COVID-19 Viral Genome Analysis Pipeline
Enabled by data from
Most common forms based on Pango lineage designations
Last update: Dec 6, 2023
Geographically local data, different time windows, and different proteins can be evaluated here
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SPIKE sequences: Short list of All days
Compute mutations relative to XBB.1.5 baseline sequence
As new lineages emerge, there are often many sequences with many ambiguous base calls. Our pipeline filters out such sequences, and as a consequence we undercount the number of sequences in GISAID that have been specified as members of related Pango lineages. Our strategy, however, enables us to use strictly high quality sequences to identify and track the common forms in emerging lineages.
COMMON FORMS OF SPIKE WITH A GIVEN PANGO LINEAGE DESIGNATION
For each lineage, we show the most common forms of SPIKE, as well as their counts within (and percentages of) the lineage. [Note that if a lineage contains several divergent forms, the consensus form might not be found among these common forms.] Also shown is the Hamming distance (HD) between each form and the most common form in that lineage. Deletions relative to the baseline reference strain are indicated with a dash (e.g. the two amino acid deletion at positions 156-157 is indicated with 'E156-,F157-'), and insertions are denoted by a plus sign (e.g. an extra T at position 143 is written '+143T'). [Note: Mutation strings are relative to baseline XBB.1.5].
We show the 5 most common forms. This output is based on sequences sampled from 2013-07-24 to 2023-11-28.
Baseline XBB.1.5: [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
Pango Lineage Form Form Lineage Count Count Pct HD [Form as mutation string] B.1.1.7 929775 591016 63.6% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.7 929775 23614 2.5% 1 +[H69-,V70-,A570D,T716I,S982A,D1118H,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.7 929775 20030 2.2% 1 +[L5F,H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.7 929775 10404 1.1% 1 +[H69-,V70-,W152R,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.7 929775 7721 0.8% 1 +[H69-,V70-,S98F,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.2 825359 628627 76.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2 825359 18681 2.3% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2 825359 17021 2.1% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2 825359 7505 0.9% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2 825359 5270 0.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.4 583628 350273 60.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4 583628 12534 2.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4 583628 10547 1.8% 1 +[T19R,T95I,D138H,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4 583628 8483 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,L1141F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4 583628 5361 0.9% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1 464613 355871 76.6% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1 464613 14885 3.2% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1 464613 6271 1.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1 464613 3899 0.8% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1 464613 3500 0.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.1 226818 166086 73.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.1 226818 3533 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.1 226818 3080 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.1 226818 2511 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.1 226818 1452 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.12.1 215043 166364 77.4% 0 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.12.1 215043 11833 5.5% 1 +[N164K,V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.1 215043 2618 1.2% 1 +[V213G,G339D,L452Q,Q493R,S704L,A879V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.1 215043 2406 1.1% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.12.1 215043 1963 0.9% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2 210092 146188 69.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2 210092 3178 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2 210092 2999 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2 210092 1926 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2 210092 1902 0.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.103 200745 108803 54.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.103 200745 24601 12.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103 200745 3112 1.6% 1 +[T19R,D80Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103 200745 1671 0.8% 1 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103 200745 1199 0.6% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43 188535 92975 49.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43 188535 27532 14.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43 188535 1976 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43 188535 1829 1.0% 1 +[V6F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43 188535 1525 0.8% 1 +[T19R,A67S,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1 174213 131552 75.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1 174213 7284 4.2% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1 174213 1668 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1 174213 1462 0.8% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1 174213 1253 0.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.5.1 162414 116697 71.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1 162414 4488 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1 162414 2585 1.6% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1 162414 1752 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1 162414 1744 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.617.2 158824 37576 23.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.617.2 158824 29569 18.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.2 158824 8113 5.1% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.2 158824 6670 4.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.2 158824 4505 2.8% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.44 158793 87881 55.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.44 158793 20305 12.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.44 158793 1210 0.8% 1 +[T19R,E156G,F157-,R158-,R214H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.44 158793 1026 0.6% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.44 158793 934 0.6% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122 129180 47816 37.0% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122 129180 14138 10.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122 129180 3566 2.8% 1 +[T19R,E156G,F157-,R158-,T240I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122 129180 2577 2.0% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122 129180 2520 2.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A879S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.9 128046 95747 74.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9 128046 6507 5.1% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9 128046 3455 2.7% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.9 128046 1108 0.9% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9 128046 554 0.4% 1 +[L179P,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1 113847 67891 59.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1 113847 12867 11.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1 113847 838 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1 113847 741 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1 113847 626 0.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] AY.3 111538 51525 46.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.3 111538 13741 12.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3 111538 4834 4.3% 1 +[T19R,V70I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3 111538 1872 1.7% 2 +[T19R,V70I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3 111538 1647 1.5% 2 +[T19R,V70I,E156G,F157-,R158-,M177I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.2 106940 54334 50.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.2 106940 6077 5.7% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.2 106940 2892 2.7% 2 +[L18F,E780Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.2 106940 2806 2.6% 1 +[Q677P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.2 106940 2508 2.3% 1 +[Q173K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5 100243 65262 65.1% 0 (consensus) XBB.1.5 100243 2674 2.7% 1 +[H146K]-[H146Q] XBB.1.5 100243 1507 1.5% 1 -[K417N] XBB.1.5 100243 914 0.9% 1 +[L5F] XBB.1.5 100243 464 0.5% 1 -[R408S] AY.25.1 95457 62597 65.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.25.1 95457 6554 6.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1 95457 951 1.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A846S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1 95457 792 0.8% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.1 95457 622 0.7% 1 +[T19R,V70F,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25 93231 34604 37.1% 0 +[T19R,S112L,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.25 93231 19124 20.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25 93231 8339 8.9% 1 +[T19R,S112L,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25 93231 4730 5.1% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25 93231 1367 1.5% 1 +[T19R,S112L,E156G,F157-,R158-,L452R,A522V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3 87106 65526 75.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3 87106 3548 4.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3 87106 1414 1.6% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3 87106 837 1.0% 2 +[V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3 87106 553 0.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.1.15 84332 65628 77.8% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.15 84332 2949 3.5% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15 84332 919 1.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,K854N,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15 84332 708 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.15 84332 618 0.7% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,L452R,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] B.1 81664 52499 64.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1 81664 1410 1.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1 81664 1242 1.5% 1 +[D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1 81664 846 1.0% 2 +[M153T,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1 81664 683 0.8% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.17.2 80839 58941 72.9% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.17.2 80839 5598 6.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,F643L,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.2 80839 1973 2.4% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.2 80839 518 0.6% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.2 80839 399 0.5% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.29 79751 58984 74.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.29 79751 1471 1.8% 1 +[T19R,T95I,E156G,F157-,R158-,R237S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29 79751 1449 1.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29 79751 1079 1.4% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29 79751 820 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,R408I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.5 72419 56700 78.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.5 72419 725 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5 72419 624 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.5 72419 437 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.5 72419 266 0.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.4.2 72005 50779 70.5% 0 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2 72005 1345 1.9% 1 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2 72005 997 1.4% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,H1083Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2 72005 692 1.0% 1 +[L5F,T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2 72005 665 0.9% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177 59883 23548 39.3% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177 59883 12711 21.2% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177 59883 3483 5.8% 3 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177 59883 1260 2.1% 2 +[A222V,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177 59883 959 1.6% 3 +[A222V,D1163Y,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1 58599 34625 59.1% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1 58599 1582 2.7% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,A688V,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1 58599 1491 2.5% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1 58599 1483 2.5% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1 58599 575 1.0% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,D427N,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.2 58295 51956 89.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.2 58295 1005 1.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,M153T,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.2 58295 515 0.9% 1 +[A67V,H69-,V70-,T76I,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.2 58295 334 0.6% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.2 58295 270 0.5% 1 +[A67V,H69-,V70-,D88E,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.100 58216 30444 52.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.100 58216 7739 13.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.100 58216 654 1.1% 1 +[T19R,T95I,E156G,F157-,R158-,T385I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.100 58216 626 1.1% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.100 58216 569 1.0% 1 +[T19R,P82T,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.5 46345 36276 78.3% 0 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.5 46345 806 1.7% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.5 46345 632 1.4% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,K1073T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5 46345 463 1.0% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5 46345 384 0.8% 1 +[L5F,H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1 45473 36312 79.9% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1 45473 936 2.1% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1 45473 846 1.9% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.1 45473 207 0.5% 1 +[V3G,H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1 45473 181 0.4% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.18 43752 18674 42.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.18 43752 18191 41.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.18 43752 934 2.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.18 43752 791 1.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.18 43752 387 0.9% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.5 42578 28029 65.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5 42578 3651 8.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5 42578 703 1.7% 1 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5 42578 427 1.0% 1 +[T19R,E156G,F157-,R158-,T376I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5 42578 345 0.8% 2 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,V772I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.10 41666 33369 80.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.10 41666 1068 2.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.10 41666 817 2.0% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10 41666 559 1.3% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10 41666 455 1.1% 1 +[V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6 40494 30947 76.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.6 40494 671 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.6 40494 435 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.6 40494 302 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6 40494 273 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1 40187 24049 59.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1 40187 799 2.0% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1 40187 366 0.9% 3 +[W152L,E484K,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1 40187 361 0.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1 40187 264 0.7% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.1.1 37058 28093 75.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.1 37058 899 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.1 37058 320 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BE.1.1 37058 291 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1 37058 268 0.7% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7 36456 25150 69.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7 36456 642 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7 36456 470 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7 36456 345 0.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7 36456 254 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BQ.1 36187 19238 53.2% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1 36187 6297 17.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1 36187 595 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1 36187 359 1.0% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1 36187 347 1.0% 1 +[H69-,V70-,V213G,P251H,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] AY.39 35046 16481 47.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39 35046 4161 11.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39 35046 1118 3.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39 35046 807 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39 35046 792 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.526 34681 15210 43.9% 0 +[L5F,T95I,D253G,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.526 34681 5986 17.3% 4 +[L5F,T95I,D253G,Q957R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.526 34681 2135 6.2% 2 +[L5F,T95I,D253G,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.526 34681 1051 3.0% 1 +[L5F,T95I,D253G,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.526 34681 791 2.3% 5 +[L5F,L18F,T95I,D253G,Q957R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.6 31224 24203 77.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.6 31224 436 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.6 31224 359 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.6 31224 181 0.6% 1 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6 31224 154 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.98 31010 16094 51.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.98 31010 1696 5.5% 2 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N,D1127G]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98 31010 1492 4.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98 31010 951 3.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98 31010 943 3.0% 1 +[T19R,E96V,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.17 30486 22597 74.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.17 30486 1027 3.4% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17 30486 724 2.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,S1147L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17 30486 315 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.17 30486 288 0.9% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.9.2 29922 16098 53.8% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.9.2 29922 3841 12.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2 29922 945 3.2% 1 +[T19R,A67V,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2 29922 348 1.2% 1 +[T19R,E156G,F157-,R158-,D215H,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2 29922 291 1.0% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.126 27968 10893 38.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,I850L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.126 27968 2892 10.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,I850L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.126 27968 491 1.8% 3 +[T19R,E156G,F157-,R158-,L452R,P681R,S689I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.126 27968 474 1.7% 1 +[T19R,T95I,E156G,F157-,R158-,E281Q,L452R,P681R,I850L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.126 27968 460 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.18 27494 22714 82.6% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.18 27494 570 2.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.18 27494 293 1.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.1.1.18 27494 208 0.8% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.18 27494 190 0.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] AY.26 27334 7199 26.3% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.26 27334 5538 20.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,N1074S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.26 27334 2582 9.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.26 27334 2196 8.0% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,N1074S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.26 27334 619 2.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,T547I,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160 26960 19966 74.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160 26960 386 1.4% 1 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160 26960 196 0.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160 26960 192 0.7% 1 +[A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160 26960 177 0.7% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4 26042 10699 41.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4 26042 7731 29.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4 26042 575 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4 26042 398 1.5% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,S640F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4 26042 382 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,D936N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.47 25965 14748 56.8% 0 +[T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.47 25965 5225 20.1% 1 +[T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.47 25965 364 1.4% 2 +[T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.47 25965 211 0.8% 1 +[L5F,T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.47 25965 111 0.4% 2 +[L5F,T19R,E156G,F157-,R158-,A222V,V289I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.1 25838 19431 75.2% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.1 25838 818 3.2% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.1 25838 715 2.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.1 25838 252 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,D1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.1 25838 240 0.9% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] B.1.429 24706 16100 65.2% 0 +[S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.429 24706 1981 8.0% 1 +[S13I,P26S,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.429 24706 263 1.1% 1 +[L5F,S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.429 24706 227 0.9% 1 +[S13I,W152C,A222V,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.429 24706 134 0.5% 1 +[S13I,W152C,L452R,L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.2 24247 13890 57.3% 0 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2.2 24247 2166 8.9% 1 +[S13T,T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.2 24247 1339 5.5% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,T299I,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.2 24247 1008 4.2% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1133I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.2 24247 930 3.8% 1 +[L18F,T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119 24235 8736 36.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.119 24235 4554 18.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P809S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119 24235 1921 7.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119 24235 1232 5.1% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P809S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119 24235 420 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P809S,G946R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120 21320 11446 53.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.120 21320 3186 14.9% 1 +[T19R,T51I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120 21320 532 2.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120 21320 303 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,V407I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120 21320 285 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,R1091H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.5.1.1 20954 12487 59.6% 0 +[Q52H,F456L] (consensus) EG.5.1.1 20954 1123 5.4% 1 +[Q52H,L455F,F456L] EG.5.1.1 20954 482 2.3% 1 +[Q52H,H146K,F456L]-[H146Q] EG.5.1.1 20954 276 1.3% 1 +[Q52H,F456L,S494P] EG.5.1.1 20954 196 0.9% 1 +[Q14R,Q52H,F456L] AY.98.1 20490 9842 48.0% 0 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.98.1 20490 4504 22.0% 1 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1 20490 421 2.1% 1 +[T19R,D80Y,E156G,F157-,R158-,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1 20490 301 1.5% 2 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.98.1 20490 233 1.1% 1 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,A942S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Unassigned 20113 5128 25.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] Unassigned 20113 1935 9.6% 5 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] Unassigned 20113 1743 8.7% 30 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Unassigned 20113 1145 5.7% 33 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Unassigned 20113 864 4.3% 35 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.5 19923 13122 65.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5 19923 519 2.6% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5 19923 389 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5 19923 333 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,N460S,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5 19923 270 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.121 19900 7583 38.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.121 19900 3276 16.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121 19900 683 3.4% 1 +[T19R,T95I,E156G,F157-,R158-,E180Q,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121 19900 221 1.1% 2 +[T19R,T95I,E156G,F157-,R158-,E180Q,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121 19900 191 1.0% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.1 19891 13486 67.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1 19891 854 4.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1 19891 835 4.2% 1 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1 19891 311 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1 19891 140 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.20 19848 5738 28.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.20 19848 2846 14.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.20 19848 2014 10.1% 1 +[T19R,T95I,K97E,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.20 19848 973 4.9% 2 +[T19R,T95I,K97E,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.20 19848 714 3.6% 2 +[T19R,T95I,K97E,E156G,F157-,R158-,L452R,P681R,D950N,V1104L,V1177I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.2 19628 8174 41.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.99.2 19628 4075 20.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.2 19628 1444 7.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.2 19628 192 1.0% 1 +[T19R,E156G,F157-,R158-,D178H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.2 19628 142 0.7% 1 +[T19R,E156G,F157-,R158-,L452R,S640F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.214 19354 11097 57.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.214 19354 2871 14.8% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.214 19354 701 3.6% 1 +[I720V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.214 19354 324 1.7% 1 +[S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.214 19354 319 1.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.519 19225 13178 68.5% 0 +[T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.519 19225 433 2.3% 1 +[L5F,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.519 19225 235 1.2% 1 +[T732A,E1258D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.519 19225 190 1.0% 2 +[A292S,T604A,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.519 19225 186 1.0% 1 +[P174S,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.6 18797 11225 59.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.6 18797 1569 8.3% 2 +[T19R,T22I,A67V,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.6 18797 444 2.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.6 18797 350 1.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,I1115V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.6 18797 247 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,V483F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127 18574 7036 37.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.127 18574 1354 7.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T859N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127 18574 1053 5.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127 18574 743 4.0% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.127 18574 624 3.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,D574N,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.27 18549 12063 65.0% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.27 18549 3029 16.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.27 18549 361 1.9% 1 +[T19R,E156G,F157-,R158-,L179F,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.27 18549 247 1.3% 1 +[L18F,T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.27 18549 207 1.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,A684S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.10 18123 13138 72.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.10 18123 805 4.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.10 18123 179 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.10 18123 176 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.10 18123 153 0.8% 2 +[W64C,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.125 17341 8314 47.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.125 17341 4197 24.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125 17341 292 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125 17341 291 1.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,A879S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.125 17341 208 1.2% 1 +[L18F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.16 17191 9607 55.9% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16 17191 355 2.1% 1 +[E180V,T478R]-[K417N,T478K] XBB.1.16 17191 256 1.5% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16 17191 169 1.0% 1 +[L5F,E180V,T478R]-[T478K] XBB.1.16 17191 164 1.0% 3 +[E180V,T478R,Q613H,Q675K,V1230A]-[T478K] BA.5.2.20 17031 11504 67.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.20 17031 467 2.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.20 17031 323 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.20 17031 241 1.4% 1 +[H69-,V70-,K147T,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.20 17031 220 1.3% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] P.1.14 16997 10686 62.9% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.14 16997 905 5.3% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.14 16997 341 2.0% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,I844V,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.14 16997 311 1.8% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.14 16997 277 1.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,L938F,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.20 16377 12894 78.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.20 16377 473 2.9% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.20 16377 148 0.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.20 16377 123 0.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.1.20 16377 106 0.6% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.46.6 16096 7205 44.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.6 16096 3434 21.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.6 16096 333 2.1% 1 +[T19R,H69Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.6 16096 300 1.9% 1 +[T19R,E156G,F157-,R158-,T323K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.6 16096 238 1.5% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.15.1 16094 13375 83.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.15.1 16094 300 1.9% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.1 16094 120 0.7% 1 +[A67V,H69-,V70-,T95I,D138N,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.1 16094 101 0.6% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.1 16094 77 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,I1081V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] AY.42 15953 3743 23.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.42 15953 3019 18.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T719I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.42 15953 2002 12.5% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T719I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.42 15953 1743 10.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.42 15953 268 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,T719I,T732I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75 15244 8489 55.7% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.75 15244 2463 16.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75 15244 167 1.1% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75 15244 141 0.9% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,T1231A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.75 15244 129 0.8% 1 +[T19R,E156G,F157-,R158-,A222V,P251L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.1 15089 11804 78.2% 0 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2.1 15089 359 2.4% 1 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,A899S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.1 15089 262 1.7% 1 +[T19R,V36F,G75R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.1 15089 206 1.4% 1 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,N1187S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.1 15089 197 1.3% 1 +[T19R,V36F,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,P809L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.5 15055 14505 96.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.5 15055 57 0.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.5 15055 46 0.3% 1 +[V213G,R214H,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.5 15055 34 0.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.5 15055 26 0.2% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23 14663 12681 86.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.23 14663 177 1.2% 1 +[V213G,G339D,Q493R,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23 14663 114 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.23 14663 111 0.8% 2 +[V213G,G339D,K356R,Q493R,A845G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23 14663 99 0.7% 1 +[K187R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.118 14506 8207 56.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.118 14506 2310 15.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.118 14506 476 3.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.118 14506 160 1.1% 1 +[V11I,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.118 14506 127 0.9% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HV.1 13537 9246 68.3% 0 +[Q52H,F157L,L452R,F456L] (consensus) HV.1 13537 460 3.4% 1 +[Q52H,H146K,F157L,L452R,F456L]-[H146Q] HV.1 13537 227 1.7% 1 +[Q52H,F157L,K444T,L452R,F456L] HV.1 13537 154 1.1% 1 +[Q52H,F157L,L452R,F456L,A1078S] HV.1 13537 144 1.1% 1 +[Q52H,F157L,L452R,F456L]-[H146Q] AY.23 13275 7496 56.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.23 13275 1404 10.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23 13275 353 2.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A845S,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23 13275 172 1.3% 3 +[T19R,H69-,V70-,E156G,F157-,R158-,D215N,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23 13275 142 1.1% 1 +[T19R,E156G,F157-,R158-,D215Y,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.9 13078 9653 73.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.9 13078 405 3.1% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.9 13078 261 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.9 13078 121 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.9 13078 91 0.7% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.6 13061 8450 64.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.6 13061 799 6.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.6 13061 149 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.6 13061 126 1.0% 1 +[H69-,V70-,Q183P,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.6 13061 124 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.30 12982 10197 78.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.30 12982 276 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.30 12982 224 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.30 12982 113 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.30 12982 98 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.39.1 12881 8311 64.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.1 12881 1655 12.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1 12881 197 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1 12881 163 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,V227I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1 12881 133 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,S813N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243 12852 4291 33.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.243 12852 2773 21.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243 12852 613 4.8% 2 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243 12852 374 2.9% 3 +[A520S,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.243 12852 373 2.9% 1 +[Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.2.1 12788 11081 86.7% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.1 12788 201 1.6% 1 +[V213G,T240P,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.1 12788 171 1.3% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.1 12788 101 0.8% 1 +[V213G,G339D,Q493R,E654Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.1 12788 96 0.8% 1 +[V213G,A262S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.22 12733 9583 75.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.22 12733 516 4.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.22 12733 314 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.22 12733 106 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.22 12733 93 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,L1244F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CH.1.1 12612 8477 67.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1 12612 140 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q1113K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1 12612 121 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1 12612 112 0.9% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1 12612 90 0.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T323A,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.33 12403 2662 21.5% 0 +[T19R,T29A,E156G,F157-,R158-,T250I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33 12403 2002 16.1% 2 +[T19R,T29A,E156G,F157-,R158-,T250I,T299I,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33 12403 1299 10.5% 1 +[T19R,T29A,E156G,F157-,R158-,T250I,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.33 12403 817 6.6% 3 +[T19R,T29A,E156G,F157-,R158-,T250I,T299I,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.33 12403 666 5.4% 1 +[T19R,T29A,E156G,F157-,R158-,T250I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258 12082 5481 45.4% 0 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258 12082 1680 13.9% 2 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258 12082 280 2.3% 3 +[N439K,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258 12082 270 2.2% 2 +[H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258 12082 217 1.8% 1 +[H69-,V70-,N439K,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.21 12057 9282 77.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.21 12057 669 5.5% 1 +[A222V,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.21 12057 471 3.9% 1 +[A222V,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.21 12057 135 1.1% 1 +[W64C,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.21 12057 129 1.1% 1 +[G181R,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.5.1 11950 7213 60.4% 0 +[Q52H,F456L] (consensus) EG.5.1 11950 324 2.7% 1 +[Q52H,H146K,F456L]-[H146Q] EG.5.1 11950 215 1.8% 1 +[T19L,Q52H,F456L]-[T19I] EG.5.1 11950 157 1.3% 1 +[Q52H,L455F,F456L] EG.5.1 11950 98 0.8% 2 +[Q52H,H146K,G261V,F456L]-[H146Q] BA.5.1.23 11931 8675 72.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.23 11931 318 2.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.23 11931 156 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.23 11931 118 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.23 11931 92 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A879S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.1 11654 10260 88.0% 0 +[V213G,G339D,Q493R,Q677E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.1 11654 100 0.9% 1 +[V213G,G339D,Q493R,Q677E,R847K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.1 11654 74 0.6% 1 +[V213G,G339D,Q493R,Q677E,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.1 11654 67 0.6% 1 +[V213G,G339D,Q493R,Q677E,R1014K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.1 11654 56 0.5% 1 +[L5F,V213G,G339D,Q493R,Q677E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.221 11592 8371 72.2% 0 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.221 11592 332 2.9% 1 +[S98F,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221 11592 112 1.0% 1 +[S98F,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221 11592 98 0.8% 1 +[S98F,K182R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221 11592 85 0.7% 2 +[S98F,A1078S,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.1 11388 5771 50.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.3.1 11388 2328 20.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.1 11388 178 1.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A846V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.1 11388 125 1.1% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,A701V,A846V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.1 11388 116 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.14 10741 8921 83.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.14 10741 134 1.2% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.14 10741 133 1.2% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.14 10741 88 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.14 10741 71 0.7% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.5.1.1 10706 8268 77.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.1 10706 162 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.1 10706 117 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.1 10706 106 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.1 10706 86 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.117 10635 5882 55.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.117 10635 1414 13.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.117 10635 275 2.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.117 10635 158 1.5% 1 +[T19R,T95I,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.117 10635 113 1.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1199N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.637 10513 5620 53.5% 0 +[D80G,F157S,L452R,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.637 10513 859 8.2% 1 +[D80G,F157S,L452R,T791I,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.637 10513 356 3.4% 1 +[D80G,S155R,F157S,L452R,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.637 10513 289 2.7% 1 +[D80G,F157S,L452R,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.637 10513 169 1.6% 2 +[H69Y,D80G,F157S,L452R,T791I,T859N,D950H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.5 10272 8223 80.1% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.5 10272 224 2.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.5 10272 118 1.1% 1 +[T19R,E156G,F157-,R158-,L452R,E583D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.5 10272 115 1.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.5 10272 109 1.1% 1 +[T19R,E156G,F157-,R158-,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HK.3 10229 6104 59.7% 0 +[Q52H,L455F,F456L] (consensus) HK.3 10229 201 2.0% 1 +[Q52H,H146K,L455F,F456L]-[H146Q] HK.3 10229 159 1.6% 1 +[Q52H,P174S,L455F,F456L] HK.3 10229 119 1.2% 1 +[Q52H,L455F,F456L,P809S] HK.3 10229 77 0.8% 1 +[L5F,Q52H,L455F,F456L] B.1.351 10207 2906 28.5% 0 +[D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.351 10207 2296 22.5% 1 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351 10207 434 4.3% 2 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351 10207 402 3.9% 1 +[D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351 10207 196 1.9% 2 +[L18F,D80A,D215G,L242-,A243-,L244-,P384L,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.69 9965 3872 38.9% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.69 9965 2635 26.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.69 9965 818 8.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.69 9965 196 2.0% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.69 9965 127 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.15 9917 8247 83.2% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.15 9917 269 2.7% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.15 9917 151 1.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.15 9917 97 1.0% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.15 9917 53 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,V826L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XBB.1 9853 5831 59.2% 0 +[F486S]-[F486P] (consensus) XBB.1 9853 323 3.3% 1 +[F486S]-[K417N,F486P] XBB.1 9853 167 1.7% 1 +[H146K,F486S]-[H146Q,F486P] XBB.1 9853 108 1.1% 1 +[F486S]-[G142D,F486P] XBB.1 9853 97 1.0% 4 -[S477N,T478K,E484A,F486P] B.1.1.284 9587 3747 39.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.284 9587 3580 37.3% 1 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.284 9587 486 5.1% 3 +[M153T,G184S,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.284 9587 185 1.9% 2 +[M153T,P793S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.284 9587 135 1.4% 2 +[M153T,S255Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.1.5.1 9551 6342 66.4% 0 +[F456L,T478R,A701V]-[T478K] (consensus) FL.1.5.1 9551 182 1.9% 1 +[H146K,F456L,T478R,A701V]-[H146Q,T478K] FL.1.5.1 9551 144 1.5% 1 +[F456L,T478R,E554K,A701V]-[T478K] FL.1.5.1 9551 100 1.0% 1 +[F456L,T478R,A701V]-[K417N,T478K] FL.1.5.1 9551 84 0.9% 1 +[L5F,F456L,T478R,A701V]-[T478K] BA.2.18 9513 7886 82.9% 0 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.18 9513 202 2.1% 1 +[V213G,S254F,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.18 9513 184 1.9% 1 +[L176F,V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.18 9513 180 1.9% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.18 9513 76 0.8% 1 +[L5F,V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] B.1.427 9388 4531 48.3% 0 +[S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.427 9388 1723 18.4% 1 +[S13I,W152C,W258L,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.427 9388 493 5.3% 1 +[S13I,W152C,L452R,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.427 9388 158 1.7% 1 +[P9L,S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.427 9388 99 1.1% 1 +[L5F,S13I,W152C,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.21 9268 7623 82.