[M177T] (consensus) FL.5.1 122 29 23.8% 1 +[M177T,V1094F] FL.5.1 122 3 2.5% 2 +[M177T,V1094F]-[K417N] FL.5.1 122 3 2.5% 1 +[M177T,T478R]-[T478K] FL.5.1 122 2 1.6% 1 +[P139S,M177T] EU.1.1.3 121 79 65.3% 0 +[F157L,I410V,P521S] (consensus) EU.1.1.3 121 14 11.6% 2 +[F157L,I410V,P521S,Q957H,V1264L] EU.1.1.3 121 8 6.6% 1 +[F157L,I410V,P521S,V1264L] EU.1.1.3 121 4 3.3% 1 +[F157L,I410V,P521S]-[K417N] EU.1.1.3 121 2 1.7% 6 +[F456L,S704L,N1178D] EK.3 121 85 70.2% 0 +[P251S] (consensus) EK.3 121 10 8.3% 1 +[P251S,S514F] EK.3 121 8 6.6% 1 +[D178H,P251S] EK.3 121 3 2.5% 1 +[T63N,P251S] EK.3 121 3 2.5% 2 +[P251S,S494P,E554K] B.1.160.18 121 106 87.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.18 121 4 3.3% 1 +[V785L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.18 121 3 2.5% 1 +[V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.18 121 2 1.7% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.18 121 2 1.7% 1 +[D745G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.6 121 61 50.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.6 121 43 35.5% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.6 121 3 2.5% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.6 121 2 1.7% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.6 121 1 0.8% 2 +[P26L,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.11 121 57 47.1% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,P681R,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.11 121 25 20.7% 1 +[S12F,L18F,T20N,P26S,D138Y,R190S,K417T,E484K,P681R,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.11 121 8 6.6% 2 +[S12F,L18F,T20N,P26S,R190S,K417T,E484K,P681R,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.11 121 6 5.0% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,P681R,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.11 121 3 2.5% 2 +[L18F,T20N,P26S,D138Y,H146-,R190S,K417T,E484K,P681R,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.1.11 121 111 91.7% 0 +[V3G,H69-,V70-,K147E,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.11 121 5 4.1% 1 +[V3G,H69-,V70-,K147E,W152R,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.11 121 2 1.7% 1 +[V3G,H69-,V70-,K147E,V213G,G339D,V445A,L452R,F486V,P1079S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.11 121 2 1.7% 1 +[V3G,H69-,V70-,K147E,V213G,G339D,V445A,L452R,F486V,R1185S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.11 121 1 0.8% 1 +[V3G,H69-,V70-,K147E,V213G,G339D,V445A,L452R,F486V,M740T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] FL.1.4 121 80 66.1% 0 +[T478R,A701V,Q1208H]-[T478K] (consensus) FL.1.4 121 5 4.1% 1 +[S71F,T478R,A701V,Q1208H]-[T478K] FL.1.4 121 3 2.5% 2 +[H146K,T478R,A701V,Q1208H]-[T19I,H146Q,T478K] FL.1.4 121 3 2.5% 1 +[L5F,T478R,A701V,Q1208H]-[T478K] FL.1.4 121 2 1.7% 1 +[T478R,A647S,A701V,Q1208H]-[T478K] BQ.1.15.1 121 106 87.6% 0 +[H69-,V70-,V213G,Y248S,+248DAD,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.15.1 121 5 4.1% 1 +[H69-,V70-,V213G,Y248S,+248DAD,G339D,K444T,L452R,F486V,V1060I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.15.1 121 2 1.7% 3 +[H69-,V70-,V213G,Y248S,+248DAD,G339D,K444T,L452R,F486V,Q836L,A892V,L981I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.15.1 121 1 0.8% 1 +[P9L,H69-,V70-,V213G,Y248S,+248DAD,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.15.1 121 1 0.8% 1 +[H69-,V70-,V213G,Y248S,+248DAD,G339D,K444T,L452R,F486V,T1120I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CJ.1 120 68 56.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) CJ.1 120 16 13.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L1224V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1 120 6 5.0% 1 +[K147E,W152R,F157L,F186L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1 120 3 2.5% 2 +[K147E,W152R,F157L,V213G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1 120 2 1.7% 2 +[K147E,W152R,F157L,F186L,I210V,V213G,G257S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] B.1.258.19 120 112 93.3% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.19 120 2 1.7% 1 +[H69-,V70-,F86Y,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.19 120 1 0.8% 1 +[H69-,V70-,N439K,I468V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.19 120 1 0.8% 1 +[H69-,V70-,V193L,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.19 120 1 0.8% 1 +[H69-,V70-,G181V,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.43.1 120 71 59.2% 0 (consensus) XBB.1.43.1 120 10 8.3% 1 +[H146K]-[H146Q] XBB.1.43.1 120 5 4.2% 1 +[T76I] XBB.1.43.1 120 4 3.3% 3 +[H146K,N1074S]-[Y144-,H146Q] XBB.1.43.1 120 4 3.3% 1 +[T259I] DV.7.1.3 120 84 70.0% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,A262S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.7.1.3 120 5 4.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,A262S,K444T,L452R,L455F,F456L,N481K,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1.3 120 4 3.3% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,A262S,K444T,L452R,L455F,F456L,F486S,E773Q,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1.3 120 3 2.5% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,L216F,G257S,A262S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1.3 120 3 2.5% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,A262S,K444T,L452R,L455F,F456L,F486S,D614S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,D614G] B.1.313 119 105 88.2% 0 +[D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.313 119 3 2.5% 1 +[D253G,T1076I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.313 119 3 2.5% 1 +[D253G]-[L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.313 119 2 1.7% 1 +[D253G,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.313 119 2 1.7% 1 +[R21I,D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.67 119 112 94.1% 0 +[L18F,D215H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.67 119 1 0.8% 1 +[L18F,N148T,D215H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.67 119 1 0.8% 1 +[L18F,D215H,A222V,M1233T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.67 119 1 0.8% 1 +[L18F,D215H,A222V,G1246S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.67 119 1 0.8% 1 +[L18F,L141S,D215H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FY.4.1 119 79 66.4% 0 +[Y200C,Y451H,S494P] (consensus) FY.4.1 119 8 6.7% 1 +[Y200C,Y451H,S494P]-[K417N] FY.4.1 119 4 3.4% 1 +[Y200C,Y451H,S494P,T1117I] FY.4.1 119 3 2.5% 1 +[Y200C,Y451H,S494P,T572I] FY.4.1 119 2 1.7% 1 +[H146K,Y200C,Y451H,S494P]-[H146Q] BA.5.2.39 119 83 69.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.39 119 11 9.2% 1 +[H69-,V70-,V213G,S256T,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.39 119 6 5.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.39 119 5 4.2% 1 +[H69-,V70-,L118I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.39 119 3 2.5% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,S673G,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.17 119 47 39.5% 0 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.17 119 26 21.8% 1 +[H69-,V70-,T208M,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.17 119 18 15.1% 2 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V,I794T]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.17 119 8 6.7% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.17 119 6 5.0% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V,I794T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.160.11 118 108 91.5% 0 +[V6F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.11 118 6 5.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.11 118 2 1.7% 1 +[V6F,H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.11 118 1 0.8% 1 +[V6F,F135L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.11 118 1 0.8% 1 +[F4L,V6F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.28 118 111 94.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.28 118 3 2.5% 1 +[I203L,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.28 118 1 0.8% 2 +[A222V,R765L,S1097L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.28 118 1 0.8% 1 +[S12F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.28 118 1 0.8% 1 +[A222V,T747A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.26 118 63 53.4% 0 (consensus) FL.26 118 10 8.5% 1 +[Q836L] FL.26 118 7 5.9% 1 +[H146K]-[H146Q] FL.26 118 4 3.4% 2 +[H146K]-[Y144-,H146Q] FL.26 118 4 3.4% 1 -[Y144-] GM.3 118 96 81.4% 0 +[D253G,P521S]-[G252V] (consensus) GM.3 118 3 2.5% 1 +[D253G,P521S]-[H146Q,G252V] GM.3 118 3 2.5% 1 +[G72E,D253G,P521S]-[G252V] GM.3 118 2 1.7% 2 +[D253G,P521S,A688S,T998A]-[G252V] GM.3 118 2 1.7% 1 +[D253G,R273T,P521S]-[G252V] B.1.177.84 118 61 51.7% 0 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.84 118 48 40.7% 1 +[W152R,A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.84 118 3 2.5% 2 +[W152R,A222V,A262S,P272L,F329L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.84 118 2 1.7% 2 +[W152R,A222V,A262S,P272L,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.84 118 2 1.7% 1 +[A222V,A262S,P272L,T573I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.349 118 40 33.9% 0 +[V615I,D839Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.349 118 38 32.2% 1 +[D839Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.349 118 11 9.3% 1 +[V615I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.349 118 5 4.2% 2 +[R237K,D839Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.349 118 3 2.5% 2 +[V615I,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.4.4 118 77 65.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.4.4 118 19 16.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.4 118 4 3.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,I726T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.4 118 4 3.4% 1 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4.4 118 2 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,K1205N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBG 118 83 70.3% 0 +[V213G,Y248N,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XBG 118 10 8.5% 1 +[V213G,Y248N,G339D,L452R,F486V,P809S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBG 118 5 4.2% 1 +[V213G,Y248N,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XBG 118 3 2.5% 1 +[V213G,Y248N,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBG 118 2 1.7% 1 +[V213G,Y248N,G339D,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.75.6 118 31 26.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.2.75.6 118 26 22.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BA.2.75.6 118 8 6.8% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.6 118 7 5.9% 9 +[D111N,K147E,S151N,W152R,F157L,I210V,V213G,G257S,V289I,T549I,D574N,A701V,L841F,V1230M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.6 118 3 2.5% 3 +[K147E,W152R,F157L,Q183H,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.273 117 81 69.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.273 117 10 8.5% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.273 117 8 6.8% 1 +[S689I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.273 117 2 1.7% 1 +[N1074H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.273 117 2 1.7% 2 +[G142V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] BQ.1.7 117 85 72.6% 0 +[L54F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.7 117 9 7.7% 1 +[L54F,H69-,V70-,V213G,T284I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.7 117 8 6.8% 3 +[L54F,H69F,V70-,S71-,V213G,T284I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.7 117 2 1.7% 2 +[L54F,H69-,V70-,V213G,D228H,T284I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.7 117 2 1.7% 1 +[L54F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.160.22 117 111 94.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.22 117 3 2.6% 1 +[A67V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.22 117 1 0.9% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.22 117 1 0.9% 2 +[P272L,S982A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.22 117 1 0.9% 2 +[T385I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.413 117 102 87.2% 0 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.413 117 3 2.6% 1 +[D138Y,D253Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.413 117 2 1.7% 1 +[D138Y,G504D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.413 117 1 0.9% 1 +[D138Y,A419S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.413 117 1 0.9% 3 +[R78K,D138Y,A163T,G181A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.548 116 45 38.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.548 116 10 8.6% 1 +[A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.548 116 7 6.0% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.548 116 7 6.0% 2 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.548 116 4 3.4% 1 +[V1133F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.391 116 94 81.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.391 116 5 4.3% 1 +[G838S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.391 116 4 3.4% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.391 116 2 1.7% 2 +[A67V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.391 116 2 1.7% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.244 116 75 64.7% 0 +[G75R,G257S,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.244 116 29 25.0% 3 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.244 116 2 1.7% 1 +[G75R,G257S,A647S,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.244 116 2 1.7% 4 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.244 116 1 0.9% 4 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.225 116 109 94.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.225 116 1 0.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.225 116 1 0.9% 2 +[Q677H,A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.225 116 1 0.9% 1 +[K202T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.225 116 1 0.9% 1 +[H69D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.4 116 51 44.0% 0 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.4 116 31 26.7% 2 +[A222V,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] C.4 116 8 6.9% 1 +[N185D,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.4 116 5 4.3% 3 +[A222V,A684V,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] C.4 116 3 2.6% 1 +[A1078S,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.17 116 94 81.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.17 116 5 4.3% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.17 116 4 3.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,V483F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.17 116 3 2.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,K933E,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.17 116 2 1.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.406 115 107 93.0% 0 +[G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.406 115 2 1.7% 1 +[T73N,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.406 115 1 0.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.406 115 1 0.9% 2 +[L5F,I1169F,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.406 115 1 0.9% 1 +[D1163Y,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.32 115 86 74.8% 0 +[T588S,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.32 115 9 7.8% 3 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.32 115 7 6.1% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.32 115 5 4.3% 1 +[T588S,K1073N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.32 115 3 2.6% 1 +[T95I,T588S,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.14.3 115 94 81.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A626V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14.3 115 2 1.7% 1 +[H69-,V70-,V213G,P330S,G339D,L452R,F486V,A626V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.3 115 2 1.7% 1 +[H69-,V70-,I101V,V213G,G339D,L452R,F486V,A626V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.3 115 2 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A626V,H1159R,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.3 115 2 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A626V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,N460K,F486P,F490S] XQ 115 108 93.9% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XQ 115 3 2.6% 1 +[V213G,G339D,Q493R,P1263S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XQ 115 2 1.7% 2 +[I68T,V213G,G339D,Q493R,P807S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XQ 115 1 0.9% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XQ 115 1 0.9% 1 +[V213G,G339D,Q493R,T618A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.34 115 64 55.7% 0 +[D1118Y] (consensus) FL.34 115 13 11.3% 1 +[N282I,D1118Y] FL.34 115 7 6.1% 1 +[S689I,D1118Y] FL.34 115 3 2.6% 2 +[N282I,E583Q,D1118Y] FL.34 115 2 1.7% 4 +[H146K,N282I,E583Q,D1118Y,Q1208H]-[H146Q] XBT 115 97 84.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XBT 115 3 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,G446S,N460K,F486P,F490S] XBT 115 2 1.7% 1 +[K147E,W152R,F157L,V213G,G257S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,F486P,F490S] XBT 115 1 0.9% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486V,T1117I,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,F486P,F490S] XBT 115 1 0.9% 5 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.28.1 114 85 74.6% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.28.1 114 4 3.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A684T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.28.1 114 4 3.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.28.1 114 3 2.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.28.1 114 2 1.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] B.1.1.161 114 67 58.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.161 114 8 7.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.161 114 6 5.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.161 114 2 1.8% 4 +[G566-,V615E,N616I,C617G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.161 114 2 1.8% 4 +[S31F,A892V,T1066I,T1100I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.12 114 77 67.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.12 114 4 3.5% 1 +[K147E,W152R,F157L,P209S,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.12 114 4 3.5% 1 +[K147E,W152R,F157L,A163T,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.12 114 3 2.6% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,L858I,P1162R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] CH.1.1.12 114 2 1.8% 1 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.478 114 87 76.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.478 114 5 4.4% 1 +[I1232V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.478 114 3 2.6% 1 +[S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.478 114 2 1.8% 1 +[T547I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.478 114 2 1.8% 1 +[I1169F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EF.1.3 114 73 64.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EF.1.3 114 12 10.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,D1163N]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1.3 114 5 4.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EF.1.3 114 2 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EF.1.3 114 2 1.8% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BF.7.14.7 114 109 95.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,S1021F,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14.7 114 2 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S1021F,D1199N,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.7 114 2 1.8% 1 +[H69-,V70-,V213G,S221L,G339D,L452R,F486V,S1021F,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.7 114 1 0.9% 1 +[T19V,H69-,V70-,V213G,G339D,L452R,F486V,S1021F,C1243F]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.532 114 101 88.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.532 114 8 7.0% 1 +[V127F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.532 114 2 1.8% 1 +[E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.532 114 2 1.8% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.532 114 1 0.9% 4 +[L141-,G142-,V143-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.137 114 109 95.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.137 114 1 0.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.137 114 1 0.9% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.137 114 1 0.9% 1 +[E154Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.137 114 1 0.9% 1 +[G75R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.21.1 114 54 47.4% 0 +[E554A,D1084N] (consensus) FL.21.1 114 24 21.1% 1 +[D1084N] FL.21.1 114 5 4.4% 1 +[T323I,E554A,D1084N] FL.21.1 114 3 2.6% 1 +[H146K,E554A,D1084N]-[H146Q] FL.21.1 114 2 1.8% 1 +[V70L,E554A,D1084N] XH 113 66 58.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XH 113 16 14.2% 1 +[V213G,G339D,Q493R,D1260Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XH 113 15 13.3% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XH 113 6 5.3% 5 +[V213G,G339D,Q493R,D1260Y]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XH 113 5 4.4% 1 +[V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.59 113 96 85.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.59 113 5 4.4% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.59 113 2 1.8% 1 +[V642F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.59 113 2 1.8% 1 +[F855L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.59 113 2 1.8% 1 +[T549I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DN.3 113 56 49.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.3 113 32 28.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A846V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.3 113 4 3.5% 2 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] DN.3 113 4 3.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,C1241F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.3 113 3 2.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] BA.2.60 113 60 53.1% 0 +[V213G,G339D,Q493R,V1129I,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.60 113 44 38.9% 1 +[V213G,G339D,Q493R,V1129I,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.60 113 6 5.3% 1 +[V213G,G339D,Q493R,V1129I,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.60 113 1 0.9% 1 +[V213G,G339D,Q493R,N556D,V1129I,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.60 113 1 0.9% 2 +[V213G,G339D,Q493R,V1129I,P1162S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] FL.35 113 84 74.3% 0 (consensus) FL.35 113 3 2.7% 1 +[H146K]-[H146Q] FL.35 113 3 2.7% 3 +[T323I,T883I,V1264L] FL.35 113 3 2.7% 1 +[L1203F] FL.35 113 2 1.8% 2 +[T478R,E990D]-[T478K] FG.3 113 83 73.5% 0 +[I934V] (consensus) FG.3 113 7 6.2% 1 +[G257D,I934V] FG.3 113 5 4.4% 2 +[I934V]-[G142D,K417N] FG.3 113 4 3.5% 1 +[H245Y,I934V] FG.3 113 2 1.8% 1 +[P812S,I934V] BG.3 113 64 56.6% 0 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] (consensus) BG.3 113 31 27.4% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.3 113 5 4.4% 2 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.3 113 3 2.7% 1 +[V213G,G339D,L452Q,Q493R,S704L,I818V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BG.3 113 2 1.8% 1 +[V213G,V308L,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.30 112 92 82.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.30 112 4 3.6% 2 +[H69-,V70-,V213G,T299I,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.30 112 2 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1246C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.30 112 2 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.30 112 1 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A706V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] FL.33 112 70 62.5% 0 (consensus) FL.33 112 5 4.5% 1 +[V483F] FL.33 112 3 2.7% 2 -[R408S,S477N] FL.33 112 2 1.8% 1 -[R408S] FL.33 112 2 1.8% 1 -[R346T] D.3 112 111 99.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) D.3 112 1 0.9% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JD.1.1.2 112 95 84.8% 0 +[L455F,F456L,A475V,E583D] (consensus) JD.1.1.2 112 9 8.0% 2 +[H146K,L455F,F456L,A475V,E484K,E583D]-[H146Q,E484A] JD.1.1.2 112 2 1.8% 1 +[M177I,L455F,F456L,A475V,E583D] JD.1.1.2 112 1 0.9% 2 +[T259I,L455F,F456L,A475V,E583D,V642G] JD.1.1.2 112 1 0.9% 2 +[L5F,L455F,F456L,A475V,E583D,V642G] BA.1.16.1 112 103 92.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.16.1 112 1 0.9% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16.1 112 1 0.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,R214H,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16.1 112 1 0.9% 1 +[S12F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16.1 112 1 0.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212-,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AB.1 112 103 92.0% 0 +[P251L,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AB.1 112 7 6.2% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AB.1 112 1 0.9% 1 +[P251L,E471K,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AB.1 112 1 0.9% 3 +[P251L,S477R,S673T,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] FL.4.8 112 74 66.1% 0 +[T478R]-[T478K] (consensus) FL.4.8 112 15 13.4% 1 +[T478R,N556K]-[T478K] FL.4.8 112 2 1.8% 1 +[H146K,T478R]-[H146Q,T478K] FL.4.8 112 1 0.9% 1 +[V36I,T478R]-[T478K] FL.4.8 112 1 0.9% 2 +[T22I,T478R,N606K]-[T478K] JN.1.1.6 111 23 20.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.1.6 111 23 20.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.1.6 111 21 18.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] JN.1.1.6 111 6 5.4% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.1.6 111 5 4.5% 6 +[R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.1.133 111 65 58.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.133 111 11 9.9% 1 +[W258R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.133 111 5 4.5% 1 +[V911I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.133 111 5 4.5% 1 +[G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.133 111 3 2.7% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CP.1.1 111 93 83.8% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.1.1 111 3 2.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.1.1 111 2 1.8% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,H1101Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.1.1 111 2 1.8% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,T676I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.1.1 111 1 0.9% 1 +[H49Y,H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.468 111 54 48.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.468 111 23 20.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.468 111 3 2.7% 2 +[A264S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.468 111 2 1.8% 1 +[P631S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.468 111 2 1.8% 2 +[A222V,T678I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.17 111 86 77.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V,G1167S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.17 111 4 3.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V,G1167S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BF.7.17 111 4 3.6% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V,G1167S,C1243S,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.17 111 3 2.7% 1 +[H69-,V70-,V213G,S254F,G339D,L452R,F486V,A688V,G1167S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.17 111 2 1.8% 1 +[H69-,V70-,V213G,D215G,G339D,L452R,F486V,A688V,G1167S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CH.1.1.30 111 43 38.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.30 111 32 28.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.30 111 6 5.4% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] CH.1.1.30 111 4 3.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,S371F,V445P,F486P,F490S] CH.1.1.30 111 3 2.7% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] DV.3.1 111 85 76.6% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.3.1 111 5 4.5% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.3.1 111 2 1.8% 1 +[K147E,W152R,F157L,G181R,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.3.1 111 2 1.8% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,A264S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.3.1 111 1 0.9% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,H1058Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.382 110 55 50.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.382 110 43 39.1% 1 +[Q52H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.382 110 3 2.7% 2 +[Q52H,Y904H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.382 110 2 1.8% 2 +[Q52H,H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.382 110 2 1.8% 2 +[Q52H,G1085R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.518 110 70 63.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.518 110 12 10.9% 1 +[I818V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.518 110 6 5.5% 1 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.518 110 4 3.6% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.518 110 3 2.7% 2 +[D427N,I818V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.30.1 110 104 94.5% 0 +[S255F,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.30.1 110 2 1.8% 1 +[L5F,S255F,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.30.1 110 1 0.9% 1 +[S255F,P863S,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.30.1 110 1 0.9% 1 +[S255F,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.30.1 110 1 0.9% 1 +[S255F,I818V,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.219 110 92 83.6% 0 +[E281V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.219 110 7 6.4% 1 +[E281V,E1111Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.219 110 2 1.8% 1 +[E281V,Y660H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.219 110 2 1.8% 1 +[E281V,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.219 110 2 1.8% 2 +[E281V,E1111Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] CR.1.3 110 88 80.0% 0 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CR.1.3 110 5 4.5% 1 +[H69-,V70-,Y170H,V213G,G339D,K444R,L452R,F486V]-[V83A,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1.3 110 3 2.7% 1 +[H69-,V70-,E132A,V213G,G339D,K444R,L452R,F486V]-[V83A,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1.3 110 2 1.8% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] CR.1.3 110 2 1.8% 1 +[H69-,V70-,V213G,H245Y,G339D,K444R,L452R,F486V]-[V83A,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EJ.1 110 79 71.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H,I1225V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) EJ.1 110 7 6.4% 1 +[K147E,W152R,F157L,G184S,I210V,V213G,G257S,K356T,D1139H,I1225V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.1 110 5 4.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F1109L,D1139H,I1225V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.1 110 2 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S640F,D1139H,I1225V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.1 110 2 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H,I1225V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.2.75.10 110 30 27.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75.10 110 11 10.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,A684V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.10 110 7 6.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.10 110 5 4.5% 4 +[K147E,W152R,F157L,I210V,V213G,G257S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.10 110 4 3.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,F486P,F490S] FZ.1.1 109 63 57.8% 0 +[E583D,L858I] (consensus) FZ.1.1 109 22 20.2% 1 +[E583D,L858I,I1115V] FZ.1.1 109 11 10.1% 1 +[T430I,E583D,L858I] FZ.1.1 109 1 0.9% 1 +[S162I,E583D,L858I] FZ.1.1 109 1 0.9% 1 +[R21T,E583D,L858I] FL.9 109 75 68.8% 0 (consensus) FL.9 109 13 11.9% 4 +[N185K,+185MAG] FL.9 109 3 2.8% 1 +[E516Q] FL.9 109 2 1.8% 1 +[H146K]-[H146Q] FL.9 109 2 1.8% 1 +[D796H]-[D796Y] B.1.258.2 109 103 94.5% 0 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.2 109 3 2.8% 1 +[N439K,C1240F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.2 109 1 0.9% 1 +[E156V,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.2 109 1 0.9% 1 +[N439K,L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.2 109 1 0.9% 1 +[I68T,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.166 109 84 77.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.166 109 8 7.3% 1 +[A411S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.166 109 6 5.5% 1 +[D215H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.166 109 3 2.8% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.166 109 2 1.8% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.4.4 109 69 63.3% 0 (consensus) EG.4.4 109 9 8.3% 2 +[A263T,D1118H] EG.4.4 109 6 5.5% 1 -[K417N] EG.4.4 109 3 2.8% 1 +[Q52H] EG.4.4 109 2 1.8% 3 +[V445L]-[G142D,R408S,V445P] B.1.424 109 78 71.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.424 109 23 21.1% 1 +[V785I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.424 109 2 1.8% 1 +[T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.424 109 1 0.9% 1 +[T1116I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.424 109 1 0.9% 1 +[A262T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.36 109 99 90.8% 0 +[H69-,V70-,V213G,G261V,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.36 109 3 2.8% 1 +[H69-,V70-,V213G,G261V,G339D,L452R,F486V,P1079S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.36 109 2 1.8% 1 +[H69-,V70-,V213G,G261V,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.36 109 1 0.9% 1 +[H69-,V70-,A163T,V213G,G261V,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.36 109 1 0.9% 2 +[H69-,V70-,V213G,R214H,G261V,G339D,L452R,F486V,A1078S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.40 109 48 44.0% 0 +[T478I]-[T478K] (consensus) XBB.1.5.40 109 7 6.4% 1 +[D178N,T478I]-[T478K] XBB.1.5.40 109 6 5.5% 1 +[T478I,P521S]-[T478K] XBB.1.5.40 109 4 3.7% 1 +[H146K,T478I]-[H146Q,T478K] XBB.1.5.40 109 3 2.8% 1 +[T51I,T478I]-[T478K] JN.1.36 108 32 29.6% 0 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.36 108 31 28.7% 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.36 108 10 9.3% 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.36 108 4 3.7% 1 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,L293F,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.36 108 3 2.8% 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BQ.1.1.25 108 94 87.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P] (consensus) BQ.1.1.25 108 6 5.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P] BQ.1.1.25 108 1 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,D1259Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P] BQ.1.1.25 108 1 0.9% 1 +[H69-,V70-,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P] BQ.1.1.25 108 1 0.9% 1 +[H69-,V70-,V213G,T240I,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P] B.1.160.25 108 97 89.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.25 108 3 2.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.25 108 2 1.9% 1 +[G446V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.25 108 1 0.9% 1 +[A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.25 108 1 0.9% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XL 108 103 95.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XL 108 5 4.6% 1 +[V213G,G339D,Q493R,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] HA.2 108 82 75.9% 0 +[P521S] (consensus) HA.2 108 6 5.6% 1 +[P521S]-[R346T] HA.2 108 4 3.7% 1 +[A348P,P521S] HA.2 108 2 1.9% 1 +[H146K,P521S]-[H146Q] HA.2 108 1 0.9% 2 +[P521S]-[R346T,K417N] B.1.1.200 108 99 91.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.200 108 2 1.9% 1 +[I402V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.200 108 2 1.9% 1 +[I1210M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.200 108 2 1.9% 1 +[S151I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.200 108 1 0.9% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XCM 108 74 68.5% 0 +[F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) XCM 108 5 4.6% 1 +[F157L,N185D,I210V,V213G,G257S,K444M,L452R,L455F,F456L,F486S,L858I]-[Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XCM 108 3 2.8% 1 +[F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,H655F,L858I]-[Q183E,V213E,G252V,L368I,V445P,F486P,F490S,H655Y] XCM 108 3 2.8% 1 +[F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I,P1162L]-[Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XCM 108 2 1.9% 1 +[F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I,G1167A]-[Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.127.3 108 70 64.8% 0 +[T19R,T95I,E156G,F157-,R158-,G446R,L452R,Q613H,P681R,D950N,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.127.3 108 24 22.2% 2 +[T19R,T95I,S98F,E156G,F157-,R158-,G446R,L452R,P681R,D950N,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127.3 108 11 10.2% 1 +[T19R,T95I,E156G,F157-,R158-,G446R,L452R,P681R,D950N,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127.3 108 1 0.9% 3 +[T19R,T95I,S98F,E156G,F157-,R158-,G446R,L452R,P681R,D936H,D950N,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127.3 108 1 0.9% 1 +[T19R,T95I,E156G,F157-,R158-,G446R,L452R,Q613H,P681R,D950N,L1063F,C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.26 107 39 36.4% 0 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.26 107 24 22.4% 1 +[L54F,D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.26 107 20 18.7% 1 +[S12F,L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.26 107 17 15.9% 2 +[L54F,D80Y,F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.26 107 3 2.8% 2 +[S12F,L54F,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EH.1 107 75 70.1% 0 +[H69-,V70-,V213G,+246N,Y248-,P251L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EH.1 107 4 3.7% 1 +[H69-,V70-,V213G,+246N,Y248-,P251L,G339D,K444T,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EH.1 107 3 2.8% 1 +[H69-,V70-,V213G,+246N,Y248-,P251L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] EH.1 107 3 2.8% 1 +[H69-,V70-,V213G,+246N,Y248-,P251L,G339D,K444T,L452R,F486V,N1187I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EH.1 107 3 2.8% 1 +[H69-,V70-,V213G,+246N,Y248-,P251L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] XBB.1.44.1 107 84 78.5% 0 +[T747I] (consensus) XBB.1.44.1 107 8 7.5% 1 +[T51I,T747I] XBB.1.44.1 107 2 1.9% 1 +[H146K,T747I]-[H146Q] XBB.1.44.1 107 1 0.9% 2 +[T51I,T747I,P1079S] XBB.1.44.1 107 1 0.9% 9 +[T747I]-[L24-,P25-,P26-,A27S,V83A,Y144-,R346T,Q498R,Y505H] B.1.258.21 106 95 89.6% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.21 106 5 4.7% 1 +[H69-,V70-,S98F,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.21 106 1 0.9% 1 +[H69-,V70-,T95I,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.21 106 1 0.9% 1 +[H69-,V70-,N439K,D950Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.21 106 1 0.9% 1 +[H69-,V70-,N439K,K1181I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.2 106 83 78.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A522P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BQ.2 106 11 10.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A522P,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.2 106 5 4.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A522P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.2 106 1 0.9% 1 +[H69-,V70-,S112L,V213G,G339D,K444T,L452R,F486V,A522P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.2 106 1 0.9% 2 +[H69-,V70-,V213G,G261C,G339D,K444T,L452R,F486V,A522P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.160.12 106 96 90.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.12 106 2 1.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.12 106 2 1.9% 1 +[H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.12 106 1 0.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.12 106 1 0.9% 2 +[G257V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.453 106 97 91.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.453 106 3 2.8% 1 +[K558N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.453 106 2 1.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.453 106 1 0.9% 1 +[P384S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.453 106 1 0.9% 1 +[K300R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.3.8 106 68 64.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.8 106 13 12.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T678A,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.8 106 4 3.8% 3 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.1.3.8 106 4 3.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.3.8 106 3 2.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,P621S,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBB.1.5.22 106 27 25.5% 0 +[H146K]-[H146Q] (consensus) XBB.1.5.22 106 25 23.6% 1 +[H146K,T1136A]-[H146Q] XBB.1.5.22 106 15 14.2% 1 +[H146K,N282K]-[H146Q] XBB.1.5.22 106 4 3.8% 2 +[H146K,N282K,S689I]-[H146Q] XBB.1.5.22 106 4 3.8% 2 -[Y144-] XBB.3.2 105 59 56.2% 0 +[M177T,F486S]-[G252V,F486P] (consensus) XBB.3.2 105 6 5.7% 1 +[R78K,M177T,F486S]-[G252V,F486P] XBB.3.2 105 5 4.8% 2 +[M177T,F486S,D1153Y,K1245R]-[G252V,F486P] XBB.3.2 105 4 3.8% 1 +[M177T,F486S]-[G252V,K417N,F486P] XBB.3.2 105 3 2.9% 1 +[L5F,M177T,F486S]-[G252V,F486P] FL.4.3 105 26 24.8% 0 +[A766S] (consensus) FL.4.3 105 17 16.2% 1 +[A766S,I1114T] FL.4.3 105 11 10.5% 1 +[G482R,A766S] FL.4.3 105 10 9.5% 1 +[A766S]-[T19I] FL.4.3 105 8 7.6% 1 +[E554Q,A766S] XBB.1.5.41 105 65 61.9% 0 +[P521T,V772I] (consensus) XBB.1.5.41 105 14 13.3% 1 +[S494P,P521T,V772I] XBB.1.5.41 105 3 2.9% 1 +[P521T,V772I,V952I] XBB.1.5.41 105 3 2.9% 1 +[P521T,V772I,Q1201E] XBB.1.5.41 105 3 2.9% 1 +[Q23R,P521T,V772I] JK.1 105 74 70.5% 0 +[K304Q,A411S] (consensus) JK.1 105 7 6.7% 1 +[K304Q,A411S,P1162L] JK.1 105 5 4.8% 1 +[K304Q,A411S,C1243F] JK.1 105 4 3.8% 1 +[K304Q,A411S]-[K417N] JK.1 105 3 2.9% 1 +[K304Q,A411S,E554K] JN.1.11 104 47 45.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.11 104 10 9.6% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.11 104 3 2.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S637Y,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.11 104 2 1.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.11 104 2 1.9% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBB.1.5.88 104 69 66.3% 0 (consensus) XBB.1.5.88 104 3 2.9% 2 +[H146K,E583D]-[H146Q] XBB.1.5.88 104 3 2.9% 1 +[G485S] XBB.1.5.88 104 3 2.9% 1 +[R190T] XBB.1.5.88 104 3 2.9% 1 -[R408S] B.1.1.57 104 63 60.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.57 104 13 12.5% 1 +[D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.57 104 4 3.8% 1 +[Q239R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.57 104 2 1.9% 1 +[I909V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.57 104 2 1.9% 1 +[G261C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.167 104 84 80.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.167 104 15 14.4% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.167 104 2 1.9% 1 +[M740I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.167 104 1 1.0% 1 +[D389E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.167 104 1 1.0% 1 +[T719I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KP.1 104 78 75.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KP.1 104 9 8.7% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KP.1 104 4 3.8% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KP.1 104 3 2.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,C1254F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KP.1 104 2 1.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] DK.1 104 91 87.5% 0 +[H69-,V70-,V213G,G339N,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DK.1 104 4 3.8% 1 +[H69-,V70-,V213G,G339N,K444T,L452R,F486V,N703S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DK.1 104 2 1.9% 1 +[H69-,V70-,V213G,G261V,G339N,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DK.1 104 1 1.0% 4 +[A27-,I68-,H69-,V213G,G339N,K444T,L452R,F486V]-[P25-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DK.1 104 1 1.0% 1 +[H69-,V70-,E132K,V213G,G339N,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.3 104 84 80.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704T]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EF.3 104 4 3.8% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704T]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.3 104 2 1.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704T,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.3 104 1 1.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704T]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EF.3 104 1 1.0% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704T]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BU.2 104 56 53.8% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BU.2 104 34 32.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,V1189I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BU.2 104 3 2.9% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BU.2 104 2 1.9% 2 +[H69-,V70-,V213G,G339D,V445A,L452R,T478E,F486V,V1189I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BU.2 104 1 1.0% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,K814T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.31 104 55 52.9% 0 (consensus) FL.31 104 10 9.6% 1 +[S494P] FL.31 104 4 3.8% 1 +[H146K]-[H146Q] FL.31 104 3 2.9% 1 +[F157S] FL.31 104 2 1.9% 2 -[V83A,Y505H] B.1.1.462 103 86 83.5% 0 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.462 103 6 5.8% 1 +[P384L,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.462 103 1 1.0% 1 +[S305F,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.462 103 1 1.0% 1 +[A522P,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.462 103 1 1.0% 1 +[K77N,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DV.6.1 103 36 35.0% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.6.1 103 17 16.5% 1 +[K147E,W152R,F157L,N185D,R190K,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.6.1 103 11 10.7% 1 +[K147E,W152R,M153I,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.6.1 103 6 5.8% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,H1101Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.6.1 103 5 4.9% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,R765H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.40 103 91 88.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.40 103 2 1.9% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.40 103 1 1.0% 1 +[V213G,G339D,Q493R,V1104L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.40 103 1 1.0% 1 +[K182T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.40 103 1 1.0% 1 +[V213G,G339D,Q493R,Q675K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.214.4 103 100 97.1% 0 +[T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.214.4 103 1 1.0% 1 +[T678I,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.4 103 1 1.0% 1 +[S689I,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.4 103 1 1.0% 1 +[H146-,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.31 102 97 95.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.31 102 2 2.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.31 102 1 1.0% 1 +[C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.31 102 1 1.0% 1 +[D808H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.31 102 1 1.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.600 102 64 62.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.600 102 6 5.9% 1 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.600 102 4 3.9% 1 +[V1065L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.600 102 3 2.9% 1 +[F186S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.600 102 3 2.9% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.270 102 96 94.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.270 102 5 4.9% 2 +[H146Y,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.270 102 1 1.0% 1 +[R847T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.14 102 46 45.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.14 102 13 12.7% 1 +[+16MPLF,R21T,S50L,S60A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.14 102 5 4.9% 1 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.14 102 3 2.9% 1 +[+16MPLF,R21T,V36I,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.14 102 2 2.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.118 102 45 44.1% 0 +[I805V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.118 102 27 26.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.118 102 12 11.8% 2 +[G181R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.118 102 7 6.9% 2 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.118 102 3 2.9% 1 +[D138Y,I805V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GY.8 102 77 75.5% 0 +[E180V,F456L,T478R]-[T478K] (consensus) GY.8 102 5 4.9% 1 +[E180V,F456L,T478R,F490P]-[T478K,F490S] GY.8 102 5 4.9% 1 +[E180V,S256L,F456L,T478R]-[T478K] GY.8 102 3 2.9% 1 +[E180V,A222V,F456L,T478R]-[T478K] GY.8 102 2 2.0% 1 +[D80G,E180V,F456L,T478R]-[T478K] B.1.120 102 100 98.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.120 102 1 1.0% 1 +[P26S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.120 102 1 1.0% 1 +[D839Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AZ.2.1 101 90 89.1% 0 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AZ.2.1 101 4 4.0% 1 +[T95I,E484K,D796H,A1226V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.2.1 101 2 2.0% 1 +[T95I,E484K,T678I,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.2.1 101 2 2.0% 1 +[P9-,T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.2.1 101 1 1.0% 2 +[T95I,E484K,D796H,P1143L,A1226V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] DH.1 101 96 95.0% 0 +[H69-,V70-,H146-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DH.1 101 1 1.0% 2 +[H69-,V70-,H146-,I210T,V213G,G339D,L452R,F486V,R683W]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DH.1 101 1 1.0% 1 +[H69-,V70-,H146-,V213G,G339D,L452R,F486V,A852V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DH.1 101 1 1.0% 2 +[H69-,V70-,H146-,V213G,G339D,L452R,F486V,A845V,D1139H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DH.1 101 1 1.0% 1 +[H69-,V70-,H146-,V213G,G339D,L452R,F486V,D1139N]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DA.1 101 45 44.6% 0 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DA.1 101 23 22.8% 1 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] DA.1 101 3 3.0% 1 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DA.1 101 3 3.0% 1 +[H69-,V70-,V213G,G261S,G339D,T430I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DA.1 101 3 3.0% 2 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.36.10 101 65 64.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.10 101 10 9.9% 1 +[C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.10 101 5 5.0% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.10 101 3 3.0% 2 +[G446V,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.10 101 2 2.0% 1 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAT 101 67 66.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAT 101 20 19.8% 1 +[V213G,G339D,Q493R,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAT 101 5 5.0% 2 +[L5F,V213G,T323I,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAT 101 5 5.0% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAT 101 1 1.0% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.606 100 97 97.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.606 100 1 1.0% 1 +[C480F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.606 100 1 1.0% 1 +[I105L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.606 100 1 1.0% 2 +[A243-,L244-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.89 100 89 89.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.89 100 3 3.0% 1 +[T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.89 100 2 2.0% 1 +[V1228I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.89 100 1 1.0% 1 +[D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.89 100 1 1.0% 1 +[T299A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.19 100 65 65.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.19 100 6 6.0% 2 +[A222P,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.19 100 4 4.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.19 100 3 3.0% 1 +[F140L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.19 100 2 2.0% 1 +[T719I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.495 100 89 89.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.495 100 3 3.0% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.495 100 2 2.0% 1 +[V382L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.495 100 2 2.0% 1 +[E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.495 100 1 1.0% 2 +[Q173R,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.201 100 65 65.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.201 100 21 21.0% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.201 100 4 4.0% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.201 100 2 2.0% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.201 100 2 2.0% 1 +[R408I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.86.2 100 37 37.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) BA.2.86.2 100 20 20.0% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.2 100 2 2.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,S155I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.2 100 2 2.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.2 100 2 2.0% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBB.2.3.13 100 61 61.0% 0 +[D253G,P521S]-[G252V] (consensus) XBB.2.3.13 100 6 6.0% 17 +[F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBB.2.3.13 100 5 5.0% 1 +[D253G,P521S,A701V]-[G252V] XBB.2.3.13 100 2 2.0% 1 +[D253G,N354K,P521S]-[G252V] XBB.2.3.13 100 2 2.0% 1 +[D253G]-[G252V] B.1.1.315 99 86 86.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.315 99 4 4.0% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.315 99 2 2.0% 1 +[Q14H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.315 99 1 1.0% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.315 99 1 1.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.2.5 99 61 61.6% 0 +[Q314E] (consensus) FL.2.5 99 17 17.2% 1 +[Q314E,I870V] FL.2.5 99 7 7.1% 1 +[Q314E,D745G] FL.2.5 99 2 2.0% 1 +[Q314E,P793L] FL.2.5 99 2 2.0% 2 +[Q314E,D820N,I870V] EG.11 99 78 78.8% 0 +[E554K] (consensus) EG.11 99 4 4.0% 1 EG.11 99 2 2.0% 1 +[T286I,E554K] EG.11 99 2 2.0% 1 +[L5F,E554K] EG.11 99 1 1.0% 2 -[N764K] HG.2 99 91 91.9% 0 +[D253G,T259I,T478R,P521S]-[G252V,T478K] (consensus) HG.2 99 1 1.0% 1 +[D253G,T259I,T478R,G482D,P521S]-[G252V,T478K] HG.2 99 1 1.0% 1 +[D253G,T259I,T478R,P521S,E1150K]-[G252V,T478K] HG.2 99 1 1.0% 1 +[D253G,T259I,T307I,T478R,P521S]-[G252V,T478K] HG.2 99 1 1.0% 3 +[D253G,T259I,S375-,T376-,F377-,T478R,P521S]-[G252V,S375F,T376A,T478K] FL.23.1 99 27 27.3% 0 (consensus) FL.23.1 99 23 23.2% 1 +[R214P] FL.23.1 99 10 10.1% 1 -[G142D] FL.23.1 99 8 8.1% 1 +[G798S] FL.23.1 99 7 7.1% 2 +[F157L,R214P] DJ.1 99 45 45.5% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] (consensus) DJ.1 99 14 14.1% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DJ.1 99 5 5.1% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,D568G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DJ.1 99 4 4.0% 2 +[H69-,V70-,K147N,V213G,G339D,D420N,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] DJ.1 99 3 3.0% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,N679R,D745A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S,N679K] CD.2 98 85 86.7% 0 +[H69-,V70-,L84I,V213G,G339D,A435S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CD.2 98 2 2.0% 1 +[H69-,V70-,L84I,V213G,G339D,R346I,A435S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CD.2 98 2 2.0% 1 +[H69-,V70-,L84I,V213G,G339D,A435S,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CD.2 98 2 2.0% 1 +[H69-,V70-,L84I,V213G,G339D,A435S,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CD.2 98 1 1.0% 1 +[H69-,V70-,L84I,V213G,G339D,A435S,L452R,F486V,T1136K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CY.1 98 69 70.4% 0 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CY.1 98 12 12.2% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CY.1 98 2 2.0% 1 +[H69-,V70-,K147I,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CY.1 98 2 2.0% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] CY.1 98 2 2.0% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V,P521L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EG.4.3 98 36 36.7% 0 +[I128V,Q613H] (consensus) EG.4.3 98 22 22.4% 1 +[Q613H] EG.4.3 98 4 4.1% 2 +[F157L,Q613H] EG.4.3 98 4 4.1% 3 +[L5F,T573I,Q613H] EG.4.3 98 2 2.0% 2 +[F140S,Q613H] JN.1.4.1 98 57 58.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E654V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.4.1 98 17 17.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E654V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.1 98 5 5.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E654V,P681R,S939F,P1143L,I1198V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.1 98 3 3.1% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E654V,P681R,S939F,P1143L,L1244F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.4.1 98 2 2.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,E654V,P681R,A845V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] W.1 98 58 59.2% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) W.1 98 4 4.1% 1 +[A67V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.1 98 4 4.1% 4 +[Y28H,A222V,S255F,A520S,A688S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.1 98 2 2.0% 1 +[A222V,S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.1 98 2 2.0% 1 +[A222V,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.1 98 73 74.5% 0 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.466.1 98 8 8.2% 1 +[L5F,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.1 98 6 6.1% 1 +[N439K,D1118G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.1 98 2 2.0% 1 +[I434V,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.1 98 2 2.0% 1 +[L7F,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.1 98 24 24.5% 0 +[A222V,A672V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.1 98 19 19.4% 2 +[A222V,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AA.1 98 13 13.3% 3 +[T19K,A222V,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.1 98 7 7.1% 4 +[A222V,N540K,Q677H,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.1 98 7 7.1% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.27 98 61 62.2% 0 +[A222V,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.27 98 33 33.7% 1 +[A222V,Q613H,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.27 98 1 1.0% 1 +[T22I,A222V,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.27 98 1 1.0% 1 +[A222V,L517F,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.27 98 1 1.0% 1 +[A222V,Q613H,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.10 97 91 93.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.10 97 2 2.1% 1 +[D1127G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.10 97 1 1.0% 1 +[P809L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.10 97 1 1.0% 1 +[V407I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.10 97 1 1.0% 1 +[H1271N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GA.1 97 38 39.2% 0 +[D215H] (consensus) GA.1 97 17 17.5% 1 +[L5F,D215H] GA.1 97 8 8.2% 2 +[D215H,S254F,P1263L] GA.1 97 6 6.2% 1 +[D215H,D428Y] GA.1 97 4 4.1% 1 +[D215H,V622A] B.1.1.261 97 69 71.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.261 97 6 6.2% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.261 97 2 2.1% 2 +[Q677H,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.261 97 2 2.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.261 97 2 2.1% 1 +[G1099D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.209 97 37 38.1% 0 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.209 97 35 36.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.209 97 20 20.6% 2 +[Y508H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.209 97 2 2.1% 1 +[T95I,T573I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.209 97 1 1.0% 1 +[T95I,S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.336 97 79 81.