COVID-19 Viral Genome Analysis Pipeline
Enabled by data from
XSpike
eXplore the Spike protein sequence in the SARS CoV-2 virus
Last update: Mar 30, 2023
Delta and Omicron Variants
Global
Wuhan reference
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Evaluating 213784 sequences of length 1670
Sampled from 2023-01-29 to 2023-03-27.
Specified Date Range: ['2023-01-29', '2023-03-30']
Highest entropy sites for: Global
Site Entropy
486 1.1472
146 0.8583
213 0.7494
445 0.7340
183 0.7020
252 0.6985
452 0.6980
83 0.6978
368 0.6927
444 0.6850
490 0.6828
144 0.6706
446 0.6465
339 0.6413
69 0.6142
70 0.6065
257 0.5357
147 0.5193
157 0.4897
152 0.4592
210 0.4306
346 0.3338
460 0.2920
356 0.2125
408 0.1556
185 0.1440
417 0.1276
478 0.1035
248 0.0918
613 0.0903
253 0.0804
477 0.0753
484 0.0686
5 0.0655
883 0.0638
153 0.0626
142 0.0559
245 0.0522
215 0.0517
440 0.0516
1020 0.0491
19 0.0481
182 0.0476
521 0.0469
1162 0.0447
27 0.0437
621 0.0436
24 0.0431
251 0.0422
323 0.0404
Most highly correlated site-pairs for: Global
cramerV mutInfo
213 183 0.3514 0.6645
183 368 0.5723 0.6629
213 368 0.5709 0.6586
445 368 0.5958 0.6577
183 83 0.3737 0.6549
445 183 0.3491 0.6539
83 368 0.5714 0.6528
213 83 0.3730 0.6526
146 183 0.3285 0.6526
213 445 0.3480 0.6491
146 83 0.3717 0.6475
146 213 0.3475 0.6472
146 368 0.5673 0.6468
445 83 0.3718 0.6425
146 445 0.3264 0.6363
27 24 0.7294 0.0375 157 27 0.6306 0.0240 478 477 0.5862 0.0283 452 444 0.5772 0.4200 452 490 0.5669 0.6327 252 368 0.5595 0.6114 477 484 0.5511 0.0229 486 452 0.5488 0.5863 452 446 0.5416 0.3666 157 152 0.5380 0.3941 486 368 0.5235 0.5178 486 356 0.5188 0.1776 452 368 0.5111 0.4430 486 490 0.5105 0.5765 445 444 0.4951 0.3127
Most common patterns for local area, where Local = Global
11
1111111111222222222333334444444444444566801
1226784444555888111445555234560144445677889212826
59479032467237235035581237396688704562078460131302
LTLAHVVGYHKWMFKQNIVDHYPGDGTGRKLRKNKVGLNSTEFFPQPTAP Global UK Eu-UK NAmer Asia Africa SAmer Ocean Local Exact Pct [Context]
213784 28609 59332 84322 31302 1501 1905 6813 137191 <----------- Totals
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 49978 6028 8655 32994 1741 214 41 305 49978 36422 72% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNKT..RKNKAV....... 9861 519 1992 5683 1556 13 31 67 9861 6236 63% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT..SNKT..RKNKAV....... 6243 1014 3005 1701 388 10 17 108 6243 3822 61% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HTT.SNK..S.KNKA.S...... 6109 156 679 281 4852 0 2 139 6109 3351 54% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNKT.SRKNKAS....... 5380 2199 1652 615 683 1 4 226 5380 3167 58% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNK...R.NKAV....... 5040 89 706 433 3782 4 1 25 5040 2657 52% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L..DVG......S.HT..SNKT.SRKNKAS....... 3316 2226 655 150 125 5 3 152 3316 2088 62% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,N185D,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNK...R.NKAV....... 3136 10 119 107 2895 0 0 5 3136 1876 59% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HT..SNK..S.KNKAPS...... 2619 398 589 281 470 0 0 881 2619 1859 70% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-K.....E..E....V...HT.ISNK.PS.KNKAPS...... 2455 242 429 1644 62 3 2 73 2455 1741 70% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146K,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNKT..RKNKAV....... 2221 71 322 1583 214 2 2 27 2221 1009 45% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........D...SNKT..RKNKAV....... 1751 141 605 596 324 2 30 53 1751 884 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........D...SNK...R.NKAV.....S. 1058 0 10 2 1046 0 0 0 1058 771 72% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020S] Omicron_BA.4andBA.5
.I-S--.D..........G......D.DT..SNK...R.NKAV....... 758 0 4 0 754 0 0 0 758 615 81% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G257D,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.IS.K.PS.KNKAPS...... 738 0 382 329 9 0 18 0 738 497 67% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..D.....DT..SNKT..RKNKAV....... 731 93 529 80 17 0 1 11 731 528 72% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248D,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKASS...... 686 38 132 398 109 2 1 6 686 398 58% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-...I.....G........DT..SNKT..RKNKAV....... 652 50 51 516 18 0 0 17 652 284 43% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,M153I,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.I.NK.PS.K.KAPS...... 626 0 626 0 0 0 0 0 626 407 65% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS.H.... 624 81 428 56 32 0 0 27 624 479 76% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..I.......G........DT..SNKT..RKNKAV....... 623 16 222 369 14 0 0 2 623 279 44% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147I,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
FI-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 585 63 77 420 14 3 0 8 585 412 70% [L5F,T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G.....G..DT..SNKT..RKNKAV....... 582 398 120 54 9 0 0 1 582 209 35% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,D253G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,E1144Q] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HT..SNK..SRKNKAI....... 544 22 66 46 66 0 0 344 544 330 60% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,L452R,N460K,S477N,T478K,E484A,F486I,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-....L....G........D...SNKT..RKNKAV....... 540 59 301 167 13 0 0 0 540 375 69% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,F157L,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD.-.....E..E....V...HT.ISNK.PS.KNKAPS...... 538 14 252 197 59 0 0 16 538 359 66% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y145X,H146-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-....L....G........DT..SNKT..RKNKAV....... 536 92 320 114 7 0 0 3 536 286 53% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,F157L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L..DVG......S.HT..SNKT.SRKNKAS..H.... 520 322 62 109 2 0 0 25 520 315 60% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,L176F,N185D,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...I.. 455 85 53 305 7 0 0 5 455 361 79% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNKT.SRKNKAS....I.. 429 244 58 92 5 0 0 30 429 307 71% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K]
.I-S--.D-.........G........D...SNKN..RKNKAV....... 424 34 198 112 74 0 1 5 424 283 66% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNRAPS...... 413 29 27 218 123 0 0 16 413 123 29% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478R,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E........HT.ISNK.PS.KNKAPS...... 398 4 18 364 10 1 1 0 398 234 58% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..E.......G........DT..SNKT..RKNKAV....... 371 34 77 202 56 0 1 1 371 218 58% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147E,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.I.NK.PS.KNKAPS...... 337 0 115 58 85 39 40 0 337 218 64% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V..IHT.ISNK.PS.KNKAPS...... 305 28 175 97 4 0 0 1 305 197 64% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,T323I,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..H.....DT..SNKT..RKNKAV....... 292 21 72 197 1 0 0 1 292 234 80% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248H,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT..SNK...R.NKAV....... 280 10 121 37 108 1 0 3 280 132 47% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..Q.......G........D...SNK..DRKNKAV....... 280 0 0 0 280 0 0 0 280 197 70% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147Q,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446D,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..N.......G........DT..SNKT..RKNKAV....... 271 174 56 25 13 0 0 3 271 120 44% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147N,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT...NKT..RKNKAV....... 247 0 241 2 0 0 4 0 247 121 48% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS..S... 243 14 29 199 1 0 0 0 243 174 71% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNKN..RKNKAV....... 210 7 101 86 14 0 2 0 210 78 37% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K150E,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D....T.....G.N....D.D...SNKR..MKNKR........ 208 3 42 26 134 0 0 3 208 125 60% [T19I,L24-,P25-,P26-,A27S,G142D,M153T,N164K,V213G,H245N,G257D,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,N450D,L452M,N460K,S477N,T478K,E484R,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPSS..... 208 6 168 28 4 0 0 2 208 136 65% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,I410V,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P521S,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E.....G..HT.ISNK.PS.KNKAPSS..... 207 56 41 32 74 0 1 3 207 100 48% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,D253G,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P521S,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNKT..RKNKAV..H.... 201 7 87 91 13 1 2 0 201 163 81% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-QI....E..E....V...HT.ISNK.PS.KNKAPS...... 201 0 1 200 0 0 0 0 201 178 88% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,K147I,Q183E,V213E,G252V,T284I,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNK...R.NKAV....I.. 200 0 2 2 196 0 0 0 200 91 45% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........DT...NKT..RKNKAV....... 185 0 174 6 3 0 2 0 185 106 57% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........DT..S.KT..RKNKAV....... 183 0 169 7 5 0 2 0 183 102 55% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNK...R.NKAV.....S. 182 0 4 1 177 0 0 0 182 160 87% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020S] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HTT.SNK.AS.KNKA.S...... 175 0 2 0 172 0 0 1 175 124 70% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445A,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........D...SNKT..RKNKAA....... 174 5 23 146 0 0 0 0 174 141 81% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486A,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNK..S.KNKAPS.....S 170 0 166 1 3 0 0 0 170 132 77% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S]