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.21 9268 103 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1116N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.21 9268 98 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.21 9268 90 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.21 9268 68 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.4.6 9218 6232 67.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.6 9218 714 7.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.6 9218 501 5.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.6 9218 287 3.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.6 9218 120 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,A222S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.3 9164 6116 66.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3 9164 115 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.3 9164 83 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N481K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3 9164 70 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,P631S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3 9164 54 0.6% 1 +[K147E,W152R,F157L,I210V,V213G,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.2.29 9162 8134 88.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.29 9162 121 1.3% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.29 9162 96 1.0% 1 +[V213G,G339D,Q493R,N703H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.29 9162 34 0.4% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.29 9162 31 0.3% 1 +[V213G,G339D,Q493R,A845S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.36 9108 4965 54.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.36 9108 982 10.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36 9108 744 8.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36 9108 157 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36 9108 122 1.3% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.1 9024 6718 74.4% 0 +[W152L,E484K,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) R.1 9024 308 3.4% 1 +[W152L,E484K,G769V,K795N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.1 9024 277 3.1% 1 +[W152L,E484K,G769V,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.1 9024 118 1.3% 1 +[W152L,E484K,N751D,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] R.1 9024 117 1.3% 1 +[W152L,S255F,E484K,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.26 8952 5278 59.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.26 8952 925 10.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.26 8952 343 3.8% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.26 8952 132 1.5% 1 +[T22I,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.26 8952 100 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.10 8821 5386 61.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.10 8821 687 7.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.10 8821 141 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.10 8821 115 1.3% 3 +[L5F,I68-,H69-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.10 8821 114 1.3% 1 +[H69-,V70-,Y145H,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.9 8565 5944 69.4% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.9 8565 412 4.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9 8565 190 2.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9 8565 145 1.7% 1 +[T19R,E156G,F157-,R158-,L189F,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9 8565 91 1.1% 1 +[T19R,D138Y,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.24 8448 7400 87.6% 0 +[V213G,G339N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.24 8448 103 1.2% 1 +[L5F,V213G,G339N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.24 8448 93 1.1% 1 +[V213G,G339N,Q493R,I844V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.24 8448 49 0.6% 2 +[F157S,V213G,G339N,Q493R,V1264M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.24 8448 46 0.5% 1 +[V213G,G339N,Q493R,D1153Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.113 8305 4947 59.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.113 8305 907 10.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.113 8305 81 1.0% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.113 8305 80 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] AY.113 8305 51 0.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.5 8214 5151 62.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.5 8214 304 3.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.5 8214 113 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D796H,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.5 8214 113 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,G769V,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.5 8214 105 1.3% 1 +[L18F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1259Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.16.6 8071 5674 70.3% 0 +[E180V,F456L,T478R]-[T478K] (consensus) XBB.1.16.6 8071 279 3.5% 1 +[H146K,E180V,F456L,T478R]-[H146Q,T478K] XBB.1.16.6 8071 197 2.4% 1 +[E180V,L455F,F456L,T478R]-[T478K] XBB.1.16.6 8071 84 1.0% 1 +[E180V,F456L,T478R]-[K417N,T478K] XBB.1.16.6 8071 70 0.9% 1 +[E180V,F456L,T478R,L938F]-[T478K] D.2 7932 6784 85.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) D.2 7932 205 2.6% 1 +[V1068F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.2 7932 135 1.7% 1 +[T632N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.2 7932 79 1.0% 1 +[A930V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] D.2 7932 73 0.9% 1 +[S698L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.14 7921 5178 65.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.14 7921 1084 13.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.14 7921 108 1.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.14 7921 81 1.0% 2 +[T19R,E156G,F157-,R158-,A348S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.14 7921 49 0.6% 1 +[T19R,E156G,F157-,R158-,L452R,T547I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.21 7861 5539 70.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.21 7861 328 4.2% 1 +[H69-,V70-,H146Y,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.21 7861 85 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1137I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.21 7861 78 1.0% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.21 7861 76 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.119.2 7843 4407 56.2% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.119.2 7843 895 11.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119.2 7843 749 9.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119.2 7843 184 2.3% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.119.2 7843 107 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,G181V,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.36 7646 5789 75.7% 0 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.36 7646 280 3.7% 1 +[I68T,V213G,G339D,Q493R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.36 7646 235 3.1% 1 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.36 7646 93 1.2% 2 +[I68T,V213G,Y248H,G339D,Q493R,T791I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.36 7646 57 0.7% 1 +[I68T,T73N,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.1 7603 5992 78.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.1 7603 125 1.6% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.1 7603 105 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BF.1 7603 97 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1009I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.1 7603 72 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.18 7529 4960 65.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.18 7529 448 6.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.18 7529 169 2.2% 1 +[H69-,V70-,V213G,Y248H,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.18 7529 75 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.18 7529 67 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] XBB.1.9.1 7511 4309 57.4% 0 (consensus) XBB.1.9.1 7511 155 2.1% 1 +[H146K]-[H146Q] XBB.1.9.1 7511 97 1.3% 1 +[T478R]-[T478K] XBB.1.9.1 7511 93 1.2% 1 -[K417N] XBB.1.9.1 7511 88 1.2% 1 +[L5F] AY.129 7469 3766 50.4% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.129 7469 1906 25.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.129 7469 168 2.2% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.129 7469 146 2.0% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,D950N,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.129 7469 38 0.5% 1 +[P9S,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.3 7464 5695 76.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.3 7464 228 3.1% 1 +[H69-,V70-,V213G,I231T,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.3 7464 145 1.9% 1 +[H69-,V70-,V213G,S254F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.3 7464 78 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.3 7464 49 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BQ.1.1.4 7332 4520 61.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.4 7332 643 8.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.4 7332 143 2.0% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q675H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.4 7332 127 1.7% 1 +[H69-,V70-,W152R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.4 7332 70 1.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A701S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.2 7205 4677 64.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.2 7205 249 3.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2 7205 177 2.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2 7205 122 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2 7205 111 1.5% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] C.37 7204 3673 51.0% 0 +[G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.37 7204 307 4.3% 1 +[G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,Q675H,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.37 7204 216 3.0% 1 +[G75V,T76I,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,I714V,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.37 7204 102 1.4% 13 +[T63-,W64-,F65-,H66-,A67-,H69-,V70-,S71-,G72-,T73-,N74-,G75-,T76-,R246N,S247-,Y248-,L249-,T250-,P251-,G252-,D253-,L452Q,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.37 7204 95 1.3% 8 +[G75V,T76I,L452Q,T859N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.54 7163 4235 59.1% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.54 7163 1216 17.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.54 7163 72 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.54 7163 65 0.9% 1 +[T19R,T22I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.54 7163 51 0.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,N777S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.13 6969 5993 86.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.13 6969 162 2.3% 1 +[V213G,G339D,Q493R,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.13 6969 76 1.1% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.13 6969 75 1.1% 1 +[M153I,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.13 6969 35 0.5% 1 +[V213G,G339D,Q493R,D1146H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2 6959 6254 89.9% 0 +[V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.2 6959 55 0.8% 1 +[V213G,G339D,K356R,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2 6959 42 0.6% 29 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.2.2 6959 30 0.4% 1 +[L176F,V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2 6959 29 0.4% 1 +[L5F,V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.234 6937 4134 59.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.234 6937 492 7.1% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.234 6937 354 5.1% 3 +[G142S,E180V,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.234 6937 180 2.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.234 6937 138 2.0% 4 +[G142S,E180V,Q677H,S940F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34 6913 3435 49.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.34 6913 1164 16.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34 6913 151 2.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34 6913 103 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,A1016V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34 6913 99 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.28 6863 3416 49.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.28 6863 1572 22.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A701S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.28 6863 162 2.4% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,A701S,D820E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.28 6863 142 2.1% 2 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.28 6863 76 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.621 6848 3135 45.8% 0 +[T95I,+143T,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.621 6848 492 7.2% 1 +[T95I,+143T,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621 6848 362 5.3% 1 +[T95I,+143T,Y144S,Y145N,R346K,E484K,D950N,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621 6848 214 3.1% 1 +[T95I,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621 6848 138 2.0% 1 +[T95I,+143T,Y144S,Y145N,R346K,E484K,T572I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.5.1.3 6832 5117 74.9% 0 +[H69-,V70-,V213G,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.3 6832 170 2.5% 1 +[H69-,V70-,V213G,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.3 6832 110 1.6% 1 +[H69-,V70-,V213G,D215V,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.3 6832 88 1.3% 1 +[L5F,H69-,V70-,V213G,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.3 6832 73 1.1% 1 +[H69-,V70-,V213G,V289I,G339D,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.1 6800 5216 76.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.4.1 6800 151 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.1 6800 93 1.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.1 6800 63 0.9% 2 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4.1 6800 53 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D745G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBF 6797 5083 74.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) XBF 6797 87 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G446N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S] XBF 6797 65 1.0% 1 +[W64L,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF 6797 47 0.7% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] XBF 6797 44 0.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L1224V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] BF.11 6795 4769 70.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.11 6795 112 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q607L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11 6795 104 1.5% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11 6795 83 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11 6795 81 1.2% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.258.17 6653 4995 75.1% 0 +[H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.17 6653 126 1.9% 1 +[P26L,H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.17 6653 65 1.0% 1 +[H69-,V70-,L189F,S256P,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.17 6653 56 0.8% 1 +[H69-,V70-,L189F,N439K,V772I,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.17 6653 52 0.8% 1 +[L5F,H69-,V70-,L189F,N439K,V772I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46 6580 3535 53.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46 6580 590 9.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46 6580 161 2.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,K835R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46 6580 156 2.4% 1 +[T19R,E132A,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46 6580 87 1.3% 2 +[T19R,T20I,E156G,F157-,R158-,L452R,S640F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.8 6477 5997 92.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.8 6477 79 1.2% 1 +[V213G,G339D,Q493R,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.8 6477 34 0.5% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.8 6477 20 0.3% 1 +[V83F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.8 6477 18 0.3% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BC.1 6381 5803 90.9% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BC.1 6381 74 1.2% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,M153T,N211-,L212I,+214EPE,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BC.1 6381 67 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BC.1 6381 31 0.5% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BC.1 6381 24 0.4% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,I233V,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] EG.5.1.3 6278 4588 73.1% 0 +[Q52H,F456L] (consensus) EG.5.1.3 6278 142 2.3% 1 +[Q52H,H146K,F456L]-[H146Q] EG.5.1.3 6278 69 1.1% 2 +[Q52H,L455F,F456L,S704L] EG.5.1.3 6278 50 0.8% 1 +[Q52H,F456L]-[Y144-] EG.5.1.3 6278 38 0.6% 1 +[Q52H,F456L]-[K417N] BA.2.56 6262 4454 71.1% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.56 6262 271 4.3% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.56 6262 182 2.9% 1 +[V213G,R214L,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.56 6262 103 1.6% 1 +[V213G,G339D,L452M,Q493R,Q787H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.56 6262 102 1.6% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] B.1.438.1 6241 3694 59.2% 0 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.438.1 6241 632 10.1% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.1 6241 563 9.0% 1 +[A653V,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.1 6241 206 3.3% 1 +[I233V,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.438.1 6241 153 2.5% 1 +[Q613H,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.5 6211 4137 66.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.5 6211 194 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.5 6211 105 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,M1229T,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.5 6211 74 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.5 6211 68 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1263Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.111 6210 4036 65.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.111 6210 314 5.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.111 6210 205 3.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.111 6210 120 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,N354K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.111 6210 108 1.7% 3 +[T19R,T95I,E156G,F157-,R158-,N211-,L212I,L452R,P681R,D950N,V1094I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.2 6088 4761 78.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.2 6088 126 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.2 6088 83 1.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.2 6088 71 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1250Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.2 6088 64 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.9 6087 3862 63.4% 0 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.9 6087 215 3.5% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.9 6087 157 2.6% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.9 6087 115 1.9% 1 +[H69-,V70-,V213G,S256L,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.9 6087 72 1.2% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,N460H,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.2 6049 4193 69.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2 6049 138 2.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2 6049 82 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.2 6049 54 0.9% 1 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2 6049 50 0.8% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BA.5.2.12 6034 4138 68.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.12 6034 897 14.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.12 6034 71 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,E1202A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.12 6034 44 0.7% 1 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.12 6034 41 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.12 5934 4159 70.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.12 5934 1099 18.5% 1 +[A222V,K1073T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.12 5934 184 3.1% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.12 5934 105 1.8% 1 +[A222V,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.12 5934 28 0.5% 1 +[G181V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.37 5918 5052 85.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.37 5918 117 2.0% 1 +[V213G,V227L,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.37 5918 78 1.3% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.37 5918 74 1.3% 1 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.37 5918 64 1.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.27 5878 4629 78.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.27 5878 123 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.27 5878 121 2.1% 2 +[H69-,V70-,H146-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.27 5878 56 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.27 5878 50 0.9% 1 +[H69-,V70-,F157L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.3 5870 4267 72.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.3 5870 170 2.9% 1 +[H69-,V70-,G75A,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.3 5870 96 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.3 5870 70 1.2% 1 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.3 5870 67 1.1% 1 +[L5I,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.36 5813 2624 45.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36 5813 349 6.0% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36 5813 173 3.0% 1 +[I210-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36 5813 105 1.8% 1 +[Q23R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36 5813 98 1.7% 1 +[M1050I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.4 5771 4067 70.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.4 5771 601 10.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.4 5771 137 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.4 5771 58 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.4 5771 42 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] Q.3 5754 3676 63.9% 0 +[H69-,V70-,D178H,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.3 5754 1207 21.0% 1 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.3 5754 149 2.6% 2 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.3 5754 65 1.1% 2 +[H69-,V70-,M177I,D178H,A222V,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.3 5754 30 0.5% 1 +[H69-,V70-,M177I,D178H,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] P.2 5733 3866 67.4% 0 +[E484K,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.2 5733 283 4.9% 1 +[E484K,F565L,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.2 5733 79 1.4% 1 +[L5F,E484K,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.2 5733 46 0.8% 1 +[E484K,T859I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.2 5733 32 0.6% 1 +[E484K,P809S,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.16 5651 3423 60.6% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.16 5651 1259 22.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,V1264M]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16 5651 77 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,D627G,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16 5651 76 1.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.16 5651 41 0.7% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,H625R,N856K,L981F,V1264M]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XBB.1.16.1 5631 3773 67.0% 0 +[E180V,T478R,T547I]-[T478K] (consensus) XBB.1.16.1 5631 109 1.9% 1 +[H146K,E180V,T478R,T547I]-[H146Q,T478K] XBB.1.16.1 5631 65 1.2% 1 +[E180V,T478R,T547I,E554K]-[T478K] XBB.1.16.1 5631 64 1.1% 1 +[E180V,T478R,P521S,T547I]-[T478K] XBB.1.16.1 5631 51 0.9% 1 +[E180V,T478R,T547I]-[K417N,T478K] BA.1.1.13 5585 4744 84.9% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.13 5585 172 3.1% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.13 5585 60 1.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.13 5585 44 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212-,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.13 5585 28 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,K417T,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BF.7.14 5538 4170 75.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14 5538 65 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691F,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14 5538 50 0.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14 5538 33 0.6% 1 +[H69-,V70-,V213G,G339D,S366A,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14 5538 28 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,E1202Q,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] Q.1 5392 4080 75.7% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.1 5392 186 3.4% 1 +[H69-,V70-,A570D,T632S,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.1 5392 100 1.9% 1 +[H69-,V70-,A570D,T716I,T732I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.1 5392 81 1.5% 2 +[H69-,V70-,V367A,E484K,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.1 5392 52 1.0% 1 +[L18F,H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.74 5360 3978 74.2% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.74 5360 224 4.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.74 5360 172 3.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.74 5360 74 1.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.74 5360 56 1.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,A688V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124 5339 1975 37.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.124 5339 1157 21.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124 5339 139 2.6% 2 +[L8V,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124 5339 83 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,A688V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.124 5339 83 1.6% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.10 5326 2772 52.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.10 5326 1179 22.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10 5326 94 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10 5326 92 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10 5326 37 0.7% 1 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.2.10.1 5251 3985 75.9% 0 +[V213G,G339D,Q493R,G798D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.10.1 5251 174 3.3% 2 +[T19L,V159I,V213G,G339D,Q493R,G798D]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.1 5251 99 1.9% 1 +[V213G,G339D,Q493R,G798D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.10.1 5251 95 1.8% 1 +[V213G,G339D,Q493R,Q677H,G798D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.1 5251 58 1.1% 1 +[L5F,V213G,G339D,Q493R,G798D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.7.1 5232 3077 58.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.7.1 5232 661 12.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A688V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.1 5232 635 12.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.1 5232 52 1.0% 2 +[T19R,E156G,F157-,R158-,A263V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.1 5232 50 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.525 5186 3105 59.9% 0 +[Q52R,A67V,H69-,V70-,E484K,Q677H,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.525 5186 188 3.6% 1 +[Q52R,A67V,H69-,V70-,E484K,Q677H,D839Y,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.525 5186 91 1.8% 1 +[Q52R,A67V,H69-,V70-,K150N,E484K,Q677H,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.525 5186 73 1.4% 1 +[A67V,H69-,V70-,E484K,Q677H,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.525 5186 68 1.3% 1 +[Q52R,A67V,H69-,V70-,G181A,E484K,Q677H,F888L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.6 5150 4616 89.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.6 5150 69 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,R1091H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.6 5150 36 0.7% 1 +[T19R,D80Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.6 5150 28 0.5% 1 +[T19R,E156G,F157-,R158-,T274I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.6 5150 26 0.5% 1 +[T19R,E156G,F157-,R158-,L452R,Y660F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.12 5124 4123 80.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.12 5124 98 1.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.12 5124 42 0.8% 1 +[H69-,V70-,V213G,S254F,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.12 5124 40 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N679K] BQ.1.12 5124 21 0.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I584V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.1.3 5066 2943 58.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.3 5066 584 11.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.3 5066 220 4.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.3 5066 89 1.8% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.3 5066 85 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.1.14 5039 3930 78.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.14 5039 123 2.4% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.14 5039 94 1.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.14 5039 63 1.3% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.14 5039 55 1.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] B 5028 4062 80.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B 5028 129 2.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B 5028 37 0.7% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B 5028 22 0.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B 5028 17 0.3% 1 +[S247R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17 5000 3660 73.2% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.17 5000 160 3.2% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,D936Y,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17 5000 95 1.9% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17 5000 66 1.3% 1 +[L18F,T20N,P26S,G75V,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17 5000 61 1.2% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F,E1258D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.24 4993 4057 81.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.24 4993 82 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.24 4993 78 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.24 4993 42 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.24 4993 40 0.8% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.1 4992 2993 60.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3.1 4992 188 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.1 4992 158 3.2% 3 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.3.1 4992 153 3.1% 2 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V,A829T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.1 4992 101 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A829T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.369 4964 1968 39.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.369 4964 608 12.2% 1 +[E780Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.369 4964 310 6.2% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.369 4964 266 5.4% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.369 4964 155 3.1% 1 +[A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.60 4955 3171 64.0% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.60 4955 180 3.6% 1 +[L5F,L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.60 4955 173 3.5% 1 +[L18F,A222V,R1091H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.60 4955 124 2.5% 2 +[L18F,A222V,K558N,V687I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.60 4955 76 1.5% 1 +[L18F,A222V,I1232V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240 4926 2583 52.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.240 4926 615 12.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240 4926 275 5.6% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240 4926 158 3.2% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.240 4926 101 2.1% 1 +[A575S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.6 4851 3339 68.8% 0 +[D253G,F486S]-[G252V,F486P] (consensus) XBB.2.6 4851 279 5.8% 1 +[D253G,F486S]-[G252V,R408S,F486P] XBB.2.6 4851 81 1.7% 1 +[H146K,D253G,F486S]-[H146Q,G252V,F486P] XBB.2.6 4851 70 1.4% 1 +[D253G,F486S]-[Q183E,G252V,F486P] XBB.2.6 4851 51 1.1% 1 +[N148T,D253G,F486S]-[G252V,F486P] B.1.177.86 4768 2791 58.5% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.86 4768 604 12.7% 1 +[L18F,A222V,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.86 4768 211 4.4% 2 +[L18F,A222V,T547I,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.86 4768 146 3.1% 1 +[L18F,A222V,Q779K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.86 4768 119 2.5% 1 +[L18F,A222V,A1070S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.1 4707 3432 72.9% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.1 4707 55 1.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.1 4707 51 1.1% 1 +[K147E,W152R,F157L,N185D,F186L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.1 4707 33 0.7% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q675K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.1 4707 32 0.7% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.39.1.1 4666 3538 75.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.1.1 4666 377 8.1% 1 +[T19R,T95I,E156G,F157-,R158-,G219D,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.1 4666 172 3.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,R765H,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.1 4666 113 2.4% 1 +[T19R,R21T,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.1 4666 85 1.8% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,N481K,P681R,R765H,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.14 4633 3400 73.4% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.14 4633 95 2.1% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,D1118Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.14 4633 59 1.3% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,I742V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.14 4633 53 1.1% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.14 4633 47 1.0% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12 4619 3802 82.3% 0 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.12 4619 74 1.6% 1 +[G75V,V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12 4619 68 1.5% 1 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.12 4619 58 1.3% 1 +[L5F,V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12 4619 34 0.7% 1 +[V213G,G339D,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BR.2.1 4612 3714 80.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BR.2.1 4612 34 0.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I,N556K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2.1 4612 33 0.7% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2.1 4612 31 0.7% 1 +[K147E,W152R,F157L,I210V,L212S,V213G,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2.1 4612 26 0.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I,Q1208H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FU.1 4576 3418 74.7% 0 +[E180V,T478R,T547I]-[T478K] (consensus) FU.1 4576 127 2.8% 1 +[E180V,T478R,T547I,N703Y]-[T478K] FU.1 4576 55 1.2% 1 +[H146K,E180V,T478R,T547I]-[H146Q,T478K] FU.1 4576 39 0.9% 1 +[E180V,T478R,T547I]-[Y144-,T478K] FU.1 4576 30 0.7% 1 +[E180V,T478R,T547I,K1266R]-[T478K] BQ.1.14 4545 3298 72.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.14 4545 139 3.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.14 4545 78 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E1258D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.14 4545 49 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.14 4545 42 0.9% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.1.222 4527 1872 41.4% 0 +[T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.222 4527 225 5.0% 2 +[T732A,A1078S,V1228I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.222 4527 166 3.7% 1 +[G257S,T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.222 4527 160 3.5% 1 +[T732A,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.222 4527 140 3.1% 2 +[T732A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.34.1 4483 1846 41.2% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.34.1 4483 594 13.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,V1133I,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1 4483 488 10.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1 4483 218 4.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,V1264A,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1 4483 86 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,P174S,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.1 4453 3604 80.9% 0 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.29.1 4453 151 3.4% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.1 4453 93 2.1% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,T553I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.1 4453 86 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.1 4453 47 1.1% 1 +[T19R,T95I,E156G,F157-,R158-,Q173H,L176F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.8 4406 3424 77.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.8 4406 100 2.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.8 4406 58 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.8 4406 54 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.8 4406 35 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EG.1 4388 2464 56.2% 0 +[Q613H] (consensus) EG.1 4388 311 7.1% 1 +[Q613H,G1124V] EG.1 4388 69 1.6% 1 +[H146K,Q613H]-[H146Q] EG.1 4388 60 1.4% 1 +[L452R,Q613H] EG.1 4388 44 1.0% 2 +[T29I,Q613H,A706V] B.1.177.81 4329 3075 71.0% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.81 4329 112 2.6% 1 +[A222V,T240I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.81 4329 111 2.6% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.81 4329 78 1.8% 1 +[A222V,D839Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.81 4329 52 1.2% 1 +[A222V,V227L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.4 4320 3334 77.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.4 4320 70 1.6% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4 4320 65 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T827I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.4 4320 48 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.4 4320 30 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1263L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DY.2 4305 3315 77.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DY.2 4305 40 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1163V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.2 4305 35 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.2 4305 33 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.2 4305 20 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.9.2 4270 2100 49.2% 0 (consensus) XBB.1.9.2 4270 183 4.3% 2 +[Q52H,F456L] XBB.1.9.2 4270 101 2.4% 1 +[H146K]-[H146Q] XBB.1.9.2 4270 80 1.9% 1 +[I794T] XBB.1.9.2 4270 71 1.7% 2 +[V70A,C1247S] BE.1.1.2 4251 3514 82.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.1.2 4251 93 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.1.2 4251 50 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1.2 4251 36 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BE.1.1.2 4251 35 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BQ.1.8 4211 3117 74.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.8 4211 80 1.9% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.8 4211 68 1.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.8 4211 56 1.3% 1 +[H69-,V70-,V213G,D215Y,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.8 4211 53 1.3% 2 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,S940F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.1.37 4210 2700 64.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.37 4210 324 7.7% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.37 4210 252 6.0% 4 +[L5F,A222V,D574Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.37 4210 216 5.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.37 4210 58 1.4% 1 +[P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.7 4196 3271 78.0% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.7 4196 215 5.1% 1 +[L18F,A222V,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.7 4196 151 3.6% 1 +[L18F,N185S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.7 4196 103 2.5% 1 +[L18F,A222V,S256L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.7 4196 60 1.4% 1 +[L18F,A67S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.5 4182 2093 50.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.5 4182 589 14.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.5 4182 149 3.6% 1 +[H69-,V70-,S98F,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.5 4182 120 2.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.5 4182 73 1.7% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] FL.4 4169 2712 65.1% 0 (consensus) FL.4 4169 85 2.0% 1 +[H146K]-[H146Q] FL.4 4169 61 1.5% 1 +[R1014K] FL.4 4169 50 1.2% 1 -[K417N] FL.4 4169 35 0.8% 2 -[R408S,S477N] AY.4.2.3 4166 1671 40.1% 0 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2.3 4166 1006 24.1% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,L1049I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.3 4166 256 6.1% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.3 4166 161 3.9% 2 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,D950N,L1049I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.3 4166 42 1.0% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,L452R,P681R,P812L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.5 4163 2539 61.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.5 4163 684 16.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.5 4163 51 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A845S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.5 4163 43 1.0% 2 +[V6I,H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.5 4163 38 0.9% 5 +[H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.16.11 4104 2722 66.3% 0 +[E180V,T478R,P521T]-[T478K] (consensus) XBB.1.16.11 4104 127 3.1% 1 +[G72E,E180V,T478R,P521T]-[T478K] XBB.1.16.11 4104 78 1.9% 1 +[E180V,S256L,T478R,P521T]-[T478K] XBB.1.16.11 4104 53 1.3% 1 +[R78K,E180V,T478R,P521T]-[T478K] XBB.1.16.11 4104 50 1.2% 1 +[E180V,F186L,T478R,P521T]-[T478K] BQ.1.11 4072 2567 63.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.11 4072 322 7.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.11 4072 288 7.1% 1 +[H69-,V70-,W152L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.11 4072 117 2.9% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.11 4072 46 1.1% 1 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBB.2.3 4049 1822 45.0% 0 +[D253G,P521S]-[G252V] (consensus) XBB.2.3 4049 155 3.8% 1 +[G184V,D253G,P521S]-[G252V] XBB.2.3 4049 120 3.0% 1 +[I210-,D253G,P521S]-[G252V] XBB.2.3 4049 97 2.4% 1 +[D253G,S256T,P521S]-[G252V] XBB.2.3 4049 59 1.5% 1 +[H146K,D253G,P521S]-[H146Q,G252V] BQ.1.1.5 4034 2559 63.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.5 4034 390 9.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.5 4034 57 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.5 4034 34 0.8% 1 +[H69-,V70-,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.5 4034 32 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BF.7.15 4015 3291 82.0% 0 +[H69-,V70-,V213G,G257D,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.15 4015 99 2.5% 1 +[L8F,H69-,V70-,V213G,G257D,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.15 4015 59 1.5% 1 +[H69-,V70-,V213G,G257D,G339D,L452R,F486V,L752F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.15 4015 48 1.2% 1 +[H69-,V70-,V213G,G257D,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.15 4015 43 1.1% 1 +[L5F,H69-,V70-,V213G,G257D,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.46.4 3978 2310 58.1% 0 +[T19R,E156G,F157-,R158-,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.4 3978 597 15.0% 1 +[T19R,E156G,F157-,R158-,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.4 3978 299 7.5% 1 +[T19R,E156G,F157-,R158-,A222S,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.4 3978 116 2.9% 2 +[T19R,E156G,F157-,R158-,A222S,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.4 3978 26 0.7% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,E661D,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.23 3972 3013 75.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.23 3972 49 1.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.23 3972 35 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A1078S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.23 3972 34 0.9% 1 +[H69-,V70-,V213G,Q271K,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.23 3972 25 0.6% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBB.1.5.13 3908 2775 71.0% 0 (consensus) XBB.1.5.13 3908 55 1.4% 1 -[K417N] XBB.1.5.13 3908 50 1.3% 1 +[H146K]-[H146Q] XBB.1.5.13 3908 34 0.9% 1 +[P1162L] XBB.1.5.13 3908 23 0.6% 2 -[R408S,S477N] B.1.177.4 3905 3376 86.5% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.4 3905 77 2.0% 1 +[A222V,D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.4 3905 37 0.9% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.4 3905 18 0.5% 1 +[A222V,P1263T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.4 3905 14 0.4% 1 +[S12F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.2 3848 3335 86.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AD.2 3848 93 2.4% 1 +[S71P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.2 3848 44 1.1% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.2 3848 21 0.5% 1 +[L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AD.2 3848 21 0.5% 1 +[A626V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.7 3833 2318 60.5% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] (consensus) P.1.7 3833 132 3.4% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7 3833 70 1.8% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E780A,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7 3833 61 1.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,Q613H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7 3833 60 1.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E654Q,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] BA.1.21 3813 3202 84.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.21 3813 117 3.1% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.21 3813 39 1.0% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214GAR,D215N,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.21 3813 30 0.8% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.21 3813 29 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] B.1.1.28 3802 2029 53.4% 0 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.28 3802 156 4.1% 2 +[M153T,S689I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.28 3802 64 1.7% 3 +[M153T,N658T,S689I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.28 3802 58 1.5% 2 +[A222V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.28 3802 46 1.2% 6 +[G142V,N164K,Q173K,L452R,S704L,I720V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.2 3789 3040 80.