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.336 97 2 2.1% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.336 97 1 1.0% 1 +[S1147L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.336 97 1 1.0% 1 +[F1103L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.336 97 1 1.0% 2 +[A419G,N437S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.2.82 97 71 73.2% 0 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.82 97 15 15.5% 1 +[L5F,I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.82 97 2 2.1% 1 +[I68T,V213G,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.82 97 1 1.0% 1 +[I68T,V213G,T299I,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.82 97 1 1.0% 1 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,N764K] BN.1.3.9 97 77 79.4% 0 +[V83F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.9 97 5 5.2% 1 +[V83F,K147E,W152R,F157L,I210V,V213G,A222V,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.9 97 4 4.1% 1 +[L5F,V83F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.9 97 3 3.1% 1 +[V83F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q1180E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.9 97 1 1.0% 1 +[V83F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,T1117I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] JC.1 97 64 66.0% 0 +[K77R,L335S,R403K,T478R]-[T478K] (consensus) JC.1 97 7 7.2% 1 +[K77R,L335S,R403K,T478R,A942S]-[T478K] JC.1 97 5 5.2% 1 +[K77R,N148T,L335S,R403K,T478R]-[T478K] JC.1 97 3 3.1% 1 +[K77R,L335S,R403K,T478R,E654Q]-[T478K] JC.1 97 3 3.1% 2 +[L5F,K77R,L335S,R403K,T478R,A942S]-[T478K] BF.7.14.2 97 73 75.3% 0 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14.2 97 4 4.1% 2 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,Q607R,D936E,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.2 97 4 4.1% 2 +[Q14H,H69-,V70-,M153I,V213G,G339D,L452R,F486V,R683Q,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.2 97 2 2.1% 1 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,A1020S,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.2 97 2 2.1% 1 +[Q14H,H69-,V70-,V213G,G252S,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.41 97 52 53.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.41 97 25 25.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.41 97 11 11.3% 1 +[V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.41 97 3 3.1% 1 +[G252S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.41 97 1 1.0% 1 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.2.4 97 89 91.8% 0 +[K356T,T478R]-[T478K] (consensus) EG.2.4 97 3 3.1% 1 +[H146K,K356T,T478R]-[H146Q,T478K] EG.2.4 97 1 1.0% 1 +[K356T,T385I,T478R]-[T478K] EG.2.4 97 1 1.0% 1 +[A67V,K356T,T478R]-[T478K] EG.2.4 97 1 1.0% 1 +[I332T,K356T,T478R]-[T478K] B.1.214.3 96 61 63.5% 0 +[T95I,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.214.3 96 12 12.5% 1 +[T95I,Q628K,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.3 96 6 6.2% 1 +[T95I,E484K,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.3 96 3 3.1% 1 +[T95I,Q271E,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.3 96 3 3.1% 2 +[T95I,Q613H,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.30 96 57 59.4% 0 +[F486S]-[F486P] (consensus) XBB.1.30 96 17 17.7% 1 XBB.1.30 96 4 4.2% 1 +[F486S]-[G252V,F486P] XBB.1.30 96 4 4.2% 1 +[A67V,F486S]-[F486P] XBB.1.30 96 3 3.1% 1 +[F486S]-[K417N,F486P] B.1.36.33 96 93 96.9% 0 +[I210-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.33 96 2 2.1% 1 +[I210-,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.33 96 1 1.0% 2 +[I210-,P384L,I1018M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.61 96 85 88.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.61 96 3 3.1% 1 +[T1160I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.61 96 2 2.1% 1 +[Q926H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.61 96 1 1.0% 1 +[R102S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.61 96 1 1.0% 1 +[G261V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.7 96 83 86.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.4.7 96 5 5.2% 2 +[A575S,A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.7 96 2 2.1% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.7 96 1 1.0% 1 +[I468V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.7 96 1 1.0% 1 +[T299I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AT.1 96 75 78.1% 0 +[P9L,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,D215G,H245P,E484K,+679GIAL,E780K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] (consensus) AT.1 96 3 3.1% 14 +[P9L,D215G,H245P,E484K,E780K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AT.1 96 3 3.1% 1 +[P9L,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,H245P,E484K,+679GIAL,E780K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] AT.1 96 3 3.1% 1 +[P9L,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,D215G,H245P,E484K,+679GIAL,E780K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,P681H,N764K,D796Y,Q954H,N969K] AT.1 96 2 2.1% 1 +[P9L,P26S,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,D215G,H245P,E484K,+679GIAL,E780K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] GN.4 96 73 76.0% 0 (consensus) GN.4 96 3 3.1% 1 -[R408S] GN.4 96 3 3.1% 1 +[H146K]-[H146Q] GN.4 96 2 2.1% 1 +[T1117I] GN.4 96 2 2.1% 2 +[N481K,V1128I] B.1.44 96 72 75.0% 0 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.44 96 22 22.9% 1 +[G769V,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.44 96 1 1.0% 2 +[G769V,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.44 96 1 1.0% 1 +[L54F,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.27 96 75 78.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.27 96 4 4.2% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.27 96 3 3.1% 1 +[R21T,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.27 96 2 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.27 96 1 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,D1260Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] GK.4 96 82 85.4% 0 +[L455F,F456L,A475V] (consensus) GK.4 96 3 3.1% 1 +[A348S,L455F,F456L,A475V] GK.4 96 1 1.0% 8 +[D138Q,P139-,F140-,L141-,G142-,V143-,Y145-,H146-,L455F,F456L,A475V]-[G142D,H146Q] GK.4 96 1 1.0% 2 +[S151I,P272L,L455F,F456L,A475V] GK.4 96 1 1.0% 1 +[L455F,F456L,A475V]-[T19I] B.1.1.115 95 44 46.3% 0 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.115 95 43 45.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.115 95 2 2.1% 1 +[L5F,S12F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.115 95 2 2.1% 2 +[S1239I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.115 95 1 1.1% 2 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.78 95 82 86.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.78 95 3 3.2% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.78 95 2 2.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.78 95 1 1.1% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.78 95 1 1.1% 2 +[L5F,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FY.2.1 95 77 81.1% 0 +[I197T,Y200C,A684V] (consensus) FY.2.1 95 8 8.4% 1 +[I197T,Y200C,A684V,V1228L] FY.2.1 95 2 2.1% 1 +[I197T,Y200C,A684V]-[K417N] FY.2.1 95 1 1.1% 4 +[I197T,Y200C,A684V]-[L24-,P25-,P26-,A27S] FY.2.1 95 1 1.1% 1 +[I197T,Y200C,A684V,L1063F] BA.2.75.7 95 37 38.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BA.2.75.7 95 20 21.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.7 95 3 3.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,T1009I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.7 95 2 2.1% 3 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.7 95 2 2.1% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BM.1 95 41 43.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BM.1 95 9 9.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1 95 7 7.4% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,N450D,F486S,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BM.1 95 6 6.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,R346S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BM.1 95 4 4.2% 3 +[N99D,K147E,W152R,F157L,N185D,I210V,V213G,G257S,N450D,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] B.1.591 94 81 86.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.591 94 3 3.2% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.591 94 2 2.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.591 94 2 2.1% 1 +[S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.591 94 1 1.1% 2 +[Y473F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.213 94 68 72.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.213 94 9 9.6% 1 +[S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.213 94 3 3.2% 1 +[T547I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.213 94 3 3.2% 2 +[T51I,S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.213 94 2 2.1% 1 +[L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.265 94 30 31.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.265 94 26 27.7% 1 +[P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.265 94 11 11.7% 2 +[F643L,E1207D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.265 94 5 5.3% 2 +[T29I,D808E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.265 94 3 3.2% 2 +[P384L,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GW.2 94 77 81.9% 0 +[E554K,D936G] (consensus) GW.2 94 3 3.2% 1 +[E554K,D936G,P1162L] GW.2 94 2 2.1% 1 +[E554K,D936G]-[R408S] GW.2 94 2 2.1% 1 +[H146K,E554K,D936G]-[H146Q] GW.2 94 2 2.1% 1 +[E554K,D936G,S1252F] BQ.1.1.62 94 68 72.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.62 94 5 5.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.62 94 4 4.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621S,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.62 94 3 3.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621S,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.62 94 3 3.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] HC.2 93 73 78.5% 0 +[F157L,K356T,T572I] (consensus) HC.2 93 3 3.2% 2 +[F157L,K356T,D420N,T572I]-[R408S] HC.2 93 2 2.2% 1 +[F157L,A352V,K356T,T572I] HC.2 93 2 2.2% 1 +[F157L,K356T,T572I]-[D796Y] HC.2 93 2 2.2% 1 +[F157L,S221L,K356T,T572I] B.1.1.380 93 86 92.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.380 93 3 3.2% 1 +[D1259V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.380 93 2 2.2% 1 +[M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.380 93 1 1.1% 1 +[L226V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.380 93 1 1.1% 3 +[T76I,S967N,I1179T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.12 93 82 88.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.12 93 3 3.2% 1 +[W258L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.12 93 3 3.2% 1 +[R1091L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.12 93 2 2.2% 2 +[V143D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.12 93 1 1.1% 1 +[E516Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.116 93 90 96.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.116 93 1 1.1% 1 +[T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.116 93 1 1.1% 1 +[K77N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.116 93 1 1.1% 1 +[T588I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.35 93 87 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.35 93 2 2.2% 1 +[M869I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.35 93 2 2.2% 1 +[E554D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.35 93 1 1.1% 1 +[A348S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.35 93 1 1.1% 1 +[G482S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FE.1.1.3 93 70 75.3% 0 +[F456L] (consensus) FE.1.1.3 93 5 5.4% 1 +[F456L,T883I] FE.1.1.3 93 4 4.3% 1 +[Q52R,F456L] FE.1.1.3 93 2 2.2% 2 +[L455F,F456L,L513I] FE.1.1.3 93 1 1.1% 1 +[V213G,F456L]-[V213E] B.1.330 93 83 89.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.330 93 2 2.2% 1 +[S1252C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.330 93 1 1.1% 1 +[P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.330 93 1 1.1% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.330 93 1 1.1% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.18 93 57 61.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.18 93 19 20.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,E1150D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.18 93 8 8.6% 1 +[T19R,E156G,F157-,R158-,L452R,V622F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.18 93 6 6.5% 1 +[T19R,E156G,F157-,R158-,V289I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.18 93 2 2.2% 1 +[T19R,E156G,F157-,R158-,R214H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.428 92 81 88.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.428 92 3 3.3% 1 +[P681S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.428 92 3 3.3% 1 +[A845V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.428 92 2 2.2% 1 +[R646H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.428 92 1 1.1% 1 +[S1249F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.187 92 64 69.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.187 92 15 16.3% 1 +[D936E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.187 92 6 6.5% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.187 92 2 2.2% 1 -[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.187 92 1 1.1% 1 +[H245Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.4 92 79 85.9% 0 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2.4 92 6 6.5% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.4 92 2 2.2% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,D1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.4 92 1 1.1% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,E1150A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.4 92 1 1.1% 2 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] CJ.1.3.1 92 78 84.8% 0 +[K147E,W152R,F157L,I210V,V213G,R214S,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) CJ.1.3.1 92 3 3.3% 1 +[K147E,W152R,F157L,I210V,V213G,R214S,G257S,V362F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3.1 92 2 2.2% 1 +[K147E,W152R,F157L,I210V,V213G,R214S,G257S,G446T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S] CJ.1.3.1 92 1 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,R214S,G257S,G1219C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3.1 92 1 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,R214S,G257S,T1238N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBB.1.4.2 92 27 29.3% 0 +[T883I] XBB.1.4.2 92 14 15.2% 2 +[T883I]-[R346T,K417N] XBB.1.4.2 92 14 15.2% 1 +[T883I]-[R346T] (consensus) XBB.1.4.2 92 4 4.3% 1 +[L249M,T883I] XBB.1.4.2 92 3 3.3% 3 +[T883I]-[G142D,R346T,K417N] B.1.177.3 92 91 98.9% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.3 92 1 1.1% 1 +[A222V,S810L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.38 91 73 80.2% 0 +[A222V,K1045N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.38 91 6 6.6% 1 +[A222V,K1045N,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.38 91 3 3.3% 1 +[A222V,T678I,K1045N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.38 91 3 3.3% 1 +[A222V,K795N,K1045N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.38 91 2 2.2% 2 +[A222V,G261V,T678I,K1045N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JM.2 91 66 72.5% 0 +[R78S,K147N,E180V,T478R,P521S]-[T478K] (consensus) JM.2 91 7 7.7% 2 +[R78S,K147N,E180V,T478R,P521S,A845V,D1146H]-[T478K] JM.2 91 2 2.2% 1 +[R78S,K147N,E180V,T478R,P521S,V551I]-[T478K] JM.2 91 2 2.2% 1 +[R78S,K147N,E180V,T478R]-[T478K] JM.2 91 1 1.1% 1 +[R78S,K147N,E180V,T478R,P521S,S884F]-[T478K] BF.34 91 70 76.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,R646H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.34 91 10 11.0% 1 +[H69-,V70-,V213G,G257S,G339D,L452R,F486V,R646H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.34 91 3 3.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,R646H,A846V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.34 91 2 2.2% 1 +[H69-,V70-,K187R,V213G,G339D,L452R,F486V,R646H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.34 91 2 2.2% 1 +[H69-,V70-,V213G,P251R,G339D,L452R,F486V,R646H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.1.4 91 59 64.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.1.4 91 5 5.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,D178E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.4 91 4 4.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.4 91 2 2.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677R,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.4 91 2 2.2% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBF.7 91 59 64.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.7 91 5 5.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L1197F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.7 91 4 4.4% 3 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P] XBF.7 91 3 3.3% 1 +[H146N,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.7 91 3 3.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,A520S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] GY.2.1 91 73 80.2% 0 +[E180V,S255F,T478R,T883I]-[T478K] (consensus) GY.2.1 91 5 5.5% 1 +[H146K,E180V,S255F,T478R,T883I]-[H146Q,T478K] GY.2.1 91 2 2.2% 1 +[E180V,S255F,T478R,Q613H,T883I]-[T478K] GY.2.1 91 2 2.2% 1 +[E180V,S255F,T478R,T883I]-[R408S,T478K] GY.2.1 91 2 2.2% 1 +[E180V,S255F,T478R,T883I,I1225F]-[T478K] FL.15.3 91 71 78.0% 0 +[G181V,F456L] (consensus) FL.15.3 91 5 5.5% 1 +[L5F,G181V,F456L] FL.15.3 91 2 2.2% 1 +[G181V,F456L,T547K] FL.15.3 91 2 2.2% 2 +[H146K,G181V,F456L,N481K]-[H146Q] FL.15.3 91 1 1.1% 2 +[L5F,G181V,F456L,F797L] FL.4.9 91 66 72.5% 0 +[S254P] (consensus) FL.4.9 91 6 6.6% 1 +[S254P,T678I] FL.4.9 91 3 3.3% 1 +[L229F,S254P] FL.4.9 91 3 3.3% 1 +[S254P,A688V] FL.4.9 91 2 2.2% 1 +[S254P,L335F] XAK 91 72 79.1% 0 +[H69-,V70-,K147E,V213G,G339D,R346K,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) XAK 91 8 8.8% 1 +[H69-,V70-,K147E,V213G,G339D,R346K,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,F486P,F490S] XAK 91 2 2.2% 2 +[H69-,V70-,K147E,V213G,G339D,R346K,H1101Y,Q1180E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,F486P,F490S] XAK 91 2 2.2% 1 +[H69-,V70-,K147E,V213G,G339D,R346K,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] XAK 91 2 2.2% 1 +[H69-,V70-,K147E,V213G,G339D,R346K,V483L,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] C.3 91 86 94.5% 0 +[V213L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.3 91 2 2.2% 1 +[L5F,V213L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.3 91 1 1.1% 1 +[V213L,D1168Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.3 91 1 1.1% 1 +[V213L,E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.3 91 1 1.1% 1 +[G184V,V213L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.339 90 80 88.9% 0 +[I870V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.339 90 3 3.3% 1 +[G769V,I870V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.339 90 3 3.3% 1 +[I870V,M900I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.339 90 1 1.1% 1 +[E224Q,I870V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.339 90 1 1.1% 1 +[L5F,I870V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.11 90 53 58.9% 0 +[T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.11 90 8 8.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.11 90 6 6.7% 1 +[T95I,T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.11 90 3 3.3% 1 +[R246T,T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.11 90 2 2.2% 1 +[T307I,P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.603 90 55 61.1% 0 +[N370S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.603 90 21 23.3% 1 +[S12F,N370S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.603 90 3 3.3% 1 +[N370S,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.603 90 3 3.3% 1 +[L5F,N370S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.603 90 1 1.1% 2 +[N370S,T572I,S704A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.630 90 62 68.9% 0 +[P9L,C136F,A222V,A243-,L244-,L452R,T478R,E484Q,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.630 90 3 3.3% 1 +[P9L,A222V,A243-,L244-,L452R,T478R,E484Q,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.630 90 3 3.3% 1 +[P9L,C136F,A222V,A243-,L244-,R346K,L452R,T478R,E484Q,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.630 90 2 2.2% 1 +[P9L,C136F,A222V,A243-,L244-,D427N,L452R,T478R,E484Q,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.630 90 2 2.2% 1 +[P9L,C136F,A222V,A243-,L244-,L452R,T478R,E484Q,Q677H,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] U.2 90 58 64.4% 0 +[L5F,L18F,W64C,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) U.2 90 25 27.8% 1 +[L5F,L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] U.2 90 6 6.7% 2 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] U.2 90 1 1.1% 4 +[L18F,P26S,A222V,T415N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.322 90 69 76.7% 0 +[T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.322 90 3 3.3% 1 +[D138H,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.322 90 2 2.2% 2 +[L18F,T732A,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.322 90 1 1.1% 2 +[D138H,D253G,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.322 90 1 1.1% 1 +[K129R,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JQ.1 90 56 62.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JQ.1 90 4 4.4% 4 +[R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JQ.1 90 2 2.2% 6 +[R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JQ.1 90 2 2.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1251V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JQ.1 90 1 1.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V382L,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] CJ.1.1 90 64 71.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) CJ.1.1 90 12 13.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,V445A,G798S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.1 90 6 6.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,V445A,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.1 90 1 1.1% 1 +[K147E,W152R,F157L,I210V,G257S,V445A]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P] CJ.1.1 90 1 1.1% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,V445A,+516V,H519-]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] B.1.1.236 90 89 98.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.236 90 1 1.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.190 90 83 92.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.190 90 2 2.2% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.190 90 1 1.1% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.190 90 1 1.1% 1 +[S1051T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.190 90 1 1.1% 1 +[A831T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.17.1 90 67 74.4% 0 +[N74H] (consensus) FL.17.1 90 9 10.0% 1 +[N74H]-[R408S] FL.17.1 90 3 3.3% 1 +[N74H,G184V] FL.17.1 90 2 2.2% 1 +[N74H,S151I] FL.17.1 90 2 2.2% 1 +[N74H,V367I] XBB.1.5.106 90 50 55.6% 0 +[A623V] (consensus) XBB.1.5.106 90 15 16.7% 1 +[A623V]-[K417N] XBB.1.5.106 90 3 3.3% 1 +[A623V]-[G142D] XBB.1.5.106 90 3 3.3% 3 +[F157S,K202N,K304N,A623V] XBB.1.5.106 90 3 3.3% 1 +[S155G,A623V] HU.1.1 89 63 70.8% 0 +[Y28H,E471Q,K529N] (consensus) HU.1.1 89 6 6.7% 1 +[Y28H,E471Q,K529N,N556K] HU.1.1 89 4 4.5% 1 +[Y28H,E471Q,K529N,L699I] HU.1.1 89 2 2.2% 1 +[Y28H,L189F,E471Q,K529N] HU.1.1 89 2 2.2% 1 +[L5F,Y28H,E471Q,K529N] XDK.1 89 79 88.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) XDK.1 89 1 1.1% 2 +[+16MPLF,R21T,S50L,H69-,V70-,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] XDK.1 89 1 1.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] XDK.1 89 1 1.1% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] XDK.1 89 1 1.1% 2 +[+16MPLF,R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[P25-,A27S,V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] XBB.1.7 89 68 76.4% 0 +[F486S,V608I]-[F486P] (consensus) XBB.1.7 89 5 5.6% 1 +[F486S,V608I,H1101Q]-[F486P] XBB.1.7 89 2 2.2% 2 +[F486S,V608I,S704L,G1251V]-[F486P] XBB.1.7 89 2 2.2% 1 +[F486S,V608I]-[K417N,F486P] XBB.1.7 89 1 1.1% 1 +[I197V,F486S,V608I]-[F486P] B.1.351.5 89 45 50.6% 0 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.351.5 89 10 11.2% 3 +[L18F,D80A,D215G,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.5 89 5 5.6% 2 +[L18F,D80A,D215G,L242P,A243-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.5 89 3 3.4% 1 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.5 89 2 2.2% 4 +[D80A,D215G,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GJ.1.2.5 89 56 62.9% 0 +[K182N,D253G,P521S,I834V]-[G252V] (consensus) GJ.1.2.5 89 14 15.7% 1 +[K182N,D253G,P521S,V622A,I834V]-[G252V] GJ.1.2.5 89 7 7.9% 1 +[K182N,D253G,Q493L,P521S,I834V]-[G252V] GJ.1.2.5 89 2 2.2% 1 +[K182N,D253G,P521S,V615I,I834V]-[G252V] GJ.1.2.5 89 1 1.1% 1 +[K182N,D253G,P521S,L552F,I834V]-[G252V] B.1.1.101 88 67 76.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.101 88 3 3.4% 1 +[Q14H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.101 88 2 2.3% 1 +[G72R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.101 88 2 2.3% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.101 88 2 2.3% 1 +[S704L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.543 88 61 69.3% 0 +[T95N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.543 88 11 12.5% 1 +[T95N,I233V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.543 88 5 5.7% 1 +[T95N,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.543 88 2 2.3% 1 +[V90I,T95N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.543 88 2 2.3% 1 +[T95N,A348S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23 88 65 73.9% 0 +[F157L,V367F,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.23 88 4 4.5% 1 +[F157L,E309K,V367F,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23 88 3 3.4% 1 +[F157L,V367F,Q613H,K1205N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23 88 3 3.4% 1 +[F157L,G184V,V367F,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23 88 3 3.4% 2 +[F157L,V367F,E484K,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.2 88 87 98.9% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AA.2 88 1 1.1% 1 +[A222V,L582F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.402 88 67 76.1% 0 +[T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.402 88 12 13.6% 1 +[T307I,V1104I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.402 88 2 2.3% 1 +[T307I,T1100A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.402 88 2 2.3% 1 +[L176F,T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.402 88 1 1.1% 1 +[T307I,I584T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.5 88 67 76.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.5 88 8 9.1% 1 +[R765H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.5 88 3 3.4% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.5 88 3 3.4% 1 +[M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.5 88 2 2.3% 1 +[D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.390 88 65 73.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.390 88 11 12.5% 3 +[F32L,Y144F,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.390 88 3 3.4% 2 +[H49Y,G1085L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.390 88 1 1.1% 1 +[I834T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.390 88 1 1.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.451 88 75 85.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.451 88 3 3.4% 2 +[A1020S,L1244F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.451 88 2 2.3% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.451 88 1 1.1% 1 +[T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.451 88 1 1.1% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] ER.1.1 88 76 86.4% 0 +[H69-,V70-,V213G,+255P,G257-,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) ER.1.1 88 3 3.4% 1 +[H69-,V70-,V213G,+255P,G257-,G339D,K444T,L452R,F486V,E654Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ER.1.1 88 2 2.3% 2 +[L5F,H69-,V70-,V213G,+255P,G257-,G339D,K444T,L452R,F486V,E654Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ER.1.1 88 2 2.3% 3 +[L5F,H69-,V70-,V213G,+255P,G257-,G339D,K444T,L452R,F486V,E654Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] ER.1.1 88 1 1.1% 1 +[H69-,V70-,V213G,+255P,G257-,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] FL.2.2.1 88 26 29.5% 0 +[T307I,T478R]-[T478K] (consensus) FL.2.2.1 88 20 22.7% 2 +[G75S,T307I,K356T,T478R]-[T478K] FL.2.2.1 88 7 8.0% 1 +[T307I,T478R,E554D]-[T478K] FL.2.2.1 88 5 5.7% 1 +[T307I,T478R,Q675L]-[T478K] FL.2.2.1 88 5 5.7% 1 +[T307I,T478R]-[K417N,T478K] DN.1.1.3 88 80 90.9% 0 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.1.1.3 88 1 1.1% 2 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] DN.1.1.3 88 1 1.1% 1 +[H69-,V70-,K147N,V213G,G252D,G339D,K444T,L452R,F486V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1.1.3 88 1 1.1% 1 +[H69-,V70-,V83F,K147N,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1.1.3 88 1 1.1% 10 +[V11I,S12-,S13-,Q14-,C15-,V16-,N17-,L18-,T20-,H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V,S704L]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.501 87 65 74.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.501 87 7 8.0% 1 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.501 87 3 3.4% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.501 87 3 3.4% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.501 87 2 2.3% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.15.3 87 73 83.9% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.15.3 87 2 2.3% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,L452R,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S,N764K] BA.1.15.3 87 2 2.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.3 87 2 2.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.15.3 87 1 1.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.1.117 87 75 86.2% 0 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.117 87 4 4.6% 2 +[L18F,T20P,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.117 87 2 2.3% 1 +[K558N,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.117 87 1 1.1% 1 +[S359N,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.117 87 1 1.1% 1 +[L585F,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CM.5.2 87 77 88.5% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.5.2 87 2 2.3% 1 +[K150N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.5.2 87 1 1.1% 2 +[K150N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.5.2 87 1 1.1% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D,I1216V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.5.2 87 1 1.1% 2 +[A27-,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[P25-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.8.1.1 87 75 86.2% 0 +[K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] (consensus) CM.8.1.1 87 6 6.9% 1 +[K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,D574Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.1 87 1 1.1% 1 +[P85S,K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.1 87 1 1.1% 1 +[K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,K986N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.1 87 1 1.1% 1 +[K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] BF.38.3 87 78 89.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] (consensus) BF.38.3 87 5 5.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] BF.38.3 87 2 2.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38.3 87 1 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G496S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] BF.38.3 87 1 1.1% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,S698L,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,D405N,V445P,G446S,N460K,F486P,F490S,H655Y] B.1.383 87 82 94.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.383 87 2 2.3% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.383 87 1 1.1% 1 +[R1014K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.383 87 1 1.1% 1 +[D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.383 87 1 1.1% 1 +[N450K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.37 86 58 67.4% 0 +[H69-,V70-,V213G,Y248N,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.37 86 6 7.0% 1 +[H69-,V70-,V213G,Y248N,E281G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.37 86 5 5.8% 1 +[H69-,V70-,V213G,Y248N,G339Y,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.37 86 3 3.5% 1 +[H69-,V70-,G181V,V213G,Y248N,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.37 86 1 1.2% 1 +[H69-,V70-,V213G,Y248N,G339D,L452R,F486V,A783S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.148 86 75 87.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.148 86 2 2.3% 1 +[D808H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.148 86 1 1.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.148 86 1 1.2% 2 +[D80A,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.148 86 1 1.2% 1 +[R847K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.220 86 76 88.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.220 86 3 3.5% 1 +[A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.220 86 2 2.3% 1 +[G1085L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.220 86 1 1.2% 1 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.220 86 1 1.2% 1 +[L1024F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAL 86 67 77.9% 0 +[L8F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAL 86 13 15.1% 1 +[L8F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] XAL 86 2 2.3% 1 +[L8F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAL 86 2 2.3% 2 +[L8F,V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAL 86 1 1.2% 1 +[L8F,V213G,G339D,Q493R,P681R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] DM.1 86 42 48.8% 0 +[H69-,V70-,V213G,G339D,A348S,K444T,L452R,F486V,G1171A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DM.1 86 22 25.6% 1 +[H69-,V70-,V213G,G339D,A348S,K444T,L452R,F486V,G1171A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DM.1 86 7 8.1% 1 +[H69-,V70-,V213G,G339D,A348S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DM.1 86 2 2.3% 1 +[H69-,V70-,V213G,G339D,A348S,K444T,L452R,F486V,G1171A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] DM.1 86 2 2.3% 2 +[H69-,V70-,V213G,G339D,A348S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BR.5 86 76 88.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BR.5 86 3 3.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,D574V,I1232T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.5 86 2 2.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,F486P,F490S] BR.5 86 1 1.2% 5 +[I210V,V213G,G257S,K444T,L452R,D574V,I1232T]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.5 86 1 1.2% 1 +[R21T,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BF.19 86 59 68.6% 0 +[H69-,V70-,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.19 86 5 5.8% 1 +[Y28C,H69-,V70-,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.19 86 3 3.5% 2 +[L5F,H69-,V70-,G339D,L452R,F486V,C1235F]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.19 86 3 3.5% 1 +[H69-,V70-,G339D,L452R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.19 86 2 2.3% 1 +[H69-,V70-,G339D,L452R,F486V,P561S]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.36.12 86 71 82.6% 0 +[V1068F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.12 86 7 8.1% 1 +[S939F,V1068F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.12 86 2 2.3% 1 +[V1068F,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.12 86 1 1.2% 3 +[I210-,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.12 86 1 1.2% 2 +[K814R,S939F,V1068F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.533 85 39 45.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.533 85 3 3.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.533 85 2 2.4% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.533 85 1 1.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.533 85 1 1.2% 4 +[T95I,D253G,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.9 85 74 87.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.9 85 1 1.2% 2 +[A263T,T618I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.9 85 1 1.2% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.9 85 1 1.2% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.9 85 1 1.2% 2 +[L8F,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XDD.1 85 38 44.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDD.1 85 12 14.1% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD.1 85 11 12.9% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD.1 85 4 4.7% 6 +[R21T,A27-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD.1 85 2 2.4% 7 +[R21T,S50L,H69-,V70-,S98F,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] GJ.1.2.6 85 27 31.8% 0 +[K182N,D253G,T478R,P521S]-[G252V,T478K] (consensus) GJ.1.2.6 85 12 14.1% 2 +[K97N,K182N,D253G,F456L,T478R,P521S]-[G252V,T478K] GJ.1.2.6 85 7 8.2% 2 +[K182N,D253G,T478R,P521S,E554V,Q675H]-[G252V,T478K] GJ.1.2.6 85 5 5.9% 3 +[K97N,H146K,K182N,D253G,F456L,T478R,P521S]-[H146Q,G252V,T478K] GJ.1.2.6 85 4 4.7% 2 +[K150I,K182N,D253G,A348S,T478R,P521S]-[G252V,T478K] AA.4 85 71 83.5% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AA.4 85 14 16.5% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.370 85 83 97.6% 0 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.370 85 2 2.4% 2 +[Q218R,S939F,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBJ 85 56 65.9% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) XBJ 85 6 7.1% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,S691F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ 85 3 3.5% 1 +[T73A,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ 85 2 2.4% 1 +[S151I,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ 85 2 2.4% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,H1058Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BQ.1.1.49 85 33 38.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,H1083D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.49 85 30 35.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F456L,F486V,H1083D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.49 85 4 4.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,H1083D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.49 85 3 3.5% 3 +[H69-,V70-,V213G,G339D,L452R,F456L,F486V,H1083D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,F486P,F490S] BQ.1.1.49 85 2 2.4% 1 +[H69-,V70-,V213G,Y248H,G339D,K444T,L452R,F486V,H1083D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.268 85 75 88.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.268 85 7 8.2% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.268 85 2 2.4% 1 +[F32L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.268 85 1 1.2% 1 +[F2L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.372 85 55 64.7% 0 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.372 85 25 29.4% 1 +[Q779L,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.372 85 2 2.4% 2 +[G413W,Q779L,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.372 85 2 2.4% 1 +[L54F,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.372 85 1 1.2% 1 +[V308L,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.41 85 53 62.4% 0 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.41 85 24 28.2% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V,A668S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.41 85 2 2.4% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V,L1063F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.41 85 1 1.2% 3 +[A27-,H69-,V70-,V213G,G339D,K444R,L452R,F486V,A668S]-[L24-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.41 85 1 1.2% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.6 84 76 90.5% 0 +[H146K,L216F,F486S]-[H146Q,F486P] (consensus) XBB.1.6 84 2 2.4% 1 +[H146K,L216F,F486S]-[H146Q,K417N,F486P] XBB.1.6 84 1 1.2% 2 +[H146K,L216F,F486S,S940F,G1099V]-[H146Q,F486P] XBB.1.6 84 1 1.2% 1 +[H146K,L216F,F486S,G891D]-[H146Q,F486P] XBB.1.6 84 1 1.2% 1 +[H146K,L216F,F486S]-[Y144-,H146Q,F486P] K.2 84 59 70.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] (consensus) K.2 84 9 10.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] K.2 84 3 3.6% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] K.2 84 2 2.4% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] K.2 84 2 2.4% 1 +[H66R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.618 84 37 44.0% 0 +[H146-,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.618 84 35 41.7% 1 +[H49Y,H146-,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.618 84 2 2.4% 2 +[H146-,A262S,E484K,N501H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.618 84 2 2.4% 4 +[E484K,S810L,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.618 84 2 2.4% 1 +[H146-,T299I,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.405 84 36 42.9% 0 +[E654K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.405 84 25 29.8% 1 +[L18F,E654K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.405 84 6 7.1% 1 +[A475V,E654K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.405 84 4 4.8% 1 +[T95I,E654K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.405 84 4 4.8% 1 +[E654K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] AY.127.2 84 44 52.4% 0 +[T19R,T95I,K113M,E156G,F157-,R158-,L452R,P681R,T859N,V860I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.127.2 84 15 17.9% 1 +[T19R,T95I,K113M,E156G,F157-,R158-,L452R,P681R,T859N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127.2 84 9 10.7% 2 +[T19R,H69Y,T95I,K113M,E156G,F157-,R158-,L452R,P681R,T859N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127.2 84 4 4.8% 1 +[T19R,T95I,K113M,E156G,F157-,R158-,L452R,P681R,A684V,T859N,V860I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127.2 84 3 3.6% 2 +[T19R,G75A,T95I,K113M,E156G,F157-,R158-,L452R,P681R,T859N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.2.1 84 72 85.7% 0 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.2.1 84 2 2.4% 1 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] JN.2.1 84 1 1.2% 1 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.1 84 1 1.2% 1 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1219C]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.1 84 1 1.2% 4 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.4.6 84 72 85.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.4.6 84 3 3.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.6 84 2 2.4% 1 +[T604I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.6 84 2 2.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.6 84 1 1.2% 1 +[E1144Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.526 84 56 66.7% 0 +[V1230L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.526 84 12 14.3% 1 +[E484K,V1230L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.526 84 2 2.4% 2 +[G184V,V1104I,V1230L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.526 84 2 2.4% 3 +[P26S,Q173H,W258S,V1230L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.526 84 1 1.2% 2 +[V382L,L1200F,V1230L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.12 84 80 95.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.12 84 2 2.4% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.12 84 1 1.2% 1 +[D1146E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.12 84 1 1.2% 1 +[P479S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FW.1.1 84 37 44.0% 0 +[N148T,K356T,R403K,F486S,A701V]-[F486P] (consensus) FW.1.1 84 34 40.5% 1 +[N148T,K356T,R403K,F486S,A684T,A701V]-[F486P] FW.1.1 84 1 1.2% 1 +[N148T,K356T,R403K,T478Q,F486S,A701V]-[T478K,F486P] FW.1.1 84 1 1.2% 1 +[H146K,N148T,K356T,R403K,F486S,A701V]-[H146Q,F486P] FW.1.1 84 1 1.2% 2 +[N148T,K356T,S373A,R403K,F486S,A684T,A701V]-[S373P,F486P] DJ.1.2 84 41 48.8% 0 +[H69-,V70-,L176F,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) DJ.1.2 84 26 31.0% 1 +[H69-,V70-,L176F,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DJ.1.2 84 5 6.0% 1 +[H69-,V70-,L176F,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DJ.1.2 84 4 4.8% 2 +[H69-,V70-,L176F,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DJ.1.2 84 3 3.6% 2 +[H69-,V70-,L176F,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,K417N,V445P,G446S,F486P,F490S] B.1.589 83 70 84.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.589 83 4 4.8% 1 +[P26S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.589 83 2 2.4% 1 +[A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.589 83 1 1.2% 1 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.589 83 1 1.2% 1 +[P809L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.636 83 65 78.3% 0 +[L18F,N148T,A688V,G769R,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.636 83 10 12.0% 1 +[L18F,N148T,A688V,G769R,Q804H,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.636 83 2 2.4% 1 +[L5F,L18F,N148T,A688V,G769R,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.636 83 1 1.2% 2 +[L18F,N148T,T167S,T572I,A688V,G769R,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.636 83 1 1.2% 2 +[N148T,A688V,G769R,Q804H,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XY 83 76 91.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XY 83 2 2.4% 1 +[V213G,G339D,Q493R,E1262D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XY 83 2 2.4% 1 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XY 83 1 1.2% 2 +[V213G,G339Y,K444N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XY 83 1 1.2% 3 +[V213G,G339D,R346K,S371L,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,V445P,G446S,N460K,F486P,F490S] AY.26.1 83 60 72.3% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,E484Q,P681R,D950N,T1009S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.26.1 83 13 15.7% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,E484Q,P681R,D950N,T1009S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.26.1 83 3 3.6% 1 +[T19R,E156G,F157-,R158-,A222V,K444N,L452R,E484Q,P681R,D950N,T1009S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.26.1 83 2 2.4% 2 +[T19R,G75V,T76I,E156G,F157-,R158-,A222V,L452R,E484Q,P681R,D950N,T1009S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.26.1 83 1 1.2% 1 +[T19R,D138Y,E156G,F157-,R158-,A222V,L452R,E484Q,P681R,D950N,T1009S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.24 83 50 60.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.24 83 13 15.7% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.24 83 3 3.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] JN.1.24 83 2 2.4% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V687A,A845V,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.24 83 1 1.2% 2 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,W152L,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] L.2 83 47 56.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) L.2 83 34 41.0% 1 +[V70F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.2 83 1 1.2% 2 +[H49Y,V70F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.2 83 1 1.2% 2 +[G35V,V70F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HQ.1 83 44 53.0% 0 +[E554K] (consensus) HQ.1 83 10 12.0% 1 +[E554K]-[R408S] HQ.1 83 8 9.6% 1 +[E554K,T747I] HQ.1 83 2 2.4% 2 +[S254F,E554K,R683L] HQ.1 83 2 2.4% 2 +[S494P,E554K]-[R408S] JM.1 83 61 73.5% 0 +[Q52H,K147N,E180V,T478R,P521S]-[T478K] (consensus) JM.1 83 3 3.6% 1 +[Q52H,K147N,E180V,T478R,P521S,Q675R]-[T478K] JM.1 83 3 3.6% 1 +[Q52H,K147N,E180V,T478R,P521S,A653V]-[T478K] JM.1 83 2 2.4% 3 +[Q52H,K147N,E180V,+374F,T376-,T478R,P521S]-[S375F,T376A,T478K] JM.1 83 2 2.4% 1 +[Q52H,K147N,E180V,T478R,P521S,E702V]-[T478K] XBB.1.24.3 83 45 54.2% 0 +[S256L] (consensus) XBB.1.24.3 83 7 8.4% 1 +[N148T,S256L] XBB.1.24.3 83 6 7.2% 1 +[D80G,S256L] XBB.1.24.3 83 6 7.2% 1 +[S256L]-[K417N] XBB.1.24.3 83 2 2.4% 1 +[S256L,G1124V] XBB.1.9.5 83 21 25.3% 0 +[F486S]-[F486P] (consensus) XBB.1.9.5 83 12 14.5% 1 +[F486S,E619K]-[F486P] XBB.1.9.5 83 11 13.3% 2 +[F486S,P521T,A1070V]-[F486P] XBB.1.9.5 83 6 7.2% 1 +[F486S,T1006A]-[F486P] XBB.1.9.5 83 5 6.0% 2 +[E619K] FD.1 83 66 79.5% 0 (consensus) FD.1 83 6 7.2% 1 +[L8F] FD.1 83 3 3.6% 1 +[L242F] FD.1 83 2 2.4% 1 +[P521S] FD.1 83 1 1.2% 2 +[L5F,H69Y] CK.1.2 82 51 62.2% 0 +[H69-,V70-,G181V,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1.2 82 16 19.5% 1 +[H69-,V70-,G181V,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CK.1.2 82 3 3.7% 1 +[H69-,V70-,G181V,V213G,S256L,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CK.1.2 82 2 2.4% 2 +[H69-,V70-,G181V,V213G,G339D,K444N,L452R,F486V,A942S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CK.1.2 82 2 2.4% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] B.1.632 82 66 80.5% 0 +[T29I,F32L,M153T,F157S,E484K,D936H,D1260H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.632 82 3 3.7% 1 +[T29I,F32L,M153T,F157S,E484K,D936H,Q1071L,D1260H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,N764K,D796Y,Q954H,N969K] B.1.632 82 2 2.4% 1 +[T29I,F32L,M153T,F157S,E484K,D936H,L1063F,D1260H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,N764K,D796Y,Q954H,N969K] B.1.632 82 2 2.4% 1 +[T29I,F32L,M153T,F157S,D215Y,E484K,D936H,D1260H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,N764K,D796Y,Q954H,N969K] B.1.632 82 1 1.2% 1 +[T29I,F32L,M153T,F157S,R246I,E484K,D936H,D1260H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,N764K,D796Y,Q954H,N969K] B.1.1.158 82 72 87.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.158 82 6 7.3% 1 +[D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.158 82 2 2.4% 1 +[A845V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.158 82 1 1.2% 2 +[D1139N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.158 82 1 1.2% 1 +[E554Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.237 82 45 54.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.237 82 10 12.2% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.237 82 5 6.1% 1 +[Q14H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.237 82 4 4.9% 2 +[A222V,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.237 82 3 3.7% 1 +[P384S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.356 82 57 69.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.356 82 11 13.4% 1 +[P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.356 82 11 13.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.356 82 1 1.2% 1 +[S1021F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.356 82 1 1.2% 1 +[S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.7 82 78 95.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AA.7 82 3 3.7% 1 +[A222V,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.7 82 1 1.2% 1 +[A222V,T1009I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BL.4 82 33 40.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BL.4 82 8 9.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.4 82 7 8.5% 1 +[S112A,K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BL.4 82 6 7.3% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BL.4 82 4 4.9% 2 +[K147E,W152R,F157L,I210V,V213G,P251T,G257S,D574V,I909V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.5.2.42 82 70 85.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L981I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.42 82 6 7.3% 1 +[H69-,V70-,V213G,A263S,G339D,K444T,L452R,F486V,L981I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.42 82 1 1.2% 2 +[W64R,H69-,V70-,V213G,G268S,G339D,K444T,L452R,F486V,L981I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.42 82 1 1.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L981I,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.42 82 1 1.2% 1 +[H69-,V70-,G75V,V213G,G339D,K444T,L452R,F486V,L981I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] HA.1 82 53 64.6% 0 +[F456L] (consensus) HA.1 82 7 8.5% 1 +[H146K,F456L]-[H146Q] HA.1 82 6 7.3% 1 +[F456L,E554K] HA.1 82 4 4.9% 1 +[F456L]-[V83A] HA.1 82 1 1.2% 2 +[F456L]-[V83A,Y505H] XBB.1.5.85 82 49 59.8% 0 +[L176F,T478R]-[T478K] (consensus) XBB.1.5.85 82 5 6.1% 1 +[L176F,T478R,S689I]-[T478K] XBB.1.5.85 82 5 6.1% 1 +[L176F,T478R,K535T]-[T478K] XBB.1.5.85 82 4 4.9% 1 +[L176F,T478R,P621S]-[T478K] XBB.1.5.85 82 2 2.4% 1 +[L176F,T478R,P809L]-[T478K] B.1.1.300 82 82 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.45.1 82 53 64.6% 0 (consensus) XBB.1.45.1 82 6 7.3% 1 +[L368V]-[L368I] XBB.1.45.1 82 4 4.9% 1 +[T747I] XBB.1.45.1 82 2 2.4% 2 +[T747I,I834V] XBB.1.45.1 82 2 2.4% 1 +[H146K]-[H146Q] B.1.570 81 50 61.7% 0 +[P681L,T1120S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.570 81 10 12.3% 1 +[P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.570 81 6 7.4% 1 +[T51I,P681L,T1120S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.570 81 5 6.2% 2 +[P681L,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.570 81 3 3.7% 1 +[A163V,P681L,T1120S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.36 81 41 50.6% 0 +[R190S,K356T,T572I,A899S,A1070T] (consensus) FL.36 81 11 13.6% 1 +[T76I,R190S,K356T,T572I,A899S,A1070T] FL.36 81 9 11.1% 1 +[R190S,K356T,T572I,Q675H,A899S,A1070T] FL.36 81 4 4.9% 2 +[R190S,K356T,T572I,Q675H,S691F,A899S,A1070T] FL.36 81 2 2.5% 1 +[R190S,K356T,P479L,T572I,A899S,A1070T] B.1.406 81 67 82.7% 0 +[D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.406 81 4 4.9% 1 +[V622F,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.406 81 4 4.9% 1 +[A701S,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.406 81 2 2.5% 1 +[D1139N,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.406 81 2 2.5% 1 +[V171A,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.53 81 67 82.7% 0 +[Y28H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.53 81 12 14.8% 1 +[Y28H,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.53 81 1 1.2% 1 +[Y28H,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.53 81 1 1.2% 1 +[Y28H,L560M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.118 81 72 88.9% 0 +[S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.118 81 2 2.5% 1 +[T95I,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.118 81 1 1.2% 1 +[S640F,S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.118 81 1 1.2% 1 +[S640F,Q677R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.118 81 1 1.2% 1 +[S640F,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BL.1.5 81 74 91.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,A475V,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BL.1.5 81 1 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,A475V,K558N,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.1.5 81 1 1.2% 4 +[I210V,V213G,G257S,A475V,D574V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.1.5 81 1 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,A475V,T523N,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.1.5 81 1 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,A243S,G257S,A475V,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EG.2.3 81 63 77.8% 0 +[T478R,I742V]-[T478K] (consensus) EG.2.3 81 5 6.2% 1 +[H245N,T478R,I742V]-[T478K] EG.2.3 81 4 4.9% 1 +[P251S,T478R,I742V]-[T478K] EG.2.3 81 2 2.5% 1 +[T478R,A623V,I742V]-[T478K] EG.2.3 81 1 1.2% 1 +[A67V,T478R,I742V]-[T478K] P.1.10.1 81 63 77.8% 0 +[L18F,T20N,P26S,H69-,V70-,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.10.1 81 10 12.3% 2 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10.1 81 5 6.2% 3 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,D1165Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10.1 81 1 1.2% 2 +[L18F,T20N,P26S,H69-,V70-,D138Y,K417T,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10.1 81 1 1.2% 1 +[L18F,T20N,P26S,N30H,H69-,V70-,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.540 80 41 51.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.540 80 7 8.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.540 80 7 8.8% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.540 80 5 6.2% 1 +[E554D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.540 80 2 2.5% 2 +[T29I,E554D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FA.1 80 70 87.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] (consensus) FA.1 80 4 5.0% 1 +[H69-,V70-,I197V,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] FA.1 80 2 2.5% 1 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] FA.1 80 1 1.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,T478K,F486P,F490S] FA.1 80 1 1.2% 2 +[H69-,V70-,T76I,V213G,G339D,K444T,L452R,T478R,F486V,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] FK.1.2 80 58 72.5% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.2 80 6 7.5% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,N460K,F486P,F490S] FK.1.2 80 5 6.2% 1 +[K147E,W152R,F157L,G184V,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.2 80 3 3.8% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.2 80 2 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DS.3 80 70 87.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) DS.3 80 2 2.5% 2 +[H69-,V70-,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] DS.3 80 1 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E583Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] DS.3 80 1 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,A222V,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] DS.3 80 1 1.2% 1 +[K147E,W152R,F157L,K182E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] JN.1.10 80 44 55.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.10 80 5 6.2% 2 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.10 80 5 6.2% 4 +[R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.10 80 2 2.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.10 80 2 2.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] CQ.1.1 80 69 86.2% 0 +[H69-,V70-,P209L,V213G,A262S,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CQ.1.1 80 2 2.5% 1 +[H69-,V70-,P209L,V213G,A262S,G339D,K444R,L452R,F486V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CQ.1.1 80 1 1.2% 1 +[H69-,V70-,P209L,V213G,A262S,G339D,K444R,L452R,F486V,H1083Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CQ.1.1 80 1 1.2% 5 +[T29I,H69-,V70-,F157S,P209L,V213G,G257D,A262S,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P] CQ.1.1 80 1 1.2% 1 +[H69-,V70-,P209L,V213G,A262S,G339D,K444R,L452R,A475S,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.437 80 52 65.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.437 80 23 28.8% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.437 80 2 2.5% 1 +[S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.437 80 1 1.2% 1 +[H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.437 80 1 1.2% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.3.9 80 44 55.0% 0 +[S98F,D253G,P521S]-[G252V] (consensus) XBB.2.3.9 80 9 11.2% 2 +[S98F,H146K,L216F,D253G,P521S]-[H146Q,G252V] XBB.2.3.9 80 8 10.0% 1 +[S98F,L216F,D253G,P521S]-[G252V] XBB.2.3.9 80 7 8.8% 1 +[S98F,D253G,T478R,P521S]-[G252V,T478K] XBB.2.3.9 80 2 2.5% 2 +[S98F,D253G,P521S,T768I,T961M]-[G252V] B.1.1.29 80 61 76.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.29 80 10 12.5% 2 +[E484Q,Q779H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.29 80 6 7.5% 1 +[Q779H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.29 80 1 1.2% 3 +[E484Q,D574Y,Q779H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.29 80 1 1.2% 1 +[P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.61 79 74 93.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.61 79 3 3.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.61 79 1 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621H,V1040F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.61 79 1 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P621H,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XAA 79 47 59.5% 0 +[V213G,G339D,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAA 79 28 35.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAA 79 2 2.5% 2 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAA 79 1 1.3% 1 +[F157L,V213G,G339D,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAA 79 1 1.3% 3 +[V213G,G339D,Q493R,V642F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.1.353 79 33 41.8% 0 +[F186S,D215H,T323I,A1078T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.353 79 28 35.4% 3 +[A1078T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.353 79 6 7.6% 4 +[A262S,A1078T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.353 79 2 2.5% 5 +[T95I,A262S,A1078T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.353 79 2 2.5% 4 +[I844V,A1078T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CM.8.1.4 79 42 53.2% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] (consensus) CM.8.1.4 79 6 7.6% 2 +[V70F,K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.4 79 6 7.6% 1 +[K147N,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.4 79 5 6.3% 2 +[K97E,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,Q677R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.4 79 2 2.5% 2 +[M153T,N164K,N211-,L212I,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] B.1.357 79 68 86.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.357 79 6 7.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.357 79 3 3.8% 1 +[A93S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.357 79 1 1.3% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.357 79 1 1.3% 2 +[L5F,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.267 79 73 92.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.267 79 2 2.5% 1 +[R346K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.267 79 1 1.3% 1 +[A27T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.267 79 1 1.3% 1 +[V213L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.267 79 1 1.3% 4 +[L141-,G142-,V143-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.221 79 75 94.