.I-S--.D..........G..S.....D...SNKT..RKNKAV....... 166 0 5 158 3 0 0 0 166 59 35% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248S,+248RWMD,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD.Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 165 0 24 125 15 0 0 1 165 124 75% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..S.....DT..SNKT..RKNKAV....... 163 0 137 25 1 0 0 0 163 75 46% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248S,+248AED,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G...L....DT..SNKT..RKNKAV....... 162 22 34 70 6 28 1 1 162 50 30% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,P251L,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
FI-S--.D..........G........DT..SNKT..RKNKAV....... 161 2 22 110 27 0 0 0 161 99 61% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.......D.G........DT..SNKT..RKNKAV....... 156 4 110 8 34 0 0 0 156 66 42% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,N185D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 151 0 89 57 3 2 0 0 151 110 72% [T19I,L24-,P25-,P26-,A27S,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..EH...V...HT.ISNK.PS.KNKAPS...... 150 45 64 31 9 1 0 0 150 107 71% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,D215H,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I.....D-....-.....H...........SNK..SM.NKAP....... 144 1 9 5 67 0 0 62 144 76 52% [T19I,P25S,G142D,Y144-,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,L452M,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N703I,N764K,D796Y,Q954H,N969K]
.I-S--.D......I...G........DT..SNKT..RKNKAV....... 143 0 3 136 4 0 0 0 143 92 64% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K182I,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G.....G..DT..SNKT..RKNKAV....... 142 36 14 54 38 0 0 0 142 98 69% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,D253G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G.N......DT..SNKT..RKNKAV....... 141 4 8 128 1 0 0 0 141 105 74% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,H245N,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT..SNKT..RKNKAV..H.... 136 30 93 10 1 0 0 2 136 103 75% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.H.T.SNK..S.KNKA.S...... 135 5 43 13 71 0 0 3 135 77 57% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N450D,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HTT..NK..S.KNKA.S...... 135 0 34 0 100 0 1 0 135 22 16% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E.....G..HT.ISNK.PS.KNKASS...... 129 4 17 94 5 2 7 0 129 70 54% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,D253G,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L....-......S.HT..SNKT.SRKNKAS....... 124 50 34 3 5 0 0 32 124 80 64% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,+209V,N211G,L212-,V213-,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L..DVG......S.HTT.SNK..S.KNKA.S...... 115 2 32 1 67 0 0 13 115 52 45% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,N185D,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,S494P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VGG.....S.HT..SNKT.SRKNKAS..H.... 115 16 29 7 0 0 0 63 115 71 61% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,D215G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-....S....G........DT..SNKT..RKNKAV....... 111 1 7 103 0 0 0 0 111 99 89% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,F157S,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D.....L....G........DT..SNK...R.NKAV....... 110 0 0 2 108 0 0 0 110 78 70% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,F157L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........DT..S.KT..RKNKAV....... 107 0 93 11 0 0 3 0 107 56 52% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........D...SNK...R.NKAV....... 106 3 16 6 81 0 0 0 106 56 52% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L....-......S.HTT.SNK..S.KNKA.S...... 105 42 42 11 9 0 0 1 105 37 35% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,M177T,+209V,N211G,L212-,V213-,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,H1101Y]
.I-S..AD-Q.....E..E........HT.I........NKAPS...... 105 0 4 101 0 0 0 0 105 41 39% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D.-........G........DT..SNKT..RKNKAV....... 104 5 28 67 4 0 0 0 104 76 73% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,H146-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I.....D-....-.....H........S..SNK..SR.NKAP....... 102 0 0 0 0 0 0 102 102 87 85% [T19I,P25S,G142D,Y144-,E156G,F157-,R158-,P209L,L212S,D215H,A222V,A243-,L244-,S256L,R346S,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,L452R,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N703I,N764K,D796Y,Q954H,N969K]
FI-S--.D-.........G........DT..SNKT..RKNKAV....... 101 20 50 20 9 0 0 2 101 55 54% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..A.-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 98 0 61 31 0 1 5 0 98 71 72% [T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNKT.SRKNKAS..H.... 97 12 77 4 0 0 0 4 97 36 37% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,D867N,Q954H,N969K]
.I-S...D..ER.L...VG......-.HT..SNKT.SRKNKAS....... 94 47 13 16 6 0 0 12 94 53 56% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,+254P,G257-,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNK.A.R.NKAV....... 93 0 40 26 22 1 0 4 93 41 44% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445A,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D....T.....G.N....D.D...SNKR.SMKNKRS....... 91 0 3 61 18 0 0 9 91 54 59% [T19I,L24-,P25-,P26-,A27S,G142D,M153T,N164K,V213G,H245N,G257D,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,G446S,N450D,L452M,N460K,S477N,T478K,E484R,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.LN..VG......S.HT..SNKT.SRKNKAS....... 91 53 35 2 1 0 0 0 91 58 63% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,K182N,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........DT..SNKT..RKNKAV....I.. 88 19 41 24 4 0 0 0 88 65 73% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E.Y..V...HT.ISNK.PS.KNKAPS...... 87 3 25 47 8 3 0 1 87 69 79% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,H245Y,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.H...SNKT.SRKNKA........ 87 0 1 1 85 0 0 0 87 64 73% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,Q498R,N501Y,Y505H,D574V,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..-.....DT..SNKT..RKNKAV..H.... 86 2 82 0 2 0 0 0 86 65 75% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,+246N,Y248-,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG........HTT.SNK..S.KNKA.S...... 85 0 3 0 82 0 0 0 85 28 32% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNK.A.R.NKAV....... 83 0 8 28 47 0 0 0 83 49 59% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445A,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........D...SNKM..R.NKAV....... 83 0 1 5 77 0 0 0 83 38 45% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444M,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D.-........G........D...SNKT..RKNKAV....... 82 5 32 45 0 0 0 0 82 35 42% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,H146-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E...SV...HT.ISNK.PS.KNKAPS...... 81 31 34 16 0 0 0 0 81 55 67% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,P251S,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNKT.SRKNKAS...S... 81 64 5 10 1 0 0 1 81 67 82% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D--........G........DT..SNKT..RKNKAV....... 79 2 17 59 1 0 0 0 79 52 65% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,H146-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT..SNKT..RKNKAV......S 77 5 7 62 3 0 0 0 77 58 75% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPST..... 75 0 10 63 2 0 0 0 75 33 44% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P521T,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DS..SNK...R.NKAV....... 75 1 21 24 29 0 0 0 75 49 65% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346S,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..A.-Q.....E..E....V...HT.IS.K.PS.KNKAPS...... 74 0 68 6 0 0 0 0 74 61 82% [T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S--.D..........G........DT..SNK...R.NKAV....... 73 7 13 4 48 0 0 1 73 31 42% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.I........NKAPS...... 72 0 0 72 0 0 0 0 72 54 75% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G.Y......DT..SNKT..RKNKAV....... 71 9 14 42 6 0 0 0 71 47 66% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,H245Y,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..E.......G........D...SNKT..RKNKAV....... 71 1 51 10 6 0 0 3 71 56 78% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147E,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT..SNKR..R.NKAV....... 71 17 34 13 7 0 0 0 71 22 30% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.......D.G........DT..SNKT..RKNKAV..H.... 71 47 16 2 3 1 0 2 71 55 77% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,N185D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........DT..SNKT..RKNKAV....I.. 70 15 19 11 24 0 1 0 70 57 81% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-....L....G........DT..SNKT..RKNKAV..H.... 69 0 6 60 2 0 1 0 69 49 71% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,F157L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........DT...NK...R.NKAV....... 69 0 67 1 1 0 0 0 69 48 69% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-......E..E....V...HT.ISNK.PS.KNKAPS...... 68 3 21 36 7 0 0 1 68 36 52% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D.-........G........D...SNKTA.RKNKAV..H.... 66 60 2 2 1 0 0 1 66 29 43% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y145L,H146-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,V445A,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,I770M,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.L-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 65 4 13 48 0 0 0 0 65 48 73% [T19L,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNK..S.KNKAPS..S... 64 31 0 0 1 0 0 32 64 28 43% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G.....G..DT..SNKT..RKNKAV......S 64 57 7 0 0 0 0 0 64 52 81% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,D253G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,E1144Q,P1162S] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS.....L 63 18 9 33 3 0 0 0 63 27 42% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162L]
