COVID-19 Viral Genome Analysis Pipeline
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Frequency Changes in Common Forms
Last update: Apr 23, 2025
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SPIKE sequences: Exhaustive list of Last 60 days, Global, Do not break out by lineage
Compute mutations relative to XBB.1.5 baseline sequence
As new lineages emerge, there are often many sequences with many ambiguous base calls. Our pipeline filters out such sequences, and as a consequence we undercount the number of sequences in GISAID that have been specified as members of related Pango lineages. Our strategy, however, enables us to use strictly high quality sequences to identify and track the common forms in emerging lineages.
COMMON FORMS CHANGES FOR SPIKE WITH A GIVEN PANGO LINEAGE DESIGNATION
For each lineage, we show the most common forms of SPIKE, and we show the forms that are most significantly increasing or decreasing. Also shown is the Hamming distance (HD) between each form and the most common form in that lineage. Deletions relative to the baseline reference strain are indicated with a dash (e.g. the two amino acid deletion at positions 156-157 is indicated with 'E156-,F157-'), and insertions are denoted by a plus sign (e.g. an extra T at position 143 is written '+143T'). Abs Differences in later vs early fractions, expressed as percent. Relative Differences range between -100% and +100%, using formula: rel = 100*(later-early)/max(later,early) percent, applied to the early and later fractions. The p-value associated with increase or decrease is computed by Fisher's exact test, and is meant to be used only as a rough guide to the significance of the change. Since the computation is based on assumptions (such as independent and unbiased sampling) that may not hold in practice, the p-value should not be taken too literally. The first line of each lineage section indicates counts for the full lineage relative to all the sequences. 'Lineage Count' in this first line is actually the full sequence count. 'Form Count' in this first line is actually the full lineage count, and 'Form Pct' refers to lineage count relative to full sequence set.
We show all the forms.
[Note: Mutation strings are relative to baseline XBB.1.5].
This output is based on 9265 sequences sampled from 2025-02-14 to 2025-04-15
This total interval is split into two sub-intervals.
Total: 2025-02-14 to 2025-04-15 (9265)
Early: 2025-02-14 to 2025-03-03 (4493)
Later: 2025-03-04 to 2025-04-15 (4772)
Baseline XBB.1.5: [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
Pango Lineage Form Form Counts Fractions Differences Lineage Count Count Pct Early/Later Early/Later Abs Relative pval HD [Form as mutation string] N/A 9265 1258 13.6% 792/466 0.17627/0.09765 -7.86% -44.6% <1e-10 0 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 947 10.2% 355/592 0.07901/0.12406 +4.50% +36.3% <1e-10 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 478 5.2% 244/234 0.05431/0.04904 -0.53% -9.7% 3e-1 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 310 3.3% 159/151 0.03539/0.03164 -0.37% -10.6% 3e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 295 3.2% 143/152 0.03183/0.03185 +0.00% +0.1% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 227 2.5% 115/112 0.02560/0.02347 -0.21% -8.3% 5e-1 4 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 157 1.7% 50/107 0.01113/0.02242 +1.13% +50.4% 2e-5 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 153 1.7% 65/88 0.01447/0.01844 +0.40% +21.5% 1e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 127 1.4% 66/61 0.01469/0.01278 -0.19% -13.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 107 1.2% 55/52 0.01224/0.01090 -0.13% -11.0% 6e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 102 1.1% 17/85 0.00378/0.01781 +1.40% +78.8% <1e-10 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 97 1.0% 76/21 0.01692/0.00440 -1.25% -74.0% 2e-9 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 94 1.0% 64/30 0.01424/0.00629 -0.80% -55.9% 2e-4 3 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) N/A 9265 85 0.9% 45/40 0.01002/0.00838 -0.16% -16.3% 4e-1 12 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 78 0.8% 7/71 0.00156/0.01488 +1.33% +89.5% <1e-10 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 71 0.8% 30/41 0.00668/0.00859 +0.19% +22.3% 3e-1 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 56 0.6% 14/42 0.00312/0.00880 +0.57% +64.6% 4e-4 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 52 0.6% 13/39 0.00289/0.00817 +0.53% +64.6% 7e-4 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 50 0.5% 15/35 0.00334/0.00733 +0.40% +54.5% 1e-2 7 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 47 0.5% 26/21 0.00579/0.00440 -0.14% -24.0% 4e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 37 0.4% 12/25 0.00267/0.00524 +0.26% +49.0% 7e-2 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 37 0.4% 21/16 0.00467/0.00335 -0.13% -28.3% 3e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 35 0.4% 9/26 0.00200/0.00545 +0.34% +63.2% 1e-2 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 35 0.4% 3/32 0.00067/0.00671 +0.60% +90.0% 6e-7 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 35 0.4% 23/12 0.00512/0.00251 -0.26% -50.9% 4e-2 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 35 0.4% 21/14 0.00467/0.00293 -0.17% -37.2% 2e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 34 0.4% 17/17 0.00378/0.00356 -0.02% -5.8% 9e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 33 0.4% 13/20 0.00289/0.00419 +0.13% +31.0% 4e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 33 0.4% 23/10 0.00512/0.00210 -0.30% -59.1% 2e-2 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 33 0.4% 26/7 0.00579/0.00147 -0.43% -74.7% 7e-4 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 30 0.3% 14/16 0.00312/0.00335 +0.02% +7.1% 9e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 30 0.3% 15/15 0.00334/0.00314 -0.02% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 29 0.3% 17/12 0.00378/0.00251 -0.13% -33.5% 4e-1 7 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 28 0.3% 16/12 0.00356/0.00251 -0.10% -29.4% 4e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 27 0.3% 16/11 0.00356/0.00231 -0.13% -35.3% 3e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 26 0.3% 20/6 0.00445/0.00126 -0.32% -71.8% 5e-3 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 26 0.3% 14/12 0.00312/0.00251 -0.06% -19.3% 7e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 23 0.2% 13/10 0.00289/0.00210 -0.08% -27.6% 5e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 22 0.2% 12/10 0.00267/0.00210 -0.06% -21.5% 7e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 22 0.2% 6/16 0.00134/0.00335 +0.20% +60.2% 5e-2 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 21 0.2% 0/21 0.00000/0.00440 +0.44% +100.0% 1e-6 8 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 21 0.2% 1/20 0.00022/0.00419 +0.40% +94.7% 2e-5 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 21 0.2% 9/12 0.00200/0.00251 +0.05% +20.3% 7e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 20 0.2% 9/11 0.00200/0.00231 +0.03% +13.1% 8e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,P139S,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 20 0.2% 4/16 0.00089/0.00335 +0.25% +73.4% 1e-2 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 19 0.2% 9/10 0.00200/0.00210 +0.01% +4.4% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 19 0.2% 7/12 0.00156/0.00251 +0.10% +38.0% 4e-1 11 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 19 0.2% 9/10 0.00200/0.00210 +0.01% +4.4% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 19 0.2% 13/6 0.00289/0.00126 -0.16% -56.5% 1e-1 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 19 0.2% 13/6 0.00289/0.00126 -0.16% -56.5% 1e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 19 0.2% 9/10 0.00200/0.00210 +0.01% +4.4% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 18 0.2% 10/8 0.00223/0.00168 -0.05% -24.7% 6e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 18 0.2% 1/17 0.00022/0.00356 +0.33% +93.8% 2e-4 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,M153V,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 17 0.2% 6/11 0.00134/0.00231 +0.10% +42.1% 3e-1 10 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 17 0.2% 6/11 0.00134/0.00231 +0.10% +42.1% 3e-1 14 +[N17M,+17P,T19F,T20S,R21L,+21I,Q23T,L24N,P25Q,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 17 0.2% 13/4 0.00289/0.00084 -0.21% -71.0% 3e-2 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 17 0.2% 5/12 0.00111/0.00251 +0.14% +55.7% 1e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 16 0.2% 9/7 0.00200/0.00147 -0.05% -26.8% 6e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 16 0.2% 7/9 0.00156/0.00189 +0.03% +17.4% 8e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 16 0.2% 3/13 0.00067/0.00272 +0.21% +75.5% 2e-2 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N641K,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 15 0.2% 14/1 0.00312/0.00021 -0.29% -93.3% 4e-4 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150Q,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 15 0.2% 8/7 0.00178/0.00147 -0.03% -17.6% 8e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 15 0.2% 9/6 0.00200/0.00126 -0.07% -37.2% 4e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 15 0.2% 5/10 0.00111/0.00210 +0.10% +46.9% 3e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Y266H,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 15 0.2% 8/7 0.00178/0.00147 -0.03% -17.6% 8e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 14 0.2% 1/13 0.00022/0.00272 +0.25% +91.8% 2e-3 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 14 0.2% 9/5 0.00200/0.00105 -0.10% -47.7% 3e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 14 0.2% 6/8 0.00134/0.00168 +0.03% +20.3% 8e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 14 0.2% 4/10 0.00089/0.00210 +0.12% +57.5% 2e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 14 0.2% 7/7 0.00156/0.00147 -0.01% -5.8% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 14 0.2% 12/2 0.00267/0.00042 -0.23% -84.3% 6e-3 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 13 0.1% 5/8 0.00111/0.00168 +0.06% +33.6% 6e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 13 0.1% 8/5 0.00178/0.00105 -0.07% -41.2% 4e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 13 0.1% 0/13 0.00000/0.00272 +0.27% +100.0% 3e-4 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,S155I,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 13 0.1% 5/8 0.00111/0.00168 +0.06% +33.6% 6e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500A,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 12 0.1% 0/12 0.00000/0.00251 +0.25% +100.0% 5e-4 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 12 0.1% 9/3 0.00200/0.00063 -0.14% -68.6% 8e-2 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,R214H,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 12 0.1% 10/2 0.00223/0.00042 -0.18% -81.2% 2e-2 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 12 0.1% 3/9 0.00067/0.00189 +0.12% +64.6% 1e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 12 0.1% 6/6 0.00134/0.00126 -0.01% -5.8% 1e+0 5 +[R21T,T22N,G35S,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 12 0.1% 1/11 0.00022/0.00231 +0.21% +90.3% 7e-3 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 11 0.1% 4/7 0.00089/0.00147 +0.06% +39.3% 6e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 11 0.1% 5/6 0.00111/0.00126 +0.01% +11.5% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679T,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 10 0.1% 0/10 0.00000/0.00210 +0.21% +100.0% 2e-3 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 10 0.1% 5/5 0.00111/0.00105 -0.01% -5.8% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 1/9 0.00022/0.00189 +0.17% +88.2% 2e-2 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 2/8 0.00045/0.00168 +0.12% +73.4% 1e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,H146-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 10 0.1% 0/10 0.00000/0.00210 +0.21% +100.0% 2e-3 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 3/7 0.00067/0.00147 +0.08% +54.5% 3e-1 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 10 0.1% 10/0 0.00223/0.00000 -0.22% -100.0% 7e-4 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1101Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 7/3 0.00156/0.00063 -0.09% -59.6% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 5/5 0.00111/0.00105 -0.01% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 7/3 0.00156/0.00063 -0.09% -59.6% 2e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 6/4 0.00134/0.00084 -0.05% -37.2% 5e-1 9 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 10 0.1% 5/5 0.00111/0.00105 -0.01% -5.8% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 3/7 0.00067/0.00147 +0.08% +54.5% 3e-1 10 +[+16MPLF,R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 9/1 0.00200/0.00021 -0.18% -89.5% 1e-2 1 +[+16MPLF,R21T,T22N,H49Y,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 10/0 0.00223/0.00000 -0.22% -100.0% 7e-4 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 10 0.1% 6/4 0.00134/0.00084 -0.05% -37.2% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 9 0.1% 6/3 0.00134/0.00063 -0.07% -52.9% 3e-1 1 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 9 0.1% 7/2 0.00156/0.00042 -0.11% -73.1% 1e-1 8 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 9 0.1% 6/3 0.00134/0.00063 -0.07% -52.9% 3e-1 12 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 9 0.1% 1/8 0.00022/0.00168 +0.15% +86.7% 4e-2 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,G946V,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 9 0.1% 2/7 0.00045/0.00147 +0.10% +69.7% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 9 0.1% 3/6 0.00067/0.00126 +0.06% +46.9% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 9 0.1% 4/5 0.00089/0.00105 +0.02% +15.