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.221 79 2 2.5% 1 +[N603I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.221 79 1 1.3% 1 +[T299I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.221 79 1 1.3% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EN.1.1 79 54 68.4% 0 +[H69-,V70-,M153I,F157L,V213G,G339D,K444T,L452R,F486V,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EN.1.1 79 6 7.6% 1 +[H69-,V70-,M153I,F157L,V213G,G339D,K444T,L452R,F486V,A845G,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EN.1.1 79 6 7.6% 2 +[H69-,V70-,M153I,F157L,V213G,G339D,K444T,L452R,G482R,F486V,A845G,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EN.1.1 79 4 5.1% 1 +[H69-,V70-,M153I,F157L,V213G,G339D,K444T,L452R,F486V,A701V,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EN.1.1 79 2 2.5% 2 +[H69-,V70-,M153I,F157L,V213G,G339D,K444T,L452R,G482S,F486V,A845G,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FL.19.1 79 44 55.7% 0 +[F456L] (consensus) FL.19.1 79 17 21.5% 1 +[F456L,Q677R] FL.19.1 79 4 5.1% 1 +[L5F,F456L] FL.19.1 79 2 2.5% 1 +[L176F,F456L] FL.19.1 79 2 2.5% 2 +[F456L,E619V,Q677R] HK.4 79 50 63.3% 0 +[Q52H,F456L,T883I] (consensus) HK.4 79 6 7.6% 1 +[Q52H,F456L,T883I,P1162S] HK.4 79 3 3.8% 1 +[Q52H,H146K,F456L,T883I]-[H146Q] HK.4 79 3 3.8% 1 +[L5F,Q52H,F456L,T883I] HK.4 79 2 2.5% 3 +[Q52H,L176F,F456L,T883I,S929T,P1162S] B.1.438 78 41 52.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.438 78 13 16.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438 78 12 15.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438 78 4 5.1% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438 78 1 1.3% 2 +[R214H,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.54 78 47 60.3% 0 (consensus) XBB.1.5.54 78 4 5.1% 1 +[M1237I] XBB.1.5.54 78 4 5.1% 1 +[T478R]-[T478K] XBB.1.5.54 78 2 2.6% 1 +[A263E] XBB.1.5.54 78 2 2.6% 2 +[T478R,S968F]-[T478K] AY.20.1 78 43 55.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.20.1 78 8 10.3% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.20.1 78 6 7.7% 2 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.20.1 78 5 6.4% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.20.1 78 3 3.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.3.11 78 21 26.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.11 78 20 25.6% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q675K,V1104L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.11 78 20 25.6% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,G261V,K356T,Q675K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.11 78 5 6.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q675K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.11 78 4 5.1% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,G485S,Q675K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBB.1.5.105 78 58 74.4% 0 +[K304N] (consensus) XBB.1.5.105 78 6 7.7% 1 +[H245Y,K304N] XBB.1.5.105 78 5 6.4% 1 +[H146K,K304N]-[H146Q] XBB.1.5.105 78 2 2.6% 1 +[K304N,E554D] XBB.1.5.105 78 2 2.6% 1 +[A67V,K304N] BF.7.16.1 78 53 67.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.16.1 78 17 21.8% 1 +[H69-,V70-,G75A,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.16.1 78 2 2.6% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.16.1 78 1 1.3% 1 +[F59S,H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.16.1 78 1 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V,Q755H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.11.1 77 69 89.6% 0 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.11.1 77 3 3.9% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.11.1 77 2 2.6% 1 +[L5F,H69-,V70-,N185D,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.11.1 77 1 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,T604I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.11.1 77 1 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,A411S,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XDP.1 77 50 64.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDP.1 77 8 10.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDP.1 77 6 7.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDP.1 77 2 2.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDP.1 77 1 1.3% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092D,V1104L,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.402 77 54 70.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.402 77 10 13.0% 2 +[P1162L,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.402 77 4 5.2% 1 +[S940A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.402 77 1 1.3% 1 +[V483F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.402 77 1 1.3% 1 +[S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.325 77 64 83.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.325 77 3 3.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.325 77 1 1.3% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.325 77 1 1.3% 1 +[T696A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.325 77 1 1.3% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.229 77 59 76.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.229 77 5 6.5% 5 +[L5F,T323I,E484K,T716I,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.229 77 4 5.2% 4 +[T323I,E484K,T716I,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.229 77 3 3.9% 3 +[P26R,T240I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.229 77 2 2.6% 1 +[S477I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HE.1 77 57 74.0% 0 +[F456L,V622I] (consensus) HE.1 77 7 9.1% 1 +[V227L,F456L,V622I] HE.1 77 5 6.5% 2 +[V227L,F456L,V622I,D1153Y] HE.1 77 2 2.6% 1 +[H146K,F456L,V622I]-[H146Q] HE.1 77 2 2.6% 2 +[D138N,V227L,F456L,V622I] XAQ 77 74 96.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAQ 77 2 2.6% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAQ 77 1 1.3% 1 +[V213G,G339D,Q493R,N1192D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] KW.1.1 76 60 78.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KW.1.1 76 3 3.9% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KW.1.1 76 3 3.9% 2 +[+16MPLF,R21T,S50L,H69-,V70-,T95S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KW.1.1 76 2 2.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,L1200F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KW.1.1 76 1 1.3% 5 +[R21T,N30H,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47.1 76 61 80.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.47.1 76 3 3.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47.1 76 2 2.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47.1 76 1 1.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47.1 76 1 1.3% 1 +[V6A,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.23 76 33 43.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.23 76 8 10.5% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N137K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.23 76 4 5.3% 6 +[R21T,S50L,H69-,V70-,V127F,N137K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.23 76 3 3.9% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.23 76 2 2.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445H,N450D,L452W,Y453F,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] DS.1 76 63 82.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,R403K,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) DS.1 76 2 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,R403K,F486S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] DS.1 76 2 2.6% 2 +[W64R,K147E,W152R,F157L,I210V,V213G,G257S,K356T,R403K,F486S,D1163A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] DS.1 76 1 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,R214L,G257S,K356T,R403K,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] DS.1 76 1 1.3% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K356T,R403K,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.222 76 61 80.3% 0 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.222 76 1 1.3% 1 +[N439K,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.222 76 1 1.3% 1 +[L84I,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.222 76 1 1.3% 1 +[N439K,H1159L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.222 76 1 1.3% 1 +[N439K,P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.335 75 71 94.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.335 75 1 1.3% 2 +[+520A,+521P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.335 75 1 1.3% 1 +[C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.335 75 1 1.3% 1 +[Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.335 75 1 1.3% 1 +[S12F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.6 75 52 69.3% 0 (consensus) EG.6 75 3 4.0% 1 -[R408S] EG.6 75 2 2.7% 1 +[E554K] EG.6 75 2 2.7% 1 +[I203V] EG.6 75 2 2.7% 2 -[R408S,K417N] B.1.177.71 75 61 81.3% 0 +[A222V,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.71 75 8 10.7% 1 +[L8F,A222V,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.71 75 5 6.7% 1 +[M153I,A222V,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.71 75 1 1.3% 1 +[S12F,A222V,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.12 75 75 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.571 75 59 78.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.571 75 4 5.3% 1 +[V367L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.571 75 3 4.0% 1 +[P251S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.571 75 2 2.7% 1 +[S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.571 75 2 2.7% 1 +[A27T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBL.3.1 75 59 78.7% 0 +[I726V] (consensus) XBL.3.1 75 4 5.3% 1 +[I726V]-[K417N] XBL.3.1 75 1 1.3% 1 +[L5F,I726V] XBL.3.1 75 1 1.3% 1 +[H146K,I726V]-[H146Q] XBL.3.1 75 1 1.3% 1 +[I726V]-[T19I] BA.4.1.7 75 70 93.3% 0 +[V3G,Q52R,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.7 75 2 2.7% 1 +[V3G,Q52R,H69-,V70-,V213G,G339D,L452R,F486V,P809S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.7 75 1 1.3% 1 +[V3G,Q52R,H69-,V70-,I100T,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.7 75 1 1.3% 1 +[V3G,Q52R,H69-,V70-,V213G,G339D,L452R,F486V,K1255R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.7 75 1 1.3% 1 +[V3G,Q52R,H69-,V70-,V213G,G339D,L452R,F486V,V1164F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.38.4 75 53 70.7% 0 +[K147E,V213G,G339D,K417T,K444N,Q493R,I692L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.38.4 75 3 4.0% 1 +[K147E,V213G,G339D,K417T,K444N,Q493R,I692L]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38.4 75 3 4.0% 1 +[K147E,V213G,G339D,K444N,Q493R,I692L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.38.4 75 2 2.7% 1 +[L5F,K147E,V213G,G339D,K417T,K444N,Q493R,I692L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38.4 75 2 2.7% 2 +[K147E,V213G,G339D,Q493R,I692L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.403 75 65 86.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.403 75 2 2.7% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.403 75 1 1.3% 1 +[A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.403 75 1 1.3% 1 +[D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.403 75 1 1.3% 2 +[T29I,S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.395 75 63 84.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.395 75 4 5.3% 1 +[D1257E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.395 75 2 2.7% 2 +[T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.395 75 1 1.3% 3 +[H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.395 75 1 1.3% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.4.10 75 54 72.0% 0 +[V1129I] (consensus) FL.4.10 75 3 4.0% 1 +[V483F,V1129I] FL.4.10 75 3 4.0% 1 +[F157L,V1129I] FL.4.10 75 2 2.7% 1 +[V1129I,D1146H] FL.4.10 75 1 1.3% 1 +[P330S,V1129I] B.10 75 55 73.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.10 75 4 5.3% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.10 75 2 2.7% 2 +[D936H,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.10 75 2 2.7% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.10 75 1 1.3% 3 +[T95I,N185K,R685S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BY.1.2 75 66 88.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BY.1.2 75 2 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.2 75 2 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,T1273A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.2 75 1 1.3% 1 +[V70I,K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.2 75 1 1.3% 1 +[K147E,W152Q,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.260 74 49 66.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.260 74 23 31.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.260 74 1 1.4% 1 +[S205F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.260 74 1 1.4% 1 +[S691F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.333 74 62 83.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.333 74 1 1.4% 1 +[S297L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.333 74 1 1.4% 5 +[V6F,T95I,C361T,Y505W,Q506K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.333 74 1 1.4% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.333 74 1 1.4% 5 +[F79V,Q183P,Y505W,Q506K,M902L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.518 74 72 97.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.518 74 1 1.4% 1 +[S50L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.518 74 1 1.4% 1 +[D1139Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.76.2 74 71 95.9% 0 +[N185H,V213G,Y248N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.76.2 74 2 2.7% 1 +[N185H,V213G,Y248N,G339D,Q493R,L1203F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.76.2 74 1 1.4% 1 +[N185H,V213G,Y248N,G339D,Q493R,V963I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] C.38 74 30 40.5% 0 +[P9L,W64R,D138-,P139-,F140-,L141-,G142-,V143-,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] (consensus) C.38 74 13 17.6% 1 +[P9L,W64R,D138-,P139-,F140-,L141-,G142-,V143-,E484K,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] C.38 74 4 5.4% 11 +[W64R,D138Y,E484K,C1241S,C1243S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.38 74 3 4.1% 2 +[P9L,W64R,D138-,P139-,F140-,L141-,G142-,V143-,S254F,E484K,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] C.38 74 3 4.1% 10 +[P9L,E484K,P1263Q,V1264M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.1.266 74 48 64.9% 0 +[L5F,S459Y,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.266 74 7 9.5% 3 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.266 74 5 6.8% 1 +[L5F,S459Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.266 74 5 6.8% 2 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.266 74 3 4.1% 4 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.1.2 74 43 58.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.1.2 74 8 10.8% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.2 74 8 10.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.2 74 1 1.4% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.1.2 74 1 1.4% 6 +[N17M,R21T,S50L,H69-,V70-,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1199N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.36.1 74 44 59.5% 0 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.36.1 74 15 20.3% 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.36.1 74 2 2.7% 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.36.1 74 2 2.7% 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.36.1 74 1 1.4% 5 +[P9T,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] FE.1.1.4 74 56 75.7% 0 +[F456L] (consensus) FE.1.1.4 74 6 8.1% 1 +[S98F,F456L] FE.1.1.4 74 3 4.1% 1 +[F456L]-[R346T] FE.1.1.4 74 2 2.7% 2 +[F456L]-[R346T,K417N] FE.1.1.4 74 1 1.4% 1 +[F456L]-[K417N] GJ.5.1 74 45 60.8% 0 +[K182N,D253G,S255F,T478R,P521S]-[G252V,T478K] (consensus) GJ.5.1 74 3 4.1% 1 +[D53E,K182N,D253G,S255F,T478R,P521S]-[G252V,T478K] GJ.5.1 74 2 2.7% 1 +[K182N,D253G,S255F,T478R,P521S]-[T19I,G252V,T478K] GJ.5.1 74 1 1.4% 1 +[L18F,K182N,D253G,S255F,T478R,P521S]-[G252V,T478K] GJ.5.1 74 1 1.4% 1 +[K182N,H245R,D253G,S255F,T478R,P521S]-[G252V,T478K] B.1.586 74 69 93.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.586 74 2 2.7% 1 +[A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.586 74 1 1.4% 1 +[S221L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.586 74 1 1.4% 1 +[N709D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.586 74 1 1.4% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.461 73 64 87.7% 0 +[Q675R,A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.461 73 5 6.8% 1 +[Q675R,A879S,T1027S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.461 73 1 1.4% 2 +[P251L,Q675R,A879S,T1027S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.461 73 1 1.4% 2 +[P631S,Q675R,A879S,T1027S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.461 73 1 1.4% 2 +[S45P,Q675R,A879S,T1009I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.46 73 53 72.6% 0 +[F486S]-[F486P] (consensus) XBB.1.46 73 7 9.6% 2 +[T478Q]-[T478K] XBB.1.46 73 2 2.7% 1 +[H146K,F486S]-[H146Q,F486P] XBB.1.46 73 2 2.7% 2 +[L244F,H245-,F486S]-[F486P] XBB.1.46 73 2 2.7% 3 +[T478Q]-[Y144-,T478K] B.1.117 73 69 94.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.117 73 4 5.5% 1 +[M731I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBH 73 61 83.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) XBH 73 2 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBH 73 1 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,T250I,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBH 73 1 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,A688V,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBH 73 1 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,R1014K,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.5.2.38 73 54 74.0% 0 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.38 73 5 6.8% 1 +[H69-,V70-,G181V,V213G,G339D,T430I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.38 73 5 6.8% 1 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V,A871V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.38 73 2 2.7% 1 +[H69-,V70-,L212S,V213G,G339D,T430I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.38 73 2 2.7% 1 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.534 73 64 87.7% 0 +[T859I,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.534 73 6 8.2% 1 +[L5F,T859I,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.534 73 2 2.7% 1 +[R765L,T859I,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.534 73 1 1.4% 1 +[P9S,T859I,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.308 73 66 90.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.308 73 3 4.1% 1 +[V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.308 73 1 1.4% 1 +[H245Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.308 73 1 1.4% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.308 73 1 1.4% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.6 73 38 52.1% 0 +[H146K]-[H146Q] (consensus) FL.6 73 4 5.5% 1 FL.6 73 4 5.5% 2 +[A348S] FL.6 73 4 5.5% 2 -[R408S] FL.6 73 4 5.5% 2 -[K417N] BN.2 73 52 71.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BN.2 73 9 12.3% 1 +[K147E,W152R,F157L,I210V,L212S,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BN.2 73 4 5.5% 2 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BN.2 73 1 1.4% 2 +[K147E,W152R,F157L,G181A,I210V,V213G,G257S,K356T,T478E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,F486P,F490S] BN.2 73 1 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T478E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,F486P,F490S] B.1.293 72 57 79.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.293 72 4 5.6% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.293 72 2 2.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.293 72 1 1.4% 1 +[A684V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.293 72 1 1.4% 1 +[V143A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.507 72 60 83.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.507 72 3 4.2% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.507 72 2 2.8% 1 +[S813I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.507 72 2 2.8% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.507 72 2 2.8% 2 +[V267L,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.159 72 62 86.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.159 72 2 2.8% 1 +[P26L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.159 72 2 2.8% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.159 72 1 1.4% 1 +[P1112Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.159 72 1 1.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.8 72 52 72.2% 0 (consensus) EG.8 72 4 5.6% 1 +[F1103L] EG.8 72 2 2.8% 2 +[K356T,T638I] EG.8 72 2 2.8% 1 +[S1003I] EG.8 72 1 1.4% 1 +[A575S] XAU 72 65 90.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAU 72 1 1.4% 2 +[V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAU 72 1 1.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAU 72 1 1.4% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAU 72 1 1.4% 1 +[V213G,A243S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBC.1.5 72 21 29.2% 0 +[P25S,E156G,F157-,R158-,V171I,P209L,L212S,D215H,A222V,A243-,L244-,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.5 72 17 23.6% 2 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.5 72 17 23.6% 1 +[P25S,E156G,F157-,R158-,V171I,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.5 72 2 2.8% 3 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,E406Q,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.5 72 2 2.8% 4 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N536D,E554A,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] B.1.274 72 71 98.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.274 72 1 1.4% 1 +[Q14H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FZ.2 72 62 86.1% 0 +[Q836R] (consensus) FZ.2 72 1 1.4% 2 +[P621S,Q836R,S1252F] FZ.2 72 1 1.4% 1 +[Q836R]-[K417N] FZ.2 72 1 1.4% 1 +[S494P,Q836R] FZ.2 72 1 1.4% 1 +[Q836R]-[V445P] XBB.1.9.4 71 55 77.5% 0 +[F486S]-[F486P] (consensus) XBB.1.9.4 71 2 2.8% 2 +[F486S,P521Q,Q853R]-[F486P] XBB.1.9.4 71 2 2.8% 1 +[F486S]-[K417N,F486P] XBB.1.9.4 71 1 1.4% 1 +[F192L,F486S]-[F486P] XBB.1.9.4 71 1 1.4% 1 +[F486S,T732I]-[F486P] GB.2 71 37 52.1% 0 +[T478R]-[T478K] (consensus) GB.2 71 12 16.9% 1 +[H146K,T478R]-[H146Q,T478K] GB.2 71 6 8.5% 1 +[T478R,T1117I]-[T478K] GB.2 71 2 2.8% 1 +[L293F,T478R]-[T478K] GB.2 71 1 1.4% 3 +[H146K,T478R,G1124V]-[Y144-,H146Q,T478K] XP 71 69 97.2% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) XP 71 1 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,S151R,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XP 71 1 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,T250I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.1.440 70 63 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.440 70 4 5.7% 2 +[V308L,V826L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.440 70 1 1.4% 1 +[L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.440 70 1 1.4% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.440 70 1 1.4% 2 +[D215H,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.131 70 30 42.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.131 70 23 32.9% 1 +[M177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.131 70 5 7.1% 1 +[N164S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.131 70 3 4.3% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.131 70 2 2.9% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAB 70 51 72.9% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAB 70 4 5.7% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAB 70 3 4.3% 1 +[V213G,G339D,Q493R,L1203F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAB 70 3 4.3% 2 +[V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAB 70 2 2.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] GJ.1.2.8 70 45 64.3% 0 +[K182N,D253G,P521S,T747I]-[G252V] (consensus) GJ.1.2.8 70 10 14.3% 1 +[K182N,D253G,P521S,T747I,P812S]-[G252V] GJ.1.2.8 70 4 5.7% 1 +[K182N,D253G,T259K,P521S,T747I]-[G252V] GJ.1.2.8 70 2 2.9% 1 +[K182N,D253G,P521S,T747I,A1016T]-[G252V] GJ.1.2.8 70 1 1.4% 1 +[K182N,D253G,P521S,T747I]-[G252V,R408S] XBB.1.5.101 70 39 55.7% 0 (consensus) XBB.1.5.101 70 9 12.9% 2 +[F157L,S698L] XBB.1.5.101 70 3 4.3% 1 +[P39S] XBB.1.5.101 70 2 2.9% 3 +[D178H,+214SS] XBB.1.5.101 70 2 2.9% 3 +[H146K,D1146V,M1237T]-[H146Q] B.35 70 63 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.35 70 3 4.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.35 70 1 1.4% 1 +[L242I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.35 70 1 1.4% 1 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.35 70 1 1.4% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.58 70 50 71.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.58 70 12 17.1% 1 +[A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.58 70 5 7.1% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.58 70 1 1.4% 1 +[L1001F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.58 70 1 1.4% 4 +[A352S,P384L,A694V,I1179T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KP.1.1.1 70 58 82.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KP.1.1.1 70 2 2.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.1.1.1 70 2 2.9% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.1.1.1 70 1 1.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,G75A,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.1.1.1 70 1 1.4% 1 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] EG.3 70 39 55.7% 0 (consensus) EG.3 70 9 12.9% 1 +[D253Y] EG.3 70 9 12.9% 1 +[H146K]-[H146Q] EG.3 70 4 5.7% 2 +[H146K,H1058Y]-[H146Q] EG.3 70 3 4.3% 2 +[T22N,H146K]-[H146Q] B.1.1.270 70 64 91.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.270 70 5 7.1% 2 +[G184S,A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.270 70 1 1.4% 3 +[V90F,G184S,A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GG.1 69 33 47.8% 0 +[T478R,I666V]-[T478K] (consensus) GG.1 69 9 13.0% 1 +[T478R,I666V,Q755H]-[T478K] GG.1 69 3 4.3% 1 +[L5F,T478R,I666V]-[T478K] GG.1 69 3 4.3% 2 +[T478R,I666V,Q755H]-[R408S,T478K] GG.1 69 2 2.9% 2 +[G184V,T478R,I666V,Q755H]-[T478K] B.1.160.20 69 61 88.4% 0 +[D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.20 69 2 2.9% 1 +[Q1071S,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.20 69 1 1.4% 1 +[L922F,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.20 69 1 1.4% 1 +[V615F,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.20 69 1 1.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.6 69 46 66.7% 0 +[F486S]-[G252V,F486P] (consensus) XBB.6 69 2 2.9% 3 +[F486S,E554G,Q613H,A771S]-[G252V,F486P] XBB.6 69 2 2.9% 3 +[F486S]-[G252V,S373P,S375F,T376A,F486P] XBB.6 69 2 2.9% 1 +[F486S]-[G252V,K417N,F486P] XBB.6 69 1 1.4% 2 +[H69-,V70-,F486S]-[G252V,F486P] B.1.527 69 61 88.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.527 69 2 2.9% 1 +[P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.527 69 1 1.4% 1 +[C1236F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.527 69 1 1.4% 1 +[D111N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.527 69 1 1.4% 1 +[V1129I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.8 69 59 85.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6.8 69 8 11.6% 1 +[E96V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.8 69 1 1.4% 2 +[N679Y,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.8 69 1 1.4% 1 +[I434V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.37 69 64 92.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.37 69 1 1.4% 1 +[C1248R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.37 69 1 1.4% 1 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.37 69 1 1.4% 7 +[P139-,F140-,L141-,G142-,V143-,Y145-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.37 69 1 1.4% 1 +[E132D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.13 69 48 69.6% 0 +[H69-,V70-,V213G,G339D,L452R,T478R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,T478K,F486P,F490S] (consensus) BE.13 69 3 4.3% 2 +[L5F,H69-,V70-,V213G,G339D,L452R,T478R,F486V,A570V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BE.13 69 3 4.3% 1 +[H69-,V70-,V213G,G339D,L452R,T478R,F486V,T747I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BE.13 69 2 2.9% 1 +[H69-,V70-,V213G,H245Y,G339D,L452R,T478R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BE.13 69 2 2.9% 1 +[H69-,V70-,V213G,G339D,L452R,T478R,F486V,T747I,S875A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,T478K,F486P,F490S] B.1.1.257 69 66 95.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.257 69 3 4.3% 1 +[+266Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.2 69 66 95.7% 0 +[E484K,Q677H,T732S,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) R.2 69 1 1.4% 1 +[R237S,E484K,Q677H,T732S,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.2 69 1 1.4% 1 +[E484K,T549A,Q677H,T732S,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.2 69 1 1.4% 1 +[E484K,Q677H,T732S,D1084Y,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.581 69 59 85.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.581 69 5 7.2% 1 +[P26S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.581 69 2 2.9% 1 +[C1241F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.581 69 1 1.4% 2 +[G75R,N1135Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.581 69 1 1.4% 2 +[V143D,M177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DB.2 69 60 87.0% 0 +[H69-,V70-,V213G,A262S,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DB.2 69 4 5.8% 1 +[H69-,V70-,V213G,A262S,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DB.2 69 3 4.3% 1 +[H69-,V70-,V213G,A262S,G339D,T430I,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DB.2 69 1 1.4% 1 +[H69-,V70-,V213G,A262S,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] DB.2 69 1 1.4% 1 +[H69-,V70-,V213G,A262S,G339D,K444T,L452R,F486V,G1204R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.35 69 50 72.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.35 69 4 5.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,I100V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.35 69 3 4.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,T678I,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.35 69 3 4.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.35 69 2 2.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,T73I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] DT.1 69 62 89.9% 0 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DT.1 69 2 2.9% 1 +[H69-,V70-,R78K,M153I,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.1 69 2 2.9% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,S494P,G1219C]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.1 69 1 1.4% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,S494P,G1124S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.1 69 1 1.4% 1 +[W64R,H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBL.1 69 34 49.3% 0 +[V635I] (consensus) XBL.1 69 9 13.0% 2 +[H146K,V635I,E1144V]-[H146Q] XBL.1 69 4 5.8% 1 +[V16F,V635I] XBL.1 69 3 4.3% 1 XBL.1 69 2 2.9% 1 +[V635I,L754F] B.1.1.299 69 53 76.8% 0 +[T549A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.299 69 15 21.7% 1 +[T549A,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.299 69 1 1.4% 1 +[S254F,T549A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.254 68 57 83.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.254 68 2 2.9% 3 +[E96A,S247R,E484D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.254 68 2 2.9% 1 +[G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.254 68 1 1.5% 2 +[L18F,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.254 68 1 1.5% 1 +[P809L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.34 68 50 73.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.34 68 4 5.9% 1 +[S810L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.34 68 3 4.4% 2 +[N121T,L1244F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.34 68 3 4.4% 1 +[L1244F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.34 68 2 2.9% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.149 68 61 89.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.149 68 2 2.9% 1 +[P384S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.149 68 2 2.9% 1 +[K1205N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.149 68 1 1.5% 1 +[D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.149 68 1 1.5% 2 +[S71F,D1146H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CP.4 68 66 97.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,I770V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.4 68 1 1.5% 1 +[H69-,V70-,G339D,L452R,F486V,I770V]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.4 68 1 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G639S,I770V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.19 68 27 39.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P,N603S,D614S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,D614G] BQ.1.19 68 17 25.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P,N603S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.19 68 4 5.9% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,N481S,F486V,S494P,N603S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.19 68 3 4.4% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P,N603S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N679K] BQ.1.19 68 3 4.4% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P,N603S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.385 68 51 75.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.385 68 9 13.2% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.385 68 2 2.9% 1 +[P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.385 68 2 2.9% 1 +[Y145H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.385 68 1 1.5% 1 +[A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.622 68 63 92.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.622 68 3 4.4% 1 +[C1247F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.622 68 1 1.5% 1 +[C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.622 68 1 1.5% 1 +[V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.282 68 63 92.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.282 68 2 2.9% 1 +[E324Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.282 68 1 1.5% 1 +[V1177L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.282 68 1 1.5% 3 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.282 68 1 1.5% 1 +[I68T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.151 68 40 58.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.151 68 19 27.9% 1 +[R102I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.151 68 4 5.9% 2 +[R102I,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.151 68 2 2.9% 2 +[T95I,R102I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.151 68 1 1.5% 1 +[L216F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.572 68 52 76.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.572 68 7 10.3% 1 +[A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.572 68 2 2.9% 2 +[M153I,A1026S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.572 68 1 1.5% 1 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.572 68 1 1.5% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Y.1 68 25 36.8% 0 +[A222V,P1162R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) Y.1 68 24 35.3% 1 +[A222V,E324V,P1162R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Y.1 68 4 5.9% 1 +[A222V,A520S,P1162R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Y.1 68 3 4.4% 2 +[A222V,E324V,P1162R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Y.1 68 3 4.4% 1 +[E96D,A222V,P1162R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.308 68 44 64.7% 0 +[W152L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.308 68 18 26.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.308 68 3 4.4% 1 +[W152L,M177R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.308 68 1 1.5% 2 +[I418V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.308 68 1 1.5% 1 +[P26S,W152L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EK.4 68 38 55.9% 0 +[Q675K] (consensus) EK.4 68 16 23.5% 1 +[D427Y,Q675K] EK.4 68 2 2.9% 2 +[D427Y,Q675K]-[G142D] EK.4 68 2 2.9% 1 +[Q675K,S1249Y] EK.4 68 2 2.9% 2 +[D427Y] B.1.1.465 68 45 66.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.465 68 22 32.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.465 68 1 1.5% 1 +[D53E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.61 67 64 95.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.61 67 2 3.0% 1 +[F565L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.61 67 1 1.5% 1 +[A879V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.550 67 58 86.6% 0 +[D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.550 67 3 4.5% 1 +[D253G,R1107S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.550 67 2 3.0% 1 +[D253G,A706V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.550 67 1 1.5% 1 +[D253G,G932S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.550 67 1 1.5% 1 +[D253G,T1006I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.74 67 47 70.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.74 67 6 9.0% 1 +[A222V,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.74 67 4 6.0% 1 +[A222V,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.74 67 2 3.0% 1 +[A222V,A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.74 67 2 3.0% 1 +[A222V,P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.27 67 35 52.2% 0 +[S254Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.27 67 18 26.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.27 67 4 6.0% 1 +[S254Y,E1144Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.27 67 2 3.0% 2 +[S254Y,V915F,E1144Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.27 67 2 3.0% 3 +[A684V,P862S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.22.3 67 52 77.6% 0 (consensus) XBB.1.22.3 67 4 6.0% 1 +[M1229I] XBB.1.22.3 67 3 4.5% 1 +[T676I] XBB.1.22.3 67 2 3.0% 1 +[V70F] XBB.1.22.3 67 2 3.0% 1 +[F157L] B.30 67 61 91.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.30 67 3 4.5% 1 +[A475V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.30 67 1 1.5% 2 +[T573I,L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.30 67 1 1.5% 2 +[F140-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] B.30 67 1 1.5% 1 +[L922M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CD.1 67 57 85.1% 0 +[H69-,V70-,L84I,V213G,G339D,G446D,L452R,F486V,A688T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CD.1 67 4 6.0% 1 +[H69-,V70-,L84I,V213G,G339D,G446D,L452R,F486V,A688T]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CD.1 67 2 3.0% 1 +[H69-,V70-,L84I,V213G,G339D,G446D,L452R,F486V,A688T]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CD.1 67 1 1.5% 1 +[Y28N,H69-,V70-,L84I,V213G,G339D,G446D,L452R,F486V,A688T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CD.1 67 1 1.5% 1 +[H69-,V70-,L84I,V213G,G339D,G446D,L452R,F486V,A688T,P812S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.2.2 67 45 67.2% 0 +[D253G,F486S,Q613H]-[G252V,F486P] (consensus) XBB.2.2 67 7 10.4% 1 +[D253G,F486S,Q613H,V1122L]-[G252V,F486P] XBB.2.2 67 2 3.0% 2 +[L5F,D253G,F486S,Q613H,V1122L]-[G252V,F486P] XBB.2.2 67 1 1.5% 1 +[D253G,F486S,Q613H]-[G252V,R346T,F486P] XBB.2.2 67 1 1.5% 2 +[L5F,D253G,F486S,Q613H]-[G142D,G252V,F486P] BF.7.13 67 48 71.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.13 67 4 6.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.13 67 2 3.0% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.13 67 2 3.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1116N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.13 67 1 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] XAY.1 67 64 95.5% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.1 67 1 1.5% 2 +[L18F,T19R,R21G,H69-,V70-,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.1 67 1 1.5% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,V635I,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.1 67 1 1.5% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,A344V,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] B.1.1.125 67 65 97.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.125 67 1 1.5% 1 +[V143F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.125 67 1 1.5% 1 +[H1101N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GA.5 67 33 49.3% 0 +[D215H] (consensus) GA.5 67 19 28.4% 1 +[H146K,D215H]-[H146Q] GA.5 67 2 3.0% 1 +[D215H,A845V] GA.5 67 1 1.5% 2 +[H69-,V70-,D215H] GA.5 67 1 1.5% 1 +[D215H]-[V83A] LB.1 66 38 57.6% 0 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) LB.1 66 9 13.6% 4 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] LB.1 66 5 7.6% 1 +[+16MPLF,R21T,S31-,R34C,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] LB.1 66 2 3.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] LB.1 66 2 3.0% 1 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] AY.46.6.1 66 40 60.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.6.1 66 14 21.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.6.1 66 4 6.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A688V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.6.1 66 2 3.0% 3 +[T19R,V143-,Y145-,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.6.1 66 1 1.5% 2 +[L18F,T19R,E156G,F157-,R158-,L452R,P681R,A688V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAP 66 61 92.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAP 66 1 1.5% 1 +[V213G,G339D,Q493R,M731I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAP 66 1 1.5% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAP 66 1 1.5% 1 +[K97N,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAP 66 1 1.5% 1 +[V213G,G339D,Q493R,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] U.1 66 61 92.4% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) U.1 66 4 6.1% 1 +[L18F,A222V,T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] U.1 66 1 1.5% 1 +[L18F,A222V,P862S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FB.2 66 50 75.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,F486P,F490S] (consensus) FB.2 66 11 16.7% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,T478R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,F486P,F490S] FB.2 66 1 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V,I666V,S1170Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,F486P,F490S] FB.2 66 1 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,T478R,F486V,I666V,L1203F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,F486P,F490S] FB.2 66 1 1.5% 2 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,T478R,F486V,R634H,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,F486P,F490S] B.1.355 66 59 89.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.355 66 2 3.0% 1 +[V483F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.355 66 2 3.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.355 66 1 1.5% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.355 66 1 1.5% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAY.2 66 46 69.7% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.2 66 2 3.0% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.2 66 2 3.0% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F490S] XAY.2 66 2 3.0% 2 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A623T,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.2 66 2 3.0% 3 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A623T,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F490S] XBF.8 66 37 56.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.8 66 11 16.7% 2 +[K147E,W152Q,F157L,I210V,V213G,G257S,C1250F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.8 66 7 10.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.8 66 4 6.1% 2 +[K147E,W152R,M153I,F157L,I210V,V213G,G257S,Q1208H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.8 66 3 4.5% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] EW.1 66 46 69.7% 0 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,T478R,F486V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] (consensus) EW.1 66 3 4.5% 1 +[H69-,V70-,G181E,V213G,P251L,G339D,K444T,L452R,T478R,F486V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] EW.1 66 2 3.0% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,T478R,F486V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S,Q954H] EW.1 66 2 3.0% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,T478R,F486V,I624T,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] EW.1 66 1 1.5% 2 +[H69-,V70-,V213G,P251L,S316A,G339D,K444T,L452R,T478R,F486V,N856S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] FK.1.2.2 66 43 65.2% 0 +[K147E,W152R,F157L,T208S,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.2.2 66 19 28.8% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.2.2 66 1 1.5% 1 +[K147E,W152R,F157L,T208S,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,V1061F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.2.2 66 1 1.5% 2 +[S94Y,K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.2.2 66 1 1.5% 2 +[W152R,F157L,T208S,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,F486P,F490S] GK.1.2 66 38 57.6% 0 +[N185D,L455F,F456L,S704L] (consensus) GK.1.2 66 4 6.1% 2 +[N185D,L455F,F456L,S704L]-[G142D,K417N] GK.1.2 66 4 6.1% 3 +[N185D,L455F,F456L,E583Q,S704L]-[G142D,K417N] GK.1.2 66 3 4.5% 1 +[N185D,L455F,F456L,F486L,S704L]-[F486P] GK.1.2 66 2 3.0% 2 +[N185D,L455F,F456L,E583Q,S704L]-[K417N] B.1.215 66 64 97.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.215 66 1 1.5% 1 +[G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.215 66 1 1.5% 1 +[R190K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.4.1 65 51 78.5% 0 +[N450I] (consensus) FL.4.1 65 3 4.6% 1 +[T323I,N450I] FL.4.1 65 3 4.6% 1 +[F157L,N450I] FL.4.1 65 2 3.1% 1 +[N450I,T768I] FL.4.1 65 1 1.5% 2 +[T323I,N450I]-[R408S] B.1.273 65 60 92.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.273 65 2 3.1% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.273 65 1 1.5% 1 +[G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.273 65 1 1.5% 1 +[P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.273 65 1 1.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.17 65 31 47.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.17 65 22 33.8% 1 +[T19R,E156G,F157-,R158-,L452R,V622F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.17 65 3 4.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,P812L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.17 65 3 4.6% 2 +[T19R,T95N,E156G,F157-,R158-,L452R,V622F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.17 65 2 3.1% 2 +[T19R,E156G,F157-,R158-,T376I,L452R,V622F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BY.1.1.1 65 52 80.0% 0 +[K147E,W152R,F157L,N185D,H207R,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BY.1.1.1 65 3 4.6% 1 +[K147E,W152R,F157L,N185D,H207R,I210V,V213G,G257S,A262S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.1.1 65 3 4.6% 1 +[K147E,W152R,F157L,L179F,N185D,H207R,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.1.1 65 1 1.5% 1 +[K147E,W152R,F157L,N185D,H207R,I210V,V213G,G257S,L452R,F486S,V622F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.1.1 65 1 1.5% 1 +[K147E,W152R,F157L,N185D,H207R,I210V,V213G,G257S,L452R,F486S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] XBP 65 33 50.8% 0 +[K147E,W152R,F157L,I210V,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) XBP 65 21 32.3% 1 +[K147E,W152R,F157L,I210V,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBP 65 2 3.1% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBP 65 2 3.1% 2 +[K147E,W152R,F157L,I210V,V213G,G339D,K444T,L452R,F486V,A688V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBP 65 2 3.1% 1 +[K147E,W152R,F157L,I210V,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] XBF.9 65 46 70.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.9 65 4 6.2% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,R403K,D843G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.9 65 4 6.2% 1 +[K147E,W152R,F157L,I210F,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.9 65 2 3.1% 3 +[K147E,W152R,F157L,F186S,I210V,V213G,G257S,R403K,D843G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.9 65 2 3.1% 1 +[K147E,W152R,F157L,I210V,V213G,H245Y,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] B.1.1.459 65 51 78.5% 0 +[A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.459 65 2 3.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.459 65 2 3.1% 1 +[T22I,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.459 65 1 1.5% 1 +[A163V,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.459 65 1 1.5% 1 +[G261V,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.4.5 65 23 35.4% 0 +[T478R]-[T478K] (consensus) EG.4.5 65 12 18.5% 2 +[N164H,G261V,T478R]-[T478K] EG.4.5 65 2 3.1% 3 +[T478R,A942S]-[Q183E,K417N,T478K] EG.4.5 65 2 3.1% 3 +[N164H,G261V,T478R]-[K417N,T478K] EG.4.5 65 2 3.1% 4 +[N148T,N164H,G261V,T478R]-[K417N,T478K] FL.33.1 65 31 47.7% 0 +[T478R]-[T478K] (consensus) FL.33.1 65 17 26.2% 1 +[Q173R,T478R]-[T478K] FL.33.1 65 2 3.1% 2 +[D138H,Q173R,T478R]-[T478K] FL.33.1 65 2 3.1% 1 +[T478R,T547I]-[T478K] FL.33.1 65 1 1.5% 1 +[T478I]-[T478K] B.1.105 65 55 84.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.105 65 6 9.2% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.105 65 2 3.1% 1 +[T1006I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.105 65 1 1.5% 1 +[K356R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.105 65 1 1.5% 2 +[T676I,Y1047H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.3 65 63 96.9% 0 +[T478I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.3 65 1 1.5% 1 +[T478I,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.3 65 1 1.5% 1 +[A67V,T478I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAV 64 49 76.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAV 64 5 7.8% 1 +[H69-,V70-,I128V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAV 64 5 7.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAV 64 1 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAV 64 1 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] B.1.164 64 36 56.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.164 64 10 15.6% 1 +[E654K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.164 64 6 9.4% 1 +[A522S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.164 64 2 3.1% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.164 64 2 3.1% 3 +[A67T,S721G,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.344 64 45 70.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.344 64 2 3.1% 2 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.344 64 2 3.1% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.344 64 2 3.1% 2 +[V382L,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.344 64 2 3.1% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.10 64 43 67.2% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.10 64 10 15.6% 1 +[H69-,V70-,N439K,H1058Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.10 64 5 7.8% 1 +[H69-,V70-,N439K,D839A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.10 64 2 3.1% 1 +[L5F,H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.10 64 1 1.6% 2 +[L5F,H69-,V70-,N439K,R683W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.6.1 64 39 60.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.6.1 64 7 10.9% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.6.1 64 5 7.8% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.6.1 64 2 3.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.6.1 64 1 1.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1084Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] A.4 64 59 92.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.4 64 1 1.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.4 64 1 1.6% 1 +[A958S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.4 64 1 1.6% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.4 64 1 1.6% 1 +[W64L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GM.3.1 64 48 75.0% 0 +[D253G,N388K,P521S]-[G252V] (consensus) GM.3.1 64 4 6.2% 1 +[D253G,N388K,Y453H,P521S]-[G252V] GM.3.1 64 4 6.2% 1 +[D253G,N388K,P521S,A879S]-[G252V] GM.3.1 64 2 3.1% 1 +[D253G,N388K,P521S]-[G252V,R408S] GM.3.1 64 1 1.6% 1 +[D253G,N388K,F490Y,P521S]-[G252V,F490S] FE.1.1.2 64 33 51.6% 0 +[F456L,K1086R] (consensus) FE.1.1.2 64 5 7.8% 1 +[F456L,K1086R,M1237V] FE.1.1.2 64 4 6.2% 1 +[F456L,K1086R]-[K417N] FE.1.1.2 64 4 6.2% 2 +[G339Y,F456L,K1086R,M1237V]-[G339H] FE.1.1.2 64 3 4.7% 2 +[F456L,K1086R]-[R346T,K417N] BS.1 64 46 71.9% 0 +[V213N,+213GEG,G257V,G339D,L452R,G476-,T478N,+478K,S640F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] (consensus) BS.1 64 3 4.7% 4 +[V213G,G257V,G339D,L452R,G476-,T478N,+478K,S640F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] BS.1 64 3 4.7% 1 +[V213N,+213GEG,G257V,T299I,G339D,L452R,G476-,T478N,+478K,S640F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] BS.1 64 2 3.1% 2 +[V213N,+213GEG,G257V,G339D,L452R,G476-,T478N,+478K,S640F,T883I,A890V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] BS.1 64 1 1.6% 2 +[Y200C,V213N,+213GEG,G257V,G339D,L452R,G476-,T478N,+478K,S640F]-[H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] B.1.165 64 62 96.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.165 64 1 1.6% 1 +[V16I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.165 64 1 1.6% 1 +[K1245N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.1.4.4 63 55 87.3% 0 +[H69-,V70-,L176F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.4.4 63 2 3.2% 1 +[T19L,H69-,V70-,L176F,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4.4 63 1 1.6% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486V,I1210V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4.4 63 1 1.6% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BE.1.4.4 63 1 1.6% 1 +[H69-,V70-,L176F,V213G,G339D,V445F,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.68 63 61 96.8% 0 +[Q14R,L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.68 63 1 1.6% 2 +[L5F,Q14R,L18F,A222V,S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.68 63 1 1.6% 1 +[Q14R,L18F,Y145H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.452 63 45 71.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.452 63 6 9.5% 2 +[G184S,E1111A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.452 63 5 7.9% 1 +[D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.452 63 2 3.2% 1 +[D80N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.452 63 2 3.2% 1 +[E1111A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.32 63 49 77.8% 0 +[F486S]-[F486P] (consensus) XBB.1.32 63 2 3.2% 2 +[N148T,F486S,A701V]-[F486P] XBB.1.32 63 1 1.6% 1 +[F486S,A688V]-[F486P] XBB.1.32 63 1 1.6% 1 +[T22I,F486S]-[F486P] XBB.1.32 63 1 1.6% 2 +[Y453F,F486S]-[G142D,F486P] XBB.1.34 63 23 36.5% 0 +[P681R]-[P681H] (consensus) XBB.1.34 63 10 15.9% 1 +[P681R,I997V]-[P681H] XBB.1.34 63 8 12.7% 3 +[T478R,E554K,P681R,D1153Y]-[T478K,P681H] XBB.1.34 63 6 9.5% 1 +[V483F,P681R]-[P681H] XBB.1.34 63 4 6.3% 1 +[T478R,P681R]-[T478K,P681H] B.1.233 63 52 82.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.233 63 5 7.9% 1 +[L922F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.233 63 2 3.2% 1 +[F1103S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.233 63 1 1.6% 1 +[S1239R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.233 63 1 1.6% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DT.3 63 53 84.1% 0 +[H69-,V70-,M153I,L176F,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DT.3 63 4 6.3% 1 +[H69-,V70-,M153I,L176F,V213G,G339D,K444T,L452R,F486V,T547I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.3 63 1 1.6% 1 +[H69-,V70-,M153I,L176F,V213G,G339D,K444T,L452R,P463S,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.3 63 1 1.6% 3 +[H69-,V70-,M153I,L176F,I203V,V213G,G339D,K444T,L452R,F486V,T547I,S1170F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.3 63 1 1.6% 2 +[H69-,V70-,M153I,L176F,I203V,V213G,G339D,K444T,L452R,F486V,T547I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.112.1 63 51 81.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.112.1 63 8 12.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.1 63 2 3.2% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.1 63 1 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112.1 63 1 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P589S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CP.2 63 54 85.7% 0 +[H69-,V70-,V213G,N334K,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.2 63 5 7.9% 1 +[H69-,V70-,V213G,N334K,G339D,L452R,F486V,E554K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.2 63 1 1.6% 1 +[L5F,H69-,V70-,V213G,N334K,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.2 63 1 1.6% 1 +[H69-,V70-,V213G,N334K,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,D796Y] CP.2 63 1 1.6% 1 +[H69-,V70-,V213G,N334K,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BQ.1.32 63 53 84.1% 0 +[H69-,V70-,V213G,Y248S,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.32 63 2 3.2% 2 +[H69-,V70-,V213G,Y248S,G339D,K444T,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.32 63 1 1.6% 3 +[A27-,I68F,H69-,V70-,V213G,Y248S,G339D,K444T,L452R,F486V]-[P25-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.32 63 1 1.6% 1 +[H69-,V70-,V213G,Y248S,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.32 63 1 1.6% 1 +[H69-,V70-,V213G,Y248S,G339D,K444T,L452R,F486V,A892V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EG.1.7 63 41 65.1% 0 +[E156V,Q613H] (consensus) EG.1.7 63 6 9.5% 1 +[E156V,P217S,Q613H] EG.1.7 63 3 4.8% 1 +[T76I,E156V,Q613H] EG.1.7 63 2 3.2% 1 +[E156V,Q613H,K1045E] EG.1.7 63 2 3.2% 1 +[E156V,Q613H,M1233I] B.1.1.165 63 58 92.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.165 63 3 4.8% 1 +[H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.165 63 1 1.6% 1 +[P728L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.165 63 1 1.6% 2 +[A243-,L244-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.15 63 47 74.6% 0 +[D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.15 63 10 15.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.15 63 5 7.9% 1 +[S750N,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.15 63 1 1.6% 1 +[L84I,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.539 62 41 66.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.539 62 8 12.9% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.539 62 7 11.3% 2 +[L5F,A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.539 62 1 1.6% 1 +[M731I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.539 62 1 1.6% 1 +[A348S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.98 62 23 37.1% 0 +[E554K] (consensus) XBB.1.5.98 62 12 19.4% 1 +[E554K]-[T478K] XBB.1.5.98 62 4 6.5% 2 +[T478R,E554K,Y674F]-[T478K] XBB.1.5.98 62 3 4.8% 1 +[E554K,V1122L] XBB.1.5.98 62 2 3.2% 1 +[T478N,E554K]-[T478K] EU.1.1.2 62 49 79.0% 0 +[I410V,P521S,A1070S] (consensus) EU.1.1.2 62 8 12.9% 1 +[T284I,I410V,P521S,A1070S] EU.1.1.2 62 1 1.6% 1 +[H146K,I410V,P521S,A1070S]-[H146Q] EU.1.1.2 62 1 1.6% 1 +[I410V,A1070S] EU.1.1.2 62 1 1.6% 2 +[T284I,I410V,P521S,A1070S,P1162L] B.1.1.180 62 58 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.180 62 1 1.6% 1 +[M1050I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.180 62 1 1.6% 1 +[T1238I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.180 62 1 1.6% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.180 62 1 1.6% 1 +[Q183H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CF.1 62 36 58.1% 0 +[H69-,V70-,K97T,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CF.1 62 9 14.5% 1 +[H66R,H69-,V70-,K97T,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CF.1 62 5 8.1% 1 +[H69-,V70-,K97T,V213G,S256L,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CF.1 62 2 3.2% 3 +[H66R,H69F,V70-,S71-,K97T,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CF.1 62 1 1.6% 1 +[H69-,V70-,K97T,V213G,G339D,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.68 62 49 79.0% 0 +[P521T] (consensus) XBB.1.5.68 62 4 6.5% 1 +[P521T,S939Y] XBB.1.5.68 62 1 1.6% 1 +[R190K,P521T] XBB.1.5.68 62 1 1.6% 1 +[T478R,P521T]-[T478K] XBB.1.5.68 62 1 1.6% 2 +[L5F,P521T]-[V83A] JN.2.2 62 30 48.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.2.2 62 11 17.7% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.2 62 6 9.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,N487D,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.2 62 2 3.2% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.2 62 2 3.2% 5 +[R21T,S50L,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.177.78 62 42 67.7% 0 +[A222V,S254F,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.78 62 20 32.3% 1 +[A222V,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.16 62 61 98.