.I-S--.D..........G........DT..SNKT..RKNRAV....... 61 0 6 39 9 5 0 2 61 28 45% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478R,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........DT..SNK.A.R.NKAV....... 60 0 7 40 13 0 0 0 60 42 70% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,A262S,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445A,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..E...N...G........DT..SNKT..RKNKAV....... 59 36 23 0 0 0 0 0 59 49 83% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147E,K182N,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT..SNKRA.R.NKAV....... 59 0 6 28 24 0 0 1 59 45 76% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,P209L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,V445A,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
FI-S...D..ER.L...VG......S.HTT.SNK..S.KNKA.S...... 58 1 10 1 40 0 1 5 58 26 44% [L5F,T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..-L....DT..SNKT..RKNKAV....... 58 5 52 0 0 0 0 1 58 37 63% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,+246N,Y248-,P251L,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G......-.DT..SNKT..RKNKAV....... 58 53 3 1 1 0 0 0 58 43 74% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,+255P,G257-,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKASS...I.. 57 2 40 12 2 1 0 0 57 27 47% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K]
.I-S..AD-Q...L.E..E....V...HT.ISNK.PS.KNKAPS...... 57 8 5 38 6 0 0 0 57 37 64% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,F157L,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNKTA.RKNKAV....... 57 3 17 33 0 0 0 4 57 33 57% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,V445A,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
FI-S--.D-.........G........D...SNKT..RKNKAV....... 55 0 16 13 23 0 0 3 55 23 41% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,I666V,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HT..SNKT..RKNKAV....... 55 33 16 5 1 0 0 0 55 33 60% [T19I,L24-,P25-,P26-,A27S,D111N,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,T678I,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK..S.KNKAPS...... 54 0 0 54 0 0 0 0 54 41 75% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D.L........G........D...SNKT..RKNKAV....... 54 0 7 43 4 0 0 0 54 40 74% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,H146L,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......SAHT..SNKT.SRKNKAS....... 53 31 18 1 3 0 0 0 53 42 79% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,T323A,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D.....L....G........DT..SNKT..RKNKAV....... 53 1 6 42 4 0 0 0 53 16 30% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,F157L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........GY.......DT..SNKT..RKNKAV....... 53 1 3 49 0 0 0 0 53 42 79% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,D215Y,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,V1264L] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.K....S...... 53 0 0 53 0 0 0 0 53 41 77% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..N.......G........DT..SNK...R.NKAV....... 52 20 19 7 6 0 0 0 52 32 61% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147N,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..-.......G........D...SNK...R.NKAV......S 52 0 52 0 0 0 0 0 52 37 71% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147-,N149-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S] Omicron_BA.4andBA.5
.I-S--.D-.........G........DS..SNKT..RKNKAV....... 51 15 25 10 1 0 0 0 51 27 52% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346S,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........D....NKT..RKNKAV....... 51 0 48 0 1 0 2 0 51 21 41% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.R.....D...L.-....G.....G..DT..SNK..DR.NKAP...S... 50 1 49 0 0 0 0 0 50 18 36% [L18F,T19R,R21G,T95I,G142D,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446D,L452R,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,A706V,N764K,D796Y,Q954H,N969K,T1117I,D1153Y]
.I-S--.D......E...G...L....DT..SNKT..RKNKAV......L 49 0 6 41 2 0 0 0 49 39 79% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K182E,V213G,Q218H,P251L,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162L] Omicron_BA.4andBA.5
.I.-..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 48 8 7 29 2 0 0 2 48 34 70% [T19I,P25-,P26-,A27-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD.K.....E..E....V...HT.ISNK.PS.KNKAPS...... 47 0 7 37 2 0 0 1 47 18 38% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,H146K,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........D...SNKM..RKNKAV....... 47 6 14 17 10 0 0 0 47 24 51% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444M,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
FI-S...D..ER.L...VG......S.HT..SNK..S.KNKAPS...... 47 2 7 0 3 0 0 35 47 37 78% [L5F,T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNK...R.NKAV....... 47 0 46 1 0 0 0 0 47 38 80% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNK..SRKNKAS....... 47 11 23 6 7 0 0 0 47 17 36% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-K.....E..E....V...HT.I.NK.PS.K.KAPS...... 47 0 47 0 0 0 0 0 47 32 68% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146K,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS.....S 46 6 5 35 0 0 0 0 46 32 69% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S]
.I-S..AD-K.....E..E....V...HT.IS.K.PS.KNKAPS...... 45 0 28 15 0 0 2 0 45 28 62% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146K,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G...L....DT..SNKT..RKNRAV....... 45 0 31 0 0 11 0 3 45 28 62% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,P251L,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478R,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,N856S,Q954H,N969K]
.I-S--.D--........G........D...SNK...R.NKAV....... 44 4 13 0 27 0 0 0 44 20 45% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,H146-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--FD..........G........DT..SNK...R.NKAV....... 44 0 0 0 44 0 0 0 44 26 59% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,V83F,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,C1243F] Omicron_BA.4andBA.5
.I-S--.D..I.......G........D...SNKT..RKNKAV....... 43 1 29 12 1 0 0 0 43 12 27% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147I,V213G,S255F,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
FI-S...D..ER.L..DVG......S.HT..SNKT.SRKNKAS....... 43 39 2 0 1 0 0 1 43 29 67% [L5F,T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,N185D,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--..-.........G........DT..SNKT..RKNKAV....... 43 0 41 0 0 0 2 0 43 24 55% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.V-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 42 0 1 40 0 0 0 1 42 38 90% [T19V,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNKM.SRKNKAS....... 42 6 1 23 5 0 0 7 42 21 50% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444M,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,D1199N]
.I-S..AD-Q.....E..E....V...HI.ISNK.PS.KNKAPS...... 42 0 4 37 1 0 0 0 42 28 66% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346I,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNKT..RKNKAA....... 41 3 12 18 6 2 0 0 41 25 60% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486A,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........DT...NKT..RK.KAV....... 41 0 41 0 0 0 0 0 41 19 46% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HTT.S.K..S.KNKA.S...... 40 0 7 1 32 0 0 0 40 15 37% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........DT..SNKT..RKNRAV....... 39 1 3 32 2 1 0 0 39 30 76% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478R,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ERIL...VG......S.HTT.SNK..S.KNKA.S...... 39 0 3 22 14 0 0 0 39 32 82% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,M153I,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT...NKT.SRKNKAS....... 39 0 27 0 12 0 0 0 39 16 41% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--............G........DT..SNKT..RKNKAV....... 39 0 33 2 4 0 0 0 39 23 58% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HT..SNKT.SRKNKA........ 39 21 6 1 9 0 0 2 39 27 69% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D....NKN..RKNKAV....... 39 0 37 0 1 0 1 0 39 32 82% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K150E,V213G,G339D,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E.....G..HT.ISNK.PS.KNKAPS...... 38 7 26 3 2 0 0 0 38 20 52% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,D253G,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISN..PS.KNKAPS...... 38 0 18 20 0 0 0 0 38 25 65% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS....V. 37 4 3 30 0 0 0 0 37 27 72% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020V]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNIAPS...... 37 6 0 31 0 0 0 0 37 32 86% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478I,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S--.D..........G........D...SNKT..RKNKAV....... 37 0 3 29 4 0 0 1 37 9 24% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..N.T.....G.N....D.D...SNKR.SMKNKRS....... 37 0 0 2 35 0 0 0 37 29 78% [T19I,L24-,P25-,P26-,A27S,G142D,K147N,M153T,N164K,V213G,H245N,G257D,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,G446S,N450D,L452M,N460K,S477N,T478K,E484R,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HTT.SNK..S.KNKASS...... 37 14 18 4 1 0 0 0 37 19 51% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