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 9 0.1% 0/9 0.00000/0.00189 +0.19% +100.0% 4e-3 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 9 0.1% 5/4 0.00111/0.00084 -0.03% -24.7% 7e-1 14 +[L5F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445Q,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 8 0.1% 8/0 0.00178/0.00000 -0.18% -100.0% 3e-3 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,S680Y,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 8 0.1% 5/3 0.00111/0.00063 -0.05% -43.5% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,V1133I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 8 0.1% 8/0 0.00178/0.00000 -0.18% -100.0% 3e-3 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 8 0.1% 7/1 0.00156/0.00021 -0.13% -86.5% 3e-2 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 8 0.1% 7/1 0.00156/0.00021 -0.13% -86.5% 3e-2 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 8 0.1% 4/4 0.00089/0.00084 -0.01% -5.8% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S704L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 1/6 0.00022/0.00126 +0.10% +82.3% 1e-1 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 7 0.1% 2/5 0.00045/0.00105 +0.06% +57.5% 5e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 7 0.1% 1/6 0.00022/0.00126 +0.10% +82.3% 1e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 7 0.1% 0/7 0.00000/0.00147 +0.15% +100.0% 2e-2 15 +[R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 7 0.1% 1/6 0.00022/0.00126 +0.10% +82.3% 1e-1 14 +[L5F,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 7 0.1% 0/7 0.00000/0.00147 +0.15% +100.0% 2e-2 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 4/3 0.00089/0.00063 -0.03% -29.4% 7e-1 5 +[R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 4/3 0.00089/0.00063 -0.03% -29.4% 7e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 6/1 0.00134/0.00021 -0.11% -84.3% 6e-2 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 6/1 0.00134/0.00021 -0.11% -84.3% 6e-2 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 4/3 0.00089/0.00063 -0.03% -29.4% 7e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 1/6 0.00022/0.00126 +0.10% +82.3% 1e-1 10 +[+16MPLF,R21T,S31-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 7 0.1% 3/4 0.00067/0.00084 +0.02% +20.3% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 4/3 0.00089/0.00063 -0.03% -29.4% 7e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 4/3 0.00089/0.00063 -0.03% -29.4% 7e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,T345S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 2/5 0.00045/0.00105 +0.06% +57.5% 5e-1 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 1/6 0.00022/0.00126 +0.10% +82.3% 1e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 7 0.1% 0/7 0.00000/0.00147 +0.15% +100.0% 2e-2 13 +[+16MPLF,R21T,S31-,S50L,A67V,H69-,V70-,V127F,H146-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 7 0.1% 1/6 0.00022/0.00126 +0.10% +82.3% 1e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 7 0.1% 5/2 0.00111/0.00042 -0.07% -62.3% 3e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 1/5 0.00022/0.00105 +0.08% +78.8% 2e-1 11 +[R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 6 0.1% 2/4 0.00045/0.00084 +0.04% +46.9% 7e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683W,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 6/0 0.00134/0.00000 -0.13% -100.0% 1e-2 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 3/3 0.00067/0.00063 -0.00% -5.8% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 5/1 0.00111/0.00021 -0.09% -81.2% 1e-1 7 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 6 0.1% 1/5 0.00022/0.00105 +0.08% +78.8% 2e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1153A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 6 0.1% 2/4 0.00045/0.00084 +0.04% +46.9% 7e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 6 0.1% 4/2 0.00089/0.00042 -0.05% -52.9% 4e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 6 0.1% 2/4 0.00045/0.00084 +0.04% +46.9% 7e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 6 0.1% 1/5 0.00022/0.00105 +0.08% +78.8% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N185D,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 6 0.1% 3/3 0.00067/0.00063 -0.00% -5.8% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,E554K,A570V,P621S,T676N,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 6 0.1% 6/0 0.00134/0.00000 -0.13% -100.0% 1e-2 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 4/2 0.00089/0.00042 -0.05% -52.9% 4e-1 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 5/1 0.00111/0.00021 -0.09% -81.2% 1e-1 9 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 6 0.1% 4/2 0.00089/0.00042 -0.05% -52.9% 4e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 6 0.1% 3/3 0.00067/0.00063 -0.00% -5.8% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 3/3 0.00067/0.00063 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 5/1 0.00111/0.00021 -0.09% -81.2% 1e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 3/3 0.00067/0.00063 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1083Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 6/0 0.00134/0.00000 -0.13% -100.0% 1e-2 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 3/3 0.00067/0.00063 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 6 0.1% 2/4 0.00045/0.00084 +0.04% +46.9% 7e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T286I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 3/3 0.00067/0.00063 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 0/6 0.00000/0.00126 +0.13% +100.0% 3e-2 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 6 0.1% 0/6 0.00000/0.00126 +0.13% +100.0% 3e-2 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 3/3 0.00067/0.00063 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,N1125K,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 6 0.1% 0/6 0.00000/0.00126 +0.13% +100.0% 3e-2 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 6 0.1% 2/4 0.00045/0.00084 +0.04% +46.9% 7e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 6 0.1% 3/3 0.00067/0.00063 -0.00% -5.8% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,R214H,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 5 0.1% 1/4 0.00022/0.00084 +0.06% +73.4% 4e-1 13 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 5 0.1% 5/0 0.00111/0.00000 -0.11% -100.0% 3e-2 2 +[F2L,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,R214H,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 0/5 0.00000/0.00105 +0.10% +100.0% 6e-2 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 5 0.1% 2/3 0.00045/0.00063 +0.02% +29.2% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 0/5 0.00000/0.00105 +0.10% +100.0% 6e-2 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 5 0.1% 3/2 0.00067/0.00042 -0.02% -37.2% 7e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 0/5 0.00000/0.00105 +0.10% +100.0% 6e-2 4 +[+16MPLF,R21T,T22N,A27-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1208H]-[P25-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 5/0 0.00111/0.00000 -0.11% -100.0% 3e-2 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 5 0.1% 3/2 0.00067/0.00042 -0.02% -37.2% 7e-1 6 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 5/0 0.00111/0.00000 -0.11% -100.0% 3e-2 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158E,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 5 0.1% 2/3 0.00045/0.00063 +0.02% +29.2% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,W152R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 4/1 0.00089/0.00021 -0.07% -76.5% 2e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 9265 5 0.1% 3/2 0.00067/0.00042 -0.02% -37.2% 7e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 1/4 0.00022/0.00084 +0.06% +73.4% 4e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 5 0.1% 2/3 0.00045/0.00063 +0.02% +29.2% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,N1187T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 5/0 0.00111/0.00000 -0.11% -100.0% 3e-2 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,F1103L,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 2/3 0.00045/0.00063 +0.02% +29.2% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 5 0.1% 4/1 0.00089/0.00021 -0.07% -76.5% 2e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 1/4 0.00022/0.00084 +0.06% +73.4% 4e-1 6 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 4/1 0.00089/0.00021 -0.07% -76.5% 2e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 3/2 0.00067/0.00042 -0.02% -37.2% 7e-1 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 4/1 0.00089/0.00021 -0.07% -76.5% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 1/4 0.00022/0.00084 +0.06% +73.4% 4e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 1/4 0.00022/0.00084 +0.06% +73.4% 4e-1 9 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 3/2 0.00067/0.00042 -0.02% -37.2% 7e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 1/4 0.00022/0.00084 +0.06% +73.4% 4e-1 5 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 5/0 0.00111/0.00000 -0.11% -100.0% 3e-2 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 5 0.1% 5/0 0.00111/0.00000 -0.11% -100.0% 3e-2 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481R,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1073N,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 4/0 0.00089/0.00000 -0.09% -100.0% 6e-2 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 4/0 0.00089/0.00000 -0.09% -100.0% 6e-2 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,P521S,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 4/0 0.00089/0.00000 -0.09% -100.0% 6e-2 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 2/2 0.00045/0.00042 -0.00% -5.8% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N658D,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 4 0.0% 2/2 0.00045/0.00042 -0.00% -5.8% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 4 0.0% 2/2 0.00045/0.00042 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 2/2 0.00045/0.00042 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,P272S,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,D936Y,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,P384S,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 2 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 2/2 0.00045/0.00042 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S31F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262D,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 2/2 0.00045/0.00042 -0.00% -5.8% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 4/0 0.00089/0.00000 -0.09% -100.0% 6e-2 10 +[R21T,S31-,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680Y,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K147E,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 4 0.0% 4/0 0.00089/0.00000 -0.09% -100.0% 6e-2 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,R78K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q239R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 2/2 0.00045/0.00042 -0.00% -5.8% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 4/0 0.00089/0.00000 -0.09% -100.0% 6e-2 9 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,Q173H,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,N679K,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 1 +[+16MPLF,R21T,T22N,F32L,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 2/2 0.00045/0.00042 -0.00% -5.8% 1e+0 6 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 7 +[+16MPLF,R21T,S31-,S50L,W64C,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 40 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] N/A 9265 4 0.0% 4/0 0.00089/0.00000 -0.09% -100.0% 6e-2 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,K558N,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 10 +[L5F,+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q675H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 1/3 0.00022/0.00063 +0.04% +64.6% 6e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,R78S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 4/0 0.00089/0.00000 -0.09% -100.0% 6e-2 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N185D,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 4 0.0% 3/1 0.00067/0.00021 -0.05% -68.6% 4e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 4 0.0% 4/0 0.00089/0.00000 -0.09% -100.0% 6e-2 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,Q779K,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 14 +[R21T,S31-,S50L,H69-,V70-,T95I,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 4 0.0% 0/4 0.00000/0.00084 +0.08% +100.0% 1e-1 10 +[R21T,S31-,S50L,Q52H,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 15 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I818V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S884A,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N185D,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,Q957L,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 3 +[+16MPLF,R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1153A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,R237S,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 15 +[N17M,+17P,T19F,T20N,R21F,+21I,Q23T,L24N,P25Q,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 2 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S813N,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,A243S,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Y1155F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 5 +[R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D950N,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,N61D,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,Q134K,K150N,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V83F,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1094I,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,I68F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 9 +[R21T,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T874I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1058Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 5 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441V,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,D796H,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,D796H,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H,D796Y] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A899S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 2 +[+16MPLF,R21T,T22N,T29I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 6 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,P139S,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,R765H,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,N1023S,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 11 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1101Y,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,D111N,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N185I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 1/2 0.00022/0.00042 +0.02% +46.9% 1e+0 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,N148T,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,K558N,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 2/1 0.00045/0.00021 -0.02% -52.9% 6e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478R,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 3/0 0.00067/0.00000 -0.07% -100.0% 1e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,L585F,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N641K,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 3 0.0% 0/3 0.00000/0.00063 +0.06% +100.0% 3e-1 7 +[F4S,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1263R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1263R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679M,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477K,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,T430I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,D138Y,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K150N,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MSLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264Y,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V83F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A899S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,P251S,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212-,+213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1263Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,A123S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,D253A,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 2 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,M731I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Y1155F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,K147E,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,N137K,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,A688T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,T259I,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 17 +[L18F,+18I,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,G75V,V127F,F157S,R158G,N185D,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,W152R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S98F,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q239R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E281Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16IPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,A67S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445Q,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 12 +[+16MPLF,R21T,S31-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,P809S,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N658D,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K147E,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 14 +[R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,D178N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[+16MPLF,R21T,T22N,N30I,S31-,F32-,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 4 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,G1219V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,D389G,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 3 +[+16IPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,T22N,N30I,S31-,F32-,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,K529T,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MPLF,R21T,T22N,S31F,S50L,H69P,V70-,S71-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,E654Q,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,M177I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R683L,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,A222S,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,+344S,R346-,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,R34C,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,Q690P,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,D80G,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H66R,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[L5F,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K147T,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MSLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 11 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,M153I,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P807S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16IPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[R21T,T22N,S50L,F59S,A67S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,V143F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677K,P681R,S939F,V1104L,P1143L,C1235F,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,S112P,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,Q690P,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,L179F,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K147I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 3 +[P9L,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680Y,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K150E,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,H146-,F157S,R158G,G184V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493V,E554K,A570V,P621S,P681R,T768I,S939F,V1104L,P1143L]-[Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,I68T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,D111N,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,V534I,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,P384S,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D839E,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,E1195Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,E1150K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680Y,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,T430I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,P217S,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,R78M,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G261S,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,Y145D,H146-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 6 +[+16MPLF,R21T,N30I,S31-,F32-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,N960D,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,N99D,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,G446I,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Y266H,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,N81Y,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,P1263Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K529R,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,P1162Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K529E,N532K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T573I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,A783S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,P272L,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1169V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,Q690P,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 8 +[+16MPLF,R21T,T22N,S50L,S60P,H69-,V70-,V127F,F157S,R158G,L176F,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 8 +[R21T,S31-,S50L,H69-,V70-,S98F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677L,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,G1251A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,A1070V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G75R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,E1092K,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,V551F,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 6 +[V16F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T827I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,G946R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1083Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,T259I,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[F4L,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,F186L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V407I,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1058Y,K1086R,V1104L,V1133I,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I934V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500A,E554K,A570V,P621S,P681R,A701P,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,E1195Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T883S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 8 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621F,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N532Y,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N185D,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V642G,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,A27-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1101Y,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,P139S,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 6 +[V16F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[P9T,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679T,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85Q,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G75D,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L,D1165A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K147N,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 2/0 0.00045/0.00000 -0.04% -100.0% 2e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Q271K,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 1/1 0.00022/0.00021 -0.00% -5.8% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N439K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F490Y,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I794T,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,D111N,V127F,F157S,R158G,N185D,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 11 +[R21T,S31-,S50L,H69-,V70-,V127F,S151I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P793S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,R102K,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 2 0.0% 0/2 0.00000/0.00042 +0.04% +100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,A879S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1094I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,L513F,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,L54F,H69-,V70-,V127F,E154G,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 64 +[R78S,L84I,E132Q,K147N,G181A,F338L,T385I,N440R,Y453F,R466K,F490Y,E583D,Q677H,P809S,K811R,A879S,T941S,D1257-]-[N440K,G446S,F490S,N764K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21-,+22I,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,W152R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,E654A,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,T33I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[N17M,+17P,T19F,T20N,R21F,+21I,Q23T,L24N,P25Q,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,M177I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683W,I931V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A771S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,P139T,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P793Q,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,F515V,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,L24S,P25T,P26Q,S31-,S50L,H69-,V70-,G75V,V127F,F157S,R158G,N185D,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[R21T,T22N,L24S,P25N,P26Q,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,L24S,P25N,P26Q,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I794T,S939F,V1104L,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,A243N,L244-,H245-,S256L,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,Q677E,P681R,S939F,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,Q474H,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[F2L,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,S940F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H66L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,I670M,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59A,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,S1252Y,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,L727I,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,L1203F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,K1149R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,S31-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,S60F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,L141F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K529E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486S,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679T,P681R,S939F,V1104L,P1143L,D1146H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,R78K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,A93S,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MP,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,A93S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483R,E484-,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150N,F157S,R158G,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A871V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A871V,S939F,V1104L,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,W886L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,I68T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150N,F157S,R158G,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[S13T,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T998A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1058Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,P217T,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,I1172V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,N856S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[R21T,T22N,S31-,S50L,H69-,V70-,T95I,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 