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.16 62 1 1.6% 1 +[E1182K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.12 62 57 91.9% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.12 62 1 1.6% 2 +[H69S,V70I,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.12 62 1 1.6% 1 +[H69-,V70-,N439K,L455F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.12 62 1 1.6% 1 +[H69-,V70-,N439K,D1146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.12 62 1 1.6% 1 +[H69-,V70-,W258L,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.25 62 61 98.4% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.25 62 1 1.6% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H] BM.2.1 62 42 67.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.2.1 62 9 14.5% 1 +[G72V,K147E,W152R,F157L,I210V,V213G,G257S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.2.1 62 2 3.2% 2 +[G72V,K147E,W152R,F157L,I210V,V213G,G257S,F486V,I569V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.2.1 62 1 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486V,I1130M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.2.1 62 1 1.6% 2 +[K147E,S151N,W152R,F157L,I210A,V213G,G257S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.177.36 61 23 37.7% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.36 61 22 36.1% 1 +[A222V,G932S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.36 61 11 18.0% 2 +[A222V,R1091H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.36 61 2 3.3% 2 +[A222V,Q493L,G932S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.36 61 1 1.6% 1 +[A222V,H1083Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XD 61 44 72.1% 0 +[T19R,T95I,E156G,F157-,R158-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) XD 61 5 8.2% 4 +[T19R,Q23P,T95I,E156G,F157-,R158-,N211-,L212I,+214ELE,G339D,S371L,Q493R,G496S,T547K,T719S,M740I,N856K,L981F]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XD 61 4 6.6% 3 +[T19R,T95I,E156G,F157-,R158-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XD 61 3 4.9% 1 +[T19R,T95I,E156G,F157-,R158-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,T961M,L981F]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XD 61 2 3.3% 1 +[T19R,T95I,E156G,F157-,R158-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,F565L,N856K,L981F]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.1.355 61 31 50.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.355 61 6 9.8% 1 +[N481S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.355 61 4 6.6% 2 +[L5F,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.355 61 4 6.6% 1 +[S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.355 61 4 6.6% 3 +[L18F,A348S,S371T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AK.1 61 57 93.4% 0 +[V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AK.1 61 1 1.6% 1 +[V635A,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AK.1 61 1 1.6% 1 +[I100T,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AK.1 61 1 1.6% 2 +[A67V,G769V,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AK.1 61 1 1.6% 1 +[V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.83 61 54 88.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.83 61 2 3.3% 1 +[P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.83 61 1 1.6% 1 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.83 61 1 1.6% 1 +[I1221V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.83 61 1 1.6% 1 +[A1070S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.134 61 52 85.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.134 61 1 1.6% 1 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.134 61 1 1.6% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.134 61 1 1.6% 2 +[E96D,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.134 61 1 1.6% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.238 61 36 59.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.238 61 15 24.6% 1 +[V1068I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.238 61 8 13.1% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.238 61 1 1.6% 2 +[T323I,V1068I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.238 61 1 1.6% 1 +[G181V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.554 61 61 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.5.93 61 45 73.8% 0 (consensus) XBB.1.5.93 61 5 8.2% 1 -[K417N] XBB.1.5.93 61 4 6.6% 1 +[E96D] XBB.1.5.93 61 2 3.3% 1 +[C1235F] XBB.1.5.93 61 1 1.6% 1 -[G252V] B.1.258.5 61 54 88.5% 0 +[H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.5 61 4 6.6% 1 +[H69-,V70-,L189F,N439K,A647V,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.5 61 2 3.3% 1 +[L5F,H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.5 61 1 1.6% 1 +[H69-,V70-,L189F,N439K,T676I,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.26 61 54 88.5% 0 +[A222V,E583Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.26 61 3 4.9% 1 +[L5F,A222V,E583Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.26 61 3 4.9% 2 +[A222V,E583Q,A672V,Q872L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.26 61 1 1.6% 1 +[A222V,E583Q,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.29 60 56 93.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E554Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.29 60 1 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E554Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.29 60 1 1.7% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,E554Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.29 60 1 1.7% 1 +[H69-,V70-,K150E,V213G,G339D,K444T,L452R,F486V,E554Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.29 60 1 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E554Q,E583D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.1.320 60 55 91.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.320 60 2 3.3% 1 +[Y1209F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.320 60 1 1.7% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.320 60 1 1.7% 1 +[S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.320 60 1 1.7% 1 +[G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.456 60 22 36.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.456 60 7 11.7% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.456 60 5 8.3% 2 +[H49Y,E132A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.456 60 3 5.0% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.456 60 3 5.0% 3 +[L54F,I1114F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.26 60 22 36.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.26 60 20 33.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.26 60 8 13.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.26 60 1 1.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] JN.1.26 60 1 1.7% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,G482-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.563 60 46 76.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.563 60 11 18.3% 1 +[P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.563 60 1 1.7% 1 +[E484G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.563 60 1 1.7% 1 +[E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.563 60 1 1.7% 1 +[G261V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBR 60 49 81.7% 0 +[K147E,W152R,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) XBR 60 5 8.3% 1 +[K147E,W152R,F157L,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBR 60 1 1.7% 1 +[K147E,W152R,F157L,V213G,R246K,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBR 60 1 1.7% 1 +[K147E,W152R,F157L,V213G,G339D,K444T,L452R,F486V,P681R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S,P681H] XBR 60 1 1.7% 1 +[K147E,W152R,F157L,V213G,G339D,K444T,L452R,F486V,A1026S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BC.2 60 43 71.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BC.2 60 4 6.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EGE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BC.2 60 3 5.0% 1 +[A67V,H69-,V70-,T95I,S98F,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BC.2 60 3 5.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,D1146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BC.2 60 1 1.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,L189F,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.31 60 51 85.0% 0 +[T19R,E156G,F157-,R158-,L452R,S640P,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.31 60 5 8.3% 1 +[T19R,E156G,F157-,R158-,L452R,S640P,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.31 60 2 3.3% 1 +[T19R,E156G,F157-,R158-,L452R,T618I,S640P,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.31 60 1 1.7% 1 +[T19R,E156G,F157-,R158-,N165S,L452R,S640P,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.31 60 1 1.7% 2 +[T19R,E156G,F157-,R158-,L452R,S640P,P681R,D950N,V1104L,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.3.10 60 43 71.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.10 60 4 6.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,M1237I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.10 60 4 6.7% 5 +[K147E,W152R,F157L,I210V,+212AA,+213E,+214R,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.10 60 2 3.3% 1 +[K147E,W152R,F157L,I210V,V213G,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.10 60 1 1.7% 2 +[K147E,W152R,F157L,Q183H,I210V,V213G,G257S,K356T,N679R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,N679K] GK.2.3 60 52 86.7% 0 +[K356T,L455F,F456L,V511I] (consensus) GK.2.3 60 2 3.3% 1 +[K356T,L455F,F456L,V511I,S1252P] GK.2.3 60 1 1.7% 2 +[A67S,K356T,L455F,F456L,V511I,G639S] GK.2.3 60 1 1.7% 1 +[K356T,L455F,F456L,V511I,Y837H] GK.2.3 60 1 1.7% 1 +[K356T,L455F,F456L,V511I,P807S] FT.3.1 60 40 66.7% 0 +[Q52H,T478R,D1168H]-[T478K] (consensus) FT.3.1 60 3 5.0% 2 +[Q52H,T478R,T547I,A942S,D1168H]-[T478K] FT.3.1 60 2 3.3% 1 +[Q52H,T478R,S704L,D1168H]-[T478K] FT.3.1 60 2 3.3% 1 +[Q52H,T478R,T547I,D1168H]-[T478K] FT.3.1 60 2 3.3% 1 +[Q52H,T478R,D1168H]-[K417N,T478K] FL.23 60 16 26.7% 0 +[H146K]-[H146Q] (consensus) FL.23 60 6 10.0% 1 FL.23 60 5 8.3% 2 +[H146K,S494P,P521T]-[H146Q] FL.23 60 4 6.7% 1 +[H146K]-[G142D,H146Q] FL.23 60 2 3.3% 2 -[Y144-] FT.1 60 50 83.3% 0 +[I197V] (consensus) FT.1 60 2 3.3% 1 +[I197V,H1159R] FT.1 60 1 1.7% 6 +[I197V]-[S477N,T478K,E484A,F486P,F490S,Q498R] FT.1 60 1 1.7% 1 +[I197V]-[Q183E] FT.1 60 1 1.7% 1 +[I197V,D627E] BF.42 60 60 100.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CR.2 60 50 83.3% 0 +[H69-,V70-,Y145H,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CR.2 60 4 6.7% 1 +[H69-,V70-,Y145H,V213G,G339D,K444R,L452R,F486V,L552I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CR.2 60 2 3.3% 3 +[L5F,H69-,V70-,Y145H,V213G,G339D,L452R,F486V,T1006S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CR.2 60 1 1.7% 3 +[H69-,V70-,+146Y,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CR.2 60 1 1.7% 1 +[H69-,V70-,Y145H,V213G,G339D,K444R,L452R,F486V,L922V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.113 60 51 85.0% 0 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.113 60 4 6.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.113 60 1 1.7% 1 +[L54F,T1077I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.113 60 1 1.7% 1 +[L54F,S155I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.113 60 1 1.7% 4 +[L141-,G142-,V143-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.629 59 30 50.8% 0 +[K182R,L452R,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] (consensus) B.1.629 59 9 15.3% 1 +[K182R,T259I,L452R,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] B.1.629 59 7 11.9% 1 +[K182R,A348S,L452R,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] B.1.629 59 2 3.4% 1 +[K182R,L452R,G1124C,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] B.1.629 59 2 3.4% 1 +[K182R,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,Q954H,N969K] CT.1 59 30 50.8% 0 +[H69-,V70-,V213G,G339D,K356T,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CT.1 59 10 16.9% 1 +[H69-,V70-,V213G,G339D,K356T,K444T,L452R,F486V,R765H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CT.1 59 7 11.9% 1 +[L5F,H69-,V70-,V213G,G339D,K356T,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CT.1 59 2 3.4% 1 +[H69-,V70-,V213G,G339D,K356T,K444T,L452R,F486V,T1006I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CT.1 59 1 1.7% 2 +[H69-,V70-,V213G,G339D,K356T,K444T,L452R,F486V,R765H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.380 59 34 57.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.380 59 10 16.9% 2 +[Q321L,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.380 59 2 3.4% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.380 59 2 3.4% 3 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,N764K,D796Y,Q954H,N969K] B.1.380 59 1 1.7% 1 +[Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.39 59 48 81.4% 0 +[F486S]-[F486P] (consensus) XBB.1.39 59 1 1.7% 1 +[F486S,D936H]-[F486P] XBB.1.39 59 1 1.7% 1 +[Y453F,F486S]-[F486P] XBB.1.39 59 1 1.7% 1 +[F486S,V1177I]-[F486P] XBB.1.39 59 1 1.7% 3 +[F486S,R567I,D936H]-[G252V,F486P] BM.1.1.4 59 27 45.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F486S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.1.1.4 59 8 13.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F486S,T547K,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.4 59 4 6.8% 4 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S,K356T,F486S,T572I,S1147L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BM.1.1.4 59 3 5.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F486S,T572I,C1248F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.4 59 2 3.4% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F486S,T547K,T572I,P681Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,P681H] B.1.598 59 56 94.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.598 59 1 1.7% 1 +[E1150D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.598 59 1 1.7% 1 +[A876S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.598 59 1 1.7% 1 +[S477G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.344 59 59 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.132 59 52 88.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.132 59 2 3.4% 2 +[G142C,R214C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.132 59 1 1.7% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.132 59 1 1.7% 1 +[S151I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.132 59 1 1.7% 2 +[P217S,V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CP.1.2 59 41 69.5% 0 +[H69-,V70-,K150N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.1.2 59 10 16.9% 1 +[H69-,V70-,K150N,V213G,G339D,L452R,F486V,G1267R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.1.2 59 3 5.1% 1 +[H69-,V70-,K150N,V213G,G339D,L452R,F486V,S813G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.1.2 59 1 1.7% 2 +[H69-,V70-,T95N,K150N,V213G,G339D,L452R,F486V,Q804K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.1.2 59 1 1.7% 2 +[H69-,V70-,K150N,V213G,G339D,L452R,F486V,P621S,G1267R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] FL.3.4 59 48 81.4% 0 (consensus) FL.3.4 59 8 13.6% 1 +[P1263Q] FL.3.4 59 2 3.4% 1 +[S349P] FL.3.4 59 1 1.7% 1 -[R408S] XAJ 58 27 46.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAJ 58 23 39.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,S704L,D1163V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAJ 58 2 3.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAJ 58 1 1.7% 3 +[V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAJ 58 1 1.7% 2 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.366 58 25 43.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.366 58 22 37.9% 1 +[A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.366 58 3 5.2% 1 +[V382L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.366 58 2 3.4% 2 +[L18F,A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.366 58 1 1.7% 1 +[D1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.75 58 44 75.9% 0 +[A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.75 58 5 8.6% 1 +[W152L,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.75 58 2 3.4% 1 +[G769V,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.75 58 2 3.4% 2 +[S689I,A846V,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.75 58 2 3.4% 1 +[A846V,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JF.2 58 56 96.6% 0 +[E180V,F456L,T478R,Q675H]-[T478K] (consensus) JF.2 58 1 1.7% 1 +[E180V,F456L,T478R,Q675H,F817V]-[T478K] JF.2 58 1 1.7% 3 +[E180V,F456L,T478R,Q675H]-[Y144-,N440K,T478K,F490S] GM.1 58 43 74.1% 0 +[D253G,P521S,P621S]-[G252V] (consensus) GM.1 58 3 5.2% 1 +[D253G,P521S,P621S,D745E]-[G252V] GM.1 58 2 3.4% 1 +[D253G,F486R,P521S,P621S]-[G252V,F486P] GM.1 58 2 3.4% 2 +[L8F,D253G,P521S,P621S,D745E]-[G252V] GM.1 58 2 3.4% 1 +[G75V,D253G,P521S,P621S]-[G252V] CH.1.1.21 58 49 84.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,N481Y,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.21 58 4 6.9% 1 +[K147E,W152R,F157L,G184V,I210V,V213G,G257S,K444T,L452R,N481Y,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.21 58 2 3.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,N481Y,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,S371F,V445P,F486P,F490S] CH.1.1.21 58 1 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,S459F,N481Y,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.21 58 1 1.7% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,N481Y,F486S,A1020V,D1127G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.282 58 19 32.8% 0 +[C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.282 58 14 24.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.282 58 10 17.2% 2 +[V70F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.282 58 6 10.3% 2 +[A522S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.282 58 4 6.9% 2 +[L226F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.482 57 27 47.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.482 57 25 43.9% 1 +[T678I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.482 57 1 1.8% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.482 57 1 1.8% 4 +[N74K,E484D,R682W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.482 57 1 1.8% 11 +[I68-,H69-,V70-,S71-,G72-,N74-,G75-,T76-,P812L,Q853L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.423 57 49 86.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.423 57 1 1.8% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.423 57 1 1.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.423 57 1 1.8% 4 +[L5F,P217S,A701V,I844S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.423 57 1 1.8% 1 +[S1242I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.420 57 44 77.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.420 57 4 7.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.420 57 3 5.3% 1 +[I934V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.420 57 1 1.8% 1 +[D294G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.420 57 1 1.8% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FW.1 57 43 75.4% 0 +[K356T,R403K,F486S,A701V]-[F486P] (consensus) FW.1 57 2 3.5% 2 +[K356T,R403K,F486S,S494P,Q675H,A701V]-[F486P] FW.1 57 2 3.5% 2 +[K356T,R403K,F486S,A701V,T1116A,E1150V]-[F486P] FW.1 57 1 1.8% 1 +[K356T,R403K,F486S,A701V]-[T19I,F486P] FW.1 57 1 1.8% 2 +[G261V,K356T,R403K,F486S,A701V,G1085R]-[F486P] B.1.1.347 57 47 82.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.347 57 3 5.3% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.347 57 3 5.3% 2 +[H49Y,A924S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.347 57 1 1.8% 2 +[A67S,S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.347 57 1 1.8% 1 +[D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.31.2 57 48 84.2% 0 +[Y453F,T478R,F486S]-[T478K,F486P] (consensus) XBB.1.31.2 57 1 1.8% 1 +[Y453F,T478R,F486S]-[G142D,T478K,F486P] XBB.1.31.2 57 1 1.8% 2 +[Y453F,T478R,F486S,V1104L]-[G142D,T478K,F486P] XBB.1.31.2 57 1 1.8% 1 +[A264V,Y453F,T478R,F486S]-[T478K,F486P] XBB.1.31.2 57 1 1.8% 1 +[Y453F,T478R,N481Y,F486S]-[T478K,F486P] XBJ.2 57 40 70.2% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) XBJ.2 57 3 5.3% 2 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,E484A,F486P,F490S] XBJ.2 57 2 3.5% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,A701S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ.2 57 2 3.5% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,A893V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ.2 57 1 1.8% 1 +[N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBU 57 36 63.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] (consensus) XBU 57 7 12.3% 1 +[K147E,W152R,F157L,N185T,I210V,V213G,G257S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] XBU 57 2 3.5% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,K417N,V445P,G446S,F486P,F490S] XBU 57 2 3.5% 2 +[K147E,W152R,F157L,N185T,I210V,V213G,G257S,T385I,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] XBU 57 1 1.8% 1 +[K147E,W152R,F157L,N185Y,I210V,V213G,G257S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] B.52 57 49 86.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.52 57 3 5.3% 6 +[H69-,V70-,L179I,S255F,L452R,D614N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.52 57 1 1.8% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.52 57 1 1.8% 1 +[W64L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.52 57 1 1.8% 1 +[L179I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.513 57 55 96.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.513 57 1 1.8% 1 +[P728L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.513 57 1 1.8% 1 +[G181V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.294 57 35 61.4% 0 +[L585F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.294 57 19 33.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.294 57 2 3.5% 2 +[Q779H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.294 57 1 1.8% 2 +[M177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.5.2.2 57 41 71.9% 0 +[F456L] (consensus) EG.5.2.2 57 2 3.5% 3 +[N17D,S221L,F456L,S494P] EG.5.2.2 57 2 3.5% 4 +[F456L,G476-,T478N,+478K]-[S477N,T478K] EG.5.2.2 57 2 3.5% 2 +[H146K,A348S,F456L]-[H146Q] EG.5.2.2 57 1 1.8% 2 +[N17D,F456L,S494P] BJ.1 57 36 63.2% 0 +[V483A,F490V,Q493R,G798D,S1003I]-[G252V,N460K,F486P,F490S] (consensus) BJ.1 57 4 7.0% 3 +[V483A,F490V,Q493R,G798D,S1003I]-[G252V,S373P,S375F,T376A,N460K,F486P,F490S] BJ.1 57 3 5.3% 1 +[V483A,F490V,Q493R,G798D,S1003I,S1170Y]-[G252V,N460K,F486P,F490S] BJ.1 57 2 3.5% 1 +[V483A,F490V,Q493R,S1003I]-[G252V,N460K,F486P,F490S] BJ.1 57 2 3.5% 1 +[V483A,F490V,Q493R,G798D,S1003I,T1117I]-[G252V,N460K,F486P,F490S] FF.1 57 52 91.2% 0 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V,Q613H,A688V,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) FF.1 57 2 3.5% 1 +[H69-,V70-,I210T,V213G,S256L,G339D,K444T,L452R,F486V,Q613H,A688V,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FF.1 57 1 1.8% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V,Q613H,A688V,Q949K,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FF.1 57 1 1.8% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V,Q613H,A688V,V1164I,I1210V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FF.1 57 1 1.8% 1 +[L5F,H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V,Q613H,A688V,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FL.31.1 57 29 50.9% 0 +[D80H,T478R,Q613H]-[T478K] (consensus) FL.31.1 57 9 15.8% 1 +[D80H,T478R,Q613H,E654K]-[T478K] FL.31.1 57 2 3.5% 1 +[D80H,T478R,Q613H]-[R408S,T478K] FL.31.1 57 2 3.5% 2 +[D80H,V213D,T478R,Q613H,E654K]-[V213E,T478K] FL.31.1 57 2 3.5% 4 +[D80H,A243-,L244-,T478R,Q613H,E654K,D1260N]-[T478K] B.1.1.130 57 33 57.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.130 57 24 42.1% 1 +[K444R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.323 56 55 98.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.323 56 1 1.8% 1 +[F220I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAE 56 48 85.7% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAE 56 5 8.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAE 56 1 1.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] XAE 56 1 1.8% 1 +[V213G,G339D,Q493R,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAE 56 1 1.8% 2 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,K417N,V445P,G446S,N460K,F486P,F490S] B.1.36.23 56 52 92.9% 0 +[A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.23 56 3 5.4% 1 +[G261V,A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.23 56 1 1.8% 1 +[L5-,A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.360 56 56 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.552 56 54 96.4% 0 +[T859I,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.552 56 1 1.8% 1 +[R682W,T859I,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.552 56 1 1.8% 1 +[T859I,T941I,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.1.2 56 13 23.2% 0 +[P9L,C136F,R190S,D215G,A243-,L244-,Y449H,E484K,T716I,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] C.1.2 56 9 16.1% 4 +[P9L,P25L,C136F,W152R,R190S,D215G,A243-,L244-,Y449H,E484K,T716I,T859N,A879T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] C.1.2 56 5 8.9% 3 +[P9L,P25L,C136F,R190S,D215G,A243-,L244-,Y449H,E484K,T716I,T859N,H1101Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] C.1.2 56 4 7.1% 2 +[P9L,P25L,C136F,R190S,D215G,A243-,L244-,P384L,Y449H,E484K,T716I,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] C.1.2 56 4 7.1% 5 +[P9L,P25L,C136F,R190S,D215G,A243-,L244-,Y449H,E484K,T716I,T859N,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] AY.120.2 56 26 46.4% 0 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.120.2 56 13 23.2% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2 56 1 1.8% 2 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,R765H,D950N,K1073T]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2 56 1 1.8% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,V267L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2 56 1 1.8% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1184G]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.34 56 54 96.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.34 56 2 3.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FU.5 56 30 53.6% 0 +[K97E,E180V,T478R,T547I]-[T478K] (consensus) FU.5 56 13 23.2% 2 +[K97E,E156Q,E180V,T478R,T547I,E554K]-[T478K] FU.5 56 2 3.6% 1 +[K97E,E180V,T478R,T547I,S875A]-[T478K] FU.5 56 1 1.8% 1 +[T19L,K97E,E180V,T478R,T547I]-[T19I,T478K] FU.5 56 1 1.8% 3 +[K97E,E156Q,E180V,T478R,T547I,E554K]-[K417N,T478K] FL.15.2 56 25 44.6% 0 +[Q14H,F456L] (consensus) FL.15.2 56 7 12.5% 1 +[Q14H,L455F,F456L] FL.15.2 56 7 12.5% 1 +[Q14H,F456L,V687I] FL.15.2 56 4 7.1% 2 +[Q14H,F456L,V687I]-[Y144-] FL.15.2 56 2 3.6% 1 +[Q14H,F456L,P1162L] B.1.415 55 50 90.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.415 55 4 7.3% 1 +[P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.415 55 1 1.8% 1 +[M177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.528 55 42 76.4% 0 +[D138Y,N450K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.528 55 4 7.3% 1 +[D138Y,N450K,P681R,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.528 55 2 3.6% 36 +[M153I,V213G,T299I,G339D,R346K,E484K,G1219C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,V445P,G446S,N460K,E484A,F486P,F490S] B.1.1.528 55 1 1.8% 1 +[Q134E,D138Y,N450K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.528 55 1 1.8% 7 +[D138Y,I210-,L242-,A243-,L244-,P681R,A1078V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GJ.2 55 28 50.9% 0 +[K182N,D253G,P521S,I1114S]-[G252V] (consensus) GJ.2 55 13 23.6% 1 +[H146K,K182N,D253G,P521S,I1114S]-[H146Q,G252V] GJ.2 55 2 3.6% 2 +[H146K,K182N,D253G,G485D,P521S,I1114S]-[H146Q,G252V] GJ.2 55 2 3.6% 3 +[Y145K,H146K,K182N,D253G,P521S,I1114S]-[Y144-,H146Q,G252V] GJ.2 55 1 1.8% 2 +[K182N,D253G,P521S,E654V,L938F,I1114S]-[G252V] B.1.212 55 48 87.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.212 55 1 1.8% 1 +[P1263S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.212 55 1 1.8% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.212 55 1 1.8% 1 +[S155I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.212 55 1 1.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.637.1 55 51 92.7% 0 +[H69-,V70-,D80G,E96Q,F157S,L244-,H245-,R246-,S247-,A264V,G446R,L452R,T478R,P681R,T859N,D936H,D950H,N978S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.637.1 55 2 3.6% 7 +[R78S,D80G,F157S,D215H,L244-,H245-,R246-,S247-,G446R,L452R,T478R,P681R,T859N,D950H,N978S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.637.1 55 1 1.8% 4 +[H69-,V70-,D80G,F157S,L244-,H245-,R246-,S247-,A264V,G446R,L452R,T478R,P681R,T859N,D950H,E1144Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.637.1 55 1 1.8% 1 +[H69-,V70-,D80G,E96Q,F157S,L244-,H245-,R246-,S247-,A264V,G446R,L452R,P681R,T859N,D936H,D950H,N978S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.2 55 20 36.4% 0 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.2 55 19 34.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.2 55 4 7.3% 1 +[A264S,N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.2 55 3 5.5% 2 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.2 55 2 3.6% 1 +[H146P,N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.79 55 36 65.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.79 55 8 14.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.79 55 2 3.6% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H,R646H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.79 55 2 3.6% 2 +[H69-,V70-,V213G,S255F,G339D,P384S,K444T,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.79 55 1 1.8% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q493Y,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.373 55 41 74.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.373 55 2 3.6% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.373 55 2 3.6% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.373 55 1 1.8% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.373 55 1 1.8% 1 +[F543L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.15.1 55 41 74.5% 0 (consensus) XBB.1.15.1 55 3 5.5% 1 -[Y144-] XBB.1.15.1 55 2 3.6% 2 +[E516G]-[K417N] XBB.1.15.1 55 2 3.6% 2 -[Y144-,S371F] XBB.1.15.1 55 1 1.8% 1 +[N211D] B.1.1.15 55 46 83.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.15 55 4 7.3% 4 +[R21T,T299I,T415A,S477R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.15 55 2 3.6% 1 +[N532Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.15 55 1 1.8% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.15 55 1 1.8% 2 +[H245R,V551I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.71 55 50 90.9% 0 +[H69-,V70-,K182E,V213G,P251L,G339D,K444T,G446R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.71 55 5 9.1% 1 +[H69-,V70-,K182E,V213G,P251L,G339D,K444T,G446R,L452R,F486V,T573I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BN.1.3.13 55 16 29.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,A264D,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.13 55 10 18.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.13 55 6 10.9% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P] BN.1.3.13 55 5 9.1% 1 +[F32L,K147E,W152R,F157L,I210V,V213G,G257S,A264D,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.13 55 4 7.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,A264D,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P] EG.5.1.10 55 36 65.5% 0 +[Q52H,F456L] (consensus) EG.5.1.10 55 7 12.7% 1 +[Q52H,F456L,T883I] EG.5.1.10 55 2 3.6% 1 +[Q52H,E132V,F456L] EG.5.1.10 55 2 3.6% 1 +[Q52H,H146K,F456L]-[H146Q] EG.5.1.10 55 2 3.6% 1 +[Q52H,F456L]-[R408S] DN.1.1.4 55 40 72.7% 0 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,N481S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.1.1.4 55 5 9.1% 2 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,T478R,N481S,F486V,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] DN.1.1.4 55 4 7.3% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,N481S,F486V,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1.1.4 55 2 3.6% 1 +[H69-,V70-,K147N,V213G,S255F,G339D,K444T,L452R,N481S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1.1.4 55 1 1.8% 1 +[H69-,V70-,K147N,V213G,R214H,G339D,K444T,L452R,N481S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.45 55 55 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.256 55 55 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.291 54 43 79.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.291 54 2 3.7% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.291 54 2 3.7% 1 +[D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.291 54 1 1.9% 1 +[V911I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.291 54 1 1.9% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.4 54 54 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) BF.10.1 54 42 77.8% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] (consensus) BF.10.1 54 10 18.5% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,R646H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] BF.10.1 54 1 1.9% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,E1262V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] BF.10.1 54 1 1.9% 1 +[H69-,V70-,S98F,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] B.1.1.290 54 47 87.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.290 54 6 11.1% 1 +[T95A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.290 54 1 1.9% 1 +[A688S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.32 54 34 63.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.32 54 10 18.5% 2 +[W152R,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.32 54 3 5.6% 1 +[V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.32 54 2 3.7% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.32 54 1 1.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] BA.1.22 54 40 74.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.22 54 2 3.7% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.22 54 2 3.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,V1128I]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.22 54 1 1.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.22 54 1 1.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] GJ.1.2.1 54 22 40.7% 0 +[K182N,D253G,N450D,P521S]-[G252V] (consensus) GJ.1.2.1 54 4 7.4% 2 +[K182N,D253G,N450D,T478R,P521S,P809S]-[G252V,T478K] GJ.1.2.1 54 4 7.4% 1 +[K182N,D253G,N450D,P521S,P809S]-[G252V] GJ.1.2.1 54 4 7.4% 1 +[K182N,D253G,N450D,T478R,P521S]-[G252V,T478K] GJ.1.2.1 54 3 5.6% 1 +[K182N,D253G,N450D,P521S]-[T19I,G252V] XBJ.1.1 54 42 77.8% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) XBJ.1.1 54 4 7.4% 1 +[G75D,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ.1.1 54 3 5.6% 2 +[I68T,Y144F,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ.1.1 54 1 1.9% 2 +[G75D,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D,A1070V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ.1.1 54 1 1.9% 1 +[M153T,N164K,V213G,T240I,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBB.2.9 54 16 29.6% 0 +[D253G]-[G252V] (consensus) XBB.2.9 54 10 18.5% 1 +[D253G,E471Q]-[G252V] XBB.2.9 54 5 9.3% 1 +[D253G,T478R]-[G252V,T478K] XBB.2.9 54 2 3.7% 1 +[D253G,H1101Y]-[G252V] XBB.2.9 54 1 1.9% 1 +[D253G,T478N]-[G252V,T478K] XBB.1.9.7 54 32 59.3% 0 +[T478R]-[T478K] (consensus) XBB.1.9.7 54 3 5.6% 1 +[T478R,V1264L]-[T478K] XBB.1.9.7 54 2 3.7% 1 +[T478R,N1074K]-[T478K] XBB.1.9.7 54 2 3.7% 1 +[T478R]-[G142D,T478K] XBB.1.9.7 54 1 1.9% 2 +[T478R,E654D,D1153Y]-[T478K] GK.1.4 54 36 66.7% 0 +[S98F,L455F,F456L,T478R,S704L]-[T478K] (consensus) GK.1.4 54 2 3.7% 1 +[S98F,L455F,F456L,T478R,S704L,L858I]-[T478K] GK.1.4 54 2 3.7% 1 +[S98F,L455F,F456L,T478R,E554Q,S704L]-[T478K] GK.1.4 54 2 3.7% 1 +[Q52H,S98F,L455F,F456L,T478R,S704L]-[T478K] GK.1.4 54 1 1.9% 1 +[S98F,L455F,F456L,T478R,S596I,S704L]-[T478K] B.26 54 47 87.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.26 54 4 7.4% 1 -[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.26 54 2 3.7% 1 +[A831V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.26 54 1 1.9% 1 +[I233T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GS.5 53 26 49.1% 0 +[R190S,Q218H,D253G,T478R,P521S]-[G252V,T478K] (consensus) GS.5 53 19 35.8% 1 +[Q218H,D253G,T478R,P521S]-[G252V,T478K] GS.5 53 1 1.9% 1 +[H146K,R190S,Q218H,D253G,T478R,P521S]-[H146Q,G252V,T478K] GS.5 53 1 1.9% 1 +[L179F,R190S,Q218H,D253G,T478R,P521S]-[G252V,T478K] GS.5 53 1 1.9% 2 +[H146K,R190S,Q218H,D253G,T478R,P521S]-[H146Q,G252V,T478K,F490S] XBB.1.5.81 53 28 52.8% 0 +[T478R]-[T478K] (consensus) XBB.1.5.81 53 4 7.5% 1 +[H245Y,T478R]-[T478K] XBB.1.5.81 53 2 3.8% 1 +[T478R,V608I]-[T478K] XBB.1.5.81 53 2 3.8% 2 +[F186S,T478R,S1242I]-[T478K] XBB.1.5.81 53 1 1.9% 1 +[H146K,T478R]-[H146Q,T478K] AY.3.2 53 23 43.4% 0 +[T19R,E156G,F157-,R158-,T259I,L452R,P681R,A942T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.3.2 53 8 15.1% 1 +[T19R,E156G,F157-,R158-,T259I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.2 53 7 13.2% 1 +[T19R,E156G,F157-,R158-,T259I,L452R,P681R,A942T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.2 53 5 9.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A942T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.2 53 2 3.8% 1 +[L5F,T19R,E156G,F157-,R158-,T259I,L452R,P681R,A942T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.445 53 50 94.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.445 53 3 5.7% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.8 53 34 64.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.8 53 2 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P812S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.8 53 2 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] BA.4.8 53 2 3.8% 2 +[V3G,H69-,V70-,G75V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.8 53 2 3.8% 3 +[H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N679K,P681H] B.1.1.43 53 49 92.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.43 53 1 1.9% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.43 53 1 1.9% 1 +[C1236F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.43 53 1 1.9% 1 +[D178N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.43 53 1 1.9% 1 +[C1253F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XCA 53 47 88.7% 0 +[D111N,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486V,T678I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] (consensus) XCA 53 1 1.9% 1 +[D111N,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486V,A626V,T678I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] XCA 53 1 1.9% 1 +[D111N,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486V,E583Q,T678I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] XCA 53 1 1.9% 1 +[H69Y,D111N,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486V,T678I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] XCA 53 1 1.9% 1 +[D111N,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486V,T678I,V1065A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] BQ.1.1.73 53 44 83.0% 0 +[H69-,V70-,K147E,H207R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.73 53 5 9.4% 2 +[H69F,V70-,S71-,K147E,H207R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.73 53 1 1.9% 1 +[H69-,V70-,K147E,H207R,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.73 53 1 1.9% 1 +[H69-,V70-,K147E,H207R,V213G,G339D,K444T,L452R,N481S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.73 53 1 1.9% 1 +[H69-,V70-,K147E,H207R,V213G,G339D,K444T,L452R,F486V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.23 53 51 96.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.23 53 1 1.9% 1 +[I128F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.23 53 1 1.9% 1 +[G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GJ.1.2.7 53 32 60.4% 0 +[K182N,D253G,T478R,P521S]-[G252V,T478K] (consensus) GJ.1.2.7 53 7 13.2% 1 +[K182N,D253G,T478R,P521S,Q677H]-[G252V,T478K] GJ.1.2.7 53 2 3.8% 2 +[K182N,D253G,T478R,P521S,Q677H,P1162S]-[G252V,T478K] GJ.1.2.7 53 2 3.8% 2 +[K182N,D253G,T478R,P521S,Q677H,T1117I]-[G252V,T478K] GJ.1.2.7 53 2 3.8% 1 +[K182N,D253G,T478R,P521S,D1041E]-[G252V,T478K] FL.2.3.1 53 20 37.7% 0 +[K356T] (consensus) FL.2.3.1 53 4 7.5% 1 +[K356T,F490P]-[F490S] FL.2.3.1 53 4 7.5% 1 +[L5F,K356T] FL.2.3.1 53 4 7.5% 3 +[H49Y,V159I,K356T,P812S] FL.2.3.1 53 3 5.7% 2 +[K356T,T478R,T523I]-[T478K] FK.1.3 53 42 79.2% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.3 53 7 13.2% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,A623V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.3 53 1 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,T588I,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.3 53 1 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,N460K,F486P,F490S] FK.1.3 53 1 1.9% 1 +[I101T,K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.177 52 40 76.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.177 52 10 19.2% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.177 52 1 1.9% 2 +[L5F,T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.177 52 1 1.9% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.3 52 12 23.1% 0 +[L141-,G142-,V143-,A243-,L244-,Y265C,E484K,E1092K,H1101Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) P.3 52 8 15.4% 3 +[L141-,G142-,V143-,E484K,E1092K,H1101Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] P.3 52 3 5.8% 6 +[E484K,E1092K,H1101Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] P.3 52 3 5.8% 2 +[P9L,L141-,G142-,V143-,A243-,L244-,Y265C,E484K,E1092K,H1101Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] P.3 52 3 5.8% 2 +[L141-,G142-,V143-,Y265C,E484K,E1092K,H1101Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.264 52 33 63.5% 0 +[H146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.264 52 14 26.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.264 52 1 1.9% 1 +[H146Y,A706V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.264 52 1 1.9% 2 +[Q414E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.264 52 1 1.9% 2 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CP.6 52 28 53.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,E554Q,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.6 52 10 19.2% 3 +[H69-,V70-,N185I,F186-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.6 52 6 11.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.6 52 3 5.8% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.6 52 1 1.9% 2 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] JN.1.24.1 52 21 40.4% 0 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.24.1 52 11 21.2% 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,A288T,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.24.1 52 7 13.5% 1 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.24.1 52 4 7.7% 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.24.1 52 3 5.8% 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] BQ.1.1.74 52 25 48.1% 0 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.74 52 5 9.6% 1 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.74 52 4 7.7% 1 +[H69-,V70-,S112A,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.74 52 3 5.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.74 52 2 3.8% 1 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,F486V,P1263T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FG.1 52 38 73.1% 0 +[T284I,R403K,L513F] (consensus) FG.1 52 6 11.5% 1 +[T284I,R403K,L513F,S803T] FG.1 52 2 3.8% 1 +[T284I,R403K,L513F]-[K417N] FG.1 52 1 1.9% 1 +[T284I,R403K,L513F]-[R408S] FG.1 52 1 1.9% 2 +[R403K,L513F,I584V] B.1.1.378 51 36 70.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.378 51 12 23.5% 1 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.378 51 1 2.0% 3 +[T76I,N354S,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.378 51 1 2.0% 2 +[F565L,T1077I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.378 51 1 2.0% 2 +[R78S,D627H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.1 51 40 78.4% 0 +[D253G,F486S,N764R]-[G252V,F486P,N764K] (consensus) XBB.2.1 51 3 5.9% 1 +[D253G,F486S,N764R]-[G252V,K417N,F486P,N764K] XBB.2.1 51 1 2.0% 1 +[D253G,F486S,N764R]-[G252V,L368I,F486P,N764K] XBB.2.1 51 1 2.0% 1 +[D253G,F486S,N764R,A879T]-[G252V,F486P,N764K] XBB.2.1 51 1 2.0% 1 +[D253G,F486S,N764R,H1101Y]-[G252V,F486P,N764K] B.1.177.59 51 41 80.4% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.59 51 5 9.8% 1 +[L18F,Q52L,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.59 51 3 5.9% 1 +[L18F,R102I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.59 51 1 2.0% 1 +[L18F,T208M,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.59 51 1 2.0% 1 +[L18F,P26S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.275 51 34 66.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.275 51 15 29.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.275 51 1 2.0% 1 +[D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.275 51 1 2.0% 2 +[L5F,P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.431 51 50 98.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.431 51 1 2.0% 3 +[P26L,A222V,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.32.1 51 32 62.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.32.1 51 9 17.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,G72W,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.32.1 51 4 7.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.32.1 51 1 2.0% 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.32.1 51 1 2.0% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] B.1.438.4 51 47 92.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.438.4 51 1 2.0% 1 +[P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.4 51 1 2.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.4 51 1 2.0% 2 +[S659L,T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.4 51 1 2.0% 1 +[I1172V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GD.2 51 28 54.9% 0 +[L212S,F486S]-[F486P] (consensus) GD.2 51 9 17.6% 1 +[L212S,F486S]-[G142D,F486P] GD.2 51 3 5.9% 2 +[L212S,F486S]-[R408S,S477N,F486P] GD.2 51 2 3.9% 1 +[L212S,F486S,T678I]-[F486P] GD.2 51 2 3.9% 2 +[L212S,F486S]-[R408S,K417N,F486P] B.57 51 50 98.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.57 51 1 2.0% 1 +[P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AZ.6 51 49 96.1% 0 +[T95I,E484K,D796H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AZ.6 51 2 3.9% 1 +[T95I,L141F,E484K,D796H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XAD 50 43 86.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAD 50 2 4.0% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] XAD 50 1 2.0% 1 +[V213G,G339D,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAD 50 1 2.0% 2 +[V213G,G339D,T345S,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] XAD 50 1 2.0% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,D405N,V445P,G446S,N460K,F486P,F490S] B.1.1.375 50 26 52.0% 0 +[S689R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.375 50 3 6.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.375 50 3 6.0% 1 +[G181A,S689R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.375 50 3 6.0% 1 +[S689R,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.375 50 2 4.0% 1 +[T76I,S689R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.331 50 48 96.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.331 50 2 4.0% 1 +[R847T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.2 50 42 84.0% 0 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.438.2 50 8 16.0% 1 +[D80Y,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.9.3 50 22 44.0% 0 +[F486S]-[F486P] (consensus) XBB.1.9.3 50 2 4.0% 2 +[M153I,F486S]-[H146Q,F486P] XBB.1.9.3 50 2 4.0% 1 +[S255F,F486S]-[F486P] XBB.1.9.3 50 2 4.0% 1 +[N148T,F486S]-[F486P] XBB.1.9.3 50 2 4.0% 1 +[R190S,F486S]-[F486P] JN.2.3 50 36 72.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.2.3 50 2 4.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] JN.2.3 50 2 4.0% 3 +[+16MPLF,R21T,L24S,P25T,P26Q,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.3 50 2 4.0% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.3 50 1 2.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.214 50 33 66.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.214 50 3 6.0% 1 +[T1116N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214 50 2 4.0% 1 +[V705F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214 50 1 2.0% 7 +[+214TDR,A411T,L611R,A713V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214 50 1 2.0% 9 +[V171A,+214TDR,Q218H,A411T,L611R,A713V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBC.2 50 23 46.0% 0 +[P25S,K97R,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,F486L,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] (consensus) XBC.2 50 18 36.0% 1 +[P25S,K97R,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.2 50 2 4.0% 2 +[P25S,F59S,K97R,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,F486L,N703I,L763F]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F486P,F490S] XBC.2 50 1 2.0% 2 +[P25S,N87K,K97R,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.2 50 1 2.0% 3 +[P25S,F59S,K97R,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,N703I,L763F]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] B.1.14 50 48 96.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.14 50 2 4.0% 1 +[A288S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.17 50 48 96.0% 0 +[A831V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.17 50 1 2.0% 1 +[E132Q,A831V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.17 50 1 2.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HK.9 50 22 44.0% 0 +[Q52H,R190K,F456L] (consensus) HK.9 50 11 22.0% 1 +[Q52H,R190K,F456L,S494P] HK.9 50 7 14.0% 2 +[Q52H,R190K,F456L,S494P,I1227M] HK.9 50 3 6.0% 1 +[Q52H,R190K,F456L,A1020S] HK.9 50 2 4.0% 1 +[Q52H,R190K,F456L,A831V] GA.6 50 20 40.0% 0 +[D215H] (consensus) GA.6 50 11 22.0% 1 +[D215H,P251S] GA.6 50 3 6.0% 1 +[D215H,L216F] GA.6 50 3 6.0% 1 +[G184V,D215H] GA.6 50 3 6.0% 1 +[D215H,T250I] FL.1.6 50 25 50.0% 0 +[N481K,A701V,Q1208H] (consensus) FL.1.6 50 17 34.0% 1 +[N481K,N540D,A701V,Q1208H] FL.1.6 50 2 4.0% 1 +[N481K,A701V,A890V,Q1208H] FL.1.6 50 1 2.0% 1 +[N481K,S494P,A701V,Q1208H] FL.1.6 50 1 2.0% 1 +[N481K,A701V,Q1208H]-[K417N] B.1.450 50 45 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.450 50 1 2.0% 1 +[S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.450 50 1 2.0% 1 +[T678I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.450 50 1 2.0% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.450 50 1 2.0% 1 +[V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAR 50 18 36.0% 0 +[R78S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAR 50 17 34.0% 1 +[R78S,V213G,D215G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAR 50 13 26.0% 2 +[R78S,V213G,G339D,Q493R,Q675H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAR 50 2 4.0% 1 +[R78S,V213G,G339D,Q493R,V963I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.569 49 36 73.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.569 49 13 26.5% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.20 49 46 93.9% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.20 49 1 2.0% 1 +[H69-,V70-,N439K,Y1209H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.20 49 1 2.0% 1 +[H69-,V70-,F220V,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.20 49 1 2.0% 1 +[H69-,V70-,N439K,M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AN.1 49 41 83.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AN.1 49 4 8.2% 1 +[T547K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AN.1 49 1 2.0% 1 +[G446V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AN.1 49 1 2.0% 1 +[C1043S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AN.1 49 1 2.0% 1 -[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.579 49 25 51.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.579 49 20 40.8% 1 +[Q787R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.579 49 2 4.1% 2 +[A623V,Q787R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.579 49 1 2.0% 2 +[Q787R,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.579 49 1 2.0% 1 +[R246S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.6 49 41 83.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.6 49 3 6.1% 2 +[A27T,M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.6 49 3 6.1% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.6 49 1 2.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.6 49 1 2.0% 4 +[P9L,Y144C,L452R,N955H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.435 49 49 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) CM.5.1 49 36 73.5% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,Q675R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.5.1 49 4 8.2% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D,Q675R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.5.1 49 4 8.2% 2 +[M153T,N164K,L212S,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D,Q675R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.5.1 49 2 4.1% 2 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,Q675R,N679R,A684V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S,N679K] CM.5.1 49 1 2.0% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,Q675R,Q949R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BQ.1.1.16 49 41 83.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q607H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.16 49 4 8.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q607H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,V445P,G446S,F486P,F490S] BQ.1.1.16 49 1 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q607H,Q675R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.16 49 1 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P499S,Q607H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.16 49 1 2.0% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q607H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EG.4.2 49 36 73.5% 0 +[A623V] (consensus) EG.4.2 49 3 6.1% 1 +[A623V,S704L] EG.4.2 49 2 4.1% 1 +[A623V,T883I] EG.4.2 49 2 4.1% 1 +[V62L,A623V] EG.4.2 49 1 2.0% 1 +[A623V,A1087S] XCE 49 40 81.6% 0 +[Y200C] (consensus) XCE 49 2 4.1% 1 +[Y200C,S940F] XCE 49 1 2.0% 1 +[Y200C,Q836L] XCE 49 1 2.0% 1 +[Y200C]-[K417N] XCE 49 1 2.0% 2 +[Y200C,T478I,T572I]-[T478K] B.1.169 49 34 69.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.169 49 5 10.2% 1 +[T604I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.169 49 1 2.0% 2 +[Q183P,M902L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.169 49 1 2.0% 1 +[V1177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.169 49 1 2.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XBB.2.6.3 49 41 83.7% 0 +[D253G,F486S,T883I]-[G252V,F486P] (consensus) XBB.2.6.3 49 2 4.1% 1 +[H146K,D253G,F486S,T883I]-[H146Q,G252V,F486P] XBB.2.6.3 49 2 4.1% 1 +[P217H,D253G,F486S,T883I]-[G252V,F486P] XBB.2.6.3 49 1 2.0% 1 +[S221L,D253G,F486S,T883I]-[G252V,F486P] XBB.2.6.3 49 1 2.0% 1 +[D253G,F486S,T883I]-[Q183E,G252V,F486P] B.1.1.123 49 49 100.0% 0 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.419 49 48 98.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.419 49 1 2.0% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.25 48 34 70.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.25 48 2 4.2% 2 +[H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.25 48 2 4.2% 1 +[E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.25 48 2 4.2% 1 +[K558N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.25 48 2 4.2% 3 +[V367F,Q677H,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.130 48 31 64.6% 0 +[T19R,T95I,E156G,F157-,R158-,Y248S,S255F,I434V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.130 48 9 18.8% 1 +[T19R,T95I,E156G,F157-,R158-,Y248S,S255F,I434V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.130 48 3 6.2% 1 +[T19R,T95I,E156G,F157-,R158-,Y248S,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.130 48 2 4.2% 2 +[T19R,T95I,E156G,F157-,R158-,Y248S,S255F,I434V,L452R,P681R,G798S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.130 48 2 4.2% 1 +[T19R,T95I,E156G,F157-,R158-,Y248S,S255F,I434V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.25.1 48 31 64.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.25.1 48 6 12.5% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] BA.2.25.1 48 3 6.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.25.1 48 1 2.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.25.1 48 1 2.1% 1 +[V213G,G339D,Q493R,D1184G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.617.3 48 17 35.4% 0 +[T19R,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.617.3 48 4 8.3% 2 +[T19R,E156G,F157-,R158-,L452R,E484Q,P681R,D950N,E1072K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.3 48 4 8.3% 1 +[T19R,E156G,F157-,R158-,L452R,E484Q,P681R,D950N,E1072K]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.3 48 3 6.2% 1 +[T19R,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.3 48 2 4.2% 3 +[T19R,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.343 48 38 79.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.343 48 2 4.2% 3 +[S254F,F486L,A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.343 48 1 2.1% 2 +[S254F,A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.343 48 1 2.1% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.343 48 1 2.1% 2 -[T19I,L24-,P25-,P26-,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.1.7 48 26 54.2% 0 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.1.7 48 7 14.6% 4 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.7 48 3 6.2% 1 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] JN.1.1.7 48 2 4.2% 1 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.1.7 48 1 2.1% 5 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] AH.2 48 47 97.9% 0 +[V3G,L5F,L841F,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AH.2 48 1 2.1% 1 +[V3G,L5F,L841F,T859I,I1225V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596.1 48 29 60.4% 0 +[T73I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.596.1 48 15 31.2% 2 +[T73I,T572I,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596.1 48 1 2.1% 1 +[T73I,T618I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596.1 48 1 2.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596.1 48 1 2.1% 1 +[T73I,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.20 48 36 75.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.20 48 5 10.4% 2 +[P426S,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.20 48 1 2.1% 1 +[D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.20 48 1 2.1% 1 +[G181V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.20 48 1 2.1% 1 +[D1199H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GT.1 48 47 97.9% 0 +[P25S,I105V,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) GT.1 48 1 2.1% 1 +[P25S,I105V,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,Y1047F]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBB.8.2 48 30 62.5% 0 +[P521T]-[G252V] (consensus) XBB.8.2 48 8 16.7% 2 +[T51I]-[G252V] XBB.8.2 48 3 6.2% 1 +[Y269H,P521T]-[G252V] XBB.8.2 48 2 4.2% 1 +[L5F,P521T]-[G252V] XBB.8.2 48 2 4.2% 1 -[G252V] CK.1.1.1 48 24 50.0% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,E654K,N856S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1.1.1 48 6 12.5% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,L517I,E654K,N856S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.1.1 48 4 8.3% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,L517I,E654K,N856S,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.1.1 48 3 6.2% 1 +[H69-,V70-,L176F,V213G,G339D,K444N,L452R,F486V,E654K,N856S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.1.1 48 2 4.2% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,T572I,E654K,N856S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CH.1.1.23 48 39 81.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,T323K,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.23 48 1 2.1% 2 +[K97E,H146Y,K147E,W152R,F157L,I210V,V213G,G257S,T323K,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.23 48 1 2.1% 1 +[I100T,K147E,W152R,F157L,I210V,V213G,G257S,T323K,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.23 48 1 2.1% 1 +[K147E,W152R,F157L,E180G,I210V,V213G,G257S,T323K,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.23 48 1 2.1% 1 +[K147E,W152R,F157L,F186L,I210V,V213G,G257S,T323K,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.604 47 36 76.6% 0 +[H49Y,A262S,L452R,Q613H,P681R,N978S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] (consensus) B.1.604 47 2 4.3% 1 +[H49Y,A262S,L452R,Q613H,P681R,N978S,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.604 47 2 4.3% 2 +[H49Y,A262S,L452R,Q613H,P681R,N978S,G1251V,S1252C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.604 47 1 2.1% 2 +[H49Y,A243-,L244-,A262S,L452R,Q613H,P681R,N978S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.604 47 1 2.1% 1 +[H49Y,S98F,A262S,L452R,Q613H,P681R,N978S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.160.21 47 43 91.5% 0 +[V622A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.21 47 2 4.3% 1 +[V622A,D1165G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.21 47 1 2.1% 2 +[V143D,V622A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.21 47 1 2.1% 1 +[V622A,A653V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.467 47 42 89.