COVID-19 Viral Genome Analysis Pipeline
Enabled by data from
XSpike
eXplore the Spike protein sequence in the SARS CoV-2 virus
Last update: Aug 23, 2026
Delta and Omicron Variants
Global
Wuhan reference
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Evaluating 3178 sequences of length 1888
Sampled from 2026-06-12 to 2026-08-11.
Specified Date Range: ('2026-06-12', '2026-08-11')
Highest entropy sites for: Global
Site Entropy
445 1.3088
478 0.9968
346 0.7726
441 0.7455
31 0.7367
182 0.6984
190 0.6976
444 0.6923
59 0.6870
184 0.6774
16 0.0113
679 0.6653
446 0.6645
420 0.6557
19 0.6264
572 0.6171
493 0.5969
487 0.5960
26 0.5779
435 0.5726
529 0.5702
417 0.5516
253 0.5339
475 0.5021
27 0.4884
24 0.4840
25 0.4790
22 0.4562
1264 0.4364
641 0.4291
153 0.4073
681 0.3334
642 0.3318
213 0.3260
688 0.3253
483 0.3232
21 0.3126
264 0.3069
680 0.3066
245 0.3063
440 0.3031
251 0.3025
244 0.2943
486 0.2915
243 0.2895
1143 0.2895
704 0.2863
Most highly correlated site-pairs for: Global
cramerV mutInfo
445 478 0.6647 0.6919
59 184 0.9986 0.6760
346 190 0.9872 0.6550
31 190 0.9774 0.6369
346 182 0.9766 0.6346
182 190 0.9755 0.6342
346 31 0.5627 0.6320
31 182 0.9672 0.6101
478 487 0.9639 0.5375
59 420 0.9111 0.5187
184 420 0.9075 0.5131
572 487 0.9428 0.5112
417 253 0.9830 0.5099
478 572 0.9288 0.4901
441 475 0.9895 0.4803
244 243 0.9977 0.2780
445 245 0.9950 0.2685
245 244 0.9934 0.2859
245 243 0.9930 0.2725
445 251 0.9925 0.2670
445 244 0.9924 0.2644
445 243 0.9918 0.2495
251 244 0.9912 0.2822
251 243 0.9905 0.2688
19 22 0.9904 0.4270
245 251 0.9870 0.2810
264 244 0.9829 0.2745
26 486 0.9818 0.2645
264 243 0.9817 0.2611
445 486 0.9813 0.2599
Most common patterns for local area, where Local = Global
11
1111222222234444444444444455666666712
11222222355889144455641234444477888927447888046
69124567193240334513467050145658367392129018434
VTRTLPPASFMKGRVALHPDARKDANLKVGATVFNQKTNVNSPASPV Global UK Eu-UK NAmer Asia Africa SAmer Ocean Local Exact Pct [Context]
0 0 159 1134 984 101 88 712 2241 <----------- Totals
.ITN---S.S..S.G..N.GD.TNSK..HS..-P.E....K.R..L. 0 0 3 27 351 0 0 28 409 163 39% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417T,D420N,A435S,N440K,V445H,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---S.S..S.G..N..D.NNSK..PS..-P.E....K.R..L. 0 0 1 40 86 0 0 98 225 90 40% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,D420N,A435S,N440K,V445P,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP.IR.SG..N..DTN.SKRRPSV.-P......R.R..L. 0 0 15 62 67 0 0 33 177 95 53% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,M153I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,L441R,K444R,V445P,G446S,N450D,L452W,L455S,F456L,N460K,A475V,S477N,N481K,V483-,E484K,F486P,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679R,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
..T...L........--.S...N.SR..AD.N....N.KGR.HDL.. 0 0 8 21 30 1 0 64 124 44 35% [P9L,R21T,P26L,A67V,H69-,V70-,T95I,I101T,C136-,D138-,P139-,F140-,L141-,G142-,V143-,Y144-,Y145-,H146-,K147-,N149-,F157S,N164K,S172F,K187T,N211-,L212I,+214AS,+215TD,A243-,L244-,P251S,I326V,G339Y,A348P,K356T,S371F,S373P,S375F,R403K,D405N,R408S,K417N,A435S,N440R,V445A,G446D,L452W,N460K,S477N,T478N,E484K,G496S,Q498R,N501Y,K529N,E554D,A575S,E583D,D614G,H625R,N641K,V642G,E654K,H655Y,N679R,P681H,A688D,S704L,N764K,K795T,D796Y,A852K,S939F,Q954H,N969K,D1184E]
.ITN---SP..R.SG..N..DTN..K.RRN.K-PDE.I..K.R..L. 0 0 12 50 5 19 5 5 96 42 43% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445R,G446N,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L,A1174V]
.VTN---SP..R.SG..N..DTN.SKR.PSV.-P......K.R..LL 0 0 11 36 1 7 26 0 81 48 59% [+16MPLF,T19V,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,L441R,V445P,G446S,N450D,L452W,L455S,F456L,N460K,A475V,S477N,N481K,V483-,E484K,F486P,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,T791A,D796Y,S939F,Q954H,N969K,P1143L,V1264L]
