COVID-19 Viral Genome Analysis Pipeline
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Frequency Changes in Common Forms
Last update: Oct 13, 2025
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SPIKE sequences: Exhaustive list of Last 60 days, Global, Do not break out by lineage
Compute mutations relative to XBB.1.5 baseline sequence
As new lineages emerge, there are often many sequences with many ambiguous base calls. Our pipeline filters out such sequences, and as a consequence we undercount the number of sequences in GISAID that have been specified as members of related Pango lineages. Our strategy, however, enables us to use strictly high quality sequences to identify and track the common forms in emerging lineages.
COMMON FORMS CHANGES FOR SPIKE WITH A GIVEN PANGO LINEAGE DESIGNATION
For each lineage, we show the most common forms of SPIKE, and we show the forms that are most significantly increasing or decreasing. Also shown is the Hamming distance (HD) between each form and the most common form in that lineage. Deletions relative to the baseline reference strain are indicated with a dash (e.g. the two amino acid deletion at positions 156-157 is indicated with 'E156-,F157-'), and insertions are denoted by a plus sign (e.g. an extra T at position 143 is written '+143T'). Abs Differences in later vs early fractions, expressed as percent. Relative Differences range between -100% and +100%, using formula: rel = 100*(later-early)/max(later,early) percent, applied to the early and later fractions. The p-value associated with increase or decrease is computed by Fisher's exact test, and is meant to be used only as a rough guide to the significance of the change. Since the computation is based on assumptions (such as independent and unbiased sampling) that may not hold in practice, the p-value should not be taken too literally. The first line of each lineage section indicates counts for the full lineage relative to all the sequences. 'Lineage Count' in this first line is actually the full sequence count. 'Form Count' in this first line is actually the full lineage count, and 'Form Pct' refers to lineage count relative to full sequence set.
We show all the forms.
[Note: Mutation strings are relative to baseline XBB.1.5].
This output is based on 12634 sequences sampled from 2025-08-07 to 2025-10-06
This total interval is split into two sub-intervals.
Total: 2025-08-07 to 2025-10-06 (12634)
Early: 2025-08-07 to 2025-08-26 (5976)
Later: 2025-08-27 to 2025-10-06 (6658)
Baseline XBB.1.5: [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
Pango Lineage Form Form Counts Fractions Differences Lineage Count Count Pct Early/Later Early/Later Abs Relative pval HD [Form as mutation string] N/A 12634 3231 25.6% 1339/1892 0.22406/0.28417 +6.01% +21.2% <1e-10 0 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] (consensus) N/A 12634 1085 8.6% 615/470 0.10291/0.07059 -3.23% -31.4% <1e-10 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1057 8.4% 673/384 0.11262/0.05767 -5.49% -48.8% <1e-10 4 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 369 2.9% 157/212 0.02627/0.03184 +0.56% +17.5% 6e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 320 2.5% 154/166 0.02577/0.02493 -0.08% -3.2% 8e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 148 1.2% 71/77 0.01188/0.01157 -0.03% -2.7% 9e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 147 1.2% 59/88 0.00987/0.01322 +0.33% +25.3% 8e-2 14 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 140 1.1% 78/62 0.01305/0.00931 -0.37% -28.7% 5e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 131 1.0% 49/82 0.00820/0.01232 +0.41% +33.4% 3e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 113 0.9% 64/49 0.01071/0.00736 -0.33% -31.3% 5e-2 16 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 110 0.9% 18/92 0.00301/0.01382 +1.08% +78.2% <1e-10 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 76 0.6% 26/50 0.00435/0.00751 +0.32% +42.1% 3e-2 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 71 0.6% 42/29 0.00703/0.00436 -0.27% -38.0% 6e-2 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 63 0.5% 10/53 0.00167/0.00796 +0.63% +79.0% 2e-7 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 63 0.5% 18/45 0.00301/0.00676 +0.37% +55.4% 3e-3 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 60 0.5% 12/48 0.00201/0.00721 +0.52% +72.1% 1e-5 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 59 0.5% 28/31 0.00469/0.00466 -0.00% -0.6% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 49 0.4% 21/28 0.00351/0.00421 +0.07% +16.4% 6e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 49 0.4% 11/38 0.00184/0.00571 +0.39% +67.7% 5e-4 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 48 0.4% 20/28 0.00335/0.00421 +0.09% +20.4% 5e-1 16 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 47 0.4% 27/20 0.00452/0.00300 -0.15% -33.5% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 46 0.4% 25/21 0.00418/0.00315 -0.10% -24.6% 4e-1 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 43 0.3% 21/22 0.00351/0.00330 -0.02% -6.0% 9e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 40 0.3% 17/23 0.00284/0.00345 +0.06% +17.7% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 40 0.3% 14/26 0.00234/0.00391 +0.16% +40.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 39 0.3% 24/15 0.00402/0.00225 -0.18% -43.9% 8e-2 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 38 0.3% 3/35 0.00050/0.00526 +0.48% +90.5% 2e-7 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 37 0.3% 3/34 0.00050/0.00511 +0.46% +90.2% 4e-7 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 37 0.3% 4/33 0.00067/0.00496 +0.43% +86.5% 3e-6 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K417T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 36 0.3% 26/10 0.00435/0.00150 -0.28% -65.5% 4e-3 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 33 0.3% 12/21 0.00201/0.00315 +0.11% +36.3% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,A67V,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 33 0.3% 17/16 0.00284/0.00240 -0.04% -15.5% 7e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 33 0.3% 10/23 0.00167/0.00345 +0.18% +51.6% 6e-2 11 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 32 0.3% 2/30 0.00033/0.00451 +0.42% +92.6% 8e-7 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 31 0.2% 2/29 0.00033/0.00436 +0.40% +92.3% 1e-6 14 +[+16MPLF,R21T,T22N,Y28F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,F175L,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 30 0.2% 14/16 0.00234/0.00240 +0.01% +2.5% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 30 0.2% 6/24 0.00100/0.00360 +0.26% +72.1% 3e-3 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 30 0.2% 11/19 0.00184/0.00285 +0.10% +35.5% 3e-1 1 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 29 0.2% 18/11 0.00301/0.00165 -0.14% -45.1% 1e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 29 0.2% 20/9 0.00335/0.00135 -0.20% -59.6% 2e-2 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 29 0.2% 11/18 0.00184/0.00270 +0.09% +31.9% 4e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 26 0.2% 11/15 0.00184/0.00225 +0.04% +18.3% 7e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 26 0.2% 4/22 0.00067/0.00330 +0.26% +79.7% 1e-3 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 26 0.2% 20/6 0.00335/0.00090 -0.24% -73.1% 3e-3 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 25 0.2% 10/15 0.00167/0.00225 +0.06% +25.7% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 12634 24 0.2% 19/5 0.00318/0.00075 -0.24% -76.4% 2e-3 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 24 0.2% 12/12 0.00201/0.00180 -0.02% -10.2% 8e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 23 0.2% 18/5 0.00301/0.00075 -0.23% -75.1% 3e-3 13 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 23 0.2% 16/7 0.00268/0.00105 -0.16% -60.7% 4e-2 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 23 0.2% 12/11 0.00201/0.00165 -0.04% -17.7% 7e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 22 0.2% 15/7 0.00251/0.00105 -0.15% -58.1% 6e-2 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 21 0.2% 6/15 0.00100/0.00225 +0.12% +55.4% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 20 0.2% 10/10 0.00167/0.00150 -0.02% -10.2% 8e-1 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 20 0.2% 1/19 0.00017/0.00285 +0.27% +94.1% 6e-5 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,G184A,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 19 0.2% 6/13 0.00100/0.00195 +0.09% +48.6% 2e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 19 0.2% 12/7 0.00201/0.00105 -0.10% -47.6% 2e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 19 0.2% 15/4 0.00251/0.00060 -0.19% -76.1% 9e-3 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 19 0.2% 8/11 0.00134/0.00165 +0.03% +19.0% 8e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 18 0.1% 9/9 0.00151/0.00135 -0.02% -10.2% 8e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 18 0.1% 7/11 0.00117/0.00165 +0.05% +29.1% 6e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 17 0.1% 6/11 0.00100/0.00165 +0.06% +39.2% 3e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 17 0.1% 9/8 0.00151/0.00120 -0.03% -20.2% 8e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 17 0.1% 11/6 0.00184/0.00090 -0.09% -51.0% 2e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 16 0.1% 8/8 0.00134/0.00120 -0.01% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 16 0.1% 9/7 0.00151/0.00105 -0.05% -30.2% 6e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 16 0.1% 11/5 0.00184/0.00075 -0.11% -59.2% 1e-1 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 15 0.1% 7/8 0.00117/0.00120 +0.00% +2.5% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,Q677L,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 15 0.1% 8/7 0.00134/0.00105 -0.03% -21.5% 8e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 15 0.1% 4/11 0.00067/0.00165 +0.10% +59.5% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,M177I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 15 0.1% 9/6 0.00151/0.00090 -0.06% -40.2% 4e-1 10 +[+16MPLF,T19V,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 15 0.1% 13/2 0.00218/0.00030 -0.19% -86.2% 3e-3 1 +[+16MSLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 15 0.1% 3/12 0.00050/0.00180 +0.13% +72.1% 4e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,L176F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 15 0.1% 12/3 0.00201/0.00045 -0.16% -77.6% 2e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 14 0.1% 2/12 0.00033/0.00180 +0.15% +81.4% 1e-2 13 +[+16MPLF,R21T,T22N,S50L,F59S,V62I,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 14 0.1% 5/9 0.00084/0.00135 +0.05% +38.1% 4e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,I402V,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T470I,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 14 0.1% 1/13 0.00017/0.00195 +0.18% +91.4% 2e-3 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 13 0.1% 4/9 0.00067/0.00135 +0.07% +50.5% 3e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 13 0.1% 7/6 0.00117/0.00090 -0.03% -23.1% 8e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 13 0.1% 3/10 0.00050/0.00150 +0.10% +66.6% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 13 0.1% 5/8 0.00084/0.00120 +0.04% +30.4% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 13 0.1% 3/10 0.00050/0.00150 +0.10% +66.6% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 13 0.1% 1/12 0.00017/0.00180 +0.16% +90.7% 4e-3 1 +[L8F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 13 0.1% 3/10 0.00050/0.00150 +0.10% +66.6% 1e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 13 0.1% 5/8 0.00084/0.00120 +0.04% +30.4% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 12 0.1% 6/6 0.00100/0.00090 -0.01% -10.2% 1e+0 12 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 11 0.1% 5/6 0.00084/0.00090 +0.01% +7.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T286I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 11 0.1% 7/4 0.00117/0.00060 -0.06% -48.7% 4e-1 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 11 0.1% 5/6 0.00084/0.00090 +0.01% +7.2% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 11 0.1% 6/5 0.00100/0.00075 -0.03% -25.2% 8e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 10 0.1% 3/7 0.00050/0.00105 +0.05% +52.3% 4e-1 14 +[T19V,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 10 0.1% 4/6 0.00067/0.00090 +0.02% +25.7% 8e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 10 0.1% 1/9 0.00017/0.00135 +0.12% +87.6% 2e-2 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,Q675H,P681R,S939F,A942T,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 10 0.1% 3/7 0.00050/0.00105 +0.05% +52.3% 4e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 10 0.1% 4/6 0.00067/0.00090 +0.02% +25.7% 8e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701V,P809S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 10 0.1% 1/9 0.00017/0.00135 +0.12% +87.6% 2e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 9 0.1% 3/6 0.00050/0.00090 +0.04% +44.3% 5e-1 11 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 9 0.1% 5/4 0.00084/0.00060 -0.02% -28.2% 7e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 9 0.1% 0/9 0.00000/0.00135 +0.14% +100.0% 4e-3 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946R,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 9 0.1% 9/0 0.00151/0.00000 -0.15% -100.0% 1e-3 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 9 0.1% 6/3 0.00100/0.00045 -0.06% -55.1% 3e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 9 0.1% 4/5 0.00067/0.00075 +0.01% +10.9% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 8 0.1% 7/1 0.00117/0.00015 -0.10% -87.2% 3e-2 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 8 0.1% 3/5 0.00050/0.00075 +0.02% +33.2% 7e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 8 0.1% 4/4 0.00067/0.00060 -0.01% -10.2% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 8 0.1% 6/2 0.00100/0.00030 -0.07% -70.1% 2e-1 5 +[L5F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 8 0.1% 2/6 0.00033/0.00090 +0.06% +62.9% 3e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N641K,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 8 0.1% 8/0 0.00134/0.00000 -0.13% -100.0% 2e-3 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,A846V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 8 0.1% 2/6 0.00033/0.00090 +0.06% +62.9% 3e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,E780Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 8 0.1% 1/7 0.00017/0.00105 +0.09% +84.1% 7e-2 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,N148T,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N641K,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 8 0.1% 8/0 0.00134/0.00000 -0.13% -100.0% 2e-3 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 8 0.1% 8/0 0.00134/0.00000 -0.13% -100.0% 2e-3 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 7 0.1% 5/2 0.00084/0.00030 -0.05% -64.1% 3e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219D,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 4/3 0.00067/0.00045 -0.02% -32.7% 7e-1 11 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 4/3 0.00067/0.00045 -0.02% -32.7% 7e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 3/4 0.00050/0.00060 +0.01% +16.4% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 6/1 0.00100/0.00015 -0.09% -85.0% 6e-2 10 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 7 0.1% 1/6 0.00017/0.00090 +0.07% +81.4% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 2/5 0.00033/0.00075 +0.04% +55.4% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 3/4 0.00050/0.00060 +0.01% +16.4% 1e+0 10 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 0/7 0.00000/0.00105 +0.11% +100.0% 2e-2 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 7 0.1% 3/4 0.00050/0.00060 +0.01% +16.4% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 7 0.1% 6/1 0.00100/0.00015 -0.09% -85.0% 6e-2 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 0/7 0.00000/0.00105 +0.11% +100.0% 2e-2 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 0/7 0.00000/0.00105 +0.11% +100.0% 2e-2 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,T500A,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 7 0.1% 0/7 0.00000/0.00105 +0.11% +100.0% 2e-2 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D88G,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 1/6 0.00017/0.00090 +0.07% +81.4% 1e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,H1101D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 3/4 0.00050/0.00060 +0.01% +16.4% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S] N/A 12634 7 0.1% 4/3 0.00067/0.00045 -0.02% -32.7% 7e-1 7 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 4/3 0.00067/0.00045 -0.02% -32.7% 7e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 1/6 0.00017/0.00090 +0.07% +81.4% 1e-1 13 +[+16MPLF,R21T,T22N,S31F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,P174S,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 7 0.1% 2/5 0.00033/0.00075 +0.04% +55.4% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,L189F,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 5/2 0.00084/0.00030 -0.05% -64.1% 3e-1 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 5/2 0.00084/0.00030 -0.05% -64.1% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 7 0.1% 1/6 0.00017/0.00090 +0.07% +81.4% 1e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 7 0.1% 1/6 0.00017/0.00090 +0.07% +81.4% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150E,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 0/6 0.00000/0.00090 +0.09% +100.0% 3e-2 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 