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.2 3789 103 2.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.2 3789 40 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.2 3789 39 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1164I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.2 3789 24 0.6% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.25 3744 2624 70.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.25 3744 155 4.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.25 3744 132 3.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.25 3744 93 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.25 3744 51 1.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.34 3742 2512 67.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.34 3742 126 3.4% 1 +[H69-,V70-,V213G,D215E,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.34 3742 118 3.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.34 3742 53 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.34 3742 52 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.28 3741 2481 66.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.28 3741 113 3.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.28 3741 77 2.1% 1 +[H69-,V70-,V213G,G339D,S359N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.28 3741 55 1.5% 1 +[H69-,V70-,G184S,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.28 3741 47 1.3% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.8 3728 2915 78.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.8 3728 143 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L,Q1201H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.8 3728 76 2.0% 1 +[H69-,V70-,W152R,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.8 3728 34 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.8 3728 34 0.9% 1 +[R21T,H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13 3724 2234 60.0% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.13 3724 898 24.1% 1 +[V213G,G339D,L452M,Q493R,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13 3724 70 1.9% 2 +[V213G,S255F,G339D,L452M,Q493R,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13 3724 43 1.2% 1 +[L5F,V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13 3724 35 0.9% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.122.5 3682 1779 48.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.5 3682 1034 28.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.5 3682 124 3.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.5 3682 117 3.2% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.5 3682 85 2.3% 2 +[T19R,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BD.1 3681 3175 86.3% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BD.1 3681 47 1.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BD.1 3681 42 1.1% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BD.1 3681 39 1.1% 1 +[A67V,H69-,V70-,T95I,I105L,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BD.1 3681 32 0.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,A701V,N856K,L981F,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.4.8 3665 3027 82.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.8 3665 94 2.6% 1 +[T19R,T95I,E156G,F157-,R158-,G181R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.8 3665 34 0.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,A647S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.8 3665 32 0.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,T961M]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.8 3665 31 0.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.22 3661 2781 76.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.22 3661 68 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.22 3661 60 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.22 3661 51 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.22 3661 45 1.2% 1 +[H69-,V70-,V213G,T250A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.112 3602 1358 37.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.112 3602 583 16.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112 3602 134 3.7% 1 +[T19R,T95I,E156G,F157-,R158-,S254F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112 3602 60 1.7% 2 +[T19R,T95I,E156G,F157-,R158-,S254F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.112 3602 51 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,E1207D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.26 3600 2406 66.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.26 3600 128 3.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.26 3600 122 3.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.26 3600 55 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.26 3600 43 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.43.8 3572 1979 55.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.8 3572 415 11.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.8 3572 166 4.6% 1 +[L18F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.8 3572 132 3.7% 1 +[T19R,E156G,F157-,R158-,R214L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.8 3572 42 1.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,L822I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DY.4 3549 2779 78.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DY.4 3549 75 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] DY.4 3549 30 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.4 3549 29 0.8% 1 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.4 3549 19 0.5% 1 +[H69-,V70-,V213G,T307I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] A.1 3545 3113 87.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.1 3545 54 1.5% 1 +[V483A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.1 3545 29 0.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.1 3545 25 0.7% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.1 3545 17 0.5% 1 +[A623V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.3 3542 2303 65.0% 0 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.25.3 3542 664 18.7% 1 +[T19R,E156G,F157-,R158-,L176F,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.3 3542 146 4.1% 1 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.3 3542 45 1.3% 1 +[L5F,T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.25.3 3542 24 0.7% 1 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,S704L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.13 3513 1969 56.0% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.13 3513 415 11.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.13 3513 306 8.7% 1 +[T19R,E156G,F157-,R158-,I210-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.13 3513 81 2.3% 2 +[T19R,E156G,F157-,R158-,I210-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.13 3513 48 1.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,S940F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.114 3508 1959 55.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.114 3508 625 17.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.114 3508 46 1.3% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.114 3508 37 1.1% 2 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.114 3508 30 0.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,S640F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1 3454 2234 64.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1 3454 169 4.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T961M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1 3454 39 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1 3454 38 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S929T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1 3454 27 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] AY.93 3437 2729 79.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.93 3437 62 1.8% 1 +[T19R,E156G,F157-,R158-,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.93 3437 60 1.7% 1 +[T19R,E156G,F157-,R158-,L452R,T547I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.93 3437 36 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,I818V,D950N,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.93 3437 29 0.8% 1 +[T19R,E156G,F157-,R158-,L452R,A623S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595 3366 2261 67.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.595 3366 117 3.5% 1 +[A1087G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595 3366 109 3.2% 1 +[D178G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595 3366 53 1.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.595 3366 50 1.5% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.1 3343 1943 58.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.1 3343 187 5.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.1 3343 67 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.1 3343 55 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.1 3343 51 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.497 3316 2697 81.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.497 3316 77 2.3% 2 +[Q52H,N556K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.497 3316 50 1.5% 1 +[I1169F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.497 3316 50 1.5% 1 +[A684T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.497 3316 26 0.8% 1 +[T20N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.6.5 3303 2665 80.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.6.5 3303 38 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.6.5 3303 33 1.0% 1 +[W64L,H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.5 3303 29 0.9% 1 +[H69-,V70-,V213G,T250I,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.5 3303 25 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EG.5.1.4 3301 2241 67.9% 0 +[Q52H,F456L] (consensus) EG.5.1.4 3301 174 5.3% 1 +[Q52H,L455F,F456L] EG.5.1.4 3301 102 3.1% 1 +[Q52H,H146K,F456L]-[H146Q] EG.5.1.4 3301 41 1.2% 1 +[Q52H,F456L,V483I] EG.5.1.4 3301 40 1.2% 1 +[Q52H,F456L,E654K] AY.85 3299 998 30.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.85 3299 798 24.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.85 3299 135 4.1% 2 +[T19R,T95I,E156G,F157-,R158-,F306L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.85 3299 99 3.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,S698A,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.85 3299 41 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,G219D,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GJ.1.2 3278 2081 63.5% 0 +[K182N,D253G,P521S]-[G252V] (consensus) GJ.1.2 3278 107 3.3% 1 +[H146K,K182N,D253G,P521S]-[H146Q,G252V] GJ.1.2 3278 58 1.8% 1 +[K182N,D253G,T478R,P521S]-[G252V,T478K] GJ.1.2 3278 46 1.4% 1 +[K150I,K182N,D253G,P521S]-[G252V] GJ.1.2 3278 30 0.9% 1 +[K182N,D253G,P521S]-[G252V,K417N] BA.2.75.2 3258 2096 64.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BA.2.75.2 3258 45 1.4% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.2 3258 36 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.2 3258 35 1.1% 1 +[K147E,W152R,F157L,I210V,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F486P,F490S] BA.2.75.2 3258 32 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,L1186I,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.38 3240 1705 52.6% 0 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.38 3240 215 6.6% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.38 3240 121 3.7% 1 +[V213G,G339D,K417T,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38 3240 101 3.1% 4 +[V213G,G339D,K417T,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.38 3240 99 3.1% 1 +[V213G,G339D,K417T,K444N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] AY.7 3215 2528 78.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.7 3215 91 2.8% 1 +[T19R,E156G,F157-,R158-,Y265C,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7 3215 78 2.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,T747I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7 3215 57 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7 3215 45 1.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1224S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] BF.4 3207 2460 76.7% 0 +[H69-,V70-,V213G,T259A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.4 3207 70 2.2% 1 +[H69-,V70-,V213G,T259A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.4 3207 61 1.9% 2 +[T19L,H69-,V70-,V213G,T259A,G339D,L452R,F486V,D1153N]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.4 3207 42 1.3% 1 +[H69-,V70-,V213G,T259A,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.4 3207 37 1.2% 1 +[H69-,V70-,V213G,T259A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.20 3202 2002 62.5% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) BA.2.3.20 3202 44 1.4% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478E,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] BA.2.3.20 3202 38 1.2% 1 +[M153T,N164K,M177I,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BA.2.3.20 3202 36 1.1% 1 +[M153T,N164K,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BA.2.3.20 3202 33 1.0% 1 +[M153T,N164K,V213G,H245N,Y248H,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BA.2.65 3201 2298 71.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.65 3201 213 6.7% 1 +[V213G,G339N,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.65 3201 71 2.2% 1 +[V213G,G339D,Q493R,E1195G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.65 3201 60 1.9% 1 +[V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.65 3201 46 1.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BQ.1.3.2 3184 2337 73.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.3.2 3184 121 3.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,V1133A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.2 3184 52 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.2 3184 42 1.3% 1 +[H69-,V70-,W152R,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.2 3184 20 0.6% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,A701V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] P.1.15 3178 2208 69.5% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.15 3178 124 3.9% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,G1085E,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.15 3178 35 1.1% 1 +[L18F,T20N,P26S,D138Y,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.15 3178 28 0.9% 1 +[L5F,L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.15 3178 23 0.7% 2 +[L18F,T20N,P25S,P26S,D138Y,R190S,K417T,E484K,T1027I,G1085E,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.33 3173 2128 67.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.33 3173 57 1.8% 1 +[Q23K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.33 3173 32 1.0% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.33 3173 23 0.7% 1 +[V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.33 3173 22 0.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.101 3107 1175 37.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.101 3107 758 24.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.101 3107 160 5.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.101 3107 79 2.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.101 3107 38 1.2% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.7 3089 2128 68.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.7 3089 197 6.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.7 3089 43 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,V1230M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.7 3089 25 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T1077A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.7 3089 22 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,F643L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.7 3079 2176 70.7% 0 (consensus) XBB.1.5.7 3079 50 1.6% 1 -[K417N] XBB.1.5.7 3079 46 1.5% 1 +[H146K]-[H146Q] XBB.1.5.7 3079 31 1.0% 2 -[R408S,S477N] XBB.1.5.7 3079 29 0.9% 2 +[H146K,D936H]-[H146Q] BA.1.1.12 3076 2698 87.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.12 3076 59 1.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,S704L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.12 3076 52 1.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,T299I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.12 3076 34 1.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,P272L,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.12 3076 21 0.7% 1 +[L54F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.5.1.6 3058 1892 61.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.6 3058 178 5.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.6 3058 160 5.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.6 3058 120 3.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.6 3058 56 1.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.15 3040 1952 64.2% 0 (consensus) XBB.1.5.15 3040 114 3.8% 2 +[N185D,F456L] XBB.1.5.15 3040 61 2.0% 1 +[H146K]-[H146Q] XBB.1.5.15 3040 46 1.5% 1 -[K417N] XBB.1.5.15 3040 39 1.3% 1 +[G181V] BA.5.2.2 2996 2083 69.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.2 2996 184 6.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1219C]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.2 2996 114 3.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.2 2996 35 1.2% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.2 2996 24 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] GK.1.1 2972 1946 65.5% 0 +[L455F,F456L,T573I,S704L] (consensus) GK.1.1 2972 49 1.6% 1 +[L5F,L455F,F456L,T573I,S704L] GK.1.1 2972 43 1.4% 1 +[H146K,L455F,F456L,T573I,S704L]-[H146Q] GK.1.1 2972 33 1.1% 1 +[L455F,F456L,T573I,S704L,G946V] GK.1.1 2972 32 1.1% 1 +[A262P,L455F,F456L,T573I,S704L] B.1.311 2951 1133 38.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.311 2951 475 16.1% 1 +[G72R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.311 2951 309 10.5% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.311 2951 202 6.8% 1 +[S12F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.311 2951 119 4.0% 2 +[D88H,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.16 2944 2624 89.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.16 2944 17 0.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.16 2944 16 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.16 2944 16 0.5% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.16 2944 14 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,L452M,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.70 2888 1800 62.3% 0 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.70 2888 602 20.8% 1 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.70 2888 25 0.9% 2 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.70 2888 22 0.8% 1 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R,D950N,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.70 2888 22 0.8% 2 +[T19R,R21T,E156G,F157-,R158-,A222V,L452R,P681R,D950N,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HF.1 2875 2099 73.0% 0 +[E180V,K304N,T478R]-[T478K] (consensus) HF.1 2875 62 2.2% 1 +[H146K,E180V,K304N,T478R]-[H146Q,T478K] HF.1 2875 36 1.3% 1 +[G75V,E180V,K304N,T478R]-[T478K] HF.1 2875 34 1.2% 2 +[E180V,K304N,T478R,D1084N,H1101Y]-[T478K] HF.1 2875 22 0.8% 1 +[L5F,E180V,K304N,T478R]-[T478K] P.1.10 2855 2143 75.1% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.10 2855 225 7.9% 1 +[L18F,T20N,P26S,D138Y,Q183H,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10 2855 41 1.4% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,N606K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10 2855 32 1.1% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.10 2855 24 0.8% 1 +[L18F,T20N,P26S,D138Y,R190S,T323I,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.70 2840 1230 43.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.70 2840 698 24.6% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.70 2840 71 2.5% 2 +[H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.70 2840 68 2.4% 1 +[A1078V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.70 2840 45 1.6% 2 +[L5F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.30 2838 1018 35.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.30 2838 838 29.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.30 2838 178 6.3% 4 +[T19R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.30 2838 34 1.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.30 2838 28 1.0% 3 +[T19R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.48 2817 2254 80.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.48 2817 32 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.48 2817 15 0.5% 1 +[H69-,V70-,V213G,L277F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.48 2817 10 0.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.48 2817 9 0.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BQ.1.18 2805 2127 75.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.18 2805 46 1.6% 1 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.18 2805 45 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.18 2805 40 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S939F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.18 2805 26 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] B.1.177.57 2805 2060 73.4% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.57 2805 297 10.6% 2 +[P26S,A222V,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.57 2805 67 2.4% 1 +[A222V,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.57 2805 22 0.8% 1 +[A222V,A575S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.57 2805 20 0.7% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.27 2799 1670 59.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.27 2799 290 10.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.27 2799 46 1.6% 1 +[H69-,V70-,K147I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.27 2799 39 1.4% 1 +[H69-,V70-,K97T,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.27 2799 36 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D936G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.575 2798 1998 71.4% 0 +[S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.575 2798 155 5.5% 1 +[S494P,T716I,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575 2798 49 1.8% 1 +[W152R,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575 2798 40 1.4% 2 +[S494P,T716I,S735L,A893S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.575 2798 36 1.3% 1 +[L5F,S494P,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.120.1 2796 1507 53.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.120.1 2796 477 17.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.1 2796 78 2.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.1 2796 39 1.4% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.1 2796 35 1.3% 1 +[T19R,L54F,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.13.1 2768 2423 87.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.13.1 2768 64 2.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,Q1201K]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.13.1 2768 49 1.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.13.1 2768 28 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.13.1 2768 8 0.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,S1021F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.5.5.1 2757 2209 80.1% 0 +[H69-,V70-,T76I,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.5.1 2757 52 1.9% 1 +[H69-,V70-,T76I,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.1 2757 33 1.2% 1 +[L5F,H69-,V70-,T76I,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.1 2757 31 1.1% 1 +[H69-,V70-,T76I,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.5.1 2757 22 0.8% 1 +[H69-,V70-,T76I,V213G,S255F,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.318 2749 1856 67.5% 0 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.318 2749 111 4.0% 1 +[T95I,E484K,D796H,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.318 2749 60 2.2% 1 +[T95I,E484K,D796H,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.318 2749 40 1.5% 1 +[T95I,E484K,N501T,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.318 2749 32 1.2% 2 +[T95I,E484K,D796H,A1078S,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BE.9 2745 2107 76.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BE.9 2745 57 2.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.9 2745 43 1.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.9 2745 40 1.5% 1 +[H69-,V70-,F157S,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.9 2745 31 1.1% 1 +[H69-,V70-,V213G,S255F,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.1.69 2724 1830 67.2% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.69 2724 211 7.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.69 2724 46 1.7% 1 +[H69-,V70-,V213G,G252D,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.69 2724 33 1.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.69 2724 26 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.9.3 2720 2100 77.2% 0 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.3 2720 153 5.6% 1 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.9.3 2720 47 1.7% 1 +[W64R,M153T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.3 2720 24 0.9% 1 +[W64R,V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.3 2720 18 0.7% 2 +[W64R,V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] EG.6.1 2708 1801 66.5% 0 +[F456L] (consensus) EG.6.1 2708 80 3.0% 1 +[F456L]-[R408S] EG.6.1 2708 57 2.1% 1 +[H146K,F456L]-[H146Q] EG.6.1 2708 51 1.9% 1 +[F456L,C1236F] EG.6.1 2708 29 1.1% 1 +[F456L,V705I] BA.2.76 2696 1955 72.5% 0 +[V213G,Y248N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.76 2696 135 5.0% 1 +[V213G,Y248N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.76 2696 52 1.9% 4 +[V213G,Y248N,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.76 2696 38 1.4% 1 +[L5F,V213G,Y248N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.76 2696 24 0.9% 1 +[V213G,Y248N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.110 2687 1533 57.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.110 2687 593 22.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.110 2687 44 1.6% 1 +[T19R,T95I,K97R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.110 2687 36 1.3% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.110 2687 31 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,A623V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JD.1.1 2679 1860 69.4% 0 +[L455F,F456L,A475V] (consensus) JD.1.1 2679 39 1.5% 1 +[H146K,L455F,F456L,A475V]-[H146Q] JD.1.1 2679 26 1.0% 1 +[L455F,F456L,A475V]-[T19I] JD.1.1 2679 24 0.9% 1 +[L455F,F456L,A475V,T478R]-[T478K] JD.1.1 2679 24 0.9% 1 +[L455F,F456L,A475V,S1252P] BA.5.2.35 2671 1960 73.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.35 2671 57 2.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.35 2671 34 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.35 2671 30 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,N460K,F486P,F490S] BA.5.2.35 2671 25 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.7 2666 2213 83.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.7 2666 98 3.7% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.7 2666 76 2.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.7 2666 24 0.9% 2 +[L5F,V213G,G339D,Q493R,I1130V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.7 2666 16 0.6% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.39.1.4 2601 2272 87.4% 0 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.1.4 2601 24 0.9% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.4 2601 22 0.8% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,A222S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.4 2601 19 0.7% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,N856K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.4 2601 19 0.7% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D936Y,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116.1 2595 1460 56.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.116.1 2595 302 11.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116.1 2595 81 3.1% 1 +[S12F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116.1 2595 65 2.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116.1 2595 51 2.0% 1 +[T19R,T95I,E156G,F157-,R158-,F306L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.3 2592 737 28.4% 0 +[T19R,P26S,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.3 2592 493 19.0% 1 +[T19R,P26S,L54F,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.3 2592 359 13.9% 3 +[T19R,P26S,L54F,T95I,E156G,F157-,R158-,A262S,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.3 2592 146 5.6% 2 +[T19R,P26S,L54F,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.3 2592 99 3.8% 1 +[T19R,P26S,T95I,E156G,F157-,R158-,M177I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.13 2581 1298 50.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.13 2581 650 25.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13 2581 68 2.6% 1 +[H69-,V70-,G184S,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13 2581 52 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T618K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13 2581 37 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L1244F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] ED.1 2560 2229 87.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) ED.1 2560 43 1.7% 1 +[H69-,V70-,T208M,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.1 2560 17 0.7% 1 +[H69-,V70-,V213G,L242F,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.1 2560 13 0.5% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.1 2560 12 0.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.4.1.1 2558 1612 63.0% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,I670V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.1 2558 429 16.8% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.1 2558 45 1.8% 4 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.1 2558 43 1.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,I670V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.1 2558 37 1.4% 1 +[V3G,H69-,V70-,G181V,V213G,G339D,L452R,F486V,I670V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.1 2552 1780 69.7% 0 +[T573I] (consensus) XBB.1.5.1 2552 41 1.6% 1 XBB.1.5.1 2552 35 1.4% 1 +[T573I]-[K417N] XBB.1.5.1 2552 34 1.3% 1 +[H146K,T573I]-[H146Q] XBB.1.5.1 2552 33 1.3% 1 +[T478R,T573I]-[T478K] AY.121.1 2548 1457 57.2% 0 +[T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.121.1 2548 168 6.6% 1 +[T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121.1 2548 118 4.6% 1 +[V6F,T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121.1 2548 104 4.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.121.1 2548 42 1.6% 2 +[T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N,N1158D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.13 2534 1912 75.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.13 2534 49 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.13 2534 39 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S1147L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.13 2534 29 1.1% 1 +[H69-,V70-,V213G,T250I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.13 2534 27 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T791I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.6 2531 1759 69.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.6 2531 40 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.6 2531 36 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.6 2531 34 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.6 2531 26 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] EG.5.1.6 2524 1813 71.8% 0 +[Q52H,F157L,F456L] (consensus) EG.5.1.6 2524 84 3.3% 1 +[Q52H,F157L,N211I,F456L] EG.5.1.6 2524 53 2.1% 1 +[Q52H,F157L,L455F,F456L] EG.5.1.6 2524 30 1.2% 1 +[L5F,Q52H,F157L,F456L] EG.5.1.6 2524 29 1.1% 1 +[Q52H,H146K,F157L,F456L]-[H146Q] DV.6 2486 1840 74.0% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.6 2486 77 3.1% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,N764K] DV.6 2486 32 1.3% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,I1216V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.6 2486 29 1.2% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,S673T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.6 2486 26 1.0% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S,T678I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.5.3 2483 1329 53.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3 2483 258 10.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3 2483 204 8.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S1170F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3 2483 111 4.5% 1 +[H69-,V70-,V213G,G261C,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3 2483 76 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.39.1.2 2481 1363 54.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.1.2 2481 472 19.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.2 2481 69 2.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q675H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.2 2481 57 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.1.2 2481 40 1.6% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,A522V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.434 2475 1294 52.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.434 2475 555 22.4% 1 +[D1168G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.434 2475 61 2.5% 1 +[D1084G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.434 2475 46 1.9% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.434 2475 33 1.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.2.1 2474 1454 58.8% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.2.2.1 2474 887 35.9% 29 +[V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2.1 2474 40 1.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.2.2.1 2474 22 0.9% 25 +[V213G,G339D,Q493R,I1221T]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.2.1 2474 11 0.4% 30 +[G75A,V213G,G339D,Q493R,I1221T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.107 2453 1375 56.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.107 2453 288 11.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.107 2453 57 2.3% 1 +[T19R,T95I,V143F,E156G,F157-,R158-,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.107 2453 57 2.3% 1 +[T19R,T95I,E156G,F157-,R158-,E180D,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.107 2453 50 2.0% 6 +[L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.49 2446 1406 57.5% 0 (consensus) XBB.1.5.49 2446 102 4.2% 1 +[T478R]-[T478K] XBB.1.5.49 2446 68 2.8% 1 -[K417N] XBB.1.5.49 2446 53 2.2% 1 +[H146K]-[H146Q] XBB.1.5.49 2446 39 1.6% 1 +[T588I] BA.2.3.11 2436 2110 86.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.11 2436 31 1.3% 1 +[V213G,G339D,Q493R,A570V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.11 2436 20 0.8% 1 +[V90I,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.11 2436 19 0.8% 1 +[V213G,G339D,Q493R,V622A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.11 2436 15 0.6% 1 +[V213G,G339D,Q493R,K1191N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.2.3 2432 1686 69.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.2.3 2432 138 5.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2.3 2432 126 5.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,E484V,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] BQ.1.2.3 2432 70 2.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2.3 2432 27 1.1% 1 +[H69-,V70-,L118F,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.1.14.1 2410 1674 69.5% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.14.1 2410 167 6.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] BA.1.14.1 2410 53 2.2% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.14.1 2410 51 2.1% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.14.1 2410 36 1.5% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BN.1.3.1 2392 1784 74.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.1 2392 61 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.3.1 2392 20 0.8% 1 +[K147E,W152R,F157L,G181A,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.1 2392 19 0.8% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.1 2392 17 0.7% 1 +[K147E,W152R,F157L,Q183H,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] A 2390 1762 73.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A 2390 82 3.4% 3 +[A222V,D253Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A 2390 53 2.2% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A 2390 38 1.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A 2390 21 0.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GE.1 2384 1343 56.3% 0 +[N185I,F186-,D253G,T478R,P521S]-[G252V,T478K] (consensus) GE.1 2384 61 2.6% 1 +[M153I,N185I,F186-,D253G,T478R,P521S]-[G252V,T478K] GE.1 2384 41 1.7% 1 +[H146K,N185I,F186-,D253G,T478R,P521S]-[H146Q,G252V,T478K] GE.1 2384 37 1.6% 1 +[E96G,N185I,F186-,D253G,T478R,P521S]-[G252V,T478K] GE.1 2384 32 1.3% 1 +[L118I,N185I,F186-,D253G,T478R,P521S]-[G252V,T478K] AY.29.2 2384 2149 90.1% 0 +[T19R,T95I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.29.2 2384 45 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,V308L,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.2 2384 12 0.5% 1 +[T19R,T95I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.2 2384 10 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N,Q954K]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.29.2 2384 8 0.3% 2 +[T19R,T95I,E156G,F157-,R158-,S254F,Q414R,L452R,P681R,D950N,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.2 2374 1356 57.1% 0 +[N439K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.466.2 2374 245 10.3% 1 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.2 2374 94 4.0% 1 +[W152R,N439K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.2 2374 34 1.4% 1 +[L5F,N439K,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466.2 2374 27 1.1% 1 +[N439K,P681R,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.4 2373 890 37.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5.4 2373 395 16.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.4 2373 292 12.3% 1 +[T19R,D80Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.4 2373 177 7.5% 2 +[T19R,D80Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.4 2373 30 1.3% 3 +[T19R,D80Y,E156G,F157-,R158-,S162I,H245Y,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.15 2371 1533 64.7% 0 +[F486S]-[F486P] (consensus) XBB.1.15 2371 176 7.4% 1 +[F486S]-[K417N,F486P] XBB.1.15 2371 65 2.7% 1 +[F486S,V1122L]-[F486P] XBB.1.15 2371 53 2.2% 1 +[F486S]-[G252V,F486P] XBB.1.15 2371 41 1.7% 1 +[H146K,F486S]-[H146Q,F486P] BN.1.5 2367 1915 80.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.5 2367 19 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.5 2367 12 0.5% 1 +[K147E,W152R,F157L,I210V,V213G,R214H,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.5 2367 11 0.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,P681R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,P681H] BN.1.5 2367 10 0.4% 2 +[K147E,W152R,F157L,I210V,V213G,K356T]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.1.1 2352 1376 58.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.1 2352 208 8.8% 1 +[H146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.1 2352 61 2.6% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.1 2352 36 1.5% 2 +[I818V,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.1 2352 36 1.5% 1 +[A783S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24 2349 1416 60.3% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.24 2349 315 13.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24 2349 66 2.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,T859I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24 2349 63 2.7% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.24 2349 43 1.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.311 2346 1951 83.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.311 2346 104 4.4% 1 +[S477I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.311 2346 21 0.9% 1 +[Q957L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.311 2346 21 0.9% 1 +[N125S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.311 2346 11 0.5% 1 +[H245R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.176 2307 1761 76.3% 0 +[T20I,R357K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.176 2307 281 12.2% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.176 2307 19 0.8% 1 +[L5F,T20I,R357K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.176 2307 18 0.8% 1 +[T20I,R357K,V1264M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.176 2307 17 0.7% 1 +[T20I,R357K,V433I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.63 2301 1955 85.0% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.63 2301 74 3.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,K814R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.63 2301 27 1.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.63 2301 24 1.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,S704L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.63 2301 19 0.8% 1 +[T19R,E156G,F157-,R158-,A222V,P337L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.11 2293 1716 74.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.11 2293 167 7.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1016S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.11 2293 41 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.11 2293 37 1.6% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,A1016S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.11 2293 22 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H625R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.59 2279 1145 50.2% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.59 2279 360 15.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.59 2279 69 3.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.59 2279 22 1.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,G932V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.59 2279 15 0.7% 7 +[T19R,P85T,V90D,Y91D,F92S,S94T,E156G,F157-,R158-,A222V,L452R,P681R,D950N,E1182Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DV.7.1 2274 1530 67.3% 0 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.7.1 2274 41 1.8% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I,D1184Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1 2274 40 1.8% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] DV.7.1 2274 36 1.6% 1 +[V90I,K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.7.1 2274 36 1.6% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,T240I,G257S,K444T,L452R,L455F,F456L,F486S,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.1 2255 1483 65.8% 0 +[T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.1 2255 141 6.3% 1 +[T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.1 2255 76 3.4% 1 +[V16A,T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.1 2255 40 1.8% 2 +[T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.1 2255 30 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,W258L,L452R,P681R,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XE 2239 2039 91.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XE 2239 57 2.5% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XE 2239 17 0.8% 1 +[V213G,H245N,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XE 2239 17 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XE 2239 6 0.3% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.4.9 2238 1352 60.4% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.9 2238 312 13.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.9 2238 57 2.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.9 2238 54 2.4% 3 +[T19R,T95I,E156G,F157-,R158-,A352S,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.9 2238 29 1.3% 2 +[T19R,T95I,E156G,F157-,R158-,A352S,L452R,Q677H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.1 2228 1361 61.1% 0 +[T95I,E154K,L452R,E484Q,P681R,Q1071H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.617.1 2228 95 4.3% 1 +[T95I,L452R,E484Q,P681R,Q1071H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.1 2228 54 2.4% 1 +[T95I,E154K,L452R,E484Q,P681R,Q1071H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.1 2228 41 1.8% 2 +[E154K,L452R,E484Q,P681R,Q1071H,H1101D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617.1 2228 41 1.8% 2 +[T95I,E154K,L452R,E484Q,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.18 2227 1612 72.4% 0 +[G75R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.18 2227 60 2.7% 1 +[G75R,A684V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.18 2227 58 2.6% 1 +[G75R,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.18 2227 58 2.6% 1 +[G75R,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.18 2227 58 2.6% 1 +[G75R,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.17 2223 1477 66.4% 0 (consensus) XBB.1.5.17 2223 80 3.6% 1 +[H146K]-[H146Q] XBB.1.5.17 2223 27 1.2% 2 +[S256L,F490P]-[F490S] XBB.1.5.17 2223 25 1.1% 1 +[N556K] XBB.1.5.17 2223 22 1.0% 1 -[K417N] BQ.1.1.32 2222 1570 70.7% 0 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.32 2222 90 4.1% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T1120S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.32 2222 47 2.1% 1 +[H69-,V70-,M153I,V213G,T323I,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.32 2222 35 1.6% 1 +[H69-,V70-,M153I,V213G,A260T,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.32 2222 26 1.2% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.10 2214 1744 78.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.10 2214 39 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.10 2214 30 1.4% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.10 2214 24 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.10 2214 24 1.1% 1 +[H69-,V70-,V213G,Q271E,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FL.2 2200 1398 63.5% 0 (consensus) FL.2 2200 51 2.3% 3 +[L141-,G142-,V143-]-[G142D] FL.2 2200 36 1.6% 1 +[T478R]-[T478K] FL.2 2200 30 1.4% 1 +[S256P] FL.2 2200 26 1.2% 1 -[K417N] BF.13 2199 1702 77.4% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.13 2199 52 2.4% 2 +[L5F,H69-,V70-,V213G,G339D,R346S,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.13 2199 36 1.6% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.13 2199 32 1.5% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.13 2199 23 1.0% 1 +[H69-,V70-,V213G,A222S,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.15 2191 1166 53.2% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.15 2191 295 13.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.15 2191 48 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A701V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.15 2191 45 2.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.15 2191 26 1.2% 1 +[H69-,V70-,E180G,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.20 2190 1597 72.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.20 2190 362 16.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A1070V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.20 2190 15 0.7% 1 +[H69-,V70-,V213G,L216F,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.20 2190 12 0.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,G1124V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.20 2190 10 0.5% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] P.1.1 2188 682 31.2% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.1 2188 475 21.7% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.1 2188 358 16.4% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,S813N,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.1 2188 60 2.7% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,S640F,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.1 2188 56 2.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E583D,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] JG.3 2176 1153 53.0% 0 +[Q52H,L455F,F456L,S704L] (consensus) JG.3 2176 199 9.1% 1 +[Q52H,T307I,L455F,F456L,S704L] JG.3 2176 116 5.3% 1 +[Q52H,N450D,L455F,F456L,S704L] JG.3 2176 33 1.5% 1 +[Q52H,L455F,F456L,S704L]-[T19I] JG.3 2176 30 1.4% 1 +[Q52H,H146K,L455F,F456L,S704L]-[H146Q] B.1.1.529 2131 191 9.