.ITN---SP..R.SG..N..DTN.SK.RRS.K-PDE.I..K.R..L. 0 0 0 53 1 0 3 5 62 37 59% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN..K.RPS.K-PDE.I..K.R..L. 0 0 1 54 1 0 0 5 61 20 32% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,E96D,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445P,G446S,N450D,L452R,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN..KIRRN.K-PDETIK.K.R..L. 0 0 2 55 0 0 0 0 57 34 59% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,L441I,K444R,V445R,G446N,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,K529T,E554K,A570V,T572I,D614G,P621S,N641K,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---S.S..S.G..N.GD.TNSK..HS..-P.E....R.R..L. 0 0 0 9 27 0 0 5 41 25 60% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417T,D420N,A435S,N440K,V445H,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679R,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP.IR.SG..N..DTN.SKRRPSV.-P......R.R..LL 0 0 1 18 10 0 0 5 34 21 61% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,M153I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,L441R,K444R,V445P,G446S,N450D,L452W,L455S,F456L,N460K,A475V,S477N,N481K,V483-,E484K,F486P,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679R,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L,V1264L]
.ITN---SP..R.SG..N..DTN..K.RRS.K-PDETI..K.R..LL 0 0 0 32 0 1 1 0 34 18 52% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,K529T,E554K,A570V,T572I,T604I,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L,V1264L]
.ITN---S.S..S.G..N..D.NNSK..PS..-P.E....KPR..L. 0 0 0 2 24 0 0 1 27 13 48% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,D420N,A435S,N440K,V445P,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,S680P,P681R,N764K,D796Y,S939F,Q954Y,N969K,P1143L]
.ITN---SP..R.SG..N..DTN..K.RRS.K-PDE.IK.KPR..L. 0 0 0 23 0 0 2 0 25 21 84% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,N641K,H655Y,N679K,S680P,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---S.S..S.G..N.GD.TNSK..QS..-P.E....K.R..L. 0 0 0 20 4 0 0 1 25 15 60% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417T,D420N,A435S,N440K,V445Q,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
........P..R.SG..N..DTN..KIRRN.K-PDETIK.K.R..L. 0 0 0 24 0 0 0 0 24 11 45% [S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L441I,K444R,V445R,G446N,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,K529T,E554K,A570V,T572I,D614G,P621S,N641K,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---S.S..S.G..N..D.N.SK..HS..-P.E.I..K.R..L. 0 0 0 1 0 0 0 21 22 21 95% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,V445H,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---S.S..S.G..N..D.N.SK..PS..-P.E....K.R..L. 0 0 0 7 2 0 0 13 22 11 50% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,V445P,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
........P.IR.SG..N..DTN.SKRRPSV.-P......R.R..L. 0 0 0 3 18 0 0 0 21 20 95% [S31P,S50L,H69-,V70-,V127F,G142D,Y144-,M153I,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,L441R,K444R,V445P,G446S,N450D,L452W,L455S,F456L,N460K,A475V,S477N,N481K,V483-,E484K,F486P,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679R,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN..K.RRN.K-PDETI.GR.R..LL 0 0 4 12 0 4 0 0 20 6 30% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445R,G446N,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,K529T,N532S,E554K,A570V,T572I,Q613H,D614G,P621S,V642G,H655Y,N679R,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L,V1264L]
.ITN---SP..R.SG..N..DTN.SK.RRS.K-PDE.I..KFR..L. 0 0 0 6 0 0 12 0 18 6 33% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,K147Q,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,N532D,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,S680F,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN.SKRRPSVK-P......R.R..L. 0 0 0 18 0 0 0 0 18 18 100% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,L441R,K444R,V445P,G446S,N450D,L452W,L455S,F456L,N460K,A475V,S477N,T478K,N481K,V483-,E484K,F486P,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679R,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN..K..RS.E-P.E.I..R.R..LL 0 0 2 15 0 0 0 0 17 8 47% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478E,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679R,P681R,N764K,D796Y,S939F,Q954H,N969K,V1104L,P1143L,V1264L]
.........S..S.G..N..D.NNSK..PS..-P.E....K.R..L. 0 0 0 0 17 0 0 0 17 13 76% [S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,D420N,A435S,N440K,V445P,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN..KIRRS.K-PDETI..KPR..L. 0 0 0 12 3 0 0 1 16 8 50% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,L441I,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,K529T,N532K,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,S680P,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