0/6 0.00000/0.00090 +0.09% +100.0% 3e-2 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 0/6 0.00000/0.00090 +0.09% +100.0% 3e-2 10 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 0/6 0.00000/0.00090 +0.09% +100.0% 3e-2 13 +[+16MPLF,R21T,T22N,S50L,F59S,I68M,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 2/4 0.00033/0.00060 +0.03% +44.3% 7e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,I105V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 2/4 0.00033/0.00060 +0.03% +44.3% 7e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 4/2 0.00067/0.00030 -0.04% -55.1% 4e-1 23 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 1/5 0.00017/0.00075 +0.06% +77.7% 2e-1 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 6 0.0% 1/5 0.00017/0.00075 +0.06% +77.7% 2e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 3/3 0.00050/0.00045 -0.01% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 2/4 0.00033/0.00060 +0.03% +44.3% 7e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,L223S,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 5/1 0.00084/0.00015 -0.07% -82.0% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 4/2 0.00067/0.00030 -0.04% -55.1% 4e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,L54F,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 4/2 0.00067/0.00030 -0.04% -55.1% 4e-1 5 +[R21T,T22N,S31P,S50L,A67V,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 3/3 0.00050/0.00045 -0.01% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 2/4 0.00033/0.00060 +0.03% +44.3% 7e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,E780Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 3/3 0.00050/0.00045 -0.01% -10.2% 1e+0 14 +[N17M,+17P,T19F,T20N,R21F,+21I,Q23T,L24N,P25Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 4/2 0.00067/0.00030 -0.04% -55.1% 4e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 3/3 0.00050/0.00045 -0.01% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 3/3 0.00050/0.00045 -0.01% -10.2% 1e+0 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 4/2 0.00067/0.00030 -0.04% -55.1% 4e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218H,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 1/5 0.00017/0.00075 +0.06% +77.7% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,N148S,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 0/6 0.00000/0.00090 +0.09% +100.0% 3e-2 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 6 0.0% 6/0 0.00100/0.00000 -0.10% -100.0% 1e-2 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A260T,A264D,I332V,K356T,R403K,A435S,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 5/1 0.00084/0.00015 -0.07% -82.0% 1e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,N282S,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 6 0.0% 6/0 0.00100/0.00000 -0.10% -100.0% 1e-2 1 +[+16MPLF,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 3/2 0.00050/0.00030 -0.02% -40.2% 7e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 2/3 0.00033/0.00045 +0.01% +25.7% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 2/3 0.00033/0.00045 +0.01% +25.7% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A1078V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 3/2 0.00050/0.00030 -0.02% -40.2% 7e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 5 0.0% 2/3 0.00033/0.00045 +0.01% +25.7% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,W64L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 0/5 0.00000/0.00075 +0.08% +100.0% 6e-2 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,R78K,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 0/5 0.00000/0.00075 +0.08% +100.0% 6e-2 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 0/5 0.00000/0.00075 +0.08% +100.0% 6e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,D796H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 12634 5 0.0% 1/4 0.00017/0.00060 +0.04% +72.1% 4e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 1/4 0.00017/0.00060 +0.04% +72.1% 4e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446T,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 5/0 0.00084/0.00000 -0.08% -100.0% 2e-2 1 +[V3G,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 5/0 0.00084/0.00000 -0.08% -100.0% 2e-2 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 2/3 0.00033/0.00045 +0.01% +25.7% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,N532S,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 5 +[R21T,T22N,S31P,T33I,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 1/4 0.00017/0.00060 +0.04% +72.1% 4e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,E154Q,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 5/0 0.00084/0.00000 -0.08% -100.0% 2e-2 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 5/0 0.00084/0.00000 -0.08% -100.0% 2e-2 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,M177I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 1/4 0.00017/0.00060 +0.04% +72.1% 4e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 2/3 0.00033/0.00045 +0.01% +25.7% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 2/3 0.00033/0.00045 +0.01% +25.7% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 5/0 0.00084/0.00000 -0.08% -100.0% 2e-2 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 3/2 0.00050/0.00030 -0.02% -40.2% 7e-1 5 +[R21T,T22N,S31P,S50L,A67S,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 0/5 0.00000/0.00075 +0.08% +100.0% 6e-2 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,K206R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 2/3 0.00033/0.00045 +0.01% +25.7% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N440R,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 5/0 0.00084/0.00000 -0.08% -100.0% 2e-2 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 4/1 0.00067/0.00015 -0.05% -77.6% 2e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 5/0 0.00084/0.00000 -0.08% -100.0% 2e-2 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,A243V,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 5/0 0.00084/0.00000 -0.08% -100.0% 2e-2 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 1/4 0.00017/0.00060 +0.04% +72.1% 4e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 2/3 0.00033/0.00045 +0.01% +25.7% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 0/5 0.00000/0.00075 +0.08% +100.0% 6e-2 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,A893V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 5 0.0% 3/2 0.00050/0.00030 -0.02% -40.2% 7e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,Q1180K,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 1/4 0.00017/0.00060 +0.04% +72.1% 4e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,P384S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 5 0.0% 0/5 0.00000/0.00075 +0.08% +100.0% 6e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T95I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 0/4 0.00000/0.00060 +0.06% +100.0% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,V227L,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 0/4 0.00000/0.00060 +0.06% +100.0% 1e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,L176F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 27 +[S50L,F59S,H69-,V70-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,G482A,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,K77E,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 0/4 0.00000/0.00060 +0.06% +100.0% 1e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,R78K,V127F,K147E,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 0/4 0.00000/0.00060 +0.06% +100.0% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A924T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 0/4 0.00000/0.00060 +0.06% +100.0% 1e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,I569V,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218H,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219D,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D936N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 10 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 3 +[+16MPLF,R21T,T22N,S31P,T33I,S50L,H69-,V70-,V127F,M153K,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,S316A,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1088R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 10 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 0/4 0.00000/0.00060 +0.06% +100.0% 1e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147E,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,T250N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1263Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,T250I,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 0/4 0.00000/0.00060 +0.06% +100.0% 1e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,A1078T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 15 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 0/4 0.00000/0.00060 +0.06% +100.0% 1e-1 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478V,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S98F,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,M177R,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 11 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,+344S,R346-,K356T,R403K,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A1070V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147E,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,E154V,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 1/3 0.00017/0.00045 +0.03% +62.9% 6e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A1020S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,G261C,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 4 0.0% 3/1 0.00050/0.00015 -0.04% -70.1% 4e-1 1 +[+16TPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 7 +[R21T,T22N,L24S,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 2/2 0.00033/0.00030 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 3 +[+16MPLF,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 4 0.0% 4/0 0.00067/0.00000 -0.07% -100.0% 5e-2 2 +[+16MPLF,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L242F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S929T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 14 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,L118F,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 24 +[S31P,S50L,H69-,V70-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444S,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 13 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 11 +[+16MPLF,T19V,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1189F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,D138Y,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1188D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,R273T,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,V687I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L752V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,A942T,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 13 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157A,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,G1251A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 1 +[+16MPLF,R21T,T22N,S31L,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,V159I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L754F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,V143-,Y145-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441V,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148S,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T791I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150R,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529R,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,G482S,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,Q173H,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,P217S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 15 +[R21T,S31-,S50L,I68T,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 1 +[F2L,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,A575S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481R,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N370K,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,G268S,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Y145L,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,T259I,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 13 +[L8F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 2 +[F2L,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,A1078V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 2 +[L8F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 18 +[R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 16 +[L5F,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,+344S,R346-,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V,V1264M]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,N148T,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683W,S939F,P1143L,D1163Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,C1243F,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,L189F,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218H,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1070S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N641K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,W152R,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1260E]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L176F,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,V289I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,S205F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K986R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V367I,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1094I,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,T547I,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1259Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1230A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,E324Q,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,I468L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,N185D,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 3/0 0.00050/0.00000 -0.05% -100.0% 1e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,T761I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 0/3 0.00000/0.00045 +0.05% +100.0% 3e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 3 0.0% 1/2 0.00017/0.00030 +0.01% +44.3% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L176I,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 3 0.0% 2/1 0.00033/0.00015 -0.02% -55.1% 6e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,M153V,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 11 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,V227L,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,I670L,P681R,S939F,P1143L,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,M1229T]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S937T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,A243S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,F1103S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,F306L,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1168N]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,G446T,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,G446S,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21I,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,V62I,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,A1070T,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 35 +[S31P,S50L,H69-,V70-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,E554K,A570V,T572I,P621S,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 28 +[S50L,F59S,H69-,V70-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,E224Q,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L242I,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,H49Y,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 9 +[L5F,+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219D,H245N,A264D,I332V,+344S,R346-,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 17 +[N17M,+17P,T19F,T20N,R21F,+21I,Q23T,L24N,P25Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[T19I,L24-,P25-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A1070S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,Q787L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,Y204H,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,T33I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,A942T,P1143L,Q1201K,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,P82T,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,I1216V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680Y,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G261R,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,A123S,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A831T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,P251S,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S875A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147E,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,D215G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 11 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946R,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 17 