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.467 47 2 4.3% 1 +[G1167D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.467 47 2 4.3% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.467 47 1 2.1% 1 +[D1168G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.32.1 47 42 89.4% 0 +[V6L,F456L,E554Q] (consensus) FL.32.1 47 1 2.1% 1 +[V6L,F456L,E554Q]-[T19I] FL.32.1 47 1 2.1% 2 +[V6L,F456L,E554Q]-[K417N,P681H] FL.32.1 47 1 2.1% 1 +[V6F,F456L,E554Q] FL.32.1 47 1 2.1% 1 +[V6L,F456L,E554Q,S1170F] B.1.1.371 47 35 74.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.371 47 4 8.5% 1 +[A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.371 47 2 4.3% 3 +[T572N,Q690R,D1260N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.371 47 2 4.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.371 47 2 4.3% 2 +[Q690R,D1260N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.119 47 45 95.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.119 47 1 2.1% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.119 47 1 2.1% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.56 47 34 72.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.56 47 2 4.3% 1 +[E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.56 47 1 2.1% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.56 47 1 2.1% 1 +[G181E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.56 47 1 2.1% 1 +[Q920L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.3.4 47 36 76.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.4 47 7 14.9% 1 +[V83I,K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.4 47 1 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.4 47 1 2.1% 6 +[V83I,I210V,V213G,G257S,K356T,V445A,K535R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.4 47 1 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A,D1084Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBB.1.5.74 47 36 76.6% 0 +[K462R] (consensus) XBB.1.5.74 47 5 10.6% 2 +[Y200C] XBB.1.5.74 47 1 2.1% 1 +[P209S,K462R] XBB.1.5.74 47 1 2.1% 1 +[L54F,K462R] XBB.1.5.74 47 1 2.1% 1 +[K462R]-[Q183E] B.1.485 47 47 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.520 46 35 76.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.520 46 3 6.5% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.520 46 1 2.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.520 46 1 2.2% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.520 46 1 2.2% 1 +[C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.334 46 38 82.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.334 46 3 6.5% 1 +[P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.334 46 2 4.3% 1 +[A871V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.334 46 1 2.2% 1 +[+521P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.334 46 1 2.2% 1 +[C1254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.500 46 40 87.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.500 46 3 6.5% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.500 46 2 4.3% 1 +[A688S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.500 46 1 2.2% 1 +[A1070V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.16.24 46 19 41.3% 0 +[E180V,K182E,T478R,V551I,E554K]-[T478K] (consensus) XBB.1.16.24 46 5 10.9% 2 +[H146K,E180V,K182E,R346A,T478R,V551I,E554K]-[H146Q,R346T,T478K] XBB.1.16.24 46 3 6.5% 1 +[N148T,E180V,K182E,T478R,V551I,E554K]-[T478K] XBB.1.16.24 46 2 4.3% 1 +[E180V,K182E,D215N,T478R,V551I,E554K]-[T478K] XBB.1.16.24 46 2 4.3% 2 +[Q14R,E180V,K182E,T478R,V551I,E554K,A623T]-[T478K] B.1.1.367 46 37 80.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.367 46 4 8.7% 2 +[A222V,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.367 46 2 4.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.367 46 1 2.2% 2 +[N641I,V642-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.367 46 1 2.2% 4 +[D215G,R346I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] S.1 46 40 87.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) S.1 46 3 6.5% 1 +[T778I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] S.1 46 3 6.5% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.39 46 26 56.5% 0 +[A222V,S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.39 46 18 39.1% 1 +[A222V,S256L,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.39 46 1 2.2% 1 +[I128V,A222V,S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.39 46 1 2.2% 1 +[A222V,L229F,S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.129 46 33 71.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.129 46 3 6.5% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.129 46 3 6.5% 1 +[V1177L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.129 46 1 2.2% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.129 46 1 2.2% 15 +[T19K,Q52K,G75V,G142V,D215G,P251T,G257D,R346K,N450D,E484K,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.578 46 32 69.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.578 46 4 8.7% 1 +[M731I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.578 46 4 8.7% 2 +[M731I,I1227T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.578 46 1 2.2% 1 +[A1080S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.578 46 1 2.2% 1 +[H245Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.432 46 33 71.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.432 46 5 10.9% 1 +[T76I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.432 46 3 6.5% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.432 46 2 4.3% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.432 46 2 4.3% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.326 46 34 73.9% 0 +[E554D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.326 46 9 19.6% 1 +[G75R,E554D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.326 46 1 2.2% 2 +[G75R,E554D,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.326 46 1 2.2% 1 +[E554D,S929I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.326 46 1 2.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.283 46 22 47.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.283 46 17 37.0% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.283 46 2 4.3% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.283 46 2 4.3% 1 +[A1020D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.283 46 1 2.2% 1 +[V6F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BG.6 46 34 73.9% 0 +[V213G,G339D,L452Q,Q493R,S704L,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] (consensus) BG.6 46 4 8.7% 2 +[G181V,V213G,G339D,L452Q,Q493R,S704L,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.6 46 4 8.7% 1 +[V213G,G339D,L452Q,Q493R,S704L,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.6 46 1 2.2% 3 +[V213G,G339D,S371L,L452Q,Q493R,S704L,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,G446S,N460K,F486P,F490S] BG.6 46 1 2.2% 5 +[V213G,G339D,S371L,Q493R,S704L,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XBB.2.10 46 29 63.0% 0 +[Q52H,D253G,F486S]-[G252V,F486P] (consensus) XBB.2.10 46 2 4.3% 1 +[Q52H,F486S]-[G252V,F486P] XBB.2.10 46 2 4.3% 2 +[Q52H,F486S]-[G252V,R408S,F486P] XBB.2.10 46 2 4.3% 1 +[Q52H,H146K,D253G,F486S]-[H146Q,G252V,F486P] XBB.2.10 46 1 2.2% 1 +[Q52H,D253G,F486S,Q1113L]-[G252V,F486P] XBB.1.35 46 29 63.0% 0 +[F486S]-[F486P] (consensus) XBB.1.35 46 4 8.7% 1 XBB.1.35 46 2 4.3% 3 +[G482-,E619K] XBB.1.35 46 1 2.2% 1 +[N148T,F486S]-[F486P] XBB.1.35 46 1 2.2% 1 +[F486S]-[S375F,F486P] B.1.1.40 46 35 76.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.40 46 2 4.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.40 46 2 4.3% 1 +[G261V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.40 46 1 2.2% 2 +[P330S,K786R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.40 46 1 2.2% 1 +[T676A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.234 46 38 82.6% 0 +[M153I,S691A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.234 46 2 4.3% 1 +[M153I,S691A,D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.234 46 2 4.3% 1 +[R102G,M153I,S691A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.234 46 1 2.2% 1 +[M153I,R683L,S691A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.234 46 1 2.2% 1 +[M153I,S691A,K1205N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.242 46 43 93.5% 0 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.242 46 3 6.5% 1 +[P26T,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.515 46 40 87.0% 0 +[T22N,S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.515 46 3 6.5% 1 +[S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.515 46 1 2.2% 2 +[T22N,H245Y,S254F,S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.515 46 1 2.2% 1 +[T22N,S698L,R765L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.515 46 1 2.2% 1 +[T22N,H245Y,S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GJ.1.2.4 46 28 60.9% 0 +[K182N,D253G,S255F,P521S]-[G252V] (consensus) GJ.1.2.4 46 10 21.7% 1 +[K182N,D253G,S255F,T478R,P521S]-[G252V,T478K] GJ.1.2.4 46 4 8.7% 2 +[H146K,K182N,D253G,S255F,T478R,P521S]-[H146Q,G252V,T478K] GJ.1.2.4 46 1 2.2% 1 +[H146K,K182N,D253G,S255F,P521S]-[H146Q,G252V] GJ.1.2.4 46 1 2.2% 3 +[K182N,D253G,S255F,L455-,+456S,T478R,P521S]-[G252V,T478K] GQ.1 46 36 78.3% 0 +[K147E,W152R,F157L,I210V,V213G,+254P,G257-,K444T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] (consensus) GQ.1 46 2 4.3% 1 +[K147E,W152R,F157L,I210V,V213G,+254P,G257-,K444M,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] GQ.1 46 1 2.2% 1 +[K147E,W152R,F157L,I210V,V213G,+254P,G257-,K444T,L452R,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] GQ.1 46 1 2.2% 1 +[K147E,W152R,F157L,I210V,V213G,+254P,G257-,K444T,L452R,Q675K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] GQ.1 46 1 2.2% 1 +[H146Y,K147E,W152R,F157L,I210V,V213G,+254P,G257-,K444T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] FP.2.1 46 34 73.9% 0 +[F186S,T478R]-[T478K] (consensus) FP.2.1 46 4 8.7% 1 +[T76I,F186S,T478R]-[T478K] FP.2.1 46 1 2.2% 3 +[F186S,A262S,V433I,T478R]-[G142D,T478K] FP.2.1 46 1 2.2% 1 +[T478R]-[T478K] FP.2.1 46 1 2.2% 1 +[H146K,F186S,T478R]-[H146Q,T478K] B.1.258.15 45 33 73.3% 0 +[M177I,N439K,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.15 45 11 24.4% 1 +[N439K,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.15 45 1 2.2% 1 +[M177I,N439K,S1175P,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.188 45 35 77.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.188 45 5 11.1% 1 +[G946V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.188 45 1 2.2% 1 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.188 45 1 2.2% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.188 45 1 2.2% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.267 45 25 55.6% 0 +[C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.267 45 14 31.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.267 45 3 6.7% 1 +[M740I,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.267 45 1 2.2% 1 +[N501S,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.267 45 1 2.2% 1 +[Q314H,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.3.1 45 33 73.3% 0 +[F486S,Q677R]-[G252V,F486P] (consensus) XBB.3.1 45 4 8.9% 1 +[F486S,Q677R]-[T19I,G252V,F486P] XBB.3.1 45 1 2.2% 1 +[E484T,F486S,Q677R]-[G252V,E484A,F486P] XBB.3.1 45 1 2.2% 2 +[F486S,Q677R,D839Y,N1187D]-[G252V,F486P] XBB.3.1 45 1 2.2% 1 +[F486S,E619Q,Q677R]-[G252V,F486P] B.1.161 45 44 97.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.161 45 1 2.2% 1 +[K1045N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GK.3 45 27 60.0% 0 +[L455F,F456L] (consensus) GK.3 45 6 13.3% 1 +[L5F,L455F,F456L] GK.3 45 3 6.7% 1 +[L455F,F456L,T572I] GK.3 45 2 4.4% 1 +[L455F,F456L,G1124V] GK.3 45 2 4.4% 1 +[L455F,F456L,Q675H] BQ.1.1.50 45 37 82.2% 0 +[H69-,V70-,I210-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.50 45 4 8.9% 1 +[L5F,H69-,V70-,I210-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.50 45 2 4.4% 1 +[H69-,V70-,I210-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.50 45 1 2.2% 1 +[H69-,V70-,I210-,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] BQ.1.1.50 45 1 2.2% 2 +[L5F,H69-,V70-,I210-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] B.1.1.522 44 44 100.0% 0 +[D138N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AY.39.3 44 26 59.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.3 44 9 20.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,V483F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.3 44 2 4.5% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,V483F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.3 44 2 4.5% 1 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.3 44 1 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.5 44 43 97.7% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AA.5 44 1 2.3% 1 +[A222V,Q414K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.169 44 35 79.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.169 44 3 6.8% 1 +[A1070V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.169 44 2 4.5% 1 +[A701S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.169 44 2 4.5% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.169 44 1 2.3% 1 +[R1091L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.181 44 25 56.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.181 44 11 25.0% 3 +[R78G,D80Y,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.181 44 5 11.4% 2 +[D80Y,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.181 44 1 2.3% 2 +[K77N,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.181 44 1 2.3% 2 +[S940F,M1229T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CA.2 44 35 79.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S494P,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CA.2 44 1 2.3% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,F486S,S494P,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.2 44 1 2.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S494P,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,Y505H] CA.2 44 1 2.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S494P,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P,F490S] CA.2 44 1 2.3% 5 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S494P,D1199N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.536 44 35 79.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.536 44 7 15.9% 1 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.536 44 1 2.3% 1 +[L303F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.536 44 1 2.3% 1 +[A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.379 44 38 86.4% 0 +[R214L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.379 44 4 9.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.379 44 2 4.5% 1 +[T95I,R214L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.83 44 27 61.4% 0 (consensus) XBB.1.5.83 44 4 9.1% 1 +[H146K]-[H146Q] XBB.1.5.83 44 3 6.8% 1 +[D843N] XBB.1.5.83 44 2 4.5% 2 +[F186S,T478R]-[T478K] XBB.1.5.83 44 2 4.5% 1 -[Y144-] B.1.593 44 44 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) GW.5.1 44 13 29.5% 0 +[L455F,F456L,T478I,E554K]-[T478K] (consensus) GW.5.1 44 6 13.6% 1 +[D215H,L455F,F456L,T478I,E554K]-[T478K] GW.5.1 44 5 11.4% 2 +[G184V,L455F,F456L,T478I,E554K,A852S]-[T478K] GW.5.1 44 5 11.4% 1 +[L455F,F456L,T478I,E554K]-[R408S,T478K] GW.5.1 44 4 9.1% 1 +[V227L,L455F,F456L,T478I,E554K]-[T478K] B.27 44 42 95.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.27 44 1 2.3% 1 +[R214L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.27 44 1 2.3% 1 +[I934M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.51 44 30 68.2% 0 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.51 44 3 6.8% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] BA.5.2.51 44 1 2.3% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.51 44 1 2.3% 6 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V,N657Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.51 44 1 2.3% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,V483A,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BR.4 43 27 62.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BR.4 43 3 7.0% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,S673R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.4 43 2 4.7% 3 +[K147E,W152R,F157L,K182R,I210V,V213G,G257S,K444T,L452R,S673R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BR.4 43 1 2.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,Q580H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,F486P,F490S] BR.4 43 1 2.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] B.1.1.404 43 21 48.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.404 43 2 4.7% 10 +[H69-,V70-,P85S,E96G,D215G,A243-,L244-,L452R,S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.404 43 2 4.7% 1 +[D88Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.404 43 2 4.7% 1 +[Y248S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.404 43 2 4.7% 11 +[H69-,V70-,P85S,E96G,D215G,A243-,L244-,L452R,S940F]-[L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] C.31 43 31 72.1% 0 +[S98F,E309Q,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.31 43 8 18.6% 3 +[A27V,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.31 43 3 7.0% 2 +[K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.31 43 1 2.3% 1 +[A67S,S98F,E309Q,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.547 43 35 81.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.547 43 4 9.3% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.547 43 1 2.3% 2 +[T29I,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.547 43 1 2.3% 1 +[P174S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.547 43 1 2.3% 1 +[A1070V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.1 43 31 72.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.1 43 9 20.9% 1 +[V1128I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.1 43 1 2.3% 2 +[A522S,V1128I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.1 43 1 2.3% 1 +[V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.1 43 1 2.3% 2 +[S939F,V1128I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.555 43 35 81.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.555 43 2 4.7% 1 +[I834T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.555 43 2 4.7% 1 +[E554V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.555 43 2 4.7% 2 +[I834T,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.555 43 1 2.3% 1 +[G1085E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428.3 43 38 88.4% 0 +[N481K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.428.3 43 4 9.3% 1 +[N481K,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428.3 43 1 2.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.18.1 43 13 30.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.18.1 43 7 16.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,N556K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.18.1 43 7 16.3% 10 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.18.1 43 4 9.3% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,N556K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.18.1 43 2 4.7% 6 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.1.466 42 34 81.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.466 42 4 9.5% 2 +[D936Y,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.466 42 3 7.1% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.466 42 1 2.4% 2 +[A1020S,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XCK 42 18 42.9% 0 +[F456L,T478R,A701V]-[T478K] (consensus) XCK 42 14 33.3% 1 +[D178N,F456L,T478R,A701V]-[T478K] XCK 42 4 9.5% 1 +[F157L,F456L,T478R,A701V]-[T478K] XCK 42 3 7.1% 2 +[D178N,R214L,F456L,T478R,A701V]-[T478K] XCK 42 1 2.4% 1 +[F456L,T478R,A701V]-[G142D,T478K] CM.7 42 24 57.1% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.7 42 4 9.5% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.7 42 4 9.5% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,E340D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.7 42 2 4.8% 2 +[K150E,M153T,N164K,V213G,H245N,G257D,G339D,K444S,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.7 42 2 4.8% 1 +[M153T,N164K,V213G,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] B.1.205 42 36 85.7% 0 +[I119V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.205 42 2 4.8% 1 +[I119V,A852S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.205 42 1 2.4% 1 +[I119V,V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.205 42 1 2.4% 2 +[I119V,Y508H,I1216T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.205 42 1 2.4% 1 +[I119V,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBC.1.2.1 42 17 40.5% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.2.1 42 12 28.6% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I,A845S]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.2.1 42 3 7.1% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.2.1 42 2 4.8% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K] XBC.1.2.1 42 1 2.4% 3 +[L18F,P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N460I,N703I,A845S]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] CM.9 42 22 52.4% 0 +[H69-,V70-,M153T,N164K,V213G,H245N,S256L,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.9 42 9 21.4% 2 +[M153T,N164K,V213G,H245N,S256L,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.9 42 9 21.4% 3 +[M153T,N164K,V213G,H245N,S256L,G257D,V267L,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.9 42 1 2.4% 3 +[M153T,N164K,V213G,H245N,S256L,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,E484A,F486P,F490S] CM.9 42 1 2.4% 3 +[M153T,N164K,V213G,H245N,S256L,G257D,G339D,K444R,N450D,L452M,E484R,F490L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BQ.1.1.34 42 38 90.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.34 42 2 4.8% 1 +[H69-,V70-,V213G,G339D,A344T,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.34 42 1 2.4% 1 +[H69-,V70-,V83F,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.34 42 1 2.4% 1 +[H69-,V70-,V213G,L216F,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.1.16.2 42 17 40.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.16.2 42 11 26.2% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16.2 42 2 4.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,G842D,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16.2 42 2 4.8% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.16.2 42 2 4.8% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,G842D,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BQ.1.26.2 42 38 90.5% 0 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.26.2 42 2 4.8% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.26.2 42 1 2.4% 2 +[T19L,H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.26.2 42 1 2.4% 1 +[H69-,V70-,F157L,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBB.1.36 42 30 71.4% 0 +[F486S,F490P]-[F486P,F490S] (consensus) XBB.1.36 42 3 7.1% 1 +[F486S,F490P]-[V83A,F486P,F490S] XBB.1.36 42 2 4.8% 2 +[F486S,F490P]-[R408S,F486P,F490S,D796Y] XBB.1.36 42 2 4.8% 1 +[F486S,F490P,E619K]-[F486P,F490S] XBB.1.36 42 1 2.4% 9 +[H69-,V70-,V213G,F486S,F490P,D1260Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,F486P,F490S] XBB.1.14 42 21 50.0% 0 +[G75V,F486S,E554K]-[F486P] (consensus) XBB.1.14 42 2 4.8% 1 +[G75V,F486S,E554K]-[L368I,F486P] XBB.1.14 42 2 4.8% 1 +[G75V,F486S,E554K]-[Y144-,F486P] XBB.1.14 42 2 4.8% 1 +[G75V,F486S,E554K,P621L]-[F486P] XBB.1.14 42 2 4.8% 1 +[G75V,F486S,E554K,S704L]-[F486P] AA.6 42 36 85.7% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AA.6 42 3 7.1% 1 +[A222V,I1013T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.6 42 2 4.8% 1 +[A222V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.6 42 1 2.4% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AS.2 42 41 97.6% 0 +[A522S,Q675R,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AS.2 42 1 2.4% 1 +[H146Y,A522S,Q675R,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.7 42 39 92.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.7 42 2 4.8% 1 +[T1100I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.7 42 1 2.4% 1 +[K187N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.2.6 42 14 33.3% 0 +[T259S,E554A,N641K] (consensus) FL.2.6 42 5 11.9% 2 +[N641K] FL.2.6 42 4 9.5% 3 +[E471Q,N641K] FL.2.6 42 4 9.5% 5 +[E484S,N641K,P809T,T883I]-[E484A] FL.2.6 42 2 4.8% 3 +[N641K,P809T] EG.1.1 42 34 81.0% 0 +[V70F,I312V,Q613H] (consensus) EG.1.1 42 4 9.5% 1 +[V70F,I312V,Q613H,T732I] EG.1.1 42 1 2.4% 1 +[V70F,I312V,Q613H,L1224F] EG.1.1 42 1 2.4% 1 +[V70F,Q613H] EG.1.1 42 1 2.4% 1 +[V70F,E96V,I312V,Q613H] B.1.76 42 34 81.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.76 42 7 16.7% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.76 42 1 2.4% 1 +[A831V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.46 41 40 97.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.46 41 1 2.4% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.498 41 38 92.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.498 41 1 2.4% 1 +[V171F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.498 41 1 2.4% 1 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.498 41 1 2.4% 1 +[S151I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BM.1.1.5 41 34 82.9% 0 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.1.1.5 41 1 2.4% 1 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,A292T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.5 41 1 2.4% 2 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,T323I,L452R,F486S,L517F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.5 41 1 2.4% 1 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,T323I,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.5 41 1 2.4% 1 +[H69Q,K147E,W152R,F157L,N185S,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BN.2.1 41 28 68.3% 0 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] (consensus) BN.2.1 41 6 14.6% 2 +[H49Y,V62L,K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.2.1 41 3 7.3% 3 +[H49Y,V62L,K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.2.1 41 1 2.4% 3 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.2.1 41 1 2.4% 1 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,K356T,T1117I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] B.1.1.172 41 41 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XDU 41 36 87.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDU 41 2 4.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDU 41 1 2.4% 15 +[N17M,+17P,+18FNFI,R21-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481S,G482-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDU 41 1 2.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDU 41 1 2.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBB.1.38 41 15 36.6% 0 +[F486S,T732I]-[F486P] (consensus) XBB.1.38 41 10 24.4% 1 +[F486S,Q690R,T732I]-[F486P] XBB.1.38 41 1 2.4% 1 +[N125K,F486S,T732I]-[F486P] XBB.1.38 41 1 2.4% 2 +[F486S,Q690R,T732I]-[R346T,F486P] XBB.1.38 41 1 2.4% 3 +[T259I,F486S,E554K,T732I]-[H146Q,F486P] BN.1.8 41 28 68.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A475V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.8 41 9 22.0% 1 +[K147E,W152R,F157L,R190M,I210V,V213G,G257S,K356T,A475V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.8 41 1 2.4% 3 +[K147E,W152R,F157L,R190M,I210V,V213G,G257S,K356T,A475V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,Y505H] BN.1.8 41 1 2.4% 2 +[K147E,W152R,F157L,R190M,I210V,V213G,R214H,G257S,K356T,A475V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.8 41 1 2.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A475V,G482R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BQ.1.1.64 41 21 51.2% 0 +[H69-,V70-,F186S,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.64 41 4 9.8% 1 +[H69-,V70-,F186S,V213G,G339D,K444T,L452R,T478Q,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] BQ.1.1.64 41 3 7.3% 1 +[H69-,V70-,G72E,F186S,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.64 41 3 7.3% 1 +[H69-,V70-,F186S,V213G,P251L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.64 41 3 7.3% 2 +[H69-,V70-,F186S,V213G,G339D,K444T,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBF.10 41 32 78.0% 0 +[K147E,W152R,M153I,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.10 41 2 4.9% 1 +[K147E,W152R,M153I,F157L,I210V,V213G,G257S,E406Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.10 41 1 2.4% 1 +[K147E,W152R,M153I,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,N460K] XBF.10 41 1 2.4% 1 +[K147E,W152R,M153I,F157L,I210V,V213G,G257S,Q836R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.10 41 1 2.4% 2 +[K147E,W152R,M153I,F157L,I210V,V213G,G257S,R646H,D1084V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CM.2.1 41 18 43.9% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.2.1 41 8 19.5% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.2.1 41 3 7.3% 3 +[M153T,N164K,N211-,L212I,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.2.1 41 1 2.4% 2 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,E484A,F486P,F490S] CM.2.1 41 1 2.4% 2 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,V551F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] B.1.369.1 41 41 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) GY.3 41 28 68.3% 0 +[M177I,E180V,T478R]-[T478K] (consensus) GY.3 41 2 4.9% 1 +[M177I,E180V,T250A,T478R]-[T478K] GY.3 41 2 4.9% 1 +[M177I,E180V,T478R,R1107S]-[T478K] GY.3 41 1 2.4% 2 +[N148T,M177I,E180V,T259I,T478R]-[T478K] GY.3 41 1 2.4% 1 +[M177I,E180V,T478R]-[K417N,T478K] XBF.7.1 41 38 92.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,T323I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.7.1 41 1 2.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T323I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P] XBF.7.1 41 1 2.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T323I,R683W]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.7.1 41 1 2.4% 6 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,T323I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S] EU.1 41 12 29.3% 0 +[P521S]-[R408S,S477N] (consensus) EU.1 41 10 24.4% 2 +[P521S] EU.1 41 5 12.2% 1 +[P521S]-[R408S,S477N,Q954H] EU.1 41 3 7.3% 1 +[P521S]-[V83A,R408S,S477N] EU.1 41 2 4.9% 3 +[P521S,E619Q] B.1.251 41 39 95.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.251 41 1 2.4% 1 +[E1262G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.251 41 1 2.4% 1 +[L1200F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HL.2 41 23 56.1% 0 +[Q613H,S929N] (consensus) HL.2 41 3 7.3% 2 +[R346I,Q613H,E619K,S929N]-[R346T] HL.2 41 3 7.3% 1 +[Q613H,S929N,H1058Y] HL.2 41 2 4.9% 2 +[T259S,Q613H,S929N,A1078S] HL.2 41 1 2.4% 1 +[Q613H,S929N]-[T19I] JN.1.27 41 33 80.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.27 41 3 7.3% 7 +[R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.27 41 2 4.9% 8 +[R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,N481K,E484K,E554K,A570V,P621S,P681R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.27 41 1 2.4% 1 +[+16MPLF,R21T,T33A,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.27 41 1 2.4% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,H146-,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.53 41 29 70.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.53 41 4 9.8% 1 +[T676P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.53 41 3 7.3% 1 +[I1232L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.53 41 2 4.9% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.53 41 1 2.4% 1 +[S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.96 41 37 90.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.96 41 1 2.4% 1 +[P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.96 41 1 2.4% 1 +[T547I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.96 41 1 2.4% 1 +[R346K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.96 41 1 2.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.240.1 40 28 70.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.240.1 40 12 30.0% 1 +[A829S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.485 40 21 52.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.485 40 9 22.5% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.485 40 3 7.5% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.485 40 2 5.0% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.485 40 1 2.5% 1 +[V143F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.409 40 37 92.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.409 40 1 2.5% 1 +[G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.409 40 1 2.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.409 40 1 2.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.639 40 18 45.0% 0 +[H69-,V70-,M153T,+214QAS,E484K,T859N,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.639 40 7 17.5% 5 +[H69-,V70-,M153T,+214QAS,R246N,S247-,Y248-,E484K,A520S,Q677R,T859N,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.639 40 4 10.0% 1 +[H69-,V70-,M153T,+214QAS,E484K,T859N,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.639 40 4 10.0% 6 +[N30K,H69-,V70-,M153T,+214QAS,R246N,S247-,Y248-,E484K,A520S,Q677R,T859N,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.639 40 2 5.0% 1 +[H69-,V70-,M153T,+214QAS,E484K,T859N,D936Y,G1046S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.302 40 35 87.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.302 40 4 10.0% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.302 40 1 2.5% 2 +[A222V,L229F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.21 40 24 60.0% 0 +[F486A]-[F486P] (consensus) XBB.1.21 40 3 7.5% 1 +[F486A]-[R346T,F486P] XBB.1.21 40 3 7.5% 2 +[H146K,T259I,F486A]-[H146Q,F486P] XBB.1.21 40 2 5.0% 1 +[N481K,F486A]-[F486P] XBB.1.21 40 1 2.5% 1 +[F486A,V1096I]-[F486P] XBB.2.7 40 12 30.0% 0 +[D253G,F486S]-[G252V,F486P] (consensus) XBB.2.7 40 8 20.0% 1 +[W152R,D253G,F486S]-[G252V,F486P] XBB.2.7 40 5 12.5% 1 +[D253G,F486S,E748V]-[G252V,F486P] XBB.2.7 40 2 5.0% 2 +[D253G,F486S,E748V]-[V83A,G252V,F486P] XBB.2.7 40 2 5.0% 1 +[D253G,F486S,A684V]-[G252V,F486P] XBB.1.44 40 15 37.5% 0 +[Y453F,F486S,T747I]-[F486P] (consensus) XBB.1.44 40 10 25.0% 1 +[F486S,T747I]-[F486P] XBB.1.44 40 3 7.5% 1 +[Y453F,F486S,T747I,V1104I]-[F486P] XBB.1.44 40 3 7.5% 2 +[F486S,T747I]-[Q183E,F486P] XBB.1.44 40 2 5.0% 2 +[F486S,S680F,T747I]-[F486P] FW.2 40 29 72.5% 0 +[K356T,R403K,F486S]-[F486P] (consensus) FW.2 40 2 5.0% 1 +[H146K,K356T,R403K,F486S]-[H146Q,F486P] FW.2 40 1 2.5% 1 +[E340Q,K356T,R403K,F486S]-[F486P] FW.2 40 1 2.5% 1 +[K356T,R403K,F486S,E583D]-[F486P] FW.2 40 1 2.5% 1 +[K356T,R403K,F486S,Q677H]-[F486P] XBB.1.5.42 40 15 37.5% 0 +[E281D,V445S]-[V445P] (consensus) XBB.1.5.42 40 12 30.0% 1 +[E281D] XBB.1.5.42 40 2 5.0% 1 +[E281D,V445S,A701T]-[V445P] XBB.1.5.42 40 2 5.0% 1 +[E281D,V445S]-[K417N,V445P] XBB.1.5.42 40 2 5.0% 2 +[L5F,E281D] B.1.225 40 36 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.225 40 1 2.5% 1 +[A829T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.225 40 1 2.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.225 40 1 2.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.225 40 1 2.5% 1 +[S221W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GK.3.2 40 28 70.0% 0 +[L455F,F456L,T572I] (consensus) GK.3.2 40 5 12.5% 1 +[N185Y,L455F,F456L,T572I] GK.3.2 40 2 5.0% 1 +[L455F,F456L,T572I,V860A] GK.3.2 40 1 2.5% 1 +[L455F,F456L,T572I,I714L] GK.3.2 40 1 2.5% 3 +[L455F,F456L,T572I]-[N440K,V445P,G446S] GC.2 40 32 80.0% 0 +[A352S] (consensus) GC.2 40 4 10.0% 1 +[A352S,T478R]-[T478K] GC.2 40 2 5.0% 2 +[H146K,A352S,L938F]-[H146Q] GC.2 40 1 2.5% 1 +[A352S,Q1201K] GC.2 40 1 2.5% 1 +[A352S,N679R]-[N679K] B.1.247 40 18 45.0% 0 +[R78M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.247 40 12 30.0% 2 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.247 40 8 20.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.247 40 1 2.5% 3 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.247 40 1 2.5% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.18.2 40 23 57.5% 0 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.18.2 40 4 10.0% 1 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.18.2 40 4 10.0% 4 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.18.2 40 1 2.5% 1 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] JN.1.18.2 40 1 2.5% 5 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H] B.1.1.310 39 37 94.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.310 39 2 5.1% 1 +[M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XA 39 38 97.4% 0 +[H69-,V70-,T549I,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) XA 39 1 2.6% 1 +[H69-,V70-,T549I,A570D,T716I,S982A,D1118H]-[L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.393 39 21 53.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.393 39 4 10.3% 2 +[H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.393 39 2 5.1% 2 +[T385I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.393 39 2 5.1% 4 +[H69-,V70-,N439K,V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.393 39 1 2.6% 3 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.621.2 39 26 66.7% 0 +[T95I,+143T,Y144S,Y145N,R346K,Y449N,E484K,E583D,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.621.2 39 3 7.7% 1 +[T95I,+143T,Y144S,Y145N,R346K,Y449N,E484K,T572I,E583D,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621.2 39 2 5.1% 1 +[T95I,+143T,Y144S,Y145N,R346K,Y449N,E484K,E583D,D950N,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621.2 39 1 2.6% 1 +[T95I,+143T,Y144S,Y145N,R346K,Y449N,E484K,E583D,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621.2 39 1 2.6% 1 +[T95I,+143T,Y144S,Y145N,R346K,Y449N,E484K,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] GJ.1.2.3 39 33 84.6% 0 +[T76I,K182N,D253G,P521S]-[G252V] (consensus) GJ.1.2.3 39 2 5.1% 1 +[T76I,K182N,D253G,P521S,I1225V]-[G252V] GJ.1.2.3 39 1 2.6% 1 +[T76I,K182N,D253G,P521S]-[Y144-,G252V] GJ.1.2.3 39 1 2.6% 1 +[A67V,T76I,K182N,D253G,P521S]-[G252V] GJ.1.2.3 39 1 2.6% 1 +[T76I,K182N,D253G,P521S,Q675E]-[G252V] B.1.22.1 39 37 94.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.22.1 39 1 2.6% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.22.1 39 1 2.6% 1 +[V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.341 39 35 89.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.341 39 2 5.1% 1 +[P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.341 39 1 2.6% 1 +[I1210T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.341 39 1 2.6% 1 +[N658Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.139 39 35 89.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.139 39 2 5.1% 1 +[N658K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.139 39 1 2.6% 1 +[D198Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.139 39 1 2.6% 2 +[R408T,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.40 39 37 94.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.40 39 1 2.6% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.40 39 1 2.6% 1 +[D228Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.1 39 15 38.5% 0 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.1 39 13 33.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.214.1 39 4 10.3% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.1 39 2 5.1% 2 +[A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.214.1 39 2 5.1% 2 +[L938I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CU.1 39 33 84.6% 0 +[H69-,V70-,T95I,V213G,G339D,L452R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CU.1 39 4 10.3% 1 +[H69-,V70-,T95I,V213G,G339D,L452R,F486V,T547K,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CU.1 39 1 2.6% 1 +[H69-,V70-,T95I,V213G,G339D,L452R,F486V,T547K,I834V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CU.1 39 1 2.6% 2 +[H69-,V70-,T95I,V213G,G339D,L452R,F486V,T547K]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] EG.9.1 39 25 64.1% 0 +[A344T,R403K] (consensus) EG.9.1 39 8 20.5% 2 +[A344T,R403K,S494P,S929T] EG.9.1 39 4 10.3% 1 +[A344T,R403K,S494P] EG.9.1 39 2 5.1% 3 +[A344T,R403K,S494P,N703S,S929T] XBB.3.4 39 7 17.9% 0 +[T76I,H146K,F486S,E990D]-[H146Q,G252V,F486P] XBB.3.4 39 6 15.4% 4 +[K182E,E990D]-[G252V] XBB.3.4 39 4 10.3% 3 +[R273K,F486S,E990D]-[G252V,F486P] XBB.3.4 39 3 7.7% 2 +[F486S,E990D]-[G252V,F486P] (consensus) XBB.3.4 39 2 5.1% 4 +[R273K,F486S,E619Q,E990D]-[G252V,F486P] B.1.1.136 39 29 74.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.136 39 8 20.5% 1 +[Q493K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.136 39 2 5.1% 1 +[R21T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBJ.4 39 37 94.9% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) XBJ.4 39 1 2.6% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D,H625Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ.4 39 1 2.6% 2 +[M153T,N164K,V213G,H245N,G261D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] B.1.153 39 33 84.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.153 39 4 10.3% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.153 39 1 2.6% 16 +[P25S,F106I,F168S,F559I,A672S,V722D,M731L,P812T,I870T,K921E,D950E,E1031K,S1037L,V1128L,M1237K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.153 39 1 2.6% 2 +[D138H,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.436 39 39 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.284 39 29 74.4% 0 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.284 39 8 20.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.284 39 1 2.6% 2 -[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.284 39 1 2.6% 2 +[F490L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.13 38 36 94.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.13 38 1 2.6% 1 +[G232A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.13 38 1 2.6% 1 +[W152L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.13 38 26 68.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.13 38 5 13.2% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.13 38 2 5.3% 1 +[Q314R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.13 38 1 2.6% 2 +[F1095L,K1266R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.13 38 1 2.6% 1 +[V1040F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.42.1 38 12 31.6% 0 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.42.1 38 10 26.3% 1 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.42.1 38 4 10.5% 2 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.42.1 38 3 7.9% 2 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.42.1 38 1 2.6% 2 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.352 38 12 31.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.352 38 11 28.9% 1 +[L560Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.352 38 3 7.9% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.352 38 3 7.9% 1 +[G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.352 38 2 5.3% 1 +[A688S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KV.1 38 25 65.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KV.1 38 3 7.9% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KV.1 38 2 5.3% 6 +[R21T,S50L,H69-,V70-,V127F,Y144H,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KV.1 38 2 5.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,T768I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KV.1 38 1 2.6% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBB.2.3.10 38 27 71.1% 0 +[D253G,P521S]-[G252V] (consensus) XBB.2.3.10 38 3 7.9% 1 +[H146K,D253G,P521S]-[H146Q,G252V] XBB.2.3.10 38 1 2.6% 1 +[D253G,P521S]-[G252V,R408S] XBB.2.3.10 38 1 2.6% 3 +[D253G,P521S]-[G252V,N440K,V445P,G446S] XBB.2.3.10 38 1 2.6% 22 +[D253G,I312V]-[L24-,P25-,P26-,A27S,V83A,Y144-,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N679K,P681H,N764K,Q954H] B.1.1.325 38 18 47.4% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.325 38 5 13.2% 2 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.325 38 4 10.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.325 38 3 7.9% 2 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.325 38 2 5.3% 2 +[Q414K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.8 38 37 97.4% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AA.8 38 1 2.6% 1 +[A222V,I693F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.9 38 25 65.8% 0 +[H69-,V70-,S151I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.9 38 5 13.2% 2 +[H69-,V70-,S151I,V213G,G339D,K444T,L452R,F486V,S929I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.9 38 4 10.5% 1 +[H69-,V70-,S151I,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.9 38 1 2.6% 1 +[H69-,V70-,I128V,S151I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.9 38 1 2.6% 6 +[H69-,V70-,T109A,S151I,F157L,V213G,G339D,K444T,L452R,F486A]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] B.1.460 38 35 92.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.460 38 1 2.6% 1 +[H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.460 38 1 2.6% 2 +[D215H,E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.460 38 1 2.6% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.2 38 37 97.4% 0 +[A771S,P1263T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.2 38 1 2.6% 1 +[P1263T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FK.1.3.1 38 38 100.0% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,E583D,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) B.1.38 38 38 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) JN.13 38 31 81.6% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.13 38 2 5.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,G1251V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.13 38 1 2.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1200F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.13 38 1 2.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1227V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.13 38 1 2.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BL.1.1 38 33 86.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,D614S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,D614G] (consensus) BL.1.1 38 1 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,D614S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S,D614G] BL.1.1 38 1 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,S494P,D574V,D614S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,D614G] BL.1.1 38 1 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,D614S,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,D614G] BL.1.1 38 1 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T547I,D574V,D614S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,D614G] B.1.256 38 32 84.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.256 38 3 7.9% 1 +[N354S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.256 38 2 5.3% 1 +[D808N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.256 38 1 2.6% 1 +[T573N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.3 37 14 37.8% 0 +[L141-,G142-,V143-,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2.5.3 37 5 13.5% 4 +[L141-,G142-,V143-,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.3 37 2 5.4% 7 +[L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.3 37 2 5.4% 2 +[L141-,G142-,V143-,D215A,+215AGY,L452R,V622F,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5.3 37 1 2.7% 1 +[L141-,G142-,V143-,D215A,+215AGY,L452R,A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.338 37 35 94.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.338 37 1 2.7% 1 +[S704L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.338 37 1 2.7% 1 +[V952I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.384 37 37 100.0% 0 +[V367F,P479S,K854N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.2.11 37 13 35.1% 0 +[D253G,F486S]-[G252V,F486P] XBB.2.11 37 11 29.7% 2 +[Y248H,D253G,F486S,T732I]-[G252V,F486P] (consensus) XBB.2.11 37 5 13.5% 3 +[Y248H,D253G,F486S,K529N,T732I]-[G252V,F486P] XBB.2.11 37 3 8.1% 3 +[Y248H,D253G,F486S,T732I,A1087S]-[G252V,F486P] XBB.2.11 37 1 2.7% 1 +[D111N,D253G,F486S]-[G252V,F486P] B.1.400.1 37 29 78.4% 0 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.400.1 37 6 16.2% 1 +[E484K,I1130M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.400.1 37 1 2.7% 1 +[S12F,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.400.1 37 1 2.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.268 37 30 81.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.268 37 5 13.5% 2 +[S12F,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.268 37 1 2.7% 1 +[D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.268 37 1 2.7% 1 +[D287V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DJ.1.3 37 28 75.7% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) DJ.1.3 37 5 13.5% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DJ.1.3 37 1 2.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DJ.1.3 37 1 2.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,Y505H] DJ.1.3 37 1 2.7% 2 +[H69-,V70-,R78K,K147E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBB.1.37 37 23 62.2% 0 +[F486S]-[F486P] (consensus) XBB.1.37 37 2 5.4% 1 +[F486S]-[G252V,F486P] XBB.1.37 37 2 5.4% 1 +[F486S]-[G142D,F486P] XBB.1.37 37 1 2.7% 2 +[L5F,F486S]-[K417N,F486P] XBB.1.37 37 1 2.7% 1 +[H146K,F486S]-[H146Q,F486P] XBS 37 33 89.2% 0 +[K147E,W152R,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) XBS 37 2 5.4% 1 +[Q14R,K147E,W152R,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBS 37 1 2.7% 1 +[K147E,W152R,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBS 37 1 2.7% 1 +[K147E,W152R,F157L,V213G,G339D,K444T,L452R,P479L,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FL.4.4 37 24 64.9% 0 -[T478K] (consensus) FL.4.4 37 2 5.4% 1 -[G142D,T478K] FL.4.4 37 2 5.4% 1 -[K417N,T478K] FL.4.4 37 2 5.4% 1 +[Q675H]-[T478K] FL.4.4 37 1 2.7% 3 +[K150N,G339D,F456L]-[G339H,T478K] XBB.1.34.1 37 14 37.8% 0 +[E554K,P681R]-[P681H] (consensus) XBB.1.34.1 37 7 18.9% 2 +[K182I,D215G,E554K,P681R]-[P681H] XBB.1.34.1 37 3 8.1% 1 +[K182I,E554K,P681R]-[P681H] XBB.1.34.1 37 3 8.1% 1 +[E554K,P681R,A1020S]-[P681H] XBB.1.34.1 37 1 2.7% 3 +[G181E,F456L,E554K,P681R,S939F]-[P681H] B.38 36 30 83.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.38 36 4 11.1% 1 +[A831V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.38 36 1 2.8% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.38 36 1 2.8% 3 +[D215H,E484D,S686G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.93 36 33 91.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.93 36 1 2.8% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.93 36 1 2.8% 1 +[E773G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.93 36 1 2.8% 1 +[E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GN.5 36 27 75.0% 0 (consensus) GN.5 36 1 2.8% 1 +[F186L] GN.5 36 1 2.8% 2 +[E583D,A1070T] GN.5 36 1 2.8% 1 +[D1165H] GN.5 36 1 2.8% 1 +[L216F] KP.4.1 36 30 83.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KP.4.1 36 1 2.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D796H,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,D796Y] KP.4.1 36 1 2.8% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,P337S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A831V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.4.1 36 1 2.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.4.1 36 1 2.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.2.1 36 16 44.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.2.1 36 15 41.7% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.2.1 36 2 5.6% 2 +[+16MPLF,R21T,S50L,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1101Y,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.2.1 36 1 2.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.2.1 36 1 2.8% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] CM.8 36 23 63.9% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] (consensus) CM.8 36 4 11.1% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478E,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,T478K,E484A,F486P,F490S] CM.8 36 3 8.3% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8 36 1 2.8% 1 +[M153T,N164K,V213G,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8 36 1 2.8% 1 +[M153T,N164K,L212S,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] B.1.1.407 36 31 86.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.407 36 2 5.6% 1 +[I1216V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.407 36 1 2.8% 1 +[K356R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.407 36 1 2.8% 1 +[A653V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.407 36 1 2.8% 1 +[A520V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.163 36 21 58.3% 0 +[I1172V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.163 36 13 36.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.163 36 1 2.8% 3 +[L54F]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.163 36 1 2.8% 2 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.31 36 27 75.0% 0 +[Y453F,T478R,F486S]-[T478K,F486P] (consensus) XBB.1.31 36 1 2.8% 2 +[T323I,Y453F,T478R,F486S]-[K417N,T478K,F486P] XBB.1.31 36 1 2.8% 3 +[H146K,Y453F,T478R,F486S,T632N,H1101Y]-[H146Q,T478K,F486P] XBB.1.31 36 1 2.8% 3 +[W152L,T250I,Y453F,T478R,F486S,V510I]-[T478K,F486P] XBB.1.31 36 1 2.8% 3 +[G184D,Y453F,T478R,F486S,K529N,Q677H]-[T478K,F486P] B.6.1 36 28 77.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6.1 36 6 16.7% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.1 36 1 2.8% 1 +[V6F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.1 36 1 2.8% 1 +[Y28F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FZ.1 36 27 75.0% 0 +[E583D] (consensus) FZ.1 36 8 22.2% 1 +[E583D,T678I] FZ.1 36 1 2.8% 1 +[E583D,L858I] GS.2 36 32 88.9% 0 +[D253G,T470N,T478R,P521S]-[G252V,T478K] (consensus) GS.2 36 1 2.8% 1 +[D253G,T470N,T478R,P521S,N1187S]-[G252V,T478K] GS.2 36 1 2.8% 12 +[E132D,D253G]-[G252V,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H] GS.2 36 1 2.8% 1 +[D253G,T299I,T470N,T478R,P521S]-[G252V,T478K] GS.2 36 1 2.8% 1 +[D253G,T470N,T478R,P521S,T572I]-[G252V,T478K] FP.2.1.1 36 27 75.0% 0 +[F186S,L452Q,T478R]-[T478K] (consensus) FP.2.1.1 36 4 11.1% 1 +[F186S,L452Q,T478R,E583D]-[T478K] FP.2.1.1 36 1 2.8% 1 +[F186S,L452Q,T478R]-[T19I,T478K] FP.2.1.1 36 1 2.8% 1 +[F186S,V289I,L452Q,T478R]-[T478K] FP.2.1.1 36 1 2.8% 2 +[H146K,F186S,L452Q,T478R,D936Y]-[H146Q,T478K] B.1.143 36 31 86.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.143 36 1 2.8% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.143 36 1 2.8% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.143 36 1 2.8% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.143 36 1 2.8% 1 +[N148Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.75.8 36 31 86.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75.8 36 3 8.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452Q,G842S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.8 36 2 5.6% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,L452Q,L455S,A626V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] B.1.1.524 36 11 30.6% 0 +[P9L,L141-,G142-,V143-,N439K,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.524 36 9 25.0% 1 +[P9L,C136F,L141-,G142-,V143-,N439K,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.524 36 4 11.1% 4 +[P9L,C136F,N439K,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.524 36 4 11.1% 3 +[P9L,N439K,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.524 36 1 2.8% 6 +[P9L,C136F,S373L,N439K,T859N,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.13 36 19 52.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.13 36 5 13.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.13 36 2 5.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.13 36 2 5.6% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.13 36 2 5.6% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.332 35 25 71.4% 0 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.332 35 2 5.7% 4 +[L18F,T20N,P26S,A684T,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.332 35 2 5.7% 1 +[D1163Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.332 35 1 2.9% 1 +[S256P,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.332 35 1 2.9% 1 +[S98F,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] K.1 35 33 94.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) K.1 35 1 2.9% 1 +[A771V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] K.1 35 1 2.9% 1 +[A688S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.3 35 17 48.6% 0 +[T638A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.595.3 35 6 17.1% 1 +[T638A,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.3 35 5 14.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.3 35 2 5.7% 4 +[T22I,T95A,S494P,T638A,D737Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595.3 35 1 2.9% 2 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.168 35 15 42.9% 0 +[M177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.168 35 10 28.6% 2 +[A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.168 35 5 14.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.168 35 3 8.6% 1 +[M177I,S813G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.168 35 1 2.9% 3 +[W152C,S982A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.28 35 27 77.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.28 35 2 5.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.28 35 2 5.7% 1 +[T76I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.28 35 1 2.9% 1 +[V193L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.28 35 1 2.9% 2 +[Q23R,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.20 35 35 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.28.1 35 16 45.7% 0 +[K356T,R403K,F486S]-[F486P] (consensus) XBB.1.28.1 35 8 22.9% 1 +[K356T,R403K] XBB.1.28.1 35 3 8.6% 1 +[K356T,R403K,F486S,N703S]-[F486P] XBB.1.28.1 35 1 2.9% 2 +[K356T,R403K,F486S,R567K,T572I]-[F486P] XBB.1.28.1 35 1 2.9% 1 +[K356T,R403K,F486S,A688V]-[F486P] FL.15.1 35 16 45.7% 0 +[L455F,F456L] (consensus) FL.15.1 35 8 22.9% 1 +[L455F,F456L,A475V] FL.15.1 35 3 8.6% 2 +[L455F,F456L,A475V]-[K417N] FL.15.1 35 1 2.9% 1 +[V3I,L455F,F456L] FL.15.1 35 1 2.9% 1 +[L455F,F456L,V1122L] B.1.277 35 27 77.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.277 35 7 20.0% 1 +[M177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.277 35 1 2.9% 2 +[M177I,A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.11 34 21 61.8% 0 +[F486S]-[F486P] (consensus) XBB.1.11 34 4 11.8% 1 +[L5F,F486S]-[F486P] XBB.1.11 34 1 2.9% 1 +[F486S,K529R]-[F486P] XBB.1.11 34 1 2.9% 1 +[T76I,F486S]-[F486P] XBB.1.11 34 1 2.9% 1 +[F486S,A846V]-[F486P] B.1.616 34 30 88.2% 0 +[H66D,G142V,D215G,V483A,G669S,Q949R,N1187D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.616 34 1 2.9% 1 +[H66D,G142V,D215G,V483A,G669S,Q949R,G1167D,N1187D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.616 34 1 2.9% 1 +[H66D,G142V,D215G,V483A,H625Q,G669S,Q949R,N1187D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.616 34 1 2.9% 1 +[H66D,G142V,D215G,V483A,G669S,A879S,Q949R,N1187D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.616 34 1 2.9% 1 +[H66D,G142V,V483A,G669S,Q949R,N1187D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.462 34 22 64.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.462 34 3 8.8% 2 +[Q779R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.462 34 2 5.9% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.462 34 1 2.9% 4 +[L141-,G142-,V143-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.462 34 1 2.9% 1 +[V635I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.562 34 20 58.8% 0 +[E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.562 34 9 26.5% 1 +[A653V,E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.562 34 2 5.9% 1 +[T29I,E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.562 34 2 5.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.562 34 1 2.9% 1 +[E654Q,A706S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.613 34 23 67.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.613 34 8 23.5% 1 +[T553S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.613 34 1 2.9% 1 +[A1070S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.613 34 1 2.9% 2 +[T553S,K795Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.613 34 1 2.9% 1 +[S1261F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BL.1.3 34 17 50.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F490L,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BL.1.3 34 4 11.8% 3 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,A1070T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BL.1.3 34 3 8.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.1.3 34 2 5.9% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,G446T,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] BL.1.3 34 2 5.