..-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 37 1 16 18 1 0 0 1 37 19 51% [L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNK..DR.NKAV....... 37 0 0 0 37 0 0 0 37 25 67% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446D,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.....E...G...L....DT..SNKT.RRKNKAV....... 36 36 0 0 0 0 0 0 36 28 77% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,K182E,V213G,P251L,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446R,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L.P.VG......S.HT..SNKT.SRKNKAS....... 36 8 1 0 27 0 0 0 36 31 86% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,Q183P,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..D.....DT...NKT..RKNKAV....... 36 0 36 0 0 0 0 0 36 20 55% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248D,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........D....NKN..RKNKAV....... 36 0 34 0 0 0 2 0 36 24 66% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-SY.AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 35 3 4 28 0 0 0 0 35 27 77% [T19I,L24-,P25-,P26-,A27S,H69Y,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPP...... 35 5 5 25 0 0 0 0 35 16 45% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISN......NKAPS...... 35 0 0 35 0 0 0 0 35 17 48% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-....L....G........D...SNKN..RKNKAV....... 35 2 1 29 1 0 0 2 35 26 74% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,F157L,G181V,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.K........... 34 0 5 25 4 0 0 0 34 9 26% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G.Y......DT..SNKT..RKNKAV....... 34 6 14 12 2 0 0 0 34 22 64% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,H245Y,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G...S....D...SNK...R.NKAV....... 34 0 0 0 34 0 0 0 34 28 82% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,P251S,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........DT..SNK...R.NRAV....... 34 9 5 1 6 13 0 0 34 17 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478R,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,T747I,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E........HT.ISNK.PS.KNKASS...... 33 0 10 16 4 2 0 1 33 7 21% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S--.D..........G........D...SNK...R.NKAV....... 33 0 3 0 30 0 0 0 33 24 72% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.L-S--.D..........G........DT..SNK...R.NKAV....... 33 1 1 0 31 0 0 0 33 24 72% [T19L,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D...L......G........D...SNKT..RKNKAV....... 33 0 0 32 0 0 0 1 33 13 39% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,W152L,V213G,S256L,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,E619K,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........D...S.KT..RKNKAV....... 32 0 30 2 0 0 0 0 32 18 56% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNKTA.RKNKAV....... 32 1 1 30 0 0 0 0 32 26 81% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,V445A,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S.............VG......S.HTT.SNK..S.KNKA.S...... 32 0 0 0 32 0 0 0 32 18 56% [T19I,L24-,P25-,P26-,A27S,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.I..K.PS.KNKAPS...... 32 0 16 14 2 0 0 0 32 9 28% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D.-........G........D...SNKT..RKNKAV..H.... 32 28 4 0 0 0 0 0 32 15 46% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y145L,H146-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........D...SN....R.NKAV....... 32 0 29 1 2 0 0 0 32 23 71% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,A260X,G261X,A262X,A263X,A264X,Y265X,Y266X,V267X,G268X,Y269X,L270X,Q271X,P272X,R273X,T274X,F275X,L276X,L277X,K278X,Y279X,N280X,E281X,N282X,G283X,T284X,I285X,T286X,D287X,A288X,V289X,D290X,C291X,A292X,L293X,D294X,P295X,L296X,S297X,E298X,T299X,K300X,C301X,T302X,L303X,K304X,S305X,F306X,T307X,V308X,E309X,K310X,G311X,I312X,Y313X,Q314X,T315X,S316X,N317X,F318X,R319X,V320X,Q321X,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DI..SNK...R.NKAV....... 31 1 8 6 16 0 0 0 31 25 80% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......-.HTT.SNK..S.KNKA.S...... 31 0 5 1 25 0 0 0 31 11 35% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,+255L,G257-,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNKT..RKNKAV...H... 31 0 4 27 0 0 0 0 31 26 83% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,P621H,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D......E...G...L....DT..SNKT..RKNKAV..H...L 31 2 24 0 0 0 0 5 31 18 58% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K182E,V213G,Q218H,P251L,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162L] Omicron_BA.4andBA.5
.I-S..AD-K.....E..E....V...HT.ISNK.PS.KNKASS...... 30 0 4 14 10 0 2 0 30 17 56% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146K,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E.....-..HT.ISNK.PS.KNKAPS...... 30 0 0 28 2 0 0 0 30 27 90% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,+251V,D253-,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNKT..RKNKAV...S... 30 1 8 21 0 0 0 0 30 19 63% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HT..SNK..N.KNKAPS...... 30 0 1 0 2 0 0 27 30 27 90% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446N,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D......E...G........DT..SNKT..RKNKAV....... 30 6 16 6 1 1 0 0 30 23 76% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K182E,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS..NKAPS...... 30 0 16 13 1 0 0 0 30 22 73% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..........NKAV....... 30 0 0 30 0 0 0 0 30 15 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....................NKAPS...... 30 0 0 30 0 0 0 0 30 14 46% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..EG...V...HT.ISNK.PS.KNKAPS...... 29 7 4 18 0 0 0 0 29 24 82% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,D215G,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.SS.KNKAPS...... 29 6 17 3 3 0 0 0 29 19 65% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445S,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G.....G..D...SNKT..RKNKAV....... 29 0 9 5 15 0 0 0 29 13 44% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,D253G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,I666V,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L..DVG......S.HT..SNKT.SRKNKAS....I.. 29 1 0 1 0 0 0 27 29 25 86% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,N185D,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKASP...... 29 3 7 1 16 0 0 2 29 14 48% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D...R......G........DT..SNKT..RKNKAV....... 29 1 4 21 1 2 0 0 29 23 79% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,W152R,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........D....NK...R.NKAV....... 29 0 18 0 11 0 0 0 29 6 20% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT...NKT..RK.KAV....... 29 0 29 0 0 0 0 0 29 12 41% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,N969K]
.I-S--.D-...IL....G........DT..SNKT..RKNKAV....... 28 0 28 0 0 0 0 0 28 21 75% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,M153I,F157L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,V1264L] Omicron_BA.4andBA.5
FI-S...D..ER.L...VG......S.HT..SNKT.SRKNKAS....... 28 10 10 2 2 0 0 4 28 22 78% [L5F,T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.R...E..E....V...HT.ISNK.PS.KNKAPS...... 28 2 9 16 1 0 0 0 28 25 89% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,W152R,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..ADQ-.....E..E....V...HT.ISNK.PS.KNKAPS...... 28 2 11 14 1 0 0 0 28 17 60% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,V143D,Y144Q,Y145-,H146-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-SY..D..ER.L..DVG......S.HT..SNKT.SRKNKAS....... 28 28 0 0 0 0 0 0 28 27 96% [T19I,L24-,P25-,P26-,A27S,H69Y,G142D,K147E,W152R,F157L,N185D,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,I569V,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT..SNK.PS.KNKAPS...... 27 0 23 3 1 0 0 0 27 10 37% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......SIHT..SNK..S.KNKAPS...... 27 21 5 1 0 0 0 0 27 25 92% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,T323I,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..FD..ER.L...VG......S.HTT.SNK..S.KNKA.S...... 27 0 0 0 27 0 0 0 27 26 96% [T19I,L24-,P25-,P26-,A27S,V83F,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..A--Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 27 4 2 20 1 0 0 0 27 19 70% [T19I,L24-,P25-,P26-,A27S,V83A,L141-,G142-,V143-,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..D.....DT..SNKT..RKNKAV......S 27 0 27 0 0 0 0 0 27 8 29% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248D,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S] Omicron_BA.4andBA.5