18 +[R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500-,+501Y,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N501Y,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679Q,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,N856S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1191T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,G594S,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,T236S,H245N,T250N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,A243V,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,H49Y,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211I,+211G,V213-,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,E324G,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A344T,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T124I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T676A,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,P209L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,A647S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 81 +[P9L,R21T,P26L,A67V,H69-,V70-,T95I,I101T,C136-,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,H146-,K147-,N149-,F157S,N164K,S172F,K187T,N211-,L212I,+214AS,+215TD,A243-,L244-,P251S,I326V,G339Y,A348P,R403K,A435S,N440R,V445A,G446D,L452W,T478N,E484K,G496S,K529N,E554D,E583D,H625R,N641K,V642G,E654K,N679R,P681R,A688D,S704L,K795T,A852K,S939F,P1162R,D1184E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,N440K,V445P,G446S,T478K,E484A,F486P,F490S,Y505H,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1146G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85Q,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K150N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q218L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q173E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,S1252Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1066N,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683W,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,I624F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T274N,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,K558R,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I105V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,R78K,V127F,F157S,R158G,Q173H,N211-,L212I,V213G,L216F,Q239R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,G75R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S46L,S50L,H69-,V70-,R78K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 16 +[N17M,+17P,+18FNFI,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,Q677K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,T29I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,L141F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,S155I,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143F,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,M153I,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452R,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P807S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S98F,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,Q580H,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,P272S,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,M177I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,A67V,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,T250A,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,G639S,P681R,G842D,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,P174S,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[N17M,+17P,T19F,T20N,R21L,T22I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,E224Q,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,W258R,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,G482-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,V1177L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445R,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[V16F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S112A,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,I1115V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A684T,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,P139S,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1146H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,+344S,R346-,K356T,P384S,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,N679T,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,Q949H,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[L5F,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S640F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,Q493E,E554K,A570V,P621S,P681R,S939F,H1101Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,F65L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478R,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,L242F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,S477N,T478K,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,D138H,F157S,R158G,N211-,L212I,V213G,L216F,R237M,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,S71F,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,T547I,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216R,+216GSF,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1094I,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216R,+216GSF,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158E,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,D138G,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,S31-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,A688V,P809S,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,S71F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,L223I,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,R237K,H245N,S247N,A264D,I332V,K356T,V367I,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Y145L,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1073N,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,T961M,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,N30Y,S31-,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E281Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1250Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S50L,F59S,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S704L,S939F,H1101Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1249P]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,Y505H,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1018V,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254P,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147I,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,E654V,N679R,P681R,D808N,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,S151T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,K795N,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A684V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,S940F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S810L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1101Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,P139S,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[S13-,Q14-,C15-,V16-,N17-,L18-,R21-,T22-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I805M,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D936Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,G72W,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Y266H,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,A688V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21I,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MSLF,R21T,S31-,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,R765H,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,T478I,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,F192L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D796H,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H,D796Y] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T723I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677L,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,V687L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,N81S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I818M,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D745A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,W64R,H69-,V70-,A123V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K150I,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,K182T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,P384H,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,K150N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,K147I,F157S,R158G,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T961M,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q675K,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547I,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,D808N,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 42 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[T19L,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,L1244I,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[N17D,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,D568N,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,Q804H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,T19V,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[F2L,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,V705I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S50L,H69-,V70-,R78S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,Q239R,H245N,A264D,I332V,P337S,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,N606D,P621S,P681R,S939F,H1083Y,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S50L,S60P,H69-,V70-,V127F,F157S,R158G,L176F,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L,D1257-]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,I233V,H245N,A264D,I332V,K356T,N360H,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,H519Q,E554K,A570V,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,T638I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N188S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,F486L,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152S,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Y144N,Y145-,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,+126F,I128-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,Q954H,N969K] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,E96A,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A890S,S939F,V1104L,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,K113T,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,A243D,L244-,H245-,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,L754F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,S1021F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,F32-,S50L,H69-,V70-,V127F,F157S,R158G,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,N30S,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1236F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1045N,G1099S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,Q779R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,V622I,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,D1084E,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[Q14H,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,+355T,R357-,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1146G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S704L,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N657D,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,N74T,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P812L,S939F,K1086R,V1104L,E1111Q,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N460R,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A348S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[L18F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,G446-,G447-,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21-,S50L,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335S,K356T,R403K,V445H,N450D,L452W,T478R,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,R683W,I788L,S939F,P1143L,E1150D]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,D215G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,F643-,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V193L,N211-,L212I,V213G,L216F,H245N,L249F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D936H,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L179F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,A1078S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,E406Q,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,S1239N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A520S,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[P9S,N17M,+17P,