Isotonic Regression on changing sites

Spike 222, Excluding the original form with D614Spike 477, Excluding the original form with D614Spike 501, Excluding the original form with D614

Spike 477, Excluding the original form with D614

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Assumption of the new AA increase over time: Country State/Province Local/City
Assumption of the new AA decrease over time: Country State/Province Local/City

Country, new AA increasing

State/Province, new AA increasing

Local/City, new AA increasing

Country, new AA decreasing

State/Province, new AA decreasing

Local/City, new AA decreasing