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,Q677L,P681R,S939F,P1143L,P1162L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,L1141V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D111N,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,S680P,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G261V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,E180Q,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,V433I,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,G181E,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S640F,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,R190S,P209S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A1020V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T676P,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,S1170F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L242P,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,A67V,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,Y170H,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,E154Q,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,M177T,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1027A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 16 +[+16MPLF,R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V642G,P681R,P812L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,M177I,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T604I,P621S,P681R,S939F,A1078V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,T500A,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 3 +[+16MPLF,R21T,T22N,N30-,+31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,D111N,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A263E,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T859I,S939F,P1143L,K1157N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,E340Q,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 15 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,F888L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,V62F,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,P139L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,M153I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,R683Q,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,P217S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148Y,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 5 +[L18F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F135L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G1099S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148H,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,I1183V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 5 +[L8F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,V159I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPL,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,Y505H,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,F32Y,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1083Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16TPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,S943N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,E154Q,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,M153V,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481T,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,I210V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,R102K,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1199N]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,T33I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845T,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 16 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 16 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I794T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16KPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,T33I,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,P812S,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,M153I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 17 +[L5F,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[V16F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,P384S,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,S60F,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,W64R,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 6 +[R21T,T22N,S31L,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,Y28H,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16TPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,Y473F,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 3 +[+16TPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,Y473F,N481K,V483-,E484K,N487D,Q493E,A522T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[N17M,+17P,T19F,T20N,R21I,+21I,Q23T,L24N,P25Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,I670M,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,G482-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,A67S,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Y269N,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 3 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,F643-,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,T470I,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,S155I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,P251H,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,G482-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 21 +[N17I,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 10 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148S,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,F306L,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[F2L,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,S151I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,E654K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,N1135D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,A575S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500A,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,P139S,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T676I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S929I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,G261S,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 15 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,P217H,R237K,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T859I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 16 +[R21T,S31-,S50L,H69-,V70-,G72E,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,L1141V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339N,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 7 +[R21T,T22N,S31P,S50L,V62L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,I1225T]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,P521S,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,I68T,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,G1099D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[F2L,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,G482R,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16IPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,N164D,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,K1245R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T859I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688T,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S254P,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529M,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,R237M,H245N,A263T,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,A1174V,I1183V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,M731I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,T588A,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,R646P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 11 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 14 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,D1184Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T286I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A706V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,S1170F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1202K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150E,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688S,S929T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16KPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 18 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211I,+211G,V213-,R214-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,N556K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150E,S151G,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 7 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G72E,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339Y,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,R237K,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1073N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,S71F,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,N1178S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,N532S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478Q,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,D745A,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,I434V,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,H1101Q,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,S60F,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,N282S,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,P174S,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 15 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,K1255N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 11 +[+16MPLF,R21T,Q23R,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S810L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,T1120S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1233V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,T236S,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,N148Y,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,M153I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 16 +[L5F,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,C1250F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 16 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F186L,R190S,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,I909V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,Q173R,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 4 +[P9S,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,F186L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 14 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,T95I,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,R273K,I332V,N334K,K356T,R403K,V445R,N450D,L452W,L455S,F456L,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 1/1 0.00017/0.00015 -0.00% -10.2% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S256P,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 2/0 0.00033/0.00000 -0.03% -100.0% 2e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,G72E,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T723I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 2 0.0% 0/2 0.00000/0.00030 +0.03% +100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,D936Y,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,N616S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[L8F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,T523I,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S698L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,I1169F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,P209S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,I1216V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,E583Q,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,D936N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681S,M731I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,E780A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,A67V,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,D228H,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,I598V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V120F,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A783K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V83I,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,L141-,G142-,V143-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLS,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,Q836R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681-,+682L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,N556S,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,T478R,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,T430I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,L141W,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A831V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,F175L,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,H146-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V635A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,L54F,H69-,V70-,V127F,M153V,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,A243V,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,F65L,H66N,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,Y144N,Y145-,K150I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,D843G,A892V,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1127N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356M,R403K,K417T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q675L,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1088R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,D1139Y,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,L922S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,L176F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,A67V,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,I68M,H69-,V70-,V127F,F157S,R158G,G184S,T208M,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,E154D,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500A,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147E,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218E,H245N,A264D,V289I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G72R,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446I,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T124S,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,N703S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 30 +[S31-,S50L,H69-,V70-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 25 +[S31P,S50L,H69-,V70-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L,D1168G]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 41 +[S50L,H69-,V70-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,E554K,A570V,P621S,R765L,S939F,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 27 +[S31P,S50L,H69-,V70-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,D405N,R408S,K417N,N440K,V445P,G446S,N460K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 23 +[S31P,S50L,H69-,V70-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 36 +[S50L,F59S,H69-,V70-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,A435S,V445H,N450D,L452W,L455S,F456L,Q493E,E554K,A570V,P621S,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,S477N,T478K,E484A,F486P,F490S,H655Y,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 26 +[S50L,H69-,V70-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 23 +[S31P,S50L,H69-,V70-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16KPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529N,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,A243T,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S937L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,G1246S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,+344S,R346-,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,A879V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,V308I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G72E,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,P139T,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182I,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,R214H,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 25 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A942S,P1143F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[S31P,S50L,H69-,V70-,F157S,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1237I]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219D,H245N,A264D,I332V,+344S,R346-,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S673T,N679R,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,E619D,P621S,P681R,S939F,D1084G,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,F59L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,R273M,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,M153V,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,E154Q,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,G946R,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,F59-,+60F,H69-,V70-,V127F,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,L54F,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,F486L,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F486P,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16IPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529R,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,G482-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,G184S,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,S162N,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,T573I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A352S,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,A688V,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,V289L,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,T547I,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K417I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,A958D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,Y508F,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,P217S,H245N,S256L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T732I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,P812S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,A67S,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,N703S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,D1146Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,E918D,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,G842D,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,P251T,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S45F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,I105V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,N532T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T883I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q675R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L763S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182I,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,N282K,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[T19V,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,T236S,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701V,P809S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1228A]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q675H,P681R,S939F,A958S,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1073N,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 