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,T678I,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,N148D,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262T,A264D,F318L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,E96A,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D745G,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H,N764K] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,T19L,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,T732I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T286I,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69P,V70-,S71-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H,N764K] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T573I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,A1174V,K1205N]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31L,F32-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K535R,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,Y144N,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I844V,S939F,V1104L,V1133F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376V,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,I584V,P621S,P681R,S939F,V1104L,P1143L,D1146Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,L1024I,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R683Q,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,Q804P,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1088Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483K,E484S,G485P,F486-,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701T,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1228I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,T859-,V860-,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A344T,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,I68F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A411S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,V267L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S477N,T478K,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,F306L,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,P812S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,R765H,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[L5F,+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[Q14H,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346A,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,P39L,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R355S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,S71F,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T883I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157P,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V987F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,P793S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V382L,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376V,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1006I,V1104L,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,P39H,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,P209S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157L,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Q134R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S746A,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,N30I,S31-,F32-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,T22N,N30I,S31-,F32-,S50L,H69-,V70-,V127F,N148S,F157S,R158G,P174S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,R102K,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,F32-,S50L,H69-,V70-,V127F,W152R,F157S,R158G,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S71F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500-,+501Y,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N501Y,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,D178Y,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,M153V,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477K,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,Q677K,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,N149-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218L,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,D1163V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,Q52H,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,W64R,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,T274I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T676I,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,K529T,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,E96G,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258R,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,G482-,E484K,Q493E,E554K,A570V,P621S,P681R,A879S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486H,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,D228E,H245N,S254F,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,Q1201H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,G268S,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,V227L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S937L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,T883I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,T1027I,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[C15F,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,G482-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,L118F,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482S,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A899S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,L822F,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,L1234F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A783V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,E1195D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S46L,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1169L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K150T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1073M,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,D80Y,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1058Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,D228Y,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K529E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,H49Y,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,V1128I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,D111N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,E281Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,E154K,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1169V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679Q,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S98Y,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,Q1011L,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,A845V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N282S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500A,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q675H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,V1104L,P1143L,D1146G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,T1117A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,N30I,S31-,F32-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,V1133I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,G184D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S937T,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,W64C,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,K1245R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,D111N,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,K97N,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,A647S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,L1244F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,D111N,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,N960S,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,D80Y,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339R,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S813N,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,L335S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,S155I,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1124V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T274I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Y269H,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,T345S,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 56 +[P9-,L10-,V11-,S12-,S13-,T20-,F59S,A67V,H69-,V70-,K97T,C136F,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,R190K,N211-,L212I,G339V,L452R,F486V,A1020S]-[T19I,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[V16F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,H1083Q,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1088R,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,G1099D,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69S,S71-,G72-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,N532S,E554K,A570V,P621S,P681R,S939F,S940F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1162L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,T572I,P621S,Q675K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,P85L,V127F,F157S,R158G,N185D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,S975N,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,+203F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,E465D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,H207Y,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MSLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,D178N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1176F,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,R1014K,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[V16F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147Q,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221T,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L179I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190K,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,L822F,S939F,V1104L,P1143L,D1163G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,Y145P,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1250F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,N99S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,G35V,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445L,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,G639V,V642G,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,L118F,V127F,K147I,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,M177I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S459F,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,S151I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,V785I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85L,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1060I,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16IPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,G268S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621-,V622-,T630I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K147R,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,I788V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A846V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16IPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147E,F157S,R158G,N211-,L212-,+213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,Q954R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[S12C,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483R,E484-,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,R1185H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,D138G,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,V1104L,P1143L,I1216T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,D1084-,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,G219D,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1101R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,M740T,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,K529R,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,G838S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,K77N,V127F,D138V,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,N1187T,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,K529R,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G75V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,D1084E,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,L179F,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,I624F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S50L,F59-,+60F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,N1178K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 19 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 26 +[S31-,S50L,H69-,V70-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 24 +[S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 27 +[S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 38 +[S50L,F59S,H69-,V70-,N211-,L212I,V213G,L216F,H245N,A264D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,N440K,V445P,G446S,N460K,E484A,F490S,N679K,P681H,Q954H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 21 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262D,A264D,I332V,K356T,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 23 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H,Q954H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 25 +[H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H,Q954H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 32 +[S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 20 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 29 