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H] B.1.1.529 2131 41 1.9% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,L452R,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H] B.1.1.529 2131 30 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H] B.1.1.529 2131 29 1.4% 7 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H] B.1.1.529 2131 28 1.3% 10 +[T19R,A67V,H69-,V70-,T95I,V143-,Y145-,E156G,F157-,R158-,E554Q,N856K]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N764K,D796Y,N969K] BQ.1.13.1 2131 1614 75.7% 0 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.13.1 2131 34 1.6% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13.1 2131 32 1.5% 1 +[L5F,H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.13.1 2131 26 1.2% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.13.1 2131 19 0.9% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,E780G]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DY.1 2130 1577 74.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DY.1 2130 42 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S,N1125S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.1 2130 24 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.1 2130 24 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A570S,E1258D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.1 2130 18 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,A570S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.57 2123 1584 74.6% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.57 2123 37 1.7% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.57 2123 37 1.7% 1 +[T19R,S98F,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.57 2123 29 1.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,P1079S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.57 2123 25 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.4 2122 1609 75.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.4 2122 49 2.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.4 2122 39 1.8% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.4 2122 35 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.4 2122 24 1.1% 2 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.20 2114 1477 69.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.20 2114 135 6.4% 1 +[H69-,V70-,V213G,T259I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.20 2114 126 6.0% 1 +[A67S,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.20 2114 51 2.4% 2 +[H69-,V70-,K147N,V213G,S247N,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.20 2114 19 0.9% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.1.10 2110 1859 88.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.10 2110 40 1.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,Q1201K]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.10 2110 20 0.9% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.10 2110 19 0.9% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.10 2110 9 0.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.177.82 2106 1728 82.1% 0 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.82 2106 44 2.1% 1 +[A222V,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.82 2106 30 1.4% 1 +[T95N,A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.82 2106 26 1.2% 1 +[L18F,A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.82 2106 20 0.9% 1 +[A222V,A262S,P272L,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.1.4 2103 1572 74.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.4 2103 47 2.2% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4 2103 38 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.4 2103 36 1.7% 1 +[H69-,V70-,G184S,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.4 2103 26 1.2% 1 +[Q52H,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.582 2098 1469 70.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.582 2098 144 6.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.582 2098 45 2.1% 2 +[L5F,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.582 2098 43 2.0% 1 +[V1164F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.582 2098 27 1.3% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.5.4 2098 1645 78.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.5.4 2098 75 3.6% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,T572S,A1020S,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.4 2098 51 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G946R,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.4 2098 36 1.7% 1 +[H69-,V70-,V213G,T299I,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.4 2098 18 0.9% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.5 2096 1616 77.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.5 2096 81 3.9% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.9.5 2096 70 3.3% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.5 2096 16 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,N764K] BA.2.9.5 2096 14 0.7% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.37 2082 767 36.8% 0 +[T19R,E156G,F157-,R158-,A222V,V367L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.37 2082 333 16.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.37 2082 235 11.3% 1 +[T19R,E156G,F157-,R158-,A222V,V367L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.37 2082 164 7.9% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,Y508H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.37 2082 79 3.8% 3 +[T19R,E156G,F157-,R158-,A222V,L452R,Y508H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.27 2081 1406 67.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.27 2081 189 9.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V687I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.27 2081 67 3.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.27 2081 23 1.1% 4 +[H69-,V70-,V213G,G339D,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.27 2081 19 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1184Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.122.2 2080 1140 54.8% 0 +[T19R,E156G,F157-,R158-,A411S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.2 2080 282 13.6% 2 +[T19R,E156G,F157-,R158-,A411S,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.2 2080 247 11.9% 1 +[T19R,E156G,F157-,R158-,A411S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.2 2080 30 1.4% 1 +[T19R,E156G,F157-,R158-,A411S,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.2 2080 25 1.2% 1 +[T19R,E156G,F157-,R158-,A411S,L452R,P681R,D950N,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.10.2 2079 1746 84.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.10.2 2079 132 6.3% 31 +[R34L,A123S,V213G,R214L,G339D,A344S,+370F,A372P,S373F,T376-,A411S,V433F,G476C,Q493L,Q498L,R577L,R634L,R646L,A672S,R682L,R683L,R685L,R765L,G857C,R983L,R1091L,R1185L,D1199Y,D1260Y]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,N440K,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.10.2 2079 32 1.5% 1 +[F157L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.2 2079 25 1.2% 1 +[V213G,G339D,Q493R,S929N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.10.2 2079 22 1.1% 1 +[V213G,G339D,Q493R,L752F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.258.11 2076 981 47.3% 0 +[H69-,V70-,V143F,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.11 2076 593 28.6% 1 +[H69-,V70-,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.11 2076 131 6.3% 2 +[H69-,V70-,G261R,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.11 2076 90 4.3% 1 +[H69-,V70-,V143F,N439K,G1085A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.11 2076 52 2.5% 1 +[H69-,V70-,V143F,N439K,S673G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.560 2074 778 37.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.560 2074 330 15.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.560 2074 88 4.2% 2 +[F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.560 2074 40 1.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.560 2074 32 1.5% 1 +[Q218H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.45 2071 1997 96.4% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.45 2071 10 0.5% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.45 2071 5 0.2% 1 +[G75V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.45 2071 5 0.2% 1 +[V83F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.45 2071 4 0.2% 1 +[D80Y,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.23 2050 773 37.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.23 2050 741 36.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.23 2050 75 3.7% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.23 2050 24 1.2% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.23 2050 17 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.4.7 2042 1459 71.4% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.7 2042 242 11.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.7 2042 27 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.7 2042 23 1.1% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.7 2042 16 0.8% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.400 2041 976 47.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.400 2041 258 12.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.400 2041 178 8.7% 1 +[G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.400 2041 138 6.8% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.400 2041 85 4.2% 1 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.7 2008 988 49.2% 0 +[K97E,V213G,G339D,Q493R,G1251V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.7 2008 467 23.3% 1 +[K97E,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.7 2008 180 9.0% 1 +[K97E,V213G,G339D,Q493R,G1251V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.7 2008 71 3.5% 2 +[K97E,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.7 2008 61 3.0% 1 +[K97E,V213G,G339D,Q493R,G1251V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.40.1 1997 1520 76.1% 0 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.40.1 1997 102 5.1% 1 +[M177V,V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.40.1 1997 40 2.0% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.40.1 1997 23 1.2% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BA.2.40.1 1997 22 1.1% 1 +[V213G,G339D,K417T,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,K417N,V445P,G446S,N460K,F486P,F490S] AY.23.1 1991 1714 86.1% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.23.1 1991 45 2.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1230L,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.1 1991 26 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,E1188D,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.1 1991 13 0.7% 3 +[T19R,L452R,P681R,D950N,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.23.1 1991 9 0.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A694V,D950N,L1234I,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.92 1983 1056 53.3% 0 +[T19R,T95I,E156G,F157-,R158-,D178N,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.92 1983 206 10.4% 1 +[T19R,T95I,E156G,F157-,R158-,D178N,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.92 1983 155 7.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.92 1983 59 3.0% 1 +[T19R,T95I,E156G,F157-,R158-,D178N,L242F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.92 1983 38 1.9% 1 +[T19R,T95I,E156G,F157-,R158-,D178N,L452R,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.8 1966 1715 87.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AE.8 1966 16 0.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.8 1966 14 0.7% 1 +[I1216L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.8 1966 13 0.7% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AE.8 1966 11 0.6% 1 +[V736I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.36 1949 1207 61.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.36 1949 506 26.0% 1 +[P26S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.36 1949 33 1.7% 1 +[P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.36 1949 22 1.1% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.36 1949 21 1.1% 2 +[P26S,Q1201K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.7 1930 1621 84.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.7 1930 47 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.7 1930 34 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.7 1930 17 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1101Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.7 1930 10 0.5% 1 +[S12F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.48 1927 1673 86.8% 0 +[V213G,Y248S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.48 1927 63 3.3% 1 +[V213G,Y248S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.48 1927 18 0.9% 1 +[V213G,Y248S,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.48 1927 7 0.4% 2 +[V83F,V213G,Y248S,G339D,Q493R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.48 1927 6 0.3% 1 +[V213G,Y248S,G339D,Q493R,G1171S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.317 1922 687 35.7% 0 +[D138Y,A522S,Q675R,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.317 1922 378 19.7% 5 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.317 1922 83 4.3% 1 +[D138Y,Q675R,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.317 1922 57 3.0% 3 +[A522S,Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.317 1922 57 3.0% 1 +[D138Y,A222V,A522S,Q675R,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.2 1919 1495 77.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.2 1919 53 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.2 1919 31 1.6% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.2 1919 23 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.2 1919 22 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1122L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.517 1911 922 48.2% 0 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.517 1911 322 16.8% 1 +[N501T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.517 1911 160 8.4% 2 +[N501T,Q613H,S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.517 1911 93 4.9% 1 +[N501T,V1133A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.517 1911 52 2.7% 1 +[N501T,Q613H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.79 1908 1063 55.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.79 1908 209 11.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.79 1908 25 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.79 1908 21 1.1% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.79 1908 19 1.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.6 1899 1466 77.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.6 1899 77 4.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.6 1899 63 3.3% 1 +[V213G,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.6 1899 48 2.5% 1 +[I210V,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.6 1899 30 1.6% 1 +[V213G,G339D,Q493R,D1259H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.16.15 1897 1387 73.1% 0 +[K147N,E180V,T478R,P521S]-[T478K] (consensus) XBB.1.16.15 1897 74 3.9% 1 +[K147N,E180V,T478R,P521S,T732I]-[T478K] XBB.1.16.15 1897 25 1.3% 1 +[K147N,E180V,T478R,P521S,V1228L]-[T478K] XBB.1.16.15 1897 20 1.1% 1 +[K147N,E180V,T478R,P521S,S704L]-[T478K] XBB.1.16.15 1897 17 0.9% 1 +[K147N,E180V,T478R]-[T478K] CL.1 1893 1123 59.3% 0 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CL.1 1893 62 3.3% 5 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CL.1 1893 47 2.5% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] CL.1 1893 47 2.5% 1 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N764K] CL.1 1893 35 1.8% 2 +[H69-,V70-,K150E,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,N764K,D796Y] EF.1 1889 1306 69.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EF.1 1889 77 4.1% 1 +[H69-,V70-,E132Q,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1 1889 45 2.4% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1 1889 30 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EF.1 1889 15 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q836L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.561 1887 1188 63.0% 0 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.561 1887 412 21.8% 1 +[D138Y,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.561 1887 18 1.0% 3 +[D138Y,S939F,V1230A,T1238I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.561 1887 16 0.8% 2 +[D138Y,D178E,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.561 1887 11 0.6% 1 +[D138Y,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.18 1872 1456 77.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.18 1872 46 2.5% 1 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.18 1872 30 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.18 1872 17 0.9% 1 +[H69-,V70-,V159I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.18 1872 17 0.9% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] P.1.16 1870 1441 77.1% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.16 1870 38 2.0% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E471Q,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.16 1870 29 1.6% 1 +[L18F,T20N,P26S,D138Y,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.16 1870 22 1.2% 1 +[L5F,L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.16 1870 21 1.1% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,K528I,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.2 1866 964 51.7% 0 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.2 1866 450 24.1% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.2 1866 41 2.2% 2 +[H69-,V70-,N99D,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.2 1866 35 1.9% 1 +[H69-,V70-,H146-,V213G,D253G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.2 1866 25 1.3% 2 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,D1260H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25 1851 1098 59.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.25 1851 97 5.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25 1851 89 4.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.25 1851 51 2.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T791A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25 1851 49 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.5.2.19 1847 1234 66.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.19 1847 95 5.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1083Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.19 1847 83 4.5% 4 +[H69-,V70-,L179F,G339D,N450D,L452R,F486V,F1075L]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.19 1847 44 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.19 1847 34 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1127A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FL.5 1843 1109 60.2% 0 (consensus) FL.5 1843 35 1.9% 1 +[T478R]-[T478K] FL.5 1843 32 1.7% 1 +[H146K]-[H146Q] FL.5 1843 28 1.5% 1 +[I651V] FL.5 1843 17 0.9% 1 -[R408S] AY.41 1833 742 40.5% 0 +[T19R,E156G,F157-,R158-,A262S,L452R,S477I,P681R,D950N,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.41 1833 509 27.8% 1 +[T19R,E156G,F157-,R158-,A262S,L452R,S477I,P681R,D950N,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.41 1833 32 1.7% 1 +[T19R,E156G,F157-,R158-,A262S,L452R,S477I,Q613H,P681R,D950N,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.41 1833 25 1.4% 2 +[T19R,E156G,F157-,R158-,A262S,L452R,S477I,Q613H,P681R,D950N,G1167V,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.41 1833 25 1.4% 1 +[T19R,E156G,F157-,R158-,A262S,L452R,S477I,T678I,P681R,D950N,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.307 1819 1269 69.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.307 1819 335 18.4% 1 +[G261V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.307 1819 28 1.5% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.307 1819 17 0.9% 1 +[C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.307 1819 17 0.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.32 1814 1100 60.6% 0 (consensus) XBB.1.5.32 1814 236 13.0% 1 +[T883I] XBB.1.5.32 1814 38 2.1% 1 +[D796H]-[D796Y] XBB.1.5.32 1814 21 1.2% 6 -[R408S,K417N,N440K,V445P,G446S,N460K] XBB.1.5.32 1814 19 1.0% 1 +[L335F] XAZ 1812 1318 72.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) XAZ 1812 63 3.5% 1 +[H69-,V70-,P82L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XAZ 1812 44 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XAZ 1812 37 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] XAZ 1812 30 1.7% 1 +[H69-,V70-,V213G,G339D,R346I,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] JN.1 1810 1275 70.4% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) JN.1 1810 112 6.2% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1 1810 34 1.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L,M1229I]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1 1810 21 1.2% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] JN.1 1810 14 0.8% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BQ.1.3.1 1809 1062 58.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.3.1 1809 136 7.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.1 1809 58 3.2% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.1 1809 45 2.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3.1 1809 40 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBB.1.5.37 1808 1129 62.4% 0 +[K1045R] (consensus) XBB.1.5.37 1808 66 3.7% 1 +[F456L,K1045R] XBB.1.5.37 1808 45 2.5% 1 +[K1045R]-[K417N] XBB.1.5.37 1808 28 1.5% 1 +[H146K,K1045R]-[H146Q] XBB.1.5.37 1808 20 1.1% 2 +[K1045R]-[R408S,S477N] B.1.1.25 1803 1005 55.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.25 1803 193 10.7% 1 +[P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.25 1803 126 7.0% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.25 1803 15 0.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.25 1803 14 0.8% 1 +[V6I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DY.3 1799 1469 81.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DY.3 1799 20 1.1% 1 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.3 1799 9 0.5% 1 +[H69-,V70-,V83F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.3 1799 8 0.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] DY.3 1799 8 0.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,F1121L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.45 1793 1217 67.9% 0 +[H69-,V70-,V213G,Y248D,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.45 1793 34 1.9% 1 +[H69-,V70-,V213G,Y248D,G339D,K444T,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.45 1793 24 1.3% 1 +[H69-,V70-,V213G,Y248D,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.45 1793 18 1.0% 1 +[H69-,V70-,V213G,Y248D,G339D,K444T,G446V,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.45 1793 17 0.9% 1 +[H69-,V70-,V213G,Y248D,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,V445P,G446S,F486P,F490S] AY.34.1.1 1784 857 48.0% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.34.1.1 1784 197 11.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1.1 1784 106 5.9% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1.1 1784 68 3.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.1.1 1784 32 1.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,D950N,A1078S,L1265F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DN.2 1781 1397 78.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DN.2 1781 56 3.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.2 1781 53 3.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.2 1781 21 1.2% 1 +[H69-,V70-,F186L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DN.2 1781 15 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F456L,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.5.3.3 1781 1526 85.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3.3 1781 19 1.1% 1 +[H69-,V70-,Q183K,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.3 1781 16 0.9% 1 +[H69-,V70-,V213G,H245Y,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.3 1781 12 0.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.3 1781 9 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,K921R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.18 1779 1061 59.6% 0 +[H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.18 1779 70 3.9% 1 +[H69-,V70-,L212S,V213G,G339D,K444R,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.18 1779 65 3.7% 2 +[H69-,V70-,H146-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.18 1779 36 2.0% 2 +[H69-,V70-,G181V,V213G,G339D,K444R,L452R,F486V,I934V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.18 1779 29 1.6% 1 +[H69-,V70-,V213G,G339D,K444R,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.23 1778 1254 70.5% 0 +[H69-,V70-,Y145H,V213G,S255F,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.23 1778 89 5.0% 1 +[H69-,V70-,V213G,S255F,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.23 1778 62 3.5% 1 +[H69-,V70-,Y145H,V213G,S255F,G339D,V445A,L452R,F486V,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.23 1778 29 1.6% 1 +[H69-,V70-,Y145H,V213G,S255F,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.23 1778 22 1.2% 1 +[H69-,V70-,Y145H,V213G,S255F,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] BQ.1.1.8 1775 1027 57.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.8 1775 389 21.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.8 1775 20 1.1% 1 +[H69-,V70-,K150N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.8 1775 15 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.8 1775 14 0.8% 1 +[H69-,V70-,K147N,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.5.1.12 1767 957 54.2% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.12 1767 205 11.6% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,A1070V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.12 1767 70 4.0% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.12 1767 49 2.8% 2 +[H69-,V70-,V213G,S255F,G339D,V445A,L452R,F486V,T747I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.12 1767 36 2.0% 2 +[H69-,V70-,N185D,V213G,G339D,V445A,L452R,F486V,A1070V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.116 1740 791 45.5% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.116 1740 212 12.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116 1740 192 11.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116 1740 51 2.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,V772I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.116 1740 35 2.0% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.17 1739 1591 91.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.17 1739 21 1.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.3.17 1739 21 1.2% 1 +[V213G,L216F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.17 1739 14 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.17 1739 9 0.5% 1 +[V213G,G339D,Q493R,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] Q.4 1727 1380 79.9% 0 +[H69-,V70-,A570D,P681R,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) Q.4 1727 46 2.7% 1 +[H69-,V70-,R408G,A570D,P681R,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Q.4 1727 23 1.3% 1 +[H69-,V70-,A570D,P681R,T716I,S943P,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Q.4 1727 22 1.3% 1 +[H69-,V70-,V308L,A570D,P681R,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Q.4 1727 19 1.1% 1 +[L5F,H69-,V70-,A570D,P681R,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.21 1722 1291 75.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.21 1722 176 10.2% 1 +[V213G,G339D,Q493R,Q1113K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.21 1722 58 3.4% 1 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.21 1722 23 1.3% 1 +[V213G,G339D,Q493R,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.21 1722 22 1.3% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] XBB.1.5.24 1718 1045 60.8% 0 (consensus) XBB.1.5.24 1718 38 2.2% 1 +[T883I] XBB.1.5.24 1718 27 1.6% 1 +[L5F] XBB.1.5.24 1718 23 1.3% 1 +[H146K]-[H146Q] XBB.1.5.24 1718 23 1.3% 1 -[R408S] B.1.1.306 1711 779 45.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.306 1711 131 7.7% 4 +[L18F,E484K,Q675H]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.306 1711 121 7.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.306 1711 48 2.8% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.306 1711 33 1.9% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.2 1710 1149 67.2% 0 +[T19R,V70F,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.2 1710 272 15.9% 1 +[T19R,V70F,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.2 1710 26 1.5% 1 +[T19R,V70F,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.2 1710 22 1.3% 2 +[T19R,V70F,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.2 1710 20 1.2% 1 +[T19R,V70F,E156G,F157-,R158-,A222V,K356N,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.15 1696 946 55.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.15 1696 160 9.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.15 1696 122 7.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.15 1696 48 2.8% 1 +[H69-,V70-,V213G,V289I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.15 1696 39 2.3% 1 +[H69-,V70-,S98F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.619.1 1691 1435 84.9% 0 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.619.1 1691 66 3.9% 1 +[T20I,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619.1 1691 17 1.0% 1 +[G75V,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619.1 1691 11 0.7% 1 +[L18F,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619.1 1691 10 0.6% 1 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.3.8 1689 1222 72.4% 0 +[D253G,T478R,P521S]-[G252V,T478K] (consensus) XBB.2.3.8 1689 25 1.5% 1 +[H146K,D253G,T478R,P521S]-[H146Q,G252V,T478K] XBB.2.3.8 1689 22 1.3% 1 +[D253G,S255F,T478R,P521S]-[G252V,T478K] XBB.2.3.8 1689 12 0.7% 2 +[V213D,R246K,D253G,T478R,P521S]-[V213E,G252V,T478K] XBB.2.3.8 1689 11 0.7% 1 +[T51I,D253G,T478R,P521S]-[G252V,T478K] FY.3.1 1671 659 39.4% 0 +[H146K,Y200C,I210T]-[H146Q] (consensus) FY.3.1 1671 397 23.8% 1 +[Y200C,I210T] FY.3.1 1671 64 3.8% 3 +[Y200C,I210T,L244F,H245-] FY.3.1 1671 43 2.6% 2 +[Y200C,I210T,P384H] FY.3.1 1671 36 2.2% 2 +[Y200C,I210T,Q493L] XBB.2.3.2 1668 1000 60.0% 0 +[G184V,D253G,P521S]-[G252V] (consensus) XBB.2.3.2 1668 55 3.3% 1 +[K147N,G184V,D253G,P521S]-[G252V] XBB.2.3.2 1668 38 2.3% 1 +[H146K,G184V,D253G,P521S]-[H146Q,G252V] XBB.2.3.2 1668 21 1.3% 1 +[L5F,G184V,D253G,P521S]-[G252V] XBB.2.3.2 1668 20 1.2% 1 +[G184V,D253G,P521S,S929T]-[G252V] XBB.1.5.10 1668 1173 70.3% 0 +[F456L] (consensus) XBB.1.5.10 1668 44 2.6% 1 +[F456L,I569V] XBB.1.5.10 1668 35 2.1% 1 +[F456L]-[K417N] XBB.1.5.10 1668 35 2.1% 1 +[H146K,F456L]-[H146Q] XBB.1.5.10 1668 30 1.8% 1 +[L8F,F456L] BE.11 1667 1374 82.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.11 1667 99 5.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.11 1667 23 1.4% 1 +[H69-,V70-,G181R,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.11 1667 16 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.11 1667 9 0.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.40 1650 1183 71.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.40 1650 58 3.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.40 1650 57 3.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.40 1650 23 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,G1124V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.40 1650 18 1.1% 6 +[L24S,P25Y,Y28-,T29-,H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[L24-,P25-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.577 1641 938 57.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.577 1641 119 7.3% 1 +[I834T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.577 1641 105 6.4% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.577 1641 31 1.9% 1 +[R21K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.577 1641 30 1.8% 2 +[Q52R,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.17 1637 1164 71.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.17 1637 69 4.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.17 1637 50 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.17 1637 24 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,M740I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.17 1637 18 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.8 1633 1286 78.8% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.8 1633 40 2.4% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.8 1633 17 1.0% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.8 1633 12 0.7% 1 +[V3G,H69-,V70-,W152L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.8 1633 10 0.6% 3 +[V3G,H69-,V70-,W152L,N211-,L212I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.31 1630 911 55.9% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.31 1630 273 16.7% 1 +[V213G,G339D,Q493R,N925S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.31 1630 165 10.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.31 1630 66 4.0% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.31 1630 28 1.7% 2 +[H69-,V70-,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.7 1624 1158 71.3% 0 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.7 1624 85 5.2% 1 +[H69-,V70-,V213G,Y248H,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.7 1624 24 1.5% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,H655Y] BA.5.2.7 1624 23 1.4% 1 +[H69-,V70-,V213G,T299I,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.7 1624 23 1.4% 5 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.36.17 1605 1318 82.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.17 1605 38 2.4% 1 +[R102I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.17 1605 36 2.2% 1 +[A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.17 1605 15 0.9% 1 +[V308L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.17 1605 9 0.6% 1 +[G946V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.20 1600 973 60.8% 0 (consensus) XBB.1.5.20 1600 62 3.9% 1 +[Q954Y]-[Q954H] XBB.1.5.20 1600 41 2.6% 1 +[H146K]-[H146Q] XBB.1.5.20 1600 33 2.1% 1 -[K417N] XBB.1.5.20 1600 33 2.1% 1 -[R408S] BA.5.2.57 1600 976 61.0% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.57 1600 89 5.6% 1 +[H69-,V70-,L176F,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.57 1600 70 4.4% 1 +[H69-,V70-,V213G,P251L,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.57 1600 39 2.4% 1 +[H69-,V70-,H146Y,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.57 1600 36 2.2% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.1.1 1600 828 51.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.1.1 1600 166 10.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T859S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1.1 1600 65 4.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1.1 1600 40 2.5% 1 +[H69-,V70-,V213G,G339D,D420N,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.1.1 1600 33 2.1% 1 +[H69-,V70-,V213G,T299I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.5.3 1599 978 61.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.5.3 1599 282 17.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.3 1599 32 2.0% 2 +[T19R,E156G,F157-,R158-,A263V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.3 1599 30 1.9% 1 +[T19R,E156G,F157-,R158-,A263V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.5.3 1599 16 1.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596 1596 888 55.6% 0 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.596 1596 66 4.1% 2 +[Q677P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596 1596 60 3.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596 1596 50 3.1% 1 +[T20I,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.596 1596 34 2.1% 1 +[D627H,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.2 1595 1328 83.3% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.2 1595 26 1.6% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.2 1595 17 1.1% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.2 1595 9 0.6% 1 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.2 1595 8 0.5% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.13 1593 1217 76.4% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.13 1593 55 3.5% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.13 1593 37 2.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.13 1593 24 1.5% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.13 1593 17 1.1% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,V622I,A706V,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BF.22 1591 1338 84.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.22 1591 50 3.1% 1 +[H69-,V70-,V213G,T323A,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.22 1591 33 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1251V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.22 1591 21 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.22 1591 20 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2.1 1588 1153 72.6% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.2.1 1588 44 2.8% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,E554A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2.1 1588 26 1.6% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2.1 1588 20 1.3% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,T638R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2.1 1588 17 1.1% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] AY.45 1581 677 42.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.45 1581 270 17.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.45 1581 126 8.0% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,P792S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.45 1581 43 2.7% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,T747I,D936N,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.45 1581 30 1.9% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.1 1579 700 44.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.1 1579 415 26.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.1 1579 52 3.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.1 1579 21 1.3% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I,D950N,L1049I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.1 1579 21 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,T791I,D950N,L1203F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.16 1576 1311 83.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.16 1576 59 3.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,Q1208H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.16 1576 30 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1006I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.16 1576 27 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.16 1576 25 1.6% 1 +[H69-,V70-,V213G,D215G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BM.1.1.3 1572 917 58.3% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.1.1.3 1572 47 3.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.3 1572 33 2.1% 1 +[K147E,W152R,F157L,N185T,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.3 1572 32 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,F490P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1.3 1572 29 1.8% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BK.1 1567 1222 78.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BK.1 1567 51 3.3% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BK.1 1567 31 2.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BK.1 1567 15 1.0% 2 +[L5F,H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BK.1 1567 12 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EG.1.6 1555 916 58.9% 0 +[Q613H] (consensus) EG.1.6 1555 106 6.8% 1 +[H146K,Q613H]-[H146Q] EG.1.6 1555 53 3.4% 1 +[Q613H,V642-] EG.1.6 1555 41 2.6% 1 +[N148T,Q613H] EG.1.6 1555 35 2.3% 1 +[Q613H,G1124V] XB 1555 861 55.4% 0 +[L18R,T95I,R158S,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) XB 1555 109 7.0% 1 +[L18R,T95I,R158S,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XB 1555 48 3.1% 1 +[L18R,T95I,R158S,A688V,S735A,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XB 1555 39 2.5% 1 +[L18R,T95I,R158S,A688V,S735A,T1027I,Y1206F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XB 1555 28 1.8% 2 +[L18R,T95I,R158S,E484Q,A688V,S735A,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BF.7.21 1554 1078 69.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.21 1554 67 4.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.21 1554 32 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1267E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.21 1554 31 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.21 1554 22 1.4% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.55 1551 1073 69.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.55 1551 197 12.7% 1 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.55 1551 49 3.2% 2 +[H69-,V70-,N164K,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.55 1551 31 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,E702D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.55 1551 15 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T1009I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.94 1549 581 37.5% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.94 1549 542 35.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.94 1549 65 4.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.94 1549 54 3.5% 2 +[T19R,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.94 1549 28 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,A475V,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.40 1548 1275 82.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.40 1548 29 1.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.40 1548 24 1.6% 1 +[A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.40 1548 20 1.3% 1 +[A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.40 1548 14 0.9% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.38 1548 1212 78.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.38 1548 83 5.4% 1 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38 1548 31 2.0% 1 +[H69-,V70-,D111N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38 1548 21 1.4% 2 +[A67V,H69-,V70-,V213G,G339D,L452R,F486V,K1073N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.38 1548 20 1.3% 1 +[H69-,V70-,V213G,V308L,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.10 1545 905 58.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BE.10 1545 93 6.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.10 1545 46 3.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BE.10 1545 39 2.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BE.10 1545 35 2.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,F486P,F490S] B.1.128 1543 1224 79.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.128 1543 142 9.2% 1 +[P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.128 1543 60 3.9% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.128 1543 21 1.4% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.128 1543 15 1.0% 2 +[P809S,G1085E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] JF.1 1534 1209 78.8% 0 +[E180V,L455F,F456L,T478R]-[T478K] (consensus) JF.1 1534 50 3.3% 1 +[H146K,E180V,L455F,F456L,T478R]-[H146Q,T478K] JF.1 1534 32 2.1% 1 +[E180V,L455F,F456L,A475V,T478R]-[T478K] JF.1 1534 15 1.0% 2 +[Q14H,E180V,L455F,F456L,T478R,S810L]-[T478K] JF.1 1534 15 1.0% 1 +[E180V,L455F,F456L,T478R,G482R]-[T478K] B.1.1.39 1534 563 36.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.39 1534 396 25.8% 1 +[S673T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.39 1534 125 8.1% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.39 1534 55 3.6% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.39 1534 37 2.4% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.53 1531 686 44.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.53 1531 408 26.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.53 1531 42 2.7% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.53 1531 24 1.6% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.53 1531 18 1.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,C1253F]-[T19I,L24-,P25-,P26-,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.2 1516 870 57.4% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.39.2 1516 332 21.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.2 1516 22 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,V635A,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.2 1516 20 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.39.2 1516 15 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.75 1516 597 39.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75 1516 148 9.8% 4 +[K147E,W152R,F157L,I210V,V213G,G257S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75 1516 42 2.8% 3 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75 1516 39 2.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75 1516 21 1.4% 5 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,G446S,F486P,F490S] BN.1.2.2 1513 1030 68.1% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.2 1513 108 7.1% 1 +[K147E,W152R,F157L,I210V,V213G,A222V,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.2 1513 18 1.2% 1 +[H49Y,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.2 1513 15 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.2 1513 15 1.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A942S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] CH.1.1.2 1501 1057 70.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.2 1501 36 2.4% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.2 1501 31 2.1% 1 +[I68T,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.2 1501 31 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P809Q,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.2 1501 21 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T549I,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.4.4 1500 839 55.9% 0 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.4 1500 185 12.3% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.4 1500 30 2.0% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,Q853H,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.4 1500 25 1.7% 1 +[L5F,T19R,G75V,T95I,E156G,F157-,R158-,L452R,P681R,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.4 1500 23 1.5% 2 +[L5F,T19R,G75V,T95I,E156G,F157-,R158-,L452R,P681R,S929T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.3.2 1499 1224 81.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3.2 1499 47 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.3.2 1499 29 1.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BA.5.3.2 1499 17 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.2 1499 8 0.5% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.177.35 1496 1157 77.3% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.35 1496 68 4.5% 1 +[A222V,I410V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.35 1496 60 4.0% 1 +[L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.35 1496 27 1.8% 1 +[A222V]-[L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.35 1496 17 1.1% 1 +[A222V,C1243F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.106 1491 523 35.1% 0 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.106 1491 224 15.0% 1 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.106 1491 101 6.8% 1 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R,D950N,A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.106 1491 54 3.6% 2 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R,D950N,A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.106 1491 28 1.9% 2 +[T19R,T95I,E156G,F157-,R158-,S255F,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.10 1484 1273 85.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.10 1484 41 2.8% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.10 1484 12 0.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.10 1484 12 0.8% 2 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.10 1484 11 0.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N,C1236F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.68 1483 975 65.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.68 1483 156 10.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.68 1483 64 4.3% 1 +[V36I,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.68 1483 17 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,M1237T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.68 1483 16 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E554K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.10.1 1482 1052 71.0% 0 +[H69-,V70-,H146L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.10.1 1482 148 10.0% 2 +[H69-,V70-,Y145L,H146-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10.1 1482 19 1.3% 1 +[H69-,V70-,H146L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.10.1 1482 14 0.9% 1 +[H66Y,H69-,V70-,H146L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.10.1 1482 12 0.8% 1 +[H69-,V70-,H146L,V213G,G339D,K444T,L452R,F486V,A1020V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] EF.1.1 1476 1097 74.