24 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 22 +[S50L,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,P217S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[S31P,S50L,H69-,V70-,V127L,M153I,F157S,R158G,K182R,G184V,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[L5F,S31P,S50L,H69-,V70-,V127F,F157A,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S704L,S939F,G946R,P1143L,A1174V]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,E154V,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 22 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 21 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,R214H,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,A522S,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,D936E,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,M731I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,F175Y,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,L1265I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,I410V,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,G181E,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,L1200F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182I,R190S,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[L7F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,I434V,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T676I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A263G,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681-,+682Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,T250I,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,T478R,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,D1127G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L,I1210V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[T19V,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,T236S,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,N532S,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I312M,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 82 +[P9L,R21T,P26L,A67V,H69-,V70-,T95I,I101T,C136-,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,H146-,K147-,N149-,F157S,N164K,S172F,K187T,N211-,L212I,A243-,L244-,P251S,I326V,G339Y,A348P,K356T,R403K,A435S,N440R,V445A,G446D,L452W,T478N,E484K,G496S,K529N,E554D,A575S,E583D,H625R,N641K,V642G,E654K,N679R,A688D,S704L,K795T,A852K,S939F,D1184E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,N440K,V445P,G446S,T478K,E484A,F486P,F490S,Y505H,N679K] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 23 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S50L,H69-,V70-,G72E,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 24 +[S50L,F59S,H69-,V70-,V127F,M153T,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 24 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 24 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,L189P,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,N556D,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L922F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[F2L,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,V47I,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1188K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A1070V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D88H,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339D,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150Q,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481E,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V367I,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S689R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,T33I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 20 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,Y144C,Y145-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T274I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,Y144N,Y145-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,E324Q,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H,D796Y] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,M153I,F157A,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445Y,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N164S,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,T547K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,H1083Y,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,N856S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,A688T,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,Y204H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,I587V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N440R,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,K444T,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219D,H245N,A264D,I332V,+344S,R346-,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,S1170Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A831T,S939F,T961M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,C1243S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,P1263L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,A67V,H69-,V70-,V127F,H146-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1177L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,G142Y,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,N856S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G72E,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1230A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A262D,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,R237M,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72W,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,I770V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A1070V,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150N,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1088R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147E,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,H1159R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A771S,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[V16I,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V622A,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N440R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,N440K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,S477N,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[+16MPLF,R21T,S31L,F32-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,Q836H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,G482S,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A263G,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59-,+60F,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V83F,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,G199C,N211-,L212I,V213G,L216F,G232C,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,F718L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,A623S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,R102K,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,I818V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554N,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478Q,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T778I,S939F,Q954Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H,Q954H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[V16I,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[+16MSLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,R683Q,S939F,A942T,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,E309A,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S256P,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,P1143L,E1195Q]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,L189F,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1073R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T73I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,A653V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680Y,P681R,S939F,P1143L,L1224F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,R646H,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,S680A,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V120F,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,D138Y,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1188D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S256L,A262V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,A575S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,A647V,E654K,P681R,S939F,A942V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,P217S,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,S162I,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A352S,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S71F,V127F,S155I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481R,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,C1248F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[S12F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,S151T,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,S151T,F157S,R158G,G184S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 20 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,L54F,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1020S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1146G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S640Y,N641-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1130L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,D228N,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,A899S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,N710K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,P85T,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1079S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F55L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,E702Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,R1091H,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Y674F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127L,M153I,F157S,R158G,K182R,G184V,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,P499S,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,P209H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[L5F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T108S,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,Q271K,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,N360H,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,P1143L,T1238N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T618I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,T63N,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A263G,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,G1167V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845S,S939F,P1143L,G1219V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L,S1239N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Q183E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1127G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[Q14H,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[L18F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N501Y,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,L1203F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,Q779R,I934V,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,Q926H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A783V,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,V1128I,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 10 +[R21T,T22N,S31P,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,S221W,H245N,A264D,R273M,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483R,E484-,Q493E,E554K,A570V,P621S,I624M,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,I834V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,D627A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,P174S,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,V143D,Y145-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,E156D,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[N17S,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,Q173H,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,K187N,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,N1187Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G252S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,Q52K,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,S98F,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,G932D,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,T33K,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,S221T,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,K97E,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V635A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[L5F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,S221T,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,Y28F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T778A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A879S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,A1174T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A942S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A899S,S939F,P1143L,K1191N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,I68T,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,M177V,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[V3G,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,N969K] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,I231T,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,S1242G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478Q,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[L18F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,Q677R,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,P139S,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,R273T,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,V1128F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R765H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678-,+679K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,H1159R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V120I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[L18F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A262V,A263V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,T478R,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,Y28H,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N641S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,D178G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,N185I,F186-,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1079T,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,Q173R,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,I105V,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[+16MPLF,R21T,T22N,S50L,F59S,H69S,S71-,G72-,L118F,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,D138H,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,T19V,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446T,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 10 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T385I,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N501Y,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,T33S,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S247G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I312V,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1146Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T676A,Q677H,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,A163V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,L242F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1020S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,D111N,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T638I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,T1009I,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,P174S,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,A522V,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,D627E,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Q134R,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S929N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147N,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,T33K,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,P1162R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218H,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,F59L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,I670M,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150N,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184I,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,Q954N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H,Q954H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,Q779K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MSLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,I1232T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,T259I,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,P809Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,G482-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,S155I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,L1200F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V642G,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,N801D,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,T1231A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,S155G,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677P,P681R,P807S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,Q926L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,L56S,H69-,V70-,V127F,N148K,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T108S,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,A288V,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L,E1182Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,N532S,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679M,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S94P,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,D138Y,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,K529N,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S810L,R847T,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 