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,T124I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1083Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,G1267E]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,E661D,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,I598V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,N282S,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,P57S,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1129I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500A,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500A,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,E180A,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,H1101Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148S,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16IPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478R,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,R765L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1250F,D1260V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N658D,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G75V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,V62I,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,K795R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N394S,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T274I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,I670M,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D808E,S939F,P1143L,D1153A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,E154G,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,L179R,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264E,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,A67V,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,A93S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,A123S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,Q1005H,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150E,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[R21T,T22N,T29I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,A1087S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,V534I,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,M1237T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I934V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,F106L,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,I934V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,G261D,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,N764K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,T51I,H69-,V70-,V127F,F157S,R158G,N185D,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441V,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,H625R,N679R,P681R,D936Y,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MSLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,F106L,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,T572I,P621S,P681R,I934V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,E484A,F490S,P681H,N764K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,E780Q,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,S151I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,M177I,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,H1083Y,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,G1246C]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N185D,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,R78S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148S,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H,N764K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,N764K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H,N764K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,G252S,A264D,F306L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,G946V,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A263S,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 23 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N370K,R403K,E554K,A570V,P621S,P681R,A688G,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,A879S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,P272S,I332V,K356T,R403K,N440R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S31-,S50L,W64G,H69-,V70-,D80G,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 23 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1094I,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 17 +[S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S640F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 18 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N501Y,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 19 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S31P,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 17 +[V127F,F157S,R158G,F175L,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452R,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,L244-,H245Y,A264D,P272S,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,M731I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,P209T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,G72R,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,S940F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D936Y,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,T345S,R346I,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481Q,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 17 +[+16CRVMPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MSLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,V1122M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1240F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939V,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[V3I,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522V,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1162Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,R567K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1163N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,N603I,P621S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211I,+211G,V213-,R214-,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L189F,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,W436R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K150E,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,D228Y,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,R765H,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,F32S,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621A,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,N532K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Q321K,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,P561S,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,A575S,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211K,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,G181R,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,K77R,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T95I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,K356T,R403K,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,T638I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,W152R,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,S939F,K1086R,V1104L,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,G446I,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1009I,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,D1163Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,F464L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T732I,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D80Y,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31-,S50L,W64G,H69-,V70-,D80G,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,V510I,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,V736I,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765S,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T778I,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,G1171D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,T676A,S680Y,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,S31-,S50L,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1068I,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,M1233T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 32 +[H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,G446D,N450D,L452R,S477D,G504D,E554K,A570V,P621S,P681R,V772A,A899S,L938I,K964E,V1104L,P1143L,Q1201K,L1203F,I1210V,T1231I,L1265F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,N460K,S477N,F486P,F490S,P681H,D796Y] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,K278R,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,I128T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1094I,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S112L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H66Y,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1169V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F58L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,H1101Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I770V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K529E,E554K,A570V,P621S,P681R,T791I,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 71 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 43 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 58 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 58 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPK,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[L5F,+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,H1159Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,S940F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,T22N,S31P,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1129L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[L7F,+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V159I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,R408N,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,N74Y,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,T76I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q173E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,G482D,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148D,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481R,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S689N,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S689N,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,E661D,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078V,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1101Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,R237S,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T716I,S939F,V1104L,P1143L,G1251A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,H49Y,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S375-,T376-,F377-,R403K,V445H,N450D,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,S975N,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A871S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,R403K,V445H,N450D,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N641I,V642-,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,M177I,Q183H,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,R78K,V127F,F157S,R158G,N211-,L212I,V213G,L216F,Q239R,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A879V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S704L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,D796H,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H,D796Y] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,P1162A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D839Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S704L,I909V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,A27-,S31-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,P809S,S939F,K1086R,V1104L,P1143L,A1174V]-[P25-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,L754W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L,C1235S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A344V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 21 +[+16TPLF,R21T,T33A,S50L,L56I,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243N,L244I,H245-,R246-,A264D,I332V,K356T,T385I,R403K,N450D,L452W,L455S,T478I,N481R,V483-,E484K,F486H,E554K,A570V,P621S,V622-,P681R,S939F,Q1113K,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V642A,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,N440K,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,G219V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V622F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148Y,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216S,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,A163V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,N679R,P681R,S939F,K1086R,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S373P,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K529E,N532K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,F800G,S939F,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,G142H,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K529T,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1232F,K1245N,G1246F,C1250S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I326V,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,R634H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,A163S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,S31-,S50L,A67V,H69-,V70-,V127F,H146-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,M1237I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,R102I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222T,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,S940F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,S940F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[L10I,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,D950N,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,N30Y,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G181R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,A626S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,S155I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S254F,S255F,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,H146-,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