.I-S--.D..........G.......IDT..SNKT..RKNKAV....... 27 4 5 10 1 0 0 7 27 16 59% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,T323I,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.......T.G........DT..SNKT..RKNKAV....... 27 4 16 6 1 0 0 0 27 13 48% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,N185T,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,E471Q,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ERIL...VG......S.HT..SNKT.SRKNKAS....... 26 10 2 8 5 0 0 1 26 16 61% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,M153I,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S..AD-K.....E..E....V...HT.ISNK.PS.KNKAPS...... 26 7 5 14 0 0 0 0 26 22 84% [L5F,T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146K,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISSK.PS.KNKAPS...... 26 5 20 1 0 0 0 0 26 25 96% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-SF-.D..........G........DT..SNKT..RKNKAV....... 26 0 3 22 1 0 0 0 26 18 69% [T19I,L24-,P25-,P26-,A27S,H69F,V70-,S71-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........D....NKT..RKNKAV....... 26 0 26 0 0 0 0 0 26 9 34% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........D...SNKT..RKNRAV....... 25 2 1 12 9 0 0 1 25 15 60% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478R,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,I666V,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-SF-.D..........G........D...SNKN..RKNKAV....... 25 1 22 0 2 0 0 0 25 15 60% [Q14H,T19I,L24-,P25-,P26-,A27S,H69F,V70-,S71-,G142D,K150E,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD.-.....E..E....V...HT.ISNK.PS.KNKAPS.H.... 25 1 23 0 0 0 0 1 25 23 92% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y145X,H146-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........DT..SNKT..R.NKAV....... 25 0 23 2 0 0 0 0 25 14 56% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..........G..N.....DT..SNK...R.NKAV.....S. 25 0 1 24 0 0 0 0 25 20 80% [T19I,L24-,P25-,P26-,A27S,G142D,V213G,Y248N,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,T547I,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020S] Omicron_BA.4andBA.5
.L-S--.D..........G........DT..SNKT..RKNKAV....... 25 1 5 3 16 0 0 0 25 8 32% [T19L,L24-,P25-,P26-,A27S,H69-,V70-,G142D,L176F,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HTT.SNK..S.KNRA.S...... 24 0 6 0 18 0 0 0 24 21 87% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478R,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.......Y.G........DT..SNKT..RKNKAV....... 24 0 6 18 0 0 0 0 24 20 83% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,N185Y,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HT..S.KT.SRKNKAS....... 24 0 23 0 1 0 0 0 24 14 58% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNKT..RKNKAV......L 24 0 11 13 0 0 0 0 24 17 70% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162L] Omicron_BA.4andBA.5
.I-S--.D..........G........DT..SNKT..RKNQAV....... 24 0 0 22 0 2 0 0 24 17 70% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478Q,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E........HT.I................... 24 0 2 22 0 0 0 0 24 4 16% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VE......S.HT..SNKT.SRKNKAS....... 24 22 2 0 0 0 0 0 24 18 75% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213E,G257S,G339H,R346T,A348S,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..ADK-.....E..E....V...HT.ISNK.PS.KNKAPS...... 23 0 23 0 0 0 0 0 23 11 47% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144K,Y145-,H146-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNKT..RKNKAV...S... 23 0 1 21 1 0 0 0 23 12 52% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,P621S,H655Y,I666V,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HT..SNK..SRKNKA........ 23 0 2 0 4 0 0 17 23 16 69% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,L452R,N460K,S477N,T478K,E484A,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNK.AS.KNKAPS...... 23 4 6 6 7 0 0 0 23 8 34% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445A,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D........D.G........DT..SNKT..RKNKAV....... 23 1 3 5 13 0 0 1 23 19 82% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,N185D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.R.....D...L.-....G........D...SNK..DR.NKAP...S... 23 0 22 1 0 0 0 0 23 16 69% [L18F,T19R,R21G,T95I,G142D,W152L,E156G,F157-,R158-,F186L,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446D,L452R,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,A706V,N764K,D796Y,Q954H,N969K,T1117I]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKA.S...... 23 0 7 14 2 0 0 0 23 16 69% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........DT...NK...R.NKAV....... 23 0 23 0 0 0 0 0 23 12 52% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G...H....D...SNKT..RKNKAV....... 23 1 4 18 0 0 0 0 23 10 43% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,P251H,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I.---AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 23 0 0 0 23 0 0 0 23 21 91% [T19I,P25-,P26-,A27-,H69-,V70-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D...L......G........DT..SNKT..RKNKAV....... 22 0 11 11 0 0 0 0 22 14 63% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,W152L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VE......S.HTT.SNK..S.KNKA.S...... 22 0 5 0 17 0 0 0 22 14 63% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213E,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNKT..RKNKAV......S 22 0 5 17 0 0 0 0 22 16 72% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S] Omicron_BA.4andBA.5
.R.....D...L.-....G.....G..DT...NK..DR.NKAP...S... 22 0 22 0 0 0 0 0 22 12 54% [L18F,T19R,R21G,T95I,G142D,W152L,E156G,F157-,R158-,F186L,V213G,D253G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,G446D,L452R,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,A706V,N764K,D796Y,Q954H,N969K,T1117I,D1153Y]
.I-S..AD-Q.....E..E....V...HT.IGNK.PS.KNKAPS...... 22 0 18 4 0 0 0 0 22 21 95% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408G,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...DT.ISNK.PS.KNKAPS...... 22 0 22 0 0 0 0 0 22 13 59% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339D,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...D...SNK.PS.KNKAPS...... 21 0 21 0 0 0 0 0 21 7 33% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-K.....E..E........HT.ISNK.PS.KNKAPS...... 21 0 7 14 0 0 0 0 21 14 66% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146K,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HTT.SNK..S.KNKA.S.....L 21 1 0 1 19 0 0 0 21 15 71% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162L]
.I-S--.D-.........G........D...SNKT..RKNKAV..H.... 21 8 4 6 1 0 0 2 21 6 28% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........DT..SN....R.NKAV....... 21 0 14 2 5 0 0 0 21 8 38% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........DT..SNK...R.NKAV....I.. 21 0 8 10 3 0 0 0 21 14 66% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K] Omicron_BA.4andBA.5
.I-S......ER.L...VG......S.HTT.SNK..S.KNKA.S...... 21 0 19 0 2 0 0 0 21 10 47% [T19I,L24-,P25-,P26-,A27S,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S--.D-.........G........DT...NKT..RKNKAV....... 21 0 21 0 0 0 0 0 21 13 61% [L5F,L8F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,E554V,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..ER.L...VG......S.HTT.SNK..S.KNKA.S...... 20 0 0 1 19 0 0 0 20 11 55% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT...NK..S.KNKAPS...... 20 0 10 0 10 0 0 0 20 8 40% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..EQ.L...VG......S.HT..SNK..S.KNKAPS...... 20 3 5 1 4 0 0 7 20 9 45% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152Q,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......SKHT..SNKT.SRKNKAS....... 20 18 0 0 0 0 0 2 20 16 80% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,T323K,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.......I.G........DT..SNKT..RKNKAV....... 20 16 3 0 1 0 0 0 20 17 85% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,N185I,F186-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KN.APS...... 20 2 2 15 1 0 0 0 20 10 50% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........NT..SNKT..RKNKAV....... 20 2 0 18 0 0 0 0 20 16 80% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339N,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKASP...... 20 0 0 20 0 0 0 0 20 16 80% [L5F,T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D.......P..G........DT..SNK...R.NKAV....... 20 0 0 0 20 0 0 0 20 19 95% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Q183P,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT..SNKT..RKNKAA....... 19 6 7 3 1 2 0 0 19 6 31% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486A,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G.N......DT..SNKT..RKNKAV....... 19 18 0 1 0 0 0 0 19 18 94% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,T208M,V213G,H245N,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L..DVG......SIHT..SNKT.SRKNKAS....... 19 18 1 0 0 0 0 0 19 14 73% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,N185D,I210V,V213G,G257S,T323I,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D.NER.L...VG......S.HTT.SNK..S.KNKA.S...... 19 0 3 0 16 0 0 0 19 11 57% [T19I,L24-,P25-,P26-,A27S,G142D,H146N,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q........E....V...HT.ISNK.PS.KNKAPS...... 19 1 8 7 1 1 1 0 19 9 47% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D...L......G........D...SNK...R.NKAV....... 19 0 0 1 18 0 0 0 19 5 26% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,W152L,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........DT..SNKT..R.NKAV....... 19 0 16 2 1 0 0 0 19 13 68% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E............................... 19 0 2 17 0 0 0 0 19 8 42% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E......S.HT.ISNK.PS.KNKAPS...... 18 6 4 8 0 0 0 0 18 7 38% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G257S,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D--........G........D...SNKT..RKNKAV....... 18 0 1 16 0 0 0 1 18 12 66% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,H146-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.--.........G........DT..SNKT..RKNKAV....... 18 1 9 5 2 0 0 1 18 3 16% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,P139-,F140-,L141-,G142-,V143-,Y144-,Y145-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..A---.....E..E....V...HT.ISNK.PS.KNKAPS...... 18 1 6 11 0 0 0 0 18 6 33% [T19I,L24-,P25-,P26-,A27S,V83A,D138Q,P139-,F140-,L141-,G142-,V143-,Y144-,Y145-,H146-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S--.D..E.......G........DT..SNKT..RKNKAV....... 