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F490L,D574V,T638I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.5.2.45 34 29 85.3% 0 +[H69-,V70-,V213G,G339D,K444Q,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.45 34 2 5.9% 1 +[H69-,V70-,T73A,V213G,G339D,K444Q,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.45 34 1 2.9% 1 +[H69-,V70-,V213G,G339D,K444Q,L452R,F486V,V1189A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.45 34 1 2.9% 2 +[L5F,H69-,V70-,V213G,G339D,K444Q,L452R,F486V,S1261P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.45 34 1 2.9% 1 +[H69-,V70-,V213G,G339D,K444Q,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.173 34 25 73.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.173 34 7 20.6% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.173 34 2 5.9% 1 +[T76I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.103 34 33 97.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.103 34 1 2.9% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.29 34 19 55.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.29 34 6 17.6% 1 +[K147E,W152R,F157L,I210V,V213G,H245Y,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.29 34 4 11.8% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.29 34 2 5.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,P1263L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.29 34 1 2.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,I1216M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.4.1 34 28 82.4% 0 +[K147E,W152R,F157L,G181A,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.4.1 34 3 8.8% 1 +[K147E,W152R,F157L,G181A,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q493L,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.4.1 34 1 2.9% 1 +[K147E,W152R,F157L,G181A,I210V,V213G,D215G,G257S,K444T,L452R,F456L,F486S,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.4.1 34 1 2.9% 2 +[K147E,W152R,F157L,G181A,I210V,V213G,D215G,G257S,K304R,K444T,L452R,F486S,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,N460K,F486P,F490S] FK.1.4.1 34 1 2.9% 1 +[K147E,W152R,F157L,G181A,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,S704L,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FY.1.3 34 27 79.4% 0 +[Y200C,E583D] (consensus) FY.1.3 34 1 2.9% 1 +[Y200C,D215G,E583D] FY.1.3 34 1 2.9% 1 +[Y200C,E583D]-[G339H] FY.1.3 34 1 2.9% 1 +[Y200C,A260V,E583D] FY.1.3 34 1 2.9% 1 +[Y200C,W258R,E583D] B.1.1.208 34 31 91.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.208 34 1 2.9% 1 +[G219D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.208 34 1 2.9% 1 +[G669A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.208 34 1 2.9% 1 +[R246K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.27 34 22 64.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.27 34 12 35.3% 1 +[I834T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KP.2.2 33 21 63.6% 0 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KP.2.2 33 8 24.2% 4 +[R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2.2 33 1 3.0% 5 +[R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T778I,S939F,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2.2 33 1 3.0% 1 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1266R]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2.2 33 1 3.0% 1 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1078T,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.359 33 30 90.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.359 33 1 3.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.359 33 1 3.0% 1 +[Y1155H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.359 33 1 3.0% 1 +[Q1180H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.88 33 24 72.7% 0 +[A222V,A262S,P272L,E484K,T572I,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.88 33 4 12.1% 1 +[A222V,A262S,P272L,E484K,T572I,G594S,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.88 33 3 9.1% 1 +[A222V,A262S,P272L,E484K,T572I,L1063F,V1133I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.88 33 1 3.0% 1 +[A222V,A262S,P272L,T299I,E484K,T572I,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.88 33 1 3.0% 1 +[S50L,A222V,A262S,P272L,E484K,T572I,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XDS 33 15 45.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDS 33 3 9.1% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDS 33 3 9.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1092G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDS 33 2 6.1% 3 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,A672V,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDS 33 2 6.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.442 33 22 66.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.442 33 10 30.3% 1 +[R403K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.442 33 1 3.0% 2 +[R403K,A958S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.487 33 23 69.7% 0 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.487 33 8 24.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.487 33 1 3.0% 2 +[S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.487 33 1 3.0% 1 +[T307I,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBF.8.1 33 30 90.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.8.1 33 1 3.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,P621S,A1078S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.8.1 33 1 3.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,P621S,L1200F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.8.1 33 1 3.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T500A,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] FR.1.5 33 11 33.3% 0 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) FR.1.5 33 9 27.3% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,Q836K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.5 33 2 6.1% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,T588K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.5 33 2 6.1% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.5 33 1 3.0% 2 +[K147E,W152R,F157L,K187E,I210V,V213G,K356T,T588K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.2 33 29 87.9% 0 +[K147E,W152R,F157L,K187E,R190M,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) FR.1.2 33 1 3.0% 1 +[K147E,W152R,F157L,K187E,R190M,I210V,V213G,G257S,K356T,A1070V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.2 33 1 3.0% 1 +[K147E,W152R,F157L,K187E,R190M,I210V,V213G,G257S,K356T,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.2 33 1 3.0% 1 +[K147E,W152R,F157L,K187E,R190M,I210V,V213G,G257S,K356T,G1219V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FR.1.2 33 1 3.0% 1 +[K147E,W152R,F157L,K187E,R190M,I210V,V213G,G257S,K356T,T1006I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] CH.2 33 21 63.6% 0 +[K147E,W152R,F157L,Q183H,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.2 33 2 6.1% 4 +[K147E,W152R,F157L,Q183H,I210V,V213G,G257S,F486S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.2 33 1 3.0% 1 +[K147E,W152R,F157L,Q183H,I210V,V213G,G257S,F486S,L752F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.2 33 1 3.0% 1 +[K147E,W152R,F157L,Q183H,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.2 33 1 3.0% 1 +[K147E,W152R,F157L,Q183H,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,N460K,F486P,F490S] BN.1.6 33 26 78.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.6 33 3 9.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V615I,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.6 33 1 3.0% 1 +[V6A,K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.6 33 1 3.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.6 33 1 3.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,P621S,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.1.346 33 32 97.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.346 33 1 3.0% 2 +[D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] FL.26.1 32 24 75.0% 0 +[Q493L] (consensus) FL.26.1 32 5 15.6% 1 +[V70L,Q493L] FL.26.1 32 1 3.1% 3 +[Q493L,V503F]-[V83A,Y505H] FL.26.1 32 1 3.1% 2 +[Q493L]-[V83A,Y505H] FL.26.1 32 1 3.1% 1 +[G261D,Q493L] B.1.243.2 32 20 62.5% 0 +[R246-,S247-,Y248-,N501T,N751K,D936H,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.243.2 32 5 15.6% 1 +[R246-,S247-,Y248-,K444R,N501T,N751K,D936H,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.243.2 32 2 6.2% 2 +[R246-,S247-,Y248-,N501T,N751K,D936H,E1258D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.243.2 32 1 3.1% 2 +[R246-,S247-,Y248-,K444R,N501T,N751K,D936H,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.243.2 32 1 3.1% 1 +[V70I,R246-,S247-,Y248-,N501T,N751K,D936H,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.585 32 30 93.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.585 32 1 3.1% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.585 32 1 3.1% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.3.1 32 22 68.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.3.1 32 3 9.4% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3.1 32 2 6.2% 3 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,K206T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T573I,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3.1 32 2 6.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455F,N481K,V483-,E484K,E554K,A570V,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3.1 32 1 3.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,F486S,E554K,A570V,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] B.1.36.34 32 25 78.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.34 32 4 12.5% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.34 32 2 6.2% 1 +[R765L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.34 32 1 3.1% 1 +[K41R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.493 32 32 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) BN.4 32 19 59.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] (consensus) BN.4 32 3 9.4% 1 +[K147E,W152R,F157L,E180D,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.4 32 1 3.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V595I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.4 32 1 3.1% 2 +[K147E,W152R,F157L,E180D,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,F486P] BN.4 32 1 3.1% 4 +[I210V,V213G,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] KP.2.3 32 14 43.8% 0 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KP.2.3 32 10 31.2% 4 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2.3 32 2 6.2% 1 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2.3 32 1 3.1% 1 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,L118F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2.3 32 1 3.1% 1 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N280S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.40 32 6 18.8% 0 +[R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.40 32 5 15.6% 5 +[+16MPLF,R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.40 32 4 12.5% 1 +[R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.40 32 2 6.2% 7 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.40 32 2 6.2% 7 +[+16MPLF,R21T,S31P,S50L,F58Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1199H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BQ.1.1.14 32 29 90.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.14 32 2 6.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S940F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.14 32 1 3.1% 8 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,F486P,F490S] C.19 32 32 100.0% 0 +[D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) FP.2 32 8 25.0% 0 +[F186S] (consensus) FP.2 32 4 12.5% 1 +[F186S]-[T478K] FP.2 32 3 9.4% 6 +[F186S,V445A,I651V]-[H146Q,R346T,T376A,V445P,H655Y] FP.2 32 2 6.2% 1 +[F59L,F186S] FP.2 32 2 6.2% 1 +[F186S,T478R]-[T478K] B.1.1.507 32 23 71.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.507 32 3 9.4% 2 +[Q1208H,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.507 32 2 6.2% 1 +[M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.507 32 1 3.1% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.507 32 1 3.1% 3 +[A701V,Q1208H,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.2.5 32 22 68.8% 0 +[T478R,F490P,Q675H]-[T478K,F490S] (consensus) EG.2.5 32 5 15.6% 1 +[T478R,Q675H]-[T478K] EG.2.5 32 1 3.1% 1 +[T478R,F490P,Q675H,T1136I]-[T478K,F490S] EG.2.5 32 1 3.1% 2 +[T478R,Q613H,Q675H]-[T478K] EG.2.5 32 1 3.1% 1 +[T478R,F490P,Q675H,C1248F]-[T478K,F490S] HC.3 32 13 40.6% 0 +[K356T,T572I,P793S] (consensus) HC.3 32 12 37.5% 1 +[K356T,T572I,P793S,S975N] HC.3 32 3 9.4% 1 +[K356T,T572I,A688V,P793S] HC.3 32 2 6.2% 2 +[K356T,W436R,T572I,P793S,S975N] HC.3 32 1 3.1% 2 +[K356T,S494P,T572I,P621S,P793S] BM.4.1 32 11 34.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BM.4.1 32 8 25.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,N450D,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BM.4.1 32 5 15.6% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BM.4.1 32 2 6.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,T1006A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BM.4.1 32 1 3.1% 3 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,N450D,F486S,L752F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] DN.1.1.1 32 30 93.8% 0 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,Y453F,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.1.1.1 32 1 3.1% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,Y453F,F486V,N536K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1.1.1 32 1 3.1% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,Y453F,F486V,A706S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.387 32 32 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6.3 32 29 90.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6.3 32 1 3.1% 1 +[P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.3 32 1 3.1% 2 +[D215G,H1058Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.3 32 1 3.1% 1 +[D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.162 32 29 90.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.162 32 3 9.4% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.239 31 16 51.6% 0 +[L5F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.239 31 5 16.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.239 31 5 16.1% 2 +[V3G,L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.239 31 1 3.2% 1 +[L5F,E484K,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.239 31 1 3.2% 1 +[L5F,Q677H,A892G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.403 31 29 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.403 31 2 6.5% 2 +[S247I,M1050I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KP.2.1 31 22 71.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KP.2.1 31 2 6.5% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681-,+683W,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2.1 31 1 3.2% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K,G1251A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.2.1 31 1 3.2% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S373P,R408S,V445P,E484A,F490S,P681H] KP.2.1 31 1 3.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,I1114T,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.348 31 29 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.348 31 2 6.5% 1 +[P26L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.47.2 31 24 77.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.47.2 31 4 12.9% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47.2 31 1 3.2% 1 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47.2 31 1 3.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.47.2 31 1 3.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V171L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681-,+683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] FD.2.1 31 11 35.5% 0 +[H146K]-[H146Q] (consensus) FD.2.1 31 7 22.6% 1 +[H146K,D1163H]-[H146Q] FD.2.1 31 4 12.9% 1 +[H146K,F456L]-[H146Q] FD.2.1 31 3 9.7% 1 +[H146K,P809L]-[H146Q] FD.2.1 31 1 3.2% 1 +[H146K,A783S]-[H146Q] B.1.203 31 13 41.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.203 31 12 38.7% 1 +[N658D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.203 31 2 6.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.203 31 1 3.2% 1 +[P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.203 31 1 3.2% 2 +[L5F,N658D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GJ.1 31 15 48.4% 0 +[K182N,D253G,P521S]-[G252V] (consensus) GJ.1 31 2 6.5% 1 +[K182N,D253G,P521S]-[G252V,R408S] GJ.1 31 2 6.5% 1 +[K182N,D253G,P521S,I1221T]-[G252V] GJ.1 31 2 6.5% 1 +[K182N,D253G]-[G252V] GJ.1 31 1 3.2% 1 +[K182N,D253G,P521S,E554K]-[G252V] CP.3 31 27 87.1% 0 +[H69-,V70-,V213G,G339D,L452R,N460Y,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.3 31 1 3.2% 1 +[H69-,V70-,V213G,G339D,L452R,N460Y,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CP.3 31 1 3.2% 1 +[H69-,V70-,V213G,G339D,L452R,N460Y,F486V,S758I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.3 31 1 3.2% 1 +[H69-,V70-,V213G,G339D,L452R,N460Y,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] CP.3 31 1 3.2% 6 +[H69-,V70-,V213G,G339D,V350D,Y351-,L452R,N460Y,F486V,G1059S,P1263S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] XBB.1.10 31 15 48.4% 0 +[L5F,R403K,F486S,A852V]-[F486P] (consensus) XBB.1.10 31 3 9.7% 1 +[L5F,H146K,R403K,F486S,A852V]-[H146Q,F486P] XBB.1.10 31 2 6.5% 1 +[L5F,R403K,F486S,A852V]-[V83A,F486P] XBB.1.10 31 1 3.2% 3 +[L5F,T307I,R403K,F486S,A852V,K1181N]-[V83A,F486P] XBB.1.10 31 1 3.2% 2 +[L5F,R403K,F486S,A852V,I1114F]-[V83A,F486P] B.1.224 31 21 67.7% 0 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.224 31 4 12.9% 1 +[G639S,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.224 31 2 6.5% 2 +[A348V,A846V,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.224 31 2 6.5% 1 +[A348V,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.224 31 2 6.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HC.1 31 21 67.7% 0 +[Y145P,H146-,K356T,T572I,P631S]-[Y144-,H146Q] (consensus) HC.1 31 3 9.7% 1 +[Y145P,H146-,K356T,T572I,P631S,H1083Y]-[Y144-,H146Q] HC.1 31 2 6.5% 1 +[Y145P,H146-,K356T,T572I,P631S,A701V]-[Y144-,H146Q] HC.1 31 2 6.5% 1 +[Y145P,H146-,K356T,T572I,P631S]-[Y144-,H146Q,K417N] HC.1 31 1 3.2% 1 +[Y145P,H146-,K356T,T572I,P631S,D1163Y]-[Y144-,H146Q] XBB.1.13.1 31 16 51.6% 0 +[F486S,F490P,Q564E,N856K]-[F486P,F490S] (consensus) XBB.1.13.1 31 3 9.7% 1 +[F486S,F490P,Q564E,N856K]-[K417N,F486P,F490S] XBB.1.13.1 31 1 3.2% 3 +[F486S,F490P,Q564E,I670M,N856K]-[G142D,R408S,F486P,F490S] XBB.1.13.1 31 1 3.2% 3 +[L54F,F486S,F490P,Q564E,N856K]-[G142D,R408S,F486P,F490S] XBB.1.13.1 31 1 3.2% 1 +[L5F,F486S,F490P,Q564E,N856K]-[F486P,F490S] B.1.535 31 29 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.535 31 1 3.2% 1 +[D1139Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.535 31 1 3.2% 1 +[A626V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBF.1.1 31 27 87.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,P621S,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.1.1 31 4 12.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,P621S,M740I,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] B.1.640 31 12 38.7% 0 +[P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,I210T,R346S,N394S,Y449N,F490R,T859N,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.640 31 7 22.6% 1 +[P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,I210T,R346S,N394S,Y449N,F490R,T859N,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.640 31 1 3.2% 2 +[P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R346S,N394S,Y449N,F490R,T859N,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.640 31 1 3.2% 11 +[P9L,E96Q,R346S,N394S,Y449N,F490R,T859N,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.640 31 1 3.2% 15 +[P9L,E96Q,E156G,F157-,R158-,T240I,R346S,N394S,Y449N,F490R,T859N,D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.559 31 29 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.559 31 1 3.2% 1 +[G72W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.559 31 1 3.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.10.4 31 20 64.5% 0 +[W64R,L141-,G142-,V143-,V213G,A243-,L244-,G339D,S494P,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) BA.2.10.4 31 3 9.7% 10 +[W64R,V213G,G339D,S494P,P1143L]-[L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] BA.2.10.4 31 3 9.7% 10 +[W64R,V213G,G339D,S494P,P1143L]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] BA.2.10.4 31 3 9.7% 1 +[W64R,L141-,G142-,V143-,V213G,A243-,L244-,G339D,S494P,P1143L]-[T19I,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] BA.2.10.4 31 1 3.2% 1 +[W64R,L141-,G142-,V143-,V213G,A243-,L244-,G339D,S494P,A1070V,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] B.1.1.230 30 19 63.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.230 30 4 13.3% 1 +[A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.230 30 2 6.7% 1 +[C1236F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.230 30 2 6.7% 1 +[M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.230 30 1 3.3% 1 +[P631S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.213 30 30 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.506 30 28 93.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.506 30 1 3.3% 1 +[S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.506 30 1 3.3% 1 +[A942T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DW.1 30 22 73.3% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,N460S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DW.1 30 3 10.0% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,N460S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] DW.1 30 2 6.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,N460S,F486V,N703K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DW.1 30 1 3.3% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,N460S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] DW.1 30 1 3.3% 2 +[H69-,V70-,V213G,G339D,V445A,L452R,N460S,F486V,N703K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] B.1.328 30 28 93.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.328 30 1 3.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.328 30 1 3.3% 1 +[L189F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.494 30 20 66.7% 0 +[P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.494 30 9 30.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.494 30 1 3.3% 3 +[+33P,G35-,E96D,P681L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] LA.1 30 17 56.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) LA.1 30 4 13.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] LA.1 30 3 10.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1170P]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] LA.1 30 2 6.7% 1 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] LA.1 30 1 3.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,K529T,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.1.435 30 26 86.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.435 30 1 3.3% 1 +[E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.435 30 1 3.3% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.435 30 1 3.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.435 30 1 3.3% 1 +[D936H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.37 30 27 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.37 30 1 3.3% 1 +[S929I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.37 30 1 3.3% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.37 30 1 3.3% 1 +[G142V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GM.2 30 15 50.0% 0 +[G181R,D253G,P521S]-[G252V] (consensus) GM.2 30 3 10.0% 1 +[F157L,G181R,D253G,P521S]-[G252V] GM.2 30 3 10.0% 1 +[G181R,D253G,S255F,P521S]-[G252V] GM.2 30 2 6.7% 1 +[G181R,D253G,F456L,P521S]-[G252V] GM.2 30 2 6.7% 2 +[H146K,G181R,D253G,S494P,P521S]-[H146Q,G252V] XBB.1.5.84 30 11 36.7% 0 +[M177I] (consensus) XBB.1.5.84 30 4 13.3% 1 +[M177I,E554G] XBB.1.5.84 30 3 10.0% 3 +[M177I,T478I,E554K,S704L]-[T478K] XBB.1.5.84 30 2 6.7% 2 +[M177I,E554G]-[G252V] XBB.1.5.84 30 1 3.3% 1 +[M177I,E554K] B.1.258.6 30 30 100.0% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) GA.3 30 19 63.3% 0 +[D215H] (consensus) GA.3 30 3 10.0% 1 +[D215H,S1123A] GA.3 30 1 3.3% 4 +[D215H,L242-,A243-,L244-,A706V] GA.3 30 1 3.3% 1 +[D215H,E554Q] GA.3 30 1 3.3% 2 +[D215H,E554Q]-[T19I] BL.1.4 30 27 90.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F490V,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BL.1.4 30 1 3.3% 6 +[K147E,W152R,F157L,I210V,V213G,G257S,F490V,D574V]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,D614G,H655Y] BL.1.4 30 1 3.3% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,F490V,D574V,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.1.4 30 1 3.3% 13 +[K147E,W152R,F157L,I210V,V213G,G257S,F490V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,S373P,R408S,N440K,V445P,G446S,N460K,F486P,F490S,D614G] B.1.611 29 26 89.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.611 29 2 6.9% 1 +[T1238A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.611 29 1 3.4% 1 +[C1254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428.1 29 29 100.0% 0 +[A522V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.7 29 21 72.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.7 29 3 10.3% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.7 29 2 6.9% 1 +[G35V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.7 29 2 6.9% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.7 29 1 3.4% 1 +[G261V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.473 29 18 62.1% 0 +[D138Y,N354D,P521R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.473 29 4 13.8% 1 +[D138Y,P521R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.473 29 3 10.3% 3 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.473 29 2 6.9% 1 +[D138Y,N354D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.473 29 1 3.4% 2 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.38.3 29 17 58.6% 0 +[H69F,V70-,S71-,V213G,G339D,K417T,T478R,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,T478K,F486P,F490S] (consensus) BA.2.38.3 29 2 6.9% 8 +[S71F,V213G,G339D,K417T,T478R,Q493R,V1264L]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,T478K,F486P,F490S,N764K] BA.2.38.3 29 1 3.4% 7 +[S71F,V213G,G339D,K417T,T478R,Q493R,V1264L]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,T478K,F486P,F490S] BA.2.38.3 29 1 3.4% 2 +[H69F,V70-,S71-,V213G,G339D,K417T,T478R,Q493R,H1101Y,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,N440K,V445P,G446S,N460K,T478K,F486P,F490S] BA.2.38.3 29 1 3.4% 1 +[H69F,V70-,S71-,V213G,G339D,K417T,T478R,Q493R,E1182Q,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,T478K,F486P,F490S] CM.8.1.3 29 27 93.1% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,Y1272H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] (consensus) CM.8.1.3 29 1 3.4% 2 +[M153T,N164K,V213G,P217T,H245N,G257D,G339D,R408G,K444R,N450D,L452M,E484R,F486S,Y1272H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,E484A,F486P,F490S] CM.8.1.3 29 1 3.4% 1 +[L5F,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,Y1272H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] XCC 29 23 79.3% 0 (consensus) XCC 29 2 6.9% 1 +[L5F] XCC 29 1 3.4% 1 +[G485D] XCC 29 1 3.4% 1 +[S254F] XCC 29 1 3.4% 4 +[F486S]-[Y144-,Q183E,G252V,F486P] V.1 29 27 93.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) V.1 29 1 3.4% 1 +[A222V,P251L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] V.1 29 1 3.4% 1 +[P174S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.12 29 22 75.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.12 29 2 6.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,Y144-,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.12 29 1 3.4% 3 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P,S640F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.12 29 1 3.4% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S640F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.12 29 1 3.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] B.1.508 29 26 89.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.508 29 3 10.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240.2 29 14 48.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240.2 29 13 44.8% 1 +[W64L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.240.2 29 1 3.4% 3 +[W64L,N282S,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240.2 29 1 3.4% 2 +[W64L,L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.84 29 23 79.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.84 29 1 3.4% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.84 29 1 3.4% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.84 29 1 3.4% 2 +[A626S,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.84 29 1 3.4% 2 +[D574Y,R1091H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.515 29 25 86.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.515 29 2 6.9% 2 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.515 29 1 3.4% 3 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.515 29 1 3.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.140 29 24 82.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.140 29 1 3.4% 2 +[S255F,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.140 29 1 3.4% 1 +[D198G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.140 29 1 3.4% 1 +[Y508H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.140 29 1 3.4% 1 +[S13I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HP.1 29 24 82.8% 0 (consensus) HP.1 29 2 6.9% 1 +[E465D] HP.1 29 1 3.4% 1 +[H146K]-[H146Q] HP.1 29 1 3.4% 1 -[K417N] HP.1 29 1 3.4% 1 -[R408S] B.1.321 29 27 93.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.321 29 1 3.4% 1 +[T240I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.321 29 1 3.4% 1 +[M177T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DN.1.1.2 29 21 72.4% 0 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,P479L,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.1.1.2 29 7 24.1% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,P479L,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.1.1.2 29 1 3.4% 2 +[H69-,V70-,K147N,F186S,V213G,G339D,K444T,L452R,P479L,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,F486P,F490S] FL.28 29 22 75.9% 0 +[T478R]-[T478K] (consensus) FL.28 29 2 6.9% 1 +[S71F,T478R]-[T478K] FL.28 29 1 3.4% 8 +[D138Q,P139-,F140-,L141-,G142-,V143-,Y145-,H146-,T478R]-[G142D,H146Q,T478K] FL.28 29 1 3.4% 2 +[T478R]-[V83A,T478K,Y505H] FL.28 29 1 3.4% 1 +[T478R,T732I]-[T478K] B.1.1.360 29 25 86.2% 0 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.360 29 2 6.9% 1 +[R21I,Q183R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.360 29 1 3.4% 2 +[R21I,M731I,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.360 29 1 3.4% 1 +[R21I,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.263 29 16 55.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.263 29 9 31.0% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.263 29 2 6.9% 1 +[F833L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.263 29 1 3.4% 2 +[N450K,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.263 29 1 3.4% 1 +[K147N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XF 29 29 100.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) B.1.287 29 19 65.5% 0 +[E180V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.287 29 6 20.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.287 29 3 10.3% 1 +[E180V,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.287 29 1 3.4% 1 +[E180V,V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.70 29 29 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) JN.1.30.1 29 18 62.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.30.1 29 3 10.3% 1 +[+16MPLF,R21T,S50L,F59L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.30.1 29 3 10.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.30.1 29 1 3.4% 8 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H,N764K] JN.1.30.1 29 1 3.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.615 28 28 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.595.2 28 27 96.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.595.2 28 1 3.6% 1 +[A871S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CM.6.1 28 22 78.6% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,A348S,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.6.1 28 2 7.1% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,A348S,K444R,N450D,L452M,E484R,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.6.1 28 2 7.1% 1 +[M153T,N164K,H207Y,V213G,H245N,G257D,G339D,A348S,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.6.1 28 1 3.6% 3 +[M153T,N164K,V213G,H245N,G257D,G339D,A348S,K444R,N450D,L452M,E484R,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S,N679K,P681H] CM.6.1 28 1 3.6% 1 +[L5F,M153T,N164K,V213G,H245N,G257D,G339D,A348S,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] B.1.1.95 28 26 92.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.95 28 1 3.6% 1 +[A623V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.95 28 1 3.6% 1 +[R765C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.178 28 25 89.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.178 28 1 3.6% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.178 28 1 3.6% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.178 28 1 3.6% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XS 28 24 85.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) XS 28 2 7.1% 1 +[P26S,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XS 28 1 3.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XS 28 1 3.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,S1161P]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AD.2.1 28 26 92.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AD.2.1 28 2 7.1% 1 +[G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.343 28 23 82.1% 0 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.343 28 2 7.1% 1 +[M153T,H655R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.343 28 1 3.6% 1 +[M153T,S691F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.343 28 1 3.6% 1 +[M153T,G184S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.343 28 1 3.6% 1 +[M153T,D1127G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.3 28 26 92.9% 0 +[L18F,T20N,P26S,D138Y,L141-,G142-,V143-,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.3 28 2 7.1% 1 +[L18F,T20N,P26S,I68V,D138Y,L141-,G142-,V143-,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] Q.5 28 28 100.0% 0 +[H69-,V70-,D138H,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) KR.1 28 20 71.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KR.1 28 2 7.1% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KR.1 28 1 3.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] KR.1 28 1 3.6% 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,A520S,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KR.1 28 1 3.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] B.1.428.2 28 20 71.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.428.2 28 3 10.7% 1 +[E780Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428.2 28 3 10.7% 1 +[A263V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428.2 28 1 3.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428.2 28 1 3.6% 2 +[T95I,A263V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.3.3 28 24 85.7% 0 +[F486S,V1122L]-[G252V,F486P] (consensus) XBB.3.3 28 2 7.1% 1 +[F486S,V1122L]-[T19I,G252V,F486P] XBB.3.3 28 2 7.1% 1 +[H146K,F486S,V1122L]-[H146Q,G252V,F486P] B.1.81 28 27 96.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.81 28 1 3.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.4.1 28 19 67.9% 0 +[I870V] (consensus) EG.4.1 28 4 14.3% 1 +[A688V,I870V] EG.4.1 28 2 7.1% 1 +[I870V]-[R408S] EG.4.1 28 1 3.6% 2 +[L5F,I870V]-[R408S] EG.4.1 28 1 3.6% 1 +[D843N,I870V] FL.10.2 28 19 67.9% 0 +[K356T,T523N] (consensus) FL.10.2 28 4 14.3% 1 +[K356T,T523N,G1124V] FL.10.2 28 2 7.1% 1 +[Q14H,K356T,T523N] FL.10.2 28 1 3.6% 1 +[K356T,T523N]-[Y144-] FL.10.2 28 1 3.6% 1 +[P9L,K356T,T523N] GC.1 28 22 78.6% 0 +[T323I] (consensus) GC.1 28 2 7.1% 1 +[T323I,A348S] GC.1 28 1 3.6% 1 +[R214H,T323I] GC.1 28 1 3.6% 3 +[T323I,P1112S]-[V83A,Y505H] GC.1 28 1 3.6% 1 +[T323I,S494P] FL.17.2 28 8 28.6% 0 +[L452R] (consensus) FL.17.2 28 6 21.4% 1 +[L452R,H1101Y] FL.17.2 28 6 21.4% 1 +[L452R,I1130V] FL.17.2 28 3 10.7% 1 +[L452R,L938F] FL.17.2 28 2 7.1% 1 +[G184S,L452R] B.1.187 28 27 96.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.187 28 1 3.6% 1 +[Q14H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.97 28 24 85.7% 0 +[H207R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.97 28 3 10.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.97 28 1 3.6% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.250 28 22 78.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.250 28 2 7.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.250 28 1 3.6% 1 +[S12F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.250 28 1 3.6% 1 +[K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.250 28 1 3.6% 1 +[T323I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XCG 28 11 39.3% 0 +[F486S]-[F486P] (consensus) XCG 28 9 32.1% 1 +[F486S]-[H146Q,F486P] XCG 28 2 7.1% 1 +[F486S]-[K417N,F486P] XCG 28 2 7.1% 1 +[F486S,I844V]-[F486P] XCG 28 1 3.6% 3 +[T478R,F486S,Q607R]-[G142D,T478K,F486P] XBB.1.5.82 27 13 48.1% 0 +[K444R]-[N764K] (consensus) XBB.1.5.82 27 4 14.8% 1 +[K444R] XBB.1.5.82 27 3 11.1% 2 +[K444R,R567K] XBB.1.5.82 27 2 7.4% 2 +[A243-,L244-,K444R]-[N764K] XBB.1.5.82 27 1 3.7% 1 +[K444R]-[Y144-,N764K] B.1.106 27 14 51.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.106 27 7 25.9% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.106 27 5 18.5% 1 +[V289I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.106 27 1 3.7% 2 +[E484Q,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.6 27 20 74.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.6 27 4 14.8% 1 +[S689I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.6 27 1 3.7% 1 +[N1158S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.6 27 1 3.7% 1 +[E1092A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.6 27 1 3.7% 1 +[D1146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GW.4 27 20 74.1% 0 +[E554K] (consensus) GW.4 27 3 11.1% 1 +[E554K,Q607K] GW.4 27 1 3.7% 1 +[G181V,E554K] GW.4 27 1 3.7% 2 +[V62L,G184S,E554K] GW.4 27 1 3.7% 2 +[Y200C,I210T,E554K] JN.1.12 27 12 44.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.12 27 6 22.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.12 27 2 7.4% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S371F,V445P,E484A,F490S,P681H] JN.1.12 27 1 3.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I931V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.12 27 1 3.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] B.1.177.89 27 15 55.6% 0 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.89 27 10 37.0% 1 +[A222V,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.89 27 2 7.4% 2 +[A222V,P272L,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.10 27 22 81.5% 0 +[P9L,L141-,G142-,V143-,I210V,N211-,L212I,S256-,G257-,W258-,V445A,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.10 27 1 3.7% 1 +[P9L,L141-,G142-,V143-,I210V,N211-,L212I,S256-,G257-,W258-,V445A,E484K]-[T19I,L24-,P25-,P26-,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.10 27 1 3.7% 1 +[P9L,L141-,G142-,V143-,N211-,L212I,S256-,G257-,W258-,V445A,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.10 27 1 3.7% 9 +[P9L,I210V,W258S,V445A,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.10 27 1 3.7% 1 +[P9L,L141-,G142-,V143-,W152C,I210V,N211-,L212I,S256-,G257-,W258-,V445A,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.62 27 25 92.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.62 27 1 3.7% 1 +[S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.62 27 1 3.7% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.25 27 18 66.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.25 27 1 3.7% 5 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.25 27 1 3.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.25 27 1 3.7% 16 +[R21T,S50L,V127F,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.25 27 1 3.7% 5 +[S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.479 27 23 85.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.479 27 2 7.4% 1 +[A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.479 27 1 3.7% 1 +[R634L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.479 27 1 3.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XDN 27 20 74.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDN 27 3 11.1% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDN 27 2 7.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDN 27 1 3.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T470I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDN 27 1 3.7% 14 +[S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F490S] B.1.245 27 18 66.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.245 27 4 14.8% 1 +[D253A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.245 27 3 11.1% 1 +[D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.245 27 1 3.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.245 27 1 3.7% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.24 27 13 48.1% 0 +[H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.24 27 6 22.2% 3 +[H69-,V70-,G75V,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.24 27 2 7.4% 1 +[H69-,V70-,L189F,N439K,A688S,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.24 27 2 7.4% 2 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.24 27 2 7.4% 2 +[H69-,V70-,L189F,N439K,S494L,V772I,L1203F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.92 27 26 96.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.92 27 1 3.7% 1 +[A892V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FU.3.1 27 20 74.1% 0 +[E180V,G184S,T478R,S494P,T547I]-[T478K] (consensus) FU.3.1 27 3 11.1% 1 +[E180V,G184S,T478R,T547I]-[T478K] FU.3.1 27 1 3.7% 19 +[L24S,E180V,G184S,T547I]-[L24-,P25-,P26-,A27S,Y144-,G252V,S371F,T376A,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P] FU.3.1 27 1 3.7% 1 +[E180V,G184S,D215G,T478R,S494P,T547I]-[T478K] FU.3.1 27 1 3.7% 1 +[T95I,E180V,G184S,T478R,S494P,T547I]-[T478K] B.1.211 27 26 96.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.211 27 1 3.7% 1 +[A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GK.2.1.1 27 8 29.6% 0 +[L455F,F456L,V511I,P1162S] GK.2.1.1 27 7 25.9% 1 +[H146K,L455F,F456L,V511I,P1162S]-[H146Q] (consensus) GK.2.1.1 27 3 11.1% 3 +[H146K,N211S,L455F,F456L,V511I,P1162S]-[Y144-,H146Q] GK.2.1.1 27 2 7.4% 2 +[H146K,L455F,F456L,V511I,P1162S]-[Y144-,H146Q] GK.2.1.1 27 2 7.4% 2 +[H146K,N211S,L455F,F456L,V511I,P1162S]-[H146Q] B.32 27 27 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.224 27 25 92.6% 0 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.224 27 2 7.4% 1 +[L5F,D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.120 27 25 92.6% 0 +[F565L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.120 27 1 3.7% 1 +[F565L,A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.120 27 1 3.7% 1 +[F565L,D574Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.97 27 27 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.119 27 26 96.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.119 27 1 3.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.254 27 27 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.4.1 27 26 96.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.4.1 27 1 3.7% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BG.7 27 24 88.9% 0 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] (consensus) BG.7 27 2 7.4% 1 +[V213G,G339D,L452Q,Q493R,A647V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BG.7 27 1 3.7% 2 +[V213G,A243-,L244-,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.1.144 26 21 80.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.144 26 2 7.7% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.144 26 2 7.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.144 26 1 3.8% 2 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.47 26 23 88.5% 0 +[L18F,A222V,S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.47 26 1 3.8% 1 +[L18F,A222V,S256L,M731I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.47 26 1 3.8% 1 +[L18F,A222V,S256L,A609V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.47 26 1 3.8% 1 +[L18F,A222V,S256L,I472L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.426 26 15 57.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.426 26 8 30.8% 1 +[A570S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.426 26 2 7.7% 1 +[A623V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.426 26 1 3.8% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.281 26 20 76.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.281 26 2 7.7% 2 +[E156D,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.281 26 2 7.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.281 26 1 3.8% 1 +[E154G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.281 26 1 3.8% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.451 26 26 100.0% 0 +[E156D,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.516 26 22 84.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.516 26 1 3.8% 3 +[V367I,P812L,D1139Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.516 26 1 3.8% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.516 26 1 3.8% 1 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.516 26 1 3.8% 1 +[E554G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.588.1 26 24 92.3% 0 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.588.1 26 2 7.7% 1 +[T20I,D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBN 26 21 80.8% 0 +[F486S]-[G252V,F486P] (consensus) XBN 26 1 3.8% 2 +[F486S,Y1155H]-[G252V,K417N,F486P] XBN 26 1 3.8% 8 +[F486S,P521S]-[L24-,P25-,P26-,A27S,Y144-,H146Q,V213E,G252V,F486P] XBN 26 1 3.8% 1 +[T430I,F486S]-[G252V,F486P] XBN 26 1 3.8% 1 +[N185S,F486S]-[G252V,F486P] XAY.2.3 26 25 96.2% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.2.3 26 1 3.8% 1 +[L18F,T19R,R21G,Q52H,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] B.1.415.1 26 22 84.6% 0 +[H69-,V70-,L242-,R246T,R346K,E484K,N501T,T859N,S982L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.415.1 26 2 7.7% 3 +[R246T,R346K,E484K,N501T,T859N,S982L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.415.1 26 2 7.7% 1 +[H69-,V70-,L242-,R246T,R346K,E484K,N501T,T859N,S982L,E1258D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XAY.2.1 26 22 84.6% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.2.1 26 1 3.8% 7 +[L18F,T19R,R21G,A67V,H69-,V70-,G75V,T95I,V143-,Y145-,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.2.1 26 1 3.8% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.2.1 26 1 3.8% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.2.1 26 1 3.8% 2 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,S255P,G339D,G446E,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XBB.1.3 26 16 61.5% 0 +[E484T,F486S]-[E484A,F486P] (consensus) XBB.1.3 26 2 7.7% 1 +[E484T,F486S]-[T19I,E484A,F486P] XBB.1.3 26 1 3.8% 1 +[E484T,F486S]-[K417N,E484A,F486P] XBB.1.3 26 1 3.8% 2 +[L5F,E484T,F486S]-[K417N,E484A,F486P] XBB.1.3 26 1 3.8% 1 +[L5F,E484T,F486S]-[E484A,F486P] FP.3 26 5 19.2% 0 +[T478R]-[T478K] (consensus) FP.3 26 3 11.5% 1 +[H146K,T478R]-[H146Q,T478K] FP.3 26 3 11.5% 2 +[H146K,R190T,T478R]-[H146Q,T478K] FP.3 26 2 7.7% 1 +[Y248H,T478R]-[T478K] FP.3 26 2 7.7% 2 +[H146K,T478R,T747I]-[H146Q,T478K] C.9 26 14 53.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.9 26 6 23.1% 1 +[D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.9 26 2 7.7% 2 +[T95I,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.9 26 2 7.7% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.9 26 1 3.8% 1 +[W152L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.594 26 23 88.5% 0 +[A344S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.594 26 3 11.5% 1 +[L141F,A344S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.14 26 24 92.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.14 26 2 7.7% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.43 26 19 73.1% 0 +[L8V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.43 26 6 23.1% 1 +[L8V,D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.43 26 1 3.8% 1 +[L8V,A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.60 26 26 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) FK.1.1.1 26 23 88.5% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,V445A,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.1.1 26 1 3.8% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,V445A,L452R,F486S,Q613H]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1.1 26 1 3.8% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,V445A,L452R,I468V,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1.1 26 1 3.8% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,V445A,L452R,F486S,Q613H,G838V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] P.5 26 5 19.2% 0 +[F2L,Q14K,T95I,V143F,E484Q,N501T,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.5 26 4 15.4% 2 +[F2L,Q14K,T95I,V143F,E484Q,N501T,T859I,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.5 26 3 11.5% 1 +[F2L,Q14K,T95I,V143F,E484Q,N501T,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.5 26 3 11.5% 1 +[F2L,Q14K,T95I,V143F,E484Q,N501T,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.5 26 3 11.5% 2 +[F2L,Q14K,T95I,V143F,E484Q,N501T,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] M.1 25 23 92.0% 0 +[T95I,A688S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) M.1 25 1 4.0% 1 +[T95I,A688S,V911I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] M.1 25 1 4.0% 1 +[T95I,A688S,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243.1 25 21 84.0% 0 +[V213G,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.243.1 25 1 4.0% 1 +[V213G,E484K,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243.1 25 1 4.0% 1 +[S12F,V213G,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243.1 25 1 4.0% 1 +[S98F,V213G,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243.1 25 1 4.0% 2 +[V213G,E484K,A522V,V1068I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.437 25 19 76.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.437 25 2 8.0% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.437 25 1 4.0% 2 +[Q677H,V1133F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.437 25 1 4.0% 2 +[A222V,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.437 25 1 4.0% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.504 25 21 84.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.504 25 1 4.0% 1 +[L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.504 25 1 4.0% 1 +[Y1047H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.504 25 1 4.0% 1 +[P57S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.504 25 1 4.0% 1 +[A846S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XV 25 12 48.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XV 25 7 28.0% 1 +[V213G,G339D,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XV 25 4 16.0% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XV 25 2 8.0% 5 +[V213G,G339D,Q493R,V1264L]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DN.3.1 25 10 40.0% 0 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.3.1 25 8 32.0% 1 +[T19L,H69-,V70-,K182E,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.3.1 25 4 16.0% 1 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] DN.3.1 25 1 4.0% 1 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,T478I,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] DN.3.1 25 1 4.0% 1 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,F486P,F490S] B.1.1.382 25 7 28.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.382 25 4 16.0% 2 +[H1083Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.382 25 4 16.0% 2 +[Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.382 25 3 12.0% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.382 25 2 8.0% 2 +[N211S,C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.415 25 23 92.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.415 25 2 8.0% 1 +[T547I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CM.8.1.2 25 14 56.0% 0 +[K147I,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] (consensus) CM.8.1.2 25 3 12.0% 1 +[K147I,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,V483F,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.2 25 3 12.0% 2 +[K147I,M153T,N164K,N211-,L212I,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.2 25 3 12.0% 1 +[K147I,M153T,N164K,V213G,H245N,G257D,G339D,L441F,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.2 25 1 4.0% 1 +[K147I,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,E484A,F486P,F490S] B.1.528 25 9 36.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.528 25 7 28.0% 1 +[V6F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.528 25 2 8.0% 2 +[V6F,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.528 25 1 4.0% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.528 25 1 4.0% 1 +[F4L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.43 25 12 48.0% 0 +[F486S]-[F486P] (consensus) XBB.1.43 25 2 8.0% 1 +[F486S,D796H]-[F486P,D796Y] XBB.1.43 25 2 8.0% 2 +[R190S,R408G,F486S]-[R408S,F486P] XBB.1.43 25 1 4.0% 8 +[V213G,F486S,S940T,S943P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,F486P] XBB.1.43 25 1 4.0% 1 +[R190S,F486S]-[F486P] BQ.1.1.75 25 12 48.0% 0 +[H69-,V70-,K182N,V213G,G339D,K444T,L452R,F456L,F486V,K1086R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.75 25 6 24.0% 1 +[H69-,V70-,K182N,V213G,G339D,K444T,L452R,F456L,F486V,K1086R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.75 25 5 20.0% 1 +[H69-,V70-,K182N,V213G,G339D,K444T,L452R,F456L,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.75 25 1 4.0% 2 +[H69-,V70-,K182N,V213G,G339D,K444T,L452R,F456L,F486V,K1086R,D1139H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.75 25 1 4.0% 1 +[H69-,V70-,K182N,V213G,G339D,K444T,L452R,F456L,F486V,Y660F,K1086R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] GA.4 25 7 28.0% 0 +[D215H,H245Y,K356T,T478R,E554K,S704L]-[T478K] GA.4 25 3 12.0% 4 +[D215H,K356T] GA.4 25 3 12.0% 5 +[D215H,K356T,P621S] GA.4 25 1 4.0% 2 +[D215H,L244F,H245-,K356T,T478R,E554K,S704L]-[T478K] GA.4 25 1 4.0% 7 +[K182I,D215H,Y351H,K356T,S494P] CM.6 25 20 80.0% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.6 25 1 4.0% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,A348S,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.6 25 1 4.0% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,Q1180E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.6 25 1 4.0% 3 +[M153T,N164K,V213G,G339D,K444G,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.6 25 1 4.0% 1 +[M153T,N164K,V213G,H245N,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] EK.1 25 23 92.0% 0 +[K417S]-[K417N] (consensus) EK.1 25 2 8.0% 1 +[K417S]-[G142D,K417N] B.1.1.100 25 25 100.0% 0 +[T385I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AS.1 25 24 96.0% 0 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AS.1 25 1 4.0% 1 +[L54F,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.47 25 24 96.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.47 25 1 4.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.33 25 12 48.0% 0 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BF.33 25 9 36.0% 1 +[H69-,V70-,V213G,G339D,R346I,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BF.33 25 3 12.0% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,F486P,F490S] BF.33 25 1 4.0% 1 +[H69-,V70-,V213G,G339D,R346I,V445F,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.1.29 25 10 40.0% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.29 25 3 12.0% 1 +[H69-,V70-,V213G,G339D,P384A,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.29 25 3 12.0% 1 +[H69-,V70-,V213G,G339Y,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.29 25 2 8.0% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.29 25 1 4.0% 4 +[H69-,V70-,K150E,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N764K,D796Y] B.1.1.137 25 25 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.467 24 22 91.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.467 24 1 4.2% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.467 24 1 4.2% 1 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.99 24 20 83.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.99 24 1 4.2% 2 +[D80Y,S813I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.99 24 1 4.2% 1 +[G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.99 24 1 4.2% 1 +[D178N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.99 24 1 4.2% 1 +[D808E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.381 24 15 62.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.381 24 4 16.7% 1 +[T33I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.381 24 2 8.3% 1 +[G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.381 24 1 4.2% 1 +[A684V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.381 24 1 4.2% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.506 24 24 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.7 24 21 87.5% 0 +[F486S,Q613H]-[G252V,F486P] (consensus) XBB.7 24 1 4.2% 2 +[R214H,D215G,F486S,Q613H]-[G252V,F486P] XBB.7 24 1 4.2% 1 +[F486S,T572I,Q613H]-[G252V,F486P] XBB.7 24 1 4.2% 1 +[G252S,F486S,Q613H]-[G252V,F486P] C.6 24 21 87.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.6 24 1 4.2% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.6 24 1 4.2% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.6 24 1 4.2% 1 +[T573I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XDV.1 24 13 54.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDV.1 24 3 12.5% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDV.1 24 1 4.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1183L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDV.1 24 1 4.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] XDV.1 24 1 4.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K417Y,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] XBC.1.4 24 20 83.3% 0 +[P25S,E156G,F157-,R158-,G184S,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.4 24 2 8.3% 1 +[P25S,E156G,F157-,R158-,G184S,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I,V1228L]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.4 24 1 4.2% 1 +[P25S,E156G,F157-,R158-,G184S,P209L,L212S,D215H,L216F,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.4 24 1 4.2% 1 +[P25S,E156G,F157-,R158-,G184S,P209L,L212S,D215H,A222V,A243-,L244-,S256L,N448D,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] B.1.69 24 22 91.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.69 24 2 8.3% 1 +[L216F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.203 24 22 91.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.203 24 1 4.2% 3 +[L229F,V635I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.203 24 1 4.2% 1 +[A783S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GW.1.1 24 18 75.0% 0 +[F456L,E554K] (consensus) GW.1.1 24 2 8.3% 1 +[F456L,K529N,E554K] GW.1.1 24 1 4.2% 1 +[F456L,E554K,E1188A] GW.1.1 24 1 4.2% 1 +[F456L,E554K]-[T19I] GW.1.1 24 1 4.2% 1 +[G184S,F456L,E554K] XBB.1.5.45 24 11 45.8% 0 +[T478R]-[T478K] (consensus) XBB.1.5.45 24 2 8.3% 3 +[M153I,E180V,G232S,T478R]-[T478K] XBB.1.5.45 24 2 8.3% 1 +[T478R]-[Q183E,T478K] XBB.1.5.45 24 1 4.2% 11 +[T478R]-[L24-,P25-,P26-,A27S,Y144-,Q183E,V213E,G339H,R346T,N460K,T478K,N764K] XBB.1.5.45 24 1 4.2% 2 +[L5F,E96G,T478R]-[T478K] BF.5.3 24 24 100.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.8.1 24 23 95.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,P812R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.8.1 24 1 4.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570V,P812R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.109 24 23 95.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.109 24 1 4.2% 1 +[V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.418 24 23 95.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.418 24 1 4.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.19 23 23 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.394 23 23 100.0% 0 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.82 23 22 95.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.82 23 1 4.3% 3 +[I101T,A222V,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.32 23 21 91.3% 0 +[V6L,E554Q] (consensus) FL.32 23 1 4.3% 1 +[V6L,E554Q,T791A] FL.32 23 1 4.3% 2 +[V6L,H245Y,E554Q,T791A] B.1.1.424 23 18 78.