,V143D,Y145-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Y674F,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[N17M,+17P,T19F,T20N,R21L,T22I,Q23I,L24T,P25N,P26Q,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,A701V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,E96G,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Y145N,H146-,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,E748Q,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939V,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,I569V,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,I844V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,V62F,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S637F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,A575S,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486S,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S112L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S373P,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S640F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264M]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[+19I,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,F1103L,V1104L,P1143L,C1248Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,N30Y,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,N30K,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,E554K,A570V,P621S,I670M,Q677H,P681R,I934V,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,V289I,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,H49Y,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T732I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,W64R,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,T716I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482A,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K986N,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,P85S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,Q613H,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,Q173R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,D138Y,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,Q493E,E554K,A570V,P621S,V622-,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,N1098S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,I105V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,E748Q,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A684T,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[V6F,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,E1202K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,M177I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157L,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,E1258D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q675K,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 20 +[R21T,S31-,S50L,H69-,V70-,V127F,P139Q,F140-,L141-,G142-,V143-,Y145-,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,V445H,N450D,L452W,F456L,N481K,V483-,E484K,Y508H,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1179T]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,S50L,H69-,V70-,T95I,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455A,N481K,V483-,E484K,T549I,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I692F,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,L176F,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L176F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,T345S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,D936H,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1101Y,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,Q613E,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,S31-,S50L,W64C,H69-,V70-,V127F,V143D,Y145-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,G946V,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,T791I,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[L8F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 17 +[L18F,+18I,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1187S]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,D1184N]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,Q613H,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 49 +[V16D,N17-,H69-,V70-,C136F,H146K,G261C,V367F,P681R,R683W,A852V]-[H146Q,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,S1170F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,T739A,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S71F,V127F,F157S,R158G,L176F,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,Q1071H,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,H49Y,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S704L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S810A,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[F2L,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S704L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 17 +[N17M,+17P,+18FNFI,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1228L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,D936Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,P809S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,+482K,E484P,G485-,F486-,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K147I,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,G72R,V127F,S151I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,L699I,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,S591A,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482S,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,E654K,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H,N764K] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,G842S,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,A845V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,A1020S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273M,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,D936Y,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,N148I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,N679R,P681R,D936Y,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K150N,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H,N764K] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H,N764K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,D950E,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,V267L,I332V,L335S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,W152R,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,A1020S,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,I1232V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222T,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,S31-,R34L,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1079S,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,M177I,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,N532K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K147I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,Q1005H,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N185I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,R765G,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N164T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G181A,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,M1237T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,A27-,S50L,F59S,H69-,V70-,V126F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 48 +[H69-,V70-,T76A,V213G,H245N,A264D,G339D,R357K,S375-,T376-,F377-,T385I,K417T,G446D,N450D,L452R,S477D,G504D,E554K,A570V,P621S,T732I,A899S,L938I,K964E,I1169F]-[H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S375F,T376A,K417N,V445P,G446S,N460K,S477N,F486P,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,M153V,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S637F,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,M153V,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683W,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,I1198M]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452R,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,S31-,S50L,H69-,V70-,V127F,K147R,F157S,R158G,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,V534I,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,A288V,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,A372V,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 17 +[R21T,S31-,S50L,H69-,V70-,V127F,K150R,F157S,R158G,N185D,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1260Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[P9L,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[L5F,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,V267L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,P521L,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K529E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N185D,F186L,R190S,V213G,L216F,H245N,P251L,A263V,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,T259I,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N641I,V642-,F643-,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,K150E,F157S,R158G,L176F,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,K529N,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680Y,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,A27-,S31-,S50L,H69-,V70-,V127F,K150R,F157S,R158G,N185D,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A879S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,D405N,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A879S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 22 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,T478R,N481K,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 22 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 20 +[S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N658D,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,T572I,T618A,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,P330S,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,L226V,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,Q1071R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481R,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[L5F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 16 +[L5F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S640Y,N641-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,F220S,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V83I,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,D111N,V127F,F157S,R158G,M177I,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1130M,P1143L,K1149Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,I1130M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,N532K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,A67S,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,Q926L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S50L,F59S,H69-,V70-,N122Y,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A1026S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,A766S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S151I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[V16F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S813G,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,C1248Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,V62F,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,G594S,V620A,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16M,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1101Y,P1143L,N1187S,S1249F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,P809S,S939F,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,M153I,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1101Y,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482S,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V976A,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1094I,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,D843N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,K182-,Q183-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547I,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,R34P,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V433I,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679T,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1088R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1083Y,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S50L,F58L,F59S,H69-,V70-,V127F,K147I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452R,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,L118F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[V16F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,D950H,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,K529R,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A694V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157L,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,V1104L,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1083Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G72W,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,T547K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,D80Y,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,E191D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679T,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P807S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,G1246S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,F186S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,H655F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,H655Y,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,K790R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21-,+22I,S31-,S50L,H69-,V70-,P85Q,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,Q954Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,Q954H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237S,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V83F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,G594S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21I,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D796H,A845S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,Q613E,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,V1104L,P1143L,R1185H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16KPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,T345S,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,P499L,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,S112L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[N17M,+17P,T19F,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A899S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,A1078S,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A344V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A783V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,K150N,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,T1006I,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,G1219C]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,N30I,S31-,F32-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446I,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,N1134D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,P174S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,L1234I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,F32-,S50L,H69-,V70-,V127F,F157S,R158G,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,W152G,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1101Y,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,S1239G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,I1114V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,G339Y,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,M153I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,P1162S,K1205N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,R78S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1083Y,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 