18 2 1 15 0 0 0 0 18 13 72% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147E,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.IS.K.PS.KNKAPS.H.... 18 0 18 0 0 0 0 0 18 17 94% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E.....G..HT.ISNK.PS.KNKASS.H.... 18 0 2 11 5 0 0 0 18 11 61% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,D253G,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G....D...DT..SNKT..RKNKAV....... 18 2 2 8 5 0 0 1 18 12 66% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G252D,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.K.NAPS...... 18 0 3 15 0 0 0 0 18 13 72% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,G476-,T478N,+478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D.-........G........D....NKT..RKNKAV....... 18 0 18 0 0 0 0 0 18 8 44% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,H146-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-SF-.D-.........G........DT..SNKT..RKNKAV....... 18 4 12 2 0 0 0 0 18 11 61% [T19I,L24-,P25-,P26-,A27S,H69F,V70-,S71-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.I................... 18 0 0 18 0 0 0 0 18 10 55% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D........D.G........DT..SNK...R.NKAV....... 18 0 1 0 17 0 0 0 18 12 66% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,N185D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-...V.....G........DT..SNKT..RKNKAV....... 18 2 9 7 0 0 0 0 18 16 88% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,M153V,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT..SNKTA.RKNKAV....... 17 1 2 14 0 0 0 0 17 9 52% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,V445A,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G........DT..SNKT..RKNKAV...S... 17 4 8 3 0 1 0 1 17 11 64% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 17 0 6 9 1 1 0 0 17 10 58% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNK.AS.KNKA........ 17 0 0 0 17 0 0 0 17 11 64% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445A,G446S,N460K,S477N,T478K,E484A,Q498R,N501Y,Y505H,D574V,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...H..ISNK.PS.KNKAPS...... 17 1 9 0 0 0 6 1 17 12 70% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-...I.....G........DT..SNKT..RKNKAV....I.. 17 12 0 4 0 0 0 1 17 14 82% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,M153I,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAAS...... 17 0 12 4 1 0 0 0 17 11 64% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G......D.DT..SNKT..RKNKAV....... 17 1 5 7 4 0 0 0 17 9 52% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G257D,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G.....Y..DT..SNKT..RKNKAV....... 17 0 0 17 0 0 0 0 17 14 82% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,D253Y,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S......ER.L...VG......S.HT..SNKT.SRKNKAS....... 17 0 17 0 0 0 0 0 17 11 64% [T19I,L24-,P25-,P26-,A27S,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.IS.K.PS.K........... 17 0 0 17 0 0 0 0 17 11 64% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S......ER.LN..VG......S.HT..SNKT.SRKNKAS....... 17 0 17 0 0 0 0 0 17 10 58% [T19I,L24-,P25-,P26-,A27S,K147E,W152R,F157L,K182N,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-K.....E..E....V...HT.I.NK.PS.KNKAPS...... 16 0 6 3 5 1 1 0 16 11 68% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146K,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HTTISNK.PS.KNKAPS...... 16 2 3 11 0 0 0 0 16 11 68% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,K356T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L....G........DT..SNKT..RKNKAV....... 16 4 1 8 3 0 0 0 16 14 87% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....I...HT.ISNK.PS.KNKAPS...... 16 0 1 15 0 0 0 0 16 12 75% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252I,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNKT..R.NKAV....... 16 0 3 3 10 0 0 0 16 13 81% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L.R.VG......S.HTT.SNK..S.KNKA.S...... 16 0 0 0 16 0 0 0 16 11 68% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,Q183R,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.IS.K.PS.KNKASS...... 16 0 3 12 0 0 1 0 16 6 37% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNK...R.NKAV......S 16 0 1 0 15 0 0 0 16 10 62% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S] Omicron_BA.4andBA.5
.I-S--.D-Q.....E..E....V...HT.ISNK.PS.KNKAPS...... 16 0 14 1 1 0 0 0 16 12 75% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-....L....G........D...S.KT..RKNKAV....... 16 0 16 0 0 0 0 0 16 15 93% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,F157L,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-...V...D.G........DT..SNKT..RKNKAV....... 16 0 16 0 0 0 0 0 16 11 68% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,M153V,N185D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,G946R,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D....T.....G.N....D.D...SNKRA.MKN.R........ 16 0 3 5 6 0 0 2 16 8 50% [T19I,L24-,P25-,P26-,A27S,G142D,M153T,N164K,V213G,H245N,G257D,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,V445A,N450D,L452M,N460K,S477N,E484R,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...........NKAV....... 16 0 1 15 0 0 0 0 16 3 18% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S......ER.L...VG......S.HT..SNK..S.KNKAPS...... 16 0 16 0 0 0 0 0 16 15 93% [T19I,L24-,P25-,P26-,A27S,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.I.NK.PS.K.KAPS.H.... 16 0 16 0 0 0 0 0 16 10 62% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V.......................... 16 0 0 16 0 0 0 0 16 6 37% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,D614G,H655Y,N679K,P681H,D796Y,Q954H,N969K]
.I-S...D..ER.L..SVG......S.HTT.SNK..S.KNKA.S...... 15 0 1 8 6 0 0 0 15 13 86% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,N185S,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VGG.....S.HTT.SNK..S.KNKA.S...... 15 4 0 0 10 0 0 1 15 7 46% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,D215G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG.Y....S.HTT.SNK..S.KNKA.S...... 15 0 11 0 2 0 0 2 15 10 66% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,H245Y,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S--.D..........G......D.DT..SNK...R.NKAV....... 15 0 0 0 15 0 0 0 15 7 46% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G257D,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
FI-S--.D..........G........D...SNK...R.NKAV.....S. 15 0 0 0 15 0 0 0 15 8 53% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,T76I,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020S] Omicron_BA.4andBA.5
.I-S--.D..........G........D...SNKM..RKNKAV....... 15 1 8 6 0 0 0 0 15 6 40% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444M,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,I666V,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........D...SNKN..RKNKAV......L 15 2 13 0 0 0 0 0 15 7 46% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K150E,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162L] Omicron_BA.4andBA.5
.I-S--.D..........G........DT..SNK...RYNKAV....... 15 0 12 1 2 0 0 0 15 14 93% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,N460Y,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L..DVG......S.HT..SNKT.SRKNKAS...S... 15 12 3 0 0 0 0 0 15 15 100% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,N185D,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HT..SNKT.SRKNKAS......S 15 10 2 0 2 0 0 1 15 8 53% [T19I,L24-,P25-,P26-,A27S,W64R,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S]
.I-S..AD-Q.....E..E....V...HT.ISNKRPS.KNKAPS...... 15 0 11 4 0 0 0 0 15 9 60% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,K1255R]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS....D. 15 0 1 14 0 0 0 0 15 13 86% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020D]
.I-S...D..ER.L.H.VG......S.HTT.SNK..S.KNKA.S...... 14 0 2 0 12 0 0 0 14 11 78% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,Q183H,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G...T....D...SNK...R.NKAV....... 14 0 0 0 14 0 0 0 14 12 85% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,P251T,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D....T.....G.NH...D.D...SNKR..MKNKR........ 14 0 0 0 14 0 0 0 14 8 57% [T19I,L24-,P25-,P26-,A27S,G142D,M153T,N164K,V213G,H245N,Y248H,G257D,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,N450D,L452M,N460K,S477N,T478K,E484R,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S...D..ER.L...VG......S.HT..SNKT.SRKNKAS....I.. 14 1 10 3 0 0 0 0 14 9 64% [L5F,T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K]
.I-S--.D-.........G......S.D...SNKN..RKNKAV....... 14 1 13 0 0 0 0 0 14 9 64% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G257S,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G.Y......D...SNKT..RKNKAV....... 14 0 0 10 4 0 0 0 14 9 64% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,H245Y,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..E.......G........DT..SNK.A.R.NKAV....... 14 0 14 0 0 0 0 0 14 14 100% [V3G,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147E,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445A,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D......I...G........DT..SNKT..RKNKAV......L 14 0 0 14 0 0 0 0 14 13 92% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K182I,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162L] Omicron_BA.4andBA.5