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EF.1.1 1476 53 3.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1.1 1476 32 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] EF.1.1 1476 22 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,G446R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EF.1.1 1476 16 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] A.2.5 1469 569 38.7% 0 +[L141-,G142-,V143-,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2.5 1469 80 5.4% 4 +[L141-,G142-,V143-,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5 1469 75 5.1% 3 +[D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5 1469 43 2.9% 1 +[L141-,G142-,V143-,D215A,+215AGY,L452R,G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2.5 1469 32 2.2% 2 +[L141-,G142-,V143-,D215A,+215AGY,L452R,T739I,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.22 1466 1189 81.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.22 1466 20 1.4% 1 +[H69-,V70-,V213G,A260V,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.22 1466 20 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.22 1466 15 1.0% 1 +[H69-,V70-,W152L,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.22 1466 13 0.9% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E1150D,E1202Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BF.36 1465 1132 77.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.36 1465 63 4.3% 1 +[H69-,V70-,V213G,Q271E,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.36 1465 49 3.3% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.36 1465 15 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.36 1465 13 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.1.298 1460 980 67.1% 0 +[H69-,V70-,Y453F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.298 1460 148 10.1% 1 +[H69-,V70-,Y453F,S1147L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.298 1460 108 7.4% 2 +[Y453F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.298 1460 30 2.1% 3 +[L5F,H69-,V70-,Y453F,N751Y,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.298 1460 18 1.2% 1 +[H69-,V70-,Y453F,G1167V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.609 1457 769 52.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.609 1457 289 19.8% 3 +[L5F,L176F,T478R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.609 1457 35 2.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.609 1457 17 1.2% 3 +[G75V,Q779R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.609 1457 15 1.0% 1 +[N679S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.16 1444 1017 70.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.16 1444 36 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.16 1444 35 2.4% 2 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.16 1444 23 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.16 1444 23 1.6% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.1.41 1444 885 61.3% 0 +[H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.41 1444 63 4.4% 1 +[H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V,I931V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.41 1444 54 3.7% 1 +[H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.41 1444 43 3.0% 1 +[H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.41 1444 43 3.0% 1 +[L5F,H69-,V70-,K182I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.279 1441 701 48.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.279 1441 317 22.0% 1 +[L1224F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.279 1441 268 18.6% 2 +[L18F,L1224F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.279 1441 43 3.0% 1 +[Y28H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.279 1441 16 1.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.48 1431 964 67.4% 0 (consensus) XBB.1.5.48 1431 47 3.3% 1 -[K417N] XBB.1.5.48 1431 35 2.4% 1 +[H146K]-[H146Q] XBB.1.5.48 1431 18 1.3% 1 +[N148T] XBB.1.5.48 1431 16 1.1% 1 +[T478R]-[T478K] FL.2.3 1428 809 56.7% 0 (consensus) FL.2.3 1428 219 15.3% 1 +[H146K]-[H146Q] FL.2.3 1428 27 1.9% 1 +[F456L] FL.2.3 1428 23 1.6% 1 +[V642G] FL.2.3 1428 18 1.3% 2 +[H146K,P521S]-[H146Q] FD.2 1425 953 66.9% 0 +[H146K]-[H146Q] (consensus) FD.2 1425 144 10.1% 1 FD.2 1425 13 0.9% 1 +[H146K,T307I]-[H146Q] FD.2 1425 13 0.9% 1 +[H146K]-[Y144-,H146Q] FD.2 1425 12 0.8% 1 +[V70G,H146K]-[H146Q] BF.39 1418 1102 77.7% 0 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.39 1418 66 4.7% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.39 1418 26 1.8% 1 +[H69-,V70-,G181V,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.39 1418 12 0.8% 2 +[H69F,V70-,S71-,G181V,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.39 1418 12 0.8% 1 +[H69-,V70-,G181V,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.34 1410 997 70.7% 0 +[H69-,V70-,K147-,N149-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.34 1410 185 13.1% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.34 1410 50 3.5% 1 +[H69-,V70-,K147-,N149-,V213G,G339D,L452R,F486V,P1162S,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.34 1410 30 2.1% 1 +[H69-,V70-,K147-,N149-,V213G,L216F,G339D,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.34 1410 17 1.2% 1 +[H69-,V70-,K147-,N149-,V213G,G339D,L452R,F486V,P1162S,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.3.5 1409 964 68.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.5 1409 71 5.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E471Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.5 1409 26 1.8% 2 +[H69-,V70-,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.5 1409 21 1.5% 1 +[G75S,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.5 1409 16 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.110.3 1405 1090 77.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.110.3 1405 52 3.7% 1 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110.3 1405 34 2.4% 1 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110.3 1405 17 1.2% 1 +[I210V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.110.3 1405 15 1.1% 1 +[S373L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.33 1397 934 66.9% 0 (consensus) XBB.1.5.33 1397 55 3.9% 1 +[R237K] XBB.1.5.33 1397 32 2.3% 1 +[T883I] XBB.1.5.33 1397 25 1.8% 1 +[H146K]-[H146Q] XBB.1.5.33 1397 23 1.6% 1 -[K417N] B.1.623 1397 731 52.3% 0 +[S494P,K854N,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.623 1397 390 27.9% 1 +[S494P,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.623 1397 35 2.5% 1 +[T385I,S494P,K854N,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.623 1397 28 2.0% 2 +[T95I,S494P,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.623 1397 17 1.2% 2 +[S494P,T678I,E1111K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.43.4 1396 276 19.8% 0 +[T19R,E156G,F157-,R158-,K356R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.4 1396 271 19.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.4 1396 218 15.6% 1 +[T19R,E156G,F157-,R158-,K356R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.4 1396 207 14.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.4 1396 80 5.7% 2 +[T19R,E156G,F157-,R158-,K356R,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FD.1.1 1394 993 71.2% 0 +[F456L] (consensus) FD.1.1 1394 35 2.5% 1 +[H146K,F456L]-[H146Q] FD.1.1 1394 30 2.2% 1 +[L5F,F456L] FD.1.1 1394 22 1.6% 1 +[R102G,F456L] FD.1.1 1394 18 1.3% 1 +[F456L,P812L] B.1.36.29 1393 631 45.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.29 1393 141 10.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.29 1393 27 1.9% 1 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.29 1393 19 1.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.36.29 1393 14 1.0% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.44 1389 1108 79.8% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.44 1389 45 3.2% 1 +[S98F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.44 1389 25 1.8% 1 +[A222V,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.44 1389 24 1.7% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.44 1389 12 0.9% 1 +[L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.11 1386 865 62.4% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.11 1386 115 8.3% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.11 1386 86 6.2% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.11 1386 37 2.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.1.11 1386 22 1.6% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,N440K,V445P,N460K,F486P,F490S] B.1.621.1 1384 992 71.7% 0 +[T95I,+143T,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.621.1 1384 61 4.4% 1 +[T95I,Y144S,Y145N,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621.1 1384 26 1.9% 2 +[T95I,Y144S,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621.1 1384 20 1.4% 1 +[T95I,+143T,Y144S,Y145N,R346K,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.621.1 1384 16 1.2% 3 +[T95I,R346K,E484K,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.5.2.43 1380 1066 77.2% 0 +[H69-,V70-,K147Q,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BA.5.2.43 1380 35 2.5% 1 +[H69-,V70-,K147Q,V213G,G339D,G446D,L452R,F486V,L1265P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.43 1380 17 1.2% 1 +[H69-,V70-,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.43 1380 13 0.9% 3 +[H69-,V70-,E154D,V213G,G339D,G446D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.2.43 1380 9 0.7% 1 +[V62L,H69-,V70-,K147Q,V213G,G339D,G446D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DL.1 1379 756 54.8% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) DL.1 1379 79 5.7% 1 +[H69-,V70-,K147N,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DL.1 1379 51 3.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DL.1 1379 41 3.0% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DL.1 1379 38 2.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q677H]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.1.19 1376 952 69.2% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.19 1376 64 4.7% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.19 1376 59 4.3% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,V445P,N460K,F486P,F490S] BA.1.19 1376 46 3.3% 5 +[A67V,H69-,V70-,T95I,V143-,Y145-,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.19 1376 23 1.7% 4 +[H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] AY.38 1373 304 22.1% 0 +[T19R,E156G,F157-,R158-,A222V,T250S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.38 1373 189 13.8% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.38 1373 174 12.7% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.38 1373 149 10.9% 3 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.38 1373 97 7.1% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.565 1371 889 64.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.565 1371 182 13.3% 1 +[A1070S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.565 1371 29 2.1% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.565 1371 25 1.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.565 1371 21 1.5% 1 +[E309Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.35 1369 1055 77.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.35 1369 35 2.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.35 1369 31 2.3% 1 +[H69-,V70-,F157L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.35 1369 23 1.7% 1 +[H69-,V70-,V213G,A260T,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.35 1369 19 1.4% 1 +[H69-,V70-,G184D,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.62 1361 618 45.4% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.62 1361 334 24.5% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.62 1361 36 2.6% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,N978S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.62 1361 33 2.4% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,G946V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.62 1361 32 2.4% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] None 1354 110 8.1% 0 +[Q52H,F456L] None 1354 89 6.6% 2 +[Q52H,F157L,L452R,F456L] None 1354 75 5.5% 1 +[Q52H,L455F,F456L] None 1354 71 5.2% 42 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] None 1354 61 4.5% 3 +[L455F,F456L,A475V] XBB.1.16.2 1353 845 62.5% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.2 1353 82 6.1% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.2 1353 30 2.2% 1 +[E180V,T478R]-[K417N,T478K] XBB.1.16.2 1353 24 1.8% 1 +[L5I,E180V,T478R]-[T478K] XBB.1.16.2 1353 15 1.1% 1 +[E180V,N317S,T478R]-[T478K] BQ.1.1.13 1349 706 52.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.13 1349 164 12.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.13 1349 62 4.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S939F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.13 1349 31 2.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.13 1349 26 1.9% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I651V,T1066N]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.1.1.4 1346 1208 89.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.4 1346 32 2.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.4 1346 13 1.0% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.4 1346 11 0.8% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.4 1346 10 0.7% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,H625R,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.232 1346 665 49.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.232 1346 402 29.9% 1 +[L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.232 1346 63 4.7% 1 +[R346K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.232 1346 36 2.7% 1 +[A475S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.232 1346 9 0.7% 2 +[L452R,G639S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BG.5 1345 1090 81.0% 0 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BG.5 1345 37 2.8% 1 +[V213G,G339D,L452Q,Q493R,S704L,T1077A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.5 1345 35 2.6% 1 +[F32L,V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.5 1345 22 1.6% 1 +[F157L,V213G,G339D,L452Q,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.5 1345 12 0.9% 1 +[V213G,G339D,L452Q,Q493R,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.68 1329 675 50.8% 0 +[T19R,E156G,F157-,R158-,A222V,D253A,L452R,P681R,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.68 1329 219 16.5% 1 +[T19R,E156G,F157-,R158-,A222V,D253A,L452R,P681R,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.68 1329 53 4.0% 1 +[T19R,E156G,F157-,R158-,A222V,D253A,L452R,P681R,P809S,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.68 1329 33 2.5% 1 +[T19R,E156G,F157-,R158-,A222V,D253A,L452R,P681R,G885S,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.68 1329 31 2.3% 1 +[T19R,E156G,F157-,R158-,N211K,A222V,D253A,L452R,P681R,D950N,D979E]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.42.2 1328 872 65.7% 0 +[Q613H] (consensus) XBB.1.42.2 1328 61 4.6% 1 +[G181A,Q613H] XBB.1.42.2 1328 20 1.5% 1 +[H146K,Q613H]-[H146Q] XBB.1.42.2 1328 19 1.4% 1 +[M177I,Q613H] XBB.1.42.2 1328 14 1.1% 1 +[Q613H,T1117I] BN.1.3.6 1327 790 59.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.6 1327 41 3.1% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.6 1327 35 2.6% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.6 1327 33 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.6 1327 27 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V1122M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BQ.1.1.51 1326 870 65.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.51 1326 124 9.4% 1 +[H69-,V70-,W152R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.51 1326 55 4.1% 1 +[H69-,V70-,S98F,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.51 1326 30 2.3% 1 +[H69-,V70-,V213G,T250I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.51 1326 24 1.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.31 1326 962 72.5% 0 (consensus) XBB.1.5.31 1326 48 3.6% 1 +[M153V] XBB.1.5.31 1326 17 1.3% 1 +[H146K]-[H146Q] XBB.1.5.31 1326 17 1.3% 1 +[D1153Y] XBB.1.5.31 1326 14 1.1% 1 +[A701T] AY.7.2 1322 563 42.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.7.2 1322 393 29.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.2 1322 39 3.0% 1 +[V16F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.2 1322 21 1.6% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.7.2 1322 19 1.4% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,G1219C,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Q.2 1320 958 72.6% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.2 1320 58 4.4% 1 +[H69-,V70-,P272L,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.2 1320 50 3.8% 1 +[H69-,V70-,H245Y,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.2 1320 49 3.7% 2 +[A67V,H69-,V70-,A570D,T716I,I794T,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.2 1320 38 2.9% 1 +[H69-,V70-,A570D,T716I,I794T,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.177.54 1313 1080 82.3% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.54 1313 51 3.9% 1 +[L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.54 1313 19 1.4% 1 +[A222V,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.54 1313 18 1.4% 2 +[A222V,T859I,V860I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.54 1313 14 1.1% 1 +[A222V,S813I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.2.3 1312 873 66.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.3 1312 35 2.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N481K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.3 1312 33 2.5% 1 +[K147E,W152R,F157L,K187E,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.3 1312 27 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E1111Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.3 1312 20 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] AY.90 1304 881 67.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.90 1304 213 16.3% 1 +[T19R,E156G,F157-,R158-,P174S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.90 1304 26 2.0% 2 +[T19R,E156G,F157-,R158-,P174S,L452R,P681R,D950N,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.90 1304 23 1.8% 1 +[V16I,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.90 1304 16 1.2% 1 +[T19R,E156G,F157-,R158-,S256L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.61 1301 898 69.0% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.61 1301 120 9.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.61 1301 42 3.2% 1 +[T19R,P85S,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.61 1301 17 1.3% 2 +[T19R,P85S,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.61 1301 14 1.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,C1235F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.65 1299 456 35.1% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.65 1299 268 20.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.65 1299 59 4.5% 2 +[T19R,E156G,F157-,R158-,A222V,D228H,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.65 1299 51 3.9% 4 +[L5F,T19R,E156G,F157-,R158-,A222V,L452R,P681R,P809S,D950N,V1176F,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.65 1299 43 3.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.75.5 1299 752 57.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75.5 1299 56 4.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.5 1299 45 3.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,R346S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.5 1299 43 3.3% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F490V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.5 1299 24 1.8% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] AY.46.3 1292 573 44.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.3 1292 190 14.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.3 1292 115 8.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.3 1292 46 3.6% 1 +[T19R,W64C,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.3 1292 20 1.5% 2 +[T19R,W64C,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.291 1285 1122 87.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.291 1285 28 2.2% 1 +[Q52L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.291 1285 13 1.0% 1 +[Q580K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.291 1285 11 0.9% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.291 1285 11 0.9% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.369 1282 1051 82.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.369 1282 54 4.2% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.369 1282 30 2.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.369 1282 22 1.7% 2 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.369 1282 16 1.2% 1 +[T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.22 1273 1044 82.0% 0 +[F186S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.22 1273 113 8.9% 1 +[F186S,V213G,Y248H,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.22 1273 25 2.0% 1 +[F186S,V213G,G339D,Q493R,A924S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.22 1273 12 0.9% 1 +[F186S,V213G,G339D,Q493R,I1221V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.22 1273 5 0.4% 1 +[L5F,F186S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.4 1270 968 76.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.4 1270 19 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V687L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4 1270 11 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,K444R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4 1270 10 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L1141F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.4 1270 9 0.7% 1 +[T22N,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBB.1.5.72 1268 822 64.8% 0 +[F456L] (consensus) XBB.1.5.72 1268 25 2.0% 1 +[H146K,F456L]-[H146Q] XBB.1.5.72 1268 24 1.9% 1 +[F456L,P812S] XBB.1.5.72 1268 20 1.6% 1 +[F456L,G946R] XBB.1.5.72 1268 18 1.4% 1 +[F456L]-[R408S] GS.4.1 1266 872 68.9% 0 +[N185D,D253G,T478R,P521S]-[G252V,T478K] (consensus) GS.4.1 1266 35 2.8% 1 +[N185D,D253G,T478R,P521S,P561S]-[G252V,T478K] GS.4.1 1266 27 2.1% 1 +[N185D,D253G,T478R,P521S]-[T19I,G252V,T478K] GS.4.1 1266 23 1.8% 1 +[N185D,D253G,T478R,P521S,Q1201K]-[G252V,T478K] GS.4.1 1266 21 1.7% 1 +[N185D,D253G,T478R]-[G252V,T478K] BF.7.19 1259 907 72.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.19 1259 32 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1058Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.19 1259 18 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.19 1259 15 1.2% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.19 1259 14 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.12.2 1255 1152 91.8% 0 +[V213G,G339D,R357K,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.12.2 1255 12 1.0% 2 +[V213G,G339D,R357K,Q493R,S704L,N1187D,C1236F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.2 1255 10 0.8% 1 +[V213G,G339D,R357K,Q493R,S704L,A783V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.2 1255 6 0.5% 1 +[V213G,G339D,R357K,Q493R,S704L,K1255R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.12.2 1255 5 0.4% 1 +[V213G,S255F,G339D,R357K,Q493R,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.20 1254 1085 86.5% 0 +[N148T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.20 1254 44 3.5% 1 +[I68T,N148T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.20 1254 21 1.7% 1 +[N148T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.20 1254 8 0.6% 1 +[N148T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.20 1254 6 0.5% 1 +[N148T,V213G,G339D,Q493R,S929T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.349 1253 816 65.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.349 1253 103 8.2% 1 +[E554D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.349 1253 83 6.6% 1 +[T22N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.349 1253 24 1.9% 1 +[E156V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.349 1253 20 1.6% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.16 1246 815 65.4% 0 (consensus) XBB.1.5.16 1246 41 3.3% 1 +[S704L] XBB.1.5.16 1246 30 2.4% 1 +[F456L] XBB.1.5.16 1246 23 1.8% 1 +[E661D] XBB.1.5.16 1246 23 1.8% 1 +[H146K]-[H146Q] BQ.1.1.70 1243 1006 80.9% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.70 1243 15 1.2% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.70 1243 15 1.2% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.70 1243 12 1.0% 1 +[T19L,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.70 1243 11 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.1.63 1242 845 68.0% 0 +[S12F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.63 1242 39 3.1% 1 +[S12F,N148T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.63 1242 24 1.9% 1 +[S12F,E654K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.63 1242 24 1.9% 2 +[S12F,N148T,L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.63 1242 21 1.7% 1 +[S12F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.31 1242 931 75.0% 0 +[H69-,V70-,L84I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.31 1242 73 5.9% 1 +[H69-,V70-,L84I,K182N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.31 1242 70 5.6% 1 +[H69-,V70-,L84I,W152L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.31 1242 10 0.8% 1 +[H69-,V70-,L84I,V213G,G339D,L452R,F486V,T778I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.31 1242 6 0.5% 1 +[L5F,H69-,V70-,L84I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] C.36.3 1240 705 56.9% 0 +[S12F,H69-,V70-,W152R,R346S,L452R,Q677H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.36.3 1240 62 5.0% 1 +[S12F,H69-,V70-,W152R,R346S,L452R,Q677H,A899S,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3 1240 20 1.6% 1 +[S12F,S13I,H69-,V70-,W152R,R346S,L452R,Q677H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3 1240 17 1.4% 1 +[S12F,H69-,V70-,W152R,R346S,L452R,T547I,Q677H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.36.3 1240 15 1.2% 1 +[S12F,H69-,V70-,W152R,D253Y,R346S,L452R,Q677H,A899S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.33 1240 881 71.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.33 1240 69 5.6% 1 +[H69-,V70-,K147I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.33 1240 44 3.5% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.33 1240 14 1.1% 6 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.33 1240 13 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BQ.1.1.67 1240 863 69.6% 0 +[H69-,V70-,L176F,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.67 1240 52 4.2% 1 +[H69-,V70-,L176F,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.67 1240 30 2.4% 1 +[H69-,V70-,L176F,V213G,G339D,K444M,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.67 1240 26 2.1% 1 +[H69-,V70-,L176F,V213G,G339D,K444T,L452R,F486V,K1154R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.67 1240 20 1.6% 1 +[H69-,V70-,L176F,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] AY.64 1238 716 57.8% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.64 1238 272 22.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.64 1238 44 3.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,A701S,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.64 1238 15 1.2% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.64 1238 12 1.0% 2 +[T19R,E156G,F157-,R158-,F186L,A222V,T385I,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.2 1232 636 51.6% 0 +[T478R]-[T478K] (consensus) EG.2 1232 69 5.6% 2 +[T478R,Q613H,A852S]-[T478K] EG.2 1232 30 2.4% 1 +[T478R]-[K417N,T478K] EG.2 1232 23 1.9% 1 +[F186L,T478R]-[T478K] EG.2 1232 21 1.7% 1 +[N185S,T478R]-[T478K] BA.2.75.1 1231 648 52.6% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] (consensus) BA.2.75.1 1231 49 4.0% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.1 1231 39 3.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.2.75.1 1231 15 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.75.1 1231 15 1.2% 3 +[K147E,W152R,F157L,N185-,F186-,I210V,V213G,G257S,R346I,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P,F490S] BA.2.68 1227 1016 82.8% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.68 1227 25 2.0% 1 +[F157L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.68 1227 22 1.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.68 1227 17 1.4% 2 +[V213G,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.68 1227 9 0.7% 1 +[F157S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.157 1225 684 55.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.157 1225 160 13.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.157 1225 67 5.5% 2 +[S691P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.157 1225 63 5.1% 1 +[L585F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.157 1225 44 3.6% 1 +[V70A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.3 1219 731 60.0% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.3 1219 101 8.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.3 1219 65 5.3% 1 +[H69-,V70-,E180V,V213G,G339D,L452R,F486V,T547I,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.3 1219 34 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A1020S,C1250F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.3 1219 27 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,A570S,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.1 1216 1050 86.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.5.1 1216 16 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,K854R,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.1 1216 16 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.1 1216 14 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.5.1 1216 13 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.47 1214 944 77.8% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.47 1214 31 2.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.47 1214 30 2.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.47 1214 20 1.6% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.47 1214 6 0.5% 2 +[H69-,V70-,V213G,G339D,L452R,V483A,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.6 1212 985 81.3% 0 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.6 1212 17 1.4% 1 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.6 1212 16 1.3% 1 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.6 1212 13 1.1% 1 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V,R1107S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.6 1212 12 1.0% 1 +[H69-,V70-,G181A,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.4 1210 943 77.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.6.4 1210 37 3.1% 1 +[H69-,V70-,V213G,G339D,V445F,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.4 1210 11 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.4 1210 11 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,N658S,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.4 1210 11 0.9% 1 +[H69-,V70-,V213G,A264T,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.147 1208 1061 87.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.147 1208 43 3.6% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.147 1208 23 1.9% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.147 1208 8 0.7% 1 +[W152R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.147 1208 6 0.5% 2 +[A694V,V1230L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FU.2 1206 657 54.5% 0 +[E180V,T478R,T547I]-[T478K] (consensus) FU.2 1206 62 5.1% 1 +[E180V,T478R,T547I,E554K]-[T478K] FU.2 1206 48 4.0% 1 +[H146K,E180V,T478R,T547I]-[H146Q,T478K] FU.2 1206 33 2.7% 2 +[E180V,T478R,T547I,A668S,A845S]-[T478K] FU.2 1206 19 1.6% 1 +[E180V,V445S,T478R,T547I]-[V445P,T478K] B.1.177.77 1203 807 67.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.77 1203 223 18.5% 1 +[A222V,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.77 1203 26 2.2% 1 +[S98F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.77 1203 15 1.2% 1 +[A222V,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.77 1203 14 1.2% 2 +[G72E,A222V,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.67 1200 567 47.2% 0 +[T19R,E156G,F157-,R158-,A222V,A262S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.67 1200 182 15.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.67 1200 110 9.2% 1 +[T19R,E156G,F157-,R158-,A222V,A262S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.67 1200 67 5.6% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.67 1200 41 3.4% 2 +[T19R,E156G,F157-,R158-,A222V,A348S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.35 1200 816 68.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.35 1200 48 4.0% 1 +[G72R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.35 1200 22 1.8% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.35 1200 19 1.6% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.35 1200 19 1.6% 2 +[G769R,D1084G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.241 1199 561 46.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.241 1199 85 7.1% 1 +[V90F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.241 1199 62 5.2% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.241 1199 56 4.7% 3 +[V6I,D138Y,I197V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.241 1199 51 4.3% 2 +[Q677H,V1128I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.396 1195 862 72.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.396 1195 40 3.3% 1 +[Y612F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.396 1195 31 2.6% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.396 1195 16 1.3% 1 +[E1262D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.396 1195 14 1.2% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.87 1194 632 52.9% 0 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.87 1194 171 14.3% 1 +[A222V,A262S,P272L,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.87 1194 102 8.5% 1 +[T19K,A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.87 1194 54 4.5% 1 +[L5F,A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.87 1194 44 3.7% 2 +[L176F,A222V,A262S,P272L,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.16 1192 1045 87.7% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.16 1192 17 1.4% 1 +[A27V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.16 1192 16 1.3% 1 +[A222V,S659L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.16 1192 12 1.0% 1 +[M153T,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.16 1192 8 0.7% 1 +[L5F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.15.2 1188 910 76.6% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,V320I,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.15.2 1188 30 2.5% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,V320I,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.2 1188 19 1.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,V320I,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S] BA.1.15.2 1188 17 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.15.2 1188 15 1.3% 4 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,V320I,G339D,S371L,Q493R,G496S,T547K,Q628K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F486P,F490S,N764K] BQ.1.1.6 1186 712 60.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.6 1186 162 13.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.6 1186 50 4.2% 1 +[H69-,V70-,G184V,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.6 1186 34 2.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,K1154R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.6 1186 28 2.4% 1 +[H69-,V70-,V213G,T307I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.2 1181 721 61.0% 0 +[D253G,F486S]-[G252V,F486P] (consensus) XBB.2 1181 19 1.6% 1 +[H146K,D253G,F486S]-[H146Q,G252V,F486P] XBB.2 1181 15 1.3% 1 +[D253G,F486S]-[Y144-,G252V,F486P] XBB.2 1181 11 0.9% 1 +[D253G,F486S]-[G252V,K417N,F486P] XBB.2 1181 11 0.9% 1 +[D253G,F486S]-[G252V,R408S,F486P] BA.2.3.6 1179 1076 91.3% 0 +[V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.6 1179 17 1.4% 1 +[V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.6 1179 6 0.5% 1 +[L5F,V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.6 1179 6 0.5% 1 +[F2L,V213G,S255F,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.6 1179 5 0.4% 1 +[V213G,S255F,G339D,Q493R,P1263L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.36.1 1178 758 64.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.36.1 1178 165 14.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36.1 1178 37 3.1% 1 +[T19R,F92I,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36.1 1178 12 1.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.36.1 1178 12 1.0% 2 +[T19R,F92I,T95I,E156G,F157-,R158-,L452R,P681R,D950N,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564 1178 481 40.8% 0 +[E780Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.564 1178 356 30.2% 2 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564 1178 132 11.2% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564 1178 55 4.7% 1 +[A522S,E780Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.564 1178 50 4.2% 1 +[E780Q,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.1.6 1175 1024 87.1% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.6 1175 20 1.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.6 1175 20 1.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,P1079S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.6 1175 15 1.3% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.1.6 1175 8 0.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,A958S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.14 1173 866 73.8% 0 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.14 1173 190 16.2% 4 +[W64L,V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.14 1173 20 1.7% 1 +[W64L,V213G,G339D,N450D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.14 1173 10 0.9% 1 +[W64L,V213G,G339D,Q493R,V534L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.14 1173 9 0.8% 1 +[W64L,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.46.2 1171 324 27.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.2 1171 200 17.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.2 1171 76 6.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,P809S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.2 1171 71 6.1% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,P809S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.2 1171 51 4.4% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.4 1166 795 68.2% 0 +[T883I] (consensus) XBB.1.5.4 1166 22 1.9% 1 +[T883I]-[K417N] XBB.1.5.4 1166 18 1.5% 1 +[S704L,T883I] XBB.1.5.4 1166 17 1.5% 1 +[N164S,T883I] XBB.1.5.4 1166 15 1.3% 3 +[M177I,N185D,T478R,T883I]-[T478K] B.1.177.73 1166 653 56.0% 0 +[A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.73 1166 177 15.2% 1 +[L5F,A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.73 1166 72 6.2% 1 +[S98F,A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.73 1166 43 3.7% 1 +[T95I,A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.73 1166 13 1.1% 2 +[S98F,D215Y,A222V,Q1071L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.2 1163 617 53.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.34.2 1163 315 27.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.2 1163 21 1.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N,D1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.2 1163 16 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.34.2 1163 14 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q677H,P681R,T859I,D950N,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617 1161 403 34.7% 0 +[E154K,L452R,E484Q,P681R,Q1071H,H1101D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.617 1161 109 9.4% 3 +[E154K,V382L,L452R,E484Q,P681R,Q1071H,D1153Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617 1161 98 8.4% 1 +[E154K,Q218H,L452R,E484Q,P681R,Q1071H,H1101D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617 1161 50 4.3% 1 +[E154K,L452R,E484Q,P681R,Q1071H,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.617 1161 49 4.2% 1 +[L452R,E484Q,P681R,Q1071H,H1101D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CK.1 1157 601 51.9% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1 1157 111 9.6% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1 1157 47 4.1% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] CK.1 1157 31 2.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1 1157 20 1.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,D1118V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.139 1157 814 70.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.139 1157 80 6.9% 2 +[T941A,M1229L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.139 1157 37 3.2% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.139 1157 33 2.9% 1 +[G252D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.139 1157 22 1.9% 1 +[T618I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.32 1156 874 75.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.32 1156 85 7.4% 1 +[W64R,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.32 1156 51 4.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.32 1156 14 1.2% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.32 1156 6 0.5% 2 +[V213G,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] GK.1 1155 405 35.1% 0 +[L455F,F456L,S704L] (consensus) GK.1 1155 115 10.0% 2 +[L455F,F456L,A475V,E554K,S704L] GK.1 1155 56 4.8% 2 +[N185D,L455F,F456L,A475V,S704L] GK.1 1155 51 4.4% 1 +[L455F,F456L,A475V,S704L] GK.1 1155 50 4.3% 1 +[F186L,L455F,F456L,S704L] XBB 1155 503 43.5% 0 +[F486S]-[G252V,F486P] (consensus) XBB 1155 20 1.7% 1 +[H146K,F486S]-[H146Q,G252V,F486P] XBB 1155 18 1.6% 1 +[F486S]-[G252V,K417N,F486P] XBB 1155 16 1.4% 1 +[F486S]-[T19I,G252V,F486P] XBB 1155 15 1.3% 5 +[F486S]-[L24-,P25-,P26-,A27S,Y144-,G252V,F486P] AY.109 1154 431 37.3% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.109 1154 143 12.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.109 1154 139 12.0% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,H1058Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.109 1154 83 7.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,E484K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.109 1154 66 5.7% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,S698L,D950N,H1058Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.10.1 1150 824 71.7% 0 +[E554K] (consensus) FL.10.1 1150 24 2.1% 1 +[H146K,E554K]-[H146Q] FL.10.1 1150 13 1.1% 1 +[E554K,D936Y] FL.10.1 1150 12 1.0% 1 +[E554K,F1075L] FL.10.1 1150 11 1.0% 1 +[E554K,A1070S] B.1.1.50 1150 324 28.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.50 1150 87 7.6% 1 +[N481K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.50 1150 66 5.7% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.50 1150 58 5.0% 2 -[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.50 1150 47 4.1% 2 +[A67S,E96Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.1.2 1150 726 63.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.2 1150 57 5.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2 1150 28 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.2 1150 18 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.2 1150 15 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D936N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.4.15 1147 936 81.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.15 1147 119 10.4% 1 +[V16F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.15 1147 35 3.1% 1 +[T19R,T95I,E156G,F157-,R158-,S161F,L452R,P681R,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.15 1147 5 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.15 1147 5 0.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,A1078S,T1238A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.31 1147 616 53.7% 0 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.31 1147 265 23.1% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.31 1147 20 1.7% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V,I1232S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.31 1147 19 1.7% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,V483I,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.31 1147 14 1.2% 2 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.12 1144 524 45.8% 0 +[T323I] (consensus) XBB.1.5.12 1144 174 15.2% 1 XBB.1.5.12 1144 30 2.6% 1 +[T323I]-[K417N] XBB.1.5.12 1144 17 1.5% 1 +[H146K,T323I]-[H146Q] XBB.1.5.12 1144 12 1.0% 3 -[R408S,S477N] BA.5.10 1144 816 71.3% 0 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.10 1144 74 6.5% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.10 1144 21 1.8% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.10 1144 12 1.0% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V,E654K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.10 1144 11 1.0% 1 +[H69-,V70-,Y200C,V213G,A262S,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.46.1 1143 787 68.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.46.1 1143 82 7.2% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.1 1143 73 6.4% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.1 1143 25 2.2% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,D1127Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.46.1 1143 16 1.4% 1 +[T19R,P85L,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.4.7 1143 931 81.5% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.7 1143 19 1.7% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S,D1163N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.7 1143 17 1.5% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.7 1143 15 1.3% 1 +[L5F,H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.7 1143 15 1.3% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BE.2 1142 870 76.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.2 1142 40 3.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.2 1142 26 2.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.2 1142 18 1.6% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.2 1142 9 0.8% 1 +[H69-,V70-,V213G,T240I,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.26 1137 996 87.6% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.26 1137 34 3.0% 1 +[V213G,G339D,Q493R,G1267R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.26 1137 9 0.8% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.26 1137 9 0.8% 1 +[V213G,G339D,Q493R,C1236F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.26 1137 7 0.6% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.277 1132 505 44.6% 0 +[A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.277 1132 181 16.0% 1 +[A626S,E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.277 1132 122 10.8% 1 +[A626S,E1195Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.277 1132 97 8.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.277 1132 36 3.2% 1 +[H49Y,A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.8 1131 960 84.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.8 1131 18 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.2.8 1131 17 1.5% 1 +[H69-,V70-,E180G,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.8 1131 15 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.8 1131 7 0.6% 1 +[F59S,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.221.3 1130 872 77.2% 0 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.221.3 1130 70 6.2% 1 +[H49Y,S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.3 1130 64 5.7% 1 +[S98F,V1065L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.3 1130 51 4.5% 1 +[S98F,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.221.3 1130 24 2.1% 1 +[S98F,S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.15 1125 610 54.2% 0 +[F456L] (consensus) FL.15 1125 79 7.0% 1 +[Q14H,F456L] FL.15 1125 38 3.4% 1 +[F456L,R1014K] FL.15 1125 18 1.6% 2 +[H146K,I197V,F456L]-[H146Q] FL.15 1125 17 1.5% 1 +[F456L]-[K417N] B.1.1.348 1124 449 39.9% 0 +[G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.348 1124 133 11.8% 1 +[A879S,G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.348 1124 73 6.5% 2 +[R346K,G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.348 1124 68 6.0% 1 +[V289I,G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.348 1124 51 4.5% 1 +[A348S,G1167A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.15 1118 858 76.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.15 1118 43 3.