86 +[P9L,R21T,P26L,A67V,H69-,V70-,T95I,I101T,C136-,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,H146-,K147-,N149-,F157S,N164K,S172F,K187T,N211-,L212I,+214AS,+215TD,A243-,L244-,P251S,I326V,G339Y,A348P,K356T,R403K,A435S,N440R,V445A,G446D,L452W,T478N,E484K,G496S,K529N,E554D,A575S,E583D,H625R,N641K,V642G,E654K,N679R,A688D,S704L,K795T,A852K,S939F,D1184E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,N440K,V445P,G446S,T478K,E484A,F486P,F490S,Y505H,N679K] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1122M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 19 +[R21T,S31-,S50L,H69-,V70-,I101T,D111N,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 19 +[R21T,T22N,S50L,F59S,I68T,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P863S,S939F,G1099D,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69P,V70-,S71-,I100L,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V120I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,Y1215F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,E619D,P621-,V622-,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,S155I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,N914S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1045N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,N149-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[V6A,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,N556K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,A942S,G946R,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,A67V,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D88E,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,V341I,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,R237K,H245N,G252S,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,S477D,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,S680F,P681R,S939F,G946R,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1202A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,L176F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T676P,Q677R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[V11A,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,I105V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,D111N,V127F,H146-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,P139L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,I1081M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,E324Q,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,E340Q,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I326V,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,A27-,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,G482S,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,A1016S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,Q580H,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,G268C,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,K811R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147N,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,D420N,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,E654K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,G268S,I332V,K356T,T376S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,K558N,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,L754F,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,A67S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,V143F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,E281Q,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,D198H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,A123S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,D936Y,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,L1234F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,Y28H,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V382L,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1116N,P1143L,G1219C]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,E780Q,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621F,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,G268S,I332V,K356T,T376S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,R78M,V127F,F157S,R158G,K182R,R190S,K206R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 19 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T874I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[+16IF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T859I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21S,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,A123S,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,D808V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,E780Q,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,F643K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,M731I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,G181V,F186L,R190S,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N185-,F186-,K187-,N188-,L189-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,S494P,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 23 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S698L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,S680Y,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147E,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,F1121L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S689I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,V127F,F157S,R158G,F175-,M177-,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,V705F,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L242F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,T1027I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529R,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MSLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T732I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,Y37C,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V642G,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1129I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,N137K,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,I402V,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T470I,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,R634H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,A879V,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,T236S,H245N,T250I,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,D405K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N641K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,D405N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,M1050T,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,A67V,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S247I,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,N87D,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,G181R,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,K444T,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,N99S,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,D138Y,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[N17M,+17P,T19F,T20N,R21L,T22I,Q23I,L24T,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V642G,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 20 +[N17M,+17P,+18FI,R21-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,I203M,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,G798S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445L,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,E281Q,T284I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,R190K,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,T1027I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,K77R,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P812S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L752I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T76I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,+643P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,Y144H,Y145-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,A344S,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,A93S,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,Q677L,P681R,S939F,P1143L,D1153G,P1162L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,Y28H,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S247G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S640P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16KPLF,R21T,T22N,S31P,S50L,L54F,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,D138H,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,R246I,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,D138H,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,R246I,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,D796H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H,D796Y] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150E,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T716I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,T29I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,E340Q,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G72E,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,G446T,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475S,N481K,V483-,E484K,Q493E,N532S,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 20 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,E619D,P621-,V622-,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[L8F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,E96D,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,A829S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A892V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,G142N,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,V62F,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 19 +[R21T,T22N,S50L,F59S,H69-,V70-,T108I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701V,P809S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16TPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,V736I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1020V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,T500A,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,T29I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T73A,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,L179F,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,L699F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,I692F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1070V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S98F,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701V,P809S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S375-,T376-,F377-,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,S375F,T376A,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,I101M,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,N334K,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,G932S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339Y,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,G482A,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,H1088R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16KPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S689N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,A123D,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H,N764K] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Y145L,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,P209L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1188D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,G482-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31T,S50L,H69-,V70-,V127F,K150R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L,C1250Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,L189F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,A67V,H69-,V70-,V127F,F157L,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,A829T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,L1265F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,N30I,S31-,F32-,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,V62I,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,D796H,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H,D796Y] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T827K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,Q677L,P681R,S939F,P1143L,K1157R,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,N556K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75C,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,W258C,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677L,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339R,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,T73N,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16KPLF,R21I,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218K,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,G482-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L922F,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 20 +[S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S31P,T33I,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,D1163N]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N641K,S680P,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,V1129I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,Q23R,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,S940F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31P,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,Q957E,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,H69-,V70-,S151I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,A67S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,A435S,N440R,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 19 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,E156D,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445L,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1009I,P1143L,I1225L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,A67S,H69-,V70-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,A243V,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,S477N,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D111N,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S256T,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,E773Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L226F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,N532S,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478M,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,E619D,P621-,V622-,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21I,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,V615I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V622A,P681R,M740I,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,A520S,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,Q1201R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[L8F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148S,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,G181R,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 19 +[R21T,T22N,F59S,I68M,H69-,V70-,V120I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,A67V,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,S1170Y,G1219V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,K776R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,V622I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S247G,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,L54F,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,I231T,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 10 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1163G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S31F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,M1050I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,R214H,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,A522V,E554K,A570V,P621S,I624M,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,Y505H,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,A67S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1133I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,S155I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481R,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T732I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N164S,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S659T,P681R,M740I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,A435S,N440R,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,C1236F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,M731I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,D198H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P809Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K150R,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A893V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D843G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1168E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T859I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,L270I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16IPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L,E1195D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,T259I,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547I,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 