.I-SF-.D..........G........D...SNK...R.NKAV....... 14 1 1 0 12 0 0 0 14 11 78% [T19I,L24-,P25-,P26-,A27S,H69F,V70-,S71-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..EY...V...HT.ISNK.PS.KNKAPS...... 14 1 3 10 0 0 0 0 14 14 100% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,D215Y,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D-......E..E....V...HT.ISNK.PS.KNKAPS...... 14 0 13 1 0 0 0 0 14 13 92% [T19I,L24-,P25-,P26-,A27S,G142D,Y144-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........DT..SNKRA.R.NKAA....... 14 0 0 14 0 0 0 0 14 13 92% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,P209L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,V445A,L452R,S477N,T478K,E484A,F486A,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNK.A.R.NKAV.....S. 14 0 0 0 14 0 0 0 14 11 78% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445A,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020S] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V..IHT.I.NK.PS.K.KAPS...... 14 0 14 0 0 0 0 0 14 12 85% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,T323I,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-..................D....NKT..RKNKAV....... 14 0 2 0 12 0 0 0 14 2 14% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,G339D,S371F,S373P,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,I666V,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNKN..RKNKAV....I.. 13 1 12 0 0 0 0 0 13 5 38% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K150E,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,T883I,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HT..NNKT.SRKNKAS....... 13 1 4 8 0 0 0 0 13 11 84% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408N,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HTT.SNK..S.KNKA.S.....S 13 1 3 1 8 0 0 0 13 10 76% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S]
.I-S--.D..N.......G........D...SNK...R.NKAV....... 13 0 5 1 7 0 0 0 13 5 38% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147N,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G...L....D...SNKT..RKNKAV....... 13 0 5 7 0 0 0 1 13 8 61% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,P251L,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,E619Q,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..G........HT.ISNK.PS.KNKAPS...... 13 0 3 10 0 0 0 0 13 6 46% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213G,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..QR.L...VG......S.HTT.SNK..S.KNKA.S...... 13 0 10 3 0 0 0 0 13 9 69% [T19I,L24-,P25-,P26-,A27S,G142D,K147Q,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.HTT.SNK..S.KNKAS....... 13 6 6 1 0 0 0 0 13 5 38% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,T572I,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,S1147L]
.I-S--LD-.........G........DS..SNKT..RKNKAV....... 13 13 0 0 0 0 0 0 13 12 92% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,V83L,G142D,Y144-,V213G,G339D,R346S,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..E..L...VG......S.HT..SNKT.SRKNKAS....... 13 0 9 1 3 0 0 0 13 6 46% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,F157L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S--.D-.........G........DT..SNK...R.NKAV....... 13 0 5 1 7 0 0 0 13 7 53% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,F220V,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........DT..SNKM..RKNKAV....... 13 0 2 9 1 1 0 0 13 11 84% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444M,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........DT...NK...R..KAV....... 13 0 13 0 0 0 0 0 13 7 53% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,L452R,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,N969K]
.I-S......ER.L..DVG......S.HT..SNKT.SRKNKAS....... 13 0 13 0 0 0 0 0 13 10 76% [T19I,L24-,P25-,P26-,A27S,K147E,W152R,F157L,N185D,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-SF-.D..........G........DT..SNK...R.NKAV....... 13 0 2 3 8 0 0 0 13 8 61% [T19I,L24-,P25-,P26-,A27S,H69F,V70-,S71-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D-.........G......S.DT..SNKT..RKNKAV....... 13 0 4 3 6 0 0 0 13 9 69% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G257S,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G..D.....DT..S.KT..RKNKAV....... 13 0 13 0 0 0 0 0 13 9 69% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248D,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D....T.....G.N....D.D...SNKT..MKNKR........ 13 0 0 0 13 0 0 0 13 10 76% [T19I,L24-,P25-,P26-,A27S,G142D,M153T,N164K,V213G,H245N,G257D,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,N450D,L452M,N460K,S477N,T478K,E484R,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I.---.D..........G........D...SNK...R.NKAV....... 13 0 1 0 12 0 0 0 13 8 61% [T19I,P25-,P26-,A27-,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,N450D,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNEAPS...... 13 1 2 10 0 0 0 0 13 7 53% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478E,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKALS...... 12 0 1 9 2 0 0 0 12 8 66% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486L,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L..DVG......S.HT..SNKT.SRKNKAS...A... 12 12 0 0 0 0 0 0 12 9 75% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,N185D,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,P621A,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.I.NK.PS.KNKAPS.H.... 12 0 5 0 7 0 0 0 12 11 91% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.I.NK.PS.KNKASS...... 12 0 0 3 5 0 4 0 12 6 50% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.L-S...D..ER.L...VG......S.HTT.SNK..S.KNKA.S...... 12 0 0 0 11 0 0 1 12 10 83% [T19L,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E.....G..HT.ISNK.PS.KNKASST..... 12 4 4 0 4 0 0 0 12 5 41% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,D253G,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,P521T,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG........HTT.SNK.AS.KNKA.S...... 12 0 0 0 12 0 0 0 12 6 50% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445A,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D.Y........G........D...SNK...R.NKAV....... 12 0 0 0 12 0 0 0 12 10 83% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,H146Y,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S.FAD-Q.....E..E....V...HT.ISNK.PS.KNKAPS.H.... 12 0 12 0 0 0 0 0 12 12 100% [T19I,L24-,P25-,P26-,A27S,V70F,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,I312V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..D.....DT..SNKT.VRKNKAV....... 12 1 11 0 0 0 0 0 12 11 91% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248D,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446V,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD.-.....E..E....V...HT.ISNK.PS.KNKASS...... 12 0 1 2 9 0 0 0 12 8 66% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y145X,H146-,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG........D...SNKT..RKNKAV....... 12 0 2 9 1 0 0 0 12 6 50% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,A688V,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D........Y.G........DT..SNKT..RKNKAV....... 12 0 0 12 0 0 0 0 12 9 75% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,N185Y,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........D...S.KT..RKNKAV....... 12 0 7 5 0 0 0 0 12 6 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q..V..E..E....V...HT.ISNK.PS.KNKAPS...... 12 2 2 7 1 0 0 0 12 10 83% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,M153V,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..S.....DT...NKT..RKNKAV....... 12 0 11 0 1 0 0 0 12 4 33% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248S,+248KW,+249DL,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,I1232V]
.I-S--.D-.........G........DT..SNK...RKNKA........ 12 0 12 0 0 0 0 0 12 11 91% [T19I,L24-,P25-,P26-,A27S,T29I,H69-,V70-,G142D,Y144-,V213G,L216F,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,N460K,S477N,T478K,N481S,G482-,E484A,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--..-.........G........DT...NKT..RKNKAV....... 12 0 12 0 0 0 0 0 12 6 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,Y144-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E.....G..HT.I.NK.PS.K.KASS.H.... 12 0 12 0 0 0 0 0 12 10 83% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,D253G,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,Q613H,D614G,H655Y,N679K,P681H,N764K,D796Y,N969K]
.I-S..AD-Q....EE..E....V...HT.ISNK.PS.KNKAPS...... 11 5 0 6 0 0 0 0 11 4 36% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,K182E,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,I997V]
.I-S...D..ER.L...VG......SIHT..SNKT.SRKNKAS....... 11 4 4 0 1 0 0 2 11 5 45% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,T323I,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.IS.K.PS.KNKAPSS..... 11 0 11 0 0 0 0 0 11 9 81% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,I410V,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,P521S,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q..I..E..E....V...HT.ISNK.PS.KNKAPS...... 11 0 3 8 0 0 0 0 11 9 81% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,M153I,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.....E...G..HL....DT..SNKT.RRKNKAV....... 11 11 0 0 0 0 0 0 11 11 100% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,K182E,V213G,Y248H,P251L,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446R,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E........HT.ISNKRPS.KNKASS...... 11 0 0 10 0 0 1 0 11 6 54% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,L858I,Q954H,N969K]
.I-S...D..........G..NS....DT..SNK...R.NKAV.....S. 11 0 0 11 0 0 0 0 11 10 90% [T19I,L24-,P25-,P26-,A27S,G142D,V213G,Y248N,P251S,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,L455F,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,T547I,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020S,Q1180K] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKASST..... 11 0 0 0 11 0 0 0 11 7 63% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,P521T,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-....L....G........DT..S.KT..RKNKAV....... 11 0 11 0 0 0 0 0 11 6 54% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,F157L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG...L..S.HT..SNKT.SRKNKAS....... 11 11 0 0 0 0 0 0 11 10 90% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,P251L,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAP....... 11 1 1 9 0 0 0 0 11 6 54% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G........D...SNK..DR.NKAV.....S. 11 0 0 0 11 0 0 0 11 7 63% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446D,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,S698L,N764K,D796Y,Q954H,N969K,A1020S,V1264L] Omicron_BA.4andBA.5