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.15 1118 36 3.2% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S1252Y]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.15 1118 18 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.15 1118 12 1.1% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q675K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DV.1.1 1117 824 73.8% 0 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) DV.1.1 1117 31 2.8% 1 +[K147E,W152R,F157L,L176F,L179P,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.1.1 1117 22 2.0% 1 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.1.1 1117 17 1.5% 2 +[K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,A344T,K444T,L452R,F486S,A522S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] DV.1.1 1117 14 1.3% 1 +[N30S,K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] EG.5.1.8 1115 651 58.4% 0 +[Q52H,L455F,F456L] (consensus) EG.5.1.8 1115 49 4.4% 1 +[Q52H,T95I,L455F,F456L] EG.5.1.8 1115 38 3.4% 1 +[Q52H,H146K,L455F,F456L]-[H146Q] EG.5.1.8 1115 33 3.0% 1 +[Q52H,L455F,F456L,E654V] EG.5.1.8 1115 18 1.6% 2 +[Q52H,H146K,L455F,F456L,E654V]-[H146Q] XBB.1.5.18 1115 736 66.0% 0 (consensus) XBB.1.5.18 1115 47 4.2% 2 +[W152R,T478R]-[T478K] XBB.1.5.18 1115 19 1.7% 2 +[F456L,Q675K] XBB.1.5.18 1115 15 1.3% 1 +[H146K]-[H146Q] XBB.1.5.18 1115 15 1.3% 4 +[W152R,T478R,E554Q,D1184Y]-[T478K] B.1.1.416 1102 798 72.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.416 1102 24 2.2% 1 +[T95I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.416 1102 21 1.9% 1 +[P330S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.416 1102 14 1.3% 1 +[T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.416 1102 13 1.2% 2 +[E156D,T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.2.3.11 1100 526 47.8% 0 +[D253G,T478R,P521S]-[G252V,T478K] (consensus) XBB.2.3.11 1100 77 7.0% 1 +[N185D,D253G,T478R,P521S]-[G252V,T478K] XBB.2.3.11 1100 42 3.8% 1 +[D253G,T478R,P521S,T883I]-[G252V,T478K] XBB.2.3.11 1100 41 3.7% 1 +[D253G,T478R,P521S,A845S]-[G252V,T478K] XBB.2.3.11 1100 20 1.8% 1 +[L216F,D253G,T478R,P521S]-[G252V,T478K] BL.1 1091 700 64.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BL.1 1091 24 2.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V,S680F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BL.1 1091 22 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] BL.1 1091 18 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BL.1 1091 14 1.3% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,D574V]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.409 1089 879 80.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.409 1089 27 2.5% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.409 1089 13 1.2% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.409 1089 12 1.1% 1 +[H1088R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.409 1089 10 0.9% 1 +[T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.11 1087 755 69.5% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.11 1087 39 3.6% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.11 1087 23 2.1% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T883I,S939F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.11 1087 15 1.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,P322A,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.11 1087 10 0.9% 2 +[K147E,W152R,F157L,I210V,L212S,V213G,G257S,R408N,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] B.1.177.56 1082 813 75.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.56 1082 84 7.8% 1 +[A222V,P809L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.56 1082 25 2.3% 1 +[D138H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.56 1082 22 2.0% 1 +[A222V,S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.56 1082 16 1.5% 1 +[I119V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.426 1081 841 77.8% 0 +[D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.426 1081 38 3.5% 1 +[D253G,T719I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.426 1081 26 2.4% 2 +[D253G,A263T,V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.426 1081 24 2.2% 1 +[H49Y,D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.426 1081 19 1.8% 1 +[L5F,D253G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.329 1080 1052 97.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.329 1080 3 0.3% 1 +[A163V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.329 1080 3 0.3% 1 +[N17D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.329 1080 2 0.2% 1 +[L849F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.329 1080 2 0.2% 1 +[H69Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.52 1077 550 51.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.52 1077 226 21.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.52 1077 61 5.7% 2 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.52 1077 15 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.52 1077 15 1.4% 1 +[H69-,V70-,V213G,G339D,K417T,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] AY.99.1 1075 443 41.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.99.1 1075 226 21.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.1 1075 42 3.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.1 1075 29 2.7% 2 +[T19R,E156G,F157-,R158-,D427G,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.99.1 1075 19 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17.1 1073 1011 94.2% 0 +[L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.17.1 1073 12 1.1% 1 +[L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17.1 1073 6 0.6% 1 +[L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,A879S,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17.1 1073 5 0.5% 1 +[L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,T523N,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.17.1 1073 5 0.5% 1 +[V3A,L18F,T20N,P26S,H49Y,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.23 1073 872 81.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.23 1073 31 2.9% 1 +[V3I,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.23 1073 23 2.1% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.23 1073 18 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.23 1073 10 0.9% 2 +[H69-,V70-,V213G,T323I,G339D,L452R,F486V,A688V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.44 1071 614 57.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.44 1071 101 9.4% 2 +[H69-,V70-,N185D,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.44 1071 46 4.3% 3 +[H69-,V70-,N185D,V213G,G339D,L452R,F486V,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.44 1071 37 3.5% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.44 1071 31 2.9% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.35 1063 449 42.2% 0 +[N978S] (consensus) XBB.1.5.35 1063 174 16.4% 1 +[S98F,N978S] XBB.1.5.35 1063 72 6.8% 1 +[D198G,N978S] XBB.1.5.35 1063 50 4.7% 1 +[N978S]-[K417N] XBB.1.5.35 1063 18 1.7% 1 +[H146K,N978S]-[H146Q] HH.1 1062 793 74.7% 0 +[G184V,D253G,P521S]-[G252V] (consensus) HH.1 1062 28 2.6% 1 +[H146K,G184V,D253G,P521S]-[H146Q,G252V] HH.1 1062 17 1.6% 1 +[G184V,D253G,Q493L,P521S]-[G252V] HH.1 1062 11 1.0% 1 +[G184V,D253G,P521S]-[G252V,K417N] HH.1 1062 7 0.7% 1 +[G184V,D253G,P521S]-[Y144-,G252V] XBB.1.5.77 1060 578 54.5% 0 (consensus) XBB.1.5.77 1060 38 3.6% 1 +[H146K]-[H146Q] XBB.1.5.77 1060 15 1.4% 2 +[L84I,T588I] XBB.1.5.77 1060 13 1.2% 1 -[R408S] XBB.1.5.77 1060 13 1.2% 1 -[K417N] BF.7.24 1058 708 66.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.24 1058 58 5.5% 1 +[T19L,H69-,V70-,V213G,G339D,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.24 1058 48 4.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,L1197F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.24 1058 16 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S691P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.24 1058 14 1.3% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] CQ.2 1055 916 86.8% 0 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CQ.2 1055 18 1.7% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CQ.2 1055 15 1.4% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,N460K,F486P,F490S] CQ.2 1055 10 0.9% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,N460K,F486P,F490S] CQ.2 1055 7 0.7% 1 +[H69-,V70-,P209L,V213G,G339D,K444R,V445A,L452R,F486V,S940F]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.43.2 1053 597 56.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.2 1053 179 17.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.2 1053 106 10.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.2 1053 16 1.5% 1 +[T19R,E156G,F157-,R158-,L452R,E471Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.2 1053 8 0.8% 1 +[T19R,E156G,F157-,R158-,L452R,S477I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.10 1052 916 87.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.10 1052 18 1.7% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.10 1052 10 1.0% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.10 1052 9 0.9% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,S691P,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.10 1052 8 0.8% 2 +[A67V,H69-,V70-,T95I,V143-,Y145-,M177I,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,D1163G]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] B.1.177.15 1050 831 79.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.15 1050 38 3.6% 1 +[S12F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.15 1050 31 3.0% 1 +[A222V,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.15 1050 23 2.2% 1 +[A222V,A845S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.15 1050 21 2.0% 1 +[A222V,G1167F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AZ.2 1048 827 78.9% 0 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AZ.2 1048 36 3.4% 1 +[T95I,G252S,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.2 1048 19 1.8% 2 +[T95I,E484K,Q607K,D796H,S875A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.2 1048 19 1.8% 1 +[L5F,T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.2 1048 10 1.0% 2 +[T95I,G252S,E484K,S640F,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.509 1047 847 80.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.509 1047 23 2.2% 2 +[D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.509 1047 14 1.3% 1 +[S98F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.509 1047 11 1.1% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.509 1047 10 1.0% 1 +[T76I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.2.1 1043 791 75.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.2.1 1043 72 6.9% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2.1 1043 17 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V,D1139H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.2.1 1043 11 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.2.1 1043 7 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I666V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] XBB.1.5.11 1042 665 63.8% 0 (consensus) XBB.1.5.11 1042 35 3.4% 1 +[H146K]-[H146Q] XBB.1.5.11 1042 20 1.9% 1 +[S704L] XBB.1.5.11 1042 19 1.8% 1 +[T883I] XBB.1.5.11 1042 13 1.2% 1 -[K417N] B.1.1.372 1040 704 67.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.372 1040 192 18.5% 1 +[P26L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.372 1040 9 0.9% 2 +[P26L,T29I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.372 1040 7 0.7% 2 +[P26L,L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.372 1040 7 0.7% 1 +[T323I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GF.1 1036 769 74.2% 0 +[E748V] (consensus) GF.1 1036 30 2.9% 1 +[H146K,E748V]-[H146Q] GF.1 1036 26 2.5% 1 +[R408G,E748V]-[R408S] GF.1 1036 10 1.0% 1 +[E748V]-[K417N] GF.1 1036 8 0.8% 2 +[E748V]-[R408S,S477N] XBC.1.3 1035 709 68.5% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.3 1035 31 3.0% 1 +[P25S,E156G,F157-,R158-,Y170H,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.3 1035 22 2.1% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.3 1035 14 1.4% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,K444T,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.3 1035 13 1.3% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] B.1.177.8 1029 807 78.4% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.8 1029 134 13.0% 1 +[L18F,A222V,I794L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.8 1029 5 0.5% 2 +[L18F,A222V,I794L,G1085R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.8 1029 5 0.5% 1 +[L18F,A222V,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.8 1029 4 0.4% 1 +[L18F,A222V,S373L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.42 1028 874 85.0% 0 +[I68T,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.42 1028 28 2.7% 1 +[I68T,R78G,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.42 1028 17 1.7% 1 +[I68T,V213G,G339D,Q493R,M1229I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.42 1028 12 1.2% 1 +[I68T,V213G,G339D,Q493R,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.42 1028 7 0.7% 1 +[I68T,V213G,G339D,Q493R,T778A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EU.1.1 1025 771 75.2% 0 +[I410V,P521S] (consensus) EU.1.1 1025 20 2.0% 1 +[I410V,S494P,P521S] EU.1.1 1025 18 1.8% 1 +[I410V,P521S]-[K417N] EU.1.1 1025 17 1.7% 1 +[H146K,I410V,P521S]-[H146Q] EU.1.1 1025 15 1.5% 1 +[Q14K,I410V,P521S] P.1.4 1024 870 85.0% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.4 1024 24 2.3% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,R646H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.4 1024 9 0.9% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,V622F,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.4 1024 9 0.9% 1 +[L18F,T20N,P26S,D138Y,R190S,G257D,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.4 1024 8 0.8% 2 +[L18F,T20N,P26S,D138Y,R190S,A243-,L244-,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] BA.2.49 1023 486 47.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.49 1023 326 31.9% 1 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.49 1023 48 4.7% 1 +[V213G,G339D,Q493R,T732I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.49 1023 22 2.2% 2 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.49 1023 17 1.7% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.50 1021 934 91.5% 0 +[T19R,E156G,F157-,R158-,V308L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.50 1021 20 2.0% 1 +[T19R,E156G,F157-,R158-,V308L,L452R,P681R,D950N,V1228I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.50 1021 17 1.7% 1 +[T19R,E156G,F157-,R158-,V308L,L452R,P681R,D950N,G1124V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.50 1021 9 0.9% 1 +[T19R,E156G,F157-,R158-,V308L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.50 1021 3 0.3% 1 +[T19R,E156G,F157-,R158-,T250I,V308L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.51 1021 709 69.4% 0 (consensus) XBB.1.5.51 1021 68 6.7% 1 +[T478R]-[T478K] XBB.1.5.51 1021 23 2.3% 1 +[T29I] XBB.1.5.51 1021 21 2.1% 1 +[H146K]-[H146Q] XBB.1.5.51 1021 12 1.2% 1 -[K417N] BF.7.19.1 1021 885 86.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.19.1 1021 25 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.19.1 1021 18 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1104L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.19.1 1021 10 1.0% 1 +[H69-,V70-,V213G,L244S,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.19.1 1021 6 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,S813I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.15 1019 673 66.0% 0 +[V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.15 1019 113 11.1% 1 +[V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.15 1019 45 4.4% 1 +[V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.3.15 1019 24 2.4% 2 +[V213G,D215E,G339D,Q493R]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.15 1019 20 2.0% 1 +[F157S,V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.102 1017 496 48.8% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.102 1017 107 10.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102 1017 54 5.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102 1017 33 3.2% 1 +[T19R,T95I,E156G,F157-,R158-,M177I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.102 1017 27 2.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D936Y,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.22 1011 790 78.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.22 1011 20 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.22 1011 11 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,I1183V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.22 1011 10 1.0% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.22 1011 9 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S,P681H] BA.2.3.12 1010 837 82.9% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.12 1010 14 1.4% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.12 1010 11 1.1% 2 +[V213G,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.3.12 1010 10 1.0% 1 +[V213G,T286I,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.12 1010 9 0.9% 1 +[V213G,G339D,Q493R,I1225V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.588 1009 748 74.1% 0 +[T20I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.588 1009 28 2.8% 1 +[T20I,A626V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.588 1009 27 2.7% 1 +[T20I,I68L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.588 1009 24 2.4% 1 +[T20I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.588 1009 15 1.5% 1 +[T20I,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBC.1.6 1005 699 69.6% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1.6 1005 83 8.3% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,V445A,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6 1005 50 5.0% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,A899S]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6 1005 15 1.5% 1 +[P25S,E156G,F157-,R158-,G184V,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1.6 1005 12 1.2% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,L452R,N703I,P812T]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] B.1.177.65 1005 770 76.6% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.65 1005 169 16.8% 1 +[L18F,G181V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.65 1005 19 1.9% 2 +[L18F,G75S,G181V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.65 1005 12 1.2% 1 +[L5F,L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.65 1005 4 0.4% 1 +[L18F,A222V,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.17 1003 579 57.7% 0 +[L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.17 1003 213 21.2% 1 +[L5F,L176F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.17 1003 58 5.8% 2 +[A222V,A846S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.17 1003 33 3.3% 2 +[L176F,A222V,A1078S,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.17 1003 23 2.3% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.6.2 1003 778 77.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.6.2 1003 29 2.9% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.6.2 1003 15 1.5% 2 +[H69-,V70-,N211-,L212I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.2 1003 11 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.2 1003 10 1.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,C1247F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.73 1002 255 25.4% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.73 1002 247 24.7% 1 +[T19R,W152L,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.73 1002 179 17.9% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.73 1002 99 9.9% 1 +[T19R,E156G,F157-,R158-,I210V,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.73 1002 15 1.5% 2 +[T19R,E156G,F157-,R158-,I210V,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.21 1001 649 64.8% 0 (consensus) XBB.1.5.21 1001 27 2.7% 1 +[H146K]-[H146Q] XBB.1.5.21 1001 23 2.3% 2 -[R408S,S477N] XBB.1.5.21 1001 20 2.0% 1 -[N764K] XBB.1.5.21 1001 15 1.5% 1 +[A260S] BA.2.13.1 997 774 77.6% 0 +[V213G,G339D,L452M,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.13.1 997 57 5.7% 1 +[V213G,G339D,L452M,Q493R,A892V,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13.1 997 28 2.8% 1 +[V213G,P217S,G339D,L452M,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13.1 997 23 2.3% 1 +[V213G,G339D,L452M,Q493R,P812L,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.13.1 997 9 0.9% 1 +[L5F,V213G,G339D,L452M,Q493R,T941S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BQ.1.3 994 669 67.3% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.3 994 51 5.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,V1133A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3 994 44 4.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3 994 14 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619Q,T1120I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.3 994 12 1.2% 1 +[H69-,V70-,W152R,V213G,G339D,K444T,L452R,F486V,E619Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] B.1.422 988 871 88.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.422 988 27 2.7% 1 +[G184S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.422 988 17 1.7% 1 +[P384R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.422 988 10 1.0% 1 +[T1009S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.422 988 7 0.7% 1 +[G257S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.3 986 751 76.2% 0 (consensus) FL.3 986 32 3.2% 1 +[H1159R] FL.3 986 12 1.2% 1 -[K417N] FL.3 986 11 1.1% 1 +[H146K]-[H146Q] FL.3 986 8 0.8% 1 +[L5F] BA.2.52 982 647 65.9% 0 +[V213G,Y248S,+248GEN,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.52 982 137 14.0% 4 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.52 982 48 4.9% 1 +[V213G,Y248S,+248GEN,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.52 982 8 0.8% 5 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.52 982 8 0.8% 1 +[V213G,Y248S,+248GEN,G339D,Q493R,P1143L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] P.1.2 981 598 61.0% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.2 981 61 6.2% 1 +[L18F,T20N,P26S,D138Y,R190S,A262S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.2 981 31 3.2% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.2 981 19 1.9% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.2 981 17 1.7% 2 +[L18F,T20N,P26S,D138Y,R190S,A262S,K417T,E484K,Q675H,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.67 972 687 70.7% 0 (consensus) XBB.1.5.67 972 23 2.4% 1 +[H146K]-[H146Q] XBB.1.5.67 972 15 1.5% 1 +[G257S] XBB.1.5.67 972 14 1.4% 1 +[T573I] XBB.1.5.67 972 13 1.3% 1 +[V62L] BA.2.41 968 566 58.5% 0 +[+212T,+213GGG,G339D,Q493R,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.41 968 183 18.9% 5 +[V213G,G339D,Q493R,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.41 968 96 9.9% 6 +[V213G,G339D,Q493R,A942S,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.41 968 11 1.1% 1 +[+212T,+213GGG,G339D,Q493R,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.41 968 10 1.0% 1 +[+212T,+213GGG,G339D,Q493R,A688V,T1231S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.367 967 712 73.6% 0 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.367 967 100 10.3% 1 +[D80Y,V90F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.367 967 33 3.4% 1 +[D80Y,D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.367 967 9 0.9% 1 +[L5F,D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.367 967 6 0.6% 1 +[D80Y,I794V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.49 965 750 77.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.49 965 13 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I,D1146Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.49 965 12 1.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.49 965 10 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T883I,D936Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.49 965 8 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.48 964 365 37.9% 0 +[T19R,K77T,E156G,F157-,R158-,L452R,T547I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.48 964 151 15.7% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.48 964 102 10.6% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,T547I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.48 964 83 8.6% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,T547I,V622A,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.48 964 49 5.1% 2 +[T19R,K77T,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.75 961 224 23.3% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.75 961 168 17.5% 1 +[A222V,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.75 961 159 16.5% 1 +[A222V,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.75 961 107 11.1% 1 +[Y144F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.75 961 32 3.3% 1 +[A222V,M1237I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FE.1.2 958 407 42.5% 0 +[F456L] (consensus) FE.1.2 958 112 11.7% 1 +[F456L]-[R346T] FE.1.2 958 61 6.4% 2 +[F456L]-[R346T,K417N] FE.1.2 958 29 3.0% 1 +[H146K,F456L]-[H146Q] FE.1.2 958 15 1.6% 1 +[F456L]-[K417N] AY.122.3 957 899 93.9% 0 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.3 957 8 0.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.3 957 7 0.7% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.3 957 3 0.3% 1 +[T19R,N30H,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.3 957 3 0.3% 1 +[T19R,E156G,F157-,R158-,L452R,Q613H,P681R,A684V,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.216 956 523 54.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.216 956 23 2.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.216 956 17 1.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.216 956 16 1.7% 1 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.216 956 15 1.6% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.2.5 952 685 72.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.5 952 59 6.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,A520S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.5 952 20 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,F565I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.5 952 15 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,L452R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.5 952 10 1.1% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] CM.2 949 745 78.5% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] (consensus) CM.2 949 13 1.4% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,T478E,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,T478K,E484A,F486P,F490S] CM.2 949 11 1.2% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N448D,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.2 949 10 1.1% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CM.2 949 7 0.7% 1 +[K150I,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,E484A,F486P,F490S] CJ.1.3 946 730 77.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] (consensus) CJ.1.3 946 18 1.9% 1 +[R21T,K147E,W152R,F157L,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3 946 12 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3 946 10 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] CJ.1.3 946 9 1.0% 1 +[K147E,W152R,F157L,D178H,I210V,V213G,G257S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P] B.1.1.420 943 334 35.4% 0 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.420 943 175 18.6% 1 +[L18F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.420 943 72 7.6% 2 +[L18F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.420 943 47 5.0% 2 +[L18F,P26S,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.420 943 46 4.9% 1 +[L18F,H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.21 937 657 70.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.21 937 27 2.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.21 937 19 2.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.1.21 937 15 1.6% 1 +[H69-,V70-,K182R,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.21 937 13 1.4% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.35 937 510 54.4% 0 +[T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.35 937 106 11.3% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.35 937 78 8.3% 1 +[L5F,T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.35 937 62 6.6% 1 +[T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D808E,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.35 937 40 4.3% 2 +[L5F,T19R,K77T,E156G,F157-,R158-,L452R,E484Q,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.1 935 760 81.3% 0 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.1 935 60 6.4% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.1 935 35 3.7% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N,I1221V]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.1 935 6 0.6% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N,N969S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.1 935 5 0.5% 1 +[T19R,T95I,E156G,F157-,R158-,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.316 932 348 37.3% 0 +[Q677H,T732S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.316 932 301 32.3% 1 +[Q677H,T732S,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.316 932 48 5.2% 2 +[V213L,Q677H,T732S,E1202Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.316 932 28 3.0% 1 +[S94F,Q677H,T732S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.316 932 28 3.0% 1 +[T76I,Q677H,T732S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.95 930 544 58.5% 0 (consensus) XBB.1.5.95 930 30 3.2% 1 +[E725D] XBB.1.5.95 930 29 3.1% 1 -[K417N] XBB.1.5.95 930 20 2.2% 1 +[T51I] XBB.1.5.95 930 15 1.6% 1 +[L1265F] BG.2 930 847 91.1% 0 +[V213G,G339D,L452Q,Q493R,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BG.2 930 9 1.0% 1 +[V213G,G339D,L452Q,Q493R,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BG.2 930 7 0.8% 1 +[V213G,G339D,L452Q,Q493R,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BG.2 930 6 0.6% 1 +[L5F,V213G,G339D,L452Q,Q493R,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BG.2 930 5 0.5% 1 +[V213G,G339D,L452Q,Q493R,A522P,S704L,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.1 930 416 44.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.6.1 930 261 28.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.6.1 930 34 3.7% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.6.1 930 19 2.0% 2 +[H69-,V70-,K147I,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.5.6.1 930 18 1.9% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.52 929 612 65.9% 0 (consensus) XBB.1.5.52 929 32 3.4% 1 +[F456L] XBB.1.5.52 929 24 2.6% 2 +[L176F,T236S] XBB.1.5.52 929 18 1.9% 1 +[T236S] XBB.1.5.52 929 13 1.4% 1 +[H146K]-[H146Q] AY.43.3 929 507 54.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.3 929 170 18.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.3 929 42 4.5% 1 +[T19R,E156G,F157-,R158-,V367L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.3 929 25 2.7% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.3 929 14 1.5% 3 +[V6F,T19R,E156G,F157-,R158-,L452R,P681R,D950N,D1041N,G1046D]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.9 920 258 28.0% 0 +[F486S]-[F486P] XBB.1.9 920 176 19.1% 1 (consensus) XBB.1.9 920 29 3.2% 2 +[Q613H] XBB.1.9 920 28 3.0% 1 +[F486S,S813G]-[F486P] XBB.1.9 920 24 2.6% 3 +[L242I,V635I] XBB.1.5.59 915 526 57.5% 0 +[F456L] (consensus) XBB.1.5.59 915 72 7.9% 1 +[H146K,F456L]-[H146Q] XBB.1.5.59 915 24 2.6% 1 +[M177I,F456L] XBB.1.5.59 915 22 2.4% 1 +[F456L,V510I] XBB.1.5.59 915 14 1.5% 1 +[F456L]-[K417N] XBB.1.5.73 912 626 68.6% 0 (consensus) XBB.1.5.73 912 26 2.9% 1 +[F456L] XBB.1.5.73 912 19 2.1% 1 +[N1187S] XBB.1.5.73 912 11 1.2% 1 -[Q183E] XBB.1.5.73 912 10 1.1% 2 +[S514F,V687L] BA.2.47 908 715 78.7% 0 +[V213G,Y248H,G339D,Q493R,S1261Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.47 908 68 7.5% 2 +[V213G,Y248H,G339D,Q493R,A1020S,P1143S,S1261Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.47 908 57 6.3% 4 +[V213G,Y248H,G339D,Q493R,S1261Y]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.47 908 15 1.7% 1 +[V213G,Y248H,G339D,Q493R,S1261Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.47 908 6 0.7% 1 +[V213G,Y248H,G339D,Q493R,S1261Y]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] HK.6 906 589 65.0% 0 +[Q52H,D253G,F456L] (consensus) HK.6 906 33 3.6% 1 +[Q52H,R78M,D253G,F456L] HK.6 906 19 2.1% 1 +[Q52H,D253G,F456L,V1268I] HK.6 906 14 1.5% 1 +[Q52H,D253G,F456L,Q675H] HK.6 906 11 1.2% 1 +[Q52H,D253G,F456L]-[E484A] FE.1.1 906 635 70.1% 0 +[F456L] (consensus) FE.1.1 906 24 2.6% 1 +[H146K,F456L]-[H146Q] FE.1.1 906 10 1.1% 1 +[F456L,V1228A] FE.1.1 906 9 1.0% 1 +[F456L]-[R346T] FE.1.1 906 8 0.9% 1 +[L5F,F456L] BQ.1.1.24 905 637 70.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.24 905 78 8.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.24 905 61 6.7% 2 +[H69-,V70-,N185I,F186-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.24 905 6 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T1117I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.24 905 6 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,P479L,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.122.4 905 482 53.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.4 905 213 23.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.4 905 16 1.8% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.4 905 12 1.3% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.4 905 10 1.1% 3 +[T19R,H49Y,E156G,F157-,R158-,L452R,Q613H,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.6 904 578 63.9% 0 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.122.6 904 155 17.1% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.6 904 15 1.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.6 904 11 1.2% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,E780D,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.122.6 904 10 1.1% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N,D1259H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2.1 901 599 66.5% 0 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.120.2.1 901 130 14.4% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2.1 901 83 9.2% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1050I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2.1 901 12 1.3% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,A522S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.120.2.1 901 10 1.1% 1 +[T19R,H66Y,T95I,E156G,F157-,R158-,L452R,P681R,S810A,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.72 900 448 49.8% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.72 900 187 20.8% 1 +[T19R,E156G,F157-,R158-,F201L,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.72 900 79 8.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.72 900 12 1.3% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.72 900 9 1.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.126 899 689 76.6% 0 +[D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.126 899 37 4.1% 1 +[D215Y,A1078V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.126 899 31 3.4% 1 +[R78M,D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.126 899 29 3.2% 1 +[D215Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.126 899 13 1.4% 1 +[D215Y,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.5.2 899 601 66.9% 0 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.5.2 899 101 11.2% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,Q677H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.2 899 17 1.9% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,P561S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.2 899 15 1.7% 1 +[H69-,V70-,T76I,V90L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.5.2 899 11 1.2% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.14 894 716 80.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.14 894 16 1.8% 2 +[V213G,G339D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,Q498R] BA.2.3.14 894 15 1.7% 1 +[V213G,G339D,Q493R,T1273I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.14 894 11 1.2% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.14 894 9 1.0% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] AY.123 890 471 52.9% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.123 890 118 13.3% 1 +[T19R,T95I,E156G,F157-,R158-,A222V,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.123 890 70 7.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.123 890 35 3.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,Q1201H,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.123 890 19 2.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162S,P1263L]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.389 890 771 86.6% 0 +[T723I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.389 890 16 1.8% 1 +[T723I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.389 890 14 1.6% 1 +[T723I,E1202D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.389 890 9 1.0% 1 +[W258L,T723I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.389 890 5 0.6% 1 +[I472V,T723I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.10 888 658 74.1% 0 +[A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.10 888 46 5.2% 1 +[A222V,A262S,P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.10 888 21 2.4% 2 +[Q52R,A222V,A262S,A688V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.10 888 16 1.8% 1 +[A222V,A262S,H1083Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.10 888 11 1.2% 2 +[A222V,S254P,A262S,P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.63 886 602 67.9% 0 (consensus) XBB.1.5.63 886 35 4.0% 1 +[K1205R] XBB.1.5.63 886 20 2.3% 1 -[T19I] XBB.1.5.63 886 15 1.7% 1 +[H146K]-[H146Q] XBB.1.5.63 886 15 1.7% 1 +[T299I] BA.5.7 885 767 86.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.7 885 9 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.7 885 7 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.7 885 6 0.7% 2 +[V6I,H69-,V70-,V213G,G339D,L452R,Y453F,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.7 885 4 0.5% 1 +[H69-,V70-,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.25 883 729 82.6% 0 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.25 883 19 2.2% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.25 883 7 0.8% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V,S704L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.25 883 6 0.7% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,T478E,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,T478K,F486P,F490S] BF.25 883 6 0.7% 1 +[T19L,H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] FK.1.1 881 658 74.7% 0 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) FK.1.1 881 22 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1 881 22 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H,M1237I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1 881 15 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,K558R,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] FK.1.1 881 14 1.6% 1 +[K147E,W152L,F157L,I210V,V213G,D215G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.5.2.25 881 629 71.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.25 881 65 7.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.25 881 21 2.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.25 881 15 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.25 881 14 1.6% 1 +[H69-,V70-,V213G,G339D,T430I,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.22.1 879 258 29.4% 0 +[Y200C,T572I] XBB.1.22.1 879 215 24.5% 1 +[Y200C] (consensus) XBB.1.22.1 879 30 3.4% 1 +[A67S,Y200C,T572I] XBB.1.22.1 879 24 2.7% 2 XBB.1.22.1 879 23 2.6% 2 +[Y200C,Q675K] AY.51 879 208 23.7% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.51 879 182 20.7% 2 +[T19R,E156G,F157-,R158-,L452R,A520S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.51 879 171 19.5% 1 +[T19R,E156G,F157-,R158-,L452R,A520S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.51 879 95 10.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.51 879 16 1.8% 3 +[T19R,E156G,F157-,R158-,L452R,A520S,P681R,D950N,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CK.2.1 879 405 46.1% 0 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.2.1 879 223 25.4% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1 879 24 2.7% 1 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1 879 16 1.8% 1 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] CK.2.1 879 14 1.6% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.5.1.4 879 735 83.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.4 879 11 1.3% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.4 879 9 1.0% 1 +[H69-,V70-,L212S,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.4 879 9 1.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.4 879 8 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BQ.1.6 875 557 63.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.6 875 66 7.5% 1 +[H69-,V70-,V213G,D215H,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.6 875 36 4.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,I1130M]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.6 875 33 3.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q1142R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.6 875 20 2.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,F855L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] AY.16 872 337 38.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.16 872 128 14.7% 2 +[T19R,E156G,F157-,R158-,D215H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.16 872 99 11.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.16 872 33 3.8% 1 +[T19R,E156G,F157-,R158-,S255F,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.16 872 27 3.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.3 870 590 67.8% 0 +[T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.3.3 870 91 10.5% 1 +[T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.3 870 46 5.3% 1 +[T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N,D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.3 870 24 2.8% 1 +[L5F,T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.3.3 870 8 0.9% 2 +[T19R,V70I,E156G,F157-,R158-,Q414R,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.3.1 869 573 65.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] (consensus) BN.3.1 869 40 4.6% 2 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S,K356T,N450D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.3.1 869 17 2.0% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,R408S,V445P,F486P] BN.3.1 869 13 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.3.1 869 13 1.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,N450D,N1187T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] FY.2 868 598 68.9% 0 +[I197T,Y200C] (consensus) FY.2 868 36 4.1% 1 +[I197T,Y200C,V1264L] FY.2 868 24 2.8% 1 +[I197T,Y200C,I210-] FY.2 868 17 2.0% 1 +[H146K,I197T,Y200C]-[H146Q] FY.2 868 14 1.6% 1 +[Q173K,I197T,Y200C] P.1.12 868 467 53.8% 0 +[L18F,T20N,P26S,D138Y,R190S,R246G,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.12 868 246 28.3% 2 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.12 868 27 3.1% 1 +[L18F,T20N,P26S,D138Y,R190S,R246G,K417T,E484K,T961M,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] P.1.12 868 11 1.3% 3 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,N536S,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.12 868 7 0.8% 4 +[L5F,L18F,T20N,P26S,D138Y,K150R,R190S,R246G,K417T,E484K,T547I,G769K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.33 868 678 78.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.33 868 30 3.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.33 868 13 1.5% 1 +[Q14H,H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.33 868 11 1.3% 2 +[H69-,V70-,V213G,G339D,L452R,F486V,V1264L]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.33 868 11 1.3% 1 +[H69-,V70-,V213G,S255F,G339D,L452R,F486V,V1264L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.86.1 867 540 62.3% 0 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] (consensus) BA.2.86.1 867 87 10.0% 4 +[R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.1 867 21 2.4% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,L455S,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.1 867 18 2.1% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,P621S,P681R,S939F,V1104L,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] BA.2.86.1 867 8 0.9% 1 +[+16MPLF,R21T,S50L,H69-,V70-,V127F,F157S,R158G,N211-,L212I,V213G,L216F,H245N,A264D,I332V,K356T,R403K,V445H,N450D,L452W,N481K,V483-,E484K,E554K,A570V,T572I,P621S,P681R,S939F,P1143L]-[V83A,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,E484A,F490S,P681H] B.1.1.207 858 404 47.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.207 858 282 32.9% 1 +[E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.207 858 12 1.4% 2 +[P85S,E484K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.207 858 8 0.9% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.207 858 7 0.8% 1 +[L922F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] XBB.1.5.2 854 576 67.4% 0 +[K147I,T284I] (consensus) XBB.1.5.2 854 59 6.9% 1 +[T284I] XBB.1.5.2 854 24 2.8% 1 +[K147I,V213D,T284I]-[V213E] XBB.1.5.2 854 14 1.6% 1 +[K147I,T284I,K558N] XBB.1.5.2 854 13 1.5% 1 +[K147I,T284I,S494P] BA.2.11 854 667 78.1% 0 +[V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.11 854 47 5.5% 1 +[V213G,G339D,L452R,Q493R,D1259H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.11 854 19 2.2% 1 +[V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.11 854 18 2.1% 1 +[V213G,G339D,L452R,Q493R,L938F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.11 854 13 1.5% 1 +[F157L,V213G,G339D,L452R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BY.1 847 510 60.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BY.1 847 19 2.2% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1 847 17 2.0% 1 +[K147E,W152R,F157L,I210V,N211T,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1 847 14 1.7% 2 +[K147E,W152R,F157L,I210V,N211T,V213G,G257S,F486S,A522S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BY.1 847 14 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452Q,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] AY.8 846 765 90.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.8 846 15 1.8% 1 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.8 846 12 1.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,G1251R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.8 846 7 0.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.8 846 4 0.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,S813I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BW.1.1 845 666 78.8% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BW.1.1 845 22 2.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BW.1.1 845 9 1.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,P621S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1.1 845 8 0.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BW.1.1 845 6 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486A,V635I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.1.35 842 637 75.7% 0 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.35 842 33 3.9% 1 +[L5F,H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.35 842 13 1.5% 1 +[H69-,V70-,K147E,V213G,T284I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.35 842 13 1.5% 2 +[H69-,V70-,K147E,V213G,G339D,K444T,L452R,F486V,T547K,V687I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.35 842 13 1.5% 1 +[H69-,V70-,K147E,V213G,G339D,I358V,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.47 840 491 58.5% 0 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.47 840 51 6.1% 2 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V,T523N,D1165N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.47 840 33 3.9% 1 +[H69-,V70-,K147I,W152L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.47 840 16 1.9% 1 +[H69-,V70-,K147I,V213G,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.47 840 12 1.4% 1 +[H69-,V70-,K147I,W152R,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] A.23.1 837 268 32.0% 0 +[F157L,V367F,Q613H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.23.1 837 213 25.4% 1 +[R102I,F157L,V367F,Q613H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23.1 837 50 6.0% 1 +[F157L,V367F,Q613H,P681R,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23.1 837 49 5.9% 2 +[R102I,F157L,V367F,E484K,Q613H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.23.1 837 34 4.1% 1 +[L141F,F157L,V367F,Q613H,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.12 836 714 85.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.12 836 24 2.