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.424 23 2 8.7% 2 +[T299I,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.424 23 1 4.3% 1 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.424 23 1 4.3% 3 +[A67V,I68-,E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.424 23 1 4.3% 3 +[T678I,A694V,D808N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.56 23 7 30.4% 0 +[G769V,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.56 23 5 21.7% 1 +[H49Y,G769V,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.56 23 5 21.7% 1 +[G769V,A1078S,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.56 23 1 4.3% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.56 23 1 4.3% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.14 23 10 43.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.14 23 7 30.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.14 23 2 8.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.14 23 1 4.3% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S,D796Y] BA.5.1.14 23 1 4.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,K854N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.4.5 23 19 82.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.4.5 23 2 8.7% 1 +[G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.5 23 2 8.7% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.9.6 23 19 82.6% 0 +[R403K,F486S,A570T]-[F486P] (consensus) XBB.1.9.6 23 2 8.7% 1 +[R403K,F486S,A570T]-[F486P,Q498R] XBB.1.9.6 23 1 4.3% 1 +[R403K,F486S,A570T]-[R408S,F486P] XBB.1.9.6 23 1 4.3% 1 +[R403K,F486S,A570T,L981I]-[F486P] XAY.1.1.3 23 7 30.4% 0 +[L18F,T19R,R21G,T95I,N148D,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] XAY.1.1.3 23 4 17.4% 2 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F490S] XAY.1.1.3 23 4 17.4% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.1.1.3 23 1 4.3% 2 +[L5F,L18F,T19R,R21G,T95I,N148D,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,A942S,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] XAY.1.1.3 23 1 4.3% 4 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,S477N,F490S,Q954H] B.1.492 23 23 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) DV.7.2 23 22 95.7% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.7.2 23 1 4.3% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,L858I,L1197F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BN.3 23 4 17.4% 0 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BN.3 23 4 17.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BN.3 23 3 13.0% 5 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BN.3 23 2 8.7% 2 +[P9L,K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BN.3 23 1 4.3% 8 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H] B.1.304 23 21 91.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.304 23 1 4.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.304 23 1 4.3% 1 +[D574Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1 23 16 69.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1 23 1 4.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1 23 1 4.3% 9 +[V213G,G257S,G339D,K444T,F486S]-[Q183E,V213E,G252V,G339H,R346T,L368I,V445P,F486P,F490S] CH.1 23 1 4.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,F486S,E1151Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1 23 1 4.3% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,F486S,A688V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] HK.5 23 13 56.5% 0 +[Q52H,F456L,Q677H] (consensus) HK.5 23 3 13.0% 1 +[Q52H,F456L,Q677H,N710S] HK.5 23 1 4.3% 1 +[Q52H,D427V,F456L,Q677H] HK.5 23 1 4.3% 1 +[Q14R,Q52H,F456L,Q677H] HK.5 23 1 4.3% 1 +[Q52H,F456L,Q677H,I1221V] XAY.3 23 13 56.5% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.3 23 8 34.8% 1 +[L5F,L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.3 23 1 4.3% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.3 23 1 4.3% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,T678I,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] GK.2.2 23 17 73.9% 0 +[L455F,F456L,V511I,E554D] (consensus) GK.2.2 23 3 13.0% 1 +[L455F,F456L,V511I,E554D,T732I] GK.2.2 23 1 4.3% 1 +[V308I,L455F,F456L,V511I,E554D] GK.2.2 23 1 4.3% 3 +[L455F,F456L,V511I,E554D,T732I]-[Y144-,F490S] GK.2.2 23 1 4.3% 2 +[L455F,F456L,V511I,E554D]-[V83A,Y505H] HL.1 23 21 91.3% 0 +[E583D,Q613H] (consensus) HL.1 23 1 4.3% 4 +[E583D,Q613H]-[G142D,R408S,V445P,G446S] HL.1 23 1 4.3% 4 +[Y248W,+248GAN,E583D,Q613H] B.5 23 22 95.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.5 23 1 4.3% 1 +[P1079T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.115 23 15 65.2% 0 +[A706S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.115 23 6 26.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.115 23 1 4.3% 1 +[V83I,A706S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.115 23 1 4.3% 2 +[A783S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.107 23 21 91.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.107 23 2 8.7% 2 +[K854M,S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.122 23 20 87.0% 0 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.122 23 1 4.3% 1 +[L5F,T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.122 23 1 4.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.122 23 1 4.3% 1 +[T20I,S884F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.15 23 21 91.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.15 23 1 4.3% 1 +[A831V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.15 23 1 4.3% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.248 23 22 95.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.248 23 1 4.3% 1 +[I105V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.67 23 15 65.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.67 23 4 17.4% 1 +[H146R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.67 23 3 13.0% 2 +[H146R,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.67 23 1 4.3% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.40 23 14 60.9% 0 +[L5F,H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.40 23 4 17.4% 1 +[L5F,H49Y,H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.40 23 3 13.0% 1 +[L5F,H69-,V70-,V213G,G339D,N450D,L452R,Y453F,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.40 23 2 8.7% 1 +[L5F,H69-,V70-,V213G,Q321K,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.396 22 14 63.6% 0 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.396 22 1 4.5% 2 +[E96D,S112L,M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.396 22 1 4.5% 3 +[E96D,S112L,M153T,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.396 22 1 4.5% 2 +[T20I,M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] B.1.1.396 22 1 4.5% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] AK.2 22 22 100.0% 0 +[I834T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.24 22 5 22.7% 0 +[S255F] (consensus) XBB.1.24 22 4 18.2% 1 XBB.1.24 22 4 18.2% 2 +[S255F,P521T,L828F] XBB.1.24 22 2 9.1% 2 +[F157L] XBB.1.24 22 2 9.1% 2 -[K417N] B.1.276 22 21 95.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.276 22 1 4.5% 1 +[G446D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.512 22 6 27.3% 0 +[Q677H,A1078S,I1232F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.512 22 6 27.3% 1 +[D80Y,Q677H,A1078S,I1232F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.512 22 4 18.2% 1 +[A1078S,I1232F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.512 22 3 13.6% 2 +[A67V,D80Y,Q677H,A1078S,I1232F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.512 22 2 9.1% 2 +[L18F,A1078S,I1232F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.635 22 12 54.5% 0 +[H49Y,L141-,G142-,V143-,T259R,N450K]-[L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.635 22 2 9.1% 1 +[H49Y,L141-,G142-,V143-,T259R,N450K,S494P]-[L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.635 22 1 4.5% 5 +[H49Y,N450K]-[L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.635 22 1 4.5% 1 +[H49Y,L141-,G142-,V143-,T259R,N450K]-[L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.635 22 1 4.5% 1 +[H49Y,L141-,G142-,V143-,T259R,N450K,T678I]-[L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBW 22 21 95.5% 0 (consensus) XBW 22 1 4.5% 1 +[S12P] B.1.1.359 22 9 40.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.359 22 3 13.6% 1 +[E484Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.359 22 2 9.1% 1 +[N1023K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.359 22 2 9.1% 1 +[T1077S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.359 22 1 4.5% 1 +[T630S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.8 22 12 54.5% 0 +[+186SGG,F486S]-[F486P] (consensus) XBB.1.8 22 4 18.2% 1 +[+186SGG,F486S,F565L]-[F486P] XBB.1.8 22 2 9.1% 1 +[+186SGG,F486S,R646H]-[F486P] XBB.1.8 22 2 9.1% 3 +[F486S]-[F486P] XBB.1.8 22 1 4.5% 1 +[+186SGG,F486S]-[Y144-,F486P] A.7 22 19 86.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.7 22 1 4.5% 1 +[T761S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.7 22 1 4.5% 1 +[A930T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.7 22 1 4.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.510 22 21 95.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.510 22 1 4.5% 1 +[N1074D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.566 22 12 54.5% 0 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.566 22 7 31.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.566 22 2 9.1% 3 +[L5F,T29I,A67S,S221L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.566 22 1 4.5% 2 +[M731I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10.2 22 12 54.5% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.10.2 22 10 45.5% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] XBJ.3 22 19 86.4% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) XBJ.3 22 1 4.5% 2 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,D1139N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S,P681H] XBJ.3 22 1 4.5% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,E484A,F486P,F490S] XBJ.3 22 1 4.5% 5 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,V503-,G504-]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S,Q498R,N501Y,Y505H] XBB.1.29 22 10 45.5% 0 +[A292S,F486S]-[F486P] (consensus) XBB.1.29 22 4 18.2% 1 +[A292S,F486S]-[K417N,F486P] XBB.1.29 22 3 13.6% 3 +[A292S,E484V,F486S,A684T,A1078S]-[E484A,F486P] XBB.1.29 22 2 9.1% 1 +[A292S,F486S,A1078S]-[F486P] XBB.1.29 22 1 4.5% 2 +[A292S,F486S,A1078S]-[K417N,F486P] XBB.1.28 22 6 27.3% 0 +[R403K,L461I,F486S,N556S]-[F486P] XBB.1.28 22 2 9.1% 6 +[L335S,R403K,T478R,I1227V]-[T478K] XBB.1.28 22 1 4.5% 2 +[R403K,F486S,N556K]-[F486P] XBB.1.28 22 1 4.5% 4 +[+344A,R346-,R403K,F486S]-[R346T,F486P] XBB.1.28 22 1 4.5% 4 +[A344V,R403K,F486S,G1124S]-[F486P] B.1.264.1 22 11 50.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.264.1 22 4 18.2% 1 +[Q677R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.264.1 22 1 4.5% 1 +[C1248F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.264.1 22 1 4.5% 1 +[T678I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.264.1 22 1 4.5% 3 +[Q675R,Q677R,T719I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.442 22 18 81.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.442 22 1 4.5% 1 +[T618I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.442 22 1 4.5% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.442 22 1 4.5% 1 +[A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.442 22 1 4.5% 1 +[M740I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.418 22 20 90.9% 0 +[T732A,A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.418 22 1 4.5% 1 +[L5F,T732A,A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.418 22 1 4.5% 1 +[T732A,A879S,G1219A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.3 22 16 72.7% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AA.3 22 4 18.2% 1 +[A222V,D627H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.3 22 1 4.5% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AA.3 22 1 4.5% 1 +[A222V,P1112S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.392 22 19 86.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.392 22 1 4.5% 1 +[Y789H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.392 22 1 4.5% 1 +[Y28F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.392 22 1 4.5% 1 +[I569T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.87 22 11 50.0% 0 +[T478R]-[T478K] (consensus) XBB.1.5.87 22 3 13.6% 1 +[T478R]-[K417N,T478K] XBB.1.5.87 22 1 4.5% 3 +[P251S,T478R]-[G142D,K417N,T478K] XBB.1.5.87 22 1 4.5% 1 +[A475V,T478R]-[T478K] XBB.1.5.87 22 1 4.5% 1 -[T478K] B.1.1.116 22 21 95.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.116 22 1 4.5% 2 +[M153I,D808N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.496 22 21 95.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.496 22 1 4.5% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.545 22 19 86.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.545 22 1 4.5% 2 +[T73I,F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.545 22 1 4.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.545 22 1 4.5% 1 +[S691P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.12 21 14 66.7% 0 +[D253G,F486S,Q613H]-[G252V,F486P] (consensus) XBB.2.12 21 2 9.5% 6 +[D253G,F486S,T572I,Q613H]-[L24-,P25-,P26-,A27S,Y144-,G252V,F486P] XBB.2.12 21 1 4.8% 2 +[L54F,K77N,D253G,F486S,Q613H]-[G252V,F486P] XBB.2.12 21 1 4.8% 6 +[L5F,Y145P,H146-,F186L,D253G,F486S,Q613H,A890V]-[Y144-,H146Q,G252V,F486P] XBB.2.12 21 1 4.8% 4 +[Y145P,H146-,D253G,F486S,Q613H]-[V83A,Y144-,H146Q,G252V,F486P] B.1.1.152 21 16 76.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.152 21 1 4.8% 1 +[S155G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.152 21 1 4.8% 3 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.152 21 1 4.8% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.152 21 1 4.8% 2 +[G181A,G1251R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EA.2 21 19 90.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,T470I,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EA.2 21 1 4.8% 1 +[H69-,V70-,N185D,V213G,G339D,K444T,L452R,T470I,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EA.2 21 1 4.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,T470I,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] JN.8 21 18 85.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.8 21 2 9.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] JN.8 21 1 4.8% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T299I,I332V,K356T,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] AF.1 21 19 90.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AF.1 21 2 9.5% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.514 21 17 81.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.514 21 3 14.3% 1 +[T73I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.514 21 1 4.8% 2 +[T73I,S691F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.345 21 18 85.7% 0 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.345 21 2 9.5% 2 +[E484K,A701V,L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.345 21 1 4.8% 1 +[E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.309 21 10 47.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.309 21 5 23.8% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.309 21 3 14.3% 1 +[P384S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.309 21 1 4.8% 1 +[G142V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.309 21 1 4.8% 1 +[V615F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.480 21 15 71.4% 0 +[W258L,E1258V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.480 21 6 28.6% 1 +[E1258V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.458 21 9 42.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.458 21 5 23.8% 1 +[A163V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.458 21 4 19.0% 1 +[V213L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.458 21 1 4.8% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.458 21 1 4.8% 2 +[V213L,I1169F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.9 21 19 90.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.9 21 1 4.8% 2 +[L5F,S1037P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.9 21 1 4.8% 1 +[E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.77 21 19 90.5% 0 +[H69-,V70-,V213G,G339D,E340K,K356T,L452R,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.77 21 1 4.8% 1 +[H69-,V70-,V213G,G339D,E340K,K356T,L452R,L752F,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.77 21 1 4.8% 1 +[H69-,V70-,V213G,G339D,E340K,K356T,L452R,D936H,K1073T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] KP.4.2 21 12 57.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KP.4.2 21 5 23.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,G257R,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.4.2 21 2 9.5% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.4.2 21 1 4.8% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.4.2 21 1 4.8% 8 +[R21T,F32L,S50L,F59I,H69-,V70-,V127F,F157S,R158G,K187R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,V1104L,P1143L,E1144Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] KU.2 21 15 71.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KU.2 21 2 9.5% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KU.2 21 1 4.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KU.2 21 1 4.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,N764K] KU.2 21 1 4.8% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A522S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] EP.2 21 12 57.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F486S,T572I,S1147L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) EP.2 21 2 9.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F486S,T572I,S1147L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.2 21 2 9.5% 2 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,F486S,T572I,S1147L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.2 21 2 9.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F486S,T572I,D1084H,S1147L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.2 21 1 4.8% 2 +[K147E,W152R,F157L,I210V,V213G,+253F,G257-,K356T,F486S,T572I,S1147L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AM.3 21 21 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.9.3 21 19 90.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.9.3 21 2 9.5% 1 +[A260V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.208 21 17 81.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.208 21 2 9.5% 1 +[T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.208 21 1 4.8% 1 +[T791I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.208 21 1 4.8% 2 +[T572I,N1192S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.98 21 12 57.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.98 21 8 38.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.98 21 1 4.8% 2 +[K1073R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.379 21 16 76.2% 0 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.379 21 2 9.5% 1 +[R21I,T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.379 21 2 9.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.379 21 1 4.8% 1 +[R21I,F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAY.1.1.2 21 17 81.0% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.1.1.2 21 2 9.5% 1 +[L18F,T19R,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] XAY.1.1.2 21 1 4.8% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] XAY.1.1.2 21 1 4.8% 4 +[L18F,T19R,R21G,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,S477N,F490S,Y505H] AY.19 21 10 47.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.19 21 8 38.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.19 21 2 9.5% 1 +[T19R,E156G,F157-,R158-,A372V,L452R,P681R,D950N,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.19 21 1 4.8% 4 +[T19R,L452R,P681R,D950N,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.38.1 21 11 52.4% 0 +[F486S,T732I,T883I]-[F486P] (consensus) XBB.1.38.1 21 1 4.8% 1 +[F486S,I666V,T732I,T883I]-[F486P] XBB.1.38.1 21 1 4.8% 2 +[F486S,T732I,T883I]-[Y144-,K417N,F486P] XBB.1.38.1 21 1 4.8% 1 +[F486S,T732I,T883I,M1237I]-[F486P] XBB.1.38.1 21 1 4.8% 1 +[H146K,F486S,T732I,T883I]-[H146Q,F486P] FL.10.3 21 19 90.5% 0 +[G181R] (consensus) FL.10.3 21 1 4.8% 1 +[G181R]-[Y144-] FL.10.3 21 1 4.8% 1 +[G181R,F486S]-[F486P] BM.3 21 12 57.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BM.3 21 2 9.5% 1 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BM.3 21 1 4.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,F486P,F490S] BM.3 21 1 4.8% 2 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,R408S,V445P,F486P,F490S] BM.3 21 1 4.8% 2 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,P272H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] B.1.1.145 21 20 95.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.145 21 1 4.8% 1 +[G261V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.13.1 21 18 85.7% 0 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V,P681Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,P681H] (consensus) BF.7.13.1 21 1 4.8% 2 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V,P681Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S,P681H] BF.7.13.1 21 1 4.8% 1 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V,P681Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BF.7.13.1 21 1 4.8% 1 +[H69-,V70-,V213G,G339D,T430I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.18 21 17 81.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.18 21 3 14.3% 1 +[K97N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.18 21 1 4.8% 17 +[I68-,H69-,V70-,S71-,G72-,T73-,N74-,G75-,T76-,R102G,T676-,Q677-,T678-,N679-,S680-,S813I,T1136A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.2 21 10 47.6% 0 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.25.2 21 3 14.3% 1 +[L5F,T19R,E156G,F157-,R158-,N188S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.2 21 2 9.5% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.2 21 2 9.5% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N,S1252P]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.2 21 2 9.5% 1 +[L5F,T19R,A27V,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.2 21 14 66.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.2 21 6 28.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,G181R,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.2 21 1 4.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,T638R,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] CP.1.3 21 20 95.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,N460K,F486P,F490S] (consensus) CP.1.3 21 1 4.8% 1 +[H69-,V70-,S155N,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,N460K,F486P,F490S] B.51 20 18 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.51 20 1 5.0% 1 +[V687I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.51 20 1 5.0% 1 +[I598V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.4 20 19 95.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.4 20 1 5.0% 1 +[L513F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.1 20 15 75.0% 0 +[T19R,T29A,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.103.1 20 2 10.0% 1 +[T19R,T29A,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.1 20 1 5.0% 1 +[L5F,T19R,T29A,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.1 20 1 5.0% 1 +[T19R,T29A,E156G,F157-,R158-,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.1 20 1 5.0% 1 +[T19R,T29A,E156G,F157-,R158-,L452R,P681R,Q779K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.231 20 20 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.40 20 14 70.0% 0 +[D215H,L244-,H245-,R246-,S247-,L452R,S640F,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.40 20 3 15.0% 2 +[T22I,D215H,L244-,H245-,R246-,S247-,L452R,S640F,S810L,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.40 20 2 10.0% 3 +[T22I,D215H,L244-,H245-,R246-,S247-,L452R,K558N,S640F,T859N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.40 20 1 5.0% 1 +[D215H,L244-,H245-,R246-,S247-,L452R,S640F,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.430 20 18 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.430 20 1 5.0% 1 +[A694V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.430 20 1 5.0% 1 +[A348S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.2.4 20 15 75.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L242F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.2.4 20 1 5.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L242F,H245N,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.4 20 1 5.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L242F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] JN.2.4 20 1 5.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L242F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,F515L,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.2.4 20 1 5.0% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L242F,H245N,I332V,K356T,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.358 20 18 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.358 20 1 5.0% 1 +[V1177L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.358 20 1 5.0% 1 +[V615I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CM.11 20 19 95.0% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.11 20 1 5.0% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,E484A,F486P,F490S] B.1.601 20 20 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6.4 20 20 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) CM.7.1.1 20 7 35.0% 0 +[K147E,M153T,N164K,V213G,H245N,G257D,G339D,R403K,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.7.1.1 20 6 30.0% 1 +[K147E,M153T,N164K,V213G,H245N,S255A,G257D,G339D,R403K,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.7.1.1 20 2 10.0% 1 +[K147E,M153T,N164K,V213G,H245N,G257D,G339D,R403K,K444R,N450D,L452M,E484R,F486S,V622I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.7.1.1 20 1 5.0% 1 +[K147E,M153T,N164K,V213G,H245N,G257D,G339D,R403K,K444R,N450D,L452M,A475S,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.7.1.1 20 1 5.0% 1 +[K147E,M153T,N164K,V213G,H245N,G257D,G339D,R403K,K444R,N450D,L452M,E484R,F486S,A684T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] HU.2 20 13 65.0% 0 +[T76I] (consensus) HU.2 20 5 25.0% 2 +[I68T,T76I,S256L] HU.2 20 1 5.0% 1 +[T76I,G1124V] HU.2 20 1 5.0% 1 +[L5F,T76I] HU.1 20 17 85.0% 0 +[K529N] (consensus) HU.1 20 1 5.0% 1 +[E471Q,K529N] HU.1 20 1 5.0% 1 +[L5F,K529N] HU.1 20 1 5.0% 1 +[D253Y,K529N] XBB.1.25 20 7 35.0% 0 +[F486S]-[F486P] (consensus) XBB.1.25 20 3 15.0% 1 +[F486S]-[Q183E,F486P] XBB.1.25 20 2 10.0% 1 +[F486S]-[K417N,F486P] XBB.1.25 20 1 5.0% 1 +[T307I,F486S]-[F486P] XBB.1.25 20 1 5.0% 1 +[T323I,F486S]-[F486P] B.1.1.271 20 8 40.0% 0 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.271 20 7 35.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.271 20 2 10.0% 4 +[H66R,E96G,S247R,Q677H,R1091C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.271 20 1 5.0% 4 +[E180G,H245R,E484D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.271 20 1 5.0% 6 +[+213QK,+214LR,E484D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XAW 20 11 55.0% 0 +[L5F,T19R,P25L,V143D,Y145-,E156G,F157-,R158-,N211-,L212I,D215Y,A243-,L244-,G339D,G446D,S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N679K] (consensus) XAW 20 7 35.0% 1 +[L5F,T19R,P25L,V143D,Y145-,E156G,F157-,R158-,N211-,L212I,A243-,L244-,G339D,G446D,S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N679K] XAW 20 2 10.0% 1 +[L5F,T19R,P25L,V143D,Y145-,E156G,F157-,R158-,N211-,L212I,D215Y,A243-,L244-,G339D,G446D,S494P,V642F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N679K] XBB.1.26 20 18 90.0% 0 +[F486S]-[F486P] (consensus) XBB.1.26 20 1 5.0% 1 +[F486S,L517F]-[F486P] XBB.1.26 20 1 5.0% 1 +[F486S,T1160I]-[F486P] B.1.1.447 20 11 55.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.447 20 8 40.0% 1 +[V1068F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.447 20 1 5.0% 1 +[E918G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.77 20 19 95.0% 0 +[S247G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.77 20 1 5.0% 1 +[W152R,S247G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.86.5 20 10 50.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) BA.2.86.5 20 4 20.0% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.5 20 3 15.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.5 20 1 5.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] BA.2.86.5 20 1 5.0% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,F486S,E554K,A570V,T572I,P621S,A672V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] XC 20 13 65.0% 0 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XC 20 3 15.0% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N,Q1201R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XC 20 3 15.0% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,L585F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XC 20 1 5.0% 2 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N,Q1201R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AC.1 19 19 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.242 19 13 68.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.242 19 3 15.8% 1 +[Y28H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.242 19 3 15.8% 1 +[L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.538 19 16 84.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.538 19 2 10.5% 1 +[A243S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.538 19 1 5.3% 1 +[S884F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.31 19 11 57.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.31 19 3 15.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.31 19 2 10.5% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.31 19 1 5.3% 2 +[P272L,C1247F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.31 19 1 5.3% 1 +[P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.19 19 5 26.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.19 19 3 15.8% 1 +[T719N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.19 19 2 10.5% 2 +[T315N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.19 19 1 5.3% 2 +[E654V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] A.19 19 1 5.3% 1 +[S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.13 19 19 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.49 19 14 73.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.49 19 2 10.5% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.49 19 1 5.3% 1 +[A871S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.49 19 1 5.3% 1 +[M1233V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.49 19 1 5.3% 1 +[E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FA.2 19 17 89.5% 0 +[H69-,V70-,V213G,T323I,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) FA.2 19 1 5.3% 1 +[H69-,V70-,V213G,T323I,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FA.2 19 1 5.3% 1 +[L18I,H69-,V70-,V213G,T323I,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] C.33 19 9 47.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.33 19 5 26.3% 2 +[L18F,S221L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.33 19 3 15.8% 1 +[R78M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.33 19 1 5.3% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.33 19 1 5.3% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.4 19 18 94.7% 0 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) L.4 19 1 5.3% 1 +[N556K,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.8 19 15 78.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.8 19 2 10.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.8 19 1 5.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.8 19 1 5.3% 1 +[V1133F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.592 19 10 52.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.592 19 9 47.4% 1 +[N1074D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CA.6 19 12 63.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CA.6 19 3 15.8% 1 +[G72E,K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.6 19 1 5.3% 8 +[K147E,F157L,V213G,F486S,D1199N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.6 19 1 5.3% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P,F490S] CA.6 19 1 5.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] EG.10 19 5 26.3% 0 +[A344T,R403K] EG.10 19 3 15.8% 2 +[A344T,R403K,S494P,A701V] EG.10 19 2 10.5% 3 +[H146K,A344T,R403K,S494P,A701V]-[H146Q] EG.10 19 1 5.3% 1 +[A344T] EG.10 19 1 5.3% 3 +[A344T,R403K,S494P,A701V,D1184Y] GN.2 19 15 78.9% 0 (consensus) GN.2 19 2 10.5% 1 +[S31F] GN.2 19 2 10.5% 1 +[R577L] FL.30 19 10 52.6% 0 +[E484K,A852S]-[E484A] (consensus) FL.30 19 3 15.8% 1 +[E484K,A852S]-[K417N,E484A] FL.30 19 2 10.5% 2 +[D253N,E484K,V785I,A852S]-[E484A] FL.30 19 2 10.5% 1 +[H146K,E484K,A852S]-[H146Q,E484A] FL.30 19 1 5.3% 1 +[E484K,G485D,A852S]-[E484A] XBB.1.5.29 19 16 84.2% 0 +[A348V] (consensus) XBB.1.5.29 19 2 10.5% 1 +[A348V,C1247F] XBB.1.5.29 19 1 5.3% 1 +[A348V,G932S] JN.1.48 19 7 36.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.48 19 3 15.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1085E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.48 19 3 15.8% 7 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.48 19 1 5.3% 2 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.48 19 1 5.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] G.1 19 19 100.0% 0 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.417 19 8 42.1% 0 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.417 19 6 31.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.417 19 3 15.8% 1 +[F175S,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.417 19 1 5.3% 1 +[L5F,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.417 19 1 5.3% 2 +[F175S,S939F,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.513 19 19 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.446 19 14 73.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.446 19 1 5.3% 2 +[H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.446 19 1 5.3% 2 +[K150Q,L179F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.446 19 1 5.3% 1 +[V826M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.446 19 1 5.3% 2 +[V367F,I1115V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.361 19 19 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.86 19 16 84.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.86 19 1 5.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.86 19 1 5.3% 1 +[F157S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.86 19 1 5.3% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.180 19 18 94.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.180 19 1 5.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.340 19 15 78.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.340 19 1 5.3% 2 +[S13I,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.340 19 1 5.3% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.340 19 1 5.3% 2 +[Q677H,L1200F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.340 19 1 5.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.227 19 7 36.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.227 19 4 21.1% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.227 19 3 15.8% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.227 19 3 15.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.227 19 1 5.3% 2 +[W258L,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.19 19 18 94.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.19 19 1 5.3% 1 +[D745G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.489 19 19 100.0% 0 +[D936Y,A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.310 19 19 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XCF.2 19 15 78.9% 0 +[F456L,S929I] (consensus) XCF.2 19 2 10.5% 1 +[F456L,S704L,S929I] XCF.2 19 1 5.3% 2 +[F456L,P681Y,S929I,P1162S]-[P681H] XCF.2 19 1 5.3% 1 +[E180K,F456L,S929I] XBJ.1 18 9 50.0% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) XBJ.1 18 8 44.4% 2 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,N481S,G482-,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBJ.1 18 1 5.6% 1 +[Y28H,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] C.36.2 18 8 44.4% 0 +[Q677H,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.36.2 18 5 27.8% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.2 18 2 11.1% 2 +[Q677H,P793L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.2 18 1 5.6% 2 +[Q677H,A1078V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.2 18 1 5.6% 1 +[Q677H,A845S,A1078V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.39 18 10 55.6% 0 +[P9L,Y144C,Y145-,R190K,L452Q,P479S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.39 18 6 33.3% 1 +[P9L,Y144C,Y145-,R190K,P330S,L452Q,P479S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.39 18 1 5.6% 1 +[P9L,Y144C,Y145-,L452Q,P479S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.39 18 1 5.6% 2 +[P9L,R190K,L452Q,P479S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.39.1 18 17 94.4% 0 +[H69-,V70-,G181V,V213G,G339D,V445A,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.39.1 18 1 5.6% 1 +[H69-,V70-,K147I,G181V,V213G,G339D,V445A,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.324 18 13 72.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.324 18 2 11.1% 1 +[S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.324 18 2 11.1% 1 +[D1260N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.324 18 1 5.6% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.438 18 14 77.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.438 18 2 11.1% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.438 18 1 5.6% 1 +[V576I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.438 18 1 5.6% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.49 18 17 94.4% 0 +[L54F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.49 18 1 5.6% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CV.2 18 10 55.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] (consensus) CV.2 18 2 11.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] CV.2 18 1 5.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,A879T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] CV.2 18 1 5.6% 1 +[I68T,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] CV.2 18 1 5.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G482S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] XAY.2.2 18 11 61.1% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.2.2 18 2 11.1% 1 +[L5F,L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.2.2 18 1 5.6% 1 +[L18F,T19R,R21G,I68V,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.2.2 18 1 5.6% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I,D1165N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.2.2 18 1 5.6% 2 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,A397V,G446D,L452R,P621S,A706V,T791I,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] XAY.1.1 18 11 61.1% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.1.1 18 1 5.6% 3 +[L18F,T19R,R21G,H69-,V70-,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] XAY.1.1 18 1 5.6% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,R214H,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] XAY.1.1 18 1 5.6% 3 +[L18F,T19R,R21G,T95I,W152L,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] XAY.1.1 18 1 5.6% 1 +[L18F,T19R,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F490S] JN.1.8.2 18 13 72.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.8.2 18 1 5.6% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.8.2 18 1 5.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,A668S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.8.2 18 1 5.6% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,L179F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.8.2 18 1 5.6% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V687L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.1.72 18 11 61.1% 0 +[T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.72 18 4 22.2% 1 +[H49Y,T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.72 18 2 11.1% 2 +[V62L,T747I,L806Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.72 18 1 5.6% 1 +[K529N,T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BM.5 18 10 55.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BM.5 18 3 16.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,F486P,F490S] BM.5 18 1 5.6% 5 +[K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,F486P,F490S] BM.5 18 1 5.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S,H655Y] BM.5 18 1 5.6% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,L455S,S884F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S,H655Y] LA.2 18 18 100.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XBB.1.19 18 5 27.8% 0 (consensus) XBB.1.19 18 3 16.7% 2 +[S151I,K182R] XBB.1.19 18 1 5.6% 1 +[V1228L] XBB.1.19 18 1 5.6% 1 +[A260T] XBB.1.19 18 1 5.6% 1 +[K182R] CM.8.1.5 18 9 50.0% 0 +[K150E,M153T,N164K,V213G,H245N,Y248H,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] (consensus) CM.8.1.5 18 2 11.1% 1 +[K150E,M153T,N164K,V213G,H245N,Y248H,G257D,G339D,K444R,N450D,L452M,T478R,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,T478K,E484A,F486P,F490S] CM.8.1.5 18 2 11.1% 2 +[K150E,M153T,N164K,V213G,H245N,Y248H,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.5 18 1 5.6% 1 +[K150E,M153T,N164K,V213G,H245N,Y248H,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1.5 18 1 5.6% 1 +[K150E,M153T,N164K,V213G,H245N,Y248H,G257D,G339D,K444R,N450D,L452M,E484R,F486S,T553I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] B.1.1.77 18 12 66.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.77 18 3 16.7% 1 +[S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.77 18 2 11.1% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.77 18 1 5.6% 2 +[S98F,S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.1.4.3 18 17 94.4% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.4.3 18 1 5.6% 1 +[H69-,V70-,V213G,Y248H,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.529 18 13 72.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.529 18 2 11.1% 1 +[A27E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.529 18 1 5.6% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.529 18 1 5.6% 1 +[P9L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.529 18 1 5.6% 1 +[V36I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.383 18 14 77.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.383 18 2 11.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.383 18 2 11.1% 1 +[K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.407 18 18 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XCD 18 8 44.4% 0 +[R214H,T478I]-[T478K] (consensus) XCD 18 6 33.3% 1 +[G72V,R214H,T478I]-[T478K] XCD 18 2 11.1% 1 +[R214H,T478I]-[K417N,T478K] XCD 18 1 5.6% 3 +[K150N,R214H,T478I]-[G142D,K417N,T478K] XCD 18 1 5.6% 2 +[R214H,T478I,A694V,V963I]-[T478K] HB.1 17 5 29.4% 0 +[H146K,K182I,F456L,P681R]-[H146Q,P681H] HB.1 17 4 23.5% 3 +[K182I,F456L,T478R,P681R]-[Y144-,T478K,P681H] HB.1 17 2 11.8% 2 +[H146K,K182I,F456L,T478R,E554K,P681R]-[H146Q,T478K,P681H] HB.1 17 1 5.9% 4 +[K182I,L455F,F456L,T478R,P681R]-[Y144-,T478K,P681H] HB.1 17 1 5.9% 1 +[H146K,K182I,F456L,T478R,P681R]-[H146Q,T478K,P681H] (consensus) B.1.177.37 17 17 100.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.318 17 12 70.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.318 17 3 17.6% 2 +[A163V,T1120I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.318 17 2 11.8% 1 +[A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.537 17 12 70.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.537 17 1 5.9% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.537 17 1 5.9% 2 +[M153I,D1199Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.537 17 1 5.9% 1 +[G75R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.537 17 1 5.9% 4 +[H146Y,Q675H,K1073T,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.7.4 17 13 76.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.7.4 17 1 5.9% 6 +[R21-,+22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.7.4 17 1 5.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.7.4 17 1 5.9% 1 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.7.4 17 1 5.9% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,Y144N,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.441 17 7 41.2% 0 +[V6F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.441 17 5 29.4% 3 +[G769V,E1207D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.441 17 4 23.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.441 17 1 5.9% 2 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.27 17 9 52.9% 0 +[Q218R,T478R,F486S,A890V]-[T478K,F486P] (consensus) XBB.1.27 17 4 23.5% 1 +[T478R,F486S,A890V]-[T478K,F486P] XBB.1.27 17 1 5.9% 1 +[L5F,Q218R,T478R,F486S,A890V]-[T478K,F486P] XBB.1.27 17 1 5.9% 1 +[H146K,Q218R,T478R,F486S,A890V]-[H146Q,T478K,F486P] XBB.1.27 17 1 5.9% 1 +[Q218R,T478R,F486S,A890V]-[K417N,T478K,F486P] B.1.94 17 16 94.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.94 17 1 5.9% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.4.2 17 14 82.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.4.2 17 2 11.8% 1 +[M177I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.2 17 1 5.9% 1 +[G75S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.127 17 11 64.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.127 17 6 35.3% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.20 17 14 82.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,T299I,R403K,K444T,L452R,F486S,D1165G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.20 17 1 5.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T299I,R403K,K444T,L452R,F486S,D1165G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] CH.1.1.20 17 1 5.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T299I,K444T,L452R,F486S,D1165G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.20 17 1 5.9% 1 +[K147E,W152R,F157L,G181A,I210V,V213G,G257S,T299I,R403K,K444T,L452R,F486S,D1165G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FL.2.2 17 14 82.4% 0 +[T478R]-[T478K] (consensus) FL.2.2 17 1 5.9% 1 +[T478R]-[Y144-,T478K] FL.2.2 17 1 5.9% 1 +[T478R,N751T]-[T478K] FL.2.2 17 1 5.9% 1 +[T307I,T478R]-[T478K] FT.4 17 6 35.3% 0 +[E180Q,S704L] (consensus) FT.4 17 3 17.6% 2 +[E180Q,K1154N] FT.4 17 3 17.6% 1 +[E180Q] FT.4 17 1 5.9% 1 +[E180Q,V510L,S704L] FT.4 17 1 5.9% 2 +[E180Q,G1246S] EP.1 17 12 70.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) EP.1 17 2 11.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,Y266C,K356T,L452R,F486S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.1 17 1 5.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I,T791I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.1 17 1 5.9% 1 +[K147E,W152R,F157L,G181A,I210V,V213G,G257S,K356T,L452R,F486S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.1 17 1 5.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I,D936H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FL.1.7 17 13 76.5% 0 +[T478R,A701V,C1235F]-[T478K] (consensus) FL.1.7 17 2 11.8% 1 +[H146K,T478R,A701V,C1235F]-[H146Q,T478K] FL.1.7 17 1 5.9% 1 +[F157L,T478R,A701V,C1235F]-[T478K] FL.1.7 17 1 5.9% 2 +[F157L,T478R,A701V,C1235F]-[K417N,T478K] B.1.1.370 17 12 70.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.370 17 4 23.5% 1 +[D178N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.370 17 1 5.9% 1 +[A647S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GY.4 17 10 58.8% 0 +[E180V,N450K,T478R]-[T478K] (consensus) GY.4 17 2 11.8% 1 +[H146K,E180V,N450K,T478R]-[H146Q,T478K] GY.4 17 1 5.9% 2 +[E180V,N450K,T478R,P809S,D936N]-[T478K] GY.4 17 1 5.9% 8 +[H146K,E180V,N450K,T478R,D936N]-[H146Q,S371F,S373P,S375F,T376A,R408S,K417N,T478K] GY.4 17 1 5.9% 1 +[E180V,N450K,T478R,D1146Y]-[T478K] B.1.431 17 15 88.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.431 17 1 5.9% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.431 17 1 5.9% 1 +[W64R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.13 17 16 94.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.13 17 1 5.9% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.557 17 17 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) FL.13.3.1 17 17 100.0% 0 +[E154Q] (consensus) JP.1 17 6 35.3% 0 +[V36I,K147E,W152R,F157L,G181E,I210V,V213G,G257S,R403K,K444T,L452R,F486S,G1219V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,F486P,F490S] (consensus) JP.1 17 3 17.6% 1 +[V36I,K147E,W152R,F157L,G181E,I210V,V213G,G257S,R403K,K444T,L452R,F486S,G1219V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JP.1 17 1 5.9% 7 +[V36I,K147E,W152R,F157L,G181E,I210V,V213G,G257S,K444T,L452R,T478R,G1219V]-[V83A,Y144-,Q183E,V213E,G252V,T478K] JP.1 17 1 5.9% 2 +[V36I,K147E,W152R,F157L,G181E,I210V,V213G,G257S,R403K,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JP.1 17 1 5.9% 3 +[V36I,K147E,W152R,F157L,G181E,I210V,V213G,G257S,K444T,L452R,F486S,G1219V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.4.8 16 10 62.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.4.8 16 2 12.5% 1 +[V382L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.8 16 1 6.2% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.8 16 1 6.2% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.4.8 16 1 6.2% 1 +[A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.29 16 13 81.2% 0 +[Y449H,F565L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.29 16 1 6.2% 1 +[Y449H,N540S,F565L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] A.29 16 1 6.2% 4 +[N211-,L212I,A243S,Y449H,F565L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] A.29 16 1 6.2% 4 +[Y144F,L242-,A243-,L244-,Y449H,F565L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.444 16 14 87.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.444 16 2 12.5% 1 +[V70F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AG.1 16 11 68.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AG.1 16 3 18.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AG.1 16 1 6.2% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AG.1 16 1 6.2% 1 +[A1078V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.3 16 15 93.8% 0 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.438.3 16 1 6.2% 1 +[Q675H,I1114S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.45 16 11 68.8% 0 +[F486S]-[F486P] (consensus) XBB.1.45 16 4 25.0% 1 +[H146K,F486S]-[H146Q,F486P] XBB.1.45 16 1 6.2% 2 +[H146K,F486S]-[H146Q,K417N,F486P] B.6.2 16 15 93.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6.2 16 1 6.2% 1 +[D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.354 16 12 75.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.354 16 2 12.5% 1 +[H1088Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.354 16 1 6.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.354 16 1 6.2% 1 +[V16F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.445 16 16 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) FL.4.7 16 14 87.5% 0 +[L452R] (consensus) FL.4.7 16 1 6.2% 1 +[L452R]-[H146Q] FL.4.7 16 1 6.2% 1 +[H146K,L452R]-[H146Q] EW.3 16 12 75.0% 0 +[H69-,V70-,V213G,P251L,G339D,A348S,K444T,L452R,F486V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EW.3 16 2 12.5% 1 +[H69-,V70-,V213G,P251L,G339D,A348S,K444T,L452R,F486V,S494P,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EW.3 16 1 6.2% 1 +[H69-,V70-,V213G,P251L,G339D,A348S,K444T,V445F,L452R,F486V,N856S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EW.3 16 1 6.2% 1 +[H69-,V70-,V213G,P251L,G339D,A348S,K444T,L452R,F486V,N856S,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.42 16 15 93.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.42 16 1 6.2% 1 +[T719A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] N.2 16 15 93.8% 0 +[T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) N.2 16 1 6.2% 1 +[S659L,T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.112 16 12 75.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.112 16 3 18.8% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.112 16 1 6.2% 1 +[A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.19.2 16 10 62.5% 0 +[P521S] (consensus) XBB.1.19.2 16 2 12.5% 1 +[H245Y,P521S] XBB.1.19.2 16 1 6.2% 1 +[P521S,V1129I] XBB.1.19.2 16 1 6.2% 1 +[P521S,I1169T] XBB.1.19.2 16 1 6.2% 1 +[I128V,P521S] BY.1.1 16 6 37.5% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.1 16 3 18.8% 3 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.1 16 1 6.2% 5 +[K147E,W152R,F157L,V213G,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.1 16 1 6.2% 7 +[K147E,W152R,F157L,V213G,K356T,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.1 16 1 6.2% 4 +[H69-,V70-,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.1.1 16 8 50.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.1.1 16 2 12.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) EP.1.1 16 1 6.2% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,A348T,K356T,L452R,F486S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.1.1 16 1 6.2% 3 +[T22N,T76I,K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.1.1 16 1 6.2% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I,G1124A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DP.1 16 16 100.0% 0 +[H69-,V70-,V213G,G339D,A352S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) B.1.1.456 16 12 75.0% 0 +[E154Q,I834V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.456 16 3 18.8% 3 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.456 16 1 6.2% 2 +[E154Q,A522S,I834V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.296 16 16 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.386 16 13 81.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.386 16 1 6.2% 1 +[K1149R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.386 16 1 6.2% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.386 16 1 6.2% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.55 16 16 100.0% 0 +[L5F,Q1208H,S1252P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.262 16 7 43.8% 0 +[V622F,S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.262 16 6 37.5% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.262 16 3 18.8% 1 +[S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.47.1 16 12 75.0% 0 +[A260V,V1122G] (consensus) XBB.1.47.1 16 2 12.5% 1 +[A260V,A688V,V1122G] XBB.1.47.1 16 2 12.5% 1 +[L5F,A260V,V1122G] XCJ 16 8 50.0% 0 +[H146K,G181R,D253G,S494P,P521S]-[H146Q,G252V] (consensus) XCJ 16 4 25.0% 2 +[G181R,D253G,P521S]-[G252V] XCJ 16 2 12.5% 1 +[H146K,G181R,D253G,N481T,S494P,P521S]-[H146Q,G252V] XCJ 16 1 6.2% 5 +[G181P,D253G,S254F,K444T,S494P,P521S,P812S]-[G252V] XCJ 16 1 6.2% 3 +[G181R,G232S,D253G,P521S]-[G252V] JN.3.2 16 5 31.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3.2 16 5 31.2% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3.2 16 4 25.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.3.2 16 1 6.2% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,F486S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] JN.3.2 16 1 6.2% 12 +[+16MPLF,R21T,S50L,V62-,T63-,W64-,F65-,H66-,A67-,I68-,H69-,V70-,S71-,N74-,G75-,T76-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] AJ.1 15 14 93.3% 0 +[M153I,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AJ.1 15 1 6.7% 1 +[M153I,A570D,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.358 15 7 46.7% 0 +[R21T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.358 15 3 20.0% 1 +[R21T,A623S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.358 15 1 6.7% 1 +[R21T,S929I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.358 15 1 6.7% 1 +[R21T,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.358 15 1 6.7% 1 +[R21T,H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.34 15 15 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) BW.1.2 15 15 100.0% 0 +[H69-,V70-,V213G,G339D,R346S,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) B.1.145 15 10 66.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.145 15 1 6.7% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.145 15 1 6.7% 1 +[K795Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.145 15 1 6.7% 1 +[I434V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.145 15 1 6.7% 1 +[E156D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.48.1 15 10 66.7% 0 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.48.1 15 2 13.3% 1 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.48.1 15 1 6.7% 4 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.48.1 15 1 6.7% 5 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.48.1 15 1 6.7% 1 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.7.3 15 10 66.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.7.3 15 2 13.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.7.3 15 1 6.7% 25 +[S50L,H69-,V70-,V127F,F157S,R158G,V445I,F456L,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V445P,G446S,F490S,P681H] JN.1.7.3 15 1 6.7% 27 +[S50L,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,P681H] JN.1.7.3 15 1 6.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.258.23 15 13 86.7% 0 +[H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.23 15 1 6.7% 1 +[H69-,V70-,L189F,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.23 15 1 6.7% 4 +[V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.8.1 15 8 53.3% 0 -[G252V] (consensus) XBB.8.1 15 3 20.0% 1 +[H146K]-[H146Q,G252V] XBB.8.1 15 1 6.7% 1 -[G252V,K417N] XBB.8.1 15 1 6.7% 7 +[D178-,L179-,E180-,K182-,Q183-,G184-,T385I]-[Q183E,G252V] XBB.8.1 15 1 6.7% 4 +[H146K]-[H146Q,G252V,R408S,S477N,Q954H] AQ.1 15 13 86.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AQ.1 15 1 6.7% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AQ.1 15 1 6.7% 2 +[L5F,S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.66 15 12 80.0% 0 +[L18F,D215H,A222V,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.66 15 2 13.3% 1 +[L18F,D215H,A222V,A694S,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.66 15 1 6.7% 1 +[L18F,D215H,A222V,L1063F,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBC.1.7 15 7 46.7% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,T299I,K444T,L452M,T478R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,T478K,F490S] (consensus) XBC.1.7 15 3 20.0% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,K444T,L452M,T478R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,T478K,F490S] XBC.1.7 15 2 13.3% 1 +[P25S,E156G,F157-,R158-,P174S,P209L,L212S,D215H,A222V,A243-,L244-,S256L,T299I,K444T,L452M,T478R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,T478K,F490S] XBC.1.7 15 1 6.7% 2 +[P25S,E156G,F157-,R158-,P174S,P209L,L212S,D215H,A222V,A243-,L244-,S256L,T299I,K444T,L452M,T478R,N703I,L1224F]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,T478K,F490S] XBC.1.7 15 1 6.7% 4 +[P25S,T95I,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,K444T,L452M,T478R,N703I]-[L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,T478K,F490S] XBC.1.2 15 14 93.3% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,L216F,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.2 15 1 6.7% 1 +[V6A,P25S,E156G,F157-,R158-,P209L,L212S,D215H,L216F,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] JH.1 15 5 33.3% 0 +[H69-,V70-,K147E,K182E,V213G,P251L,G339D,K444T,V445A,L452R,F486A,S494P,E554K,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) JH.1 15 3 20.0% 1 +[H69-,V70-,K147E,K182E,V213G,P251L,G339D,K444T,V445A,L452R,F486A,S494P,E554K,I666V,D1259Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] JH.1 15 2 13.3% 1 +[H69-,V70-,K77N,K147E,K182E,V213G,P251L,G339D,K444T,V445A,L452R,F486A,S494P,E554K,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] JH.1 15 1 6.7% 2 +[H69-,V70-,K147E,K182E,N185D,V213G,P251L,G339D,K444T,V445A,L452R,F486A,S494P,E554K,I666V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] JH.1 15 1 6.7% 1 +[H69-,V70-,K147E,K182E,N185D,V213G,P251L,G339D,K444T,V445A,L452R,F486A,S494P,E554K,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FW.3 15 9 60.0% 0 +[K356T,R403K,F486S]-[F486P] (consensus) FW.3 15 2 13.3% 1 +[K356T,R403K,F486S,T961M]-[F486P] FW.3 15 2 13.3% 1 +[K356T,R403K,F486S,A1078S]-[F486P] FW.3 15 1 6.7% 1 +[Q14H,K356T,R403K,F486S]-[F486P] FW.3 15 1 6.7% 2 +[L216F,K356T,R403K,F486S,S494P]-[F486P] FL.1.1.1 15 12 80.0% 0 +[A688S,A701V] (consensus) FL.1.1.1 15 1 6.7% 2 +[A688S,A701V]-[T19I,H146Q] FL.1.1.1 15 1 6.7% 6 +[A688S,A701V]-[G142D,Y144-,H146Q,Q183E,N764K,D796Y] FL.1.1.1 15 1 6.7% 7 +[A688S,A701V]-[T19I,V83A,G142D,Y144-,H146Q,Q183E,D796Y] FT.2 15 11 73.3% 0 +[K1045N] (consensus) FT.2 15 2 13.3% 1 +[L5F,K1045N] FT.2 15 1 6.7% 1 +[S943G,K1045N] FT.2 15 1 6.7% 1 +[K1045N]-[V83A] XBB.5 15 8 53.3% 0 +[F486S,A653V]-[G252V,F486P] (consensus) XBB.5 15 6 40.0% 1 +[F486S,A653V]-[T19I,G252V,F486P] XBB.5 15 1 6.7% 1 +[F486S,A653V]-[V83A,G252V,F486P] EV.1 15 15 100.0% 0 +[H69-,V70-,K182E,V213G,Y248H,P251L,G339D,K444T,G446R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) FN.1 15 8 53.3% 0 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] (consensus) FN.1 15 7 46.7% 1 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,T478R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,T478K,F486P,F490S] XBF.1 15 9 60.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF.1 15 2 13.