.I-S--.D-.........G........D...SNK...R.NKAV.....S. 11 0 0 0 11 0 0 0 11 6 54% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020S] Omicron_BA.4andBA.5
.I-S..AD-Q.....ES.E....V...HT.ISNK.PS.KNKAPS...... 11 9 1 0 0 1 0 0 11 9 81% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,N185S,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
FI-S--.D..........G........DT..SNK...R.NKAV.....S. 11 0 0 0 11 0 0 0 11 7 63% [L5F,T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,S254F,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,A1020S] Omicron_BA.4andBA.5
.I-S--.D-..................DT...NKT..RKNKAV....... 11 0 6 0 5 0 0 0 11 2 18% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,G339D,R346T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E.......V...HT.I.NK.PS.K.KAPS...... 11 0 11 0 0 0 0 0 11 7 63% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.L-S--.D..........G........D...SNK...R.NKAV....... 11 0 0 0 11 0 0 0 11 8 72% [T19L,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G.......ID...SNK...R.NKAV......S 11 0 0 0 11 0 0 0 11 10 90% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,T323I,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,T676I,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162S] Omicron_BA.4andBA.5
.I-S..AD-Q.....E..-....V...HT.ISNK.PS.KNKAPS...... 11 0 0 11 0 0 0 0 11 11 100% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,N211I,L212E,V213-,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG...H..S.HTT.SNK..S.KNKA.S...... 10 0 8 1 1 0 0 0 10 6 60% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,P251H,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..........G..N.....DT..SNK...R.NKAV....... 10 0 1 9 0 0 0 0 10 6 60% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248N,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G........D...SNKR..R.NKAV....... 10 0 1 0 9 0 0 0 10 3 30% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444R,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HTR.SNKT.SRKNKAS....... 10 10 0 0 0 0 0 0 10 9 90% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356R,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..IR......G........DT..SNKT..RKNKAV....... 10 0 7 0 1 0 0 2 10 8 80% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147I,W152R,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D......N...G........DT..SNKT..RKNKAV....... 10 1 8 1 0 0 0 0 10 7 70% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K182N,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G..H.....DT..SNK...R.NKAV....... 10 2 0 0 7 0 0 1 10 5 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248H,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G.......ID...SNKT..RKNKAV....... 10 0 0 10 0 0 0 0 10 5 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,T323I,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........E........D...SNKT..RKNKAV...S... 10 0 0 10 0 0 0 0 10 9 90% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213E,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,P621S,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.H.T.SNK..S.KNKA........ 10 5 2 0 3 0 0 0 10 5 50% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N450D,N460K,S477N,T478K,E484A,Q498R,N501Y,Y505H,D614G,P631S,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,D1153Y]
.I-S--.D..........G........DT..SNKT...KNKAV....... 10 0 10 0 0 0 0 0 10 6 60% [T19I,L24-,P25-,P26-,A27S,Y38X,P39X,D40X,K41X,V42X,F43X,R44X,S45X,S46X,V47X,L48X,H49X,S50X,T51X,Q52X,D53X,L54X,F55X,L56X,P57X,F58X,F59X,S60X,N61X,V62X,T63X,W64X,F65X,H69-,V70-,G142D,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D.......H..G........DT..SNKT..RKNKAV....... 10 0 3 2 5 0 0 0 10 6 60% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Q183H,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G..S.....DT..SNKTA.RKNKAV....... 10 0 10 0 0 0 0 0 10 7 70% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248S,+248KW,+249DL,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,V445A,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G....S...D...SNKN..RKNKAV....... 10 1 6 3 0 0 0 0 10 5 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,G252S,S255F,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444N,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D--........G........DT..SNKT..RK.NAV....... 10 10 0 0 0 0 0 0 10 10 100% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,H146-,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,G476-,T478N,+478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1143L]
.I-S--.D..IL......G........DT..SNKT..RKNKAV....... 10 1 8 1 0 0 0 0 10 10 100% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147I,W152L,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G.Y......DT..SNK...R.NKAV....... 10 0 4 0 6 0 0 0 10 4 40% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,H245Y,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D.Y........G........DT..SNKT..RKNKAV....... 10 0 4 6 0 0 0 0 10 9 90% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,H146Y,V213G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........G.-......DT..SNKT..RKNKAV....... 10 0 0 10 0 0 0 0 10 9 90% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,L244F,H245-,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L...VG......S.HTT.SNK..S.K.NA.S...... 10 0 3 0 7 0 0 0 10 6 60% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,G476-,T478N,+478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D..I..L....G........D...SNKT..RKNKAV....... 10 0 10 0 0 0 0 0 10 6 60% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,K147I,F157L,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
FI-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKASS...... 10 0 0 10 0 0 0 0 10 3 30% [L5F,T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,A852V,Q954H,N969K]
.I-S--.D-.........E........D...SNKT..RKNKAV....... 10 0 10 0 0 0 0 0 10 8 80% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213E,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS.....Q 10 0 0 9 1 0 0 0 10 9 90% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,P1162Q]
.I-S--.D..........G..H.....D...SNKT..RKNKAV....... 10 0 5 5 0 0 0 0 10 5 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,V213G,Y248H,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S......ER.L...VG........HTT.SN...S.KNKA.S...... 10 0 10 0 0 0 0 0 10 2 20% [T19I,L24-,P25-,P26-,A27S,K147E,W152R,F157L,I210V,V213G,A260X,G261X,A262X,A263X,A264X,Y265X,Y266X,V267X,G268X,Y269X,L270X,Q271X,P272X,R273X,T274X,F275X,L276X,L277X,K278X,Y279X,N280X,E281X,N282X,G283X,T284X,I285X,T286X,D287X,A288X,V289X,D290X,C291X,A292X,L293X,D294X,P295X,L296X,S297X,E298X,T299X,K300X,C301X,T302X,L303X,K304X,S305X,F306X,T307X,V308X,E309X,K310X,G311X,I312X,Y313X,Q314X,T315X,S316X,N317X,F318X,R319X,V320X,Q321X,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,G446S,N460K,T470N,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-......R..G.....G..DT..SNKT..RKNKAV....... 10 1 8 0 1 0 0 0 10 5 50% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,Q183R,V213G,D253G,G339D,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S--.D..........-........D...SNKT..R.NKAV....... 10 0 0 0 10 0 0 0 10 10 100% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,N211I,L212G,V213-,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-.........G........D...SNKT..R.NKAV....... 10 0 10 0 0 0 0 0 10 7 70% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,V213G,G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D-Q.....E..E....V...HT.I.NK.PS.KNKAPS...... 10 0 4 2 0 4 0 0 10 1 10% [T19I,L24-,P25-,P26-,A27S,D88X,G89X,V90D,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..A.-Q.....E..E....V...HT.ISNK.PS.KNKASS...... 10 0 3 4 0 0 3 0 10 6 60% [T19I,L24-,P25-,P26-,A27S,V83A,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486S,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S..AD-Q.....E..E....V...HT.ISNK.PS.KNKAPS..L... 10 2 3 5 0 0 0 0 10 7 70% [T19I,L24-,P25-,P26-,A27S,V83A,G142D,Y144-,H146Q,Q183E,V213E,G252V,G339H,R346T,L368I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,V445P,G446S,N460K,S477N,T478K,E484A,F486P,F490S,Q498R,N501Y,Y505H,D614G,P621L,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S--.D-....L....G........DI..SNKT..RKNKAV....... 10 0 10 0 0 0 0 0 10 7 70% [T19I,L24-,P25-,P26-,A27S,H69-,V70-,G142D,Y144-,F157L,V213G,G339D,R346I,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,L452R,N460K,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K] Omicron_BA.4andBA.5
.I-S...D..ER.L.L.VG......S.HT..SNKT.SRKNKAS....... 10 9 0 0 1 0 0 0 10 9 90% [V6F,T19I,L24-,P25-,P26-,A27S,N137S,G142D,K147E,W152R,F157L,Q183L,I210V,V213G,G257S,G339H,R346T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,F486S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.H.T..NK..S.KNKA.S...... 10 0 7 0 3 0 0 0 10 6 60% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,I210V,V213G,G257S,G339H,K356T,S371F,S373P,S375F,T376A,D405N,K417N,N440K,G446S,N450D,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-S...D..ER.L...VG......S.H....NKT.SRKNKA........ 10 0 0 0 10 0 0 0 10 5 50% [T19I,L24-,P25-,P26-,A27S,G142D,K147E,W152R,F157L,Y170X,V171X,S172X,Q173X,P174X,F175X,I210V,V213G,G257S,G339H,S371F,S373P,T376X,D405N,K417N,N440K,K444T,G446S,L452R,N460K,S477N,T478K,E484A,Q498R,N501Y,Y505H,D574V,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
.I-SY..D..ER.L...VG......S.HTT.SNK..S.KNKA.S...... 10 0 0 0 10 0 0 0 10 7 70% [T19I,L24-,P25-,P26-,A27S,H69Y,G142D,Y145H,K147E,W152R,F157L,I210V,V213G,G257S,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,G446S,N460K,S477N,T478K,E484A,F490S,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K]
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last modified: Sun Jan 22 23:41 2023
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