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.12 836 6 0.7% 1 +[H69-,V70-,T95I,V213G,G339D,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.12 836 5 0.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486I]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.12 836 5 0.6% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.6.6 835 710 85.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6.6 835 17 2.0% 1 +[D1118V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.6 835 9 1.1% 1 +[S1249Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.6 835 8 1.0% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6.6 835 5 0.6% 1 +[F490L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.8 833 195 23.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.8 833 105 12.6% 1 +[V227L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.8 833 95 11.4% 2 +[M153I,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.8 833 35 4.2% 1 +[L54F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.8 833 34 4.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.153 832 580 69.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.153 832 39 4.7% 1 +[T1120I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.153 832 33 4.0% 1 +[F157L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.153 832 17 2.0% 1 +[L176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.153 832 15 1.8% 1 +[H625Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.16 831 706 85.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.16 831 19 2.3% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.16 831 13 1.6% 2 +[T1027I,T1117I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.16 831 7 0.8% 1 +[D1163Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.16 831 5 0.6% 1 +[S255F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619 830 525 63.3% 0 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.619 830 53 6.4% 1 +[I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619 830 51 6.1% 1 +[I210T,E484K,A879S,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619 830 34 4.1% 1 +[L5F,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.619 830 14 1.7% 1 +[I128V,I210T,E484K,D936N,S939F,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.371 827 745 90.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.371 827 15 1.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.371 827 14 1.7% 1 +[L922F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.371 827 14 1.7% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.371 827 7 0.8% 1 +[S929I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.84 825 340 41.2% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.84 825 275 33.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.84 825 29 3.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.84 825 13 1.6% 2 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.84 825 11 1.3% 2 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.1 824 473 57.4% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.1 824 120 14.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.1 824 80 9.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.1 824 33 4.0% 1 +[T19R,S98F,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.1 824 7 0.8% 2 +[T19R,S98F,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.46 824 539 65.4% 0 (consensus) XBB.1.5.46 824 36 4.4% 2 -[R408S,S477N] XBB.1.5.46 824 27 3.3% 1 +[H146K]-[H146Q] XBB.1.5.46 824 21 2.5% 1 -[K417N] XBB.1.5.46 824 16 1.9% 1 +[L5F] GN.1 823 503 61.1% 0 +[F456L] (consensus) GN.1 823 40 4.9% 1 +[F456L,T747I] GN.1 823 37 4.5% 1 +[H146K,F456L]-[H146Q] GN.1 823 36 4.4% 1 +[G181V,F456L] GN.1 823 16 1.9% 1 +[F456L]-[R408S] FU.2.1 820 684 83.4% 0 +[E180V,T478R,T547I,E619Q]-[T478K] (consensus) FU.2.1 820 9 1.1% 1 +[E180V,Y351F,T478R,T547I,E619Q]-[T478K] FU.2.1 820 7 0.9% 1 +[H146K,E180V,T478R,T547I,E619Q]-[H146Q,T478K] FU.2.1 820 5 0.6% 1 +[F157L,E180V,T478R,T547I,E619Q]-[T478K] FU.2.1 820 5 0.6% 1 +[L176F,E180V,T478R,T547I,E619Q]-[T478K] BF.11.1 818 553 67.6% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.11.1 818 52 6.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.1 818 28 3.4% 1 +[Q14R,H69-,V70-,V213G,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.1 818 24 2.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.1 818 9 1.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1124V,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.464 815 712 87.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.464 815 11 1.3% 1 +[L822F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.464 815 9 1.1% 1 +[L1244F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.464 815 7 0.9% 1 +[M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.464 815 6 0.7% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.24 814 486 59.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.24 814 31 3.8% 2 +[S71P,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q1180K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.24 814 30 3.7% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T572I,D1184N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.24 814 26 3.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.24 814 15 1.8% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] HK.3.2 812 446 54.9% 0 +[Q14K,Q52H,L455F,F456L] (consensus) HK.3.2 812 130 16.0% 1 +[Q14K,Q52H,L455F,F456L,Q677H] HK.3.2 812 24 3.0% 1 +[Q14K,Q52H,N185D,L455F,F456L] HK.3.2 812 16 2.0% 2 +[Q14K,A27-,Q52H,L455F,F456L]-[L24-,A27S] HK.3.2 812 15 1.8% 2 +[Q14K,Q52H,R214H,L455F,F456L,I1221T] AY.80 808 334 41.3% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.80 808 272 33.7% 1 +[T19R,T20I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.80 808 100 12.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.80 808 28 3.5% 1 +[T19R,R21T,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.80 808 16 2.0% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A701S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EJ.2 807 611 75.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) EJ.2 807 14 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H,D1260E]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.2 807 13 1.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] EJ.2 807 11 1.4% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] EJ.2 807 9 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,T250A,G257S,K356T,D1139H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] XBB.1.5.19 804 518 64.4% 0 (consensus) XBB.1.5.19 804 40 5.0% 1 +[A411S] XBB.1.5.19 804 26 3.2% 1 +[F59L] XBB.1.5.19 804 19 2.4% 1 +[S98F] XBB.1.5.19 804 16 2.0% 1 +[N856S] B.1.499 804 431 53.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.499 804 78 9.7% 1 +[E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.499 804 57 7.1% 1 +[A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.499 804 16 2.0% 2 +[A626S,P1162L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.499 804 15 1.9% 1 +[G181A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BU.1 801 614 76.7% 0 +[H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BU.1 801 51 6.4% 1 +[H69-,V70-,V213G,S255F,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BU.1 801 15 1.9% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,F486P,F490S] BU.1 801 14 1.7% 1 +[L5F,H69-,V70-,V213G,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BU.1 801 10 1.2% 1 +[H69-,V70-,V213G,G252D,G339D,K444M,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1.1 801 578 72.2% 0 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.2.1.1 801 28 3.5% 1 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1.1 801 17 2.1% 1 +[H69-,V70-,V213G,S255F,T323I,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1.1 801 14 1.7% 1 +[H69-,V70-,V213G,T250I,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.2.1.1 801 10 1.2% 1 +[H69-,V70-,V213G,S255F,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] B.1.177.42 801 714 89.1% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.42 801 35 4.4% 1 +[P26H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.42 801 9 1.1% 1 +[F140L,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.42 801 6 0.7% 1 +[A222V,T553I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.42 801 4 0.5% 1 +[L216F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.436 800 748 93.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.436 800 11 1.4% 1 +[G75V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.436 800 8 1.0% 1 +[K537R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.436 800 3 0.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.436 800 3 0.4% 1 +[P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.27 797 496 62.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.27 797 162 20.3% 1 +[A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.27 797 33 4.1% 1 +[T470N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.27 797 29 3.6% 1 +[V213M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.27 797 16 2.0% 2 +[D936G,A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.354 796 433 54.4% 0 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.354 796 36 4.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.354 796 25 3.1% 2 +[S12F,D138Y,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.354 796 22 2.8% 1 +[D138Y,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.354 796 18 2.3% 1 +[H66R,D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.320 792 445 56.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.320 792 145 18.3% 1 +[V6F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.320 792 72 9.1% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.320 792 46 5.8% 1 +[S221L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.320 792 4 0.5% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.206 791 667 84.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.206 791 17 2.1% 2 +[A701V,D1260Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.206 791 13 1.6% 1 +[R1107S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.206 791 6 0.8% 1 +[A27V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.206 791 5 0.6% 1 +[S640F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.5.2 790 398 50.4% 0 +[F456L] (consensus) EG.5.2 790 93 11.8% 2 +[H69-,V70-,F456L] EG.5.2 790 40 5.1% 1 +[F456L,A845S] EG.5.2 790 26 3.3% 2 +[H146K,F456L,A845S]-[H146Q] EG.5.2 790 15 1.9% 1 +[H146K,F456L]-[H146Q] BQ.1.25.1 790 641 81.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.25.1 790 13 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,M731I,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25.1 790 12 1.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L858I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25.1 790 11 1.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,R646H,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.25.1 790 6 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,L858I,K1045R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.1.12 789 681 86.3% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.12 789 14 1.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,R1185H]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.12 789 13 1.6% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.12 789 11 1.4% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S,N764K] BA.1.12 789 6 0.8% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,E309Q,G339D,S371L,Q493R,G496S,T547K,N856K,L981F,Q1113L]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BF.7.7 787 662 84.1% 0 +[H69-,V70-,D80G,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.7 787 19 2.4% 1 +[H69-,V70-,D80G,V213G,G339D,L452R,F486V,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.7 787 9 1.1% 1 +[H69-,V70-,D80G,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.7.7 787 7 0.9% 1 +[H69-,V70-,D80G,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.7 787 5 0.6% 1 +[F2L,H69-,V70-,D80G,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.24 787 458 58.2% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.24 787 37 4.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.24 787 22 2.8% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,L841F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.24 787 17 2.2% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V,D574N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.24 787 15 1.9% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] B.1.265 786 399 50.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.265 786 94 12.0% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.265 786 41 5.2% 1 +[D1118Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.265 786 38 4.8% 1 +[V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.265 786 35 4.5% 2 +[P26L,Q314K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] ED.2 785 500 63.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) ED.2 785 63 8.0% 1 +[H69-,V70-,G181V,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.2 785 56 7.1% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.2 785 21 2.7% 1 +[H69-,V70-,V213G,S256L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] ED.2 785 12 1.5% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] CM.8.1 782 493 63.0% 0 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] (consensus) CM.8.1 782 30 3.8% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,R403K,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1 782 10 1.3% 1 +[M153T,N164K,G181E,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1 782 8 1.0% 1 +[M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S,D1118Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CM.8.1 782 8 1.0% 1 +[T29I,M153T,N164K,V213G,H245N,G257D,G339D,K444R,N450D,L452M,E484R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,E484A,F486P,F490S] CP.1 782 564 72.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CP.1 782 61 7.8% 1 +[P9L,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.1 782 14 1.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] CP.1 782 12 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CP.1 782 12 1.5% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AZ.1 779 636 81.6% 0 +[T95I,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) AZ.1 779 89 11.4% 1 +[T95I,A222V,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.1 779 9 1.2% 1 +[T95I,E180D,E484K,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.1 779 5 0.6% 1 +[T95I,E484K,T678I,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AZ.1 779 5 0.6% 1 +[T95I,E484K,S680F,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] DT.2 776 684 88.1% 0 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DT.2 776 7 0.9% 1 +[L5F,H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.2 776 6 0.8% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K,G1124D]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.2 776 5 0.6% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DT.2 776 4 0.5% 1 +[H69-,V70-,M153I,V213G,G339D,K444T,L452R,F486V,T547K,V1230M]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] XBB.1.5.66 774 511 66.0% 0 (consensus) XBB.1.5.66 774 17 2.2% 1 +[T478R]-[T478K] XBB.1.5.66 774 13 1.7% 1 -[K417N] XBB.1.5.66 774 10 1.3% 1 +[H146K]-[H146Q] XBB.1.5.66 774 9 1.2% 1 +[T208M] DF.1 773 568 73.5% 0 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) DF.1 773 36 4.7% 1 +[H69-,V70-,F157L,V213G,A262S,G339D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DF.1 773 21 2.7% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V,P1263R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DF.1 773 14 1.8% 1 +[H69-,V70-,V213G,A262S,G339D,L452R,F486V,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] DF.1 773 12 1.6% 2 +[H69-,V70-,V213G,A262S,G339D,G446V,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.3 771 712 92.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.3 771 21 2.7% 1 +[S254F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3 771 5 0.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3 771 3 0.4% 1 +[A879T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3 771 3 0.4% 1 +[W64L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2 770 552 71.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) A.2 770 53 6.9% 1 +[I197V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2 770 25 3.2% 1 +[Q675R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2 770 14 1.8% 9 +[L141-,G142-,V143-,D215A,+215AGY,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] A.2 770 9 1.2% 5 +[L141-,G142-,V143-,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.16.9 767 505 65.8% 0 +[E180V,F456L,T478R]-[T478K] (consensus) XBB.1.16.9 767 54 7.0% 1 +[E180V,F456L,T478R,S494P]-[T478K] XBB.1.16.9 767 16 2.1% 1 +[E180V,A344S,F456L,T478R]-[T478K] XBB.1.16.9 767 16 2.1% 1 +[E180V,F456L,T478R,K529N]-[T478K] XBB.1.16.9 767 15 2.0% 1 +[E180V,S256L,F456L,T478R]-[T478K] FL.10 765 454 59.3% 0 (consensus) FL.10 765 24 3.1% 1 +[T51I] FL.10 765 19 2.5% 1 -[R408S] FL.10 765 15 2.0% 2 +[K356T,T523N] FL.10 765 14 1.8% 1 -[G142D] EG.1.2 763 580 76.0% 0 +[Q613H] (consensus) EG.1.2 763 25 3.3% 1 +[P479R,Q613H] EG.1.2 763 16 2.1% 1 +[Q613H,P1162S] EG.1.2 763 8 1.0% 1 +[Q613H,E654D] EG.1.2 763 7 0.9% 1 +[P85L,Q613H] B.1.36.1 763 288 37.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.1 763 212 27.8% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.1 763 34 4.5% 1 +[A520S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.1 763 25 3.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.36.1 763 16 2.1% 1 +[Q779L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.13 763 505 66.2% 0 +[T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.13 763 48 6.3% 1 +[T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.13 763 31 4.1% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.13 763 17 2.2% 1 +[T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,D950N,D1165Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.13 763 15 2.0% 1 +[T19R,T95I,E156G,F157-,R158-,V213A,L452R,P681R,S937T,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.1.4 761 511 67.1% 0 +[Q613H] (consensus) EG.1.4 761 16 2.1% 1 +[D215H,Q613H] EG.1.4 761 15 2.0% 1 +[Q613H]-[R408S] EG.1.4 761 14 1.8% 1 +[H146K,Q613H]-[H146Q] EG.1.4 761 12 1.6% 1 +[M177T,Q613H] B.1.375 755 489 64.8% 0 +[H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.375 755 86 11.4% 1 +[H69-,V70-,C1236S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.375 755 70 9.3% 1 +[H69-,V70-,S477R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.375 755 14 1.9% 1 +[H69-,V70-,V622I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.375 755 6 0.8% 1 +[H49Y,H69-,V70-]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.23.1 753 655 87.0% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.23.1 753 23 3.1% 1 +[V213G,G257D,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23.1 753 10 1.3% 4 +[V213G,G339D,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.23.1 753 8 1.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.23.1 753 6 0.8% 1 +[L5F,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.551 752 256 34.0% 0 +[P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.551 752 213 28.3% 2 +[S254F,P681R,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.551 752 86 11.4% 1 +[S98F,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.551 752 50 6.6% 1 +[T95A,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.551 752 14 1.9% 3 +[S254F,P681R,T747I,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.3.10 752 673 89.5% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.10 752 8 1.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.3.10 752 8 1.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.10 752 6 0.8% 1 +[V213G,G339D,Q493R,P1143S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.10 752 6 0.8% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.239 747 344 46.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.239 747 128 17.1% 2 +[L18F,P251H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.239 747 38 5.1% 1 +[R237S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.239 747 30 4.0% 1 +[D178N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.239 747 17 2.3% 1 +[I233V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.568 747 594 79.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.568 747 19 2.5% 1 +[P561S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.568 747 9 1.2% 1 +[K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.568 747 8 1.1% 1 +[T22I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.568 747 8 1.1% 1 +[D80N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.13 744 427 57.4% 0 (consensus) FL.13 744 50 6.7% 4 +[Q14H,K182E,F456L,E484K]-[E484A] FL.13 744 23 3.1% 1 -[K417N] FL.13 744 22 3.0% 1 +[F456L] FL.13 744 8 1.1% 1 +[L5F] BA.2.3.4 744 684 91.9% 0 +[V213G,G339D,Q493R,N641S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.4 744 9 1.2% 1 +[V213G,G339D,Q493R,N641S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.3.4 744 4 0.5% 1 +[V213G,G339D,Q493R,N641S,S943G]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.4 744 4 0.5% 1 +[V213G,G339D,Q493R,N641S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.3.4 744 4 0.5% 1 +[V213G,G339D,K444R,Q493R,N641S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.24 741 663 89.5% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.24 741 32 4.3% 1 +[R214L,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.24 741 7 0.9% 1 +[A222V,E1262A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.24 741 4 0.5% 1 +[H69Y,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.24 741 4 0.5% 1 +[A222V,C1250F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.14.1 739 363 49.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14.1 739 209 28.3% 1 +[H69-,V70-,V83F,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.1 739 10 1.4% 2 +[H69-,V70-,V83F,V213G,G339D,L452R,F486V,T739A,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.1 739 8 1.1% 3 +[H69-,V70-,V83F,V213G,E309Q,G339D,L452R,F486V,N1187S,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.1 739 6 0.8% 1 +[H69-,V70-,G75V,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.2 739 547 74.0% 0 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.11.2 739 59 8.0% 1 +[H69-,V70-,T76I,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.2 739 26 3.5% 1 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V,I598V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.2 739 24 3.2% 1 +[L5F,H69-,V70-,K147N,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.11.2 739 6 0.8% 1 +[H69-,V70-,K147N,V213G,G339D,L452R,F486V,T883I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.351.2 737 387 52.5% 0 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.351.2 737 53 7.2% 1 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V,I934V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.2 737 25 3.4% 1 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V,I1232F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.2 737 19 2.6% 2 +[L18F,G75V,D80A,D215G,L242-,A243-,L244-,E484K,A701V,I934V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.2 737 15 2.0% 1 +[L18F,D80A,E180G,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.346 734 617 84.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.346 734 17 2.3% 1 +[P812L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.346 734 8 1.1% 2 +[D287G,V1122L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.346 734 8 1.1% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.346 734 7 1.0% 1 +[I569F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.10 733 558 76.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.10 733 21 2.9% 2 +[S221L,T250A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.10 733 19 2.6% 1 +[M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.10 733 17 2.3% 1 +[A879S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.10 733 7 1.0% 3 +[H69-,V70-,S221L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.18.1 732 223 30.5% 0 (consensus) XBB.1.18.1 732 95 13.0% 1 -[R346T] XBB.1.18.1 732 59 8.1% 2 -[R346T,K417N] XBB.1.18.1 732 27 3.7% 2 +[F456L]-[R346T] XBB.1.18.1 732 21 2.9% 3 +[F456L,H1083Y]-[R346T] BR.2 728 457 62.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BR.2 728 150 20.6% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I,S730F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2 728 15 2.1% 1 +[K147E,W152R,F157L,I210V,V213G,T240I,G257S,L452R,F486I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2 728 8 1.1% 2 +[A27-,K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486I]-[L24-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BR.2 728 7 1.0% 2 +[K147E,W152R,F157L,I210V,V213G,G257S,A348S,L452R,F486I,S730F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.333 727 650 89.4% 0 +[L54F,D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.333 727 15 2.1% 1 +[L54F,D138Y,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.333 727 9 1.2% 1 +[L54F,D138Y,T547I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.333 727 9 1.2% 1 +[S12F,L54F,D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.333 727 5 0.7% 1 +[L54F,D138Y,T572I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.301 725 401 55.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.301 725 139 19.2% 1 +[V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.301 725 95 13.1% 2 +[L5F,V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.301 725 18 2.5% 2 +[A222V,V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.301 725 13 1.8% 2 +[I68T,V687L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FY.5 722 243 33.7% 0 +[Y200C,T478R]-[T478K] (consensus) FY.5 722 168 23.3% 1 +[Y200C,T478R,T572I]-[T478K] FY.5 722 49 6.8% 4 +[M153I,F186S,Y200C,S247N,T478R,T572I]-[T478K] FY.5 722 23 3.2% 1 +[L176F,Y200C,T478R]-[T478K] FY.5 722 19 2.6% 1 +[Y200C,A222V,T478R]-[T478K] BA.2.3.18 720 327 45.4% 0 +[V213G,G339D,Q493R,I692F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.18 720 325 45.1% 1 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.18 720 4 0.6% 2 +[V213G,G339D,Q493R,A706V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.18 720 4 0.6% 1 +[V213G,G339D,Q493R,I692F,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.18 720 4 0.6% 1 +[I197V,V213G,G339D,Q493R,I692F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.1 720 602 83.6% 0 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.6.1 720 8 1.1% 2 +[H69-,V70-,W152L,V213G,G257S,G339D,L452R,F486V,N658S,D1168Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.1 720 7 1.0% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V,N658S,D1163Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.6.1 720 6 0.8% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,E484V,F486V,N658S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,E484A,F486P,F490S] BA.4.6.1 720 5 0.7% 1 +[H69-,V70-,W152L,V213G,G339D,L452R,F486V,N658S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.93 719 648 90.1% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.93 719 10 1.4% 1 +[A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.93 719 9 1.3% 1 +[D1146H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.93 719 5 0.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.93 719 5 0.7% 1 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.28 719 539 75.0% 0 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.28 719 52 7.2% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,A694V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.28 719 12 1.7% 1 +[H69-,V70-,V213G,P251L,S255F,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.28 719 11 1.5% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.28 719 10 1.4% 1 +[H69-,V70-,V213G,P251L,G339D,K444T,L452R,F486V,A684V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] B.1.111 717 214 29.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.111 717 175 24.4% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.111 717 67 9.3% 1 +[W152R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.111 717 28 3.9% 3 +[L249S,E484K,F1121L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.111 717 18 2.5% 1 +[D215G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.24 716 268 37.4% 0 +[H69-,V70-,V213G,T240I,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.24 716 224 31.3% 1 +[H69-,V70-,V213G,T240I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.24 716 54 7.5% 1 +[H69-,V70-,V213G,T240I,G339D,K444T,L452R,F486V,A701V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.24 716 52 7.3% 1 +[H69-,V70-,V213G,T240I,S255F,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.24 716 26 3.6% 2 +[F32V,H69-,V70-,V213G,T240I,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] AY.4.2.5 715 609 85.2% 0 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.2.5 715 48 6.7% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,L452R,P681R,M731I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.5 715 11 1.5% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,G446D,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.5 715 5 0.7% 1 +[T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,G446V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.2.5 715 4 0.6% 1 +[L5F,T19R,T95I,Y145H,E156G,F157-,R158-,A222V,Q414K,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.6 710 582 82.0% 0 +[L18F,Q23H,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.6 710 22 3.1% 1 +[L18F,Q23H,D215Y,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.6 710 22 3.1% 1 +[L18F,Q23H,A222V,A1020V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.6 710 17 2.4% 2 +[L18F,Q23H,A222V,G446V,D796H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.6 710 10 1.4% 1 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.170 706 487 69.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.170 706 86 12.2% 1 +[E583Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.170 706 40 5.7% 1 +[D80Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.170 706 6 0.8% 1 +[V1228L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.170 706 5 0.7% 1 +[H49Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.44 705 536 76.0% 0 +[V213G,G339D,S371Y,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.44 705 57 8.1% 1 +[L176F,V213G,G339D,S371Y,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] BA.2.44 705 22 3.1% 1 +[V213G,G339D,S371Y,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.44 705 6 0.9% 1 +[V213G,G339D,S371Y,K444R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S] BA.2.44 705 6 0.9% 1 +[V213G,G339D,S371Y,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,V445P,G446S,N460K,F486P,F490S,P681H] GK.2 702 470 67.0% 0 +[L455F,F456L,V511I] (consensus) GK.2 702 40 5.7% 2 +[L5F,F157L,L455F,F456L,V511I] GK.2 702 22 3.1% 1 +[N148T,L455F,F456L,V511I] GK.2 702 18 2.6% 1 +[K356T,L455F,F456L,V511I] GK.2 702 10 1.4% 1 +[L455F,F456L,V511I,K1205N] XBB.2.3.3 700 434 62.0% 0 +[K182N,D253G,P521S]-[G252V] (consensus) XBB.2.3.3 700 18 2.6% 1 +[H146K,K182N,D253G,P521S]-[H146Q,G252V] XBB.2.3.3 700 12 1.7% 1 +[K182N,D253G,P521S]-[G252V,K417N] XBB.2.3.3 700 10 1.4% 1 +[K182N,D253G,S494P,P521S]-[G252V] XBB.2.3.3 700 8 1.1% 1 +[K182N,D253G,F456L,P521S]-[G252V] BF.7.26 699 254 36.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.26 699 180 25.8% 1 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.26 699 36 5.2% 3 +[H69-,V70-,T76I,V213G,G339D,L452R,F486V,L822F,C1250F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.26 699 34 4.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,K1245R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.26 699 21 3.0% 1 +[H69-,V70-,H146-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.6 698 555 79.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.6 698 21 3.0% 1 +[K77M]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6 698 20 2.9% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.6 698 16 2.3% 3 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.6 698 6 0.9% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] BA.2.50 697 644 92.4% 0 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.50 697 13 1.9% 1 +[L212S,V213G,G339D,Q493R,E1151D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.50 697 7 1.0% 1 +[L212S,V213G,G339D,Q493R,I624T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.50 697 4 0.6% 1 +[S98F,L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.50 697 3 0.4% 1 +[L212S,V213G,G339D,Q493R,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EE.2 697 391 56.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EE.2 697 115 16.5% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.2 697 64 9.2% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.2 697 13 1.9% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.2 697 5 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A1078T]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EG.4 696 504 72.4% 0 (consensus) EG.4 696 19 2.7% 1 +[H146K]-[H146Q] EG.4 696 10 1.4% 1 -[K417N] EG.4 696 7 1.0% 2 +[S256L]-[Y144-] EG.4 696 7 1.0% 2 +[H146K,S256L]-[H146Q] B.1.22 696 534 76.7% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.22 696 40 5.7% 1 +[D215G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.22 696 34 4.9% 2 +[L452M,F486L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.22 696 14 2.0% 1 +[A1087S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.22 696 6 0.9% 1 +[F486L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.4.1 695 578 83.2% 0 +[F486S,S673G,T883I]-[F486P] (consensus) XBB.1.4.1 695 14 2.0% 1 +[F486S,S673G,T883I,L938F]-[F486P] XBB.1.4.1 695 6 0.9% 1 +[F486S,S673G,T883I]-[K417N,F486P] XBB.1.4.1 695 6 0.9% 1 +[H245Y,F486S,S673G,T883I]-[F486P] XBB.1.4.1 695 5 0.7% 1 +[N354K,F486S,S673G,T883I]-[F486P] B.1.1.189 694 171 24.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.189 694 155 22.3% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.189 694 47 6.8% 1 +[E654Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.189 694 28 4.0% 1 +[V483F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.189 694 14 2.0% 2 +[N282D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EE.1 694 546 78.7% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) EE.1 694 18 2.6% 1 +[H69-,V70-,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.1 694 15 2.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.1 694 10 1.4% 1 +[H69-,V70-,P209L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] EE.1 694 9 1.3% 2 +[H69-,V70-,S112L,K182E,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.72 692 502 72.5% 0 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.72 692 56 8.1% 1 +[L212S,V213G,D215E,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.72 692 23 3.3% 1 +[L212S,V213G,G339D,Q493R,T632N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.72 692 22 3.2% 1 +[L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.72 692 6 0.9% 1 +[L5F,L212S,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.1.1.6 692 616 89.0% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.6 692 22 3.2% 1 +[A67V,H69-,V70-,T76I,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.6 692 18 2.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,S254F,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.6 692 4 0.6% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F,I1169V]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.6 692 3 0.4% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] XBB.1.5.14 691 420 60.8% 0 (consensus) XBB.1.5.14 691 46 6.7% 1 +[A163S] XBB.1.5.14 691 12 1.7% 2 +[T19L,Q675H]-[T19I] XBB.1.5.14 691 11 1.6% 1 +[D1153Y] XBB.1.5.14 691 11 1.6% 1 +[H146K]-[H146Q] DU.1 687 473 68.9% 0 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,E1144Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) DU.1 687 67 9.8% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,E1144Q,P1162S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DU.1 687 24 3.5% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DU.1 687 12 1.7% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,L922F,E1144Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] DU.1 687 12 1.7% 1 +[H69-,V70-,V213G,D253G,G339D,K444T,L452R,F486V,T1117I,E1144Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BE.5 686 504 73.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.5 686 37 5.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,P1162L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.5 686 33 4.8% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.5 686 18 2.6% 2 +[H69-,V70-,G75V,W152L,V213G,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.5 686 9 1.3% 1 +[H69-,V70-,V213G,P251L,G339D,L452R,F486V,P1162L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.71 684 278 40.6% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.71 684 180 26.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.71 684 28 4.1% 1 +[T19R,T20I,E156G,F157-,R158-,A222V,L452R,P681R,D950N,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.71 684 11 1.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.71 684 10 1.5% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,A1078S,S1252F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] GY.5 683 490 71.7% 0 +[E180V,T478R]-[T478K] (consensus) GY.5 683 14 2.0% 1 +[H146K,E180V,T478R]-[H146Q,T478K] GY.5 683 14 2.0% 1 +[E180V,T478R]-[K417N,T478K] GY.5 683 11 1.6% 1 +[E180V,Q218P,T478R]-[T478K] GY.5 683 10 1.5% 1 +[E180V,T478R,T573I]-[T478K] XBB.1.5.5 683 242 35.4% 0 +[K1181I] (consensus) XBB.1.5.5 683 131 19.2% 1 +[G181V,K1181I] XBB.1.5.5 683 111 16.3% 1 +[T523A,K1181I] XBB.1.5.5 683 29 4.2% 2 +[E471Q,T523A,K1181I] XBB.1.5.5 683 10 1.5% 1 +[K1181I]-[K417N] Q.7 683 415 60.8% 0 +[H69-,V70-,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) Q.7 683 134 19.6% 1 +[H69-,V70-,M177T,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.7 683 23 3.4% 1 +[H69-,V70-,A570D,Q677H,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.7 683 11 1.6% 2 +[S12F,H69-,V70-,A570D,T678I,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] Q.7 683 8 1.2% 1 +[H69-,V70-,W258S,A570D,T716I,S982A,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.177.18 681 593 87.1% 0 +[A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.18 681 14 2.1% 1 +[T76I,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.18 681 12 1.8% 1 +[A222V,D427G,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.18 681 10 1.5% 1 +[A222V,E484Q,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.18 681 7 1.0% 1 +[A222V,E583D,R765L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.620 678 475 70.1% 0 +[P26S,H69-,V70-,V126A,L242-,A243-,L244-,H245Y,E484K,T1027I,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] (consensus) B.1.620 678 26 3.8% 4 +[P26S,H69-,V70-,V126A,E484K,T1027I,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.620 678 18 2.7% 1 +[P26S,H69-,V70-,V126A,N137S,L242-,A243-,L244-,H245Y,E484K,T1027I,D1118H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.620 678 12 1.8% 1 +[P26S,H69-,V70-,V126A,L242-,A243-,L244-,H245Y,E484K,T1027I,D1118H,V1133F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.620 678 8 1.2% 1 +[P26S,H69-,V70-,V126A,L242-,A243-,L244-,H245Y,E484K,T1027I,D1118H,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] AY.4.11 678 492 72.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.11 678 30 4.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.11 678 29 4.3% 1 +[T19R,T95I,I100L,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.11 678 13 1.9% 1 +[T19R,T29I,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.11 678 10 1.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1191M]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.14 678 545 80.4% 0 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.14 678 44 6.5% 1 +[L18F,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.14 678 15 2.2% 1 +[M153I,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.14 678 4 0.6% 1 +[N439K,G1219S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.14 678 4 0.6% 1 +[A67V,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.24 675 242 35.9% 0 +[Q613H,A688V] (consensus) FL.24 675 197 29.2% 1 +[T478R,Q613H,A688V]-[T478K] FL.24 675 11 1.6% 3 +[T478R,E554K,Q613H,A688V,T961M]-[T478K] FL.24 675 9 1.3% 2 +[T478R,K558N,Q613H,A688V]-[T478K] FL.24 675 9 1.3% 1 +[Q613H,A688V,T961M] XBB.1.16.17 673 265 39.4% 0 +[E180V,T478R,E554K]-[T478K] (consensus) XBB.1.16.17 673 165 24.5% 3 +[E180V,K182Q,F456L,T478R,E554K,A701V]-[T478K] XBB.1.16.17 673 60 8.9% 1 +[E180V,F456L,T478R,E554K]-[T478K] XBB.1.16.17 673 12 1.8% 1 +[H146K,E180V,T478R,E554K]-[H146Q,T478K] XBB.1.16.17 673 12 1.8% 3 +[E180V,F186S,T478R,E554Q,N556K]-[T478K] XBB.1.16.19 672 439 65.3% 0 +[E180V,T478R]-[T478K] (consensus) XBB.1.16.19 672 14 2.1% 1 +[T76A,E180V,T478R]-[T478K] XBB.1.16.19 672 13 1.9% 1 +[E180V,T323I,T478R]-[T478K] XBB.1.16.19 672 11 1.6% 1 +[H146K,E180V,T478R]-[H146Q,T478K] XBB.1.16.19 672 11 1.6% 2 +[E180V,T478R,S810L,E1150D]-[T478K] BN.1.1 672 490 72.9% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.1 672 9 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.1 672 9 1.3% 1 +[I68V,K147E,W152R,F157L,I210V,V213G,G257S,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.1 672 8 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,G261A,K356T,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.1 672 6 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,S494P,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.1.279 671 591 88.1% 0 +[R21I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.279 671 35 5.2% 1 +[R21I,L841R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.279 671 11 1.6% 1 +[R21I,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.279 671 4 0.6% 1 +[R21I,N211S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.279 671 3 0.4% 1 +[R21I,S255P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.9 668 595 89.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.9 668 22 3.3% 1 +[H69-,V70-,N185S,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.9 668 6 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.9 668 3 0.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G1124V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.9 668 3 0.4% 1 +[T22I,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.1.377 668 539 80.7% 0 +[I233V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.377 668 86 12.9% 1 +[I233V,T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.377 668 13 1.9% 1 +[I233V,G257S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.377 668 4 0.6% 1 +[I233V,V267L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.377 668 3 0.4% 1 +[I233V,T676P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.65 667 381 57.1% 0 (consensus) XBB.1.5.65 667 30 4.5% 2 -[R408S,S477N] XBB.1.5.65 667 26 3.9% 1 +[E619Q] XBB.1.5.65 667 16 2.4% 1 +[R78M] XBB.1.5.65 667 14 2.1% 3 -[R408S,S477N,Q954H] BQ.1.28 667 481 72.1% 0 +[H69-,V70-,V213G,Y248S,+248RWMD,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.28 667 86 12.9% 5 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.28 667 11 1.6% 1 +[T19L,H69-,V70-,V213G,Y248S,+248RWMD,G339D,K444T,L452R,F486V]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.28 667 5 0.7% 1 +[H69-,V70-,V213G,Y248S,+248RWMD,G339D,K444T,L452R,F486V,E554Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.28 667 4 0.6% 1 +[H69-,V70-,V213G,Y248S,+248RWMD,G339D,K444T,L452R,F486V,P621S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] C.16 666 240 36.0% 0 +[L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.16 666 121 18.2% 1 +[L452R,G769V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.16 666 58 8.7% 3 +[L452R,S640F,G769V,K854N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.16 666 25 3.8% 1 +[A411S,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.16 666 21 3.2% 1 +[L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,N764K,D796Y,Q954H,N969K] B.1.1.432 664 263 39.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.432 664 35 5.3% 1 +[A647V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.432 664 28 4.2% 1 +[T618S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.432 664 25 3.8% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.432 664 24 3.6% 1 +[A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.524 664 513 77.3% 0 +[A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.524 664 41 6.2% 1 +[R214L,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.524 664 10 1.5% 1 +[L452M,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.524 664 6 0.9% 3 +[R214L,E654A,A701V,T791I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.524 664 5 0.8% 2 +[R214L,A701V,L938F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.22 664 327 49.2% 0 +[G181V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.22 664 176 26.5% 1 +[L18F,G181V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.22 664 57 8.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.22 664 21 3.2% 2 +[L18F,G181V,A892S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.22 664 6 0.9% 2 +[V1133I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.1.1.9 661 553 83.7% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.1.9 661 58 8.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.9 661 11 1.7% 1 +[A67V,H69-,V70-,T95I,F140L,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.9 661 3 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.1.9 661 3 0.5% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,R346K,S371L,Q493R,G496S,T547K,Q677K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] C.17 659 260 39.5% 0 +[S12F,L452R,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) C.17 659 86 13.1% 2 +[Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.17 659 40 6.1% 1 +[L452R,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.17 659 16 2.4% 3 +[H49Y,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] C.17 659 14 2.1% 1 +[S12F,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.86 658 428 65.0% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.86 658 122 18.5% 1 +[T19R,E156G,F157-,R158-,P251L,L452R,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.86 658 23 3.5% 1 +[T19R,D80G,E156G,F157-,R158-,L452R,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.86 658 12 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.86 658 10 1.5% 1 +[T19R,E156G,F157-,R158-,L452R,Y660H,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.7.1 656 520 79.3% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] (consensus) P.1.7.1 656 15 2.3% 1 +[L5F,L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7.1 656 13 2.0% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E583D,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7.1 656 9 1.4% 2 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,E583D,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.7.1 656 8 1.2% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,K444N,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] AY.134 651 606 93.1% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.134 651 8 1.2% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,L841I,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.134 651 4 0.6% 1 +[L5F,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.134 651 3 0.5% 1 +[S13I,T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.134 651 3 0.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,M1229I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.8 651 561 86.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.8 651 36 5.5% 1 +[D1084E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.8 651 10 1.5% 1 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.8 651 10 1.5% 2 +[P26S,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.8 651 5 0.8% 3 +[P26S,E484D,S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BE.1.3 650 472 72.6% 0 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.1.3 650 62 9.5% 1 +[H69-,V70-,K147N,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.3 650 22 3.4% 1 +[L5F,H69-,V70-,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BE.1.3 650 11 1.7% 2 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BE.1.3 650 7 1.1% 1 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V,E1258Q]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BN.1.2.1 649 511 78.