........P..R.SG..N..DTN.SKR.PSV.-P......K.R..LL 0 0 2 13 0 0 0 0 15 9 60% [S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,L441R,V445P,G446S,N450D,L452W,L455S,F456L,N460K,A475V,S477N,N481K,V483-,E484K,F486P,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,T791A,D796Y,S939F,Q954H,N969K,P1143L,V1264L]
.......SP..R.SG..N..DTN.SKR.PSV.-P......K.R..LL 0 0 0 15 0 0 0 0 15 11 73% [A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,L441R,V445P,G446S,N450D,L452W,L455S,F456L,N460K,A475V,S477N,N481K,V483-,E484K,F486P,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,T791A,D796Y,S939F,Q954H,N969K,P1143L,V1264L]
.ITN---SP..R.SG..N..DTN..K.RRN.K-PDE.I..K.R..LL 0 0 1 7 0 5 0 1 14 8 57% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445R,G446N,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L,A1174V,V1264L]
.........S..S.G..N.GD.TNSK..HS..-P.E....K.R..L. 0 0 2 1 11 0 0 0 14 10 71% [S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417T,D420N,A435S,N440K,V445H,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---S.S..S.G..N.GDKTNSK..HS..-P.E....R.R..L. 0 0 0 1 13 0 0 0 14 8 57% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,G339H,R346K,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417T,D420N,A435S,N440K,V445H,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679R,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..D-N..K.RRS.K-PDE.IK.KPR..L. 0 0 2 0 0 0 11 0 13 7 53% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,W258-,A264D,I332V,G339H,+344S,R346-,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,N641K,H655Y,N679K,S680P,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN..K.RRS.K-PDE.I..K.R..L. 0 0 1 7 0 2 2 0 12 5 41% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,M177I,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN.SK.RRS.K-PDE.I..R.R..L. 0 0 0 1 7 0 0 4 12 5 41% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679R,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---S.S..S.G..N..D.N.SK..PS.I-P.E....K.R..L. 0 0 0 4 0 0 0 7 11 6 54% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,A435S,N440K,V445P,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478I,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---S.S..S.G..N.GDKTNSK..HS..-P.E....K.R..L. 0 0 0 0 11 0 0 0 11 9 81% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,G339H,R346K,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417T,D420N,A435S,N440K,V445H,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN..K.RRS.K-PDE.I..KPR..L. 0 0 0 9 0 0 1 0 10 7 70% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,S680P,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---S.S..S.G..N.GD.TNSK..HS..-P.E..K.K.R..L. 0 0 0 1 8 0 0 1 10 8 80% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S50L,F59S,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,G184S,N211-,L212I,V213G,L216F,H245N,D253G,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417T,D420N,A435S,N440K,V445H,G446S,N450D,L452W,L455S,F456L,N460K,S477N,N481K,V483-,E484K,F486P,Q493E,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,N641K,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
.ITN---SP..R.SG..N..DTN..K.RRN.K-PDE.I..K.H..L. 0 0 1 9 0 0 0 0 10 9 90% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,L335F,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,K444R,V445R,G446N,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,E554K,A570V,T572I,D614G,P621S,H655Y,N679K,P681H,N764K,D796Y,S939F,Q954H,N969K,P1143L,A1174V]
.ITN---SP..R.SG..N..DTN..KIRRS.K-PDETI....R..L. 0 0 0 6 2 0 0 2 10 3 30% [+16MPLF,T19I,R21T,T22N,L24-,P25-,P26-,A27S,S31P,S50L,H69-,V70-,V127F,G142D,Y144-,F157S,R158G,L176F,K182R,R190S,N211-,L212I,V213G,L216F,H245N,A264D,I332V,G339H,R346T,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,L441I,K444R,V445R,G446S,N450D,L452W,L455S,F456L,N460K,S477N,T478K,N481K,V483-,E484K,F486P,N487D,Q493E,Q498R,N501Y,Y505H,K529T,N532K,E554K,A570V,T572I,D614G,P621S,H655Y,Q675H,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L]
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last modified: Wed May 24 14:07 2023
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