7 +[S50L,F59S,H69-,V70-,T114S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,K278Q,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,V622A,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,N801D,S939F,P1143L,I1183F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,A292T,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,A520S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,V289L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,L841F,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,Q1201H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,T33I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[R21T,S31-,S50L,H69-,V70-,V127F,K150R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,I472V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,Q580H,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S689N,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,F59S,H69-,V70-,A123S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,N87S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1087S,V1104L,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,K77R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A260G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,H1083Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A942S,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T859I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Q271K,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K150N,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 17 +[N17M,+17P,T19F,T20N,R21P,T22L,Q23F,L24I,P25T,P26T,A27N,+27QS,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,D428G,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,G946E,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G261D,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356M,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,A123T,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,A668V,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[V6F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,A688V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,A292T,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1168G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,A1174T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182T,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,N148T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85R,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,N148T,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N657S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21K,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1247Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,G769V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,T572I,P621S,N641K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,M153I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1153A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S366A,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,A890T,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,V1104L,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,K529N,E554K,A570V,T604I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S689N,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,G261C,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,R237M,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,Y396F,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D936H,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,E340Q,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,I1172V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G1124V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,P272L,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486H,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,V127F,F157S,R158G,M177I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148D,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,N149D,M153I,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R683Q,P807S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A899S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31F,S50L,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V367I,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,G219C,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,D138H,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,G446T,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T961M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72R,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16IPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,I624M,P681R,A688T,Q779K,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,V36F,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,A623-,I624-,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482S,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,V143F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q675K,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,D111N,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,G842S,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,G184D,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 19 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182T,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,F817L,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 16 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 17 +[+16MPLF,R21T,T22N,S31P,S50L,F59L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 29 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182T,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,F817L,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 27 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A701V,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 29 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182T,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N370K,R403K,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,F817L,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 27 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H,N764K] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 27 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A701V,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,V1133I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,D936Y,S939F,K1086R,V1104L,I1114V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,+126F,I128-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,T22N,S50L,F59-,+60C,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446I,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P812L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T732I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,P85Q,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,F32-,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,G75A,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,K558N,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S98F,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V126F,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,G482S,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 21 +[N17M,+17P,+18FNFI,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,I844T,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,G72E,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,L118F,V127F,K147I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A829T,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,M153I,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211I,L212R,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,V785F,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N149-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,D796H,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H,D796Y] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346P,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,P337S,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,N532K,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,Y269H,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,D1118Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1153H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,W152R,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,Q613H,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72W,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,N61H,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,C1243Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,H49Y,S50L,F59S,H69-,V70-,I105V,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,L763F,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683W,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,S31-,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[R21T,T22N,N30T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,F486L,Q493E,E554K,A570V,P621S,N641I,V642-,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,S477N,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 21 +[R21T,S31-,S50L,H69-,V70-,V127F,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q628K,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,A623-,I624-,P681R,S939F,V1104L,T1116N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 16 +[L5F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445Q,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Q321R,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,Q493E,T547I,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,N148S,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,A958S,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N196S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 11 +[R21T,S50L,S60P,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,F543S,E554K,F559S,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V642G,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,A575S,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F486P,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,W152L,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[T20I,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[V3G,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S477N,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A831V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 13 +[R21T,S31-,R34C,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,Q787K,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,Q474R,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,I100M,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,C1248F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,E554K,A570V,P621S,T676N,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,Q134H,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 8 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,L176F,F186L,R190S,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,L560M,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K378N,R403K,V445H,N450D,L452W,L455S,F456L,T478R,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 7 +[+8T,L10-,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V90L,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,R34P,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T791K,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V83F,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S640Y,N641-,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 10 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 0/1 0.00000/0.00021 +0.02% +100.0% 1e+0 9 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,P812A,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A879S,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,L461I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 9265 1 0.0% 1/0 0.00022/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,S71F,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H]
last modified: Mon Jan 8 13:32 2024
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Questions or comments? Contact us at seq-info@lanl.gov.
Questions or comments? Contact us at seq-info@lanl.gov.