19 +[R21T,T22N,S50L,F59S,A67V,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765L,S939F,P1143L,D1153Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,Q613H,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,E654K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 19 +[R21T,T22N,S50L,F59S,H69-,V70-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,T274A,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N657S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572N,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S247G,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A829T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,I1225V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,Y505H,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,L461P,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,E654K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,R190M,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1137I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,D111N,V127F,F157S,R158G,G184-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1163N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572S,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,I68T,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677H,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,Q52K,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S255P,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 19 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,M177I,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,Y505H,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,I569V,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,G838S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,Y269C,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,Q173R,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H,Q954H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[L5F,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 21 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R765H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,E96G,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688S,P812L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1068L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N196T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 19 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,T274A,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,P681R,I692F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,Q183H,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S659T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,V705F,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Y269H,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,I105V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,T250I,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[N17S,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1073M,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,K182E,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S884A,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,L118F,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,A647V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A893V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[T19V,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,A845S,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R847K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,S939F,H1101Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,Y160C,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,W64C,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,I670M,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,E180K,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,P217H,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,E309Q,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T676N,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L,Y1272H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218E,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,G142Y,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529N,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31H,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V83I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,D1165Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570-,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,G257D,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,G75V,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,R237M,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218H,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,G72E,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,S31-,S50L,H69-,V70-,V127F,H146-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,I870V,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A688T,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,V687I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,S680Y,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529N,E554K,A570V,T572I,P621S,R646P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V367I,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,N1178Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,I1225T,I1227V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T73N,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1163N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219D,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,A292T,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622A,Q675H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A871S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688T,A924T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,I68-,H69-,V127F,M153V,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,T573I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[+16MPLF,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,E154V,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,S1170P]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q677K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,G1219C]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,S71F,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,F79L,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T124I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152Q,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S31F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,I233T,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,R1091S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96K,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21N,T22-,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,S172F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLL,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N641K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,P174S,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,A647V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,Y145L,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,G700C,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,S60P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260T,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,E156D,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,L1200F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69Y,V70-,S71-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 54 +[T19L,Q52H,F157L,M177I,G184S,T385I,L452R,F456L,A688V]-[T19I,G446S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,A222S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,Q173R,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,P479L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,E156K,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,S162I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[Q14R,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,P139L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,H655Y,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,A771S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S98F,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S640Y,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,V642G,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218E,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A1078V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218H,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,D1084G,P1143L,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q675H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G75S,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,K814R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 21 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N185-,F186-,K187-,N188-,L189-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,E619D,P621-,V622-,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,P139S,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253V,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,N709S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,A27-,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,K1205N]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,D936Y,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 19 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T678I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150E,F157S,R158G,K182R,R190S,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 19 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P812L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,V445R,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,G181R,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,A163T,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 20 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V213G,L216F,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P812L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,I101V,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L,V1228A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V367I,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1165Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,K558N,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,N856S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,L54F,H69-,V70-,V127F,W152L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,N703T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,T478R,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S31P,T33I,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,R237M,H245N,A263T,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,A1174V,I1183V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257R,A264D,I332V,+344S,R346-,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,Q613E,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,V534I,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,Q183H,R190T,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,W152R,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1262A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S810L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,T573I,P621S,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,T259P,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1262A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L849I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,N148S,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[T19V,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MSLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,N751K,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,A243N,L244-,H245-,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,R646P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S640Y,N641-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,N148D,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,S1003I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,Y145P,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,A879V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,A879V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[L5F,+16MPLF,R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,T22N,H69-,V70-,V127F,F157S,R158G,G184S,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,M153I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H,Q954H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946R,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,N185I,F186-,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,S359N,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,R683L,S939F,P1143L,D1153A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,I235V,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,P174S,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,S31-,S50L,I68-,H69-,V127F,F157S,R158G,Q183H,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,D80Y,V127F,W152S,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K417T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263T,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679M,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680Y,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L,C1247S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,L517F,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1133I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,D1084G,P1143L,C1235F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,V722L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,M153V,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[L5F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182I,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,P681R,R683L,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,S31-,S50L,H69-,V70-,V127F,N148T,F157L,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R683W,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,R646S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T761A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1133I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L753S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,K150G,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Y269N,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,S939F,K1045R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,D80H,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,P621S,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[L5F,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S673T,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L,I1210V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T676N,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,V62L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,Q218H,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,T95N,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,L189P,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[R21T,S31-,S50L,H69-,V70-,V127F,N148T,F157L,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21I,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,F1095L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,T22N,S50L,T51A,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264Y,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,V47A,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 10 +[R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A831V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,S31-,S50L,H69-,V70-,V127F,F135S,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,T961M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,N30T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,R646P,P681R,S939F,P1143L,V1177L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[R21T,T22N,S31P,S50L,H69-,V70-,A123S,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,G482-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,P251L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,V62L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,P499H,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,L176F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1128I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,I1179V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L938I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677H,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,A123V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,K147Q,F157S,R158V,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,D1168Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,A93S,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G72W,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D80H,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,D138H,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,L54F,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1122M,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S71F,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,A522P,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,A222V,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,N1074S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T778S,S939F,V1104I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21S,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V193L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,S943N,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,R346T,L368I,K417N,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[H69-,V70-,V127F,R190S,N211-,L212I,V213G,L216F,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[F2L,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,N61I,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,G181V,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,V36A,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,T478R,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,S112P,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,V227L,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,N460K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T95I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,S98F,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16IPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,V327A,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T676I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,P809S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T676N,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I844V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,R683W,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T284I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,K529N,E554K,A570V,T604I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T274I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1199N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,R683Q,S939F,A942T,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,Q779E,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D950Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,F79L,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1248Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,+209S,N211G,L212-,V213-,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q675H,P681R,R683W,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,H1159N]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,V42I,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V367I,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,P1143L,D1165Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A706V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[L5F,+16MPLF,R21T,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,E702Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A899S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,K558N,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A688V,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1199H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677R,P681R,D830G,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,S151I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,I1225T]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N149-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q628E,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[Q14R,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 19 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V213G,L216F,H245N,A264D,I332V,K356T,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,N532D,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,D178N,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,S162I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A890S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,V534I,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31-,S50L,H69-,V70-,T76I,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,S31-,S50L,W64R,H69-,V70-,P85S,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,S1252F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,N532D,E554K,A570V,P621S,S680A,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,N148T,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T791I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,L118I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,R683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,Y144H,Y145-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,Q787L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,Q183H,G184S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1177A]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T95I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,F1156L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPL,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,K1157M]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946K,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,P209L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,D1127H,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622I,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,L1244P]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1009I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,G75V,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,G482-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,N334K,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T286I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,L546I,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263T,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Q134K,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G181V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L,K1191N]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16IPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182T,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,F643-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642I,P681R,S939F,P1143L,C1240Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,S112L,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 86 +[P9L,R21T,P26L,A67V,H69-,V70-,T95I,I101T,C136-,D138-,P139-,F140-,L141-,G142-,V143-,Y145-,H146-,K147-,N149-,F157S,N164K,S172F,K187T,N211-,L212I,+214AS,+215TD,A243-,L244-,P251S,I326V,G339Y,A348P,R403K,A435S,N440R,V445A,G446D,L452W,T478N,E484K,G496S,K529N,E554D,E583D,H625R,N641K,V642G,E654K,N679R,P681R,A688D,S704L,K795T,A852K,S939F,P1162R,D1184E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,T376A,N440K,V445P,G446S,T478K,E484A,F486P,F490S,Y505H,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,I100T,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,T470I,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S803L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,D178E,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,P1263R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,D53E,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A893T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,+209T,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,F306V,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N641K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,E471Q,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V90I,V127F,W152R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N501Y,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,R246T,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,D1153A]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A263S,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,N532K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,W64C,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,T761I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,S112L,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,D1084V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1184E]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S640F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[L18F,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,G482S,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,T761I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,A435S,V445H,G446-,G447-,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,S151N,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,D80Y,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I850V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,E154G,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A845V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,P209L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,F59L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1260Y]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,V193L,I210-,N211-,V213I,+213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A942S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPL,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[F2L,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T274I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A879T,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264H,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[L5F,+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,G476S,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L,Y1155H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,H69-,V70-,A123S,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,R273K,I332V,K356T,T376N,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,M153I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,F486L,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F486P,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,F1103S,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,I670M,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,E1150D]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,I231V,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[L5F,+16MPLF,R21T,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,L244S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A893V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1243F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150E,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[R21T,T22N,S31-,S50L,A67S,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L,L1224F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N641T,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,S151I,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,L849F,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,T500A,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219D,H245N,A264D,I332V,+344S,R346-,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260T,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[R21T,T22N,S31P,S50L,V62F,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,T19L,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,K444R,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D80N,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 22 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263S,A264D,I332V,K356T,R403K,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[L5F,+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,M153I,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,N282T,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,N501F,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N501Y,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,Q675K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 25 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1129L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143F,C1247F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,I1114T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K147N,F157S,R158G,K182R,N188S,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,L821V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,N532K,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,S112P,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,I834V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,I1114L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,G1085A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,T547I,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,T323I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,N148Y,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,P812L,S939F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,S31P,S50L,H69-,V70-,V127L,F157S,R158G,K182R,R190S,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N440R,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T307A,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,R408G,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 53 +[T19L,Q52H,D215V,T240I,F456L,E1258V]-[T19I,Y144-] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,I850L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,E780Q,S939F,P1143L,S1239G]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,W258L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,N556K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,D820N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31L,S50L,H69-,V70-,V127F,F157S,R158G,K182R,N185Y,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 21 +[+16MP,R21I,S50L,F59S,H69-,V70-,P85S,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455A,N481K,V483-,E484K,Y508H,E554K,A570V,T573I,P621S,P681R,I896T,S939F,N960S,A1087S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V83L,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,N532K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,Y505H,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T73I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,P1143L,I1169V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,L1200I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,D1084G,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,E1072V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A942V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T732I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T307S,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,F306L,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A879V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S640F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[V11I,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483R,E484-,Q493E,E516Q,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V120F,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,I101V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T95I,V127F,F157S,R158G,K182R,L189F,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1247Y]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,+344S,R346-,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G72W,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[N17M,+17P,T19F,T20N,R21L,T22I,Q23I,L24T,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A845S,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,N30I,S31-,F32-,S50L,A67V,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,R237M,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,A93S,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,A27-,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,I197V,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1020S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,Q183H,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,I1225V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,S221L,H245N,D253Y,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L,I1179V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1020S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152L,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,Y145L,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,S1170Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T307I,I332V,K356T,R403K,K444R,N450D,L452R,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[R21T,T22N,L24S,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P621S,P681R,S939F,P1143L,V1264L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 9 +[R21T,T22N,L24S,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 19 +[R21T,T22N,L24S,P25N,P26Q,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,L24S,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,L176F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[L5F,R21T,T22N,L24S,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,L24S,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,L24S,P25T,P26Q,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,L24S,P25N,P26Q,S31P,S50L,H69-,V70-,A123S,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[R21T,T22N,L24S,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,F175S,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N440R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[R21T,S31-,S50L,H69-,V70-,V127F,Y145N,H146-,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,R408N,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,T274I,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,I670L,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346K,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 18 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,A163V,L176I,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,T33A,S50L,H69-,V70-,S98F,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,L179I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 24 +[S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,F1075L,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 24 +[S50L,F59S,H69-,V70-,V127F,N148T,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946R,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529N,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262S,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1020S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[T20I,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,N185I,F186-,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,I1114V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[V6F,R21T,T22N,S31P,S50L,H69-,V70-,V83I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[V16I,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,V320F,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,D178N,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A684V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,R634H,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[L8F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,T573I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,G181V,F186L,R190S,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211T,L212G,V213-,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V367I,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1150V]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D88E,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,G257V,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,D979E,A1078V,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,N440K,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,D936H,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,N532S,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677H,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,D88A,V127F,F157S,R158G,G184S,T208M,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Q134K,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,T376V,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679T,P681R,S939F,V952F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[N17M,+17P,T19F,T20N,R21L,T22I,Q23I,L24T,P25N,P26Q,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,T29I,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1079S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157L,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,M153V,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 29 +[K182R,R190S,N211-,L212I,V213G,L216F,R403K,V445R,N481K,V483-,E484K,N487D,Q493E,P681R,S939F]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,S371F,S373P,S375F,T376A,K417N,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 26 +[H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,R403K,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L,E1195Q]-[V83A,G142D,H146Q,Q183E,V213E,G252V,L368I,K417N,N440K,V445P,G446S,N460K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,K1191M]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,T678I,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H,D796Y] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 18 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,Q134K,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,T376V,R403K,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679T,P681R,A879S,S939F,V952F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,H146-,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376S,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T376A,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,G261-,+264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,K97T,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S247I,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,G75V,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,N148S,F157S,R158G,N211-,L212I,V213G,L216F,T240I,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529T,E554K,A570V,T572I,T604I,P681R,S939F,P1143L,V1264L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 16 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,V1133L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683L,P809S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,T478E,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A263T,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683Q,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,V62L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,S31-,S50L,T51A,H69-,V70-,V127F,F157S,R158G,M177I,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,N532K,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,S673T,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,F888L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T286I,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31L,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,G446N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L,G1246D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,T874I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S254F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,A123V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,K150E,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547I,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A263V,A264D,I332V,K356T,N360H,R403K,A435S,V445R,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S659L,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,P384S,R403K,A435S,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 8 +[+16MPLF,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,F186C,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 11 +[R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 4 +[+16MPLF,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,D427N,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1228L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 3 +[+16MPLF,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,E1188D]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I326V,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,K529N,E554K,A570V,T572I,P621S,S680P,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,D1139N,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,R273S,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,R683L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,M153T,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,A475V,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N657K,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 6 +[+16MPLF,R21T,T22N,S50L,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,K1073M,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152R,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,I1018L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLC,R21T,T22N,S50L,F59S,H69-,V70-,V127F,H146-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1079S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,R78M,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,P809S,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A262V,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 7 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260T,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,S162G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1094I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,R78S,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,S151I,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,H146-,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,T430I,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L,D1146V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 16 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N185I,F186-,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,S221L,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,I101T,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,T376N,R403K,N450D,L452W,L455S,F456L,N481K,G482S,V483-,E484K,Q493E,E554K,A570V,P621S,S673T,N679R,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T376A,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 6 +[R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,I670M,P681R,S939F,V1122L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N440R,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,N440K,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,R765L,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,I434V,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,A27-,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[L24-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680Y,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S884F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,T500A,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,I834V,S939F,V1096A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,S205F,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483R,E484-,E554K,A570V,P621S,N679R,P681R,S939F,P1143L,D1184N]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,Y28F,S50L,F59S,H69-,V70-,V127F,F157S,R158G,F175L,G184S,N211-,L212I,V213G,L216F,H245N,G261C,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,P812L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,K97N,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,I692F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 9 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182G,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,L441R,K444R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,N679R,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680P,P681R,S939F,D1084G,E1111K,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,H1058Y,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,P330L,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,A623-,I624-,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S256L,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L,V1176F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1096A,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,E661D,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,D1153H]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,P272T,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S680F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642A,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441F,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,T299I,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,T415N,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,K1266R]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V407I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,D80Y,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,A1078T,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,A647V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,K1245N]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,S221T,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,S459F,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184R,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,G219S,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,A892V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,A701V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 17 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,+209F,N211G,L212-,V213-,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,T859I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,Q1208H]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,K776R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 12 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,D228H,H245N,A264D,I332V,K356T,R403K,A435S,V445R,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,P57S,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,G446S,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,Q1201K]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,S680F,P681R,S939F,P1143L,A1174V]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,G482D,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,D1153G]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,T645S,E654V,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,G639S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,E471Q,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,M153I,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621F,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143F,A1174S]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,P479R,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,G1267R]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 15 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,T500-,+501Y,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N501Y,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,Q607H,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 22 +[R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452R,L455S,F456L,T478I,N481K,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 14 +[L5F,+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,S255F,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 17 +[R21T,T22N,G35V,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,K97T,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,T1066N,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[R21T,T22N,S31P,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,H655Y,P681H,N764K] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S929N,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 15 +[+16MPLF,R21T,T22N,S50L,F59S,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,I1198T]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 14 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,T95I,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H,N764K] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,V1264F]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,Q474K,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,N30I,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,K182N,N211-,L212I,V213G,L216F,T240I,H245N,A264D,V308I,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,F186L,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,A701V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,L822F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,V143F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,C1236F]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V642G,Q677H,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,P681R,S939F,P1143L,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,V308L,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,T95I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,E154G,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A1078S,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,A701V,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,R1091H,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,E154V,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,E340Q,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,T19V,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,S161A,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,V1264L]-[T19I,V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S704L,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,N679R,P681R,S939F,T1027I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,V1230L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T768I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,R346I,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,V622F,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,T430I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,W152G,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,D1084G,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 11 +[+16MPLF,R21T,S31-,S50L,H69-,V70-,V127F,F157S,R158G,F186L,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,Q493E,E554K,A570V,P621S,N679R,P681R,S939F,K1086R,V1104L,P1143L,N1187S]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[L5F,+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,K835R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,S162R,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,Q321R,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 12 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,N532D,E554K,A570V,P621S,P681R,T791A,S939F,P1143L,T1273I]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A701T,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 10 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441R,N450D,L452W,L455S,F456L,A475V,N481K,V483-,E484K,N532D,E554K,A570V,P621S,P681R,T791A,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,A958S,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,K150N,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,G946R,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,Q677H,P681R,S939F,T1117I,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,E96D,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69S,S71-,G72-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 1/0 0.00017/0.00000 -0.02% -100.0% 5e-1 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,V445H,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,M1237I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,T478K,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPL,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A260S,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 1 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,D215A,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 4 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157P,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,T883I,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,N679K,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 5 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,V127F,F157S,R158G,K182R,R190S,+209S,N211G,L212-,V213-,L216F,H245N,A264D,I332V,L335F,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 13 +[+16MPLF,R21T,T22N,S50L,F59S,H69-,V70-,V127F,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,A435S,N450D,L452W,L455S,F456L,T478I,N481K,V483-,E484K,Q493E,T547K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,T478K,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 2 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,G75V,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,A688V,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H] N/A 12634 1 0.0% 0/1 0.00000/0.00015 +0.02% +100.0% 1e+0 3 +[+16MPLF,R21T,T22N,S31P,S50L,H69-,V70-,F92I,V127F,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,L441I,K444R,V445R,N450D,L452W,L455S,F456L,N481K,V483-,E484K,N487D,Q493E,E554K,A570V,T572I,P621S,P681R,S939F,P1143L,P1263L]-[V83A,H146Q,Q183E,V213E,G252V,L368I,V445P,E484A,F490S,P681H]
last modified: Mon Jan 8 13:32 2024
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Questions or comments? Contact us at seq-info@lanl.gov.