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,R357I,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.1 15 2 13.3% 1 +[K147E,W152R,F157L,L176F,I210V,V213G,G257S,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.1 15 1 6.7% 2 +[L141F,K147E,W152R,F157L,I210V,V213G,G257S,E619Q,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF.1 15 1 6.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,Y505H] B.1.363 15 8 53.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.363 15 2 13.3% 2 +[E583D,A892V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.363 15 2 13.3% 2 +[T716I,A892V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.363 15 2 13.3% 1 +[A892V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.363 15 1 6.7% 1 +[Q1208R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBC.1.1.1 15 13 86.7% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,G476-,T478N,+478K,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,S477N,T478K,F490S] (consensus) XBC.1.1.1 15 2 13.3% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,G476-,T478N,+478K,N703I,I805M]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,S477N,T478K,F490S] XDD.2 15 10 66.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDD.2 15 2 13.3% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD.2 15 1 6.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,I569S,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD.2 15 1 6.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,Q607H,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDD.2 15 1 6.7% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,P479L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V860L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.425 15 15 100.0% 0 +[V62I,D867G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.184 15 14 93.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.184 15 1 6.7% 1 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] M.3 15 13 86.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) M.3 15 2 13.3% 1 +[A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.22 15 8 53.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.22 15 5 33.3% 1 +[A1174V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.22 15 1 6.7% 2 +[A653V,A1174V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.22 15 1 6.7% 3 +[R408K,I410N,A1174V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.7 15 9 60.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.7 15 2 13.3% 1 +[H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.7 15 1 6.7% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.7 15 1 6.7% 1 +[D1146V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.7 15 1 6.7% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.31 15 8 53.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.31 15 1 6.7% 1 +[D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.31 15 1 6.7% 2 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.31 15 1 6.7% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.31 15 1 6.7% 1 +[A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.421 15 11 73.3% 0 +[G769V,V1104I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.421 15 2 13.3% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.421 15 1 6.7% 1 +[L335F,G769V,V1104I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.421 15 1 6.7% 1 +[G769V,V1104I,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.52 15 12 80.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.52 15 1 6.7% 1 +[A845V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.52 15 1 6.7% 1 +[Q1071H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.52 15 1 6.7% 1 +[G181V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.8.1 15 13 86.7% 0 +[L5F,H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.8.1 15 1 6.7% 2 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.8.1 15 1 6.7% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.1.23 15 6 40.0% 0 +[A67V,H69-,V70-,T95I,E96D,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,L455W,K458M,E484V,Q493R,G496S,T547K,P681R,A688V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,T376A,D405N,R408S,V445P,N460K,E484A,F486P,F490S,P681H] (consensus) BA.1.23 15 2 13.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,K458M,E484V,Q493R,G496S,T547K,A688V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,T376A,D405N,R408S,V445P,N460K,E484A,F486P,F490S] BA.1.23 15 1 6.7% 1 +[A67V,H69-,V70-,T95I,E96D,V143-,Y145-,N211-,L212I,+214EPE,G339D,L455W,K458M,E484V,Q493R,G496S,T547K,P681R,A688V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,T376A,D405N,R408S,V445P,N460K,E484A,F486P,F490S,P681H] BA.1.23 15 1 6.7% 7 +[A67V,H69-,V70-,T95I,E96D,V143-,Y145-,N211-,L212I,+214EPE,S254F,G339D,N448S,L455W,F456L,E484V,Q493R,G496S,T547K,P681R,A688V,N856K,S982L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,T376A,D405N,R408S,V445P,N460K,E484A,F486P,F490S,P681H] BA.1.23 15 1 6.7% 1 +[A67V,H69-,V70-,T95I,E96D,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,V445A,L455W,K458M,E484V,Q493R,G496S,T547K,P681R,A688V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,T376A,D405N,R408S,V445P,N460K,E484A,F486P,F490S,P681H] B.1.1.88 15 15 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.29 14 11 78.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.29 14 2 14.3% 2 +[A845S,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.29 14 1 7.1% 1 +[V622A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.2 14 11 78.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.2 14 1 7.1% 1 +[R78M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.2 14 1 7.1% 1 +[R102I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.2 14 1 7.1% 1 +[L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.6 14 10 71.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5.6 14 1 7.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,E1195Q]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.6 14 1 7.1% 1 +[T19R,E156G,F157-,R158-,A419S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.6 14 1 7.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,E1207D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.6 14 1 7.1% 1 +[T19R,T20I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XDV 14 5 35.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDV 14 4 28.6% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDV 14 2 14.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,D215Y,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDV 14 2 14.3% 6 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1200I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDV 14 1 7.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XAY 14 14 100.0% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] (consensus) XBV 14 8 57.1% 0 +[F486S,P521T,E554G,I870V]-[F486P] (consensus) XBV 14 4 28.6% 1 +[H146K,F486S,P521T,E554G,I870V]-[H146Q,F486P] XBV 14 1 7.1% 1 +[P521T,E554G,I870V]-[F486P] XBV 14 1 7.1% 15 +[H146K,F486S,P521T,E554G,P681R,I870V]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,R408S,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K] B.1.429.1 14 14 100.0% 0 +[S13I,W152C,L452R,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.450 14 14 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.34 14 11 78.6% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.34 14 1 7.1% 1 +[S98F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.34 14 1 7.1% 1 +[A222V,V510I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.34 14 1 7.1% 2 +[A222V,Y449H,S477G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JH.2 14 5 35.7% 0 +[H69-,V70-,K147E,F186Y,K187-,N188-,V213G,G339D,K444T,V445A,L452R,E484K,F486A,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) JH.2 14 3 21.4% 2 +[H69-,V70-,K147E,F186Y,K187-,N188-,V213G,P217L,G339D,K444T,V445A,L452R,E484K,F486A,T547I,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,E484A,F486P,F490S] JH.2 14 3 21.4% 1 +[T19L,H69-,V70-,K147E,F186Y,K187-,N188-,V213G,G339D,K444T,V445A,L452R,E484K,F486A,I666V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,E484A,F486P,F490S] JH.2 14 1 7.1% 3 +[H69-,V70-,K147E,F186Y,K187-,N188-,V213G,S254F,G339D,K444T,V445A,L452R,E484K,F486A,I666V,K1149R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,E484A,F486P,F490S] JH.2 14 1 7.1% 3 +[K147E,F186Y,K187-,N188-,V213G,S254F,G339D,K444T,V445A,L452R,E484K,F486A,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,E484A,F486P,F490S] B.1.1.341 14 14 100.0% 0 +[D178N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.178 14 10 71.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.178 14 2 14.3% 1 +[P479S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.178 14 1 7.1% 2 +[S112L,V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.178 14 1 7.1% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.4 14 14 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.190 14 7 50.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.190 14 5 35.7% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.190 14 2 14.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.18 14 8 57.1% 0 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] (consensus) A.18 14 4 28.6% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.18 14 1 7.1% 3 +[V213L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.18 14 1 7.1% 5 +[L5F,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.76.1 14 13 92.9% 0 +[V213G,Y248N,G339D,R357K,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.76.1 14 1 7.1% 1 +[L5F,V213G,Y248N,G339D,R357K,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.87 14 12 85.7% 0 +[G1171V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.87 14 1 7.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.87 14 1 7.1% 1 +[C15F,G1171V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XCF.1 14 14 100.0% 0 +[F157L,F456L] (consensus) B.1.511 13 10 76.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.511 13 3 23.1% 1 +[T307N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.20 13 10 76.9% 0 +[F486S]-[F486P] (consensus) XBB.1.20 13 1 7.7% 3 +[F486S,H519L]-[Y144-,H146Q,F486P] XBB.1.20 13 1 7.7% 4 +[V143D,Y144Q,Y145-,H146-,F486S]-[Y144-,H146Q,F486P] XBB.1.20 13 1 7.7% 1 +[F486S]-[Y144-,F486P] B.1.292 13 12 92.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.292 13 1 7.7% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.158 13 10 76.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.158 13 2 15.4% 2 +[A684V,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.158 13 1 7.7% 1 +[S50L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.25.1 13 11 84.6% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.25.1 13 1 7.7% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] JN.1.25.1 13 1 7.7% 18 +[F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,V445H,E554K,A570V,P621S,P681R,S939F,P1143L,S1170F]-[H146Q,Q183E,V213E,G252V,L368I,V445P,F490S,P681H] BQ.1.15.2 13 9 69.2% 0 +[H69-,V70-,G181V,V213G,Y248S,+248DAD,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.15.2 13 3 23.1% 1 +[H69-,V70-,V213G,Y248S,+248DAD,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.15.2 13 1 7.7% 7 +[H69-,V70-,Y200C,V213G,Y248S,+248DAD,G339D,K444T,V445F,L452R,E484V,F486V,N703D,P1143S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] B.1.1.149 13 13 100.0% 0 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.114 13 13 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.350 13 12 92.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.350 13 1 7.7% 2 +[T299I,T323I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.483 13 12 92.3% 0 +[V6F,D198G,A845S,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.483 13 1 7.7% 1 +[V6F,D198G,A845S,T859I,N1187I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GD.3 13 5 38.5% 0 +[F59L,F486S]-[F486P] (consensus) GD.3 13 2 15.4% 3 +[F59L,F486S,E1202Q]-[R408S,F486P,D796Y] GD.3 13 1 7.7% 1 +[F59L,F486S]-[Y144-,F486P] GD.3 13 1 7.7% 3 +[F59L,G257S,F486S,Q804K]-[G252V,F486P] GD.3 13 1 7.7% 2 +[F59L,F486S]-[R408S,F486P,D796Y] BQ.1.2.2 13 4 30.8% 0 +[H69-,V70-,K147E,F186Y,K187-,N188-,V213G,G339D,K444T,V445A,L452R,F486V,I666V,N703Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.2.2 13 2 15.4% 2 +[H69-,V70-,K147E,N149D,F186Y,K187-,N188-,V213G,G339D,K444T,V445A,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.2.2 13 2 15.4% 9 +[H69-,V70-,K147E,K182E,V213G,L249S,G339D,K444T,V445A,L452R,F486A,S494P,E554K,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.2.2 13 1 7.7% 2 +[H69-,V70-,K147E,F186Y,K187-,N188-,V213G,G339D,K444T,V445A,L452R,F486V,I666V,N703Y,A1222R,L1224F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.2.2 13 1 7.7% 11 +[H69-,V70-,K147E,K182E,N185D,V213G,P251L,G339D,K444T,V445A,L452R,F486A,S494P,E554K,I666V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CH.1.1.31 13 10 76.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.31 13 2 15.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.31 13 1 7.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,I1210V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CM.7.1 13 9 69.2% 0 +[K147E,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.7.1 13 1 7.7% 2 +[K147E,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,G485V,F486S,P807S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.7.1 13 1 7.7% 2 +[T109I,K147E,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,I834T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.7.1 13 1 7.7% 1 +[K147E,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E471Q,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.7.1 13 1 7.7% 1 +[K147E,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,K854N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] XBY 13 13 100.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) B.6.5 13 11 84.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6.5 13 2 15.4% 1 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362.1 13 11 84.6% 0 +[A684V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.362.1 13 2 15.4% 1 +[A684V,P1079S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.16 13 11 84.6% 0 +[T73I,A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.16 13 2 15.4% 1 +[A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.83 13 8 61.5% 0 +[P9T,W64R,H69-,V70-,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,V213G,R214L,A243-,L244-,G252D,G339D,R1091H,V1264L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,T478K,F486P,F490S] (consensus) BA.2.83 13 1 7.7% 1 +[P9T,W64R,H69-,V70-,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,V213G,R214L,A243-,L244-,G252D,G339D,L452R,R1091H,V1264L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,T478K,F486P,F490S] BA.2.83 13 1 7.7% 18 +[P9T,W64R,V213G,R214L,G252D,G339D,K444M,L452R,R1091H,V1264L]-[L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,T478K,F486P,F490S] BA.2.83 13 1 7.7% 1 +[P9T,W64R,H69-,V70-,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,V213G,R214L,A243-,L244-,G339D,R1091H,V1264L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,T478K,F486P,F490S] BA.2.83 13 1 7.7% 1 +[P9T,W64R,H69-,V70-,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,G181A,V213G,R214L,A243-,L244-,G252D,G339D,R1091H,V1264L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,T478K,F486P,F490S] DD.1 13 9 69.2% 0 +[P9L,H69-,V70-,G339N,Y449N,N481K,Q493L,K1205N]-[V83A,H146Q,Q183E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DD.1 13 1 7.7% 1 +[P9L,H69-,V70-,G339N,Y449N,N481K,Q493L,K1205N]-[V83A,G142D,H146Q,Q183E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DD.1 13 1 7.7% 1 +[P9L,H69-,V70-,G339N,A435S,Y449N,N481K,Q493L,K1205N]-[V83A,H146Q,Q183E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DD.1 13 1 7.7% 1 +[P9L,H69-,V70-,L179R,G339N,Y449N,N481K,Q493L,K1205N]-[V83A,H146Q,Q183E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DD.1 13 1 7.7% 3 +[P9L,H69-,V70-,G339N,Y449N,N481K,Q493L,A879V,K1205N]-[V83A,G142D,H146Q,Q183E,G252V,G339H,L368I,N440K,V445P,G446S,F486P,F490S] CR.1.2 13 12 92.3% 0 +[H69-,V70-,V213G,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CR.1.2 13 1 7.7% 1 +[H69-,V70-,V213G,T250I,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.184 13 3 23.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.184 13 2 15.4% 1 +[H1083Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.184 13 2 15.4% 3 +[L7S,A701T,H1083Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.184 13 2 15.4% 3 +[A701T,P812L,H1083Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.184 13 1 7.7% 2 +[P812L,H1083Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.26 13 13 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.168 13 13 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.9.1 13 12 92.3% 0 +[F1121L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.9.1 13 1 7.7% 1 +[F1121L,M1233I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.198 13 11 84.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.198 13 2 15.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.7 13 7 53.8% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,G594S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.7 13 4 30.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,G594S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.7 13 2 15.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,K150E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,E484K,E554K,A570V,G594S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KZ.1.1.1 13 9 69.2% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KZ.1.1.1 13 2 15.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1122L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KZ.1.1.1 13 2 15.4% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680-,+683R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] BP.1 13 8 61.5% 0 +[H69-,V70-,V213G,G339D,R403K,L452M,Q493R,A570V,Q762E,A852V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BP.1 13 3 23.1% 1 +[H69-,V70-,V213G,T240I,G339D,R403K,L452M,Q493R,A570V,Q762E,A852V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BP.1 13 1 7.7% 1 +[H69-,V70-,K147E,V213G,G339D,R403K,L452M,Q493R,A570V,Q762E,A852V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BP.1 13 1 7.7% 1 +[H69-,V70-,V213G,G339D,R403K,L452M,A475V,Q493R,A570V,Q762E,A852V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] C.5 12 11 91.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.5 12 1 8.3% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.481 12 11 91.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.481 12 1 8.3% 1 +[K77N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] V.2 12 12 100.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.5 12 12 100.0% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] (consensus) CH.3 12 10 83.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] (consensus) CH.3 12 1 8.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F490L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] CH.3 12 1 8.3% 5 +[K147E,W152R,F157L,I210V,V213G,G257S,F490L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S] B.1.1.110 12 5 41.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.110 12 2 16.7% 1 +[L1244F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.110 12 2 16.7% 2 +[S254F,T299I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.110 12 1 8.3% 1 +[T299I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.110 12 1 8.3% 2 +[E309Q,P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HC.4 12 6 50.0% 0 +[K356T,T572I,D1084H] (consensus) HC.4 12 2 16.7% 1 +[H146K,K356T,T572I,D1084H]-[H146Q] HC.4 12 1 8.3% 1 +[K356T,T393I,T572I,D1084H] HC.4 12 1 8.3% 2 +[W258L,K356T,T572I,A1078S,D1084H] HC.4 12 1 8.3% 3 +[H146K,A243S,K356T,L517F,T572I,D1084H]-[H146Q] B.1.1.411 12 6 50.0% 0 +[S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.411 12 4 33.3% 2 +[T19R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.411 12 1 8.3% 2 +[T19R,I870S,S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.411 12 1 8.3% 1 +[A771V,S943P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.32.1 12 5 41.7% 0 +[N450D,Y453F,F486S]-[F486P] (consensus) XBB.1.32.1 12 2 16.7% 1 +[N450D,Y453F,F486S,Q607H]-[F486P] XBB.1.32.1 12 1 8.3% 1 +[N450D,Y453F,F486S,P793S]-[F486P] XBB.1.32.1 12 1 8.3% 2 +[Y453F,F486S]-[G142D,F486P] XBB.1.32.1 12 1 8.3% 2 +[Y453F,F486S]-[K417N,F486P] XBB.1.14.1 12 10 83.3% 0 +[G75V,N148T,F486S,E554K]-[F486P] (consensus) XBB.1.14.1 12 1 8.3% 1 +[G75V,N148T,F486S,E554K,G1124D]-[F486P] XBB.1.14.1 12 1 8.3% 4 +[G75V,N148T,F486S,R682Q]-[R408S,F486P,D796Y] B.1.1.202 12 12 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.50 12 12 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.24.2 12 10 83.3% 0 +[R158S] (consensus) XBB.1.24.2 12 1 8.3% 1 +[R158S,L176F] XBB.1.24.2 12 1 8.3% 1 +[R158S]-[G142D] B.1.1.330 12 12 100.0% 0 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) BN.1.5.1 12 6 50.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S514T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.5.1 12 4 33.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S514T]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.5.1 12 1 8.3% 1 +[L54F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,S514T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.5.1 12 1 8.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S514T,P1263L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.1.166 12 9 75.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.166 12 1 8.3% 2 +[L242F,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.166 12 1 8.3% 1 +[L242F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.166 12 1 8.3% 1 +[L229F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.338 12 6 50.0% 0 +[G485R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.338 12 5 41.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.338 12 1 8.3% 2 +[H519Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.30 12 11 91.7% 0 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.30 12 1 8.3% 1 +[R21I,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.155 12 12 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.1 12 6 50.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.1 12 1 8.3% 3 +[E309Q,A570V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.1 12 1 8.3% 2 +[E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.1 12 1 8.3% 1 +[K1181N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.1 12 1 8.3% 1 +[I468V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.249 12 12 100.0% 0 +[P251L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) BY.1.2.1 12 9 75.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BY.1.2.1 12 2 16.7% 1 +[K147E,W152R,M153T,F157L,I210V,V213G,G257S,F486S,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1.2.1 12 1 8.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S494P,T1238I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] C.1.1 11 7 63.6% 0 +[A688-,+689R,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.1.1 11 2 18.2% 3 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.1.1 11 1 9.1% 4 +[P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.1.1 11 1 9.1% 4 +[C1236S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.18 11 8 72.7% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.18 11 2 18.2% 1 +[H69-,V70-,N439K,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.18 11 1 9.1% 1 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] XAY.1.2 11 9 81.8% 0 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] (consensus) XAY.1.2 11 1 9.1% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S,P681H] XAY.1.2 11 1 9.1% 1 +[L18F,T19R,R21G,T95I,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,V445A,G446D,L452R,P621S,A706V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F490S] C.20 11 10 90.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.20 11 1 9.1% 1 +[V483L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.3.2.1 11 6 54.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.3.2.1 11 2 18.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3.2.1 11 1 9.1% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3.2.1 11 1 9.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S698L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.3.2.1 11 1 9.1% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376V,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] B.1.1.182 11 9 81.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.182 11 2 18.2% 1 +[T573I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EP.1.1.1 11 6 54.5% 0 +[T22N,T76I,K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I,T1006A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) EP.1.1.1 11 2 18.2% 1 +[T22N,T76I,K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I,T1006A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P,F490S] EP.1.1.1 11 1 9.1% 1 +[T22N,T76I,K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,F486S,T572I,P631S,T1006A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EP.1.1.1 11 1 9.1% 5 +[T22N,T76I,K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R,T572I,T1006A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,Q498R,N501Y,Y505H] EP.1.1.1 11 1 9.1% 2 +[T22N,T76I,K147E,W152R,F157L,I210V,V213G,H245Y,G257S,K356T,L452R,F486S,T572I,T1006A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,F486P,F490S] GA.6.1 11 7 63.6% 0 +[D215H,T250I,T478R]-[T478K] (consensus) GA.6.1 11 1 9.1% 1 +[D215H,T250I,T478R,A879V]-[T478K] GA.6.1 11 1 9.1% 1 +[D215H,T250I,T478R]-[N460K,T478K] GA.6.1 11 1 9.1% 1 +[T250I,T478R]-[T478K] GA.6.1 11 1 9.1% 1 +[D215H,T250I,T478R]-[K417N,T478K] XBB.2.7.1 11 4 36.4% 0 +[D253G,Y453F,T478Q,F486S]-[G252V,T478K,F486P] (consensus) XBB.2.7.1 11 2 18.2% 2 +[D253G,P272L,Y453F,T478Q,F486S,E1017D]-[G252V,T478K,F486P] XBB.2.7.1 11 1 9.1% 16 +[D253G,Y453F,T478Q,F486S]-[L24-,P25-,P26-,A27S,Y144-,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,N460K,T478K,F486P,N679K,P681H,N764K] XBB.2.7.1 11 1 9.1% 1 +[H146K,D253G,Y453F,T478Q,F486S]-[H146Q,G252V,T478K,F486P] XBB.2.7.1 11 1 9.1% 1 +[D253G,Y453F,T478Q,F486S]-[G252V,K417N,T478K,F486P] B.1.502 11 11 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.364 11 9 81.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.364 11 2 18.2% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.21 11 1 9.1% 0 +[P9L,H245N,T299I,G339D,K444T,L455A,Q493L]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.21 11 1 9.1% 8 +[P9L,V213G,G339D,A570T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.3.21 11 1 9.1% 7 +[P9L,V213G,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.21 11 1 9.1% 8 +[P9L,R21I,V213G,T299I,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P] BA.2.3.21 11 1 9.1% 8 +[P9L,V213G,D215G,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] A.17 11 11 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.9.2 11 10 90.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.9.2 11 1 9.1% 1 +[S13I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.249 11 11 100.0% 0 +[G257D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.38 11 9 81.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.38 11 1 9.1% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.38 11 1 9.1% 2 +[D138H,P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.640.2 11 5 45.5% 0 +[P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,D215H,R346S,N394S,Y449N,E484K,T859N,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.640.2 11 3 27.3% 1 +[L5F,P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,D215H,R346S,N394S,Y449N,E484K,T859N,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.640.2 11 1 9.1% 1 +[P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,D215H,R346S,N394S,Y449N,E484K,T859N,D1139H,K1181N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.640.2 11 1 9.1% 1 +[P9L,E96Q,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,R190S,D215H,R346S,N394S,Y449N,E484K,S704L,T859N,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.640.2 11 1 9.1% 9 +[P9L,E96Q,V143-,Y145-,R190S,D215H,R346S,N394S,Y449N,E484K,S704L,T859N,D1139H]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BM.1.1.2 11 11 100.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,T883I,S939F,P1079T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) B.1.1.185 11 9 81.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.185 11 1 9.1% 2 +[P9L,E1150D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.185 11 1 9.1% 1 +[T208A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.11 10 9 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.11 10 1 10.0% 3 +[E654A,H655D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KP.1.2 10 4 40.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KP.1.2 10 2 20.0% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,F1103L,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KP.1.2 10 1 10.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] KP.1.2 10 1 10.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KP.1.2 10 1 10.0% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.110.1 10 8 80.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.110.1 10 1 10.0% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110.1 10 1 10.0% 1 +[T676S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.16.2 10 5 50.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.16.2 10 3 30.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,N978T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.16.2 10 1 10.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.16.2 10 1 10.0% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.423 10 8 80.0% 0 +[H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.423 10 1 10.0% 1 +[P384S,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.423 10 1 10.0% 1 +[E406Q,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.22 10 8 80.0% 0 +[H69-,V70-,W152L,N211-,L212I,V213G,S255F,G339D,K417T,F490A,Q493R,A942S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,N440K,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.22 10 2 20.0% 2 +[H69-,V70-,W152L,N211-,L212I,V213G,S255F,G339D,K417T,F490A,Q493R,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] DB.3 10 9 90.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DB.3 10 1 10.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,V1060I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.531 10 9 90.0% 0 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.531 10 1 10.0% 1 +[A879S,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.34.2 10 6 60.0% 0 +[H146K,K182I,P681R]-[H146Q,P681H] (consensus) XBB.1.34.2 10 2 20.0% 1 +[H146K,K182I,F456L,P681R]-[H146Q,P681H] XBB.1.34.2 10 1 10.0% 2 +[H146K,S151I,K182I,P681R,I997V]-[H146Q,P681H] XBB.1.34.2 10 1 10.0% 1 +[K182I,P681R]-[P681H] HD.1.1 10 4 40.0% 0 +[R346I,K356T]-[R346T] (consensus) HD.1.1 10 4 40.0% 1 +[R346I,K356T]-[R346T,K417N] HD.1.1 10 1 10.0% 2 +[R346I,K356T,E554Q]-[R346T,K417N] HD.1.1 10 1 10.0% 1 +[R346I,K356T,T572I]-[R346T] CZ.1 10 9 90.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,F490I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) CZ.1 10 1 10.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,F490I]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.12 10 5 50.0% 0 +[Y453F,F486S]-[F486P] (consensus) XBB.1.12 10 2 20.0% 1 +[Y453F,A475V,F486S]-[F486P] XBB.1.12 10 1 10.0% 3 +[R190S,Y453F,F486S]-[R408S,N460K,F486P] XBB.1.12 10 1 10.0% 1 +[Y453F,F486S,N856S]-[F486P] XBB.1.12 10 1 10.0% 1 +[D178N,Y453F,F486S]-[F486P] CH.3.1 10 8 80.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] (consensus) CH.3.1 10 2 20.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,S494P,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] B.1.192 10 9 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.192 10 1 10.0% 2 +[G769V,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.175 10 7 70.0% 0 +[N211Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.175 10 2 20.0% 1 +[N211Y,T236S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.175 10 1 10.0% 1 +[N211Y,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BM.2.3 10 3 30.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.2.3 10 1 10.0% 2 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,F486I,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.2.3 10 1 10.0% 11 +[K147E,F486I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.2.3 10 1 10.0% 7 +[W152R,I210V,G257S,F486I]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.2.3 10 1 10.0% 2 +[K97Q,K147E,W152R,F157L,I210V,V213G,G257S,T478I,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,F486P,F490S] B.1.490 10 6 60.0% 0 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.490 10 4 40.0% 1 +[L5F,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JB.2.1 10 6 60.0% 0 +[F140I,H245Y,R403K,T478R,E554D,L582F]-[T478K] (consensus) JB.2.1 10 2 20.0% 1 +[F140I,H245Y,R403K,T478R,E554D,L582F,Q613H]-[T478K] JB.2.1 10 1 10.0% 3 +[I68T,F140I,H245Y,R403K,T478R,T500A,E554D,L582F,D936N]-[T478K] JB.2.1 10 1 10.0% 1 +[F140I,H245Y,R403K,T478R,T500A,E554D,L582F]-[T478K] FL.18.1.1 10 6 60.0% 0 +[Y200C,T478R]-[T478K] (consensus) FL.18.1.1 10 1 10.0% 10 +[Y200C,S704L,G1219C]-[S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H] FL.18.1.1 10 1 10.0% 1 +[Y200C,D427G,T478R]-[T478K] FL.18.1.1 10 1 10.0% 1 +[Y200C,T478R,S704L]-[T478K] FL.18.1.1 10 1 10.0% 3 +[Y200C,G339R,T478R,T572I,V1228L]-[G339H,T478K] EG.12 10 4 40.0% 0 +[H146K,E554K]-[H146Q] (consensus) EG.12 10 3 30.0% 1 +[H146K,K182N,E554K]-[H146Q] EG.12 10 1 10.0% 2 +[H146K,S494P,E554K]-[Y144-,H146Q] EG.12 10 1 10.0% 2 +[Y145K,H146K,E554K]-[Y144-,H146Q] EG.12 10 1 10.0% 1 +[H146K,S494P,E554K]-[H146Q] JB.2 10 3 30.0% 0 +[F140I,R403K,T478R,L582F]-[T478K] (consensus) JB.2 10 3 30.0% 1 +[F140I,R403K,T478R,L582F,T732I]-[T478K] JB.2 10 2 20.0% 2 +[F140I,H146K,G181V,R403K,T478R,L582F]-[H146Q,T478K] JB.2 10 1 10.0% 1 +[F140I,R403K,T478R,L582F]-[Y144-,T478K] JB.2 10 1 10.0% 1 +[F140I,R403K,T478R,L582F,E583D]-[T478K] B.1.1.463 10 10 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.24 10 6 60.0% 0 +[D614A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.24 10 2 20.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.24 10 2 20.0% 2 +[L452M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.160 10 10 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.154 10 9 90.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.154 10 1 10.0% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BL.1.2 10 9 90.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,G261D,V308L,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BL.1.2 10 1 10.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G261D,V308L,T315I,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.357 9 9 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) GW.3 9 4 44.4% 0 +[E554K] (consensus) GW.3 9 2 22.2% 3 +[E132K,P330S,E554K,K1073N] GW.3 9 2 22.2% 1 +[S71F,E554K] GW.3 9 1 11.1% 2 -[H146Q] XDT 9 4 44.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDT 9 2 22.2% 1 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDT 9 1 11.1% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218H,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDT 9 1 11.1% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XDT 9 1 11.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.111 9 9 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AM.2 9 9 100.0% 0 +[D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) BA.2.75.9 9 7 77.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BA.2.75.9 9 1 11.1% 8 +[K147E,W152R,F157L,I210V,F486S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.9 9 1 11.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] JQ.2 9 4 44.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JQ.2 9 3 33.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JQ.2 9 1 11.1% 3 +[+16MPLF,R21T,S50L,H69-,V70-,G75V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,D614G,P681H] JQ.2 9 1 11.1% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] B.1.194 9 4 44.4% 0 +[D1146H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.194 9 2 22.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.194 9 2 22.2% 1 +[M1050L,D1146H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.194 9 1 11.1% 1 +[T95I,D1146H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BL.5 9 8 88.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,R346S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BL.5 9 1 11.1% 3 +[K147E,W152R,F157L,I210V,V213G,G257S,R346S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,S477N,T478K,F486P,F490S] B.1.1.401 9 8 88.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.401 9 1 11.1% 1 +[K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.49 9 7 77.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.49 9 2 22.2% 1 +[E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.4.1.1 9 7 77.8% 0 +[N450I,T478R]-[T478K] (consensus) FL.4.1.1 9 1 11.1% 1 +[N450I,T478R]-[R408S,T478K] FL.4.1.1 9 1 11.1% 1 +[N450I,T478R,Q613H]-[T478K] FU.4 9 9 100.0% 0 +[E180V,Y453F,T478R,T547I]-[T478K] (consensus) AQ.2 9 5 55.6% 0 +[R346S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AQ.2 9 4 44.4% 1 +[R346S,V1129L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XCB 9 3 33.3% 0 +[H69-,V70-,V213G,S247N,Y248-,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) XCB 9 3 33.3% 1 +[H69-,V70-,V213G,S247N,Y248-,A262S,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XCB 9 1 11.1% 1 +[H69-,V70-,V213G,S247N,Y248-,G257V,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XCB 9 1 11.1% 1 +[H69-,V70-,V213G,S247N,Y248-,G339D,K444T,L452R,F486V,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XCB 9 1 11.1% 2 +[H69-,V70-,V213G,S247N,Y248-,A262S,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] B.1.1.342 9 6 66.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.342 9 3 33.3% 1 +[A570V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.500 9 9 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.387 9 7 77.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.387 9 1 11.1% 1 +[F1052L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.387 9 1 11.1% 1 +[G1124D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.486 9 2 22.2% 0 +[L141F,G142-,V143-,Q183H,Q493K,S494P,I870V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.486 9 2 22.2% 4 +[L141F,G142-,V143-,E484K,S494P,I870V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.486 9 2 22.2% 10 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.486 9 1 11.1% 4 +[L141-,G142-,V143-,Q183H,F486I,S494P,I870V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.486 9 1 11.1% 9 +[S12-,S13-,Q14-,C15-,V16-,N17-,L18-,L141F,G142-,V143-,Q183H,N440D,Q493K,S494P,I870V,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.491 9 9 100.0% 0 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.147 9 8 88.9% 0 +[N185S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.147 9 1 11.1% 1 +[P26S,N185S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.182 9 7 77.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.182 9 1 11.1% 1 +[M153I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.182 9 1 11.1% 1 +[N422K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.458 9 9 100.0% 0 +[V213A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) HD.1 9 5 55.6% 0 +[R346I]-[R346T] (consensus) HD.1 9 1 11.1% 2 +[R346I]-[G142D,R346T,K417N] HD.1 9 1 11.1% 1 +[R346I]-[R346T,K417N] HD.1 9 1 11.1% 1 +[R346I,S494P]-[R346T] HD.1 9 1 11.1% 1 +[R346I,C1247F]-[R346T] CH.1.1.4 9 5 55.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P681R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,P681H] (consensus) CH.1.1.4 9 3 33.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P681R,D839N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,P681H] CH.1.1.4 9 1 11.1% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P681R,D839N,I844V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,P681H] BA.2.79.1 9 8 88.9% 0 +[V213G,Y248S,G339D,N450D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.79.1 9 1 11.1% 1 +[V213G,Y248S,G339D,N450D,Q493R,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.342 9 8 88.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.342 9 1 11.1% 3 +[I664M,I670V,S673G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KZ.1 9 8 88.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KZ.1 9 1 11.1% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] C.21 8 4 50.0% 0 +[E819D,T883A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.21 8 4 50.0% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.449 8 8 100.0% 0 +[E180G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.61 8 6 75.0% 0 +[L18F,T51I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.61 8 1 12.5% 2 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.61 8 1 12.5% 1 +[L18F,T51I,A222V,A475S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JQ.2.1 8 4 50.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JQ.2.1 8 2 25.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] JQ.2.1 8 1 12.5% 2 +[+16MPLF,R21T,S50L,H69F,V70-,S71-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JQ.2.1 8 1 12.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1027S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.12 8 5 62.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.12 8 1 12.5% 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.12 8 1 12.5% 1 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.12 8 1 12.5% 2 +[L5F,+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] B.1.1.193 8 8 100.0% 0 +[L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) BA.1.24 8 2 25.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,E340K,Q493R,G496S,T547K,I670M,N856K,G885S,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,S375F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.24 8 1 12.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,E340Q,Q493R,G496S,T547K,I670M,N856K,G885S,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,S375F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.24 8 1 12.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,E340K,S371L,Q493R,G496S,T547K,I670M,N856K,G885S,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,S375F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.24 8 1 12.5% 6 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,E340K,S371L,L452M,Q493R,G496S,T547K,I670L,N856K,D936Y,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.24 8 1 12.5% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,E340Q,Q493R,G496S,T547K,I670M,L822F,N856K,G885S,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,S375F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XBB.1.17 8 4 50.0% 0 +[F486S]-[F486P] (consensus) XBB.1.17 8 1 12.5% 1 +[D215H,F486S]-[F486P] XBB.1.17 8 1 12.5% 1 +[S255F,F486S]-[F486P] XBB.1.17 8 1 12.5% 2 +[D215H,F486S]-[Y144-,F486P] XBB.1.17 8 1 12.5% 1 +[K182I,F486S]-[F486P] C.22 8 5 62.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.22 8 2 25.0% 4 +[E484K,K558M,Q677H,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.22 8 1 12.5% 1 +[N925D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.64 8 4 50.0% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.64 8 2 25.0% 1 +[L18F,H69Y,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.64 8 2 25.0% 1 +[L18F,A222V,Q779K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.319 8 6 75.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.319 8 1 12.5% 1 +[D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.319 8 1 12.5% 1 +[G257S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.90 8 8 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.25 8 5 62.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.25 8 2 25.0% 1 +[E1188A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.25 8 1 12.5% 1 +[A903S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.614 8 7 87.5% 0 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.614 8 1 12.5% 1 +[N925K,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.17.2 8 3 37.5% 0 +[F486S]-[T19I,L24-,P25-,P26-,A27S,F486P] XBB.1.17.2 8 2 25.0% 4 +[F486S]-[T19I,F486P] (consensus) XBB.1.17.2 8 1 12.5% 7 +[M153I,F486S]-[R408S,F486P] XBB.1.17.2 8 1 12.5% 1 +[F486S]-[T19I,L24-,P25-,P26-,A27S,R346T,F486P] XBB.1.17.2 8 1 12.5% 6 +[F486S,I742V]-[F486P] BR.1.1 8 8 100.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,T307S,K444M,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) GQ.1.1 8 5 62.5% 0 +[K147E,W152R,F157L,I210V,+254P,G257-,K444T,L452R]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F490S] (consensus) GQ.1.1 8 1 12.5% 3 +[K147E,W152R,F157L,I210V,P251R,+254P,G257-,K444T,L452R,N481I]-[T19I,V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F490S] GQ.1.1 8 1 12.5% 1 +[K147E,W152R,F157L,I210V,+254P,G257-,K444T,L452R,L1200F]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F490S] GQ.1.1 8 1 12.5% 2 +[L54F,K147E,W152R,F157L,I210V,+254P,G257-,K444T,L452R,T1117I]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F490S] B.1.1.84 8 8 100.0% 0 +[A653V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) CS.1 8 4 50.0% 0 +[V3G,V6F,H69-,V70-,V213G,G339D,N354D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CS.1 8 3 37.5% 1 +[V3G,H69-,V70-,V213G,G339D,N354D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CS.1 8 1 12.5% 1 +[V3G,V6F,T29I,H69-,V70-,V213G,G339D,N354D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] KW.1.2 8 4 50.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KW.1.2 8 1 12.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529T,E554K,A570V,T572I,P621S,P681R,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KW.1.2 8 1 12.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529T,E554K,A570V,T572I,P621S,P681R,A845V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KW.1.2 8 1 12.5% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529T,E554K,A570V,T572I,P621S,P681R,V860F,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KW.1.2 8 1 12.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.9.1 8 8 100.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) BA.2.86.4 8 5 62.5% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) BA.2.86.4 8 1 12.5% 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.4 8 1 12.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,N487T,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.4 8 1 12.5% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,E1072Q,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BM.2.2 8 4 50.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.2.2 8 2 25.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,F486P,F490S] BM.2.2 8 2 25.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L455S,F490V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CW.1 8 8 100.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,F486P,F490S] (consensus) XU 7 7 100.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) B.1.1.393 7 4 57.1% 0 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.393 7 2 28.6% 1 +[E484K,A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.393 7 1 14.3% 1 +[S256L,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] LC.1 7 3 42.9% 0 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] LC.1 7 3 42.9% 5 +[+16MPLF,R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] LC.1 7 1 14.3% 1 +[R21T,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) B.1.1.422 7 7 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.405 7 7 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.47 7 5 71.4% 0 +[F486S]-[F486P] (consensus) XBB.1.47 7 2 28.6% 1 +[F486S,V1122G]-[F486P] B.1.607 7 6 85.7% 0 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.607 7 1 14.3% 1 +[D936Y,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JN.1.7.1 7 5 71.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.7.1 7 1 14.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1101Y,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.7.1 7 1 14.3% 4 +[+16MPLF,R21T,L24S,P25T,P26Q,S50L,I68T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.5.1 7 4 57.1% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.5.1 7 1 14.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.5.1 7 1 14.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.5.1 7 1 14.3% 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,A475S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.13.1 7 3 42.9% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.13.1 7 1 14.3% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.13.1 7 1 14.3% 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.13.1 7 1 14.3% 7 +[L5F,R21T,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.13.1 7 1 14.3% 5 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1.9.2 7 3 42.9% 0 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] JN.1.9.2 7 2 28.6% 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1.9.2 7 1 14.3% 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] JN.1.9.2 7 1 14.3% 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] BM.6 7 4 57.1% 0 +[G75V,K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BM.6 7 1 14.3% 2 +[G75V,K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.6 7 1 14.3% 6 +[G75V,K147E,W152R,F157L,I210V,V213G,G257S,L455S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.6 7 1 14.3% 6 +[G75V,K147E,W152R,F157L,I210V,V213G,G257S,R346I,L455S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] AM.1 6 5 83.3% 0 +[G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AM.1 6 1 16.7% 1 +[G75V,G1251V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.80 6 3 50.0% 0 +[V213G,G339D,E340Q,K356T,Q493R,Q564E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.80 6 2 33.3% 1 +[V213G,G339D,E340Q,K356T,K417T,Q493R,Q564E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.80 6 1 16.7% 3 +[V213G,G339D,E340K,K356T,Q493R,T572I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.335 6 5 83.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.335 6 1 16.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.29 6 6 100.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.414 6 5 83.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.414 6 1 16.7% 1 +[K77R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.482 6 5 83.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.482 6 1 16.7% 1 +[S151I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110.2 6 6 100.0% 0 +[P631S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.410 6 5 83.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.410 6 1 16.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.197 6 6 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.483 6 6 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.40 6 5 83.3% 0 +[Y453F,F486S]-[F486P] (consensus) XBB.1.40 6 1 16.7% 1 +[Y453F,F486S,T768N]-[F486P] B.1.434 6 2 33.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.434 6 2 33.3% 1 +[G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.434 6 1 16.7% 2 +[S50L,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.434 6 1 16.7% 3 +[T29I,S704L,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XCN 6 6 100.0% 0 +[P82H,K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T,F456L,P631S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V] (consensus) KU.1 6 6 100.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,K182Q,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) BL.2.1 6 6 100.0% 0 +[K147E,W152R,F157L,K182E,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) B.44 6 6 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.446 6 6 100.0% 0 +[I1210T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.452 5 4 80.0% 0 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.452 5 1 20.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.53 5 1 20.0% 0 +[F140I,R403K,S494P,L582F,L1224F] XBB.1.5.53 5 1 20.0% 3 +[F140I,H146K,R403K,L582F]-[H146Q] XBB.1.5.53 5 1 20.0% 3 +[F140I,R403K,L582F]-[G252V] XBB.1.5.53 5 1 20.0% 2 +[F140I,R403K,L582F] (consensus) XBB.1.5.53 5 1 20.0% 1 +[F140I,R403K,S494P,L582F] XBB.1.12.1 5 3 60.0% 0 +[Y453F,F486S,Q613H,E1202Q]-[F486P] (consensus) XBB.1.12.1 5 1 20.0% 2 +[Y453F,F486S,Q613H,E1202Q]-[V83A,F486P,Y505H] XBB.1.12.1 5 1 20.0% 1 +[H146K,Y453F,F486S,Q613H,E1202Q]-[H146Q,F486P] EG.2.1 5 3 60.0% 0 +[V327I,F456L,T478R]-[T478K] (consensus) EG.2.1 5 1 20.0% 1 +[V327I,F456L,T478R]-[K417N,T478K] EG.2.1 5 1 20.0% 2 +[V327I,F456L,T478R]-[Y144-,R408S,T478K] XBC.2.1 5 5 100.0% 0 +[P25S,K97R,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,K444T,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBB.1.5.58 5 1 20.0% 0 +[H146K,G257D,S704L]-[H146Q] XBB.1.5.58 5 1 20.0% 3 +[H146N,S704L]-[Y144-,H146Q] XBB.1.5.58 5 1 20.0% 2 +[H146K,S704L,S875A]-[H146Q] XBB.1.5.58 5 1 20.0% 7 +[L141-,G142-,V143-,H146K,T478R,P521Q,P681R,S704L]-[G142D,H146Q,T478K,P681H] XBB.1.5.58 5 1 20.0% 1 +[H146K,S704L]-[H146Q] (consensus) B.1.475 5 5 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.484 5 1 20.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.484 5 1 20.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.484 5 1 20.0% 2 +[E516Q,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.484 5 1 20.0% 1 +[G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.484 5 1 20.0% 1 +[C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FY.7 5 4 80.0% 0 +[Y200C,D228E,G769A,D1168E] (consensus) FY.7 5 1 20.0% 2 +[G769A,D1168E] B.1.1.444 5 4 80.0% 0 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.444 5 1 20.0% 1 +[T274I,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.316 5 5 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.12 5 3 60.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.12 5 1 20.0% 1 +[E1144Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.12 5 1 20.0% 2 +[L242P,D614N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.395 5 5 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.31.1 5 4 80.0% 0 +[Y453F,T478R,F486S,E554K]-[T478K,F486P] (consensus) XBB.1.31.1 5 1 20.0% 5 +[H245N,G257D,V445A,T478R,F486S,E554K]-[G252V,V445P,T478K,F486P] B.1.633 5 5 100.0% 0 +[T76I,D253N,L452R,T572N,P681R,D796H,T859N,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) JN.2.2.1 5 5 100.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,N487D,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDQ.3 5 4 80.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] (consensus) XDQ.3 5 1 20.0% 25 +[R21T,S50L,H69-,V70-,D111G,K113R,V127F,F157S,R158G,A348S,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,S596G,S939F]-[V83A,H146Q,V445P,E484A,F490S] B.1.1.91 5 4 80.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.91 5 1 20.0% 1 +[D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AH.1 4 2 50.0% 0 +[V3G,L5F,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AH.1 4 1 25.0% 1 +[V3G,L5F,S689I,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AH.1 4 1 25.0% 2 +[V3G,L5F,S530P,R765C,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.388 4 2 50.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.388 4 2 50.0% 1 +[G181V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KP.4 4 1 25.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] KP.4 4 1 25.0% 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.4 4 1 25.0% 12 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K187S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] KP.4 4 1 25.0% 6 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) None 4 2 50.0% 0 +[E180V,T478R]-[T478K] (consensus) None 4 1 25.0% 2 +[E180V,T478R,T547I,V1176F]-[T478K] None 4 1 25.0% 2 CA.4 4 4 100.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F490S] (consensus) XBB.3.5 4 2 50.0% 0 +[F486S]-[G252V,F486P] (consensus) XBB.3.5 4 1 25.0% 1 +[F486S]-[G252V,K417N,F486P] XBB.3.5 4 1 25.0% 1 +[F486S]-[H146Q,G252V,F486P] B.1.1.399 4 4 100.0% 0 +[W258L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) BA.2.87.1 4 4 100.0% 0 +[C15-,V16-,N17-,L18-,T19-,T20-,R21-,T22-,Q23-,H69-,V70-,G75D,S98F,V126A,C136-,N137-,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,H146-,W152L,R190S,V213G,D215G,G339D,K417T,K444N,V445G,L452M,N481K,P621S,V642G,N679R,S691P,T791I,D796H,D936G]-[T19I,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,T478K,F486P,F490S,N679K,D796Y] (consensus) XBB.1.48 4 4 100.0% 0 +[L455F,F456L,F486S]-[F486P] (consensus) B.1.1.427 4 3 75.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.427 4 1 25.0% 1 +[A243S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.408 4 3 75.0% 0 +[P26S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.408 4 1 25.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.36 4 3 75.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.36 4 1 25.0% 1 +[A435S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.10 4 3 75.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.10 4 1 25.0% 1 +[A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FP.2.1.2 4 4 100.0% 0 +[F186S,T478R,P521S]-[T478K] (consensus) BM.4 4 3 75.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BM.4 4 1 25.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] B.1.488 4 3 75.0% 0 +[R847T,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.488 4 1 25.0% 1 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XDQ.2 4 3 75.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,N487D,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) XDQ.2 4 1 25.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,D198G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,N487D,E554K,A570V,P621S,P681R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] XBB.1.2 4 4 100.0% 0 +[F486S,S640F]-[F486P] (consensus) M.2 3 3 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.327 3 3 100.0% 0 +[I1172V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.334 3 1 33.3% 0 +[P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.334 3 1 33.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.334 3 1 33.3% 2 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.499.1 3 3 100.0% 0 +[A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) FY.4 3 1 33.3% 0 +[Y200C,Y451H] (consensus) FY.4 3 1 33.3% 2 +[Y200C,Y451H,S494P,V1228L] FY.4 3 1 33.3% 1 +[K150N,Y200C,Y451H] EG.9 3 3 100.0% 0 +[A344V,R403K] (consensus) XBB.4.1 3 3 100.0% 0 +[L5F,K444R,T470N,F486S]-[G252V,F486P] (consensus) BS.1.2 3 3 100.0% 0 +[V213N,+213GEG,G257V,G339D,T430I,L452R,G476-,T478N,+478K,S640F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,S477N,T478K,F486P,F490S] (consensus) XDW 3 2 66.7% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,A701V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] (consensus) XDW 3 1 33.3% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,A701V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] XBB.1.23 2 2 100.0% 0 +[F486S]-[F486P] (consensus) XBC.1.1.2 2 2 100.0% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) JB.1 2 2 100.0% 0 +[F140I,N148T,R403K,L582F] (consensus) GA.4.1.1 2 1 50.0% 0 +[D215H,H245Y,E340D,K356T,T478R,E554K,Q675H,S704L]-[T478K] (consensus) GA.4.1.1 2 1 50.0% 1 +[D215H,H245Y,K356T,T478R,E554K,Q675H,S704L]-[T478K] AE.5 2 1 50.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.5 2 1 50.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.641 2 1 50.0% 0 +[T22I,H49Y,T95I,V143D,Y145-,S247G,F486L,N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.641 2 1 50.0% 4 +[H49Y,T95I,V143D,Y145-,F486L,N501T,Q613H,L1265I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.3 2 1 50.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.3 2 1 50.0% 2 +[T33I,Q52R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] KY.1 2 1 50.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) KY.1 2 1 50.0% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] XDD.1.1.1 2 2 100.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,I584V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) XBC 2 1 50.0% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,T478R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,T478K,F490S] (consensus) XBC 2 1 50.0% 2 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,N460K,F490S] A.30 2 1 50.0% 0 +[D80Y,I210-,D215G,R246M,S247-,Y248-,L249-,R346K,T478R,E484K,Q957H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,N764K,D796Y,Q954H,N969K] (consensus) A.30 2 1 50.0% 1 +[D80Y,I210-,D215G,R246M,S247-,Y248-,L249-,R346K,T478R,E484K,K811E,Q957H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,N679K,N764K,D796Y,Q954H,N969K] XT 2 2 100.0% 0 +[G75V,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) HM.1 1 1 100.0% 0 +[A348T,N481K] (consensus) B.1.285 1 1 100.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) XBB.1.49 1 1 100.0% 0 +[R346S]-[R346T] (consensus) JN.1.8.4 1 1 100.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) KZ.1.1 1 1 100.0% 0 +[+16MPLF,R21T,S50L,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) B.1.350.1 1 1 100.0% 0 +[Q677H,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus)
last modified: Sat Apr 6 07:34 2024
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Questions or comments? Contact us at seq-info@lanl.gov.
Questions or comments? Contact us at seq-info@lanl.gov.