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T470N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.2.1 649 9 1.4% 1 +[L8F,K147E,W152R,F157L,I210V,V213G,G257S,K356T,T470N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.1 649 9 1.4% 1 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,K356T,T470N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.1 649 8 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T470N,T547K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.2.1 649 6 0.9% 2 +[K147E,W152R,F157L,I210V,V213G,K356T,T470N]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] CR.1.1 648 519 80.1% 0 +[V62I,H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CR.1.1 648 15 2.3% 1 +[V62I,H69-,V70-,V213G,G339D,K444R,L452R,F486V,S940A]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1.1 648 14 2.2% 1 +[V62I,H69-,V70-,V213G,G339D,T430I,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1.1 648 7 1.1% 2 +[V62I,H69-,V70-,F186Y,V213G,G339D,K444R,V445A,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] CR.1.1 648 6 0.9% 1 +[P9L,V62I,H69-,V70-,V213G,G339D,K444R,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] XBB.1.5.23 644 297 46.1% 0 (consensus) XBB.1.5.23 644 54 8.4% 1 +[H146K]-[H146Q] XBB.1.5.23 644 37 5.7% 1 +[H245Y] XBB.1.5.23 644 31 4.8% 1 -[R408S] XBB.1.5.23 644 21 3.3% 1 +[T19L]-[T19I] GR.1 643 445 69.2% 0 +[E281D,V445S]-[V445P] (consensus) GR.1 643 26 4.0% 1 +[H146K,E281D,V445S]-[H146Q,V445P] GR.1 643 19 3.0% 1 +[G75S,E281D,V445S]-[V445P] GR.1 643 13 2.0% 1 +[L249F,E281D,V445S]-[V445P] GR.1 643 11 1.7% 1 +[N148T,E281D,V445S]-[V445P] AY.91 643 198 30.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.91 643 158 24.6% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91 643 57 8.9% 2 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91 643 28 4.4% 1 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.91 643 20 3.1% 2 +[T19R,G75V,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.105 641 331 51.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.105 641 111 17.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.105 641 44 6.9% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.105 641 11 1.7% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,P812S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.105 641 9 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,R214L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.7.14.5 641 493 76.9% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.7.14.5 641 23 3.6% 1 +[H69-,V70-,V213G,R214L,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.5 641 6 0.9% 1 +[H69-,V70-,E96A,V213G,G339D,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.5 641 5 0.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,C1243F,G1267R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BF.7.14.5 641 4 0.6% 2 +[H69-,V70-,K182N,V213G,G339D,R346I,L452R,F486V,C1243F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.8 639 387 60.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.8 639 154 24.1% 3 +[A262S,Q314K,F486L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.8 639 15 2.3% 1 +[T716I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.8 639 13 2.0% 1 +[V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.8 639 9 1.4% 1 +[A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.2.58 639 504 78.9% 0 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.58 639 27 4.2% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.58 639 14 2.2% 1 +[T29I,H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.58 639 10 1.6% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.58 639 9 1.4% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.3.16 638 366 57.4% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.3.16 638 88 13.8% 1 +[V213G,G339D,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.16 638 88 13.8% 3 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S373P,S375F,T376A,V445P,G446S,N460K,F486P,F490S] BA.2.3.16 638 8 1.3% 2 +[V213G,G339D,Q493R,G1251A]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.3.16 638 6 0.9% 1 +[V213G,G339D,K444R,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.62 636 557 87.6% 0 +[L18F,T51I,A222V,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.62 636 16 2.5% 1 +[L18F,T51I,A222V,D936Y,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.62 636 10 1.6% 1 +[L5F,L18F,T51I,A222V,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.62 636 7 1.1% 1 +[L18F,T51I,T76I,A222V,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.62 636 6 0.9% 1 +[L18F,T51I,A222V,P337S,D936Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.3.7 636 388 61.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.7 636 41 6.4% 1 +[G75S,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.7 636 27 4.2% 3 +[G75S,H146L,K147E,W152R,F157L,I210V,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,G252V,L368I,V445P,F486P] BN.1.3.7 636 25 3.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V622F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.7 636 16 2.5% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,T478R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,T478K,F486P] FL.18 635 407 64.1% 0 (consensus) FL.18 635 22 3.5% 1 +[R78M] FL.18 635 20 3.1% 1 -[K417N] FL.18 635 14 2.2% 1 -[T478K] FL.18 635 9 1.4% 1 +[H146K]-[H146Q] JD.2 634 486 76.7% 0 (consensus) JD.2 634 18 2.8% 1 -[R408S] JD.2 634 12 1.9% 2 -[R346T,K417N] JD.2 634 7 1.1% 1 +[H146K]-[H146Q] JD.2 634 7 1.1% 1 -[R346T] AY.58 631 450 71.3% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.58 631 54 8.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.58 631 27 4.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.58 631 17 2.7% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P479S,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.58 631 8 1.3% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CN.1 631 355 56.3% 0 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) CN.1 631 164 26.0% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CN.1 631 12 1.9% 1 +[H69-,V70-,V213G,G252S,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CN.1 631 11 1.7% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,V1060I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] CN.1 631 5 0.8% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BN.1.9 630 485 77.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.9 630 16 2.5% 3 +[K147E,W152R,E156-,F157-,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,R346T,L368I,V445P,F486P] BN.1.9 630 12 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.9 630 5 0.8% 1 +[K147E,W152R,F157L,I210V,V213G,H245Y,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.9 630 5 0.8% 1 +[V70L,K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] FD.4 629 362 57.6% 0 (consensus) FD.4 629 44 7.0% 2 +[H146K,K182R]-[H146Q] FD.4 629 21 3.3% 1 +[P521S] FD.4 629 18 2.9% 2 +[T478R,T883I]-[T478K] FD.4 629 12 1.9% 3 +[H146K,K182R,T747I]-[H146Q] GK.2.1 628 416 66.2% 0 +[L455F,F456L,V511I] (consensus) GK.2.1 628 21 3.3% 2 +[Q14R,L455F,F456L,V511I,V1264L] GK.2.1 628 17 2.7% 1 +[K304N,L455F,F456L,V511I] GK.2.1 628 8 1.3% 1 +[L455F,F456L,V511I]-[K417N] GK.2.1 628 8 1.3% 1 +[L455F,F456L,V511I,Q1201K] B.1.1.294 628 286 45.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.294 628 65 10.4% 2 +[T95I,A688S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.294 628 40 6.4% 1 +[E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.294 628 13 2.1% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.294 628 10 1.6% 2 +[E96D,L948I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.42 627 454 72.4% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.42 627 34 5.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704L,T747I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.42 627 14 2.2% 1 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.42 627 10 1.6% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] BQ.1.1.42 627 7 1.1% 1 +[L5F,H69-,V70-,V213G,G339D,K444T,L452R,F486V,S704L]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.2.33 627 546 87.1% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.33 627 25 4.0% 1 +[H66N,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.33 627 11 1.8% 1 +[V213G,G339D,Q493R,I1114T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.33 627 7 1.1% 1 +[V213G,R214L,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.33 627 6 1.0% 1 +[V213G,G339D,Q493R,T791I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EG.1.3 626 421 67.3% 0 +[Q613H] (consensus) EG.1.3 626 14 2.2% 1 +[D253Y,Q613H] EG.1.3 626 8 1.3% 1 +[H146K,Q613H]-[H146Q] EG.1.3 626 6 1.0% 1 +[Q613H]-[R408S] EG.1.3 626 6 1.0% 1 +[Y451H,Q613H] AY.9.2.2 624 457 73.2% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,Q675K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.9.2.2 624 40 6.4% 1 +[T19R,V70L,E156G,F157-,R158-,A222V,L452R,Q675K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.2 624 16 2.6% 2 +[T19R,E156G,F157-,R158-,A222V,L452R,Q675K,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.2 624 16 2.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q675K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.9.2.2 624 14 2.2% 1 +[T19R,E156G,F157-,R158-,G181V,A222V,L452R,Q675K,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBC.1 623 435 69.8% 0 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] (consensus) XBC.1 623 24 3.9% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I,Q1208H]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1 623 23 3.7% 1 +[P25S,A67S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1 623 12 1.9% 2 +[P25S,A67S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] XBC.1 623 10 1.6% 1 +[P25S,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,L452M,N703I]-[L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,N460K,F490S] AY.28 621 458 73.8% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,A701S,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.28 621 7 1.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,E484Q,P681R,A701S,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.28 621 7 1.1% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,Q613H,P681R,A701S,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.28 621 5 0.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,T573I,P681R,A701S,D950N,A1078S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.28 621 4 0.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,A701S,D950N,A1078S,Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BF.18 620 505 81.5% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.18 620 21 3.4% 1 +[H69-,V70-,V213G,G339D,R346S,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.18 620 16 2.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,D1199H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.18 620 11 1.8% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.18 620 4 0.6% 1 +[H69-,V70-,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] B.1.576 619 522 84.3% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.576 619 15 2.4% 1 +[G75V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.576 619 6 1.0% 2 +[T572I,K1181R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.576 619 5 0.8% 1 +[H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.576 619 4 0.6% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.9 618 326 52.8% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.43.9 618 151 24.4% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.9 618 42 6.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,N960K]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.9 618 16 2.6% 1 +[T19R,M153I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.43.9 618 6 1.0% 1 +[T19R,E156G,F157-,R158-,S221L,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.10 617 468 75.9% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.10 617 43 7.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.10 617 17 2.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,H1101Y]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.10 617 11 1.8% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.10 617 9 1.5% 2 +[T19R,I105V,E156G,F157-,R158-,A222V,A243S,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.13 610 546 89.5% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) P.1.13 610 5 0.8% 1 +[L18F,T20N,P26S,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.13 610 5 0.8% 1 +[L18F,T20N,P25L,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.13 610 4 0.7% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F,G1223S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.13 610 3 0.5% 1 +[L18F,T20N,P26S,D138Y,R190S,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.280 610 497 81.5% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.280 610 9 1.5% 1 +[A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.280 610 8 1.3% 1 +[G1219C]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.280 610 7 1.1% 1 +[E406Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.280 610 6 1.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.8.2 609 448 73.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.8.2 609 90 14.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V,V1164I]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BQ.1.8.2 609 8 1.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.8.2 609 5 0.8% 2 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619D,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S,P681H] BQ.1.8.2 609 4 0.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,E619D,A688V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] XBB.1.17.1 608 271 44.6% 0 +[D215H] (consensus) XBB.1.17.1 608 25 4.1% 1 +[H146K,D215H]-[H146Q] XBB.1.17.1 608 21 3.5% 1 +[D215H,T284I] XBB.1.17.1 608 14 2.3% 10 +[N148T,M177K,D178-,L179-,K182-,Q183-,G184-,D215H,Q218R,S494P,P521S]-[Q183E] XBB.1.17.1 608 13 2.1% 1 +[D215H,P812S] AY.32 608 303 49.8% 0 +[T19R,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.32 608 40 6.6% 1 +[T19R,E156G,F157-,R158-,T250I,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.32 608 30 4.9% 2 +[T19R,Y28F,E156G,F157-,R158-,L216F,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.32 608 27 4.4% 2 +[T19R,E156G,F157-,R158-,L452R,T572I,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.32 608 24 3.9% 1 +[T19R,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.361 607 493 81.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.361 607 35 5.8% 1 +[D1163G]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.361 607 9 1.5% 1 +[P499S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.361 607 6 1.0% 1 +[A626S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.361 607 4 0.7% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CK.1.4 606 503 83.0% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) CK.1.4 606 14 2.3% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] CK.1.4 606 13 2.1% 1 +[H69-,V70-,V213G,T307I,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.4 606 6 1.0% 1 +[H69-,V70-,V213G,G339D,S359N,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] CK.1.4 606 5 0.8% 1 +[L5F,H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] BA.1.17.1 605 557 92.1% 0 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] (consensus) BA.1.17.1 605 6 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,A260T,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.1 605 6 1.0% 1 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,R765L,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.1 605 5 0.8% 3 +[A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BA.1.17.1 605 4 0.7% 1 +[L5F,A67V,H69-,V70-,T95I,V143-,Y145-,N211-,L212I,+214EPE,G339D,S371L,Q493R,G496S,T547K,N856K,L981F]-[T19I,L24-,P25-,P26-,A27S,V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,T376A,D405N,R408S,V445P,N460K,F486P,F490S] BQ.1.1.11 605 345 57.0% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.11 605 63 10.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P,Q1208H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.11 605 56 9.3% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.11 605 12 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.11 605 10 1.7% 2 +[H69-,V70-,V213G,H245Y,G339D,K444T,L452R,F486V,S494P]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] FL.12 604 354 58.6% 0 (consensus) FL.12 604 119 19.7% 1 +[D1084E] FL.12 604 11 1.8% 1 +[H146K]-[H146Q] FL.12 604 7 1.2% 1 +[G1085R] FL.12 604 7 1.2% 1 -[K417N] B.1.1.192 602 295 49.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.192 602 192 31.9% 1 +[D138H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.192 602 36 6.0% 1 +[F157S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.192 602 10 1.7% 2 +[F157S,T678A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.192 602 5 0.8% 2 +[D138H,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.4.5 601 371 61.7% 0 (consensus) FL.4.5 601 24 4.0% 1 +[G181E] FL.4.5 601 15 2.5% 1 +[V952I] FL.4.5 601 14 2.3% 2 +[R190S,P521S] FL.4.5 601 14 2.3% 1 +[N856S] B.1.428 601 408 67.9% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.428 601 45 7.5% 1 +[D138Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428 601 35 5.8% 1 +[N481K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428 601 10 1.7% 2 +[D138Y,P812S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.428 601 9 1.5% 1 +[K97E]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.54 599 445 74.3% 0 +[V213G,Y248S,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.54 599 39 6.5% 1 +[V213G,Y248S,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.2.54 599 29 4.8% 1 +[V213G,Y248S,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.54 599 15 2.5% 1 +[V213G,Y248S,G339D,Q493R,E1202Q,V1228L]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.54 599 11 1.8% 1 +[V213G,Y248S,G339D,Q493R,E1202Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] XBB.1.5.62 598 329 55.0% 0 (consensus) XBB.1.5.62 598 20 3.3% 1 +[H1101Y] XBB.1.5.62 598 16 2.7% 1 +[H146K]-[H146Q] XBB.1.5.62 598 14 2.3% 1 +[E583Q] XBB.1.5.62 598 12 2.0% 1 +[W152R] AY.4.12 598 518 86.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.4.12 598 27 4.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,S680F,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.12 598 16 2.7% 1 +[T19R,T95I,E156G,F157-,R158-,V193L,L452R,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.12 598 5 0.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T676I,P681R,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.4.12 598 3 0.5% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,I896T,D950N,P1162S]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.20 598 556 93.0% 0 +[A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.20 598 10 1.7% 1 +[L141V,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.20 598 6 1.0% 1 +[M177I,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.20 598 5 0.8% 1 +[L5F,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.20 598 3 0.5% 1 +[A222V,E583D,P1263S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BM.1.1 597 357 59.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.1.1 597 26 4.4% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1 597 24 4.0% 1 +[L5F,K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1 597 17 2.8% 1 +[K147E,W152R,F157L,N185S,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.1.1 597 12 2.0% 4 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BE.4.1 595 364 61.2% 0 +[H69-,V70-,P209L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BE.4.1 595 55 9.2% 1 +[H69-,V70-,G181V,P209L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.1 595 14 2.4% 1 +[H69-,V70-,F135I,P209L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.1 595 14 2.4% 1 +[H69-,V70-,Q183L,P209L,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BE.4.1 595 13 2.2% 1 +[H69-,V70-,P209L,V213G,G339D,V445A,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] B.1.177.33 595 380 63.9% 0 +[A222V,G639S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.33 595 69 11.6% 1 +[A222V,G639S,A672V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.33 595 38 6.4% 1 +[A222V,G639S,V1264L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.33 595 10 1.7% 1 +[A222V,G639S,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.33 595 6 1.0% 1 +[L5F,A222V,G639S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.87 594 523 88.0% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.87 594 12 2.0% 1 +[L5F,T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.87 594 8 1.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,K1073N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.87 594 5 0.8% 3 +[T19R,E156G,F157-,R158-,L452R,N679T,S680R,P681-,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.87 594 4 0.7% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D936Y,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.30 594 435 73.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.30 594 46 7.7% 1 +[K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.30 594 15 2.5% 2 +[A879V,K1191N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.30 594 13 2.2% 1 +[S494P]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.30 594 10 1.7% 1 +[K558N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BQ.1.1.17 594 446 75.1% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.17 594 26 4.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.17 594 17 2.9% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S940F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.17 594 6 1.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,A688D]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.17 594 5 0.8% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BA.2.39 592 540 91.2% 0 +[V213G,G339D,Q493R,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.39 592 8 1.4% 1 +[V213G,G339D,Q493R,L858I,G1219V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.39 592 6 1.0% 1 +[H49Y,V213G,G339D,Q493R,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.39 592 5 0.8% 1 +[V213G,G339D,Q493R,L858I,D950N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.39 592 4 0.7% 1 +[V213G,G339D,Q493R,L858I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] B.1.177.83 592 259 43.8% 0 +[A222V,A262S,P272L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.83 592 105 17.7% 1 +[A222V,A262S,P272L,L452R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.83 592 72 12.2% 2 +[A222V,A262S,P272L,L452R,V1268I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.83 592 29 4.9% 1 +[A222V,A262S,P272L,L1224F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.83 592 7 1.2% 2 +[A222V,A262S,P272L,L452R,T859I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.7 591 364 61.6% 0 +[K147E,W152R,F157L,M177T,+209V,N211G,L212-,V213-,G257S,K356T,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.7 591 81 13.7% 1 +[V62I,K147E,W152R,F157L,M177T,+209V,N211G,L212-,V213-,G257S,K356T,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.7 591 45 7.6% 1 +[K147E,W152R,F157L,M177T,+209V,N211G,L212-,V213-,G257S,K356T,N751D,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.7 591 14 2.4% 1 +[K147E,W152R,F157L,M177T,G181V,+209V,N211G,L212-,V213-,G257S,K356T,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.7 591 10 1.7% 1 +[K147E,W152R,F157L,M177T,+209V,N211G,L212-,V213-,G257S,K356T,H1101Y,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BQ.1.1.29 589 333 56.5% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.1.29 589 114 19.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.29 589 12 2.0% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,K417N,V445P,G446S,F486P,F490S] BQ.1.1.29 589 10 1.7% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,S494P,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.1.29 589 7 1.2% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V,Q613H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,R408S,V445P,G446S,F486P,F490S] CH.1.1.26 589 456 77.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.26 589 13 2.2% 5 +[K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.26 589 8 1.4% 4 +[I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.26 589 7 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.26 589 5 0.8% 1 +[K147E,W152R,F157L,M177I,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.1.141 585 351 60.0% 0 +[M153T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.141 585 40 6.8% 2 +[M153T,T385I,P681R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.141 585 36 6.2% 1 +[M153T,N540S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.141 585 29 5.0% 1 +[M153T,T385I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.141 585 12 2.1% 1 +[M153T,Y351F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.88 582 184 31.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.88 582 86 14.8% 1 +[T19R,E156G,F157-,R158-,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.88 582 75 12.9% 2 +[T19R,T124S,E156G,F157-,R158-,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.88 582 25 4.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.88 582 22 3.8% 2 +[T19R,E156G,F157-,R158-,Q414R,L452R,S680F,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FL.8 580 334 57.6% 0 (consensus) FL.8 580 66 11.4% 1 +[S256L] FL.8 580 21 3.6% 1 +[D1084Y] FL.8 580 16 2.8% 2 +[S256L,E465D] FL.8 580 10 1.7% 1 -[K417N] XCH.1 579 389 67.2% 0 +[L455F,F456L,T573I,S704L] (consensus) XCH.1 579 36 6.2% 1 +[L455F,F456L,T573I,Q677H,S704L] XCH.1 579 13 2.2% 1 +[L455F,F456L,T478R,T573I,S704L]-[T478K] XCH.1 579 12 2.1% 1 +[H146K,L455F,F456L,T573I,S704L]-[H146Q] XCH.1 579 9 1.6% 2 +[A262D,L455F,F456L,A475V,T573I,S704L] BQ.1.22 579 264 45.6% 0 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] (consensus) BQ.1.22 579 72 12.4% 1 +[H69-,V70-,V213G,G339D,K444T,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.22 579 58 10.0% 1 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.22 579 31 5.4% 2 +[H69-,V70-,F157L,V213G,G339D,K444T,L452R,F486V,V608I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BQ.1.22 579 8 1.4% 3 +[H69-,V70-,F157L,V213G,T307I,G339D,K444T,L452R,F486V,Q1201K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,F486P,F490S] BA.4.1.4 579 449 77.5% 0 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.4.1.4 579 27 4.7% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.4.1.4 579 19 3.3% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BA.4.1.4 579 15 2.6% 1 +[V3G,H69-,V70-,V213G,G339D,L452R,F486V,I934V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.4.1.4 579 11 1.9% 1 +[V3G,H69-,V70-,A93S,V213G,G339D,L452R,F486V,C1235F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.24 579 483 83.4% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.24 579 18 3.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.24 579 14 2.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.24 579 8 1.4% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.24 579 5 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,A1020S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] FL.1.5.2 578 405 70.1% 0 +[F456L,N481K,F490P,P681R,A701V]-[F490S,P681H] (consensus) FL.1.5.2 578 51 8.8% 1 +[F456L,N481K,P681R,A701V]-[P681H] FL.1.5.2 578 24 4.2% 1 +[F456L,N481K,F490P,P681R,A701V,V1228L]-[F490S,P681H] FL.1.5.2 578 14 2.4% 3 +[V83T,K356T,F456L,N481K,F490P,T572I,P681R,A701V]-[V83A,F490S,P681H] FL.1.5.2 578 5 0.9% 1 +[D138E,F456L,N481K,F490P,P681R,A701V]-[F490S,P681H] B.1.177.19 578 550 95.2% 0 +[A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.19 578 4 0.7% 1 +[L5F,A222V,E583D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.19 578 3 0.5% 1 +[A222V,E583D,T1027I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.19 578 3 0.5% 1 +[A222V,E583D,P809S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.19 578 2 0.3% 1 +[A222V,E583D,A684V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.5.1.9 577 475 82.3% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.1.9 577 36 6.2% 2 +[F32L,H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.1.9 577 10 1.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.9 577 8 1.4% 2 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.1.9 577 4 0.7% 1 +[H69-,V70-,M153I,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.2 577 457 79.2% 0 +[V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.2 577 33 5.7% 2 +[H69-,V70-,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.2 577 29 5.0% 1 +[L179P,V213G,G339D,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.2 577 7 1.2% 1 +[V213G,G339D,Q493R,I1210V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.2 577 6 1.0% 1 +[V213G,G339D,Q493R,E1144Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] A.27 576 317 55.0% 0 +[L18F,L452R,A653V,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] (consensus) A.27 576 79 13.7% 1 +[L18F,L452R,A653V,Q677H,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] A.27 576 26 4.5% 1 +[L18F,H49Y,L452R,A653V,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] A.27 576 16 2.8% 2 +[L18F,L452R,A653V,Q677H,K1191N,G1219V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] A.27 576 10 1.7% 1 +[L18F,L452R,A653V,G1219V]-[T19I,L24-,P25-,P26-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,D614G,N679K,P681H,N764K,Q954H,N969K] B.1.1.433 576 494 85.8% 0 +[S477R,S673T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.433 576 22 3.8% 1 +[S477R,S673T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.433 576 17 3.0% 1 +[S477R,S673T,V1104L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.433 576 9 1.6% 1 +[S477R,S673T,G946V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] B.1.1.433 576 4 0.7% 1 +[V143F,S477R,S673T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,P681H,N764K,D796Y,Q954H,N969K] AY.66 575 417 72.5% 0 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.66 575 52 9.0% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.66 575 10 1.7% 1 +[T19R,E156G,F157-,R158-,A222V,V367I,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.66 575 9 1.6% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,T1231A]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.66 575 7 1.2% 1 +[T19R,E156G,F157-,R158-,A222V,L452R,P681R,D950N,S1242N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] FY.3.2 574 424 73.9% 0 +[Y200C] (consensus) FY.3.2 574 14 2.4% 1 +[H146K,Y200C]-[H146Q] FY.3.2 574 9 1.6% 2 +[H69-,V70-,Y200C] FY.3.2 574 6 1.0% 1 +[L5F,Y200C] FY.3.2 574 4 0.7% 1 +[Y200C,A522V] B.1.324 574 265 46.2% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.324 574 161 28.0% 1 +[V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.324 574 16 2.8% 2 +[I1114L,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.324 574 13 2.3% 1 +[T307I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.324 574 9 1.6% 1 +[M153V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.108 573 147 25.7% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.108 573 143 25.0% 2 +[T19R,T95I,E156G,F157-,R158-,L452R,E484Q,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.108 573 69 12.0% 1 +[T19R,T95I,E156G,F157-,R158-,Y248H,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.108 573 22 3.8% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.108 573 16 2.8% 3 +[T19R,T95I,E156G,F157-,R158-,A243V,L452R,E484Q,P681R,D950N,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362 573 353 61.6% 0 +[L452R,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.362 573 85 14.8% 2 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362 573 38 6.6% 3 +[V1228A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362 573 8 1.4% 3 +[+256S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.362 573 6 1.0% 4 +[L5F,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.1 571 447 78.3% 0 +[F486S]-[F486P] (consensus) XBB.1.1 571 7 1.2% 2 +[V1228L]-[F486P] XBB.1.1 571 7 1.2% 1 +[F486S,P521T]-[F486P] XBB.1.1 571 6 1.1% 1 +[L5F,F486S]-[F486P] XBB.1.1 571 5 0.9% 1 +[F486S,E1111Q]-[F486P] B.1.160.17 571 465 81.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.160.17 571 58 10.2% 1 +[A942T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.17 571 18 3.2% 2 +[S373L,A942T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.17 571 7 1.2% 1 +[G75R]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.160.17 571 2 0.4% 1 +[R214S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] HK.1 570 153 26.8% 0 +[Q52H,G257V,F456L] (consensus) HK.1 570 84 14.7% 2 +[Q52H,G257V,T307I,L455F,F456L] HK.1 570 55 9.6% 2 +[Q52H,L455F,F456L] HK.1 570 40 7.0% 1 +[Q52H,G257V,F456L,P1263L] HK.1 570 34 6.0% 1 +[Q52H,G257V,L455F,F456L] BA.5.2.4 570 491 86.1% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.4 570 9 1.6% 1 +[H69-,V70-,D138N,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.4 570 5 0.9% 1 +[L5F,H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.4 570 5 0.9% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.2.4 570 4 0.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,T547I,V622I]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.4 568 396 69.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.3.4 568 44 7.7% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,G769V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.4 568 23 4.0% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.5.3.4 568 14 2.5% 1 +[H69-,V70-,Q173H,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.3.4 568 9 1.6% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S,P681H] FL.3.1 567 437 77.1% 0 (consensus) FL.3.1 567 8 1.4% 1 +[S494P] FL.3.1 567 8 1.4% 1 +[H245Y] FL.3.1 567 7 1.2% 1 +[V1122L] FL.3.1 567 5 0.9% 1 +[T883I] XBB.9 566 442 78.1% 0 +[F486S]-[G252V,F486P] (consensus) XBB.9 566 23 4.1% 1 +[F486S]-[G252V,K417N,F486P] XBB.9 566 17 3.0% 1 +[H146K,F486S]-[H146Q,G252V,F486P] XBB.9 566 8 1.4% 1 +[F486S]-[G252V,L368I,F486P] XBB.9 566 8 1.4% 1 +[S254F,F486S]-[G252V,F486P] BF.41 565 408 72.2% 0 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BF.41 565 27 4.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BF.41 565 17 3.0% 1 +[H69-,V70-,L176F,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BF.41 565 16 2.8% 1 +[H69-,V70-,V213G,G339D,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,N460K,F486P,F490S] BF.41 565 12 2.1% 1 +[H69-,V70-,V213G,G339D,L452R,F486V,H1101Y]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] EG.13 561 337 60.1% 0 (consensus) EG.13 561 28 5.0% 1 +[A623V] EG.13 561 13 2.3% 2 +[L176F,L1244F] EG.13 561 12 2.1% 1 +[L858I] EG.13 561 12 2.1% 1 +[H146K]-[H146Q] B.1.177.9 561 475 84.7% 0 +[D80Y,N164T,A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.9 561 25 4.5% 1 +[D80Y,T95I,N164T,A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.9 561 14 2.5% 1 +[D80Y,N164T,A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.9 561 7 1.2% 1 +[D80Y,N164T,A222V,A262S,I1216V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.9 561 5 0.9% 1 +[D80Y,S98F,N164T,A222V,A262S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.2 561 525 93.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.103.2 561 11 2.0% 1 +[T19R,E156G,F157-,R158-,E224A,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.2 561 5 0.9% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,T1116I]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.103.2 561 3 0.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,Q954H,N969K] AY.103.2 561 3 0.5% 1 +[T19R,D138Y,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] EG.10.1 560 379 67.7% 0 +[A344T,R403K,S494P,A701V] (consensus) EG.10.1 560 21 3.8% 1 +[H146K,A344T,R403K,S494P,A701V]-[H146Q] EG.10.1 560 7 1.2% 1 +[A344T,S494P,A701V] EG.10.1 560 6 1.1% 1 +[A344T,R403K,S494P,A701V,D1260N] EG.10.1 560 6 1.1% 1 +[A344T,R403K,S494P,A701V,T961M] W.4 560 475 84.8% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) W.4 560 26 4.6% 1 +[A222V,A653V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.4 560 8 1.4% 1 +[P9S,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.4 560 6 1.1% 1 +[T22I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] W.4 560 6 1.1% 1 +[A222V,L1063F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BM.4.1.1 560 375 67.0% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) BM.4.1.1 560 30 5.4% 2 +[L5F,K147E,W152R,F157L,G181A,I210V,V213G,G257S,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.4.1.1 560 7 1.2% 2 +[K147E,W152R,F157L,I210V,V213G,D215G,G257S,F486S,S494P]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.4.1.1 560 7 1.2% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S,S1252F]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BM.4.1.1 560 6 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,F486S]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] B.1.177.32 559 458 81.9% 0 +[A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.32 559 11 2.0% 1 +[A222V,A1020S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.32 559 8 1.4% 1 +[W152L,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.32 559 5 0.9% 1 +[A222V,A846V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.32 559 4 0.7% 1 +[A222V,V367F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.9.1 558 476 85.3% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.9.1 558 36 6.5% 4 +[V213G,G339D,L452M,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.1 558 7 1.3% 1 +[V213G,H245N,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.1 558 4 0.7% 1 +[V213G,G339D,L452M,Q493R]-[T19I,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.9.1 558 3 0.5% 1 +[V213G,G339D,K417I,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,N460K,F486P,F490S] B.1.177.58 558 478 85.7% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.58 558 18 3.2% 1 +[L18F,G181V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.58 558 14 2.5% 1 +[L18F,A222V,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.58 558 12 2.2% 1 +[L18F,A222V,A771S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.58 558 7 1.3% 1 +[L18F,A222V,T604I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.47 557 344 61.8% 0 (consensus) XBB.1.5.47 557 11 2.0% 1 +[H146K]-[H146Q] XBB.1.5.47 557 9 1.6% 1 +[H1058Y] XBB.1.5.47 557 9 1.6% 1 +[T259I] XBB.1.5.47 557 8 1.4% 1 -[K417N] B.1.177.5 556 461 82.9% 0 +[L18F,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.5 556 21 3.8% 1 +[L18F,T22I,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.5 556 20 3.6% 1 +[L18F,A222V,S689I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.5 556 6 1.1% 1 +[L18F,G184V,A222V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.5 556 6 1.1% 2 +[L18F,A222V,E484Q,S689I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BA.2.74 554 422 76.2% 0 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.2.74 554 16 2.9% 1 +[V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,N440K,V445P,G446S,N460K,F486P,F490S] BA.2.74 554 16 2.9% 4 +[V213G,G339D,L452M,Q493R]-[L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.74 554 8 1.4% 1 +[L5F,V213G,G339D,L452M,Q493R]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] BA.2.74 554 8 1.4% 1 +[V213G,G339D,L452M,Q493R]-[V83A,H146Q,Q183E,V213E,G252V,G339H,L368I,V445P,G446S,N460K,F486P,F490S] AY.104 553 357 64.6% 0 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.104 553 11 2.0% 1 +[T19R,R21I,T95I,E156G,F157-,R158-,L452R,T572I,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.104 553 8 1.4% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,A845S,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.104 553 7 1.3% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,F888L,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.104 553 6 1.1% 1 +[T19R,T95I,E156G,F157-,R158-,L452R,T572I,P681R,D950N,Q1180K]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.391 552 477 86.4% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.391 552 31 5.6% 1 +[V622F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.391 552 4 0.7% 1 +[E471Q]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.391 552 3 0.5% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.391 552 2 0.4% 1 +[T299A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.83 547 388 70.9% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.83 547 101 18.5% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.83 547 7 1.3% 1 +[T19R,R21I,E156G,F157-,R158-,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.83 547 4 0.7% 2 +[T19R,E156G,F157-,R158-,G181V,L452R,P681R,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.83 547 3 0.5% 2 +[V16F,T19R,E156G,F157-,R158-,L452R,P681R,L938F,D950N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] CH.1.1.10 547 347 63.4% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CH.1.1.10 547 104 19.0% 1 +[K147E,W152R,F157L,N185D,I210V,V213G,G257S,K444T,L452R,F486S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.10 547 24 4.4% 2 +[W64R,K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CH.1.1.10 547 10 1.8% 3 +[K147E,W152R,F157L,I210V,V213G,G257S,K444T,L452R,F486S,T678-,+679K]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S,N679K] CH.1.1.10 547 4 0.7% 4 +[W64R,K147E,W152R,F157L,I210V,V213G,+255L,G257-,K444T,L452R,F486S,P1162S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BA.5.2.53 546 386 70.7% 0 +[H69-,V70-,V213G,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] (consensus) BA.5.2.53 546 93 17.0% 1 +[H69-,V70-,V213G,G339D,N450D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.53 546 13 2.4% 1 +[H69-,V70-,V213G,L242F,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.53 546 6 1.1% 3 +[H69-,V70-,V213G,G339D,V445F,N450D,L452R,F486V,T547K,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] BA.5.2.53 546 5 0.9% 1 +[H69-,V70-,V213G,S247N,G339D,L452R,F486V,A653V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,N460K,F486P,F490S] AY.52 545 363 66.6% 0 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1141W]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) AY.52 545 78 14.3% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1141W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.52 545 10 1.8% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,A684S,D950N,L1141W]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.52 545 7 1.3% 2 +[T19R,E156G,F157-,R158-,L452R,P681R,L1141W]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] AY.52 545 6 1.1% 1 +[T19R,E156G,F157-,R158-,L452R,P681R,D950N,L1141W,K1181N]-[T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] P.1.6 544 446 82.0% 0 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] (consensus) P.1.6 544 25 4.6% 1 +[L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.6 544 15 2.8% 1 +[L5F,L18F,T20N,P26S,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.6 544 13 2.4% 1 +[L18F,T20N,P26S,A27T,D138Y,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] P.1.6 544 9 1.7% 4 +[L18F,T20N,P26S,D138Y,L141F,G142-,V143-,R190S,K417T,E484K,T1027I,V1176F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,N679K,N764K,D796Y,Q954H,N969K] B.1.1.269 544 473 86.9% 0 +[D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.1.269 544 15 2.8% 1 +[T95I,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.269 544 9 1.7% 1 +[L5F,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.269 544 4 0.7% 1 +[D936Y,D1084Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.1.269 544 3 0.6% 1 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] BN.1.3.2 543 401 73.8% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.2 543 18 3.3% 4 +[I210V,V213G,G257S,K356T,V445A]-[V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.2 543 15 2.8% 1 +[K147E,W152R,F157L,I210V,V213G,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.2 543 11 2.0% 1 +[K147E,W152R,F157L,I210A,V213G,G257S,K356T,V445A]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.2 543 9 1.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,V445A,N703S]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.351.3 541 210 38.8% 0 +[L18F,A67V,D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.3 541 208 38.4% 1 +[L18F,D80A,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.351.3 541 9 1.7% 4 +[L18F,D80A,D215G,L242-,A243-,L244-,R246-,S247-,Y248-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.3 541 7 1.3% 4 +[L18F,D80A,D215G,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.351.3 541 6 1.1% 2 +[L18F,D80A,D138N,D215G,L242-,A243-,L244-,E484K,A701V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.16 540 516 95.6% 0 +[N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.258.16 540 4 0.7% 1 +[S112P,N439K]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.16 540 3 0.6% 1 +[N439K,I472V]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.16 540 2 0.4% 1 +[N439K,Q677H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.258.16 540 1 0.2% 1 +[N439K,T747I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466 538 210 39.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.466 538 71 13.2% 1 +[S12F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466 538 11 2.0% 2 +[S12F,Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466 538 9 1.7% 1 +[Q675H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.466 538 8 1.5% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.1 538 509 94.6% 0 +[M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) L.1 538 7 1.3% 1 +[A262S,M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.1 538 5 0.9% 1 +[I1132V,M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.1 538 2 0.4% 1 +[P681L,M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] L.1 538 1 0.2% 1 +[P579S,M1237T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3.1 538 498 92.6% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.3.1 538 16 3.0% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3.1 538 10 1.9% 1 +[V615I]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3.1 538 2 0.4% 1 +[E96D]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.3.1 538 1 0.2% 1 +[Q1208H]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] DJ.1.1 537 296 55.1% 0 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] (consensus) DJ.1.1 537 72 13.4% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,V445P,G446S,F486P,F490S] DJ.1.1 537 55 10.2% 2 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DJ.1.1 537 48 8.9% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,R408S,V445P,G446S,F486P,F490S] DJ.1.1 537 4 0.7% 1 +[H69-,V70-,V213G,G339D,K444N,L452R,F486V]-[V83A,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,K417N,V445P,G446S,F486P,F490S] B.1.36.38 534 378 70.8% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.36.38 534 77 14.4% 1 +[L5F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.38 534 16 3.0% 1 +[L18F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.38 534 11 2.1% 1 +[P384L]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.36.38 534 5 0.9% 1 +[V1065A]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.28 532 212 39.8% 0 +[T478R]-[T478K] (consensus) XBB.1.5.28 532 47 8.8% 1 +[T478R,C1247F]-[T478K] XBB.1.5.28 532 28 5.3% 1 +[Q183D,T478R]-[Q183E,T478K] XBB.1.5.28 532 21 3.9% 2 +[F157S,G252I,T478R]-[G252V,T478K] XBB.1.5.28 532 17 3.2% 2 +[G181A,T478R,E619Q]-[T478K] CA.7 531 402 75.7% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] (consensus) CA.7 531 25 4.7% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,Q613H,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.7 531 10 1.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,T747I,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] CA.7 531 7 1.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P,F490S] CA.7 531 5 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,L452R,F486S,P621S,D1199N]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P,F490S] BN.1.3.12 530 425 80.2% 0 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] (consensus) BN.1.3.12 530 23 4.3% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,R408S,V445P,F486P] BN.1.3.12 530 6 1.1% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,Q675H]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.12 530 6 1.1% 1 +[K147E,W152R,F157L,N164S,I210V,V213G,G257S,K356T]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] BN.1.3.12 530 5 0.9% 1 +[K147E,W152R,F157L,I210V,V213G,G257S,K356T,E471Q]-[V83A,Y144-,H146Q,Q183E,V213E,G252V,L368I,V445P,F486P] B.1.127 529 492 93.0% 0 -[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.127 529 17 3.2% 1 +[H146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.127 529 3 0.6% 2 +[H66Q,H146Y]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.127 529 2 0.4% 1 +[S939F]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.127 529 2 0.4% 1 +[F59S]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] XBB.1.5.86 528 225 42.6% 0 (consensus) XBB.1.5.86 528 33 6.2% 1 +[T883I] XBB.1.5.86 528 25 4.7% 1 -[R346T] XBB.1.5.86 528 24 4.5% 2 -[R346T,K417N] XBB.1.5.86 528 22 4.2% 1 +[T676I] B.1.177.69 528 433 82.0% 0 +[A222V,S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] (consensus) B.1.177.69 528 15 2.8% 1 +[A222V,G769V,S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.69 528 13 2.5% 1 +[A222V,A344S,S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] B.1.177.69 528 11 2.1% 1 +[A222V,T385I,S929T]-[T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,